locus-tag	class	description
M1S31_00010	COG0592	DNA-directed DNA polymerase activity
M1S31_00020	COG0187	DNA topoisomerase II activity
M1S31_00030	COG0586	Pfam SNARE associated Golgi protein
M1S31_00035	COG0488	(ABC) transporter
M1S31_00060	COG0596	Alpha beta hydrolase
M1S31_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
M1S31_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M1S31_00110	COG0733	neurotransmitter:sodium symporter activity
M1S31_00150	COG2233	PERMEase
M1S31_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S31_00200	COG2814	Major facilitator Superfamily
M1S31_00205	COG0656	L-ascorbic acid biosynthetic process
M1S31_00210	COG0583	DNA-binding transcription factor activity
M1S31_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S31_00230	COG1064	alcohol dehydrogenase
M1S31_00235	COG2818	Glycosylase
M1S31_00250	COG1194	a g-specific adenine glycosylase
M1S31_00270	COG2983	Belongs to the UPF0260 family
M1S31_00275	COG2133	pyrroloquinoline quinone binding
M1S31_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1S31_00285	COG2116	formate transmembrane transporter activity
M1S31_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S31_00310	COG1335	isochorismatase
M1S31_00315	COG0385	Bile acid
M1S31_00320	COG0534	Mate efflux family protein
M1S31_00325	COG1683	Conserved Protein
M1S31_00345	COG0625	glutathione transferase activity
M1S31_00355	COG1113	amino acid transport
M1S31_00365	COG0523	cobalamin synthesis protein
M1S31_00375	COG2188	Transcriptional regulator
M1S31_00405	COG0010	Belongs to the arginase family
M1S31_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1S31_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M1S31_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1S31_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M1S31_00540	COG0534	Mate efflux family protein
M1S31_00545	COG0436	Aminotransferase
M1S31_00550	COG2733	membrane
M1S31_00565	COG2918	glutathione biosynthetic process
M1S31_00580	COG0791	NLP P60 protein
M1S31_00580	COG1388	LysM domain
M1S31_00595	COG3150	esterase
M1S31_00605	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
M1S31_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S31_00630	COG2233	PERMEase
M1S31_00635	COG2351	hydroxyisourate hydrolase activity
M1S31_00670	COG3706	GGDEF domain
M1S31_00685	COG1393	Belongs to the ArsC family
M1S31_00690	COG0708	Exodeoxyribonuclease III
M1S31_00710	COG0189	ligase activity
M1S31_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1S31_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1S31_00755	COG4942	peptidase
M1S31_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1S31_00775	COG2119	membrane
M1S31_00780	COG4774	siderophore transport
M1S31_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S31_00785	COG0426	domain, Protein
M1S31_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1S31_00830	COG1902	pentaerythritol trinitrate reductase activity
M1S31_00835	COG1519	Transferase
M1S31_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1S31_00845	COG0668	transmembrane transport
M1S31_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S31_00860	COG1335	isochorismatase
M1S31_00865	COG1522	sequence-specific DNA binding
M1S31_00870	COG3328	transposase activity
M1S31_00900	COG2205	protein histidine kinase activity
M1S31_00900	COG2198	Histidine kinase
M1S31_00900	COG0784	Response regulator, receiver
M1S31_00905	COG3162	membrane
M1S31_00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1S31_00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S31_00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1S31_00945	COG1309	transcriptional regulator
M1S31_00965	COG0351	phosphomethylpyrimidine kinase
M1S31_00965	COG0352	thiamine-phosphate diphosphorylase activity
M1S31_00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1S31_00975	COG2814	Major facilitator Superfamily
M1S31_00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1S31_01000	COG1113	amino acid transport
M1S31_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1S31_01015	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_01025	COG1335	isochorismatase
M1S31_01055	COG2814	Major facilitator Superfamily
M1S31_01060	COG0583	DNA-binding transcription factor activity
M1S31_01080	COG0667	Aldo Keto reductase
M1S31_01115	COG1733	regulation of RNA biosynthetic process
M1S31_01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S31_01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1S31_01200	COG2329	Antibiotic biosynthesis monooxygenase
M1S31_01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M1S31_01260	COG0427	acetyl-CoA hydrolase
M1S31_01285	COG0659	secondary active sulfate transmembrane transporter activity
M1S31_01290	COG4221	oxidoreductase activity
M1S31_01295	COG2873	o-acetylhomoserine
M1S31_01300	COG0488	(ABC) transporter
M1S31_01385	COG0833	amino acid
M1S31_01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1S31_01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1S31_01500	COG0067	glutamate synthase
M1S31_01500	COG0069	glutamate synthase activity
M1S31_01500	COG0070	glutamate synthase
M1S31_01505	COG0493	'glutamate synthase
M1S31_01515	COG1704	LemA family
M1S31_01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M1S31_01540	COG3307	-O-antigen
M1S31_01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1S31_01580	COG0194	GDP metabolic process
M1S31_01630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M1S31_01650	COG5380	lipid catabolic process
M1S31_01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M1S31_01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1S31_01685	COG0277	FAD linked oxidase domain protein
M1S31_01695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M1S31_01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S31_01715	COG1289	transmembrane transporter activity
M1S31_01725	COG0628	permease
M1S31_01730	COG1192	Involved in chromosome partitioning
M1S31_01760	COG0833	amino acid
M1S31_01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1S31_01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1S31_01780	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_01820	COG0583	DNA-binding transcription factor activity
M1S31_01865	COG0517	IMP dehydrogenase activity
M1S31_01870	COG1983	PspC domain protein
M1S31_01880	COG1960	acyl-CoA dehydrogenase activity
M1S31_01895	COG0408	coproporphyrinogen oxidase activity
M1S31_01915	COG0513	Belongs to the DEAD box helicase family
M1S31_01925	COG1127	ABC transporter
M1S31_01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M1S31_01940	COG2854	intermembrane phospholipid transfer
M1S31_01950	COG0598	Magnesium transport protein CorA
M1S31_01960	COG0494	nUDIX hydrolase
M1S31_01965	COG1040	competence protein
M1S31_01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1S31_01990	COG1946	Acyl-CoA thioesterase
M1S31_01995	COG1301	dicarboxylic acid transport
M1S31_02010	COG1959	2 iron, 2 sulfur cluster binding
M1S31_02015	COG1017	nitric oxide dioxygenase activity
M1S31_02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S31_02020	COG0433	COG0433 Predicted ATPase
M1S31_02025	COG0626	cystathionine gamma-synthase activity
M1S31_02180	COG1960	acyl-CoA dehydrogenase activity
M1S31_02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M1S31_02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M1S31_02220	COG0339	signal peptide processing
M1S31_02225	COG0557	exoribonuclease II activity
M1S31_02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1S31_02275	COG2169	Transcriptional regulator
M1S31_02280	COG0697	spore germination
M1S31_02285	COG1295	ribonuclease BN
M1S31_02320	COG1702	phosphate starvation-inducible protein PhoH
M1S31_02330	COG0739	heme binding
M1S31_02330	COG0741	lytic transglycosylase activity
M1S31_02330	COG1196	nuclear chromosome segregation
M1S31_02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M1S31_02365	COG1183	phosphatidylcholine synthase activity
M1S31_02410	COG1960	acyl-CoA dehydrogenase activity
M1S31_02415	COG1309	transcriptional regulator
M1S31_02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1S31_02435	COG1960	acyl-CoA dehydrogenase activity
M1S31_02455	COG2969	positive regulation of protein catabolic process
M1S31_02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M1S31_02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M1S31_02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M1S31_02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1S31_02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1S31_02520	COG1408	metallophosphoesterase
M1S31_02530	COG2199	diguanylate cyclase activity
M1S31_02590	COG1607	acyl-coa hydrolase
M1S31_02620	COG2350	Protein conserved in bacteria
M1S31_02630	COG0613	PHP domain protein
M1S31_02635	COG3781	membrane
M1S31_02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1S31_02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1S31_02660	COG1862	Preprotein translocase
M1S31_02690	COG2205	protein histidine kinase activity
M1S31_02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M1S31_02715	COG0726	polysaccharide deacetylase
M1S31_02720	COG0463	Glycosyl transferase, family 2
M1S31_02725	COG0438	transferase activity, transferring glycosyl groups
M1S31_02790	COG0625	glutathione transferase activity
M1S31_02795	COG0583	DNA-binding transcription factor activity
M1S31_02800	COG1960	acyl-CoA dehydrogenase activity
M1S31_02805	COG1960	acyl-CoA dehydrogenase activity
M1S31_02815	COG2205	protein histidine kinase activity
M1S31_02820	COG0745	RESPONSE REGULATOR receiver
M1S31_02825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M1S31_02845	COG2096	Adenosyltransferase
M1S31_02895	COG0285	dihydrofolate synthase activity
M1S31_02915	COG0450	alkyl hydroperoxide reductase
M1S31_02930	COG0477	Major facilitator Superfamily
M1S31_02935	COG1272	protein, Hemolysin III
M1S31_02965	COG0183	Belongs to the thiolase family
M1S31_02970	COG2207	Transcriptional regulator
M1S31_02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S31_03010	COG0183	Belongs to the thiolase family
M1S31_03020	COG2885	chlorophyll binding
M1S31_03020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M1S31_03030	COG1690	Belongs to the RtcB family
M1S31_03035	COG0833	amino acid
M1S31_03045	COG2233	PERMEase
M1S31_03050	COG1217	gtp-binding protein TYPA
M1S31_03075	COG2094	Belongs to the DNA glycosylase MPG family
M1S31_03095	COG1902	pentaerythritol trinitrate reductase activity
M1S31_03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S31_03115	COG0354	folic acid binding
M1S31_03125	COG3189	MarR family transcriptional regulator
M1S31_03130	COG2824	Alkylphosphonate utilization operon protein PhnA
M1S31_03135	COG3422	double-strand break repair
M1S31_03175	COG0840	transmembrane signaling receptor activity
M1S31_03195	COG5510	response to toxic substance
M1S31_03205	COG2832	Protein of unknown function (DUF454)
M1S31_03210	COG1376	ErfK ybiS ycfS ynhG family protein
M1S31_03250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M1S31_03260	COG1289	transmembrane transporter activity
M1S31_03265	COG2814	Major facilitator Superfamily
M1S31_03285	COG1115	amino acid carrier protein
M1S31_03290	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1S31_03300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
M1S31_03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1S31_03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1S31_03345	COG1077	Cell shape determining protein MreB Mrl
M1S31_03350	COG1792	Involved in formation and maintenance of cell shape
M1S31_03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M1S31_03360	COG0424	maF-like protein
M1S31_03365	COG1530	ribonuclease E activity
M1S31_03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S31_03385	COG0560	Phosphoserine phosphatase
M1S31_03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S31_03420	COG2207	Transcriptional regulator
M1S31_03440	COG1113	amino acid transport
M1S31_03445	COG2828	Protein conserved in bacteria
M1S31_03450	COG0142	geranyltranstransferase activity
M1S31_03455	COG2315	Protein conserved in bacteria
M1S31_03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1S31_03490	COG2194	sulfuric ester hydrolase activity
M1S31_03495	COG0745	RESPONSE REGULATOR receiver
M1S31_03500	COG0642	Histidine kinase
M1S31_03510	COG0004	ammonium transporteR
M1S31_03515	COG0583	DNA-binding transcription factor activity
M1S31_03535	COG0525	valine-tRNA ligase activity
M1S31_03545	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_03555	COG0393	Putative heavy-metal-binding
M1S31_03560	COG0393	Putative heavy-metal-binding
M1S31_03565	COG1538	Outer membrane efflux protein
M1S31_03575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S31_03580	COG0671	phosphoesterase, PA-phosphatase related
M1S31_03610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1S31_03625	COG1648	precorrin-2 dehydrogenase activity
M1S31_03625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1S31_03630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1S31_03635	COG1733	regulation of RNA biosynthetic process
M1S31_03645	COG0531	amino acid
M1S31_03660	COG0321	lipoyl(octanoyl) transferase activity
M1S31_03665	COG2921	Belongs to the UPF0250 family
M1S31_03705	COG2009	succinate dehydrogenase
M1S31_03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M1S31_03715	COG1053	succinate dehydrogenase
M1S31_03720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1S31_03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S31_03765	COG2354	Protein conserved in bacteria
M1S31_03770	COG2321	neutral zinc metallopeptidase
M1S31_03790	COG2843	Capsule synthesis protein
M1S31_03805	COG0589	response to stress
M1S31_03825	COG0505	Belongs to the CarA family
M1S31_03850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1S31_03855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1S31_03905	COG0477	Major facilitator Superfamily
M1S31_03910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M1S31_03925	COG1597	lipid kinase activity
M1S31_03930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1S31_03960	COG0584	glycerophosphoryl diester phosphodiesterase
M1S31_03980	COG0741	lytic transglycosylase activity
M1S31_04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M1S31_04015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S31_04045	COG0778	Nitroreductase
M1S31_04060	COG1929	Belongs to the glycerate kinase type-1 family
M1S31_04065	COG0243	molybdopterin cofactor binding
M1S31_04070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1S31_04075	COG3339	Conserved Protein
M1S31_04085	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
M1S31_04100	COG1113	amino acid transport
M1S31_04110	COG0019	diaminopimelate decarboxylase activity
M1S31_04120	COG1280	lysine exporter protein (LysE YggA)
M1S31_04125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1S31_04155	COG0463	Glycosyl transferase, family 2
M1S31_04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S31_04210	COG4591	ABC-type transport system involved in lipoprotein release permease component
M1S31_04215	COG1136	(ABC) transporter
M1S31_04220	COG2333	competence protein COMEC
M1S31_04220	COG0658	competence protein
M1S31_04230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M1S31_04230	COG0616	signal peptide processing
M1S31_04240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1S31_04250	COG0628	permease
M1S31_04285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1S31_04305	COG0823	Involved in the tonB-independent uptake of proteins
M1S31_04325	COG0824	Thioesterase
M1S31_04330	COG1473	amidohydrolase
M1S31_04350	COG0047	phosphoribosylformylglycinamidine synthase activity
M1S31_04350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1S31_04355	COG2814	Major facilitator Superfamily
M1S31_04365	COG1024	Enoyl-CoA hydratase
M1S31_04370	COG1051	belongs to the nudix hydrolase family
M1S31_04370	COG1056	cytidyltransferase-related domain
M1S31_04380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1S31_04395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M1S31_04410	COG4625	pathogenesis
M1S31_04415	COG0583	DNA-binding transcription factor activity
M1S31_04420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M1S31_04425	COG4208	sulfate ABC transporter
M1S31_04430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M1S31_04440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M1S31_04445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1S31_04450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1S31_04470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1S31_04485	COG0681	Belongs to the peptidase S26 family
M1S31_04500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1S31_04510	COG1381	Involved in DNA repair and RecF pathway recombination
M1S31_04515	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M1S31_04525	COG4221	oxidoreductase activity
M1S31_04555	COG0436	Aminotransferase
M1S31_04575	COG0556	nucleotide-excision repair
M1S31_04630	COG2070	2-Nitropropane dioxygenase
M1S31_04660	COG1215	transferase activity, transferring glycosyl groups
M1S31_04675	COG0415	Belongs to the DNA photolyase family
M1S31_04685	COG1252	NADH dehydrogenase
M1S31_04690	COG1686	Belongs to the peptidase S11 family
M1S31_04705	COG1187	pseudouridine synthase activity
M1S31_04730	COG0477	Major facilitator Superfamily
M1S31_04735	COG0583	DNA-binding transcription factor activity
M1S31_04740	COG1823	symporter activity
M1S31_04750	COG0612	Peptidase, M16
M1S31_04775	COG0352	thiamine-phosphate diphosphorylase activity
M1S31_04810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S31_04825	COG1309	transcriptional regulator
M1S31_04835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1S31_04840	COG0076	glutamate decarboxylase activity
M1S31_04850	COG1522	sequence-specific DNA binding
M1S31_04855	COG3961	Belongs to the TPP enzyme family
M1S31_04860	COG1113	amino acid transport
M1S31_04865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1S31_04870	COG0573	inorganic phosphate transmembrane transporter activity
M1S31_04880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M1S31_04885	COG0616	signal peptide processing
M1S31_04920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1S31_04925	COG1686	Belongs to the peptidase S11 family
M1S31_04950	COG0583	DNA-binding transcription factor activity
M1S31_04955	COG1067	ATP-dependent peptidase activity
M1S31_05000	COG1966	Carbon starvation protein
M1S31_05005	COG2879	small protein
M1S31_05040	COG2508	Transcriptional regulator
M1S31_05040	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M1S31_05060	COG1113	amino acid transport
M1S31_05065	COG0583	DNA-binding transcription factor activity
M1S31_05070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S31_05075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S31_05085	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_05095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S31_05100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S31_05100	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
M1S31_05135	COG2814	Major facilitator Superfamily
M1S31_05140	COG4948	Mandelate Racemase Muconate Lactonizing
M1S31_05150	COG1309	transcriptional regulator
M1S31_05170	COG1741	Belongs to the pirin family
M1S31_05180	COG2964	Protein conserved in bacteria
M1S31_05195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S31_05200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1S31_05205	COG4605	iron ion homeostasis
M1S31_05210	COG4604	ABC transporter, ATP-binding protein
M1S31_05215	COG4607	ABC-type enterochelin transport system periplasmic component
M1S31_05220	COG4774	siderophore transport
M1S31_05230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S31_05235	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1S31_05240	COG1535	isochorismatase
M1S31_05240	COG3433	isochorismatase activity
M1S31_05255	COG1132	(ABC) transporter
M1S31_05260	COG1132	(ABC) transporter
M1S31_05265	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M1S31_05275	COG1169	isochorismate synthase
M1S31_05290	COG3739	integral membrane protein
M1S31_05315	COG0302	gtp cyclohydrolase
M1S31_05325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M1S31_05355	COG0308	aminopeptidase N
M1S31_05360	COG0512	Glutamine amidotransferase of anthranilate synthase
M1S31_05375	COG0174	glutamine synthetase
M1S31_05385	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
M1S31_05420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1S31_05425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1S31_05430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1S31_05450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1S31_05455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1S31_05460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
M1S31_05475	COG1960	acyl-CoA dehydrogenase activity
M1S31_05480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1S31_05485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S31_05495	COG2223	nitrite transmembrane transporter activity
M1S31_05505	COG0024	Methionine aminopeptidase
M1S31_05510	COG0052	Belongs to the universal ribosomal protein uS2 family
M1S31_05525	COG2207	Transcriptional regulator
M1S31_05550	COG2951	lytic endotransglycosylase activity
M1S31_05555	COG0772	Belongs to the SEDS family
M1S31_05570	COG0842	Transport permease protein
M1S31_05575	COG1131	(ABC) transporter
M1S31_05620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S31_05635	COG4215	(ABC) transporter
M1S31_05640	COG4160	amino acid transport
M1S31_05645	COG4598	ABC transporter
M1S31_05655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1S31_05660	COG0826	peptidase U32
M1S31_05665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S31_05680	COG1720	tRNA m6t6A37 methyltransferase activity
M1S31_05690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1S31_05705	COG0642	Histidine kinase
M1S31_05715	COG0494	nUDIX hydrolase
M1S31_05725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1S31_05730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M1S31_05735	COG3139	Protein of unknown function (DUF1315)
M1S31_05740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M1S31_05745	COG1301	dicarboxylic acid transport
M1S31_05750	COG1960	acyl-CoA dehydrogenase activity
M1S31_05755	COG2819	hydrolase of the alpha beta superfamily
M1S31_05765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M1S31_05775	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1S31_05780	COG1234	tRNA 3'-trailer cleavage
M1S31_05810	COG2363	Small membrane protein
M1S31_05835	COG0513	Belongs to the DEAD box helicase family
M1S31_05845	COG0778	Nitroreductase
M1S31_06195	COG1286	toxin biosynthetic process
M1S31_06220	COG4783	chaperone-mediated protein folding
M1S31_06225	COG1610	YqeY-like protein
M1S31_06325	COG3111	PFAM Bacterial OB fold (BOF) protein
M1S31_06350	COG3243	poly(R)-hydroxyalkanoic acid synthase
M1S31_06355	COG0786	glutamate:sodium symporter activity
M1S31_06365	COG2186	Transcriptional regulator
M1S31_06415	COG0477	Major facilitator Superfamily
M1S31_06445	COG2985	domain, Protein
M1S31_06455	COG2995	paraquat-inducible protein a
M1S31_06460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M1S31_06460	COG3008	intermembrane lipid transfer
M1S31_06470	COG1794	racemase activity, acting on amino acids and derivatives
M1S31_06565	COG0488	(ABC) transporter
M1S31_06570	COG3173	Aminoglycoside phosphotransferase
M1S31_06580	COG2433	Pfam Transposase IS66
M1S31_06600	COG1309	transcriptional regulator
M1S31_06605	COG1741	Belongs to the pirin family
M1S31_06620	COG2072	flavoprotein involved in K transport
M1S31_06630	COG2252	PERMEase
M1S31_06635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
M1S31_06640	COG3038	cytochrome b561
M1S31_06650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M1S31_06660	COG0527	aspartate kinase activity
M1S31_06670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1S31_06680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M1S31_06695	COG0667	Aldo Keto reductase
M1S31_06715	COG1765	OsmC-like protein
M1S31_06730	COG0542	response to heat
M1S31_06765	COG2885	chlorophyll binding
M1S31_06775	COG0625	glutathione transferase activity
M1S31_06780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M1S31_06800	COG3634	alkyl hydroperoxide reductase activity
M1S31_06810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
M1S31_06820	COG0450	alkyl hydroperoxide reductase
M1S31_06825	COG1643	Atp-dependent helicase
M1S31_06840	COG2814	Major facilitator Superfamily
M1S31_06845	COG3135	benzoate transporter
M1S31_06850	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_06855	COG0633	Ferredoxin
M1S31_06855	COG0543	2 iron, 2 sulfur cluster binding
M1S31_06860	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1S31_06865	COG4638	Rieske (2fe-2S)
M1S31_06875	COG0583	DNA-binding transcription factor activity
M1S31_06925	COG1570	exodeoxyribonuclease VII activity
M1S31_06955	COG1280	lysine exporter protein (LysE YggA)
M1S31_06960	COG1278	Cold shock
M1S31_06995	COG2814	Major facilitator Superfamily
M1S31_07030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M1S31_07030	COG0517	IMP dehydrogenase activity
M1S31_07035	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M1S31_07045	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M1S31_07050	COG1137	ATPase activity
M1S31_07055	COG1538	Outer membrane efflux protein
M1S31_07085	COG4122	O-methyltransferase activity
M1S31_07095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
M1S31_07110	COG1522	sequence-specific DNA binding
M1S31_07115	COG5006	permease, DMT superfamily
M1S31_07125	COG1560	Kdo2-lipid A biosynthetic process
M1S31_07140	COG2814	Major facilitator Superfamily
M1S31_07160	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S31_07210	COG0583	DNA-binding transcription factor activity
M1S31_07215	COG1914	H( )-stimulated, divalent metal cation uptake system
M1S31_07235	COG4770	biotin carboxylase activity
M1S31_07240	COG0038	chloride channel
M1S31_07260	COG1309	transcriptional regulator
M1S31_07270	COG1063	alcohol dehydrogenase
M1S31_07285	COG0439	Biotin carboxylase
M1S31_07290	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S31_07310	COG0864	Transcriptional regulator
M1S31_07320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S31_07325	COG1116	anion transmembrane transporter activity
M1S31_07445	COG0590	tRNA wobble adenosine to inosine editing
M1S31_07450	COG2807	transmembrane transport
M1S31_07465	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1S31_07480	COG0789	Transcriptional regulator
M1S31_07490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S31_07510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S31_07520	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S31_07535	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_07540	COG0531	amino acid
M1S31_07545	COG1760	l-serine dehydratase
M1S31_07550	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_07550	COG2030	dehydratase
M1S31_07555	COG3396	Phenylacetate-CoA oxygenase
M1S31_07560	COG3460	Phenylacetate-CoA oxygenase
M1S31_07565	COG3396	Phenylacetate-CoA oxygenase
M1S31_07570	COG2151	metal-sulfur cluster biosynthetic enzyme
M1S31_07575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S31_07580	COG1024	Enoyl-CoA hydratase
M1S31_07585	COG1024	Enoyl-CoA hydratase
M1S31_07590	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S31_07595	COG0183	Belongs to the thiolase family
M1S31_07600	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
M1S31_07605	COG3327	negative regulation of DNA-templated transcription, initiation
M1S31_07615	COG2050	protein possibly involved in aromatic compounds catabolism
M1S31_07650	COG0753	catalase activity
M1S31_07655	COG3038	cytochrome b561
M1S31_07675	COG2267	carboxylic ester hydrolase activity
M1S31_07680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S31_07685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S31_07690	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_07700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1S31_07710	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_07715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1S31_07720	COG0583	DNA-binding transcription factor activity
M1S31_07730	COG1414	Transcriptional regulator
M1S31_07735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S31_07745	COG1840	ABC-type Fe3 transport system, periplasmic component
M1S31_07750	COG3842	ATPase activity
M1S31_07765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1S31_07770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1S31_07775	COG2814	Major facilitator Superfamily
M1S31_07780	COG1960	acyl-CoA dehydrogenase activity
M1S31_07795	COG1024	Enoyl-CoA hydratase
M1S31_07805	COG2814	Major facilitator Superfamily
M1S31_07815	COG0183	Belongs to the thiolase family
M1S31_07820	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S31_07825	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_07830	COG1024	Enoyl-CoA hydratase
M1S31_07835	COG1960	acyl-CoA dehydrogenase activity
M1S31_07840	COG2814	Major facilitator Superfamily
M1S31_07845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S31_07850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S31_07860	COG2814	Major facilitator Superfamily
M1S31_07870	COG1960	acyl-CoA dehydrogenase activity
M1S31_07885	COG0583	DNA-binding transcription factor activity
M1S31_07895	COG4770	biotin carboxylase activity
M1S31_07900	COG1024	Enoyl-CoA hydratase
M1S31_07905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1S31_07910	COG1960	acyl-CoA dehydrogenase activity
M1S31_07915	COG1309	transcriptional regulator
M1S31_07920	COG0318	PFAM AMP-dependent synthetase and ligase
M1S31_07945	COG0583	DNA-binding transcription factor activity
M1S31_07995	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_08015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M1S31_08035	COG0784	Response regulator, receiver
M1S31_08035	COG2205	protein histidine kinase activity
M1S31_08055	COG0765	amino acid transport
M1S31_08060	COG0765	amino acid transport
M1S31_08065	COG1126	abc transporter atp-binding protein
M1S31_08070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S31_08075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S31_08090	COG1280	lysine exporter protein (LysE YggA)
M1S31_08100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1S31_08105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1S31_08110	COG1045	serine acetyltransferase
M1S31_08125	COG0583	DNA-binding transcription factor activity
M1S31_08130	COG0625	glutathione transferase activity
M1S31_08135	COG0625	glutathione transferase activity
M1S31_08140	COG0583	DNA-binding transcription factor activity
M1S31_08150	COG1346	cytolysis
M1S31_08170	COG2814	Major facilitator Superfamily
M1S31_08180	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
M1S31_08185	COG3052	prosthetic group binding
M1S31_08205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1S31_08225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S31_08235	COG1294	oxidase, subunit
M1S31_08240	COG1271	oxidase subunit
M1S31_08260	COG0477	Major facilitator Superfamily
M1S31_08270	COG4521	taurine ABC transporter
M1S31_08275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
M1S31_08280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S31_08285	COG2175	clavaminate synthase activity
M1S31_08295	COG1953	Uracil, thiamine, allantoin
M1S31_08305	COG0583	DNA-binding transcription factor activity
M1S31_08315	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1S31_08330	COG0640	Transcriptional regulator
M1S31_08335	COG0798	PFAM Bile acid sodium symporter
M1S31_08340	COG0583	DNA-binding transcription factor activity
M1S31_08355	COG3634	alkyl hydroperoxide reductase activity
M1S31_08395	COG0436	Aminotransferase
M1S31_08405	COG0386	Belongs to the glutathione peroxidase family
M1S31_08445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1S31_08470	COG0012	GTP binding
M1S31_08475	COG2011	ABC-type metal ion transport system permease component
M1S31_08480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1S31_08490	COG1464	Belongs to the NlpA lipoprotein family
M1S31_08520	COG0765	amino acid transport
M1S31_08525	COG0765	amino acid transport
M1S31_08530	COG1126	abc transporter atp-binding protein
M1S31_08545	COG1522	sequence-specific DNA binding
M1S31_08560	COG1309	transcriptional regulator
M1S31_08580	COG0583	DNA-binding transcription factor activity
M1S31_08590	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1S31_08600	COG0697	spore germination
M1S31_08625	COG3121	Chaperone
M1S31_08630	COG3539	Fimbrial protein
M1S31_08655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M1S31_08655	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M1S31_08700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M1S31_08710	COG2353	YceI-like domain
M1S31_08720	COG3698	Phosphodiester glycosidase
M1S31_08735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1S31_08750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1S31_08755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1S31_08775	COG1132	(ABC) transporter
M1S31_08780	COG3122	Protein conserved in bacteria
M1S31_08785	COG3619	membrane
M1S31_08795	COG0640	Transcriptional regulator
M1S31_08805	COG2850	peptidyl-arginine hydroxylation
M1S31_08810	COG0424	maF-like protein
M1S31_08830	COG0191	fructose-bisphosphate aldolase activity
M1S31_08835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1S31_08850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1S31_08860	COG1192	Involved in chromosome partitioning
M1S31_08865	COG1475	DNA binding
M1S31_08870	COG0811	peptide transport
M1S31_08880	COG1132	(ABC) transporter
M1S31_08885	COG1663	tetraacyldisaccharide 4'-kinase activity
M1S31_08905	COG0084	hydrolase, TatD family'
M1S31_08970	COG0776	regulation of translation
M1S31_09000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M1S31_09005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M1S31_09065	COG0339	signal peptide processing
M1S31_09075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1S31_09110	COG0702	epimerase
M1S31_09115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1S31_09145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1S31_09175	COG0316	Belongs to the HesB IscA family
M1S31_09180	COG0822	iron-sulfur transferase activity
M1S31_09205	COG0776	regulation of translation
M1S31_09210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1S31_09215	COG2207	Transcriptional regulator
M1S31_09220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1S31_09225	COG1960	acyl-CoA dehydrogenase activity
M1S31_09230	COG1960	acyl-CoA dehydrogenase activity
M1S31_09245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1S31_09265	COG4264	IucA IucC family
M1S31_09270	COG4264	IucA IucC family
M1S31_09310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1S31_09325	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
M1S31_09345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M1S31_09350	COG0730	response to heat
M1S31_09370	COG4773	Receptor
M1S31_09375	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S31_09390	COG1131	(ABC) transporter
M1S31_09395	COG0842	Transport permease protein
M1S31_09400	COG0842	Transport permease protein
M1S31_09455	COG2226	methyltransferase
M1S31_09480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M1S31_09515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1S31_09525	COG0133	tryptophan synthase activity
M1S31_09540	COG3706	GGDEF domain
M1S31_09555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1S31_09560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1S31_09565	COG0022	dehydrogenase e1 component
M1S31_09570	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1S31_09575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S31_09585	COG1063	alcohol dehydrogenase
M1S31_09590	COG3781	membrane
M1S31_09600	COG3453	Protein conserved in bacteria
M1S31_09600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S31_09615	COG0730	response to heat
M1S31_09630	COG3708	Transcriptional regulator
M1S31_09630	COG2207	Transcriptional regulator
M1S31_09635	COG1733	regulation of RNA biosynthetic process
M1S31_09640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1S31_09650	COG2188	Transcriptional regulator
M1S31_09665	COG4521	taurine ABC transporter
M1S31_09670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S31_09690	COG0477	Major facilitator Superfamily
M1S31_09700	COG1027	Aspartate ammonia-lyase
M1S31_09715	COG0583	DNA-binding transcription factor activity
M1S31_09720	COG0583	DNA-binding transcription factor activity
M1S31_09725	COG0183	Belongs to the thiolase family
M1S31_09730	COG2031	fatty acid transporter
M1S31_09735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S31_09745	COG0583	DNA-binding transcription factor activity
M1S31_09755	COG2610	gluconate transmembrane transporter activity
M1S31_09760	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_09770	COG2207	Transcriptional regulator
M1S31_09785	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_09810	COG0543	2 iron, 2 sulfur cluster binding
M1S31_09810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S31_09815	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1S31_09820	COG4638	Rieske (2fe-2S)
M1S31_09830	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1S31_09835	COG4149	molybdate abc transporter
M1S31_09840	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
M1S31_09845	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_09850	COG1535	isochorismatase
M1S31_09850	COG3433	isochorismatase activity
M1S31_09910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1S31_09925	COG0753	catalase activity
M1S31_09935	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
M1S31_09965	COG3539	Fimbrial protein
M1S31_09985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S31_10005	COG2072	flavoprotein involved in K transport
M1S31_10015	COG1538	Outer membrane efflux protein
M1S31_10020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1S31_10025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S31_10030	COG0745	RESPONSE REGULATOR receiver
M1S31_10035	COG2205	protein histidine kinase activity
M1S31_10050	COG2207	Transcriptional regulator
M1S31_10065	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_10115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
M1S31_10235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1S31_10255	COG1120	ATPase activity
M1S31_10260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1S31_10270	COG1064	alcohol dehydrogenase
M1S31_10285	COG2207	Transcriptional regulator
M1S31_10290	COG2084	Dehydrogenase
M1S31_10300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1S31_10305	COG0583	DNA-binding transcription factor activity
M1S31_10315	COG0129	dihydroxy-acid dehydratase activity
M1S31_10335	COG1566	PFAM secretion protein HlyD family protein
M1S31_10370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1S31_10400	COG0583	DNA-binding transcription factor activity
M1S31_10415	COG2188	Transcriptional regulator
M1S31_10445	COG3210	domain, Protein
M1S31_10450	COG2831	hemolysin activation secretion protein
M1S31_10460	COG1473	amidohydrolase
M1S31_10470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S31_10470	COG0475	glutathione-regulated potassium exporter activity
M1S31_10480	COG0583	DNA-binding transcription factor activity
M1S31_10485	COG1335	isochorismatase
M1S31_10495	COG1309	transcriptional regulator
M1S31_10525	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1S31_10535	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S31_10535	COG1902	pentaerythritol trinitrate reductase activity
M1S31_10540	COG1846	Transcriptional regulator
M1S31_10560	COG0753	catalase activity
M1S31_10575	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_10590	COG3162	membrane
M1S31_10600	COG3829	transcription factor binding
M1S31_10605	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_10610	COG1960	acyl-CoA dehydrogenase activity
M1S31_10630	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_10650	COG2186	Transcriptional regulator
M1S31_10660	COG0583	DNA-binding transcription factor activity
M1S31_10665	COG4948	Mandelate Racemase Muconate Lactonizing
M1S31_10670	COG4829	muconolactone delta-isomerase
M1S31_10680	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S31_10685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S31_10690	COG0183	Belongs to the thiolase family
M1S31_10695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S31_10705	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_10715	COG3733	amine oxidase
M1S31_10725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S31_10735	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_10745	COG4638	Rieske (2fe-2S)
M1S31_10765	COG0154	amidase activity
M1S31_10775	COG2814	Major facilitator Superfamily
M1S31_10800	COG1960	acyl-CoA dehydrogenase activity
M1S31_10805	COG0583	DNA-binding transcription factor activity
M1S31_10810	COG1414	Transcriptional regulator
M1S31_10825	COG2391	methyltransferase activity
M1S31_10835	COG4993	Dehydrogenase
M1S31_10840	COG3659	wide pore channel activity
M1S31_10845	COG3420	alginic acid biosynthetic process
M1S31_10850	COG0710	3-dehydroquinate dehydratase activity
M1S31_10855	COG3485	protocatechuate 3,4-dioxygenase
M1S31_10860	COG3485	protocatechuate 3,4-dioxygenase
M1S31_10865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1S31_10870	COG2271	Major facilitator Superfamily
M1S31_10875	COG0596	Alpha beta hydrolase
M1S31_10880	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1S31_10885	COG0183	Belongs to the thiolase family
M1S31_10905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M1S31_10910	COG2323	membrane
M1S31_10955	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S31_10955	COG1902	pentaerythritol trinitrate reductase activity
M1S31_10980	COG0542	response to heat
M1S31_10985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M1S31_11015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1S31_11020	COG0569	domain protein
M1S31_11025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1S31_11040	COG4774	siderophore transport
M1S31_11045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1S31_11055	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1S31_11070	COG1294	oxidase, subunit
M1S31_11075	COG4890	Cyd operon protein YbgT
M1S31_11090	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M1S31_11100	COG0552	protein localization to endoplasmic reticulum
M1S31_11125	COG0516	GMP reductase activity
M1S31_11125	COG0517	IMP dehydrogenase activity
M1S31_11130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1S31_11135	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M1S31_11145	COG0583	DNA-binding transcription factor activity
M1S31_11150	COG0024	Methionine aminopeptidase
M1S31_11180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M1S31_11180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1S31_11185	COG1105	Belongs to the carbohydrate kinase PfkB family
M1S31_11190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1S31_11190	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M1S31_11190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1S31_11210	COG3300	MHYT domain
M1S31_11210	COG5001	Diguanylate cyclase
M1S31_11225	COG2135	peptidase activity
M1S31_11230	COG0659	secondary active sulfate transmembrane transporter activity
M1S31_11250	COG1113	amino acid transport
M1S31_11260	COG1522	sequence-specific DNA binding
M1S31_11285	COG1011	Hydrolase
M1S31_11290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1S31_11300	COG2137	regulation of response to DNA damage stimulus
M1S31_11315	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S31_11350	COG0575	Belongs to the CDS family
M1S31_11355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1S31_11375	COG3852	Histidine kinase
M1S31_11380	COG2204	response regulator
M1S31_11445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1S31_11450	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M1S31_11470	COG0697	spore germination
M1S31_11475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S31_11485	COG0303	'Molybdopterin
M1S31_11490	COG0315	cyclic pyranopterin monophosphate synthase activity
M1S31_11490	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1S31_11505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M1S31_11510	COG0243	molybdopterin cofactor binding
M1S31_11520	COG0243	molybdopterin cofactor binding
M1S31_11525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S31_11530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S31_11530	COG2146	nitrite reductase [NAD(P)H] activity
M1S31_11540	COG0745	RESPONSE REGULATOR receiver
M1S31_11545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S31_11545	COG1116	anion transmembrane transporter activity
M1S31_11565	COG0511	ligase activity, forming carbon-carbon bonds
M1S31_11580	COG2814	Major facilitator Superfamily
M1S31_11650	COG0739	heme binding
M1S31_11650	COG0741	lytic transglycosylase activity
M1S31_11650	COG1196	nuclear chromosome segregation
M1S31_11790	COG5410	chromosome segregation
M1S31_11970	COG0069	glutamate synthase activity
M1S31_11990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1S31_12000	COG1454	alcohol dehydrogenase
M1S31_12005	COG0824	Thioesterase
M1S31_12015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1S31_12030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1S31_12035	COG2030	dehydratase
M1S31_12045	COG0183	Belongs to the thiolase family
M1S31_12055	COG0583	DNA-binding transcription factor activity
M1S31_12060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M1S31_12070	COG1522	sequence-specific DNA binding
M1S31_12075	COG3135	benzoate transporter
M1S31_12085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1S31_12110	COG0589	response to stress
M1S31_12115	COG0488	(ABC) transporter
M1S31_12135	COG4773	Receptor
M1S31_12170	COG0668	transmembrane transport
M1S31_12180	COG1309	transcriptional regulator
M1S31_12200	COG1605	Chorismate mutase
M1S31_12210	COG4221	oxidoreductase activity
M1S31_12220	COG0308	aminopeptidase N
M1S31_12240	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M1S31_12250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1S31_12255	COG1454	alcohol dehydrogenase
M1S31_12275	COG0531	amino acid
M1S31_12280	COG4303	Ethanolamine ammonia lyase large subunit
M1S31_12285	COG4302	ethanolamine ammonia-lyase activity
M1S31_12290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1S31_12290	COG0519	Catalyzes the synthesis of GMP from XMP
M1S31_12295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1S31_12305	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S31_12320	COG0697	spore germination
M1S31_12325	COG1923	regulation of RNA biosynthetic process
M1S31_12335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M1S31_12340	COG0802	atpase or kinase
M1S31_12360	COG1187	pseudouridine synthase activity
M1S31_12375	COG0583	DNA-binding transcription factor activity
M1S31_12390	COG2814	Major facilitator Superfamily
M1S31_12395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1S31_12420	COG0729	surface antigen
M1S31_12440	COG0174	glutamine synthetase
M1S31_12445	COG0745	RESPONSE REGULATOR receiver
M1S31_12450	COG2205	protein histidine kinase activity
M1S31_12460	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M1S31_12465	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M1S31_12490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S31_12495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S31_12500	COG1960	acyl-CoA dehydrogenase activity
M1S31_12515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S31_12520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S31_12540	COG0583	DNA-binding transcription factor activity
M1S31_12555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S31_12565	COG3658	cytochrome
M1S31_12570	COG1215	transferase activity, transferring glycosyl groups
M1S31_12575	COG1649	PFAM Uncharacterised BCR, COG1649
M1S31_12575	COG0726	polysaccharide deacetylase
M1S31_12600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1S31_12605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1S31_12615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M1S31_12640	COG0305	Participates in initiation and elongation during chromosome replication
M1S31_12645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1S31_12655	COG1305	Transglutaminase-like
M1S31_12665	COG2308	Evidence 4 Homologs of previously reported genes of
M1S31_12695	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M1S31_12700	COG0138	bifunctional purine biosynthesis protein purh
M1S31_12705	COG0151	Belongs to the GarS family
M1S31_12710	COG1464	Belongs to the NlpA lipoprotein family
M1S31_12715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1S31_12720	COG2011	ABC-type metal ion transport system permease component
M1S31_12725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S31_12735	COG1301	dicarboxylic acid transport
M1S31_12855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1S31_12905	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_12925	COG0531	amino acid
M1S31_12935	COG1113	amino acid transport
M1S31_12975	COG3209	COG3209 Rhs family protein
M1S31_13005	COG4269	membrane
M1S31_13020	COG1902	pentaerythritol trinitrate reductase activity
M1S31_13020	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S31_13030	COG5001	Diguanylate cyclase
M1S31_13030	COG4251	negative regulation of phosphorylation
M1S31_13030	COG3706	GGDEF domain
M1S31_13030	COG2203	Gaf domain
M1S31_13040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S31_13060	COG4172	Belongs to the ABC transporter superfamily
M1S31_13065	COG4239	(ABC) transporter, permease
M1S31_13070	COG4174	ABC transporter (Permease)
M1S31_13080	COG0741	lytic transglycosylase activity
M1S31_13080	COG0741	lytic transglycosylase activity
M1S31_13080	COG1388	LysM domain
M1S31_13080	COG1388	LysM domain
M1S31_13085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S31_13125	COG0583	DNA-binding transcription factor activity
M1S31_13130	COG1279	arginine transmembrane transporter activity
M1S31_13150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S31_13155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S31_13160	COG0006	proline dipeptidase activity
M1S31_13245	COG0741	lytic transglycosylase activity
M1S31_13245	COG0739	heme binding
M1S31_13245	COG1196	nuclear chromosome segregation
M1S31_13305	COG4695	Portal protein
M1S31_13405	COG0305	Participates in initiation and elongation during chromosome replication
M1S31_13420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M1S31_13475	COG2194	sulfuric ester hydrolase activity
M1S31_13520	COG0739	heme binding
M1S31_13845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1S31_13870	COG3384	dioxygenase
M1S31_13880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1S31_13885	COG2878	Part of a membrane complex involved in electron transport
M1S31_13890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1S31_13915	COG0768	penicillin binding
M1S31_13920	COG0742	ribosomal rna small subunit methyltransferase
M1S31_13945	COG0804	urea catabolic process
M1S31_13985	COG1253	flavin adenine dinucleotide binding
M1S31_13990	COG2851	Citrate transporter
M1S31_14040	COG1773	rubredoxin
M1S31_14045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S31_14055	COG0583	DNA-binding transcription factor activity
M1S31_14080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M1S31_14085	COG4181	ATPase activity
M1S31_14130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
M1S31_14150	COG0306	phosphate transporter
M1S31_14160	COG3958	Transketolase
M1S31_14165	COG3959	Transketolase, thiamine diphosphate binding domain
M1S31_14170	COG2271	Major facilitator Superfamily
M1S31_14175	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_14180	COG0583	DNA-binding transcription factor activity
M1S31_14195	COG2223	nitrite transmembrane transporter activity
M1S31_14200	COG2207	Transcriptional regulator
M1S31_14205	COG2066	Belongs to the glutaminase family
M1S31_14210	COG0242	peptide deformylase activity
M1S31_14215	COG0477	Major facilitator Superfamily
M1S31_14225	COG0028	Belongs to the TPP enzyme family
M1S31_14240	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_14245	COG2267	carboxylic ester hydrolase activity
M1S31_14255	COG2271	Major facilitator Superfamily
M1S31_14260	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S31_14270	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_14290	COG1414	Transcriptional regulator
M1S31_14305	COG1024	Enoyl-CoA hydratase
M1S31_14315	COG1215	transferase activity, transferring glycosyl groups
M1S31_14320	COG0726	polysaccharide deacetylase
M1S31_14320	COG1649	PFAM Uncharacterised BCR, COG1649
M1S31_14330	COG4681	YaeQ
M1S31_14340	COG0523	cobalamin synthesis protein
M1S31_14350	COG1607	acyl-coa hydrolase
M1S31_14360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S31_14365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S31_14370	COG1309	transcriptional regulator
M1S31_14395	COG2040	homocysteine
M1S31_14400	COG0531	amino acid
M1S31_14455	COG1595	DNA-templated transcription, initiation
M1S31_14465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S31_14470	COG0477	Major facilitator Superfamily
M1S31_14490	COG0084	hydrolase, TatD family'
M1S31_14525	COG0629	single-stranded DNA binding
M1S31_14580	COG0582	viral genome integration into host DNA
M1S31_14610	COG1061	Type III restriction enzyme res subunit
M1S31_14620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1S31_14625	COG1192	Involved in chromosome partitioning
M1S31_14635	COG1061	Type III restriction enzyme res subunit
M1S31_14725	COG0592	DNA-directed DNA polymerase activity
M1S31_14765	COG2026	Addiction module toxin, RelE StbE family
M1S31_14915	COG3755	Protein conserved in bacteria
M1S31_14960	COG1484	DNA-dependent DNA replication
M1S31_15050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S31_15120	COG0405	Gamma-glutamyltransferase
M1S31_15125	COG2814	Major facilitator Superfamily
M1S31_15135	COG2050	protein possibly involved in aromatic compounds catabolism
M1S31_15150	COG1090	epimerase
M1S31_15170	COG0420	3'-5' exonuclease activity
M1S31_15195	COG0735	belongs to the Fur family
M1S31_15200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M1S31_15220	COG0121	glutamine amidotransferase
M1S31_15235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S31_15245	COG0210	DNA helicase
M1S31_15250	COG2885	chlorophyll binding
M1S31_15255	COG0204	Acyl-transferase
M1S31_15270	COG2894	cell division
M1S31_15295	COG1280	lysine exporter protein (LysE YggA)
M1S31_15300	COG1674	ftsk spoiiie
M1S31_15300	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M1S31_15305	COG0492	ferredoxin-NADP+ reductase activity
M1S31_15310	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
M1S31_15320	COG0456	acetyltransferase
M1S31_15365	COG1981	membrane
M1S31_15380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M1S31_15380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1S31_15400	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_15410	COG0657	acetylesterase activity
M1S31_15420	COG0473	3-isopropylmalate dehydrogenase activity
M1S31_15425	COG0583	DNA-binding transcription factor activity
M1S31_15445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1S31_15470	COG0564	pseudouridine synthase activity
M1S31_15480	COG0358	DNA primase activity
M1S31_15495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
M1S31_15525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1S31_15555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M1S31_15565	COG0352	thiamine-phosphate diphosphorylase activity
M1S31_15565	COG0351	phosphomethylpyrimidine kinase
M1S31_15565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1S31_15570	COG1652	LysM domain
M1S31_15595	COG1399	metal-binding, possibly nucleic acid-binding protein
M1S31_15600	COG3101	peptidyl-lysine hydroxylation
M1S31_15605	COG0009	L-threonylcarbamoyladenylate synthase
M1S31_15610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M1S31_15615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M1S31_15630	COG4106	trans-aconitate 2-methyltransferase activity
M1S31_15645	COG0596	Alpha beta hydrolase
M1S31_15645	COG2226	methyltransferase
M1S31_15645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S31_15650	COG1877	trehalose-phosphatase activity
M1S31_15655	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
M1S31_15660	COG2223	nitrite transmembrane transporter activity
M1S31_15680	COG1196	nuclear chromosome segregation
M1S31_15690	COG0730	response to heat
M1S31_15705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1S31_15715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1S31_15775	COG0489	protein tyrosine kinase activity
M1S31_15785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S31_15785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S31_15815	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M1S31_15820	COG2081	HI0933 family
M1S31_15830	COG0668	transmembrane transport
M1S31_15850	COG0583	DNA-binding transcription factor activity
M1S31_15870	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1S31_15905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M1S31_15945	COG0745	RESPONSE REGULATOR receiver
M1S31_15965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1S31_15975	COG2205	protein histidine kinase activity
M1S31_16045	COG4993	Dehydrogenase
M1S31_16070	COG0384	phenazine biosynthesis protein PhzF
M1S31_16095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S31_16110	COG0583	DNA-binding transcription factor activity
M1S31_16140	COG0583	DNA-binding transcription factor activity
M1S31_16155	COG0583	DNA-binding transcription factor activity
M1S31_16160	COG1053	succinate dehydrogenase
M1S31_16170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M1S31_16175	COG2814	Major facilitator Superfamily
M1S31_16180	COG1960	acyl-CoA dehydrogenase activity
M1S31_16185	COG0583	DNA-binding transcription factor activity
M1S31_16190	COG1063	alcohol dehydrogenase
M1S31_16220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M1S31_16225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1S31_16230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1S31_16245	COG3667	copper resistance
M1S31_16250	COG2132	Multicopper oxidase
M1S31_16260	COG0561	phosphatase activity
M1S31_16265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1S31_16290	COG1214	PFAM Peptidase M22, glycoprotease
M1S31_16340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1S31_16350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1S31_16355	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M1S31_16360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M1S31_16420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1S31_16430	COG1846	Transcriptional regulator
M1S31_16435	COG1764	response to oxidative stress
M1S31_16475	COG0037	tRNA processing
M1S31_16485	COG0248	Ppx GppA phosphatase
M1S31_16515	COG0072	phenylalanine-tRNA ligase activity
M1S31_16560	COG1238	metal cluster binding
M1S31_16565	COG0625	glutathione transferase activity
M1S31_16580	COG0318	PFAM AMP-dependent synthetase and ligase
M1S31_16585	COG3028	Belongs to the UPF0307 family
M1S31_16590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1S31_16610	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1S31_16615	COG0617	tRNA 3'-terminal CCA addition
M1S31_16620	COG1555	photosystem II stabilization
M1S31_16625	COG3956	TIGRFAM MazG family protein
M1S31_16635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1S31_16655	COG0784	Response regulator, receiver
M1S31_16655	COG5002	protein histidine kinase activity
M1S31_16655	COG2205	protein histidine kinase activity
M1S31_16660	COG1024	Enoyl-CoA hydratase
M1S31_16665	COG2084	Dehydrogenase
M1S31_16670	COG3622	Belongs to the hyi family
M1S31_16700	COG0697	spore germination
M1S31_16710	COG2814	Major facilitator Superfamily
M1S31_16715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1S31_16725	COG0583	DNA-binding transcription factor activity
M1S31_16735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1S31_16750	COG0084	hydrolase, TatD family'
M1S31_16765	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M1S31_16795	COG0440	acetolactate synthase activity
M1S31_16800	COG0028	Belongs to the TPP enzyme family
M1S31_16825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S31_16830	COG0577	efflux transmembrane transporter activity
M1S31_16830	COG1136	(ABC) transporter
M1S31_16835	COG1538	Outer membrane efflux protein
M1S31_16850	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M1S31_16855	COG1162	GTPase activity
M1S31_16865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M1S31_16885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1S31_16890	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_16930	COG2986	histidine ammonia-lyase
M1S31_16945	COG0318	PFAM AMP-dependent synthetase and ligase
M1S31_16955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1S31_17000	COG1426	Protein conserved in bacteria
M1S31_17035	COG0793	Belongs to the peptidase S41A family
M1S31_17050	COG2267	carboxylic ester hydrolase activity
M1S31_17060	COG1012	belongs to the aldehyde dehydrogenase family
M1S31_17065	COG3265	gluconokinase activity
M1S31_17075	COG0800	Aldolase
M1S31_17085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M1S31_17090	COG0857	belongs to the CobB CobQ family
M1S31_17090	COG0280	phosphate acetyltransferase
M1S31_17095	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M1S31_17095	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M1S31_17115	COG0740	serine-type endopeptidase activity
M1S31_17125	COG4774	siderophore transport
M1S31_17135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1S31_17145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S31_17145	COG2813	Specifically methylates the guanine in position
M1S31_17245	COG0788	formyltetrahydrofolate deformylase activity
M1S31_17270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S31_17270	COG4651	solute:proton antiporter activity
M1S31_17290	COG0724	RNA recognition motif
M1S31_17295	COG0210	DNA helicase
M1S31_17320	COG1733	regulation of RNA biosynthetic process
M1S31_17330	COG2900	Belongs to the SlyX family
M1S31_17335	COG0488	(ABC) transporter
M1S31_17340	COG1280	lysine exporter protein (LysE YggA)
M1S31_17345	COG1560	Kdo2-lipid A biosynthetic process
M1S31_17355	COG1301	dicarboxylic acid transport
M1S31_17410	COG0473	3-isopropylmalate dehydrogenase activity
M1S31_17475	COG0583	DNA-binding transcription factor activity
M1S31_17485	COG0625	glutathione transferase activity
M1S31_17490	COG2378	regulation of single-species biofilm formation
M1S31_17495	COG0546	phosphoglycolate phosphatase activity
M1S31_17505	COG1530	ribonuclease E activity
M1S31_17510	COG0318	PFAM AMP-dependent synthetase and ligase
M1S31_17525	COG0583	DNA-binding transcription factor activity
M1S31_17530	COG4221	oxidoreductase activity
M1S31_17535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1S31_17545	COG0534	Mate efflux family protein
M1S31_17560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
M1S31_17600	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
M1S31_17605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S31_17620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1S31_17630	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
M1S31_17630	COG0644	oxidoreductase
M1S31_17635	COG0425	Belongs to the sulfur carrier protein TusA family
M1S31_17640	COG4535	Mg2 and Co2 transporter CorC
M1S31_17650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S31_17670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1S31_17675	COG0475	glutathione-regulated potassium exporter activity
M1S31_17675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S31_17680	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M1S31_17690	COG0484	heat shock protein binding
M1S31_17695	COG0789	Transcriptional regulator
M1S31_17700	COG0598	Magnesium transport protein CorA
M1S31_17715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1S31_17720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1S31_17725	COG1074	ATP-dependent DNA helicase activity
M1S31_17730	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M1S31_17750	COG2226	methyltransferase
M1S31_17765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S31_17770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M1S31_17785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1S31_17785	COG2111	Na H antiporter
M1S31_17790	COG1006	Multisubunit Na H antiporter MnhC subunit
M1S31_17795	COG0651	ATP synthesis coupled electron transport
M1S31_17800	COG1863	multisubunit Na H antiporter MnhE subunit
M1S31_17805	COG2212	antiporter activity
M1S31_17810	COG1320	monovalent cation:proton antiporter activity
M1S31_17825	COG0195	Participates in both transcription termination and antitermination
M1S31_17875	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1S31_17880	COG0237	dephospho-CoA kinase activity
M1S31_17890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1S31_17905	COG0497	DNA recombination
M1S31_17915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M1S31_17945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1S31_17945	COG2169	Transcriptional regulator
M1S31_17950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1S31_18015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1S31_18030	COG0326	Molecular chaperone. Has ATPase activity
M1S31_18045	COG2056	Na+-H+ antiporter family
M1S31_18050	COG0596	Alpha beta hydrolase
M1S31_18145	COG0546	phosphoglycolate phosphatase activity
M1S31_18150	COG1716	ATPase activity
M1S31_18195	COG0181	hydroxymethylbilane synthase activity
M1S31_18205	COG3275	phosphorelay sensor kinase activity
M1S31_18225	COG1538	Outer membrane efflux protein
M1S31_18230	COG0697	spore germination
M1S31_18255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1S31_18260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1S31_18265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1S31_18270	COG0772	Belongs to the SEDS family
M1S31_18295	COG4974	Belongs to the 'phage' integrase family
M1S31_18300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S31_18310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M1S31_18320	COG2197	response regulator
M1S31_18335	COG0793	Belongs to the peptidase S41A family
M1S31_18340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M1S31_18345	COG0795	lipopolysaccharide-transporting ATPase activity
M1S31_18385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1S31_18385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1S31_18395	COG0004	ammonium transporteR
M1S31_18400	COG0347	Belongs to the P(II) protein family
M1S31_18460	COG0659	secondary active sulfate transmembrane transporter activity
M1S31_18465	COG0589	response to stress
M1S31_18500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S31_18510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S31_18530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M1S31_18545	COG0318	PFAM AMP-dependent synthetase and ligase
M1S31_18555	COG0477	Major facilitator Superfamily
M1S31_18560	COG2860	membrane
M1S31_18570	COG1253	flavin adenine dinucleotide binding
M1S31_18590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1S31_18630	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1S31_18640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1S31_18710	COG0758	DNA mediated transformation
M1S31_18720	COG0697	spore germination
M1S31_18725	COG1309	transcriptional regulator
M1S31_18740	COG0386	Belongs to the glutathione peroxidase family
M1S31_18805	COG1121	(ABC) transporter
M1S31_18810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1S31_18815	COG1280	lysine exporter protein (LysE YggA)
M1S31_18820	COG2837	iron assimilation
M1S31_18830	COG0281	malic enzyme
M1S31_18875	COG0519	Catalyzes the synthesis of GMP from XMP
M1S31_18875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1S31_18880	COG4399	Belongs to the UPF0754 family
M1S31_18885	COG2259	Doxx family
M1S31_18890	COG0586	Pfam SNARE associated Golgi protein
M1S31_18905	COG1192	Involved in chromosome partitioning
M1S31_18915	COG0271	Belongs to the BolA IbaG family
M1S31_18935	COG2267	carboxylic ester hydrolase activity
M1S31_18955	COG3321	synthase
M1S31_18955	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M1S31_18955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1S31_18955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M1S31_18960	COG1960	acyl-CoA dehydrogenase activity
M1S31_18970	COG2197	response regulator
M1S31_18980	COG3916	Acyl-homoserine-lactone synthase
M1S31_18985	COG0477	Major facilitator Superfamily
M1S31_18990	COG1024	Enoyl-CoA hydratase
M1S31_18995	COG1024	Enoyl-CoA hydratase
M1S31_19000	COG1960	acyl-CoA dehydrogenase activity
M1S31_19005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S31_19025	COG1113	amino acid transport
M1S31_19030	COG1113	amino acid transport
M1S31_19035	COG0251	oxidation-reduction process
M1S31_19075	COG0564	pseudouridine synthase activity
M1S31_19135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1S31_19150	COG1802	Transcriptional regulator
M1S31_19160	COG1448	Aminotransferase
M1S31_19165	COG0277	FAD linked oxidase domain protein
M1S31_19175	COG2186	Transcriptional regulator
M1S31_19185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S31_19190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1S31_19205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1S31_19210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1S31_19215	COG1216	Glycosyl transferase, family 2
M1S31_19245	COG2089	acid synthase
M1S31_19260	COG1083	cytidylyl-transferase
M1S31_19265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M1S31_19270	COG1086	Polysaccharide biosynthesis protein
M1S31_19275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M1S31_19280	COG1596	polysaccharide export
M1S31_19305	COG0728	peptidoglycan biosynthetic process
M1S31_19310	COG3023	N-Acetylmuramoyl-L-alanine amidase
M1S31_19370	COG0546	phosphoglycolate phosphatase activity
M1S31_19375	COG1028	Short-chain dehydrogenase reductase Sdr
M1S31_19395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S31_19400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S31_19405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S31_19410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S31_19415	COG1116	anion transmembrane transporter activity
M1S31_19420	COG1309	transcriptional regulator
M1S31_19425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M1S31_19435	COG0196	riboflavin kinase activity
M1S31_19440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1S31_19450	COG1047	Peptidyl-prolyl cis-trans
M1S31_19490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1S31_19495	COG0657	acetylesterase activity
M1S31_19515	COG0583	DNA-binding transcription factor activity
M1S31_19545	COG2951	lytic endotransglycosylase activity
M1S31_19550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1S31_19565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M1S31_19575	COG0671	phosphoesterase, PA-phosphatase related
M1S31_19580	COG0861	Integral membrane protein TerC family
M1S31_19590	COG0754	glutathionylspermidine amidase activity
M1S31_19600	COG0402	S-adenosylhomocysteine deaminase activity
M1S31_19615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S31_19620	COG1230	cation diffusion facilitator family transporter
M1S31_19635	COG0706	membrane insertase activity
M1S31_19680	COG0358	DNA primase activity
M1S31_19735	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1S31_19780	COG0587	DNA-directed DNA polymerase activity
M1S31_19795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1S31_19795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1S31_19845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1S31_19845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M1S31_19850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1S31_19890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S31_19935	COG1309	transcriptional regulator
M1S31_19945	COG1902	pentaerythritol trinitrate reductase activity
M1S31_19955	COG1979	alcohol dehydrogenase
M1S31_19970	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
M1S31_19995	COG1063	alcohol dehydrogenase
M1S31_20075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1S31_20095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system