locus-tag	class	description
M1S17_00010	COG0592	DNA-directed DNA polymerase activity
M1S17_00020	COG0187	DNA topoisomerase II activity
M1S17_00030	COG0586	Pfam SNARE associated Golgi protein
M1S17_00035	COG0488	(ABC) transporter
M1S17_00060	COG0596	Alpha beta hydrolase
M1S17_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
M1S17_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M1S17_00110	COG0733	neurotransmitter:sodium symporter activity
M1S17_00150	COG2233	PERMEase
M1S17_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S17_00200	COG2814	Major facilitator Superfamily
M1S17_00205	COG0656	L-ascorbic acid biosynthetic process
M1S17_00210	COG0583	DNA-binding transcription factor activity
M1S17_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S17_00230	COG1064	alcohol dehydrogenase
M1S17_00235	COG2818	Glycosylase
M1S17_00250	COG1194	a g-specific adenine glycosylase
M1S17_00270	COG2983	Belongs to the UPF0260 family
M1S17_00275	COG2133	pyrroloquinoline quinone binding
M1S17_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1S17_00285	COG2116	formate transmembrane transporter activity
M1S17_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S17_00310	COG1335	isochorismatase
M1S17_00315	COG0385	Bile acid
M1S17_00320	COG0534	Mate efflux family protein
M1S17_00325	COG1683	Conserved Protein
M1S17_00345	COG0625	glutathione transferase activity
M1S17_00355	COG1113	amino acid transport
M1S17_00365	COG0523	cobalamin synthesis protein
M1S17_00375	COG2188	Transcriptional regulator
M1S17_00405	COG0010	Belongs to the arginase family
M1S17_00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1S17_00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M1S17_00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1S17_00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M1S17_00545	COG0534	Mate efflux family protein
M1S17_00550	COG0436	Aminotransferase
M1S17_00555	COG2733	membrane
M1S17_00570	COG2918	glutathione biosynthetic process
M1S17_00585	COG1388	LysM domain
M1S17_00585	COG0791	NLP P60 protein
M1S17_00600	COG3150	esterase
M1S17_00610	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
M1S17_00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S17_00635	COG2233	PERMEase
M1S17_00640	COG2351	hydroxyisourate hydrolase activity
M1S17_00675	COG3706	GGDEF domain
M1S17_00690	COG1393	Belongs to the ArsC family
M1S17_00695	COG0708	Exodeoxyribonuclease III
M1S17_00715	COG0189	ligase activity
M1S17_00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1S17_00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1S17_00760	COG4942	peptidase
M1S17_00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1S17_00780	COG2119	membrane
M1S17_00800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S17_00800	COG0426	domain, Protein
M1S17_00825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1S17_00845	COG1902	pentaerythritol trinitrate reductase activity
M1S17_00850	COG1519	Transferase
M1S17_00855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1S17_00860	COG0668	transmembrane transport
M1S17_00870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S17_00875	COG1335	isochorismatase
M1S17_00880	COG1522	sequence-specific DNA binding
M1S17_00885	COG3328	transposase activity
M1S17_00910	COG2205	protein histidine kinase activity
M1S17_00910	COG2198	Histidine kinase
M1S17_00910	COG0784	Response regulator, receiver
M1S17_00915	COG3162	membrane
M1S17_00920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1S17_00930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S17_00950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1S17_00955	COG1309	transcriptional regulator
M1S17_00975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1S17_00975	COG0352	thiamine-phosphate diphosphorylase activity
M1S17_00975	COG0351	phosphomethylpyrimidine kinase
M1S17_00985	COG2814	Major facilitator Superfamily
M1S17_01000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1S17_01010	COG1113	amino acid transport
M1S17_01020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1S17_01025	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_01035	COG1335	isochorismatase
M1S17_01065	COG2814	Major facilitator Superfamily
M1S17_01070	COG0583	DNA-binding transcription factor activity
M1S17_01090	COG0667	Aldo Keto reductase
M1S17_01125	COG1733	regulation of RNA biosynthetic process
M1S17_01130	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S17_01200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1S17_01215	COG2329	Antibiotic biosynthesis monooxygenase
M1S17_01245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M1S17_01275	COG0427	acetyl-CoA hydrolase
M1S17_01300	COG0659	secondary active sulfate transmembrane transporter activity
M1S17_01305	COG4221	oxidoreductase activity
M1S17_01310	COG2873	o-acetylhomoserine
M1S17_01315	COG0488	(ABC) transporter
M1S17_01400	COG0833	amino acid
M1S17_01445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1S17_01450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1S17_01465	COG2226	methyltransferase
M1S17_01515	COG0070	glutamate synthase
M1S17_01515	COG0069	glutamate synthase activity
M1S17_01515	COG0067	glutamate synthase
M1S17_01520	COG0493	'glutamate synthase
M1S17_01530	COG1704	LemA family
M1S17_01535	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M1S17_01555	COG3307	-O-antigen
M1S17_01575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1S17_01590	COG0194	GDP metabolic process
M1S17_01640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M1S17_01660	COG5380	lipid catabolic process
M1S17_01665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M1S17_01690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1S17_01695	COG0277	FAD linked oxidase domain protein
M1S17_01705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M1S17_01710	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S17_01725	COG1289	transmembrane transporter activity
M1S17_01735	COG0628	permease
M1S17_01740	COG1192	Involved in chromosome partitioning
M1S17_01770	COG0833	amino acid
M1S17_01775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1S17_01780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1S17_01790	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_01830	COG0583	DNA-binding transcription factor activity
M1S17_01875	COG0517	IMP dehydrogenase activity
M1S17_01880	COG1983	PspC domain protein
M1S17_01890	COG1960	acyl-CoA dehydrogenase activity
M1S17_01905	COG0408	coproporphyrinogen oxidase activity
M1S17_01925	COG0513	Belongs to the DEAD box helicase family
M1S17_01935	COG1127	ABC transporter
M1S17_01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M1S17_01950	COG2854	intermembrane phospholipid transfer
M1S17_01960	COG0598	Magnesium transport protein CorA
M1S17_01970	COG0494	nUDIX hydrolase
M1S17_01975	COG1040	competence protein
M1S17_01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1S17_02000	COG1946	Acyl-CoA thioesterase
M1S17_02005	COG1301	dicarboxylic acid transport
M1S17_02020	COG1959	2 iron, 2 sulfur cluster binding
M1S17_02025	COG1017	nitric oxide dioxygenase activity
M1S17_02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S17_02030	COG0433	COG0433 Predicted ATPase
M1S17_02035	COG0626	cystathionine gamma-synthase activity
M1S17_02190	COG1960	acyl-CoA dehydrogenase activity
M1S17_02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M1S17_02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M1S17_02230	COG0339	signal peptide processing
M1S17_02235	COG0557	exoribonuclease II activity
M1S17_02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1S17_02285	COG2169	Transcriptional regulator
M1S17_02290	COG0697	spore germination
M1S17_02295	COG1295	ribonuclease BN
M1S17_02330	COG1702	phosphate starvation-inducible protein PhoH
M1S17_02340	COG0741	lytic transglycosylase activity
M1S17_02340	COG0739	heme binding
M1S17_02340	COG1196	nuclear chromosome segregation
M1S17_02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M1S17_02420	COG1960	acyl-CoA dehydrogenase activity
M1S17_02425	COG1309	transcriptional regulator
M1S17_02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1S17_02445	COG1960	acyl-CoA dehydrogenase activity
M1S17_02465	COG2969	positive regulation of protein catabolic process
M1S17_02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M1S17_02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M1S17_02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M1S17_02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1S17_02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1S17_02530	COG1408	metallophosphoesterase
M1S17_02540	COG2199	diguanylate cyclase activity
M1S17_02600	COG1607	acyl-coa hydrolase
M1S17_02630	COG2350	Protein conserved in bacteria
M1S17_02640	COG0613	PHP domain protein
M1S17_02645	COG3781	membrane
M1S17_02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1S17_02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1S17_02670	COG1862	Preprotein translocase
M1S17_02725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M1S17_02745	COG0726	polysaccharide deacetylase
M1S17_02750	COG0463	Glycosyl transferase, family 2
M1S17_02755	COG0438	transferase activity, transferring glycosyl groups
M1S17_02820	COG0625	glutathione transferase activity
M1S17_02825	COG0583	DNA-binding transcription factor activity
M1S17_02830	COG1960	acyl-CoA dehydrogenase activity
M1S17_02835	COG1960	acyl-CoA dehydrogenase activity
M1S17_02845	COG2205	protein histidine kinase activity
M1S17_02850	COG0745	RESPONSE REGULATOR receiver
M1S17_02855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M1S17_02875	COG2096	Adenosyltransferase
M1S17_02925	COG0285	dihydrofolate synthase activity
M1S17_02945	COG0450	alkyl hydroperoxide reductase
M1S17_02960	COG0477	Major facilitator Superfamily
M1S17_02965	COG1272	protein, Hemolysin III
M1S17_02995	COG0183	Belongs to the thiolase family
M1S17_03000	COG2207	Transcriptional regulator
M1S17_03020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S17_03040	COG0183	Belongs to the thiolase family
M1S17_03050	COG2885	chlorophyll binding
M1S17_03050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M1S17_03060	COG1690	Belongs to the RtcB family
M1S17_03065	COG0833	amino acid
M1S17_03075	COG2233	PERMEase
M1S17_03080	COG1217	gtp-binding protein TYPA
M1S17_03105	COG2094	Belongs to the DNA glycosylase MPG family
M1S17_03125	COG1902	pentaerythritol trinitrate reductase activity
M1S17_03140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S17_03145	COG0354	folic acid binding
M1S17_03155	COG3189	MarR family transcriptional regulator
M1S17_03160	COG2824	Alkylphosphonate utilization operon protein PhnA
M1S17_03165	COG3422	double-strand break repair
M1S17_03205	COG0840	transmembrane signaling receptor activity
M1S17_03225	COG5510	response to toxic substance
M1S17_03235	COG2832	Protein of unknown function (DUF454)
M1S17_03240	COG1376	ErfK ybiS ycfS ynhG family protein
M1S17_03280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M1S17_03290	COG1289	transmembrane transporter activity
M1S17_03295	COG2814	Major facilitator Superfamily
M1S17_03315	COG1115	amino acid carrier protein
M1S17_03320	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1S17_03325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1S17_03330	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
M1S17_03360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1S17_03370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1S17_03375	COG1077	Cell shape determining protein MreB Mrl
M1S17_03380	COG1792	Involved in formation and maintenance of cell shape
M1S17_03385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M1S17_03390	COG0424	maF-like protein
M1S17_03395	COG1530	ribonuclease E activity
M1S17_03405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S17_03415	COG0560	Phosphoserine phosphatase
M1S17_03425	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S17_03450	COG2207	Transcriptional regulator
M1S17_03470	COG1113	amino acid transport
M1S17_03475	COG2828	Protein conserved in bacteria
M1S17_03480	COG0142	geranyltranstransferase activity
M1S17_03485	COG2315	Protein conserved in bacteria
M1S17_03500	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1S17_03520	COG2194	sulfuric ester hydrolase activity
M1S17_03525	COG0745	RESPONSE REGULATOR receiver
M1S17_03540	COG0004	ammonium transporteR
M1S17_03545	COG0583	DNA-binding transcription factor activity
M1S17_03565	COG0525	valine-tRNA ligase activity
M1S17_03575	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_03585	COG0393	Putative heavy-metal-binding
M1S17_03590	COG0393	Putative heavy-metal-binding
M1S17_03595	COG1538	Outer membrane efflux protein
M1S17_03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S17_03610	COG0671	phosphoesterase, PA-phosphatase related
M1S17_03640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1S17_03655	COG1648	precorrin-2 dehydrogenase activity
M1S17_03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1S17_03660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1S17_03665	COG1733	regulation of RNA biosynthetic process
M1S17_03675	COG0531	amino acid
M1S17_03690	COG0321	lipoyl(octanoyl) transferase activity
M1S17_03695	COG2921	Belongs to the UPF0250 family
M1S17_03735	COG2009	succinate dehydrogenase
M1S17_03740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M1S17_03745	COG1053	succinate dehydrogenase
M1S17_03750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1S17_03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S17_03795	COG2354	Protein conserved in bacteria
M1S17_03800	COG2321	neutral zinc metallopeptidase
M1S17_03820	COG2843	Capsule synthesis protein
M1S17_03835	COG0589	response to stress
M1S17_03855	COG0505	Belongs to the CarA family
M1S17_03880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1S17_03885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1S17_03935	COG0477	Major facilitator Superfamily
M1S17_03940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M1S17_03955	COG1597	lipid kinase activity
M1S17_03960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1S17_03985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S17_03990	COG0584	glycerophosphoryl diester phosphodiesterase
M1S17_04010	COG0741	lytic transglycosylase activity
M1S17_04030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M1S17_04045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S17_04075	COG0778	Nitroreductase
M1S17_04090	COG1929	Belongs to the glycerate kinase type-1 family
M1S17_04095	COG0243	molybdopterin cofactor binding
M1S17_04100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1S17_04105	COG3339	Conserved Protein
M1S17_04115	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
M1S17_04130	COG1113	amino acid transport
M1S17_04140	COG0019	diaminopimelate decarboxylase activity
M1S17_04150	COG1280	lysine exporter protein (LysE YggA)
M1S17_04155	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1S17_04185	COG0463	Glycosyl transferase, family 2
M1S17_04205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S17_04240	COG4591	ABC-type transport system involved in lipoprotein release permease component
M1S17_04245	COG1136	(ABC) transporter
M1S17_04250	COG0658	competence protein
M1S17_04250	COG2333	competence protein COMEC
M1S17_04260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M1S17_04260	COG0616	signal peptide processing
M1S17_04265	COG0596	Alpha beta hydrolase
M1S17_04270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1S17_04280	COG0628	permease
M1S17_04325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1S17_04345	COG0823	Involved in the tonB-independent uptake of proteins
M1S17_04365	COG0824	Thioesterase
M1S17_04370	COG1473	amidohydrolase
M1S17_04390	COG0047	phosphoribosylformylglycinamidine synthase activity
M1S17_04390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1S17_04395	COG2814	Major facilitator Superfamily
M1S17_04405	COG1024	Enoyl-CoA hydratase
M1S17_04410	COG1051	belongs to the nudix hydrolase family
M1S17_04410	COG1056	cytidyltransferase-related domain
M1S17_04420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1S17_04435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M1S17_04450	COG4625	pathogenesis
M1S17_04455	COG0583	DNA-binding transcription factor activity
M1S17_04460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M1S17_04465	COG4208	sulfate ABC transporter
M1S17_04470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M1S17_04480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M1S17_04485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1S17_04490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1S17_04510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1S17_04525	COG0681	Belongs to the peptidase S26 family
M1S17_04540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1S17_04550	COG1381	Involved in DNA repair and RecF pathway recombination
M1S17_04555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M1S17_04565	COG4221	oxidoreductase activity
M1S17_04595	COG0436	Aminotransferase
M1S17_04615	COG0556	nucleotide-excision repair
M1S17_04670	COG2070	2-Nitropropane dioxygenase
M1S17_04700	COG1215	transferase activity, transferring glycosyl groups
M1S17_04715	COG0415	Belongs to the DNA photolyase family
M1S17_04725	COG1252	NADH dehydrogenase
M1S17_04730	COG1686	Belongs to the peptidase S11 family
M1S17_04745	COG1187	pseudouridine synthase activity
M1S17_04770	COG0477	Major facilitator Superfamily
M1S17_04775	COG0583	DNA-binding transcription factor activity
M1S17_04780	COG1823	symporter activity
M1S17_04790	COG0612	Peptidase, M16
M1S17_04815	COG0352	thiamine-phosphate diphosphorylase activity
M1S17_04850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S17_04865	COG1309	transcriptional regulator
M1S17_04875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1S17_04880	COG0076	glutamate decarboxylase activity
M1S17_04890	COG1522	sequence-specific DNA binding
M1S17_04895	COG3961	Belongs to the TPP enzyme family
M1S17_04900	COG1113	amino acid transport
M1S17_04905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1S17_04910	COG0573	inorganic phosphate transmembrane transporter activity
M1S17_04920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M1S17_04925	COG0616	signal peptide processing
M1S17_04960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1S17_04965	COG1686	Belongs to the peptidase S11 family
M1S17_04990	COG0583	DNA-binding transcription factor activity
M1S17_04995	COG1067	ATP-dependent peptidase activity
M1S17_05040	COG1966	Carbon starvation protein
M1S17_05045	COG2879	small protein
M1S17_05080	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M1S17_05080	COG2508	Transcriptional regulator
M1S17_05100	COG1113	amino acid transport
M1S17_05105	COG0583	DNA-binding transcription factor activity
M1S17_05110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S17_05115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S17_05125	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_05135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S17_05140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
M1S17_05140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S17_05175	COG2814	Major facilitator Superfamily
M1S17_05180	COG4948	Mandelate Racemase Muconate Lactonizing
M1S17_05190	COG1309	transcriptional regulator
M1S17_05210	COG1741	Belongs to the pirin family
M1S17_05220	COG2964	Protein conserved in bacteria
M1S17_05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S17_05240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1S17_05245	COG4605	iron ion homeostasis
M1S17_05250	COG4604	ABC transporter, ATP-binding protein
M1S17_05255	COG4607	ABC-type enterochelin transport system periplasmic component
M1S17_05260	COG4774	siderophore transport
M1S17_05270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S17_05275	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1S17_05280	COG1535	isochorismatase
M1S17_05280	COG3433	isochorismatase activity
M1S17_05295	COG1132	(ABC) transporter
M1S17_05300	COG1132	(ABC) transporter
M1S17_05305	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M1S17_05315	COG1169	isochorismate synthase
M1S17_05330	COG3739	integral membrane protein
M1S17_05355	COG0302	gtp cyclohydrolase
M1S17_05365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M1S17_05395	COG0308	aminopeptidase N
M1S17_05400	COG0512	Glutamine amidotransferase of anthranilate synthase
M1S17_05415	COG0174	glutamine synthetase
M1S17_05425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
M1S17_05460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1S17_05465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1S17_05470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1S17_05490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1S17_05495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1S17_05500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
M1S17_05515	COG1960	acyl-CoA dehydrogenase activity
M1S17_05520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1S17_05525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S17_05535	COG2223	nitrite transmembrane transporter activity
M1S17_05545	COG0024	Methionine aminopeptidase
M1S17_05550	COG0052	Belongs to the universal ribosomal protein uS2 family
M1S17_05565	COG2207	Transcriptional regulator
M1S17_05590	COG2951	lytic endotransglycosylase activity
M1S17_05595	COG0772	Belongs to the SEDS family
M1S17_05610	COG0842	Transport permease protein
M1S17_05660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S17_05675	COG4215	(ABC) transporter
M1S17_05680	COG4160	amino acid transport
M1S17_05685	COG4598	ABC transporter
M1S17_05695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1S17_05700	COG0826	peptidase U32
M1S17_05705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S17_05720	COG1720	tRNA m6t6A37 methyltransferase activity
M1S17_05730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1S17_05745	COG0642	Histidine kinase
M1S17_05755	COG0494	nUDIX hydrolase
M1S17_05765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1S17_05770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M1S17_05775	COG3139	Protein of unknown function (DUF1315)
M1S17_05780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M1S17_05785	COG1301	dicarboxylic acid transport
M1S17_05790	COG1960	acyl-CoA dehydrogenase activity
M1S17_05795	COG2819	hydrolase of the alpha beta superfamily
M1S17_05805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M1S17_05815	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1S17_05820	COG1234	tRNA 3'-trailer cleavage
M1S17_05850	COG2363	Small membrane protein
M1S17_05875	COG0513	Belongs to the DEAD box helicase family
M1S17_05885	COG0778	Nitroreductase
M1S17_06115	COG1286	toxin biosynthetic process
M1S17_06140	COG4783	chaperone-mediated protein folding
M1S17_06145	COG1610	YqeY-like protein
M1S17_06245	COG3111	PFAM Bacterial OB fold (BOF) protein
M1S17_06270	COG3243	poly(R)-hydroxyalkanoic acid synthase
M1S17_06275	COG0786	glutamate:sodium symporter activity
M1S17_06285	COG2186	Transcriptional regulator
M1S17_06335	COG0477	Major facilitator Superfamily
M1S17_06365	COG2985	domain, Protein
M1S17_06375	COG2995	paraquat-inducible protein a
M1S17_06380	COG3008	intermembrane lipid transfer
M1S17_06380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M1S17_06390	COG1794	racemase activity, acting on amino acids and derivatives
M1S17_06485	COG0488	(ABC) transporter
M1S17_06490	COG3173	Aminoglycoside phosphotransferase
M1S17_06500	COG2433	Pfam Transposase IS66
M1S17_06540	COG1301	dicarboxylic acid transport
M1S17_06550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S17_06555	COG2011	ABC-type metal ion transport system permease component
M1S17_06560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1S17_06565	COG1464	Belongs to the NlpA lipoprotein family
M1S17_06570	COG0151	Belongs to the GarS family
M1S17_06575	COG0138	bifunctional purine biosynthesis protein purh
M1S17_06580	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M1S17_06610	COG2308	Evidence 4 Homologs of previously reported genes of
M1S17_06620	COG1305	Transglutaminase-like
M1S17_06630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1S17_06635	COG0305	Participates in initiation and elongation during chromosome replication
M1S17_06660	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M1S17_06670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1S17_06675	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1S17_06700	COG0726	polysaccharide deacetylase
M1S17_06700	COG1649	PFAM Uncharacterised BCR, COG1649
M1S17_06705	COG1215	transferase activity, transferring glycosyl groups
M1S17_06710	COG3658	cytochrome
M1S17_06720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S17_06735	COG0583	DNA-binding transcription factor activity
M1S17_06755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S17_06760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S17_06775	COG1960	acyl-CoA dehydrogenase activity
M1S17_06780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S17_06785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S17_06810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M1S17_06815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M1S17_06825	COG2205	protein histidine kinase activity
M1S17_06830	COG0745	RESPONSE REGULATOR receiver
M1S17_06835	COG0174	glutamine synthetase
M1S17_06855	COG0729	surface antigen
M1S17_06880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1S17_06885	COG2814	Major facilitator Superfamily
M1S17_06900	COG0583	DNA-binding transcription factor activity
M1S17_06915	COG1187	pseudouridine synthase activity
M1S17_06935	COG0802	atpase or kinase
M1S17_06940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M1S17_06950	COG1923	regulation of RNA biosynthetic process
M1S17_06955	COG0697	spore germination
M1S17_06970	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S17_06980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1S17_06985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1S17_06985	COG0519	Catalyzes the synthesis of GMP from XMP
M1S17_06990	COG4302	ethanolamine ammonia-lyase activity
M1S17_06995	COG4303	Ethanolamine ammonia lyase large subunit
M1S17_07000	COG0531	amino acid
M1S17_07020	COG1454	alcohol dehydrogenase
M1S17_07025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1S17_07035	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M1S17_07055	COG0308	aminopeptidase N
M1S17_07065	COG4221	oxidoreductase activity
M1S17_07075	COG1605	Chorismate mutase
M1S17_07095	COG1309	transcriptional regulator
M1S17_07105	COG0668	transmembrane transport
M1S17_07140	COG4773	Receptor
M1S17_07160	COG0488	(ABC) transporter
M1S17_07165	COG0589	response to stress
M1S17_07190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1S17_07200	COG3135	benzoate transporter
M1S17_07205	COG1522	sequence-specific DNA binding
M1S17_07215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M1S17_07220	COG0583	DNA-binding transcription factor activity
M1S17_07230	COG0183	Belongs to the thiolase family
M1S17_07240	COG2030	dehydratase
M1S17_07245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1S17_07260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1S17_07270	COG0824	Thioesterase
M1S17_07275	COG1454	alcohol dehydrogenase
M1S17_07285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1S17_07305	COG0069	glutamate synthase activity
M1S17_07475	COG5410	chromosome segregation
M1S17_07585	COG0739	heme binding
M1S17_07675	COG2814	Major facilitator Superfamily
M1S17_07690	COG0511	ligase activity, forming carbon-carbon bonds
M1S17_07710	COG1116	anion transmembrane transporter activity
M1S17_07710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S17_07715	COG0745	RESPONSE REGULATOR receiver
M1S17_07725	COG2146	nitrite reductase [NAD(P)H] activity
M1S17_07725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S17_07730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S17_07735	COG0243	molybdopterin cofactor binding
M1S17_07745	COG0243	molybdopterin cofactor binding
M1S17_07750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M1S17_07765	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1S17_07765	COG0315	cyclic pyranopterin monophosphate synthase activity
M1S17_07770	COG0303	'Molybdopterin
M1S17_07780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S17_07785	COG0697	spore germination
M1S17_07805	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M1S17_07810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1S17_07875	COG2204	response regulator
M1S17_07880	COG3852	Histidine kinase
M1S17_07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1S17_07905	COG0575	Belongs to the CDS family
M1S17_07940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S17_07955	COG2137	regulation of response to DNA damage stimulus
M1S17_07965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1S17_07970	COG1011	Hydrolase
M1S17_07995	COG1522	sequence-specific DNA binding
M1S17_08005	COG1113	amino acid transport
M1S17_08025	COG0659	secondary active sulfate transmembrane transporter activity
M1S17_08030	COG2135	peptidase activity
M1S17_08045	COG3300	MHYT domain
M1S17_08045	COG5001	Diguanylate cyclase
M1S17_08065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1S17_08065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1S17_08065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M1S17_08070	COG1105	Belongs to the carbohydrate kinase PfkB family
M1S17_08075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1S17_08075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M1S17_08105	COG0024	Methionine aminopeptidase
M1S17_08110	COG0583	DNA-binding transcription factor activity
M1S17_08120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M1S17_08125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1S17_08130	COG0516	GMP reductase activity
M1S17_08130	COG0517	IMP dehydrogenase activity
M1S17_08155	COG0552	protein localization to endoplasmic reticulum
M1S17_08165	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M1S17_08180	COG4890	Cyd operon protein YbgT
M1S17_08185	COG1294	oxidase, subunit
M1S17_08200	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1S17_08210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1S17_08215	COG4774	siderophore transport
M1S17_08230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1S17_08235	COG0569	domain protein
M1S17_08240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1S17_08270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M1S17_08275	COG0542	response to heat
M1S17_08300	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S17_08300	COG1902	pentaerythritol trinitrate reductase activity
M1S17_08345	COG2323	membrane
M1S17_08350	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M1S17_08360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S17_08365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S17_08370	COG0183	Belongs to the thiolase family
M1S17_08375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1S17_08380	COG0596	Alpha beta hydrolase
M1S17_08385	COG2271	Major facilitator Superfamily
M1S17_08390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1S17_08395	COG3485	protocatechuate 3,4-dioxygenase
M1S17_08400	COG3485	protocatechuate 3,4-dioxygenase
M1S17_08405	COG0710	3-dehydroquinate dehydratase activity
M1S17_08410	COG3420	alginic acid biosynthetic process
M1S17_08415	COG3659	wide pore channel activity
M1S17_08420	COG4993	Dehydrogenase
M1S17_08430	COG2391	methyltransferase activity
M1S17_08445	COG1414	Transcriptional regulator
M1S17_08450	COG0583	DNA-binding transcription factor activity
M1S17_08455	COG1960	acyl-CoA dehydrogenase activity
M1S17_08480	COG2814	Major facilitator Superfamily
M1S17_08490	COG0154	amidase activity
M1S17_08510	COG4638	Rieske (2fe-2S)
M1S17_08520	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_08530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S17_08540	COG3733	amine oxidase
M1S17_08550	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_08560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S17_08565	COG0183	Belongs to the thiolase family
M1S17_08570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S17_08575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S17_08585	COG4829	muconolactone delta-isomerase
M1S17_08590	COG4948	Mandelate Racemase Muconate Lactonizing
M1S17_08595	COG0583	DNA-binding transcription factor activity
M1S17_08605	COG2186	Transcriptional regulator
M1S17_08645	COG1960	acyl-CoA dehydrogenase activity
M1S17_08650	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_08655	COG3829	transcription factor binding
M1S17_08665	COG3162	membrane
M1S17_08680	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_08695	COG0753	catalase activity
M1S17_08715	COG1846	Transcriptional regulator
M1S17_08720	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S17_08720	COG1902	pentaerythritol trinitrate reductase activity
M1S17_08730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1S17_08760	COG1309	transcriptional regulator
M1S17_08770	COG1335	isochorismatase
M1S17_08775	COG0583	DNA-binding transcription factor activity
M1S17_08785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S17_08785	COG0475	glutathione-regulated potassium exporter activity
M1S17_08795	COG1473	amidohydrolase
M1S17_08805	COG2831	hemolysin activation secretion protein
M1S17_08810	COG3210	domain, Protein
M1S17_08840	COG2188	Transcriptional regulator
M1S17_08855	COG0583	DNA-binding transcription factor activity
M1S17_08885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1S17_08915	COG1566	PFAM secretion protein HlyD family protein
M1S17_08930	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_08935	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_08940	COG0129	dihydroxy-acid dehydratase activity
M1S17_08950	COG0583	DNA-binding transcription factor activity
M1S17_08955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1S17_08965	COG2084	Dehydrogenase
M1S17_08970	COG2207	Transcriptional regulator
M1S17_08985	COG1064	alcohol dehydrogenase
M1S17_08995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1S17_09000	COG1120	ATPase activity
M1S17_09020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1S17_09140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
M1S17_09190	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_09205	COG2207	Transcriptional regulator
M1S17_09245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S17_09250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1S17_09255	COG1538	Outer membrane efflux protein
M1S17_09265	COG2072	flavoprotein involved in K transport
M1S17_09285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S17_09305	COG3539	Fimbrial protein
M1S17_09335	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
M1S17_09345	COG0753	catalase activity
M1S17_09360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1S17_09420	COG3433	isochorismatase activity
M1S17_09420	COG1535	isochorismatase
M1S17_09425	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_09430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
M1S17_09435	COG4149	molybdate abc transporter
M1S17_09440	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1S17_09450	COG4638	Rieske (2fe-2S)
M1S17_09455	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1S17_09460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S17_09460	COG0543	2 iron, 2 sulfur cluster binding
M1S17_09485	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_09500	COG2207	Transcriptional regulator
M1S17_09510	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_09515	COG2610	gluconate transmembrane transporter activity
M1S17_09530	COG0583	DNA-binding transcription factor activity
M1S17_09540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S17_09545	COG2031	fatty acid transporter
M1S17_09550	COG0183	Belongs to the thiolase family
M1S17_09555	COG0583	DNA-binding transcription factor activity
M1S17_09560	COG0583	DNA-binding transcription factor activity
M1S17_09575	COG1027	Aspartate ammonia-lyase
M1S17_09585	COG0477	Major facilitator Superfamily
M1S17_09605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S17_09610	COG4521	taurine ABC transporter
M1S17_09625	COG2188	Transcriptional regulator
M1S17_09635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1S17_09640	COG1733	regulation of RNA biosynthetic process
M1S17_09645	COG2207	Transcriptional regulator
M1S17_09645	COG3708	Transcriptional regulator
M1S17_09660	COG0730	response to heat
M1S17_09675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S17_09675	COG3453	Protein conserved in bacteria
M1S17_09685	COG3781	membrane
M1S17_09690	COG1063	alcohol dehydrogenase
M1S17_09700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S17_09705	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1S17_09710	COG0022	dehydrogenase e1 component
M1S17_09715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1S17_09720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1S17_09735	COG3706	GGDEF domain
M1S17_09750	COG0133	tryptophan synthase activity
M1S17_09760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1S17_09795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M1S17_09820	COG2226	methyltransferase
M1S17_09875	COG0842	Transport permease protein
M1S17_09880	COG0842	Transport permease protein
M1S17_09885	COG1131	(ABC) transporter
M1S17_09900	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S17_09905	COG4773	Receptor
M1S17_09925	COG0730	response to heat
M1S17_09930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M1S17_09950	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
M1S17_09965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1S17_10005	COG4264	IucA IucC family
M1S17_10010	COG4264	IucA IucC family
M1S17_10030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1S17_10045	COG1960	acyl-CoA dehydrogenase activity
M1S17_10050	COG1960	acyl-CoA dehydrogenase activity
M1S17_10055	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1S17_10060	COG2207	Transcriptional regulator
M1S17_10065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1S17_10070	COG0776	regulation of translation
M1S17_10095	COG0822	iron-sulfur transferase activity
M1S17_10100	COG0316	Belongs to the HesB IscA family
M1S17_10130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1S17_10150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1S17_10155	COG0702	epimerase
M1S17_10190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1S17_10200	COG0339	signal peptide processing
M1S17_10260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M1S17_10265	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M1S17_10295	COG0776	regulation of translation
M1S17_10360	COG0084	hydrolase, TatD family'
M1S17_10380	COG1663	tetraacyldisaccharide 4'-kinase activity
M1S17_10385	COG1132	(ABC) transporter
M1S17_10395	COG0811	peptide transport
M1S17_10400	COG1475	DNA binding
M1S17_10405	COG1192	Involved in chromosome partitioning
M1S17_10415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1S17_10430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1S17_10435	COG0191	fructose-bisphosphate aldolase activity
M1S17_10455	COG0424	maF-like protein
M1S17_10460	COG2850	peptidyl-arginine hydroxylation
M1S17_10470	COG0640	Transcriptional regulator
M1S17_10480	COG3619	membrane
M1S17_10485	COG3122	Protein conserved in bacteria
M1S17_10490	COG1132	(ABC) transporter
M1S17_10510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1S17_10515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1S17_10525	COG0506	proline dehydrogenase activity
M1S17_10525	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M1S17_10525	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M1S17_10530	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1S17_10545	COG3698	Phosphodiester glycosidase
M1S17_10555	COG2353	YceI-like domain
M1S17_10565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M1S17_10615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M1S17_10615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M1S17_10640	COG3539	Fimbrial protein
M1S17_10645	COG3121	Chaperone
M1S17_10670	COG0697	spore germination
M1S17_10680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1S17_10690	COG0583	DNA-binding transcription factor activity
M1S17_10710	COG1309	transcriptional regulator
M1S17_10725	COG1522	sequence-specific DNA binding
M1S17_10735	COG1126	abc transporter atp-binding protein
M1S17_10740	COG0765	amino acid transport
M1S17_10745	COG0765	amino acid transport
M1S17_10775	COG1464	Belongs to the NlpA lipoprotein family
M1S17_10785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1S17_10790	COG2011	ABC-type metal ion transport system permease component
M1S17_10795	COG0012	GTP binding
M1S17_10820	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1S17_10860	COG0386	Belongs to the glutathione peroxidase family
M1S17_10870	COG0436	Aminotransferase
M1S17_10915	COG3634	alkyl hydroperoxide reductase activity
M1S17_10935	COG0583	DNA-binding transcription factor activity
M1S17_10940	COG0798	PFAM Bile acid sodium symporter
M1S17_10945	COG0640	Transcriptional regulator
M1S17_10960	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1S17_10970	COG0583	DNA-binding transcription factor activity
M1S17_10980	COG1953	Uracil, thiamine, allantoin
M1S17_10990	COG2175	clavaminate synthase activity
M1S17_10995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S17_11000	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
M1S17_11005	COG4521	taurine ABC transporter
M1S17_11015	COG0477	Major facilitator Superfamily
M1S17_11035	COG1271	oxidase subunit
M1S17_11040	COG1294	oxidase, subunit
M1S17_11050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S17_11070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1S17_11090	COG3052	prosthetic group binding
M1S17_11095	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
M1S17_11105	COG2814	Major facilitator Superfamily
M1S17_11125	COG1346	cytolysis
M1S17_11135	COG0583	DNA-binding transcription factor activity
M1S17_11140	COG0625	glutathione transferase activity
M1S17_11145	COG0625	glutathione transferase activity
M1S17_11150	COG0583	DNA-binding transcription factor activity
M1S17_11165	COG1045	serine acetyltransferase
M1S17_11170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1S17_11175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1S17_11185	COG1280	lysine exporter protein (LysE YggA)
M1S17_11200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S17_11205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S17_11210	COG1126	abc transporter atp-binding protein
M1S17_11215	COG0765	amino acid transport
M1S17_11220	COG0765	amino acid transport
M1S17_11240	COG0784	Response regulator, receiver
M1S17_11240	COG2205	protein histidine kinase activity
M1S17_11260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M1S17_11280	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_11330	COG0583	DNA-binding transcription factor activity
M1S17_11350	COG0318	PFAM AMP-dependent synthetase and ligase
M1S17_11355	COG1309	transcriptional regulator
M1S17_11360	COG1960	acyl-CoA dehydrogenase activity
M1S17_11365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1S17_11370	COG1024	Enoyl-CoA hydratase
M1S17_11385	COG0583	DNA-binding transcription factor activity
M1S17_11400	COG1960	acyl-CoA dehydrogenase activity
M1S17_11410	COG2814	Major facilitator Superfamily
M1S17_11420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S17_11425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S17_11430	COG2814	Major facilitator Superfamily
M1S17_11435	COG1960	acyl-CoA dehydrogenase activity
M1S17_11440	COG1024	Enoyl-CoA hydratase
M1S17_11445	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_11450	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S17_11455	COG0183	Belongs to the thiolase family
M1S17_11465	COG2814	Major facilitator Superfamily
M1S17_11475	COG1024	Enoyl-CoA hydratase
M1S17_11490	COG1960	acyl-CoA dehydrogenase activity
M1S17_11495	COG2814	Major facilitator Superfamily
M1S17_11500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1S17_11505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1S17_11520	COG3842	ATPase activity
M1S17_11525	COG1840	ABC-type Fe3 transport system, periplasmic component
M1S17_11535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S17_11540	COG1414	Transcriptional regulator
M1S17_11550	COG0583	DNA-binding transcription factor activity
M1S17_11555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1S17_11560	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_11570	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1S17_11580	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_11585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S17_11590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S17_11595	COG2267	carboxylic ester hydrolase activity
M1S17_11615	COG3038	cytochrome b561
M1S17_11620	COG0753	catalase activity
M1S17_11655	COG2050	protein possibly involved in aromatic compounds catabolism
M1S17_11665	COG3327	negative regulation of DNA-templated transcription, initiation
M1S17_11670	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
M1S17_11675	COG0183	Belongs to the thiolase family
M1S17_11680	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S17_11685	COG1024	Enoyl-CoA hydratase
M1S17_11690	COG1024	Enoyl-CoA hydratase
M1S17_11695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S17_11700	COG2151	metal-sulfur cluster biosynthetic enzyme
M1S17_11705	COG3396	Phenylacetate-CoA oxygenase
M1S17_11710	COG3460	Phenylacetate-CoA oxygenase
M1S17_11715	COG3396	Phenylacetate-CoA oxygenase
M1S17_11720	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_11720	COG2030	dehydratase
M1S17_11725	COG1760	l-serine dehydratase
M1S17_11730	COG0531	amino acid
M1S17_11735	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_11750	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S17_11760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S17_11780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S17_11790	COG0789	Transcriptional regulator
M1S17_11805	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1S17_11820	COG2807	transmembrane transport
M1S17_11825	COG0590	tRNA wobble adenosine to inosine editing
M1S17_11945	COG1116	anion transmembrane transporter activity
M1S17_11950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S17_11960	COG0864	Transcriptional regulator
M1S17_11980	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S17_11985	COG0439	Biotin carboxylase
M1S17_12000	COG1063	alcohol dehydrogenase
M1S17_12010	COG1309	transcriptional regulator
M1S17_12030	COG0038	chloride channel
M1S17_12035	COG4770	biotin carboxylase activity
M1S17_12055	COG1914	H( )-stimulated, divalent metal cation uptake system
M1S17_12060	COG0583	DNA-binding transcription factor activity
M1S17_12110	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S17_12130	COG2814	Major facilitator Superfamily
M1S17_12145	COG1560	Kdo2-lipid A biosynthetic process
M1S17_12155	COG5006	permease, DMT superfamily
M1S17_12160	COG1522	sequence-specific DNA binding
M1S17_12175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
M1S17_12185	COG4122	O-methyltransferase activity
M1S17_12215	COG1538	Outer membrane efflux protein
M1S17_12220	COG1137	ATPase activity
M1S17_12225	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M1S17_12235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M1S17_12240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M1S17_12240	COG0517	IMP dehydrogenase activity
M1S17_12275	COG2814	Major facilitator Superfamily
M1S17_12310	COG1278	Cold shock
M1S17_12315	COG1280	lysine exporter protein (LysE YggA)
M1S17_12345	COG1570	exodeoxyribonuclease VII activity
M1S17_12395	COG0583	DNA-binding transcription factor activity
M1S17_12405	COG4638	Rieske (2fe-2S)
M1S17_12410	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1S17_12415	COG0543	2 iron, 2 sulfur cluster binding
M1S17_12415	COG0633	Ferredoxin
M1S17_12420	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_12425	COG3135	benzoate transporter
M1S17_12430	COG2814	Major facilitator Superfamily
M1S17_12445	COG1643	Atp-dependent helicase
M1S17_12450	COG0450	alkyl hydroperoxide reductase
M1S17_12460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
M1S17_12470	COG3634	alkyl hydroperoxide reductase activity
M1S17_12490	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M1S17_12495	COG0625	glutathione transferase activity
M1S17_12505	COG2885	chlorophyll binding
M1S17_12540	COG0542	response to heat
M1S17_12555	COG1765	OsmC-like protein
M1S17_12575	COG0667	Aldo Keto reductase
M1S17_12590	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M1S17_12600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1S17_12610	COG0527	aspartate kinase activity
M1S17_12620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M1S17_12655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1S17_12705	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_12725	COG0531	amino acid
M1S17_12735	COG1113	amino acid transport
M1S17_12775	COG3209	COG3209 Rhs family protein
M1S17_12805	COG4269	membrane
M1S17_12820	COG1902	pentaerythritol trinitrate reductase activity
M1S17_12820	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S17_12830	COG2203	Gaf domain
M1S17_12830	COG3706	GGDEF domain
M1S17_12830	COG4251	negative regulation of phosphorylation
M1S17_12830	COG5001	Diguanylate cyclase
M1S17_12840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S17_12860	COG4172	Belongs to the ABC transporter superfamily
M1S17_12865	COG4239	(ABC) transporter, permease
M1S17_12870	COG4174	ABC transporter (Permease)
M1S17_12880	COG0741	lytic transglycosylase activity
M1S17_12880	COG1388	LysM domain
M1S17_12880	COG0741	lytic transglycosylase activity
M1S17_12880	COG1388	LysM domain
M1S17_12885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S17_12925	COG0583	DNA-binding transcription factor activity
M1S17_12930	COG1279	arginine transmembrane transporter activity
M1S17_12950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S17_12955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S17_12960	COG0006	proline dipeptidase activity
M1S17_13045	COG1196	nuclear chromosome segregation
M1S17_13045	COG0741	lytic transglycosylase activity
M1S17_13045	COG0739	heme binding
M1S17_13105	COG4695	Portal protein
M1S17_13205	COG0305	Participates in initiation and elongation during chromosome replication
M1S17_13220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M1S17_13275	COG2194	sulfuric ester hydrolase activity
M1S17_13645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1S17_13670	COG3384	dioxygenase
M1S17_13680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1S17_13685	COG2878	Part of a membrane complex involved in electron transport
M1S17_13690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1S17_13715	COG0768	penicillin binding
M1S17_13720	COG0742	ribosomal rna small subunit methyltransferase
M1S17_13735	COG0830	nickel cation binding
M1S17_13745	COG0804	urea catabolic process
M1S17_13785	COG1253	flavin adenine dinucleotide binding
M1S17_13790	COG2851	Citrate transporter
M1S17_13840	COG1773	rubredoxin
M1S17_13845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S17_13855	COG0583	DNA-binding transcription factor activity
M1S17_13880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M1S17_13885	COG4181	ATPase activity
M1S17_13930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
M1S17_13950	COG0306	phosphate transporter
M1S17_13960	COG3958	Transketolase
M1S17_13965	COG3959	Transketolase, thiamine diphosphate binding domain
M1S17_13970	COG2271	Major facilitator Superfamily
M1S17_13975	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_13980	COG0583	DNA-binding transcription factor activity
M1S17_13995	COG2223	nitrite transmembrane transporter activity
M1S17_14000	COG2207	Transcriptional regulator
M1S17_14005	COG2066	Belongs to the glutaminase family
M1S17_14010	COG0242	peptide deformylase activity
M1S17_14015	COG0477	Major facilitator Superfamily
M1S17_14025	COG0028	Belongs to the TPP enzyme family
M1S17_14040	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_14045	COG2267	carboxylic ester hydrolase activity
M1S17_14055	COG2271	Major facilitator Superfamily
M1S17_14060	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S17_14070	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_14090	COG1414	Transcriptional regulator
M1S17_14105	COG1024	Enoyl-CoA hydratase
M1S17_14115	COG1215	transferase activity, transferring glycosyl groups
M1S17_14120	COG0726	polysaccharide deacetylase
M1S17_14120	COG1649	PFAM Uncharacterised BCR, COG1649
M1S17_14130	COG4681	YaeQ
M1S17_14140	COG0523	cobalamin synthesis protein
M1S17_14150	COG1607	acyl-coa hydrolase
M1S17_14160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S17_14165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S17_14170	COG1309	transcriptional regulator
M1S17_14195	COG2040	homocysteine
M1S17_14200	COG0531	amino acid
M1S17_14225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S17_14230	COG0477	Major facilitator Superfamily
M1S17_14300	COG1061	Type III restriction enzyme res subunit
M1S17_14310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1S17_14315	COG1192	Involved in chromosome partitioning
M1S17_14325	COG1061	Type III restriction enzyme res subunit
M1S17_14420	COG0592	DNA-directed DNA polymerase activity
M1S17_14460	COG2026	Addiction module toxin, RelE StbE family
M1S17_14605	COG3755	Protein conserved in bacteria
M1S17_14650	COG1484	DNA-dependent DNA replication
M1S17_14740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S17_14810	COG0405	Gamma-glutamyltransferase
M1S17_14815	COG2814	Major facilitator Superfamily
M1S17_14825	COG2050	protein possibly involved in aromatic compounds catabolism
M1S17_14840	COG1090	epimerase
M1S17_14860	COG0420	3'-5' exonuclease activity
M1S17_14885	COG0735	belongs to the Fur family
M1S17_14890	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M1S17_14910	COG0121	glutamine amidotransferase
M1S17_14925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S17_14935	COG0210	DNA helicase
M1S17_14940	COG2885	chlorophyll binding
M1S17_14945	COG0204	Acyl-transferase
M1S17_14960	COG2894	cell division
M1S17_14980	COG1280	lysine exporter protein (LysE YggA)
M1S17_14985	COG1674	ftsk spoiiie
M1S17_14985	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M1S17_14990	COG0492	ferredoxin-NADP+ reductase activity
M1S17_14995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
M1S17_15005	COG0456	acetyltransferase
M1S17_15050	COG1981	membrane
M1S17_15065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M1S17_15065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1S17_15085	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_15095	COG0657	acetylesterase activity
M1S17_15105	COG0473	3-isopropylmalate dehydrogenase activity
M1S17_15110	COG0583	DNA-binding transcription factor activity
M1S17_15130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1S17_15155	COG0564	pseudouridine synthase activity
M1S17_15165	COG0358	DNA primase activity
M1S17_15180	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
M1S17_15210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1S17_15240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M1S17_15250	COG0352	thiamine-phosphate diphosphorylase activity
M1S17_15250	COG0351	phosphomethylpyrimidine kinase
M1S17_15250	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1S17_15255	COG1652	LysM domain
M1S17_15280	COG1399	metal-binding, possibly nucleic acid-binding protein
M1S17_15285	COG3101	peptidyl-lysine hydroxylation
M1S17_15290	COG0009	L-threonylcarbamoyladenylate synthase
M1S17_15295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M1S17_15300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M1S17_15315	COG4106	trans-aconitate 2-methyltransferase activity
M1S17_15330	COG0596	Alpha beta hydrolase
M1S17_15330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S17_15330	COG2226	methyltransferase
M1S17_15335	COG1877	trehalose-phosphatase activity
M1S17_15340	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
M1S17_15345	COG2223	nitrite transmembrane transporter activity
M1S17_15365	COG1196	nuclear chromosome segregation
M1S17_15375	COG0730	response to heat
M1S17_15390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1S17_15400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1S17_15450	COG0489	protein tyrosine kinase activity
M1S17_15460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S17_15460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S17_15490	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M1S17_15495	COG2081	HI0933 family
M1S17_15505	COG0668	transmembrane transport
M1S17_15525	COG0583	DNA-binding transcription factor activity
M1S17_15545	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1S17_15550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1S17_15580	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M1S17_15620	COG0745	RESPONSE REGULATOR receiver
M1S17_15640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1S17_15650	COG2205	protein histidine kinase activity
M1S17_15720	COG4993	Dehydrogenase
M1S17_15745	COG0384	phenazine biosynthesis protein PhzF
M1S17_15770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S17_15785	COG0583	DNA-binding transcription factor activity
M1S17_15815	COG0583	DNA-binding transcription factor activity
M1S17_15830	COG0583	DNA-binding transcription factor activity
M1S17_15845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M1S17_15850	COG2814	Major facilitator Superfamily
M1S17_15855	COG1960	acyl-CoA dehydrogenase activity
M1S17_15860	COG0583	DNA-binding transcription factor activity
M1S17_15865	COG1063	alcohol dehydrogenase
M1S17_15895	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M1S17_15900	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1S17_15905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1S17_15920	COG3667	copper resistance
M1S17_15925	COG2132	Multicopper oxidase
M1S17_15935	COG0561	phosphatase activity
M1S17_15940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1S17_15965	COG1214	PFAM Peptidase M22, glycoprotease
M1S17_16015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1S17_16025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1S17_16030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M1S17_16035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M1S17_16095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1S17_16105	COG1846	Transcriptional regulator
M1S17_16110	COG1764	response to oxidative stress
M1S17_16150	COG0037	tRNA processing
M1S17_16160	COG0248	Ppx GppA phosphatase
M1S17_16190	COG0072	phenylalanine-tRNA ligase activity
M1S17_16235	COG1238	metal cluster binding
M1S17_16240	COG0625	glutathione transferase activity
M1S17_16255	COG0318	PFAM AMP-dependent synthetase and ligase
M1S17_16260	COG3028	Belongs to the UPF0307 family
M1S17_16265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1S17_16285	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1S17_16290	COG0617	tRNA 3'-terminal CCA addition
M1S17_16295	COG1555	photosystem II stabilization
M1S17_16300	COG3956	TIGRFAM MazG family protein
M1S17_16310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1S17_16330	COG0784	Response regulator, receiver
M1S17_16330	COG2205	protein histidine kinase activity
M1S17_16330	COG5002	protein histidine kinase activity
M1S17_16335	COG1024	Enoyl-CoA hydratase
M1S17_16340	COG2084	Dehydrogenase
M1S17_16345	COG3622	Belongs to the hyi family
M1S17_16375	COG0697	spore germination
M1S17_16385	COG2814	Major facilitator Superfamily
M1S17_16390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1S17_16400	COG0583	DNA-binding transcription factor activity
M1S17_16410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1S17_16425	COG0084	hydrolase, TatD family'
M1S17_16440	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M1S17_16470	COG0440	acetolactate synthase activity
M1S17_16475	COG0028	Belongs to the TPP enzyme family
M1S17_16500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S17_16505	COG1136	(ABC) transporter
M1S17_16505	COG0577	efflux transmembrane transporter activity
M1S17_16525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M1S17_16530	COG1162	GTPase activity
M1S17_16540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M1S17_16560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1S17_16565	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_16605	COG2986	histidine ammonia-lyase
M1S17_16620	COG0318	PFAM AMP-dependent synthetase and ligase
M1S17_16630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1S17_16675	COG1426	Protein conserved in bacteria
M1S17_16710	COG0793	Belongs to the peptidase S41A family
M1S17_16725	COG2267	carboxylic ester hydrolase activity
M1S17_16735	COG1012	belongs to the aldehyde dehydrogenase family
M1S17_16740	COG3265	gluconokinase activity
M1S17_16750	COG0800	Aldolase
M1S17_16760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M1S17_16765	COG0280	phosphate acetyltransferase
M1S17_16765	COG0857	belongs to the CobB CobQ family
M1S17_16770	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M1S17_16770	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M1S17_16790	COG0740	serine-type endopeptidase activity
M1S17_16800	COG4774	siderophore transport
M1S17_16810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1S17_16820	COG2813	Specifically methylates the guanine in position
M1S17_16820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S17_16920	COG0788	formyltetrahydrofolate deformylase activity
M1S17_16945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S17_16945	COG4651	solute:proton antiporter activity
M1S17_16965	COG0724	RNA recognition motif
M1S17_16970	COG0210	DNA helicase
M1S17_16995	COG1733	regulation of RNA biosynthetic process
M1S17_17005	COG2900	Belongs to the SlyX family
M1S17_17010	COG0488	(ABC) transporter
M1S17_17015	COG1280	lysine exporter protein (LysE YggA)
M1S17_17020	COG1560	Kdo2-lipid A biosynthetic process
M1S17_17030	COG1301	dicarboxylic acid transport
M1S17_17085	COG0473	3-isopropylmalate dehydrogenase activity
M1S17_17150	COG0583	DNA-binding transcription factor activity
M1S17_17160	COG0625	glutathione transferase activity
M1S17_17165	COG2378	regulation of single-species biofilm formation
M1S17_17170	COG0546	phosphoglycolate phosphatase activity
M1S17_17180	COG1530	ribonuclease E activity
M1S17_17185	COG0318	PFAM AMP-dependent synthetase and ligase
M1S17_17200	COG0583	DNA-binding transcription factor activity
M1S17_17205	COG4221	oxidoreductase activity
M1S17_17210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1S17_17220	COG0534	Mate efflux family protein
M1S17_17235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
M1S17_17275	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
M1S17_17280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S17_17295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1S17_17305	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
M1S17_17305	COG0644	oxidoreductase
M1S17_17310	COG0425	Belongs to the sulfur carrier protein TusA family
M1S17_17315	COG4535	Mg2 and Co2 transporter CorC
M1S17_17325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S17_17345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1S17_17350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S17_17350	COG0475	glutathione-regulated potassium exporter activity
M1S17_17355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M1S17_17365	COG0484	heat shock protein binding
M1S17_17370	COG0789	Transcriptional regulator
M1S17_17375	COG0598	Magnesium transport protein CorA
M1S17_17390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1S17_17395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1S17_17400	COG1074	ATP-dependent DNA helicase activity
M1S17_17405	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M1S17_17425	COG2226	methyltransferase
M1S17_17445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M1S17_17460	COG2111	Na H antiporter
M1S17_17460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1S17_17465	COG1006	Multisubunit Na H antiporter MnhC subunit
M1S17_17470	COG0651	ATP synthesis coupled electron transport
M1S17_17475	COG1863	multisubunit Na H antiporter MnhE subunit
M1S17_17480	COG2212	antiporter activity
M1S17_17485	COG1320	monovalent cation:proton antiporter activity
M1S17_17500	COG0195	Participates in both transcription termination and antitermination
M1S17_17550	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1S17_17555	COG0237	dephospho-CoA kinase activity
M1S17_17565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1S17_17580	COG0497	DNA recombination
M1S17_17590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M1S17_17620	COG2169	Transcriptional regulator
M1S17_17620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1S17_17625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1S17_17700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1S17_17715	COG0326	Molecular chaperone. Has ATPase activity
M1S17_17730	COG2056	Na+-H+ antiporter family
M1S17_17735	COG0596	Alpha beta hydrolase
M1S17_17830	COG0546	phosphoglycolate phosphatase activity
M1S17_17835	COG1716	ATPase activity
M1S17_17880	COG0181	hydroxymethylbilane synthase activity
M1S17_17890	COG3275	phosphorelay sensor kinase activity
M1S17_17910	COG1538	Outer membrane efflux protein
M1S17_17915	COG0697	spore germination
M1S17_17940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1S17_17945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1S17_17950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1S17_17955	COG0772	Belongs to the SEDS family
M1S17_17980	COG4974	Belongs to the 'phage' integrase family
M1S17_17985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S17_17995	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M1S17_18005	COG2197	response regulator
M1S17_18020	COG0793	Belongs to the peptidase S41A family
M1S17_18025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M1S17_18030	COG0795	lipopolysaccharide-transporting ATPase activity
M1S17_18070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1S17_18070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1S17_18080	COG0004	ammonium transporteR
M1S17_18085	COG0347	Belongs to the P(II) protein family
M1S17_18145	COG0659	secondary active sulfate transmembrane transporter activity
M1S17_18150	COG0589	response to stress
M1S17_18190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S17_18235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1S17_18265	COG0659	secondary active sulfate transmembrane transporter activity
M1S17_18270	COG0589	response to stress
M1S17_18305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S17_18315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S17_18335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M1S17_18350	COG0318	PFAM AMP-dependent synthetase and ligase
M1S17_18360	COG0477	Major facilitator Superfamily
M1S17_18365	COG2860	membrane
M1S17_18375	COG1253	flavin adenine dinucleotide binding
M1S17_18395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1S17_18435	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1S17_18445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1S17_18515	COG0758	DNA mediated transformation
M1S17_18525	COG0697	spore germination
M1S17_18530	COG1309	transcriptional regulator
M1S17_18545	COG0386	Belongs to the glutathione peroxidase family
M1S17_18610	COG1121	(ABC) transporter
M1S17_18615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1S17_18620	COG1280	lysine exporter protein (LysE YggA)
M1S17_18625	COG2837	iron assimilation
M1S17_18635	COG0281	malic enzyme
M1S17_18680	COG0519	Catalyzes the synthesis of GMP from XMP
M1S17_18680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1S17_18685	COG4399	Belongs to the UPF0754 family
M1S17_18690	COG2259	Doxx family
M1S17_18695	COG0586	Pfam SNARE associated Golgi protein
M1S17_18710	COG1192	Involved in chromosome partitioning
M1S17_18720	COG0271	Belongs to the BolA IbaG family
M1S17_18740	COG2267	carboxylic ester hydrolase activity
M1S17_18760	COG3321	synthase
M1S17_18760	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M1S17_18760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M1S17_18760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1S17_18765	COG1960	acyl-CoA dehydrogenase activity
M1S17_18775	COG2197	response regulator
M1S17_18785	COG3916	Acyl-homoserine-lactone synthase
M1S17_18790	COG0477	Major facilitator Superfamily
M1S17_18795	COG1024	Enoyl-CoA hydratase
M1S17_18800	COG1024	Enoyl-CoA hydratase
M1S17_18805	COG1960	acyl-CoA dehydrogenase activity
M1S17_18810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S17_18830	COG1113	amino acid transport
M1S17_18835	COG1113	amino acid transport
M1S17_18840	COG0251	oxidation-reduction process
M1S17_18880	COG0564	pseudouridine synthase activity
M1S17_18940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1S17_18955	COG1802	Transcriptional regulator
M1S17_18965	COG1448	Aminotransferase
M1S17_18970	COG0277	FAD linked oxidase domain protein
M1S17_18980	COG2186	Transcriptional regulator
M1S17_18990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S17_18995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1S17_19010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1S17_19015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1S17_19020	COG1216	Glycosyl transferase, family 2
M1S17_19050	COG2089	acid synthase
M1S17_19065	COG1083	cytidylyl-transferase
M1S17_19070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M1S17_19075	COG1086	Polysaccharide biosynthesis protein
M1S17_19080	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M1S17_19085	COG1596	polysaccharide export
M1S17_19110	COG0728	peptidoglycan biosynthetic process
M1S17_19115	COG3023	N-Acetylmuramoyl-L-alanine amidase
M1S17_19175	COG0546	phosphoglycolate phosphatase activity
M1S17_19180	COG1028	Short-chain dehydrogenase reductase Sdr
M1S17_19200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S17_19205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S17_19210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S17_19215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S17_19220	COG1116	anion transmembrane transporter activity
M1S17_19225	COG1309	transcriptional regulator
M1S17_19230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M1S17_19240	COG0196	riboflavin kinase activity
M1S17_19245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1S17_19255	COG1047	Peptidyl-prolyl cis-trans
M1S17_19295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1S17_19300	COG0657	acetylesterase activity
M1S17_19320	COG0583	DNA-binding transcription factor activity
M1S17_19350	COG2951	lytic endotransglycosylase activity
M1S17_19355	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1S17_19370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M1S17_19380	COG0671	phosphoesterase, PA-phosphatase related
M1S17_19385	COG0861	Integral membrane protein TerC family
M1S17_19395	COG0754	glutathionylspermidine amidase activity
M1S17_19405	COG0402	S-adenosylhomocysteine deaminase activity
M1S17_19420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S17_19425	COG1230	cation diffusion facilitator family transporter
M1S17_19440	COG0706	membrane insertase activity
M1S17_19480	COG0358	DNA primase activity
M1S17_19535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1S17_19580	COG0587	DNA-directed DNA polymerase activity
M1S17_19595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1S17_19595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1S17_19650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M1S17_19650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1S17_19655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1S17_19695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S17_19740	COG1309	transcriptional regulator
M1S17_19750	COG1902	pentaerythritol trinitrate reductase activity
M1S17_19760	COG1979	alcohol dehydrogenase
M1S17_19775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
M1S17_19800	COG1063	alcohol dehydrogenase
M1S17_19880	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1S17_19900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system