locus-tag	class	description
PF555_00010	COG0592	DNA-directed DNA polymerase activity
PF555_00020	COG0187	DNA topoisomerase II activity
PF555_00030	COG0586	Pfam SNARE associated Golgi protein
PF555_00035	COG0488	(ABC) transporter
PF555_00060	COG0596	Alpha beta hydrolase
PF555_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PF555_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PF555_00110	COG0733	neurotransmitter:sodium symporter activity
PF555_00145	COG0583	DNA-binding transcription factor activity
PF555_00150	COG2233	PERMEase
PF555_00180	COG1192	Involved in chromosome partitioning
PF555_00190	COG0271	Belongs to the BolA IbaG family
PF555_00210	COG4372	Transposase
PF555_00220	COG2963	transposase activity
PF555_00250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PF555_00250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
PF555_00250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF555_00250	COG3321	synthase
PF555_00255	COG1960	acyl-CoA dehydrogenase activity
PF555_00265	COG2197	response regulator
PF555_00275	COG3916	Acyl-homoserine-lactone synthase
PF555_00280	COG0477	Major facilitator Superfamily
PF555_00285	COG1024	Enoyl-CoA hydratase
PF555_00290	COG1024	Enoyl-CoA hydratase
PF555_00295	COG1960	acyl-CoA dehydrogenase activity
PF555_00300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PF555_00340	COG0583	DNA-binding transcription factor activity
PF555_00360	COG0657	acetylesterase activity
PF555_00365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PF555_00405	COG1047	Peptidyl-prolyl cis-trans
PF555_00415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PF555_00420	COG0196	riboflavin kinase activity
PF555_00430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PF555_00435	COG1309	transcriptional regulator
PF555_00440	COG1116	anion transmembrane transporter activity
PF555_00445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PF555_00450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF555_00455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PF555_00460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PF555_00480	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_00485	COG0546	phosphoglycolate phosphatase activity
PF555_00545	COG3023	N-Acetylmuramoyl-L-alanine amidase
PF555_00550	COG0728	peptidoglycan biosynthetic process
PF555_00580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PF555_00610	COG0438	transferase activity, transferring glycosyl groups
PF555_00630	COG1216	Glycosyl transferase, family 2
PF555_00635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PF555_00640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PF555_00655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PF555_00660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PF555_00670	COG2186	Transcriptional regulator
PF555_00680	COG0277	FAD linked oxidase domain protein
PF555_00685	COG1448	Aminotransferase
PF555_00695	COG1802	Transcriptional regulator
PF555_00710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PF555_00780	COG0564	pseudouridine synthase activity
PF555_00820	COG0251	oxidation-reduction process
PF555_00855	COG0010	Belongs to the arginase family
PF555_00870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PF555_00875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PF555_00885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PF555_00890	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PF555_00975	COG0534	Mate efflux family protein
PF555_00980	COG0436	Aminotransferase
PF555_00985	COG2733	membrane
PF555_01000	COG2918	glutathione biosynthetic process
PF555_01015	COG3179	chitinase
PF555_01030	COG3150	esterase
PF555_01040	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
PF555_01050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PF555_01060	COG2233	PERMEase
PF555_01065	COG2351	hydroxyisourate hydrolase activity
PF555_01100	COG3706	GGDEF domain
PF555_01115	COG1393	Belongs to the ArsC family
PF555_01120	COG0708	Exodeoxyribonuclease III
PF555_01145	COG0189	ligase activity
PF555_01165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PF555_01175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PF555_01190	COG4942	peptidase
PF555_01200	COG0508	dehydrogenase complex catalyzes the overall conversion of
PF555_01210	COG2119	membrane
PF555_01215	COG4774	siderophore transport
PF555_01220	COG0426	domain, Protein
PF555_01220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PF555_01245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PF555_01270	COG1902	pentaerythritol trinitrate reductase activity
PF555_01275	COG1519	Transferase
PF555_01280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PF555_01285	COG0668	transmembrane transport
PF555_01295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PF555_01300	COG1335	isochorismatase
PF555_01305	COG1522	sequence-specific DNA binding
PF555_01330	COG0784	Response regulator, receiver
PF555_01330	COG2198	Histidine kinase
PF555_01330	COG2205	protein histidine kinase activity
PF555_01335	COG3162	membrane
PF555_01340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PF555_01350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PF555_01370	COG1309	transcriptional regulator
PF555_01390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PF555_01390	COG0352	thiamine-phosphate diphosphorylase activity
PF555_01390	COG0351	phosphomethylpyrimidine kinase
PF555_01400	COG2814	Major facilitator Superfamily
PF555_01415	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PF555_01425	COG1113	amino acid transport
PF555_01435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PF555_01440	COG1012	belongs to the aldehyde dehydrogenase family
PF555_01450	COG1335	isochorismatase
PF555_01485	COG2814	Major facilitator Superfamily
PF555_01490	COG0583	DNA-binding transcription factor activity
PF555_01510	COG0667	Aldo Keto reductase
PF555_01540	COG1733	regulation of RNA biosynthetic process
PF555_01545	COG2249	NAD(P)H dehydrogenase (quinone) activity
PF555_01605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PF555_01655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PF555_01685	COG0427	acetyl-CoA hydrolase
PF555_01710	COG0659	secondary active sulfate transmembrane transporter activity
PF555_01715	COG4221	oxidoreductase activity
PF555_01725	COG0488	(ABC) transporter
PF555_01790	COG0833	amino acid
PF555_01835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PF555_01840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PF555_01855	COG2226	methyltransferase
PF555_01905	COG0070	glutamate synthase
PF555_01905	COG0069	glutamate synthase activity
PF555_01905	COG0067	glutamate synthase
PF555_01910	COG0493	'glutamate synthase
PF555_01920	COG1704	LemA family
PF555_01925	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PF555_01945	COG3307	-O-antigen
PF555_01965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PF555_01980	COG0194	GDP metabolic process
PF555_02030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PF555_02050	COG5380	lipid catabolic process
PF555_02055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PF555_02080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PF555_02085	COG0277	FAD linked oxidase domain protein
PF555_02100	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PF555_02105	COG2249	NAD(P)H dehydrogenase (quinone) activity
PF555_02120	COG1289	transmembrane transporter activity
PF555_02130	COG0628	permease
PF555_02135	COG1192	Involved in chromosome partitioning
PF555_02165	COG0833	amino acid
PF555_02170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PF555_02175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PF555_02185	COG1012	belongs to the aldehyde dehydrogenase family
PF555_02225	COG0583	DNA-binding transcription factor activity
PF555_02285	COG0517	IMP dehydrogenase activity
PF555_02290	COG1983	PspC domain protein
PF555_02300	COG1960	acyl-CoA dehydrogenase activity
PF555_02315	COG0408	coproporphyrinogen oxidase activity
PF555_02335	COG0513	Belongs to the DEAD box helicase family
PF555_02345	COG1127	ABC transporter
PF555_02350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PF555_02360	COG2854	intermembrane phospholipid transfer
PF555_02370	COG0598	Magnesium transport protein CorA
PF555_02380	COG0494	nUDIX hydrolase
PF555_02385	COG1040	competence protein
PF555_02390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PF555_02410	COG1946	Acyl-CoA thioesterase
PF555_02415	COG1301	dicarboxylic acid transport
PF555_02430	COG1959	2 iron, 2 sulfur cluster binding
PF555_02435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PF555_02435	COG1017	nitric oxide dioxygenase activity
PF555_02445	COG0433	COG0433 Predicted ATPase
PF555_02450	COG0626	cystathionine gamma-synthase activity
PF555_02605	COG1960	acyl-CoA dehydrogenase activity
PF555_02610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PF555_02640	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PF555_02645	COG0339	signal peptide processing
PF555_02650	COG0557	exoribonuclease II activity
PF555_02695	COG0179	Fumarylacetoacetate (FAA) hydrolase
PF555_02700	COG2169	Transcriptional regulator
PF555_02705	COG0697	spore germination
PF555_02710	COG1295	ribonuclease BN
PF555_02745	COG1702	phosphate starvation-inducible protein PhoH
PF555_02755	COG1196	nuclear chromosome segregation
PF555_02755	COG0741	lytic transglycosylase activity
PF555_02755	COG0739	heme binding
PF555_02785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PF555_02790	COG1183	phosphatidylcholine synthase activity
PF555_02835	COG1960	acyl-CoA dehydrogenase activity
PF555_02840	COG1309	transcriptional regulator
PF555_02855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PF555_02860	COG1960	acyl-CoA dehydrogenase activity
PF555_02880	COG2969	positive regulation of protein catabolic process
PF555_02890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PF555_02900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PF555_02905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PF555_02910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PF555_02930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PF555_02940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PF555_02945	COG1408	metallophosphoesterase
PF555_02955	COG2199	diguanylate cyclase activity
PF555_03015	COG1607	acyl-coa hydrolase
PF555_03045	COG2350	Protein conserved in bacteria
PF555_03055	COG0613	PHP domain protein
PF555_03060	COG3781	membrane
PF555_03070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PF555_03075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PF555_03085	COG1862	Preprotein translocase
PF555_03115	COG2205	protein histidine kinase activity
PF555_03120	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PF555_03140	COG0726	polysaccharide deacetylase
PF555_03145	COG0463	Glycosyl transferase, family 2
PF555_03150	COG0438	transferase activity, transferring glycosyl groups
PF555_03215	COG1960	acyl-CoA dehydrogenase activity
PF555_03220	COG1960	acyl-CoA dehydrogenase activity
PF555_03230	COG2205	protein histidine kinase activity
PF555_03235	COG0745	RESPONSE REGULATOR receiver
PF555_03240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PF555_03260	COG2096	Adenosyltransferase
PF555_03310	COG0285	dihydrofolate synthase activity
PF555_03330	COG0450	alkyl hydroperoxide reductase
PF555_03345	COG0477	Major facilitator Superfamily
PF555_03350	COG1272	protein, Hemolysin III
PF555_03380	COG0183	Belongs to the thiolase family
PF555_03385	COG2207	Transcriptional regulator
PF555_03405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PF555_03425	COG0183	Belongs to the thiolase family
PF555_03435	COG2885	chlorophyll binding
PF555_03435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PF555_03445	COG1690	Belongs to the RtcB family
PF555_03450	COG0833	amino acid
PF555_03460	COG2233	PERMEase
PF555_03465	COG1217	gtp-binding protein TYPA
PF555_03490	COG2094	Belongs to the DNA glycosylase MPG family
PF555_03495	COG4772	TonB-dependent receptor
PF555_03500	COG1902	pentaerythritol trinitrate reductase activity
PF555_03515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PF555_03520	COG0354	folic acid binding
PF555_03530	COG3189	MarR family transcriptional regulator
PF555_03535	COG2824	Alkylphosphonate utilization operon protein PhnA
PF555_03540	COG3422	double-strand break repair
PF555_03580	COG0840	transmembrane signaling receptor activity
PF555_03600	COG5510	response to toxic substance
PF555_03610	COG2832	Protein of unknown function (DUF454)
PF555_03615	COG1376	ErfK ybiS ycfS ynhG family protein
PF555_03655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PF555_03665	COG1289	transmembrane transporter activity
PF555_03670	COG2814	Major facilitator Superfamily
PF555_03690	COG1115	amino acid carrier protein
PF555_03695	COG1752	Esterase of the alpha-beta hydrolase superfamily
PF555_03700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PF555_03705	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
PF555_03730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PF555_03740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PF555_03745	COG1077	Cell shape determining protein MreB Mrl
PF555_03750	COG1792	Involved in formation and maintenance of cell shape
PF555_03755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PF555_03760	COG0424	maF-like protein
PF555_03765	COG1530	ribonuclease E activity
PF555_03775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF555_03785	COG0560	Phosphoserine phosphatase
PF555_03795	COG2249	NAD(P)H dehydrogenase (quinone) activity
PF555_03820	COG2207	Transcriptional regulator
PF555_03865	COG1113	amino acid transport
PF555_03870	COG2828	Protein conserved in bacteria
PF555_03875	COG0142	geranyltranstransferase activity
PF555_03880	COG2315	Protein conserved in bacteria
PF555_03895	COG1752	Esterase of the alpha-beta hydrolase superfamily
PF555_03910	COG2963	transposase activity
PF555_03920	COG4372	Transposase
PF555_03935	COG4372	Transposase
PF555_03945	COG2963	transposase activity
PF555_03955	COG0745	RESPONSE REGULATOR receiver
PF555_03960	COG0642	Histidine kinase
PF555_03970	COG0004	ammonium transporteR
PF555_03975	COG0583	DNA-binding transcription factor activity
PF555_03990	COG2226	methyltransferase
PF555_03995	COG0525	valine-tRNA ligase activity
PF555_04005	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_04015	COG0393	Putative heavy-metal-binding
PF555_04020	COG0393	Putative heavy-metal-binding
PF555_04025	COG1538	Outer membrane efflux protein
PF555_04035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PF555_04040	COG0671	phosphoesterase, PA-phosphatase related
PF555_04070	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PF555_04085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PF555_04085	COG1648	precorrin-2 dehydrogenase activity
PF555_04090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PF555_04095	COG1733	regulation of RNA biosynthetic process
PF555_04105	COG0531	amino acid
PF555_04120	COG0321	lipoyl(octanoyl) transferase activity
PF555_04125	COG2921	Belongs to the UPF0250 family
PF555_04165	COG2009	succinate dehydrogenase
PF555_04170	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PF555_04175	COG1053	succinate dehydrogenase
PF555_04180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PF555_04205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PF555_04225	COG2354	Protein conserved in bacteria
PF555_04230	COG2321	neutral zinc metallopeptidase
PF555_04250	COG2843	Capsule synthesis protein
PF555_04265	COG0589	response to stress
PF555_04285	COG0505	Belongs to the CarA family
PF555_04310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PF555_04315	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PF555_04365	COG0477	Major facilitator Superfamily
PF555_04370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PF555_04385	COG1597	lipid kinase activity
PF555_04390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PF555_04415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF555_04420	COG0584	glycerophosphoryl diester phosphodiesterase
PF555_04440	COG0741	lytic transglycosylase activity
PF555_04460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PF555_04485	COG3811	Belongs to the UPF0386 family
PF555_04505	COG0778	Nitroreductase
PF555_04520	COG1929	Belongs to the glycerate kinase type-1 family
PF555_04525	COG0243	molybdopterin cofactor binding
PF555_04530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PF555_04535	COG3339	Conserved Protein
PF555_04545	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PF555_04560	COG1113	amino acid transport
PF555_04570	COG0019	diaminopimelate decarboxylase activity
PF555_04580	COG1280	lysine exporter protein (LysE YggA)
PF555_04585	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PF555_04615	COG0463	Glycosyl transferase, family 2
PF555_04635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PF555_04670	COG4591	ABC-type transport system involved in lipoprotein release permease component
PF555_04675	COG1136	(ABC) transporter
PF555_04680	COG0658	competence protein
PF555_04680	COG2333	competence protein COMEC
PF555_04690	COG0616	signal peptide processing
PF555_04690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PF555_04695	COG0596	Alpha beta hydrolase
PF555_04700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PF555_04710	COG0628	permease
PF555_04730	COG4372	Transposase
PF555_04740	COG2963	transposase activity
PF555_04810	COG0582	viral genome integration into host DNA
PF555_04825	COG0174	glutamine synthetase
PF555_04835	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PF555_04870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PF555_04875	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PF555_04880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PF555_04900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PF555_04905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PF555_04910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PF555_04925	COG1960	acyl-CoA dehydrogenase activity
PF555_04930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PF555_04935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PF555_04945	COG2223	nitrite transmembrane transporter activity
PF555_04955	COG0024	Methionine aminopeptidase
PF555_04960	COG0052	Belongs to the universal ribosomal protein uS2 family
PF555_04975	COG2207	Transcriptional regulator
PF555_05000	COG2951	lytic endotransglycosylase activity
PF555_05005	COG0772	Belongs to the SEDS family
PF555_05020	COG0842	Transport permease protein
PF555_05025	COG1131	(ABC) transporter
PF555_05070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PF555_05085	COG4215	(ABC) transporter
PF555_05090	COG4160	amino acid transport
PF555_05095	COG4598	ABC transporter
PF555_05105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PF555_05110	COG0826	peptidase U32
PF555_05115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF555_05120	COG0384	phenazine biosynthesis protein PhzF
PF555_05130	COG1720	tRNA m6t6A37 methyltransferase activity
PF555_05165	COG0642	Histidine kinase
PF555_05175	COG0494	nUDIX hydrolase
PF555_05185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PF555_05190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PF555_05195	COG3139	Protein of unknown function (DUF1315)
PF555_05200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PF555_05205	COG1301	dicarboxylic acid transport
PF555_05210	COG1960	acyl-CoA dehydrogenase activity
PF555_05215	COG2819	hydrolase of the alpha beta superfamily
PF555_05225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PF555_05235	COG2195	Cleaves the N-terminal amino acid of tripeptides
PF555_05240	COG1234	tRNA 3'-trailer cleavage
PF555_05270	COG2363	Small membrane protein
PF555_05295	COG0513	Belongs to the DEAD box helicase family
PF555_05305	COG0778	Nitroreductase
PF555_05335	COG1286	toxin biosynthetic process
PF555_05360	COG4783	chaperone-mediated protein folding
PF555_05365	COG1610	YqeY-like protein
PF555_05395	COG0515	serine threonine protein kinase
PF555_05395	COG2815	serine threonine protein kinase
PF555_05420	COG2831	hemolysin activation secretion protein
PF555_05425	COG3210	domain, Protein
PF555_05425	COG3210	domain, Protein
PF555_05495	COG0477	Major facilitator Superfamily
PF555_05500	COG1051	belongs to the nudix hydrolase family
PF555_05530	COG2995	paraquat-inducible protein a
PF555_05535	COG3008	intermembrane lipid transfer
PF555_05535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PF555_05545	COG1794	racemase activity, acting on amino acids and derivatives
PF555_05580	COG1301	dicarboxylic acid transport
PF555_05590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF555_05595	COG2011	ABC-type metal ion transport system permease component
PF555_05600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PF555_05605	COG1464	Belongs to the NlpA lipoprotein family
PF555_05610	COG0151	Belongs to the GarS family
PF555_05615	COG0138	bifunctional purine biosynthesis protein purh
PF555_05620	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PF555_05650	COG2308	Evidence 4 Homologs of previously reported genes of
PF555_05660	COG1305	Transglutaminase-like
PF555_05670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PF555_05675	COG0305	Participates in initiation and elongation during chromosome replication
PF555_05700	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PF555_05710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PF555_05715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PF555_05740	COG1649	PFAM Uncharacterised BCR, COG1649
PF555_05740	COG0726	polysaccharide deacetylase
PF555_05745	COG1215	transferase activity, transferring glycosyl groups
PF555_05750	COG3658	cytochrome
PF555_05760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF555_05775	COG0583	DNA-binding transcription factor activity
PF555_05805	COG1960	acyl-CoA dehydrogenase activity
PF555_05810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PF555_05815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PF555_05830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PF555_05840	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PF555_05845	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PF555_05855	COG2205	protein histidine kinase activity
PF555_05860	COG0745	RESPONSE REGULATOR receiver
PF555_05865	COG0174	glutamine synthetase
PF555_05870	COG4372	Transposase
PF555_05880	COG2963	transposase activity
PF555_05900	COG0729	surface antigen
PF555_05925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PF555_05930	COG2814	Major facilitator Superfamily
PF555_05945	COG0583	DNA-binding transcription factor activity
PF555_05960	COG1187	pseudouridine synthase activity
PF555_05980	COG0802	atpase or kinase
PF555_05985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PF555_05995	COG1923	regulation of RNA biosynthetic process
PF555_06000	COG0697	spore germination
PF555_06015	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PF555_06025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PF555_06030	COG0519	Catalyzes the synthesis of GMP from XMP
PF555_06030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PF555_06035	COG4302	ethanolamine ammonia-lyase activity
PF555_06040	COG4303	Ethanolamine ammonia lyase large subunit
PF555_06045	COG0531	amino acid
PF555_06065	COG1454	alcohol dehydrogenase
PF555_06070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PF555_06080	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PF555_06100	COG0308	aminopeptidase N
PF555_06140	COG1605	Chorismate mutase
PF555_06155	COG1309	transcriptional regulator
PF555_06165	COG0668	transmembrane transport
PF555_06195	COG4773	Receptor
PF555_06215	COG0488	(ABC) transporter
PF555_06220	COG0589	response to stress
PF555_06245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PF555_06255	COG3135	benzoate transporter
PF555_06260	COG1522	sequence-specific DNA binding
PF555_06270	COG2963	transposase activity
PF555_06280	COG4372	Transposase
PF555_06290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PF555_06295	COG0583	DNA-binding transcription factor activity
PF555_06305	COG0183	Belongs to the thiolase family
PF555_06315	COG2030	dehydratase
PF555_06320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PF555_06335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PF555_06350	COG0824	Thioesterase
PF555_06355	COG1454	alcohol dehydrogenase
PF555_06365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PF555_06385	COG0069	glutamate synthase activity
PF555_06405	COG2814	Major facilitator Superfamily
PF555_06420	COG0511	ligase activity, forming carbon-carbon bonds
PF555_06435	COG1116	anion transmembrane transporter activity
PF555_06435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PF555_06440	COG0745	RESPONSE REGULATOR receiver
PF555_06450	COG2146	nitrite reductase [NAD(P)H] activity
PF555_06450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PF555_06455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PF555_06460	COG0243	molybdopterin cofactor binding
PF555_06470	COG0243	molybdopterin cofactor binding
PF555_06475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PF555_06490	COG0521	Mo-molybdopterin cofactor biosynthetic process
PF555_06490	COG0315	cyclic pyranopterin monophosphate synthase activity
PF555_06495	COG0303	'Molybdopterin
PF555_06505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF555_06510	COG0697	spore germination
PF555_06530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PF555_06535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PF555_06605	COG2204	response regulator
PF555_06610	COG3852	Histidine kinase
PF555_06635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PF555_06640	COG0575	Belongs to the CDS family
PF555_06675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PF555_06690	COG2137	regulation of response to DNA damage stimulus
PF555_06700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PF555_06705	COG1011	Hydrolase
PF555_06730	COG1522	sequence-specific DNA binding
PF555_06740	COG1113	amino acid transport
PF555_06765	COG4372	Transposase
PF555_06775	COG2963	transposase activity
PF555_06780	COG0659	secondary active sulfate transmembrane transporter activity
PF555_06785	COG2135	peptidase activity
PF555_06800	COG2963	transposase activity
PF555_06810	COG4372	Transposase
PF555_06820	COG3300	MHYT domain
PF555_06820	COG5001	Diguanylate cyclase
PF555_06835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PF555_06835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PF555_06835	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PF555_06840	COG1105	Belongs to the carbohydrate kinase PfkB family
PF555_06845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PF555_06845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF555_06875	COG0024	Methionine aminopeptidase
PF555_06880	COG0583	DNA-binding transcription factor activity
PF555_06890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PF555_06895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PF555_06900	COG0517	IMP dehydrogenase activity
PF555_06900	COG0516	GMP reductase activity
PF555_06925	COG0552	protein localization to endoplasmic reticulum
PF555_06935	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
PF555_06945	COG4890	Cyd operon protein YbgT
PF555_06950	COG1294	oxidase, subunit
PF555_06965	COG4372	Transposase
PF555_06975	COG2963	transposase activity
PF555_06980	COG1585	Membrane protein implicated in regulation of membrane protease activity
PF555_06990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PF555_06995	COG4774	siderophore transport
PF555_07010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PF555_07015	COG0569	domain protein
PF555_07020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PF555_07050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PF555_07055	COG0542	response to heat
PF555_07080	COG1902	pentaerythritol trinitrate reductase activity
PF555_07080	COG0446	pyridine nucleotide-disulphide oxidoreductase
PF555_07125	COG2323	membrane
PF555_07130	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PF555_07140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PF555_07145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PF555_07150	COG0183	Belongs to the thiolase family
PF555_07155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PF555_07160	COG0596	Alpha beta hydrolase
PF555_07165	COG2271	Major facilitator Superfamily
PF555_07170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PF555_07175	COG3485	protocatechuate 3,4-dioxygenase
PF555_07180	COG3485	protocatechuate 3,4-dioxygenase
PF555_07185	COG0710	3-dehydroquinate dehydratase activity
PF555_07190	COG3420	alginic acid biosynthetic process
PF555_07195	COG3659	wide pore channel activity
PF555_07200	COG4993	Dehydrogenase
PF555_07210	COG2391	methyltransferase activity
PF555_07225	COG1414	Transcriptional regulator
PF555_07230	COG0583	DNA-binding transcription factor activity
PF555_07235	COG1960	acyl-CoA dehydrogenase activity
PF555_07260	COG2814	Major facilitator Superfamily
PF555_07270	COG0154	amidase activity
PF555_07290	COG4638	Rieske (2fe-2S)
PF555_07300	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_07310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PF555_07320	COG3733	amine oxidase
PF555_07330	COG1012	belongs to the aldehyde dehydrogenase family
PF555_07340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PF555_07345	COG0183	Belongs to the thiolase family
PF555_07350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PF555_07355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PF555_07365	COG4829	muconolactone delta-isomerase
PF555_07370	COG4948	Mandelate Racemase Muconate Lactonizing
PF555_07375	COG0583	DNA-binding transcription factor activity
PF555_07385	COG2186	Transcriptional regulator
PF555_07405	COG1012	belongs to the aldehyde dehydrogenase family
PF555_07420	COG1902	pentaerythritol trinitrate reductase activity
PF555_07420	COG0446	pyridine nucleotide-disulphide oxidoreductase
PF555_07460	COG1309	transcriptional regulator
PF555_07470	COG1335	isochorismatase
PF555_07475	COG0583	DNA-binding transcription factor activity
PF555_07485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PF555_07485	COG0475	glutathione-regulated potassium exporter activity
PF555_07495	COG1473	amidohydrolase
PF555_07510	COG4191	Histidine kinase
PF555_07545	COG2188	Transcriptional regulator
PF555_07560	COG0583	DNA-binding transcription factor activity
PF555_07585	COG1566	PFAM secretion protein HlyD family protein
PF555_07600	COG1012	belongs to the aldehyde dehydrogenase family
PF555_07605	COG0129	dihydroxy-acid dehydratase activity
PF555_07615	COG0583	DNA-binding transcription factor activity
PF555_07620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PF555_07630	COG2084	Dehydrogenase
PF555_07635	COG2207	Transcriptional regulator
PF555_07650	COG1064	alcohol dehydrogenase
PF555_07660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF555_07665	COG1120	ATPase activity
PF555_07685	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PF555_07740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PF555_07775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PF555_07810	COG0477	Major facilitator Superfamily
PF555_07820	COG2963	transposase activity
PF555_07830	COG4372	Transposase
PF555_07845	COG1414	Transcriptional regulator
PF555_07900	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PF555_07910	COG0753	catalase activity
PF555_07930	COG4372	Transposase
PF555_07940	COG2963	transposase activity
PF555_08005	COG1535	isochorismatase
PF555_08005	COG3433	isochorismatase activity
PF555_08010	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_08015	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PF555_08020	COG4149	molybdate abc transporter
PF555_08025	COG0725	ABC transporter, periplasmic molybdate-binding protein
PF555_08035	COG4638	Rieske (2fe-2S)
PF555_08040	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PF555_08045	COG0543	2 iron, 2 sulfur cluster binding
PF555_08045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PF555_08060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PF555_08070	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_08085	COG2207	Transcriptional regulator
PF555_08090	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_08095	COG2610	gluconate transmembrane transporter activity
PF555_08105	COG1309	transcriptional regulator
PF555_08125	COG0583	DNA-binding transcription factor activity
PF555_08140	COG2031	fatty acid transporter
PF555_08145	COG0183	Belongs to the thiolase family
PF555_08150	COG0583	DNA-binding transcription factor activity
PF555_08155	COG0583	DNA-binding transcription factor activity
PF555_08170	COG1027	Aspartate ammonia-lyase
PF555_08180	COG0477	Major facilitator Superfamily
PF555_08205	COG4521	taurine ABC transporter
PF555_08220	COG2188	Transcriptional regulator
PF555_08230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PF555_08235	COG1733	regulation of RNA biosynthetic process
PF555_08240	COG3708	Transcriptional regulator
PF555_08240	COG2207	Transcriptional regulator
PF555_08255	COG0730	response to heat
PF555_08270	COG3453	Protein conserved in bacteria
PF555_08270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF555_08280	COG3781	membrane
PF555_08285	COG1063	alcohol dehydrogenase
PF555_08295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PF555_08300	COG0508	dehydrogenase complex catalyzes the overall conversion of
PF555_08305	COG0022	dehydrogenase e1 component
PF555_08310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PF555_08315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PF555_08330	COG3706	GGDEF domain
PF555_08335	COG4372	Transposase
PF555_08345	COG2963	transposase activity
PF555_08360	COG0133	tryptophan synthase activity
PF555_08370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PF555_08405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PF555_08430	COG2226	methyltransferase
PF555_08470	COG4372	Transposase
PF555_08480	COG2963	transposase activity
PF555_08500	COG0842	Transport permease protein
PF555_08505	COG0842	Transport permease protein
PF555_08510	COG1131	(ABC) transporter
PF555_08525	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PF555_08530	COG4773	Receptor
PF555_08550	COG0730	response to heat
PF555_08555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PF555_08575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PF555_08590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PF555_08620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PF555_08630	COG4264	IucA IucC family
PF555_08635	COG4264	IucA IucC family
PF555_08655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PF555_08670	COG1960	acyl-CoA dehydrogenase activity
PF555_08675	COG1960	acyl-CoA dehydrogenase activity
PF555_08680	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PF555_08685	COG2207	Transcriptional regulator
PF555_08690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PF555_08695	COG0776	regulation of translation
PF555_08720	COG0822	iron-sulfur transferase activity
PF555_08725	COG0316	Belongs to the HesB IscA family
PF555_08745	COG2963	transposase activity
PF555_08755	COG4372	Transposase
PF555_08770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PF555_08790	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PF555_08795	COG0702	epimerase
PF555_08830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PF555_08840	COG0339	signal peptide processing
PF555_08890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PF555_08895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PF555_08925	COG0776	regulation of translation
PF555_08990	COG0084	hydrolase, TatD family'
PF555_09010	COG1663	tetraacyldisaccharide 4'-kinase activity
PF555_09015	COG1132	(ABC) transporter
PF555_09025	COG0811	peptide transport
PF555_09030	COG1475	DNA binding
PF555_09035	COG1192	Involved in chromosome partitioning
PF555_09045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PF555_09060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PF555_09065	COG0191	fructose-bisphosphate aldolase activity
PF555_09085	COG0424	maF-like protein
PF555_09090	COG2850	peptidyl-arginine hydroxylation
PF555_09100	COG0640	Transcriptional regulator
PF555_09110	COG3619	membrane
PF555_09115	COG3122	Protein conserved in bacteria
PF555_09120	COG1132	(ABC) transporter
PF555_09140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PF555_09145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PF555_09155	COG0506	proline dehydrogenase activity
PF555_09155	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PF555_09155	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PF555_09160	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PF555_09175	COG3698	Phosphodiester glycosidase
PF555_09185	COG2353	YceI-like domain
PF555_09195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PF555_09225	COG4372	Transposase
PF555_09235	COG2963	transposase activity
PF555_09265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PF555_09265	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PF555_09290	COG3539	Fimbrial protein
PF555_09295	COG3121	Chaperone
PF555_09325	COG2963	transposase activity
PF555_09335	COG4372	Transposase
PF555_09350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PF555_09360	COG0583	DNA-binding transcription factor activity
PF555_09380	COG1309	transcriptional regulator
PF555_09395	COG1522	sequence-specific DNA binding
PF555_09405	COG1126	abc transporter atp-binding protein
PF555_09410	COG0765	amino acid transport
PF555_09415	COG0765	amino acid transport
PF555_09445	COG1464	Belongs to the NlpA lipoprotein family
PF555_09455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PF555_09460	COG2011	ABC-type metal ion transport system permease component
PF555_09465	COG0012	GTP binding
PF555_09490	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PF555_09525	COG4372	Transposase
PF555_09535	COG2963	transposase activity
PF555_09550	COG0386	Belongs to the glutathione peroxidase family
PF555_09560	COG0436	Aminotransferase
PF555_09605	COG3634	alkyl hydroperoxide reductase activity
PF555_09620	COG0583	DNA-binding transcription factor activity
PF555_09625	COG0798	PFAM Bile acid sodium symporter
PF555_09630	COG0640	Transcriptional regulator
PF555_09645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PF555_09655	COG0583	DNA-binding transcription factor activity
PF555_09665	COG1953	Uracil, thiamine, allantoin
PF555_09675	COG2175	clavaminate synthase activity
PF555_09680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PF555_09685	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PF555_09690	COG4521	taurine ABC transporter
PF555_09715	COG0477	Major facilitator Superfamily
PF555_09735	COG1271	oxidase subunit
PF555_09740	COG1294	oxidase, subunit
PF555_09750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF555_09770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PF555_09790	COG3052	prosthetic group binding
PF555_09795	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PF555_09805	COG0583	DNA-binding transcription factor activity
PF555_09815	COG2814	Major facilitator Superfamily
PF555_09835	COG1346	cytolysis
PF555_09845	COG0583	DNA-binding transcription factor activity
PF555_09850	COG0625	glutathione transferase activity
PF555_09855	COG0625	glutathione transferase activity
PF555_09860	COG0583	DNA-binding transcription factor activity
PF555_09875	COG1045	serine acetyltransferase
PF555_09880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PF555_09885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PF555_09890	COG1280	lysine exporter protein (LysE YggA)
PF555_09905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF555_09910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF555_09915	COG1126	abc transporter atp-binding protein
PF555_09920	COG0765	amino acid transport
PF555_09925	COG0765	amino acid transport
PF555_09945	COG0784	Response regulator, receiver
PF555_09945	COG2205	protein histidine kinase activity
PF555_09965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PF555_09985	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_10035	COG0583	DNA-binding transcription factor activity
PF555_10055	COG0318	PFAM AMP-dependent synthetase and ligase
PF555_10060	COG1309	transcriptional regulator
PF555_10065	COG1960	acyl-CoA dehydrogenase activity
PF555_10070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PF555_10075	COG1024	Enoyl-CoA hydratase
PF555_10080	COG4770	biotin carboxylase activity
PF555_10090	COG0583	DNA-binding transcription factor activity
PF555_10105	COG1960	acyl-CoA dehydrogenase activity
PF555_10115	COG2814	Major facilitator Superfamily
PF555_10125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PF555_10130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PF555_10135	COG2814	Major facilitator Superfamily
PF555_10140	COG1960	acyl-CoA dehydrogenase activity
PF555_10145	COG1024	Enoyl-CoA hydratase
PF555_10150	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_10155	COG1250	3-hydroxyacyl-CoA dehydrogenase
PF555_10160	COG0183	Belongs to the thiolase family
PF555_10170	COG2814	Major facilitator Superfamily
PF555_10180	COG1024	Enoyl-CoA hydratase
PF555_10190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PF555_10195	COG1960	acyl-CoA dehydrogenase activity
PF555_10200	COG2814	Major facilitator Superfamily
PF555_10205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PF555_10210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PF555_10225	COG3842	ATPase activity
PF555_10230	COG1840	ABC-type Fe3 transport system, periplasmic component
PF555_10240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PF555_10245	COG1414	Transcriptional regulator
PF555_10255	COG0583	DNA-binding transcription factor activity
PF555_10260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PF555_10265	COG1012	belongs to the aldehyde dehydrogenase family
PF555_10275	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PF555_10285	COG1012	belongs to the aldehyde dehydrogenase family
PF555_10290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF555_10295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PF555_10300	COG2267	carboxylic ester hydrolase activity
PF555_10320	COG3038	cytochrome b561
PF555_10325	COG0753	catalase activity
PF555_10355	COG2050	protein possibly involved in aromatic compounds catabolism
PF555_10365	COG3327	negative regulation of DNA-templated transcription, initiation
PF555_10370	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PF555_10375	COG0183	Belongs to the thiolase family
PF555_10380	COG1250	3-hydroxyacyl-CoA dehydrogenase
PF555_10385	COG1024	Enoyl-CoA hydratase
PF555_10390	COG1024	Enoyl-CoA hydratase
PF555_10395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PF555_10400	COG2151	metal-sulfur cluster biosynthetic enzyme
PF555_10405	COG3396	Phenylacetate-CoA oxygenase
PF555_10410	COG3460	Phenylacetate-CoA oxygenase
PF555_10415	COG3396	Phenylacetate-CoA oxygenase
PF555_10420	COG2030	dehydratase
PF555_10420	COG1012	belongs to the aldehyde dehydrogenase family
PF555_10425	COG1760	l-serine dehydratase
PF555_10430	COG0531	amino acid
PF555_10435	COG1012	belongs to the aldehyde dehydrogenase family
PF555_10460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PF555_10480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PF555_10490	COG0789	Transcriptional regulator
PF555_10500	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PF555_10515	COG2807	transmembrane transport
PF555_10520	COG0590	tRNA wobble adenosine to inosine editing
PF555_10635	COG1116	anion transmembrane transporter activity
PF555_10640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF555_10650	COG0864	Transcriptional regulator
PF555_10665	COG1733	regulation of RNA biosynthetic process
PF555_10670	COG2249	NAD(P)H dehydrogenase (quinone) activity
PF555_10675	COG0439	Biotin carboxylase
PF555_10695	COG1063	alcohol dehydrogenase
PF555_10720	COG3210	domain, Protein
PF555_10725	COG2831	hemolysin activation secretion protein
PF555_10730	COG0038	chloride channel
PF555_10735	COG4770	biotin carboxylase activity
PF555_10755	COG1914	H( )-stimulated, divalent metal cation uptake system
PF555_10760	COG0583	DNA-binding transcription factor activity
PF555_10800	COG1250	3-hydroxyacyl-CoA dehydrogenase
PF555_10820	COG2814	Major facilitator Superfamily
PF555_10835	COG1560	Kdo2-lipid A biosynthetic process
PF555_10850	COG1522	sequence-specific DNA binding
PF555_10865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PF555_10875	COG4122	O-methyltransferase activity
PF555_10905	COG4372	Transposase
PF555_10915	COG2963	transposase activity
PF555_10925	COG1538	Outer membrane efflux protein
PF555_10930	COG1137	ATPase activity
PF555_10935	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PF555_10945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PF555_10985	COG2814	Major facilitator Superfamily
PF555_11030	COG1278	Cold shock
PF555_11035	COG1280	lysine exporter protein (LysE YggA)
PF555_11065	COG1570	exodeoxyribonuclease VII activity
PF555_11115	COG0583	DNA-binding transcription factor activity
PF555_11125	COG4638	Rieske (2fe-2S)
PF555_11130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PF555_11135	COG0543	2 iron, 2 sulfur cluster binding
PF555_11135	COG0633	Ferredoxin
PF555_11140	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_11145	COG3135	benzoate transporter
PF555_11150	COG2814	Major facilitator Superfamily
PF555_11165	COG1643	Atp-dependent helicase
PF555_11170	COG0450	alkyl hydroperoxide reductase
PF555_11180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PF555_11190	COG3634	alkyl hydroperoxide reductase activity
PF555_11210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PF555_11215	COG0625	glutathione transferase activity
PF555_11225	COG2885	chlorophyll binding
PF555_11260	COG0542	response to heat
PF555_11275	COG1765	OsmC-like protein
PF555_11290	COG0667	Aldo Keto reductase
PF555_11305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PF555_11320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PF555_11330	COG0527	aspartate kinase activity
PF555_11340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PF555_11350	COG3038	cytochrome b561
PF555_11355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PF555_11360	COG2252	PERMEase
PF555_11370	COG2072	flavoprotein involved in K transport
PF555_11385	COG1741	Belongs to the pirin family
PF555_11390	COG1309	transcriptional regulator
PF555_11400	COG0300	oxidoreductase activity
PF555_11405	COG2072	flavoprotein involved in K transport
PF555_11410	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PF555_11455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PF555_11470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PF555_11485	COG2814	Major facilitator Superfamily
PF555_11490	COG1024	Enoyl-CoA hydratase
PF555_11495	COG1012	belongs to the aldehyde dehydrogenase family
PF555_11505	COG1960	acyl-CoA dehydrogenase activity
PF555_11530	COG2186	Transcriptional regulator
PF555_11535	COG1012	belongs to the aldehyde dehydrogenase family
PF555_11545	COG4948	Mandelate Racemase Muconate Lactonizing
PF555_11550	COG2271	Major facilitator Superfamily
PF555_11555	COG2721	sulfolactate sulfo-lyase activity
PF555_11560	COG0697	spore germination
PF555_11575	COG1113	amino acid transport
PF555_11595	COG1012	belongs to the aldehyde dehydrogenase family
PF555_11615	COG0531	amino acid
PF555_11625	COG1113	amino acid transport
PF555_11670	COG4269	membrane
PF555_11685	COG1902	pentaerythritol trinitrate reductase activity
PF555_11685	COG0446	pyridine nucleotide-disulphide oxidoreductase
PF555_11715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PF555_11735	COG4172	Belongs to the ABC transporter superfamily
PF555_11740	COG4239	(ABC) transporter, permease
PF555_11745	COG4174	ABC transporter (Permease)
PF555_11755	COG0741	lytic transglycosylase activity
PF555_11755	COG1388	LysM domain
PF555_11755	COG0741	lytic transglycosylase activity
PF555_11755	COG1388	LysM domain
PF555_11760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PF555_11800	COG0583	DNA-binding transcription factor activity
PF555_11805	COG1279	arginine transmembrane transporter activity
PF555_11825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PF555_11830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PF555_11835	COG0006	proline dipeptidase activity
PF555_11870	COG2194	sulfuric ester hydrolase activity
PF555_11925	COG1196	nuclear chromosome segregation
PF555_11925	COG0739	heme binding
PF555_11925	COG0741	lytic transglycosylase activity
PF555_12100	COG3617	BRO family, N-terminal domain
PF555_12255	COG0512	Glutamine amidotransferase of anthranilate synthase
PF555_12260	COG0308	aminopeptidase N
PF555_12290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PF555_12300	COG0302	gtp cyclohydrolase
PF555_12320	COG4372	Transposase
PF555_12330	COG2963	transposase activity
PF555_12345	COG3739	integral membrane protein
PF555_12365	COG2977	Belongs to the P-Pant transferase superfamily
PF555_12370	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
PF555_12375	COG1132	(ABC) transporter
PF555_12380	COG1132	(ABC) transporter
PF555_12390	COG1535	isochorismatase
PF555_12390	COG3433	isochorismatase activity
PF555_12395	COG1021	2,3-dihydroxybenzoate-AMP ligase
PF555_12400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF555_12410	COG4774	siderophore transport
PF555_12415	COG4607	ABC-type enterochelin transport system periplasmic component
PF555_12420	COG4604	ABC transporter, ATP-binding protein
PF555_12425	COG4605	iron ion homeostasis
PF555_12430	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF555_12435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF555_12450	COG2964	Protein conserved in bacteria
PF555_12460	COG1741	Belongs to the pirin family
PF555_12480	COG1309	transcriptional regulator
PF555_12490	COG4372	Transposase
PF555_12500	COG2963	transposase activity
PF555_12510	COG4948	Mandelate Racemase Muconate Lactonizing
PF555_12515	COG2814	Major facilitator Superfamily
PF555_12550	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PF555_12550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PF555_12555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PF555_12565	COG1012	belongs to the aldehyde dehydrogenase family
PF555_12580	COG0477	Major facilitator Superfamily
PF555_12585	COG0006	proline dipeptidase activity
PF555_12590	COG1902	pentaerythritol trinitrate reductase activity
PF555_12595	COG0583	DNA-binding transcription factor activity
PF555_12605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PF555_12615	COG0596	Alpha beta hydrolase
PF555_12630	COG0583	DNA-binding transcription factor activity
PF555_12635	COG1335	isochorismatase
PF555_12685	COG2879	small protein
PF555_12690	COG1966	Carbon starvation protein
PF555_12710	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PF555_12735	COG1067	ATP-dependent peptidase activity
PF555_12740	COG0583	DNA-binding transcription factor activity
PF555_12765	COG1686	Belongs to the peptidase S11 family
PF555_12770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PF555_12805	COG0616	signal peptide processing
PF555_12810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PF555_12820	COG0573	inorganic phosphate transmembrane transporter activity
PF555_12825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PF555_12830	COG1113	amino acid transport
PF555_12835	COG3961	Belongs to the TPP enzyme family
PF555_12840	COG1522	sequence-specific DNA binding
PF555_12850	COG0076	glutamate decarboxylase activity
PF555_12855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PF555_12870	COG2249	NAD(P)H dehydrogenase (quinone) activity
PF555_12880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PF555_12915	COG0352	thiamine-phosphate diphosphorylase activity
PF555_12925	COG2963	transposase activity
PF555_12935	COG4372	Transposase
PF555_12960	COG0612	Peptidase, M16
PF555_12970	COG1823	symporter activity
PF555_12975	COG0583	DNA-binding transcription factor activity
PF555_12980	COG0477	Major facilitator Superfamily
PF555_13005	COG1187	pseudouridine synthase activity
PF555_13030	COG0415	Belongs to the DNA photolyase family
PF555_13045	COG1215	transferase activity, transferring glycosyl groups
PF555_13075	COG2070	2-Nitropropane dioxygenase
PF555_13130	COG0556	nucleotide-excision repair
PF555_13150	COG0436	Aminotransferase
PF555_13160	COG0443	Heat shock 70 kDa protein
PF555_13190	COG4221	oxidoreductase activity
PF555_13200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PF555_13205	COG1381	Involved in DNA repair and RecF pathway recombination
PF555_13215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PF555_13230	COG0681	Belongs to the peptidase S26 family
PF555_13245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PF555_13265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PF555_13270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PF555_13275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PF555_13285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PF555_13290	COG4208	sulfate ABC transporter
PF555_13295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PF555_13300	COG0583	DNA-binding transcription factor activity
PF555_13305	COG4625	pathogenesis
PF555_13320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PF555_13335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PF555_13345	COG1051	belongs to the nudix hydrolase family
PF555_13345	COG1056	cytidyltransferase-related domain
PF555_13350	COG1024	Enoyl-CoA hydratase
PF555_13365	COG2814	Major facilitator Superfamily
PF555_13370	COG0047	phosphoribosylformylglycinamidine synthase activity
PF555_13370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PF555_13390	COG1473	amidohydrolase
PF555_13395	COG0824	Thioesterase
PF555_13415	COG0823	Involved in the tonB-independent uptake of proteins
PF555_13435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PF555_13455	COG2963	transposase activity
PF555_13465	COG4372	Transposase
PF555_13475	COG2963	transposase activity
PF555_13485	COG4372	Transposase
PF555_13795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PF555_13820	COG3384	dioxygenase
PF555_13830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PF555_13835	COG2878	Part of a membrane complex involved in electron transport
PF555_13840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PF555_13865	COG0768	penicillin binding
PF555_13870	COG0742	ribosomal rna small subunit methyltransferase
PF555_13885	COG0830	nickel cation binding
PF555_13895	COG0804	urea catabolic process
PF555_13935	COG1253	flavin adenine dinucleotide binding
PF555_13940	COG2851	Citrate transporter
PF555_13990	COG1773	rubredoxin
PF555_13995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PF555_14005	COG0583	DNA-binding transcription factor activity
PF555_14035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PF555_14040	COG4181	ATPase activity
PF555_14090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PF555_14110	COG0306	phosphate transporter
PF555_14120	COG3958	Transketolase
PF555_14125	COG3959	Transketolase, thiamine diphosphate binding domain
PF555_14130	COG2271	Major facilitator Superfamily
PF555_14135	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_14140	COG0583	DNA-binding transcription factor activity
PF555_14155	COG2223	nitrite transmembrane transporter activity
PF555_14160	COG2207	Transcriptional regulator
PF555_14165	COG2066	Belongs to the glutaminase family
PF555_14170	COG0242	peptide deformylase activity
PF555_14175	COG0477	Major facilitator Superfamily
PF555_14185	COG0028	Belongs to the TPP enzyme family
PF555_14200	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_14205	COG2267	carboxylic ester hydrolase activity
PF555_14215	COG2271	Major facilitator Superfamily
PF555_14230	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_14250	COG1414	Transcriptional regulator
PF555_14265	COG1024	Enoyl-CoA hydratase
PF555_14275	COG1215	transferase activity, transferring glycosyl groups
PF555_14280	COG1649	PFAM Uncharacterised BCR, COG1649
PF555_14280	COG0726	polysaccharide deacetylase
PF555_14290	COG4681	YaeQ
PF555_14300	COG0523	cobalamin synthesis protein
PF555_14310	COG1607	acyl-coa hydrolase
PF555_14320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PF555_14325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PF555_14330	COG1309	transcriptional regulator
PF555_14345	COG4372	Transposase
PF555_14355	COG2963	transposase activity
PF555_14370	COG2040	homocysteine
PF555_14375	COG0531	amino acid
PF555_14425	COG0477	Major facilitator Superfamily
PF555_14460	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PF555_14475	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PF555_14480	COG2963	transposase activity
PF555_14490	COG4372	Transposase
PF555_14525	COG0629	single-stranded DNA binding
PF555_14570	COG0582	viral genome integration into host DNA
PF555_14580	COG0405	Gamma-glutamyltransferase
PF555_14585	COG2814	Major facilitator Superfamily
PF555_14595	COG2050	protein possibly involved in aromatic compounds catabolism
PF555_14610	COG1090	epimerase
PF555_14630	COG0420	3'-5' exonuclease activity
PF555_14655	COG0735	belongs to the Fur family
PF555_14660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PF555_14680	COG0121	glutamine amidotransferase
PF555_14695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PF555_14705	COG0210	DNA helicase
PF555_14710	COG2885	chlorophyll binding
PF555_14715	COG0204	Acyl-transferase
PF555_14730	COG2894	cell division
PF555_14745	COG1280	lysine exporter protein (LysE YggA)
PF555_14750	COG1674	ftsk spoiiie
PF555_14750	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PF555_14755	COG0492	ferredoxin-NADP+ reductase activity
PF555_14760	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PF555_14770	COG0456	acetyltransferase
PF555_14815	COG1981	membrane
PF555_14830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PF555_14830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PF555_14850	COG1012	belongs to the aldehyde dehydrogenase family
PF555_14860	COG0657	acetylesterase activity
PF555_14870	COG0473	3-isopropylmalate dehydrogenase activity
PF555_14875	COG0583	DNA-binding transcription factor activity
PF555_14895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PF555_14920	COG0564	pseudouridine synthase activity
PF555_14930	COG0358	DNA primase activity
PF555_14945	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PF555_14975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PF555_15005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PF555_15015	COG0352	thiamine-phosphate diphosphorylase activity
PF555_15015	COG0351	phosphomethylpyrimidine kinase
PF555_15015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PF555_15020	COG1652	LysM domain
PF555_15045	COG1399	metal-binding, possibly nucleic acid-binding protein
PF555_15050	COG3101	peptidyl-lysine hydroxylation
PF555_15055	COG0009	L-threonylcarbamoyladenylate synthase
PF555_15060	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PF555_15065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PF555_15080	COG4106	trans-aconitate 2-methyltransferase activity
PF555_15095	COG0596	Alpha beta hydrolase
PF555_15095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PF555_15095	COG2226	methyltransferase
PF555_15100	COG1877	trehalose-phosphatase activity
PF555_15105	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PF555_15110	COG2223	nitrite transmembrane transporter activity
PF555_15130	COG1196	nuclear chromosome segregation
PF555_15140	COG0730	response to heat
PF555_15155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PF555_15165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PF555_15215	COG0489	protein tyrosine kinase activity
PF555_15225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PF555_15225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PF555_15255	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PF555_15260	COG2081	HI0933 family
PF555_15270	COG0668	transmembrane transport
PF555_15290	COG0583	DNA-binding transcription factor activity
PF555_15315	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PF555_15320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PF555_15350	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PF555_15375	COG3706	GGDEF domain
PF555_15390	COG0745	RESPONSE REGULATOR receiver
PF555_15410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PF555_15460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PF555_15475	COG0583	DNA-binding transcription factor activity
PF555_15485	COG0583	DNA-binding transcription factor activity
PF555_15500	COG0583	DNA-binding transcription factor activity
PF555_15505	COG1053	succinate dehydrogenase
PF555_15520	COG1309	transcriptional regulator
PF555_15525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PF555_15530	COG2814	Major facilitator Superfamily
PF555_15535	COG1960	acyl-CoA dehydrogenase activity
PF555_15540	COG0583	DNA-binding transcription factor activity
PF555_15545	COG1063	alcohol dehydrogenase
PF555_15575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PF555_15580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PF555_15585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PF555_15605	COG2132	Multicopper oxidase
PF555_15615	COG0561	phosphatase activity
PF555_15620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PF555_15645	COG1214	PFAM Peptidase M22, glycoprotease
PF555_15675	COG4372	Transposase
PF555_15685	COG2963	transposase activity
PF555_15715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PF555_15725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PF555_15730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PF555_15735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PF555_15795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PF555_15805	COG1846	Transcriptional regulator
PF555_15810	COG1764	response to oxidative stress
PF555_15850	COG0037	tRNA processing
PF555_15860	COG0248	Ppx GppA phosphatase
PF555_15890	COG0072	phenylalanine-tRNA ligase activity
PF555_15935	COG1238	metal cluster binding
PF555_15940	COG0625	glutathione transferase activity
PF555_15955	COG0318	PFAM AMP-dependent synthetase and ligase
PF555_15960	COG3028	Belongs to the UPF0307 family
PF555_15965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF555_15985	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PF555_15990	COG0617	tRNA 3'-terminal CCA addition
PF555_15995	COG1555	photosystem II stabilization
PF555_16000	COG3956	TIGRFAM MazG family protein
PF555_16010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PF555_16030	COG0784	Response regulator, receiver
PF555_16030	COG2205	protein histidine kinase activity
PF555_16030	COG5002	protein histidine kinase activity
PF555_16035	COG1024	Enoyl-CoA hydratase
PF555_16040	COG2084	Dehydrogenase
PF555_16045	COG3622	Belongs to the hyi family
PF555_16075	COG0697	spore germination
PF555_16085	COG2814	Major facilitator Superfamily
PF555_16090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PF555_16100	COG0583	DNA-binding transcription factor activity
PF555_16110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PF555_16120	COG0084	hydrolase, TatD family'
PF555_16135	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PF555_16165	COG0440	acetolactate synthase activity
PF555_16170	COG0028	Belongs to the TPP enzyme family
PF555_16195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PF555_16200	COG1136	(ABC) transporter
PF555_16200	COG0577	efflux transmembrane transporter activity
PF555_16205	COG1538	Outer membrane efflux protein
PF555_16220	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PF555_16225	COG1162	GTPase activity
PF555_16235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PF555_16275	COG1426	Protein conserved in bacteria
PF555_16310	COG0793	Belongs to the peptidase S41A family
PF555_16325	COG2267	carboxylic ester hydrolase activity
PF555_16335	COG1012	belongs to the aldehyde dehydrogenase family
PF555_16340	COG3265	gluconokinase activity
PF555_16350	COG0800	Aldolase
PF555_16360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PF555_16365	COG0280	phosphate acetyltransferase
PF555_16365	COG0857	belongs to the CobB CobQ family
PF555_16370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
PF555_16370	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PF555_16390	COG0740	serine-type endopeptidase activity
PF555_16400	COG4774	siderophore transport
PF555_16410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PF555_16420	COG2813	Specifically methylates the guanine in position
PF555_16420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PF555_16520	COG0788	formyltetrahydrofolate deformylase activity
PF555_16545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PF555_16545	COG4651	solute:proton antiporter activity
PF555_16565	COG0724	RNA recognition motif
PF555_16570	COG0210	DNA helicase
PF555_16595	COG1733	regulation of RNA biosynthetic process
PF555_16605	COG2900	Belongs to the SlyX family
PF555_16610	COG0488	(ABC) transporter
PF555_16615	COG1280	lysine exporter protein (LysE YggA)
PF555_16620	COG1560	Kdo2-lipid A biosynthetic process
PF555_16630	COG1301	dicarboxylic acid transport
PF555_16685	COG0473	3-isopropylmalate dehydrogenase activity
PF555_16750	COG0583	DNA-binding transcription factor activity
PF555_16760	COG0625	glutathione transferase activity
PF555_16765	COG2378	regulation of single-species biofilm formation
PF555_16770	COG0546	phosphoglycolate phosphatase activity
PF555_16780	COG1530	ribonuclease E activity
PF555_16785	COG0318	PFAM AMP-dependent synthetase and ligase
PF555_16800	COG0583	DNA-binding transcription factor activity
PF555_16805	COG1028	Short-chain dehydrogenase reductase Sdr
PF555_16810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PF555_16820	COG0534	Mate efflux family protein
PF555_16835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PF555_16845	COG2963	transposase activity
PF555_16855	COG4372	Transposase
PF555_16865	COG4372	Transposase
PF555_16875	COG2963	transposase activity
PF555_16900	COG0493	'glutamate synthase
PF555_16900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PF555_16910	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PF555_16915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF555_16930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PF555_16940	COG0644	oxidoreductase
PF555_16940	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
PF555_16950	COG0425	Belongs to the sulfur carrier protein TusA family
PF555_16955	COG4535	Mg2 and Co2 transporter CorC
PF555_16965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PF555_16985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PF555_16990	COG0475	glutathione-regulated potassium exporter activity
PF555_16990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PF555_17005	COG0484	heat shock protein binding
PF555_17010	COG0789	Transcriptional regulator
PF555_17015	COG0598	Magnesium transport protein CorA
PF555_17030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PF555_17035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PF555_17040	COG1074	ATP-dependent DNA helicase activity
PF555_17045	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PF555_17065	COG2226	methyltransferase
PF555_17080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PF555_17085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PF555_17100	COG2111	Na H antiporter
PF555_17100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PF555_17105	COG1006	Multisubunit Na H antiporter MnhC subunit
PF555_17110	COG0651	ATP synthesis coupled electron transport
PF555_17115	COG1863	multisubunit Na H antiporter MnhE subunit
PF555_17120	COG2212	antiporter activity
PF555_17125	COG1320	monovalent cation:proton antiporter activity
PF555_17140	COG0195	Participates in both transcription termination and antitermination
PF555_17190	COG0237	dephospho-CoA kinase activity
PF555_17200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PF555_17215	COG0497	DNA recombination
PF555_17225	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PF555_17255	COG2169	Transcriptional regulator
PF555_17255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PF555_17260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PF555_17310	COG0789	Transcriptional regulator
PF555_17320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PF555_17335	COG0326	Molecular chaperone. Has ATPase activity
PF555_17350	COG2056	Na+-H+ antiporter family
PF555_17450	COG0546	phosphoglycolate phosphatase activity
PF555_17455	COG1716	ATPase activity
PF555_17500	COG0181	hydroxymethylbilane synthase activity
PF555_17510	COG3275	phosphorelay sensor kinase activity
PF555_17530	COG1538	Outer membrane efflux protein
PF555_17535	COG0697	spore germination
PF555_17560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PF555_17565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PF555_17570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PF555_17575	COG0772	Belongs to the SEDS family
PF555_17600	COG4974	Belongs to the 'phage' integrase family
PF555_17605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PF555_17615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PF555_17625	COG2197	response regulator
PF555_17640	COG0793	Belongs to the peptidase S41A family
PF555_17645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PF555_17650	COG0795	lipopolysaccharide-transporting ATPase activity
PF555_17690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PF555_17690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PF555_17700	COG0004	ammonium transporteR
PF555_17705	COG0347	Belongs to the P(II) protein family
PF555_17795	COG2132	Multicopper oxidase
PF555_17810	COG2205	protein histidine kinase activity
PF555_17815	COG2217	Heavy metal translocating P-type atpase
PF555_17850	COG4774	siderophore transport
PF555_17855	COG4607	ABC-type enterochelin transport system periplasmic component
PF555_17860	COG4604	ABC transporter, ATP-binding protein
PF555_17865	COG4605	iron ion homeostasis
PF555_17870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF555_17875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF555_17890	COG2964	Protein conserved in bacteria
PF555_17900	COG1741	Belongs to the pirin family
PF555_17920	COG1309	transcriptional regulator
PF555_17930	COG4372	Transposase
PF555_17940	COG2963	transposase activity
PF555_17970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF555_17975	COG0235	Class ii aldolase
PF555_17980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PF555_18000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PF555_18015	COG0318	PFAM AMP-dependent synthetase and ligase
PF555_18025	COG0477	Major facilitator Superfamily
PF555_18030	COG2860	membrane
PF555_18035	COG3012	SEC-C Motif Domain Protein
PF555_18040	COG1253	flavin adenine dinucleotide binding
PF555_18050	COG0477	Major facilitator Superfamily
PF555_18060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PF555_18100	COG0655	NAD(P)H dehydrogenase (quinone) activity
PF555_18110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PF555_18180	COG0758	DNA mediated transformation
PF555_18190	COG0697	spore germination
PF555_18195	COG1309	transcriptional regulator
PF555_18210	COG0386	Belongs to the glutathione peroxidase family
PF555_18280	COG1121	(ABC) transporter
PF555_18285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PF555_18290	COG1280	lysine exporter protein (LysE YggA)
PF555_18295	COG2837	iron assimilation
PF555_18305	COG0281	malic enzyme
PF555_18350	COG0519	Catalyzes the synthesis of GMP from XMP
PF555_18350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PF555_18355	COG4399	Belongs to the UPF0754 family
PF555_18360	COG2259	Doxx family
PF555_18365	COG0586	Pfam SNARE associated Golgi protein
PF555_18390	COG1126	abc transporter atp-binding protein
PF555_18410	COG2188	Transcriptional regulator
PF555_18420	COG0523	cobalamin synthesis protein
PF555_18430	COG1113	amino acid transport
PF555_18440	COG0625	glutathione transferase activity
PF555_18460	COG1683	Conserved Protein
PF555_18470	COG0385	Bile acid
PF555_18475	COG1335	isochorismatase
PF555_18480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PF555_18500	COG2116	formate transmembrane transporter activity
PF555_18505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PF555_18510	COG2133	pyrroloquinoline quinone binding
PF555_18515	COG2983	Belongs to the UPF0260 family
PF555_18535	COG1194	a g-specific adenine glycosylase
PF555_18550	COG2818	Glycosylase
PF555_18555	COG1064	alcohol dehydrogenase
PF555_18560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF555_18575	COG0583	DNA-binding transcription factor activity
PF555_18580	COG0656	L-ascorbic acid biosynthetic process
PF555_18585	COG2814	Major facilitator Superfamily
PF555_18630	COG2951	lytic endotransglycosylase activity
PF555_18635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PF555_18650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PF555_18660	COG0671	phosphoesterase, PA-phosphatase related
PF555_18665	COG0861	Integral membrane protein TerC family
PF555_18675	COG0754	glutathionylspermidine amidase activity
PF555_18685	COG0402	S-adenosylhomocysteine deaminase activity
PF555_18700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PF555_18705	COG1230	cation diffusion facilitator family transporter
PF555_18720	COG0706	membrane insertase activity
PF555_18795	COG0358	DNA primase activity
PF555_18835	COG0194	GDP metabolic process
PF555_18860	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PF555_18915	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PF555_18960	COG0419	ATPase involved in DNA repair
PF555_18985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PF555_18985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PF555_18990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PF555_19015	COG0756	dUTP diphosphatase activity
PF555_19230	COG1475	DNA binding
PF555_19235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PF555_19340	COG0791	NLP P60 protein