locus-tag	class	description
N4T41_00010	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_00090	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_00165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N4T41_00310	COG3173	Aminoglycoside phosphotransferase
N4T41_00315	COG0488	(ABC) transporter
N4T41_00335	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T41_00340	COG3657	addiction module killer protein
N4T41_00345	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_00375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N4T41_00400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T41_00410	COG2814	Major facilitator Superfamily
N4T41_00435	COG0657	acetylesterase activity
N4T41_00540	COG4974	Belongs to the 'phage' integrase family
N4T41_00655	COG1475	DNA binding
N4T41_00660	COG1192	Involved in chromosome partitioning
N4T41_00770	COG0789	Transcriptional regulator
N4T41_00780	COG0640	Transcriptional regulator
N4T41_00790	COG1230	cation diffusion facilitator family transporter
N4T41_00795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T41_01065	COG4372	Transposase
N4T41_01075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N4T41_01100	COG2963	transposase activity
N4T41_01110	COG4372	Transposase
N4T41_01125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N4T41_01145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T41_01155	COG5002	protein histidine kinase activity
N4T41_01160	COG0745	RESPONSE REGULATOR receiver
N4T41_01190	COG0860	N-Acetylmuramoyl-L-alanine amidase
N4T41_01215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N4T41_01320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N4T41_01380	COG4372	Transposase
N4T41_01400	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N4T41_01410	COG1525	nuclease
N4T41_01465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N4T41_01595	COG5410	chromosome segregation
N4T41_01700	COG1598	PFAM Uncharacterised protein family UPF0150
N4T41_01725	COG0739	heme binding
N4T41_01795	COG0582	viral genome integration into host DNA
N4T41_01805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N4T41_01815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N4T41_01830	COG0667	Aldo Keto reductase
N4T41_01845	COG1765	OsmC-like protein
N4T41_01860	COG0542	response to heat
N4T41_01895	COG2885	chlorophyll binding
N4T41_01905	COG0625	glutathione transferase activity
N4T41_01910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N4T41_01930	COG3634	alkyl hydroperoxide reductase activity
N4T41_01940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N4T41_01950	COG0450	alkyl hydroperoxide reductase
N4T41_01955	COG1643	Atp-dependent helicase
N4T41_01970	COG2814	Major facilitator Superfamily
N4T41_01975	COG3135	benzoate transporter
N4T41_01980	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_01985	COG0543	2 iron, 2 sulfur cluster binding
N4T41_01985	COG0633	Ferredoxin
N4T41_01995	COG4638	Rieske (2fe-2S)
N4T41_02005	COG0583	DNA-binding transcription factor activity
N4T41_02015	COG2871	sodium ion transport
N4T41_02100	COG1570	exodeoxyribonuclease VII activity
N4T41_02130	COG1280	lysine exporter protein (LysE YggA)
N4T41_02135	COG1278	Cold shock
N4T41_02175	COG2814	Major facilitator Superfamily
N4T41_02235	COG0210	DNA helicase
N4T41_02245	COG5377	YqaJ viral recombinase family
N4T41_02470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
N4T41_02480	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N4T41_02485	COG1137	ATPase activity
N4T41_02490	COG1538	Outer membrane efflux protein
N4T41_02520	COG4122	O-methyltransferase activity
N4T41_02530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N4T41_02545	COG1522	sequence-specific DNA binding
N4T41_02550	COG5006	permease, DMT superfamily
N4T41_02560	COG1560	Kdo2-lipid A biosynthetic process
N4T41_02575	COG2814	Major facilitator Superfamily
N4T41_02600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N4T41_02625	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T41_02670	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_02705	COG0583	DNA-binding transcription factor activity
N4T41_02710	COG1914	H( )-stimulated, divalent metal cation uptake system
N4T41_02730	COG4770	biotin carboxylase activity
N4T41_02735	COG0038	chloride channel
N4T41_02760	COG1063	alcohol dehydrogenase
N4T41_02775	COG0439	Biotin carboxylase
N4T41_02780	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T41_02785	COG1733	regulation of RNA biosynthetic process
N4T41_02795	COG0864	Transcriptional regulator
N4T41_02805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T41_02810	COG1116	anion transmembrane transporter activity
N4T41_02930	COG0590	tRNA wobble adenosine to inosine editing
N4T41_02935	COG2807	transmembrane transport
N4T41_02950	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N4T41_02960	COG0789	Transcriptional regulator
N4T41_02970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T41_02990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N4T41_03015	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_03020	COG0531	amino acid
N4T41_03025	COG1760	l-serine dehydratase
N4T41_03030	COG2030	dehydratase
N4T41_03030	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_03035	COG3396	Phenylacetate-CoA oxygenase
N4T41_03040	COG3460	Phenylacetate-CoA oxygenase
N4T41_03045	COG3396	Phenylacetate-CoA oxygenase
N4T41_03050	COG2151	metal-sulfur cluster biosynthetic enzyme
N4T41_03055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T41_03060	COG1024	Enoyl-CoA hydratase
N4T41_03065	COG1024	Enoyl-CoA hydratase
N4T41_03070	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T41_03075	COG0183	Belongs to the thiolase family
N4T41_03080	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
N4T41_03085	COG3327	negative regulation of DNA-templated transcription, initiation
N4T41_03095	COG2050	protein possibly involved in aromatic compounds catabolism
N4T41_03125	COG0753	catalase activity
N4T41_03130	COG3038	cytochrome b561
N4T41_03150	COG2267	carboxylic ester hydrolase activity
N4T41_03155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T41_03160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T41_03165	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_03175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N4T41_03190	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_03195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N4T41_03200	COG0583	DNA-binding transcription factor activity
N4T41_03210	COG1414	Transcriptional regulator
N4T41_03215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T41_03225	COG1840	ABC-type Fe3 transport system, periplasmic component
N4T41_03230	COG3842	ATPase activity
N4T41_03245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N4T41_03250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N4T41_03255	COG2814	Major facilitator Superfamily
N4T41_03260	COG1960	acyl-CoA dehydrogenase activity
N4T41_03275	COG1024	Enoyl-CoA hydratase
N4T41_03290	COG2192	nodulation
N4T41_03295	COG1280	lysine exporter protein (LysE YggA)
N4T41_03315	COG0183	Belongs to the thiolase family
N4T41_03320	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T41_03325	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_03330	COG1024	Enoyl-CoA hydratase
N4T41_03335	COG1960	acyl-CoA dehydrogenase activity
N4T41_03340	COG2814	Major facilitator Superfamily
N4T41_03345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N4T41_03350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N4T41_03360	COG2814	Major facilitator Superfamily
N4T41_03370	COG1960	acyl-CoA dehydrogenase activity
N4T41_03385	COG0583	DNA-binding transcription factor activity
N4T41_03395	COG4770	biotin carboxylase activity
N4T41_03400	COG1024	Enoyl-CoA hydratase
N4T41_03405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N4T41_03410	COG1960	acyl-CoA dehydrogenase activity
N4T41_03415	COG1309	transcriptional regulator
N4T41_03420	COG0318	PFAM AMP-dependent synthetase and ligase
N4T41_03440	COG0583	DNA-binding transcription factor activity
N4T41_03490	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_03510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N4T41_03530	COG0784	Response regulator, receiver
N4T41_03530	COG2205	protein histidine kinase activity
N4T41_03550	COG0765	amino acid transport
N4T41_03555	COG0765	amino acid transport
N4T41_03560	COG1126	abc transporter atp-binding protein
N4T41_03565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T41_03570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T41_03590	COG1280	lysine exporter protein (LysE YggA)
N4T41_03600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N4T41_03605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N4T41_03610	COG1045	serine acetyltransferase
N4T41_03625	COG0583	DNA-binding transcription factor activity
N4T41_03630	COG0625	glutathione transferase activity
N4T41_03635	COG0625	glutathione transferase activity
N4T41_03640	COG0583	DNA-binding transcription factor activity
N4T41_03650	COG1346	cytolysis
N4T41_03670	COG2814	Major facilitator Superfamily
N4T41_03680	COG0583	DNA-binding transcription factor activity
N4T41_03690	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
N4T41_03695	COG3052	prosthetic group binding
N4T41_03715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N4T41_03735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T41_03745	COG1294	oxidase, subunit
N4T41_03750	COG1271	oxidase subunit
N4T41_03770	COG0477	Major facilitator Superfamily
N4T41_03785	COG4521	taurine ABC transporter
N4T41_03795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T41_03800	COG2175	clavaminate synthase activity
N4T41_03810	COG1953	Uracil, thiamine, allantoin
N4T41_03820	COG0583	DNA-binding transcription factor activity
N4T41_03840	COG4372	Transposase
N4T41_03845	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N4T41_03860	COG0640	Transcriptional regulator
N4T41_03865	COG0798	PFAM Bile acid sodium symporter
N4T41_03870	COG0583	DNA-binding transcription factor activity
N4T41_03885	COG3634	alkyl hydroperoxide reductase activity
N4T41_03920	COG1301	dicarboxylic acid transport
N4T41_03925	COG0436	Aminotransferase
N4T41_03935	COG0386	Belongs to the glutathione peroxidase family
N4T41_03950	COG0436	Aminotransferase
N4T41_03975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N4T41_04000	COG0012	GTP binding
N4T41_04005	COG2011	ABC-type metal ion transport system permease component
N4T41_04010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N4T41_04020	COG1464	Belongs to the NlpA lipoprotein family
N4T41_04050	COG0765	amino acid transport
N4T41_04055	COG0765	amino acid transport
N4T41_04060	COG1126	abc transporter atp-binding protein
N4T41_04070	COG1522	sequence-specific DNA binding
N4T41_04085	COG1309	transcriptional regulator
N4T41_04115	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N4T41_04125	COG0697	spore germination
N4T41_04150	COG3121	Chaperone
N4T41_04155	COG3539	Fimbrial protein
N4T41_04180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N4T41_04180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N4T41_04225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N4T41_04235	COG2353	YceI-like domain
N4T41_04245	COG3698	Phosphodiester glycosidase
N4T41_04260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N4T41_04265	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N4T41_04265	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N4T41_04265	COG0506	proline dehydrogenase activity
N4T41_04275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N4T41_04280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N4T41_04300	COG1132	(ABC) transporter
N4T41_04305	COG3122	Protein conserved in bacteria
N4T41_04310	COG3619	membrane
N4T41_04320	COG0640	Transcriptional regulator
N4T41_04330	COG2850	peptidyl-arginine hydroxylation
N4T41_04335	COG0424	maF-like protein
N4T41_04355	COG0191	fructose-bisphosphate aldolase activity
N4T41_04360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N4T41_04375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N4T41_04385	COG1192	Involved in chromosome partitioning
N4T41_04390	COG1475	DNA binding
N4T41_04395	COG0811	peptide transport
N4T41_04405	COG1132	(ABC) transporter
N4T41_04410	COG1663	tetraacyldisaccharide 4'-kinase activity
N4T41_04430	COG0084	hydrolase, TatD family'
N4T41_04495	COG0776	regulation of translation
N4T41_04525	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N4T41_04530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N4T41_04580	COG0339	signal peptide processing
N4T41_04590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N4T41_04625	COG0702	epimerase
N4T41_04630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N4T41_04650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N4T41_04680	COG0316	Belongs to the HesB IscA family
N4T41_04685	COG0822	iron-sulfur transferase activity
N4T41_04710	COG0776	regulation of translation
N4T41_04715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N4T41_04720	COG2207	Transcriptional regulator
N4T41_04725	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T41_04730	COG1960	acyl-CoA dehydrogenase activity
N4T41_04735	COG1960	acyl-CoA dehydrogenase activity
N4T41_04750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N4T41_04765	COG2814	Major facilitator Superfamily
N4T41_04770	COG4264	IucA IucC family
N4T41_04775	COG4264	IucA IucC family
N4T41_04785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N4T41_04815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N4T41_04835	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N4T41_04840	COG0406	alpha-ribazole phosphatase activity
N4T41_04855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N4T41_04860	COG0730	response to heat
N4T41_04880	COG4773	Receptor
N4T41_04885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N4T41_04905	COG0842	Transport permease protein
N4T41_04910	COG0842	Transport permease protein
N4T41_04970	COG2226	methyltransferase
N4T41_04995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N4T41_05030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N4T41_05040	COG0133	tryptophan synthase activity
N4T41_05055	COG3706	GGDEF domain
N4T41_05070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N4T41_05075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N4T41_05080	COG0022	dehydrogenase e1 component
N4T41_05085	COG0508	dehydrogenase complex catalyzes the overall conversion of
N4T41_05100	COG1063	alcohol dehydrogenase
N4T41_05105	COG3781	membrane
N4T41_05115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T41_05115	COG3453	Protein conserved in bacteria
N4T41_05130	COG0730	response to heat
N4T41_05145	COG2207	Transcriptional regulator
N4T41_05145	COG3708	Transcriptional regulator
N4T41_05150	COG1733	regulation of RNA biosynthetic process
N4T41_05155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N4T41_05165	COG2188	Transcriptional regulator
N4T41_05180	COG4521	taurine ABC transporter
N4T41_05185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T41_05245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T41_05250	COG0431	NADPH-dependent FMN reductase
N4T41_05275	COG4691	Plasmid stability protein
N4T41_05310	COG0798	PFAM Bile acid sodium symporter
N4T41_05345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T41_05360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N4T41_05365	COG1538	Outer membrane efflux protein
N4T41_05370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T41_05375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T41_05385	COG0789	Transcriptional regulator
N4T41_05410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N4T41_05445	COG0477	Major facilitator Superfamily
N4T41_05455	COG1027	Aspartate ammonia-lyase
N4T41_05470	COG0583	DNA-binding transcription factor activity
N4T41_05475	COG0583	DNA-binding transcription factor activity
N4T41_05480	COG0183	Belongs to the thiolase family
N4T41_05485	COG2031	fatty acid transporter
N4T41_05500	COG0583	DNA-binding transcription factor activity
N4T41_05510	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_05525	COG1309	transcriptional regulator
N4T41_05540	COG2610	gluconate transmembrane transporter activity
N4T41_05545	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_05550	COG2207	Transcriptional regulator
N4T41_05565	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_05575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T41_05590	COG0543	2 iron, 2 sulfur cluster binding
N4T41_05590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T41_05595	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
N4T41_05600	COG4638	Rieske (2fe-2S)
N4T41_05610	COG0725	ABC transporter, periplasmic molybdate-binding protein
N4T41_05615	COG4149	molybdate abc transporter
N4T41_05620	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N4T41_05625	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_05630	COG3433	isochorismatase activity
N4T41_05630	COG1535	isochorismatase
N4T41_05710	COG0753	catalase activity
N4T41_05720	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N4T41_05755	COG2205	protein histidine kinase activity
N4T41_05775	COG2814	Major facilitator Superfamily
N4T41_05800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N4T41_05845	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_05890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N4T41_05910	COG1120	ATPase activity
N4T41_05915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N4T41_05925	COG1064	alcohol dehydrogenase
N4T41_05930	COG2207	Transcriptional regulator
N4T41_05935	COG2084	Dehydrogenase
N4T41_05945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N4T41_05950	COG0583	DNA-binding transcription factor activity
N4T41_05960	COG0129	dihydroxy-acid dehydratase activity
N4T41_05965	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_05970	COG1846	Transcriptional regulator
N4T41_05975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T41_05980	COG1960	acyl-CoA dehydrogenase activity
N4T41_06015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N4T41_06050	COG0583	DNA-binding transcription factor activity
N4T41_06065	COG2188	Transcriptional regulator
N4T41_06145	COG1960	acyl-CoA dehydrogenase activity
N4T41_06150	COG0583	DNA-binding transcription factor activity
N4T41_06155	COG1414	Transcriptional regulator
N4T41_06170	COG2391	methyltransferase activity
N4T41_06175	COG3293	Transposase
N4T41_06185	COG4993	Dehydrogenase
N4T41_06190	COG3659	wide pore channel activity
N4T41_06195	COG3420	alginic acid biosynthetic process
N4T41_06200	COG0710	3-dehydroquinate dehydratase activity
N4T41_06205	COG3485	protocatechuate 3,4-dioxygenase
N4T41_06210	COG3485	protocatechuate 3,4-dioxygenase
N4T41_06215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N4T41_06220	COG2271	Major facilitator Superfamily
N4T41_06225	COG0596	Alpha beta hydrolase
N4T41_06230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N4T41_06235	COG0183	Belongs to the thiolase family
N4T41_06240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N4T41_06245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N4T41_06255	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N4T41_06260	COG2323	membrane
N4T41_06305	COG0446	pyridine nucleotide-disulphide oxidoreductase
N4T41_06305	COG1902	pentaerythritol trinitrate reductase activity
N4T41_06330	COG0542	response to heat
N4T41_06335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N4T41_06375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N4T41_06380	COG0569	domain protein
N4T41_06385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N4T41_06410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N4T41_06420	COG1585	Membrane protein implicated in regulation of membrane protease activity
N4T41_06440	COG1294	oxidase, subunit
N4T41_06445	COG4890	Cyd operon protein YbgT
N4T41_06460	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
N4T41_06470	COG0552	protein localization to endoplasmic reticulum
N4T41_06495	COG0516	GMP reductase activity
N4T41_06495	COG0517	IMP dehydrogenase activity
N4T41_06500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N4T41_06505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N4T41_06515	COG0583	DNA-binding transcription factor activity
N4T41_06520	COG0024	Methionine aminopeptidase
N4T41_06550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N4T41_06550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N4T41_06555	COG1105	Belongs to the carbohydrate kinase PfkB family
N4T41_06560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N4T41_06560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N4T41_06560	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
N4T41_06580	COG3300	MHYT domain
N4T41_06580	COG5001	Diguanylate cyclase
N4T41_06595	COG2135	peptidase activity
N4T41_06600	COG0659	secondary active sulfate transmembrane transporter activity
N4T41_06620	COG1113	amino acid transport
N4T41_06630	COG1522	sequence-specific DNA binding
N4T41_06655	COG1011	Hydrolase
N4T41_06660	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N4T41_06670	COG2137	regulation of response to DNA damage stimulus
N4T41_06685	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N4T41_06720	COG0575	Belongs to the CDS family
N4T41_06725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N4T41_06750	COG3852	Histidine kinase
N4T41_06755	COG2204	response regulator
N4T41_06810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N4T41_06815	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
N4T41_06840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T41_06850	COG0303	'Molybdopterin
N4T41_06855	COG0315	cyclic pyranopterin monophosphate synthase activity
N4T41_06855	COG0521	Mo-molybdopterin cofactor biosynthetic process
N4T41_06870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N4T41_06875	COG0243	molybdopterin cofactor binding
N4T41_06885	COG0243	molybdopterin cofactor binding
N4T41_06890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T41_06905	COG0745	RESPONSE REGULATOR receiver
N4T41_06910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T41_06910	COG1116	anion transmembrane transporter activity
N4T41_06925	COG0511	ligase activity, forming carbon-carbon bonds
N4T41_06940	COG2814	Major facilitator Superfamily
N4T41_06960	COG0069	glutamate synthase activity
N4T41_06980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N4T41_06990	COG1454	alcohol dehydrogenase
N4T41_06995	COG0824	Thioesterase
N4T41_07020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N4T41_07025	COG2030	dehydratase
N4T41_07035	COG0183	Belongs to the thiolase family
N4T41_07045	COG0583	DNA-binding transcription factor activity
N4T41_07050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N4T41_07060	COG1522	sequence-specific DNA binding
N4T41_07065	COG3135	benzoate transporter
N4T41_07105	COG0589	response to stress
N4T41_07110	COG0488	(ABC) transporter
N4T41_07130	COG4773	Receptor
N4T41_07160	COG0668	transmembrane transport
N4T41_07170	COG1309	transcriptional regulator
N4T41_07190	COG1605	Chorismate mutase
N4T41_07210	COG0308	aminopeptidase N
N4T41_07235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T41_07240	COG1454	alcohol dehydrogenase
N4T41_07260	COG0531	amino acid
N4T41_07265	COG4303	Ethanolamine ammonia lyase large subunit
N4T41_07270	COG4302	ethanolamine ammonia-lyase activity
N4T41_07275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N4T41_07275	COG0519	Catalyzes the synthesis of GMP from XMP
N4T41_07280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N4T41_07305	COG0697	spore germination
N4T41_07310	COG1923	regulation of RNA biosynthetic process
N4T41_07320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N4T41_07325	COG0802	atpase or kinase
N4T41_07345	COG1187	pseudouridine synthase activity
N4T41_07375	COG2814	Major facilitator Superfamily
N4T41_07380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N4T41_07405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N4T41_07460	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_07470	COG2963	transposase activity
N4T41_07480	COG4372	Transposase
N4T41_07510	COG0592	DNA-directed DNA polymerase activity
N4T41_07550	COG2026	Addiction module toxin, RelE StbE family
N4T41_07770	COG1484	DNA-dependent DNA replication
N4T41_07865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T41_07905	COG0729	surface antigen
N4T41_07925	COG0174	glutamine synthetase
N4T41_07930	COG0745	RESPONSE REGULATOR receiver
N4T41_07935	COG2205	protein histidine kinase activity
N4T41_07945	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N4T41_07950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N4T41_07975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T41_07980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T41_07985	COG1960	acyl-CoA dehydrogenase activity
N4T41_08015	COG0583	DNA-binding transcription factor activity
N4T41_08030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T41_08040	COG3658	cytochrome
N4T41_08045	COG1215	transferase activity, transferring glycosyl groups
N4T41_08075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N4T41_08080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N4T41_08090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N4T41_08115	COG0305	Participates in initiation and elongation during chromosome replication
N4T41_08120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N4T41_08130	COG1305	Transglutaminase-like
N4T41_08140	COG2308	Evidence 4 Homologs of previously reported genes of
N4T41_08170	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N4T41_08175	COG0138	bifunctional purine biosynthesis protein purh
N4T41_08180	COG0151	Belongs to the GarS family
N4T41_08185	COG1464	Belongs to the NlpA lipoprotein family
N4T41_08190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N4T41_08195	COG2011	ABC-type metal ion transport system permease component
N4T41_08200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T41_08210	COG1301	dicarboxylic acid transport
N4T41_08245	COG1794	racemase activity, acting on amino acids and derivatives
N4T41_08255	COG3008	intermembrane lipid transfer
N4T41_08255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N4T41_08260	COG2995	paraquat-inducible protein a
N4T41_08270	COG2985	domain, Protein
N4T41_08285	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_08305	COG0477	Major facilitator Superfamily
N4T41_08355	COG2186	Transcriptional regulator
N4T41_08365	COG0786	glutamate:sodium symporter activity
N4T41_08370	COG3243	poly(R)-hydroxyalkanoic acid synthase
N4T41_08395	COG3111	PFAM Bacterial OB fold (BOF) protein
N4T41_08475	COG3210	domain, Protein
N4T41_08475	COG3210	domain, Protein
N4T41_08480	COG2831	hemolysin activation secretion protein
N4T41_08545	COG1610	YqeY-like protein
N4T41_08575	COG1286	toxin biosynthetic process
N4T41_08605	COG0778	Nitroreductase
N4T41_08615	COG0513	Belongs to the DEAD box helicase family
N4T41_08640	COG2363	Small membrane protein
N4T41_08670	COG1234	tRNA 3'-trailer cleavage
N4T41_08675	COG2195	Cleaves the N-terminal amino acid of tripeptides
N4T41_08685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N4T41_08695	COG2819	hydrolase of the alpha beta superfamily
N4T41_08700	COG1960	acyl-CoA dehydrogenase activity
N4T41_08705	COG1301	dicarboxylic acid transport
N4T41_08710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N4T41_08715	COG3139	Protein of unknown function (DUF1315)
N4T41_08720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N4T41_08725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N4T41_08735	COG0494	nUDIX hydrolase
N4T41_08745	COG0642	Histidine kinase
N4T41_08760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N4T41_08770	COG1720	tRNA m6t6A37 methyltransferase activity
N4T41_08785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T41_08790	COG0826	peptidase U32
N4T41_08795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T41_08805	COG4598	ABC transporter
N4T41_08810	COG4160	amino acid transport
N4T41_08815	COG4215	(ABC) transporter
N4T41_08840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T41_08960	COG0739	heme binding
N4T41_09275	COG0582	viral genome integration into host DNA
N4T41_09280	COG1131	(ABC) transporter
N4T41_09285	COG0842	Transport permease protein
N4T41_09300	COG0772	Belongs to the SEDS family
N4T41_09305	COG2951	lytic endotransglycosylase activity
N4T41_09330	COG2207	Transcriptional regulator
N4T41_09345	COG0052	Belongs to the universal ribosomal protein uS2 family
N4T41_09350	COG0024	Methionine aminopeptidase
N4T41_09360	COG2223	nitrite transmembrane transporter activity
N4T41_09370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T41_09375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N4T41_09380	COG1960	acyl-CoA dehydrogenase activity
N4T41_09395	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N4T41_09400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N4T41_09405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N4T41_09435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N4T41_09440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N4T41_09445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N4T41_09480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N4T41_09490	COG0174	glutamine synthetase
N4T41_09505	COG0582	viral genome integration into host DNA
N4T41_09580	COG1598	PFAM Uncharacterised protein family UPF0150
N4T41_09700	COG5410	chromosome segregation
N4T41_09875	COG0512	Glutamine amidotransferase of anthranilate synthase
N4T41_09910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N4T41_09920	COG0302	gtp cyclohydrolase
N4T41_09945	COG3739	integral membrane protein
N4T41_09960	COG1169	isochorismate synthase
N4T41_09970	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N4T41_09975	COG1132	(ABC) transporter
N4T41_09980	COG1132	(ABC) transporter
N4T41_09990	COG1535	isochorismatase
N4T41_09990	COG3433	isochorismatase activity
N4T41_09995	COG1021	2,3-dihydroxybenzoate-AMP ligase
N4T41_10000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T41_10010	COG4774	siderophore transport
N4T41_10015	COG4607	ABC-type enterochelin transport system periplasmic component
N4T41_10020	COG4604	ABC transporter, ATP-binding protein
N4T41_10030	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N4T41_10035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T41_10050	COG2964	Protein conserved in bacteria
N4T41_10060	COG1741	Belongs to the pirin family
N4T41_10080	COG2879	small protein
N4T41_10085	COG1966	Carbon starvation protein
N4T41_10105	COG4943	cyclic-guanylate-specific phosphodiesterase activity
N4T41_10125	COG2211	Major facilitator Superfamily
N4T41_10130	COG1067	ATP-dependent peptidase activity
N4T41_10135	COG0583	DNA-binding transcription factor activity
N4T41_10160	COG1686	Belongs to the peptidase S11 family
N4T41_10165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N4T41_10200	COG0616	signal peptide processing
N4T41_10205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N4T41_10215	COG0573	inorganic phosphate transmembrane transporter activity
N4T41_10220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N4T41_10225	COG1113	amino acid transport
N4T41_10230	COG3961	Belongs to the TPP enzyme family
N4T41_10235	COG1522	sequence-specific DNA binding
N4T41_10245	COG0076	glutamate decarboxylase activity
N4T41_10250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N4T41_10260	COG1309	transcriptional regulator
N4T41_10275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T41_10310	COG0352	thiamine-phosphate diphosphorylase activity
N4T41_10335	COG0612	Peptidase, M16
N4T41_10345	COG1823	symporter activity
N4T41_10350	COG0583	DNA-binding transcription factor activity
N4T41_10355	COG0477	Major facilitator Superfamily
N4T41_10380	COG1187	pseudouridine synthase activity
N4T41_10395	COG1686	Belongs to the peptidase S11 family
N4T41_10400	COG1252	NADH dehydrogenase
N4T41_10410	COG0415	Belongs to the DNA photolyase family
N4T41_10425	COG1215	transferase activity, transferring glycosyl groups
N4T41_10455	COG2070	2-Nitropropane dioxygenase
N4T41_10510	COG0556	nucleotide-excision repair
N4T41_10520	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_10535	COG0436	Aminotransferase
N4T41_10575	COG4221	oxidoreductase activity
N4T41_10585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N4T41_10590	COG1381	Involved in DNA repair and RecF pathway recombination
N4T41_10600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N4T41_10615	COG0681	Belongs to the peptidase S26 family
N4T41_10655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N4T41_10660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N4T41_10670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N4T41_10675	COG4208	sulfate ABC transporter
N4T41_10680	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N4T41_10685	COG0583	DNA-binding transcription factor activity
N4T41_10690	COG4625	pathogenesis
N4T41_10705	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N4T41_10720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N4T41_10730	COG1056	cytidyltransferase-related domain
N4T41_10730	COG1051	belongs to the nudix hydrolase family
N4T41_10735	COG1024	Enoyl-CoA hydratase
N4T41_10750	COG2814	Major facilitator Superfamily
N4T41_10755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N4T41_10755	COG0047	phosphoribosylformylglycinamidine synthase activity
N4T41_10775	COG1473	amidohydrolase
N4T41_10780	COG0824	Thioesterase
N4T41_10800	COG0823	Involved in the tonB-independent uptake of proteins
N4T41_10820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N4T41_10855	COG0628	permease
N4T41_10865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N4T41_10870	COG0596	Alpha beta hydrolase
N4T41_10875	COG0616	signal peptide processing
N4T41_10875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N4T41_10885	COG2333	competence protein COMEC
N4T41_10885	COG0658	competence protein
N4T41_10890	COG1136	(ABC) transporter
N4T41_10895	COG4591	ABC-type transport system involved in lipoprotein release permease component
N4T41_10930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T41_10950	COG0463	Glycosyl transferase, family 2
N4T41_10980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N4T41_10985	COG1280	lysine exporter protein (LysE YggA)
N4T41_10995	COG0019	diaminopimelate decarboxylase activity
N4T41_11005	COG1113	amino acid transport
N4T41_11020	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
N4T41_11030	COG3339	Conserved Protein
N4T41_11035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N4T41_11040	COG0243	molybdopterin cofactor binding
N4T41_11045	COG1929	Belongs to the glycerate kinase type-1 family
N4T41_11060	COG0778	Nitroreductase
N4T41_11105	COG3811	Belongs to the UPF0386 family
N4T41_11115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T41_11140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N4T41_11160	COG0741	lytic transglycosylase activity
N4T41_11180	COG0584	glycerophosphoryl diester phosphodiesterase
N4T41_11215	COG1597	lipid kinase activity
N4T41_11230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N4T41_11235	COG0477	Major facilitator Superfamily
N4T41_11285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N4T41_11290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N4T41_11315	COG0505	Belongs to the CarA family
N4T41_11335	COG0589	response to stress
N4T41_11350	COG2843	Capsule synthesis protein
N4T41_11370	COG2321	neutral zinc metallopeptidase
N4T41_11375	COG2354	Protein conserved in bacteria
N4T41_11395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T41_11420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N4T41_11425	COG1053	succinate dehydrogenase
N4T41_11430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N4T41_11435	COG2009	succinate dehydrogenase
N4T41_11470	COG2921	Belongs to the UPF0250 family
N4T41_11475	COG0321	lipoyl(octanoyl) transferase activity
N4T41_11490	COG0531	amino acid
N4T41_11500	COG1733	regulation of RNA biosynthetic process
N4T41_11505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N4T41_11510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N4T41_11510	COG1648	precorrin-2 dehydrogenase activity
N4T41_11525	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N4T41_11550	COG0215	cysteine-tRNA ligase activity
N4T41_11555	COG0671	phosphoesterase, PA-phosphatase related
N4T41_11560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T41_11570	COG1538	Outer membrane efflux protein
N4T41_11575	COG0393	Putative heavy-metal-binding
N4T41_11580	COG0393	Putative heavy-metal-binding
N4T41_11590	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_11600	COG0525	valine-tRNA ligase activity
N4T41_11625	COG0004	ammonium transporteR
N4T41_11635	COG0642	Histidine kinase
N4T41_11640	COG0745	RESPONSE REGULATOR receiver
N4T41_11645	COG2194	sulfuric ester hydrolase activity
N4T41_11665	COG1752	Esterase of the alpha-beta hydrolase superfamily
N4T41_11680	COG2315	Protein conserved in bacteria
N4T41_11685	COG0142	geranyltranstransferase activity
N4T41_11690	COG2828	Protein conserved in bacteria
N4T41_11695	COG1113	amino acid transport
N4T41_11705	COG0582	viral genome integration into host DNA
N4T41_11745	COG0305	Participates in initiation and elongation during chromosome replication
N4T41_11795	COG0489	protein tyrosine kinase activity
N4T41_11805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T41_11805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T41_11835	COG2515	1-aminocyclopropane-1-carboxylate deaminase
N4T41_11840	COG2081	HI0933 family
N4T41_11850	COG0668	transmembrane transport
N4T41_11870	COG0583	DNA-binding transcription factor activity
N4T41_11890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N4T41_11895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N4T41_11925	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N4T41_11965	COG0745	RESPONSE REGULATOR receiver
N4T41_11985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N4T41_11995	COG0384	phenazine biosynthesis protein PhzF
N4T41_12055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T41_12085	COG0583	DNA-binding transcription factor activity
N4T41_12100	COG0583	DNA-binding transcription factor activity
N4T41_12105	COG1053	succinate dehydrogenase
N4T41_12115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N4T41_12120	COG2814	Major facilitator Superfamily
N4T41_12125	COG1960	acyl-CoA dehydrogenase activity
N4T41_12130	COG0583	DNA-binding transcription factor activity
N4T41_12135	COG1063	alcohol dehydrogenase
N4T41_12165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N4T41_12170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N4T41_12175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N4T41_12195	COG2132	Multicopper oxidase
N4T41_12205	COG0561	phosphatase activity
N4T41_12210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N4T41_12220	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N4T41_12235	COG1214	PFAM Peptidase M22, glycoprotease
N4T41_12295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N4T41_12300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N4T41_12305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N4T41_12365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N4T41_12375	COG1846	Transcriptional regulator
N4T41_12380	COG1764	response to oxidative stress
N4T41_12420	COG0037	tRNA processing
N4T41_12430	COG0248	Ppx GppA phosphatase
N4T41_12460	COG0072	phenylalanine-tRNA ligase activity
N4T41_12500	COG1238	metal cluster binding
N4T41_12505	COG0625	glutathione transferase activity
N4T41_12520	COG0318	PFAM AMP-dependent synthetase and ligase
N4T41_12525	COG3028	Belongs to the UPF0307 family
N4T41_12530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N4T41_12550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N4T41_12555	COG0617	tRNA 3'-terminal CCA addition
N4T41_12560	COG1555	photosystem II stabilization
N4T41_12565	COG3956	TIGRFAM MazG family protein
N4T41_12575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N4T41_12595	COG0784	Response regulator, receiver
N4T41_12595	COG2205	protein histidine kinase activity
N4T41_12595	COG5002	protein histidine kinase activity
N4T41_12600	COG1024	Enoyl-CoA hydratase
N4T41_12605	COG2084	Dehydrogenase
N4T41_12610	COG3622	Belongs to the hyi family
N4T41_12640	COG0697	spore germination
N4T41_12650	COG2814	Major facilitator Superfamily
N4T41_12655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N4T41_12665	COG0583	DNA-binding transcription factor activity
N4T41_12675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N4T41_12690	COG0084	hydrolase, TatD family'
N4T41_12705	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N4T41_12715	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_12725	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_12750	COG0440	acetolactate synthase activity
N4T41_12755	COG0028	Belongs to the TPP enzyme family
N4T41_12780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T41_12785	COG0577	efflux transmembrane transporter activity
N4T41_12785	COG1136	(ABC) transporter
N4T41_12790	COG1538	Outer membrane efflux protein
N4T41_12805	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N4T41_12810	COG1162	GTPase activity
N4T41_12820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N4T41_12860	COG1426	Protein conserved in bacteria
N4T41_12895	COG0793	Belongs to the peptidase S41A family
N4T41_12910	COG2267	carboxylic ester hydrolase activity
N4T41_12920	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_12925	COG3265	gluconokinase activity
N4T41_12935	COG0800	Aldolase
N4T41_12945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N4T41_12950	COG0280	phosphate acetyltransferase
N4T41_12950	COG0857	belongs to the CobB CobQ family
N4T41_12955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
N4T41_12955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
N4T41_12975	COG0740	serine-type endopeptidase activity
N4T41_12985	COG4774	siderophore transport
N4T41_12995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N4T41_13005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N4T41_13005	COG2813	Specifically methylates the guanine in position
N4T41_13105	COG0788	formyltetrahydrofolate deformylase activity
N4T41_13130	COG4651	solute:proton antiporter activity
N4T41_13130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N4T41_13150	COG0724	RNA recognition motif
N4T41_13155	COG0210	DNA helicase
N4T41_13180	COG1733	regulation of RNA biosynthetic process
N4T41_13190	COG2900	Belongs to the SlyX family
N4T41_13195	COG0488	(ABC) transporter
N4T41_13200	COG1280	lysine exporter protein (LysE YggA)
N4T41_13205	COG1560	Kdo2-lipid A biosynthetic process
N4T41_13215	COG1301	dicarboxylic acid transport
N4T41_13270	COG0473	3-isopropylmalate dehydrogenase activity
N4T41_13335	COG0583	DNA-binding transcription factor activity
N4T41_13345	COG0625	glutathione transferase activity
N4T41_13350	COG2378	regulation of single-species biofilm formation
N4T41_13355	COG0546	phosphoglycolate phosphatase activity
N4T41_13365	COG1530	ribonuclease E activity
N4T41_13370	COG0318	PFAM AMP-dependent synthetase and ligase
N4T41_13385	COG0583	DNA-binding transcription factor activity
N4T41_13390	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_13395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N4T41_13405	COG0534	Mate efflux family protein
N4T41_13420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N4T41_13450	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T41_13450	COG0493	'glutamate synthase
N4T41_13460	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
N4T41_13465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T41_13480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N4T41_13490	COG0644	oxidoreductase
N4T41_13490	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
N4T41_13495	COG0425	Belongs to the sulfur carrier protein TusA family
N4T41_13500	COG4535	Mg2 and Co2 transporter CorC
N4T41_13510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T41_13530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N4T41_13535	COG0475	glutathione-regulated potassium exporter activity
N4T41_13535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N4T41_13550	COG0484	heat shock protein binding
N4T41_13555	COG0789	Transcriptional regulator
N4T41_13560	COG0598	Magnesium transport protein CorA
N4T41_13575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N4T41_13580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T41_13585	COG1074	ATP-dependent DNA helicase activity
N4T41_13590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
N4T41_13610	COG2226	methyltransferase
N4T41_13620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N4T41_13630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N4T41_13645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N4T41_13645	COG2111	Na H antiporter
N4T41_13650	COG1006	Multisubunit Na H antiporter MnhC subunit
N4T41_13655	COG0651	ATP synthesis coupled electron transport
N4T41_13660	COG1863	multisubunit Na H antiporter MnhE subunit
N4T41_13665	COG2212	antiporter activity
N4T41_13670	COG1320	monovalent cation:proton antiporter activity
N4T41_13685	COG0195	Participates in both transcription termination and antitermination
N4T41_13735	COG0237	dephospho-CoA kinase activity
N4T41_13745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N4T41_13760	COG0497	DNA recombination
N4T41_13770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N4T41_13800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N4T41_13800	COG2169	Transcriptional regulator
N4T41_13805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N4T41_13875	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N4T41_13890	COG0326	Molecular chaperone. Has ATPase activity
N4T41_13905	COG2056	Na+-H+ antiporter family
N4T41_13910	COG0596	Alpha beta hydrolase
N4T41_14010	COG0546	phosphoglycolate phosphatase activity
N4T41_14015	COG1716	ATPase activity
N4T41_14060	COG0181	hydroxymethylbilane synthase activity
N4T41_14070	COG3275	phosphorelay sensor kinase activity
N4T41_14090	COG1538	Outer membrane efflux protein
N4T41_14095	COG0697	spore germination
N4T41_14120	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N4T41_14125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N4T41_14130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N4T41_14135	COG0772	Belongs to the SEDS family
N4T41_14160	COG4974	Belongs to the 'phage' integrase family
N4T41_14165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T41_14175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N4T41_14185	COG2197	response regulator
N4T41_14200	COG0793	Belongs to the peptidase S41A family
N4T41_14205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N4T41_14210	COG0795	lipopolysaccharide-transporting ATPase activity
N4T41_14250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N4T41_14250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N4T41_14260	COG0004	ammonium transporteR
N4T41_14265	COG0347	Belongs to the P(II) protein family
N4T41_14285	COG0659	secondary active sulfate transmembrane transporter activity
N4T41_14290	COG0589	response to stress
N4T41_14335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T41_14345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T41_14370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N4T41_14385	COG0318	PFAM AMP-dependent synthetase and ligase
N4T41_14395	COG0477	Major facilitator Superfamily
N4T41_14400	COG2860	membrane
N4T41_14410	COG1253	flavin adenine dinucleotide binding
N4T41_14430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N4T41_14470	COG0655	NAD(P)H dehydrogenase (quinone) activity
N4T41_14480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N4T41_14550	COG0758	DNA mediated transformation
N4T41_14560	COG0697	spore germination
N4T41_14565	COG1309	transcriptional regulator
N4T41_14580	COG0386	Belongs to the glutathione peroxidase family
N4T41_14645	COG1121	(ABC) transporter
N4T41_14650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N4T41_14655	COG1280	lysine exporter protein (LysE YggA)
N4T41_14660	COG2837	iron assimilation
N4T41_14670	COG0281	malic enzyme
N4T41_14715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N4T41_14715	COG0519	Catalyzes the synthesis of GMP from XMP
N4T41_14720	COG4399	Belongs to the UPF0754 family
N4T41_14725	COG2259	Doxx family
N4T41_14730	COG0586	Pfam SNARE associated Golgi protein
N4T41_14745	COG1192	Involved in chromosome partitioning
N4T41_14755	COG0271	Belongs to the BolA IbaG family
N4T41_14775	COG2267	carboxylic ester hydrolase activity
N4T41_14795	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N4T41_14795	COG3321	synthase
N4T41_14795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N4T41_14795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N4T41_14800	COG1960	acyl-CoA dehydrogenase activity
N4T41_14810	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_14815	COG2197	response regulator
N4T41_14825	COG3916	Acyl-homoserine-lactone synthase
N4T41_14830	COG0477	Major facilitator Superfamily
N4T41_14835	COG1024	Enoyl-CoA hydratase
N4T41_14840	COG1024	Enoyl-CoA hydratase
N4T41_14845	COG1960	acyl-CoA dehydrogenase activity
N4T41_14850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T41_14870	COG1113	amino acid transport
N4T41_14875	COG1113	amino acid transport
N4T41_14880	COG0251	oxidation-reduction process
N4T41_14920	COG0564	pseudouridine synthase activity
N4T41_14980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N4T41_14995	COG1802	Transcriptional regulator
N4T41_15005	COG1448	Aminotransferase
N4T41_15010	COG0277	FAD linked oxidase domain protein
N4T41_15020	COG2186	Transcriptional regulator
N4T41_15030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T41_15035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N4T41_15050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N4T41_15055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N4T41_15060	COG1216	Glycosyl transferase, family 2
N4T41_15090	COG2089	acid synthase
N4T41_15105	COG1083	cytidylyl-transferase
N4T41_15110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N4T41_15115	COG1086	Polysaccharide biosynthesis protein
N4T41_15120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N4T41_15125	COG1596	polysaccharide export
N4T41_15150	COG0728	peptidoglycan biosynthetic process
N4T41_15155	COG3023	N-Acetylmuramoyl-L-alanine amidase
N4T41_15215	COG0546	phosphoglycolate phosphatase activity
N4T41_15220	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_15240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T41_15245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T41_15250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T41_15255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T41_15260	COG1116	anion transmembrane transporter activity
N4T41_15265	COG1309	transcriptional regulator
N4T41_15270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N4T41_15280	COG0196	riboflavin kinase activity
N4T41_15285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N4T41_15295	COG1047	Peptidyl-prolyl cis-trans
N4T41_15335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N4T41_15340	COG0657	acetylesterase activity
N4T41_15360	COG0583	DNA-binding transcription factor activity
N4T41_15390	COG2951	lytic endotransglycosylase activity
N4T41_15395	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N4T41_15410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N4T41_15420	COG0671	phosphoesterase, PA-phosphatase related
N4T41_15425	COG0861	Integral membrane protein TerC family
N4T41_15435	COG0754	glutathionylspermidine amidase activity
N4T41_15445	COG0402	S-adenosylhomocysteine deaminase activity
N4T41_15460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T41_15465	COG1230	cation diffusion facilitator family transporter
N4T41_15480	COG0706	membrane insertase activity
N4T41_15505	COG0592	DNA-directed DNA polymerase activity
N4T41_15515	COG0187	DNA topoisomerase II activity
N4T41_15525	COG0586	Pfam SNARE associated Golgi protein
N4T41_15530	COG0488	(ABC) transporter
N4T41_15555	COG0596	Alpha beta hydrolase
N4T41_15560	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N4T41_15565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N4T41_15605	COG0733	neurotransmitter:sodium symporter activity
N4T41_15640	COG0583	DNA-binding transcription factor activity
N4T41_15645	COG2233	PERMEase
N4T41_15660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T41_15695	COG2814	Major facilitator Superfamily
N4T41_15700	COG0656	L-ascorbic acid biosynthetic process
N4T41_15705	COG0583	DNA-binding transcription factor activity
N4T41_15720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T41_15725	COG1064	alcohol dehydrogenase
N4T41_15730	COG2818	Glycosylase
N4T41_15745	COG1194	a g-specific adenine glycosylase
N4T41_15765	COG2983	Belongs to the UPF0260 family
N4T41_15780	COG1335	isochorismatase
N4T41_15785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T41_15805	COG2116	formate transmembrane transporter activity
N4T41_15810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N4T41_15905	COG0534	Mate efflux family protein
N4T41_15910	COG1683	Conserved Protein
N4T41_15930	COG0625	glutathione transferase activity
N4T41_15940	COG1113	amino acid transport
N4T41_15950	COG0523	cobalamin synthesis protein
N4T41_15960	COG2188	Transcriptional regulator
N4T41_15990	COG0010	Belongs to the arginase family
N4T41_16005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N4T41_16010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N4T41_16020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N4T41_16025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N4T41_16110	COG0534	Mate efflux family protein
N4T41_16115	COG0436	Aminotransferase
N4T41_16120	COG2733	membrane
N4T41_16135	COG2918	glutathione biosynthetic process
N4T41_16180	COG3150	esterase
N4T41_16190	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
N4T41_16200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T41_16210	COG2233	PERMEase
N4T41_16215	COG2351	hydroxyisourate hydrolase activity
N4T41_16250	COG3706	GGDEF domain
N4T41_16265	COG1393	Belongs to the ArsC family
N4T41_16270	COG0708	Exodeoxyribonuclease III
N4T41_16285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N4T41_16305	COG0189	ligase activity
N4T41_16325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N4T41_16335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N4T41_16350	COG4942	peptidase
N4T41_16360	COG0508	dehydrogenase complex catalyzes the overall conversion of
N4T41_16370	COG2119	membrane
N4T41_16375	COG4774	siderophore transport
N4T41_16380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T41_16380	COG0426	domain, Protein
N4T41_16405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N4T41_16425	COG1902	pentaerythritol trinitrate reductase activity
N4T41_16430	COG1519	Transferase
N4T41_16435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N4T41_16440	COG0668	transmembrane transport
N4T41_16450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T41_16455	COG1335	isochorismatase
N4T41_16460	COG1522	sequence-specific DNA binding
N4T41_16485	COG2205	protein histidine kinase activity
N4T41_16485	COG0784	Response regulator, receiver
N4T41_16485	COG2198	Histidine kinase
N4T41_16490	COG3162	membrane
N4T41_16495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N4T41_16520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N4T41_16525	COG1309	transcriptional regulator
N4T41_16545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N4T41_16545	COG0352	thiamine-phosphate diphosphorylase activity
N4T41_16545	COG0351	phosphomethylpyrimidine kinase
N4T41_16555	COG2814	Major facilitator Superfamily
N4T41_16570	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N4T41_16580	COG1113	amino acid transport
N4T41_16590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N4T41_16595	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_16605	COG1335	isochorismatase
N4T41_16640	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N4T41_16640	COG2508	Transcriptional regulator
N4T41_16670	COG4372	Transposase
N4T41_16675	COG1113	amino acid transport
N4T41_16685	COG2814	Major facilitator Superfamily
N4T41_16690	COG0583	DNA-binding transcription factor activity
N4T41_16710	COG0667	Aldo Keto reductase
N4T41_16745	COG1733	regulation of RNA biosynthetic process
N4T41_16750	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T41_16815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N4T41_16830	COG2329	Antibiotic biosynthesis monooxygenase
N4T41_16860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N4T41_16890	COG0427	acetyl-CoA hydrolase
N4T41_16915	COG0659	secondary active sulfate transmembrane transporter activity
N4T41_16920	COG4221	oxidoreductase activity
N4T41_16930	COG0488	(ABC) transporter
N4T41_16995	COG0833	amino acid
N4T41_17040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N4T41_17045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N4T41_17060	COG2226	methyltransferase
N4T41_17110	COG0069	glutamate synthase activity
N4T41_17110	COG0067	glutamate synthase
N4T41_17110	COG0070	glutamate synthase
N4T41_17115	COG0493	'glutamate synthase
N4T41_17125	COG1704	LemA family
N4T41_17130	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N4T41_17150	COG3307	-O-antigen
N4T41_17170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N4T41_17185	COG0194	GDP metabolic process
N4T41_17235	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N4T41_17255	COG5380	lipid catabolic process
N4T41_17260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N4T41_17285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N4T41_17290	COG0277	FAD linked oxidase domain protein
N4T41_17305	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N4T41_17310	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T41_17335	COG4372	Transposase
N4T41_17345	COG1289	transmembrane transporter activity
N4T41_17355	COG0628	permease
N4T41_17360	COG1192	Involved in chromosome partitioning
N4T41_17390	COG0833	amino acid
N4T41_17395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N4T41_17400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N4T41_17410	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_17450	COG0583	DNA-binding transcription factor activity
N4T41_17470	COG1106	Psort location Cytoplasmic, score
N4T41_17505	COG0517	IMP dehydrogenase activity
N4T41_17510	COG1983	PspC domain protein
N4T41_17520	COG1960	acyl-CoA dehydrogenase activity
N4T41_17535	COG0408	coproporphyrinogen oxidase activity
N4T41_17555	COG0513	Belongs to the DEAD box helicase family
N4T41_17565	COG1127	ABC transporter
N4T41_17570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N4T41_17580	COG2854	intermembrane phospholipid transfer
N4T41_17590	COG0598	Magnesium transport protein CorA
N4T41_17600	COG0494	nUDIX hydrolase
N4T41_17605	COG1040	competence protein
N4T41_17610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N4T41_17630	COG1946	Acyl-CoA thioesterase
N4T41_17635	COG1301	dicarboxylic acid transport
N4T41_17650	COG1959	2 iron, 2 sulfur cluster binding
N4T41_17655	COG1017	nitric oxide dioxygenase activity
N4T41_17655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T41_17665	COG0433	COG0433 Predicted ATPase
N4T41_17670	COG0626	cystathionine gamma-synthase activity
N4T41_17825	COG1960	acyl-CoA dehydrogenase activity
N4T41_17830	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N4T41_17860	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
N4T41_17865	COG0339	signal peptide processing
N4T41_17870	COG0557	exoribonuclease II activity
N4T41_17915	COG0179	Fumarylacetoacetate (FAA) hydrolase
N4T41_17925	COG0697	spore germination
N4T41_17930	COG1295	ribonuclease BN
N4T41_17965	COG1702	phosphate starvation-inducible protein PhoH
N4T41_17975	COG0739	heme binding
N4T41_17975	COG1196	nuclear chromosome segregation
N4T41_17975	COG0741	lytic transglycosylase activity
N4T41_18005	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N4T41_18010	COG1183	phosphatidylcholine synthase activity
N4T41_18055	COG1960	acyl-CoA dehydrogenase activity
N4T41_18060	COG1309	transcriptional regulator
N4T41_18075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N4T41_18080	COG1960	acyl-CoA dehydrogenase activity
N4T41_18100	COG2969	positive regulation of protein catabolic process
N4T41_18110	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N4T41_18125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N4T41_18130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N4T41_18150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N4T41_18160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N4T41_18165	COG1408	metallophosphoesterase
N4T41_18175	COG2199	diguanylate cyclase activity
N4T41_18235	COG1607	acyl-coa hydrolase
N4T41_18265	COG2350	Protein conserved in bacteria
N4T41_18275	COG0613	PHP domain protein
N4T41_18280	COG3781	membrane
N4T41_18290	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N4T41_18295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N4T41_18305	COG1862	Preprotein translocase
N4T41_18365	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N4T41_18385	COG0726	polysaccharide deacetylase
N4T41_18390	COG0463	Glycosyl transferase, family 2
N4T41_18395	COG0438	transferase activity, transferring glycosyl groups
N4T41_18420	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_18480	COG1960	acyl-CoA dehydrogenase activity
N4T41_18485	COG1960	acyl-CoA dehydrogenase activity
N4T41_18495	COG2205	protein histidine kinase activity
N4T41_18500	COG0745	RESPONSE REGULATOR receiver
N4T41_18505	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N4T41_18520	COG0584	glycerophosphoryl diester phosphodiesterase
N4T41_18525	COG2096	Adenosyltransferase
N4T41_18530	COG4206	TonB-dependent receptor
N4T41_18575	COG0285	dihydrofolate synthase activity
N4T41_18595	COG0450	alkyl hydroperoxide reductase
N4T41_18610	COG0477	Major facilitator Superfamily
N4T41_18615	COG1272	protein, Hemolysin III
N4T41_18645	COG0183	Belongs to the thiolase family
N4T41_18650	COG2207	Transcriptional regulator
N4T41_18670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T41_18690	COG0183	Belongs to the thiolase family
N4T41_18700	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N4T41_18700	COG2885	chlorophyll binding
N4T41_18710	COG1690	Belongs to the RtcB family
N4T41_18715	COG0833	amino acid
N4T41_18725	COG2233	PERMEase
N4T41_18730	COG1217	gtp-binding protein TYPA
N4T41_18755	COG2094	Belongs to the DNA glycosylase MPG family
N4T41_18760	COG4772	TonB-dependent receptor
N4T41_18765	COG1902	pentaerythritol trinitrate reductase activity
N4T41_18780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T41_18785	COG0354	folic acid binding
N4T41_18795	COG3189	MarR family transcriptional regulator
N4T41_18800	COG2824	Alkylphosphonate utilization operon protein PhnA
N4T41_18805	COG3422	double-strand break repair
N4T41_18845	COG0840	transmembrane signaling receptor activity
N4T41_18865	COG5510	response to toxic substance
N4T41_18875	COG2832	Protein of unknown function (DUF454)
N4T41_18880	COG1376	ErfK ybiS ycfS ynhG family protein
N4T41_18920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N4T41_18930	COG1289	transmembrane transporter activity
N4T41_18935	COG2814	Major facilitator Superfamily
N4T41_18955	COG1115	amino acid carrier protein
N4T41_18960	COG1752	Esterase of the alpha-beta hydrolase superfamily
N4T41_18965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N4T41_18970	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
N4T41_19000	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N4T41_19010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N4T41_19015	COG1077	Cell shape determining protein MreB Mrl
N4T41_19020	COG1792	Involved in formation and maintenance of cell shape
N4T41_19025	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N4T41_19030	COG0424	maF-like protein
N4T41_19035	COG1530	ribonuclease E activity
N4T41_19045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T41_19055	COG0560	Phosphoserine phosphatase
N4T41_19065	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T41_19090	COG2207	Transcriptional regulator
N4T41_19110	COG0464	growth
N4T41_19135	COG2826	transposase and inactivated derivatives, IS30 family
N4T41_19190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N4T41_19200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N4T41_19215	COG0730	response to heat
N4T41_19225	COG1196	nuclear chromosome segregation
N4T41_19245	COG2223	nitrite transmembrane transporter activity
N4T41_19250	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
N4T41_19255	COG1877	trehalose-phosphatase activity
N4T41_19260	COG2226	methyltransferase
N4T41_19260	COG0596	Alpha beta hydrolase
N4T41_19260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N4T41_19275	COG4106	trans-aconitate 2-methyltransferase activity
N4T41_19290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N4T41_19295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N4T41_19300	COG0009	L-threonylcarbamoyladenylate synthase
N4T41_19305	COG3101	peptidyl-lysine hydroxylation
N4T41_19310	COG1399	metal-binding, possibly nucleic acid-binding protein
N4T41_19335	COG1652	LysM domain
N4T41_19340	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N4T41_19340	COG0351	phosphomethylpyrimidine kinase
N4T41_19340	COG0352	thiamine-phosphate diphosphorylase activity
N4T41_19350	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N4T41_19380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N4T41_19410	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N4T41_19425	COG0358	DNA primase activity
N4T41_19435	COG0564	pseudouridine synthase activity
N4T41_19485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T41_19515	COG3620	sequence-specific DNA binding
N4T41_19545	COG0305	Participates in initiation and elongation during chromosome replication
N4T41_19635	COG5410	chromosome segregation
N4T41_19765	COG3561	AntA/AntB antirepressor
N4T41_19775	COG0739	heme binding
N4T41_19855	COG0582	viral genome integration into host DNA
N4T41_19865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T41_19885	COG0583	DNA-binding transcription factor activity
N4T41_19890	COG0473	3-isopropylmalate dehydrogenase activity
N4T41_19900	COG0657	acetylesterase activity
N4T41_19910	COG1012	belongs to the aldehyde dehydrogenase family
N4T41_19930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N4T41_19930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N4T41_19945	COG1981	membrane
N4T41_19990	COG0456	acetyltransferase
N4T41_20000	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N4T41_20005	COG0492	ferredoxin-NADP+ reductase activity
N4T41_20010	COG1674	ftsk spoiiie
N4T41_20015	COG1280	lysine exporter protein (LysE YggA)
N4T41_20030	COG2894	cell division
N4T41_20045	COG0204	Acyl-transferase
N4T41_20050	COG2885	chlorophyll binding
N4T41_20055	COG0210	DNA helicase
N4T41_20065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T41_20080	COG0121	glutamine amidotransferase
N4T41_20100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N4T41_20105	COG0735	belongs to the Fur family
N4T41_20130	COG0420	3'-5' exonuclease activity
N4T41_20150	COG1090	epimerase
N4T41_20165	COG2050	protein possibly involved in aromatic compounds catabolism
N4T41_20175	COG2814	Major facilitator Superfamily
N4T41_20180	COG0405	Gamma-glutamyltransferase
N4T41_20250	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
N4T41_20260	COG0477	Major facilitator Superfamily
N4T41_20265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T41_20275	COG1595	DNA-templated transcription, initiation
N4T41_20330	COG0531	amino acid
N4T41_20360	COG1309	transcriptional regulator
N4T41_20365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N4T41_20370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N4T41_20380	COG1607	acyl-coa hydrolase
N4T41_20390	COG0523	cobalamin synthesis protein
N4T41_20400	COG4681	YaeQ
N4T41_20410	COG0726	polysaccharide deacetylase
N4T41_20410	COG1649	PFAM Uncharacterised BCR, COG1649
N4T41_20415	COG1215	transferase activity, transferring glycosyl groups
N4T41_20425	COG1024	Enoyl-CoA hydratase
N4T41_20440	COG1414	Transcriptional regulator
N4T41_20460	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_20475	COG2271	Major facilitator Superfamily
N4T41_20490	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_20505	COG0028	Belongs to the TPP enzyme family
N4T41_20515	COG0477	Major facilitator Superfamily
N4T41_20520	COG0242	peptide deformylase activity
N4T41_20525	COG2066	Belongs to the glutaminase family
N4T41_20530	COG2207	Transcriptional regulator
N4T41_20535	COG2223	nitrite transmembrane transporter activity
N4T41_20550	COG0583	DNA-binding transcription factor activity
N4T41_20555	COG1028	Short-chain dehydrogenase reductase Sdr
N4T41_20560	COG2271	Major facilitator Superfamily
N4T41_20565	COG3959	Transketolase, thiamine diphosphate binding domain
N4T41_20570	COG3958	Transketolase
N4T41_20580	COG0306	phosphate transporter
N4T41_20600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N4T41_20645	COG4181	ATPase activity
N4T41_20680	COG0583	DNA-binding transcription factor activity
N4T41_20695	COG1773	rubredoxin
N4T41_20750	COG2851	Citrate transporter
N4T41_20755	COG1253	flavin adenine dinucleotide binding
N4T41_20800	COG0804	urea catabolic process
N4T41_20810	COG0830	nickel cation binding
N4T41_20825	COG0742	ribosomal rna small subunit methyltransferase
N4T41_20830	COG0768	penicillin binding
N4T41_20855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N4T41_20860	COG2878	Part of a membrane complex involved in electron transport
N4T41_20865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N4T41_20875	COG3384	dioxygenase
N4T41_20905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N4T41_21090	COG5410	chromosome segregation
N4T41_21200	COG1196	nuclear chromosome segregation
N4T41_21200	COG0739	heme binding
N4T41_21200	COG0741	lytic transglycosylase activity
N4T41_21245	COG2194	sulfuric ester hydrolase activity
N4T41_21285	COG0006	proline dipeptidase activity
N4T41_21290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T41_21295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T41_21315	COG1279	arginine transmembrane transporter activity
N4T41_21320	COG0583	DNA-binding transcription factor activity
N4T41_21375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T41_21380	COG1388	LysM domain
N4T41_21380	COG0741	lytic transglycosylase activity
N4T41_21380	COG0741	lytic transglycosylase activity
N4T41_21380	COG1388	LysM domain
N4T41_21390	COG4174	ABC transporter (Permease)
N4T41_21395	COG4239	(ABC) transporter, permease
N4T41_21400	COG4172	Belongs to the ABC transporter superfamily
N4T41_21420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T41_21440	COG0446	pyridine nucleotide-disulphide oxidoreductase
N4T41_21440	COG1902	pentaerythritol trinitrate reductase activity
N4T41_21450	COG0582	viral genome integration into host DNA
N4T41_21490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T41_21505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N4T41_21550	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N4T41_21560	COG0300	oxidoreductase activity
N4T41_21570	COG1309	transcriptional regulator
N4T41_21575	COG1741	Belongs to the pirin family
N4T41_21590	COG2072	flavoprotein involved in K transport
N4T41_21600	COG2252	PERMEase
N4T41_21605	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N4T41_21610	COG3038	cytochrome b561
N4T41_21620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N4T41_21630	COG0527	aspartate kinase activity
N4T41_21775	COG0739	heme binding
N4T41_21855	COG0582	viral genome integration into host DNA
N4T41_21890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T41_21920	COG3620	sequence-specific DNA binding
N4T41_21950	COG0305	Participates in initiation and elongation during chromosome replication
N4T41_22040	COG5410	chromosome segregation
N4T41_22170	COG3561	AntA/AntB antirepressor