locus-tag	class	description
M1S53_00010	COG0592	DNA-directed DNA polymerase activity
M1S53_00020	COG0187	DNA topoisomerase II activity
M1S53_00030	COG0586	Pfam SNARE associated Golgi protein
M1S53_00035	COG0488	(ABC) transporter
M1S53_00060	COG0596	Alpha beta hydrolase
M1S53_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
M1S53_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M1S53_00110	COG0733	neurotransmitter:sodium symporter activity
M1S53_00150	COG2233	PERMEase
M1S53_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S53_00200	COG2814	Major facilitator Superfamily
M1S53_00205	COG0656	L-ascorbic acid biosynthetic process
M1S53_00210	COG0583	DNA-binding transcription factor activity
M1S53_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S53_00230	COG1064	alcohol dehydrogenase
M1S53_00235	COG2818	Glycosylase
M1S53_00250	COG1194	a g-specific adenine glycosylase
M1S53_00270	COG2983	Belongs to the UPF0260 family
M1S53_00275	COG2133	pyrroloquinoline quinone binding
M1S53_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1S53_00285	COG2116	formate transmembrane transporter activity
M1S53_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S53_00310	COG1335	isochorismatase
M1S53_00315	COG0385	Bile acid
M1S53_00320	COG0534	Mate efflux family protein
M1S53_00325	COG1683	Conserved Protein
M1S53_00345	COG0625	glutathione transferase activity
M1S53_00355	COG1113	amino acid transport
M1S53_00365	COG0523	cobalamin synthesis protein
M1S53_00375	COG2188	Transcriptional regulator
M1S53_00405	COG0010	Belongs to the arginase family
M1S53_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1S53_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M1S53_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1S53_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M1S53_00540	COG0534	Mate efflux family protein
M1S53_00545	COG0436	Aminotransferase
M1S53_00550	COG2733	membrane
M1S53_00565	COG2918	glutathione biosynthetic process
M1S53_00580	COG1388	LysM domain
M1S53_00580	COG0791	NLP P60 protein
M1S53_00595	COG3150	esterase
M1S53_00605	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
M1S53_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S53_00630	COG2233	PERMEase
M1S53_00635	COG2351	hydroxyisourate hydrolase activity
M1S53_00670	COG3706	GGDEF domain
M1S53_00685	COG1393	Belongs to the ArsC family
M1S53_00690	COG0708	Exodeoxyribonuclease III
M1S53_00710	COG0189	ligase activity
M1S53_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1S53_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1S53_00755	COG4942	peptidase
M1S53_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1S53_00775	COG2119	membrane
M1S53_00780	COG4774	siderophore transport
M1S53_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S53_00785	COG0426	domain, Protein
M1S53_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1S53_00830	COG1902	pentaerythritol trinitrate reductase activity
M1S53_00835	COG1519	Transferase
M1S53_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1S53_00845	COG0668	transmembrane transport
M1S53_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S53_00860	COG1335	isochorismatase
M1S53_00865	COG1522	sequence-specific DNA binding
M1S53_00870	COG3328	transposase activity
M1S53_00895	COG0784	Response regulator, receiver
M1S53_00895	COG2198	Histidine kinase
M1S53_00895	COG2205	protein histidine kinase activity
M1S53_00900	COG3162	membrane
M1S53_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1S53_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S53_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1S53_00940	COG1309	transcriptional regulator
M1S53_00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1S53_00965	COG0352	thiamine-phosphate diphosphorylase activity
M1S53_00965	COG0351	phosphomethylpyrimidine kinase
M1S53_00975	COG2814	Major facilitator Superfamily
M1S53_00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1S53_01000	COG1113	amino acid transport
M1S53_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1S53_01015	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_01025	COG1335	isochorismatase
M1S53_01055	COG2814	Major facilitator Superfamily
M1S53_01060	COG0583	DNA-binding transcription factor activity
M1S53_01080	COG0667	Aldo Keto reductase
M1S53_01115	COG1733	regulation of RNA biosynthetic process
M1S53_01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S53_01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1S53_01200	COG2329	Antibiotic biosynthesis monooxygenase
M1S53_01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M1S53_01260	COG0427	acetyl-CoA hydrolase
M1S53_01285	COG0659	secondary active sulfate transmembrane transporter activity
M1S53_01290	COG4221	oxidoreductase activity
M1S53_01295	COG2873	o-acetylhomoserine
M1S53_01300	COG0488	(ABC) transporter
M1S53_01385	COG0833	amino acid
M1S53_01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1S53_01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1S53_01450	COG2226	methyltransferase
M1S53_01500	COG0067	glutamate synthase
M1S53_01500	COG0069	glutamate synthase activity
M1S53_01500	COG0070	glutamate synthase
M1S53_01505	COG0493	'glutamate synthase
M1S53_01515	COG1704	LemA family
M1S53_01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M1S53_01540	COG3307	-O-antigen
M1S53_01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1S53_01580	COG0194	GDP metabolic process
M1S53_01630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M1S53_01650	COG5380	lipid catabolic process
M1S53_01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M1S53_01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1S53_01685	COG0277	FAD linked oxidase domain protein
M1S53_01695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M1S53_01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S53_01715	COG1289	transmembrane transporter activity
M1S53_01725	COG0628	permease
M1S53_01730	COG1192	Involved in chromosome partitioning
M1S53_01760	COG0833	amino acid
M1S53_01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1S53_01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1S53_01780	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_01820	COG0583	DNA-binding transcription factor activity
M1S53_01865	COG0517	IMP dehydrogenase activity
M1S53_01870	COG1983	PspC domain protein
M1S53_01880	COG1960	acyl-CoA dehydrogenase activity
M1S53_01895	COG0408	coproporphyrinogen oxidase activity
M1S53_01915	COG0513	Belongs to the DEAD box helicase family
M1S53_01925	COG1127	ABC transporter
M1S53_01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M1S53_01940	COG2854	intermembrane phospholipid transfer
M1S53_01950	COG0598	Magnesium transport protein CorA
M1S53_01960	COG0494	nUDIX hydrolase
M1S53_01965	COG1040	competence protein
M1S53_01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1S53_01990	COG1946	Acyl-CoA thioesterase
M1S53_01995	COG1301	dicarboxylic acid transport
M1S53_02010	COG1959	2 iron, 2 sulfur cluster binding
M1S53_02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S53_02015	COG1017	nitric oxide dioxygenase activity
M1S53_02020	COG0433	COG0433 Predicted ATPase
M1S53_02025	COG0626	cystathionine gamma-synthase activity
M1S53_02180	COG1960	acyl-CoA dehydrogenase activity
M1S53_02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M1S53_02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M1S53_02220	COG0339	signal peptide processing
M1S53_02225	COG0557	exoribonuclease II activity
M1S53_02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1S53_02275	COG2169	Transcriptional regulator
M1S53_02280	COG0697	spore germination
M1S53_02285	COG1295	ribonuclease BN
M1S53_02320	COG1702	phosphate starvation-inducible protein PhoH
M1S53_02330	COG0739	heme binding
M1S53_02330	COG0741	lytic transglycosylase activity
M1S53_02330	COG1196	nuclear chromosome segregation
M1S53_02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M1S53_02365	COG1183	phosphatidylcholine synthase activity
M1S53_02410	COG1960	acyl-CoA dehydrogenase activity
M1S53_02415	COG1309	transcriptional regulator
M1S53_02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1S53_02435	COG1960	acyl-CoA dehydrogenase activity
M1S53_02455	COG2969	positive regulation of protein catabolic process
M1S53_02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M1S53_02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M1S53_02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M1S53_02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1S53_02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1S53_02520	COG1408	metallophosphoesterase
M1S53_02530	COG2199	diguanylate cyclase activity
M1S53_02590	COG1607	acyl-coa hydrolase
M1S53_02620	COG2350	Protein conserved in bacteria
M1S53_02630	COG0613	PHP domain protein
M1S53_02635	COG3781	membrane
M1S53_02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1S53_02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1S53_02660	COG1862	Preprotein translocase
M1S53_02690	COG2205	protein histidine kinase activity
M1S53_02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M1S53_02715	COG0726	polysaccharide deacetylase
M1S53_02720	COG0463	Glycosyl transferase, family 2
M1S53_02725	COG0438	transferase activity, transferring glycosyl groups
M1S53_02790	COG0625	glutathione transferase activity
M1S53_02795	COG0583	DNA-binding transcription factor activity
M1S53_02800	COG1960	acyl-CoA dehydrogenase activity
M1S53_02805	COG1960	acyl-CoA dehydrogenase activity
M1S53_02815	COG2205	protein histidine kinase activity
M1S53_02820	COG0745	RESPONSE REGULATOR receiver
M1S53_02825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M1S53_02845	COG2096	Adenosyltransferase
M1S53_02895	COG0285	dihydrofolate synthase activity
M1S53_02915	COG0450	alkyl hydroperoxide reductase
M1S53_02930	COG0477	Major facilitator Superfamily
M1S53_02935	COG1272	protein, Hemolysin III
M1S53_02965	COG0183	Belongs to the thiolase family
M1S53_02970	COG2207	Transcriptional regulator
M1S53_02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S53_03010	COG0183	Belongs to the thiolase family
M1S53_03020	COG2885	chlorophyll binding
M1S53_03020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M1S53_03035	COG0833	amino acid
M1S53_03045	COG2233	PERMEase
M1S53_03050	COG1217	gtp-binding protein TYPA
M1S53_03075	COG2094	Belongs to the DNA glycosylase MPG family
M1S53_03095	COG1902	pentaerythritol trinitrate reductase activity
M1S53_03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S53_03115	COG0354	folic acid binding
M1S53_03125	COG3189	MarR family transcriptional regulator
M1S53_03130	COG2824	Alkylphosphonate utilization operon protein PhnA
M1S53_03135	COG3422	double-strand break repair
M1S53_03175	COG0840	transmembrane signaling receptor activity
M1S53_03195	COG5510	response to toxic substance
M1S53_03205	COG2832	Protein of unknown function (DUF454)
M1S53_03210	COG1376	ErfK ybiS ycfS ynhG family protein
M1S53_03250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M1S53_03260	COG1289	transmembrane transporter activity
M1S53_03265	COG2814	Major facilitator Superfamily
M1S53_03285	COG1115	amino acid carrier protein
M1S53_03290	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1S53_03295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1S53_03300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
M1S53_03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1S53_03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1S53_03345	COG1077	Cell shape determining protein MreB Mrl
M1S53_03350	COG1792	Involved in formation and maintenance of cell shape
M1S53_03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M1S53_03360	COG0424	maF-like protein
M1S53_03365	COG1530	ribonuclease E activity
M1S53_03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S53_03385	COG0560	Phosphoserine phosphatase
M1S53_03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S53_03420	COG2207	Transcriptional regulator
M1S53_03440	COG1113	amino acid transport
M1S53_03445	COG2828	Protein conserved in bacteria
M1S53_03450	COG0142	geranyltranstransferase activity
M1S53_03455	COG2315	Protein conserved in bacteria
M1S53_03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1S53_03490	COG2194	sulfuric ester hydrolase activity
M1S53_03495	COG0745	RESPONSE REGULATOR receiver
M1S53_03500	COG0642	Histidine kinase
M1S53_03510	COG0004	ammonium transporteR
M1S53_03515	COG0583	DNA-binding transcription factor activity
M1S53_03535	COG0525	valine-tRNA ligase activity
M1S53_03545	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_03555	COG0393	Putative heavy-metal-binding
M1S53_03560	COG0393	Putative heavy-metal-binding
M1S53_03565	COG1538	Outer membrane efflux protein
M1S53_03575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S53_03580	COG0671	phosphoesterase, PA-phosphatase related
M1S53_03610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1S53_03625	COG1648	precorrin-2 dehydrogenase activity
M1S53_03625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1S53_03630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1S53_03635	COG1733	regulation of RNA biosynthetic process
M1S53_03645	COG0531	amino acid
M1S53_03660	COG0321	lipoyl(octanoyl) transferase activity
M1S53_03665	COG2921	Belongs to the UPF0250 family
M1S53_03705	COG2009	succinate dehydrogenase
M1S53_03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M1S53_03715	COG1053	succinate dehydrogenase
M1S53_03720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1S53_03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S53_03765	COG2354	Protein conserved in bacteria
M1S53_03770	COG2321	neutral zinc metallopeptidase
M1S53_03790	COG2843	Capsule synthesis protein
M1S53_03805	COG0589	response to stress
M1S53_03825	COG0505	Belongs to the CarA family
M1S53_03850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1S53_03855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1S53_03905	COG0477	Major facilitator Superfamily
M1S53_03910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M1S53_03925	COG1597	lipid kinase activity
M1S53_03930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1S53_03960	COG0584	glycerophosphoryl diester phosphodiesterase
M1S53_03980	COG0741	lytic transglycosylase activity
M1S53_04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M1S53_04015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S53_04045	COG0778	Nitroreductase
M1S53_04060	COG1929	Belongs to the glycerate kinase type-1 family
M1S53_04065	COG0243	molybdopterin cofactor binding
M1S53_04070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1S53_04075	COG3339	Conserved Protein
M1S53_04085	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
M1S53_04100	COG1113	amino acid transport
M1S53_04110	COG0019	diaminopimelate decarboxylase activity
M1S53_04120	COG1280	lysine exporter protein (LysE YggA)
M1S53_04125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1S53_04155	COG0463	Glycosyl transferase, family 2
M1S53_04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S53_04210	COG4591	ABC-type transport system involved in lipoprotein release permease component
M1S53_04215	COG1136	(ABC) transporter
M1S53_04220	COG2333	competence protein COMEC
M1S53_04220	COG0658	competence protein
M1S53_04230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M1S53_04230	COG0616	signal peptide processing
M1S53_04235	COG0596	Alpha beta hydrolase
M1S53_04240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1S53_04250	COG0628	permease
M1S53_04285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1S53_04305	COG0823	Involved in the tonB-independent uptake of proteins
M1S53_04325	COG0824	Thioesterase
M1S53_04330	COG1473	amidohydrolase
M1S53_04350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1S53_04350	COG0047	phosphoribosylformylglycinamidine synthase activity
M1S53_04355	COG2814	Major facilitator Superfamily
M1S53_04365	COG1024	Enoyl-CoA hydratase
M1S53_04370	COG1056	cytidyltransferase-related domain
M1S53_04370	COG1051	belongs to the nudix hydrolase family
M1S53_04380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1S53_04395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M1S53_04410	COG4625	pathogenesis
M1S53_04415	COG0583	DNA-binding transcription factor activity
M1S53_04420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M1S53_04425	COG4208	sulfate ABC transporter
M1S53_04430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M1S53_04440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M1S53_04445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1S53_04450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1S53_04470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1S53_04485	COG0681	Belongs to the peptidase S26 family
M1S53_04500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1S53_04510	COG1381	Involved in DNA repair and RecF pathway recombination
M1S53_04515	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M1S53_04525	COG4221	oxidoreductase activity
M1S53_04555	COG0436	Aminotransferase
M1S53_04575	COG0556	nucleotide-excision repair
M1S53_04630	COG2070	2-Nitropropane dioxygenase
M1S53_04660	COG1215	transferase activity, transferring glycosyl groups
M1S53_04675	COG0415	Belongs to the DNA photolyase family
M1S53_04685	COG1252	NADH dehydrogenase
M1S53_04690	COG1686	Belongs to the peptidase S11 family
M1S53_04705	COG1187	pseudouridine synthase activity
M1S53_04730	COG0477	Major facilitator Superfamily
M1S53_04735	COG0583	DNA-binding transcription factor activity
M1S53_04740	COG1823	symporter activity
M1S53_04750	COG0612	Peptidase, M16
M1S53_04775	COG0352	thiamine-phosphate diphosphorylase activity
M1S53_04810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S53_04825	COG1309	transcriptional regulator
M1S53_04835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1S53_04840	COG0076	glutamate decarboxylase activity
M1S53_04850	COG1522	sequence-specific DNA binding
M1S53_04855	COG3961	Belongs to the TPP enzyme family
M1S53_04860	COG1113	amino acid transport
M1S53_04865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1S53_04870	COG0573	inorganic phosphate transmembrane transporter activity
M1S53_04880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M1S53_04885	COG0616	signal peptide processing
M1S53_04920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1S53_04925	COG1686	Belongs to the peptidase S11 family
M1S53_04950	COG0583	DNA-binding transcription factor activity
M1S53_04955	COG1067	ATP-dependent peptidase activity
M1S53_05000	COG1966	Carbon starvation protein
M1S53_05005	COG2879	small protein
M1S53_05040	COG2508	Transcriptional regulator
M1S53_05040	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M1S53_05065	COG1113	amino acid transport
M1S53_05070	COG0583	DNA-binding transcription factor activity
M1S53_05075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S53_05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S53_05090	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_05100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S53_05105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
M1S53_05105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S53_05140	COG2814	Major facilitator Superfamily
M1S53_05145	COG4948	Mandelate Racemase Muconate Lactonizing
M1S53_05155	COG1309	transcriptional regulator
M1S53_05175	COG1741	Belongs to the pirin family
M1S53_05185	COG2964	Protein conserved in bacteria
M1S53_05200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S53_05205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1S53_05210	COG4605	iron ion homeostasis
M1S53_05215	COG4604	ABC transporter, ATP-binding protein
M1S53_05220	COG4607	ABC-type enterochelin transport system periplasmic component
M1S53_05225	COG4774	siderophore transport
M1S53_05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S53_05240	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1S53_05245	COG3433	isochorismatase activity
M1S53_05245	COG1535	isochorismatase
M1S53_05260	COG1132	(ABC) transporter
M1S53_05265	COG1132	(ABC) transporter
M1S53_05270	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M1S53_05280	COG1169	isochorismate synthase
M1S53_05295	COG3739	integral membrane protein
M1S53_05320	COG0302	gtp cyclohydrolase
M1S53_05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M1S53_05360	COG0308	aminopeptidase N
M1S53_05365	COG0512	Glutamine amidotransferase of anthranilate synthase
M1S53_05380	COG0174	glutamine synthetase
M1S53_05390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
M1S53_05425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1S53_05430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1S53_05435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1S53_05455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1S53_05460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1S53_05465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
M1S53_05480	COG1960	acyl-CoA dehydrogenase activity
M1S53_05485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1S53_05490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S53_05500	COG2223	nitrite transmembrane transporter activity
M1S53_05510	COG0024	Methionine aminopeptidase
M1S53_05515	COG0052	Belongs to the universal ribosomal protein uS2 family
M1S53_05530	COG2207	Transcriptional regulator
M1S53_05555	COG2951	lytic endotransglycosylase activity
M1S53_05560	COG0772	Belongs to the SEDS family
M1S53_05575	COG0842	Transport permease protein
M1S53_05580	COG1131	(ABC) transporter
M1S53_05625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S53_05640	COG4215	(ABC) transporter
M1S53_05645	COG4160	amino acid transport
M1S53_05650	COG4598	ABC transporter
M1S53_05660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1S53_05665	COG0826	peptidase U32
M1S53_05670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S53_05685	COG1720	tRNA m6t6A37 methyltransferase activity
M1S53_05695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1S53_05710	COG0642	Histidine kinase
M1S53_05720	COG0494	nUDIX hydrolase
M1S53_05730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1S53_05735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M1S53_05740	COG3139	Protein of unknown function (DUF1315)
M1S53_05745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M1S53_05750	COG1301	dicarboxylic acid transport
M1S53_05755	COG1960	acyl-CoA dehydrogenase activity
M1S53_05760	COG2819	hydrolase of the alpha beta superfamily
M1S53_05770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M1S53_05780	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1S53_05785	COG1234	tRNA 3'-trailer cleavage
M1S53_05815	COG2363	Small membrane protein
M1S53_05840	COG0513	Belongs to the DEAD box helicase family
M1S53_05850	COG0778	Nitroreductase
M1S53_06200	COG1286	toxin biosynthetic process
M1S53_06225	COG4783	chaperone-mediated protein folding
M1S53_06230	COG1610	YqeY-like protein
M1S53_06330	COG3111	PFAM Bacterial OB fold (BOF) protein
M1S53_06355	COG3243	poly(R)-hydroxyalkanoic acid synthase
M1S53_06360	COG0786	glutamate:sodium symporter activity
M1S53_06370	COG2186	Transcriptional regulator
M1S53_06435	COG1301	dicarboxylic acid transport
M1S53_06445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S53_06450	COG2011	ABC-type metal ion transport system permease component
M1S53_06455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1S53_06460	COG1464	Belongs to the NlpA lipoprotein family
M1S53_06465	COG0151	Belongs to the GarS family
M1S53_06470	COG0138	bifunctional purine biosynthesis protein purh
M1S53_06475	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M1S53_06505	COG2308	Evidence 4 Homologs of previously reported genes of
M1S53_06515	COG1305	Transglutaminase-like
M1S53_06525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1S53_06530	COG0305	Participates in initiation and elongation during chromosome replication
M1S53_06555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M1S53_06595	COG0726	polysaccharide deacetylase
M1S53_06595	COG1649	PFAM Uncharacterised BCR, COG1649
M1S53_06600	COG1215	transferase activity, transferring glycosyl groups
M1S53_06605	COG3658	cytochrome
M1S53_06615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S53_06630	COG0583	DNA-binding transcription factor activity
M1S53_06650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S53_06655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S53_06670	COG1960	acyl-CoA dehydrogenase activity
M1S53_06675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S53_06680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S53_06705	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M1S53_06710	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M1S53_06720	COG2205	protein histidine kinase activity
M1S53_06725	COG0745	RESPONSE REGULATOR receiver
M1S53_06730	COG0174	glutamine synthetase
M1S53_06750	COG0729	surface antigen
M1S53_06775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1S53_06780	COG2814	Major facilitator Superfamily
M1S53_06795	COG0583	DNA-binding transcription factor activity
M1S53_06810	COG1187	pseudouridine synthase activity
M1S53_06830	COG0802	atpase or kinase
M1S53_06835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M1S53_06845	COG1923	regulation of RNA biosynthetic process
M1S53_06850	COG0697	spore germination
M1S53_06865	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S53_06875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1S53_06880	COG0519	Catalyzes the synthesis of GMP from XMP
M1S53_06880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1S53_06885	COG4302	ethanolamine ammonia-lyase activity
M1S53_06890	COG4303	Ethanolamine ammonia lyase large subunit
M1S53_06895	COG0531	amino acid
M1S53_06915	COG1454	alcohol dehydrogenase
M1S53_06930	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M1S53_06950	COG0308	aminopeptidase N
M1S53_06970	COG1605	Chorismate mutase
M1S53_06990	COG1309	transcriptional regulator
M1S53_07000	COG0668	transmembrane transport
M1S53_07035	COG4773	Receptor
M1S53_07055	COG0488	(ABC) transporter
M1S53_07060	COG0589	response to stress
M1S53_07085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1S53_07095	COG3135	benzoate transporter
M1S53_07100	COG1522	sequence-specific DNA binding
M1S53_07110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M1S53_07115	COG0583	DNA-binding transcription factor activity
M1S53_07125	COG0183	Belongs to the thiolase family
M1S53_07135	COG2030	dehydratase
M1S53_07140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1S53_07155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1S53_07165	COG0824	Thioesterase
M1S53_07170	COG1454	alcohol dehydrogenase
M1S53_07180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1S53_07200	COG0069	glutamate synthase activity
M1S53_07380	COG5410	chromosome segregation
M1S53_07590	COG2814	Major facilitator Superfamily
M1S53_07605	COG0511	ligase activity, forming carbon-carbon bonds
M1S53_07625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S53_07625	COG1116	anion transmembrane transporter activity
M1S53_07630	COG0745	RESPONSE REGULATOR receiver
M1S53_07640	COG2146	nitrite reductase [NAD(P)H] activity
M1S53_07640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S53_07645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S53_07650	COG0243	molybdopterin cofactor binding
M1S53_07660	COG0243	molybdopterin cofactor binding
M1S53_07665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M1S53_07680	COG0315	cyclic pyranopterin monophosphate synthase activity
M1S53_07680	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1S53_07685	COG0303	'Molybdopterin
M1S53_07695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S53_07700	COG0697	spore germination
M1S53_07720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M1S53_07725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1S53_07790	COG2204	response regulator
M1S53_07795	COG3852	Histidine kinase
M1S53_07815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1S53_07820	COG0575	Belongs to the CDS family
M1S53_07855	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S53_07870	COG2137	regulation of response to DNA damage stimulus
M1S53_07880	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1S53_07885	COG1011	Hydrolase
M1S53_07910	COG1522	sequence-specific DNA binding
M1S53_07920	COG1113	amino acid transport
M1S53_07940	COG0659	secondary active sulfate transmembrane transporter activity
M1S53_07945	COG2135	peptidase activity
M1S53_07960	COG3300	MHYT domain
M1S53_07960	COG5001	Diguanylate cyclase
M1S53_07990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1S53_07990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1S53_07990	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M1S53_07995	COG1105	Belongs to the carbohydrate kinase PfkB family
M1S53_08000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M1S53_08000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1S53_08030	COG0024	Methionine aminopeptidase
M1S53_08035	COG0583	DNA-binding transcription factor activity
M1S53_08045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M1S53_08050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1S53_08055	COG0516	GMP reductase activity
M1S53_08055	COG0517	IMP dehydrogenase activity
M1S53_08080	COG0552	protein localization to endoplasmic reticulum
M1S53_08090	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M1S53_08105	COG4890	Cyd operon protein YbgT
M1S53_08110	COG1294	oxidase, subunit
M1S53_08125	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1S53_08135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1S53_08140	COG4774	siderophore transport
M1S53_08155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1S53_08160	COG0569	domain protein
M1S53_08165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1S53_08195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M1S53_08200	COG0542	response to heat
M1S53_08225	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S53_08225	COG1902	pentaerythritol trinitrate reductase activity
M1S53_08270	COG2323	membrane
M1S53_08275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M1S53_08285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S53_08290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S53_08295	COG0183	Belongs to the thiolase family
M1S53_08300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1S53_08305	COG0596	Alpha beta hydrolase
M1S53_08310	COG2271	Major facilitator Superfamily
M1S53_08315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1S53_08320	COG3485	protocatechuate 3,4-dioxygenase
M1S53_08325	COG3485	protocatechuate 3,4-dioxygenase
M1S53_08330	COG0710	3-dehydroquinate dehydratase activity
M1S53_08335	COG3420	alginic acid biosynthetic process
M1S53_08340	COG3659	wide pore channel activity
M1S53_08345	COG4993	Dehydrogenase
M1S53_08355	COG2391	methyltransferase activity
M1S53_08370	COG1414	Transcriptional regulator
M1S53_08375	COG0583	DNA-binding transcription factor activity
M1S53_08380	COG1960	acyl-CoA dehydrogenase activity
M1S53_08405	COG2814	Major facilitator Superfamily
M1S53_08415	COG0154	amidase activity
M1S53_08435	COG4638	Rieske (2fe-2S)
M1S53_08445	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_08455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S53_08465	COG3733	amine oxidase
M1S53_08475	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_08485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S53_08490	COG0183	Belongs to the thiolase family
M1S53_08495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S53_08500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S53_08510	COG4829	muconolactone delta-isomerase
M1S53_08515	COG4948	Mandelate Racemase Muconate Lactonizing
M1S53_08520	COG0583	DNA-binding transcription factor activity
M1S53_08530	COG2186	Transcriptional regulator
M1S53_08570	COG1960	acyl-CoA dehydrogenase activity
M1S53_08575	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_08580	COG3829	transcription factor binding
M1S53_08590	COG3162	membrane
M1S53_08605	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_08620	COG0753	catalase activity
M1S53_08640	COG1846	Transcriptional regulator
M1S53_08645	COG1902	pentaerythritol trinitrate reductase activity
M1S53_08645	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S53_08655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1S53_08685	COG1309	transcriptional regulator
M1S53_08695	COG1335	isochorismatase
M1S53_08700	COG0583	DNA-binding transcription factor activity
M1S53_08710	COG0475	glutathione-regulated potassium exporter activity
M1S53_08710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S53_08720	COG1473	amidohydrolase
M1S53_08730	COG2831	hemolysin activation secretion protein
M1S53_08735	COG3210	domain, Protein
M1S53_08765	COG2188	Transcriptional regulator
M1S53_08780	COG0583	DNA-binding transcription factor activity
M1S53_08810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1S53_08840	COG1566	PFAM secretion protein HlyD family protein
M1S53_08855	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_08860	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_08865	COG0129	dihydroxy-acid dehydratase activity
M1S53_08875	COG0583	DNA-binding transcription factor activity
M1S53_08880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1S53_08890	COG2084	Dehydrogenase
M1S53_08895	COG2207	Transcriptional regulator
M1S53_08910	COG1064	alcohol dehydrogenase
M1S53_08920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1S53_08925	COG1120	ATPase activity
M1S53_08945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1S53_09065	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
M1S53_09115	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_09130	COG2207	Transcriptional regulator
M1S53_09140	COG2205	protein histidine kinase activity
M1S53_09145	COG0745	RESPONSE REGULATOR receiver
M1S53_09150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S53_09155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1S53_09160	COG1538	Outer membrane efflux protein
M1S53_09170	COG2072	flavoprotein involved in K transport
M1S53_09190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S53_09210	COG3539	Fimbrial protein
M1S53_09240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
M1S53_09250	COG0753	catalase activity
M1S53_09265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1S53_09325	COG1535	isochorismatase
M1S53_09325	COG3433	isochorismatase activity
M1S53_09330	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_09335	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
M1S53_09340	COG4149	molybdate abc transporter
M1S53_09345	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1S53_09355	COG4638	Rieske (2fe-2S)
M1S53_09360	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1S53_09365	COG0543	2 iron, 2 sulfur cluster binding
M1S53_09365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S53_09390	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_09405	COG2207	Transcriptional regulator
M1S53_09415	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_09420	COG2610	gluconate transmembrane transporter activity
M1S53_09430	COG0583	DNA-binding transcription factor activity
M1S53_09440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S53_09445	COG2031	fatty acid transporter
M1S53_09450	COG0183	Belongs to the thiolase family
M1S53_09455	COG0583	DNA-binding transcription factor activity
M1S53_09460	COG0583	DNA-binding transcription factor activity
M1S53_09475	COG1027	Aspartate ammonia-lyase
M1S53_09485	COG0477	Major facilitator Superfamily
M1S53_09505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S53_09510	COG4521	taurine ABC transporter
M1S53_09525	COG2188	Transcriptional regulator
M1S53_09535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1S53_09540	COG1733	regulation of RNA biosynthetic process
M1S53_09545	COG3708	Transcriptional regulator
M1S53_09545	COG2207	Transcriptional regulator
M1S53_09560	COG0730	response to heat
M1S53_09575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S53_09575	COG3453	Protein conserved in bacteria
M1S53_09585	COG3781	membrane
M1S53_09590	COG1063	alcohol dehydrogenase
M1S53_09600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S53_09605	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1S53_09610	COG0022	dehydrogenase e1 component
M1S53_09615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1S53_09620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1S53_09635	COG3706	GGDEF domain
M1S53_09650	COG0133	tryptophan synthase activity
M1S53_09660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1S53_09695	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M1S53_09720	COG2226	methyltransferase
M1S53_09775	COG0842	Transport permease protein
M1S53_09780	COG0842	Transport permease protein
M1S53_09785	COG1131	(ABC) transporter
M1S53_09800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S53_09805	COG4773	Receptor
M1S53_09825	COG0730	response to heat
M1S53_09830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M1S53_09850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
M1S53_09865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1S53_09905	COG4264	IucA IucC family
M1S53_09910	COG4264	IucA IucC family
M1S53_09930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1S53_09945	COG1960	acyl-CoA dehydrogenase activity
M1S53_09950	COG1960	acyl-CoA dehydrogenase activity
M1S53_09955	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1S53_09960	COG2207	Transcriptional regulator
M1S53_09965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1S53_09970	COG0776	regulation of translation
M1S53_09995	COG0822	iron-sulfur transferase activity
M1S53_10000	COG0316	Belongs to the HesB IscA family
M1S53_10030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1S53_10050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1S53_10055	COG0702	epimerase
M1S53_10090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1S53_10100	COG0339	signal peptide processing
M1S53_10150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M1S53_10155	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M1S53_10185	COG0776	regulation of translation
M1S53_10250	COG0084	hydrolase, TatD family'
M1S53_10270	COG1663	tetraacyldisaccharide 4'-kinase activity
M1S53_10275	COG1132	(ABC) transporter
M1S53_10285	COG0811	peptide transport
M1S53_10290	COG1475	DNA binding
M1S53_10295	COG1192	Involved in chromosome partitioning
M1S53_10305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1S53_10320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1S53_10325	COG0191	fructose-bisphosphate aldolase activity
M1S53_10345	COG0424	maF-like protein
M1S53_10350	COG2850	peptidyl-arginine hydroxylation
M1S53_10360	COG0640	Transcriptional regulator
M1S53_10370	COG3619	membrane
M1S53_10375	COG3122	Protein conserved in bacteria
M1S53_10380	COG1132	(ABC) transporter
M1S53_10400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1S53_10405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1S53_10415	COG0506	proline dehydrogenase activity
M1S53_10415	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M1S53_10415	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M1S53_10420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1S53_10435	COG3698	Phosphodiester glycosidase
M1S53_10445	COG2353	YceI-like domain
M1S53_10455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M1S53_10500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M1S53_10500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M1S53_10525	COG3539	Fimbrial protein
M1S53_10530	COG3121	Chaperone
M1S53_10555	COG0697	spore germination
M1S53_10565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1S53_10575	COG0583	DNA-binding transcription factor activity
M1S53_10595	COG1309	transcriptional regulator
M1S53_10610	COG1522	sequence-specific DNA binding
M1S53_10625	COG1126	abc transporter atp-binding protein
M1S53_10630	COG0765	amino acid transport
M1S53_10635	COG0765	amino acid transport
M1S53_10665	COG1464	Belongs to the NlpA lipoprotein family
M1S53_10685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1S53_10690	COG2011	ABC-type metal ion transport system permease component
M1S53_10695	COG0012	GTP binding
M1S53_10720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1S53_10760	COG0386	Belongs to the glutathione peroxidase family
M1S53_10770	COG0436	Aminotransferase
M1S53_10825	COG0583	DNA-binding transcription factor activity
M1S53_10830	COG0798	PFAM Bile acid sodium symporter
M1S53_10835	COG0640	Transcriptional regulator
M1S53_10850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1S53_10860	COG0583	DNA-binding transcription factor activity
M1S53_10870	COG1953	Uracil, thiamine, allantoin
M1S53_10880	COG2175	clavaminate synthase activity
M1S53_10885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S53_10890	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
M1S53_10895	COG4521	taurine ABC transporter
M1S53_10905	COG0477	Major facilitator Superfamily
M1S53_10925	COG1271	oxidase subunit
M1S53_10930	COG1294	oxidase, subunit
M1S53_10940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S53_10960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1S53_10980	COG3052	prosthetic group binding
M1S53_10985	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
M1S53_10995	COG2814	Major facilitator Superfamily
M1S53_11015	COG1346	cytolysis
M1S53_11025	COG0583	DNA-binding transcription factor activity
M1S53_11030	COG0625	glutathione transferase activity
M1S53_11035	COG0625	glutathione transferase activity
M1S53_11040	COG0583	DNA-binding transcription factor activity
M1S53_11055	COG1045	serine acetyltransferase
M1S53_11060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1S53_11065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1S53_11075	COG1280	lysine exporter protein (LysE YggA)
M1S53_11090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S53_11095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S53_11100	COG1126	abc transporter atp-binding protein
M1S53_11105	COG0765	amino acid transport
M1S53_11110	COG0765	amino acid transport
M1S53_11130	COG0784	Response regulator, receiver
M1S53_11130	COG2205	protein histidine kinase activity
M1S53_11150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M1S53_11170	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_11220	COG0583	DNA-binding transcription factor activity
M1S53_11240	COG0318	PFAM AMP-dependent synthetase and ligase
M1S53_11245	COG1309	transcriptional regulator
M1S53_11250	COG1960	acyl-CoA dehydrogenase activity
M1S53_11255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1S53_11260	COG1024	Enoyl-CoA hydratase
M1S53_11265	COG4770	biotin carboxylase activity
M1S53_11275	COG0583	DNA-binding transcription factor activity
M1S53_11290	COG1960	acyl-CoA dehydrogenase activity
M1S53_11300	COG2814	Major facilitator Superfamily
M1S53_11310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S53_11315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S53_11320	COG2814	Major facilitator Superfamily
M1S53_11325	COG1960	acyl-CoA dehydrogenase activity
M1S53_11330	COG1024	Enoyl-CoA hydratase
M1S53_11335	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_11340	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S53_11345	COG0183	Belongs to the thiolase family
M1S53_11355	COG2814	Major facilitator Superfamily
M1S53_11365	COG1024	Enoyl-CoA hydratase
M1S53_11380	COG1960	acyl-CoA dehydrogenase activity
M1S53_11385	COG2814	Major facilitator Superfamily
M1S53_11390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1S53_11395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1S53_11410	COG3842	ATPase activity
M1S53_11415	COG1840	ABC-type Fe3 transport system, periplasmic component
M1S53_11425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S53_11430	COG1414	Transcriptional regulator
M1S53_11440	COG0583	DNA-binding transcription factor activity
M1S53_11445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1S53_11450	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_11460	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1S53_11470	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_11475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S53_11480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S53_11485	COG2267	carboxylic ester hydrolase activity
M1S53_11505	COG3038	cytochrome b561
M1S53_11510	COG0753	catalase activity
M1S53_11545	COG2050	protein possibly involved in aromatic compounds catabolism
M1S53_11555	COG3327	negative regulation of DNA-templated transcription, initiation
M1S53_11560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
M1S53_11565	COG0183	Belongs to the thiolase family
M1S53_11570	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S53_11575	COG1024	Enoyl-CoA hydratase
M1S53_11580	COG1024	Enoyl-CoA hydratase
M1S53_11585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S53_11590	COG2151	metal-sulfur cluster biosynthetic enzyme
M1S53_11595	COG3396	Phenylacetate-CoA oxygenase
M1S53_11600	COG3460	Phenylacetate-CoA oxygenase
M1S53_11605	COG3396	Phenylacetate-CoA oxygenase
M1S53_11610	COG2030	dehydratase
M1S53_11610	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_11615	COG1760	l-serine dehydratase
M1S53_11620	COG0531	amino acid
M1S53_11625	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_11640	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S53_11650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S53_11670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S53_11680	COG0789	Transcriptional regulator
M1S53_11695	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1S53_11710	COG2807	transmembrane transport
M1S53_11715	COG0590	tRNA wobble adenosine to inosine editing
M1S53_11835	COG1116	anion transmembrane transporter activity
M1S53_11840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S53_11850	COG0864	Transcriptional regulator
M1S53_11870	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S53_11875	COG0439	Biotin carboxylase
M1S53_11890	COG1063	alcohol dehydrogenase
M1S53_11900	COG1309	transcriptional regulator
M1S53_11920	COG0038	chloride channel
M1S53_11925	COG4770	biotin carboxylase activity
M1S53_11945	COG1914	H( )-stimulated, divalent metal cation uptake system
M1S53_11950	COG0583	DNA-binding transcription factor activity
M1S53_12000	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S53_12020	COG2814	Major facilitator Superfamily
M1S53_12035	COG1560	Kdo2-lipid A biosynthetic process
M1S53_12045	COG5006	permease, DMT superfamily
M1S53_12050	COG1522	sequence-specific DNA binding
M1S53_12065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
M1S53_12075	COG4122	O-methyltransferase activity
M1S53_12105	COG1538	Outer membrane efflux protein
M1S53_12110	COG1137	ATPase activity
M1S53_12115	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M1S53_12125	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M1S53_12130	COG0517	IMP dehydrogenase activity
M1S53_12130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M1S53_12175	COG2814	Major facilitator Superfamily
M1S53_12210	COG1278	Cold shock
M1S53_12215	COG1280	lysine exporter protein (LysE YggA)
M1S53_12245	COG1570	exodeoxyribonuclease VII activity
M1S53_12295	COG0583	DNA-binding transcription factor activity
M1S53_12305	COG4638	Rieske (2fe-2S)
M1S53_12310	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1S53_12315	COG0633	Ferredoxin
M1S53_12315	COG0543	2 iron, 2 sulfur cluster binding
M1S53_12320	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_12325	COG3135	benzoate transporter
M1S53_12330	COG2814	Major facilitator Superfamily
M1S53_12345	COG1643	Atp-dependent helicase
M1S53_12350	COG0450	alkyl hydroperoxide reductase
M1S53_12360	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
M1S53_12390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M1S53_12395	COG0625	glutathione transferase activity
M1S53_12405	COG2885	chlorophyll binding
M1S53_12440	COG0542	response to heat
M1S53_12455	COG1765	OsmC-like protein
M1S53_12475	COG0667	Aldo Keto reductase
M1S53_12490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M1S53_12500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1S53_12510	COG0527	aspartate kinase activity
M1S53_12520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M1S53_12530	COG3038	cytochrome b561
M1S53_12535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
M1S53_12540	COG2252	PERMEase
M1S53_12550	COG2072	flavoprotein involved in K transport
M1S53_12565	COG1741	Belongs to the pirin family
M1S53_12570	COG1309	transcriptional regulator
M1S53_12580	COG0300	oxidoreductase activity
M1S53_12690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1S53_12735	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_12755	COG0531	amino acid
M1S53_12765	COG1113	amino acid transport
M1S53_12805	COG3209	COG3209 Rhs family protein
M1S53_12835	COG4269	membrane
M1S53_12850	COG1902	pentaerythritol trinitrate reductase activity
M1S53_12850	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S53_12860	COG4251	negative regulation of phosphorylation
M1S53_12860	COG5001	Diguanylate cyclase
M1S53_12860	COG2203	Gaf domain
M1S53_12860	COG3706	GGDEF domain
M1S53_12870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S53_12890	COG4172	Belongs to the ABC transporter superfamily
M1S53_12895	COG4239	(ABC) transporter, permease
M1S53_12900	COG4174	ABC transporter (Permease)
M1S53_12910	COG0741	lytic transglycosylase activity
M1S53_12910	COG1388	LysM domain
M1S53_12910	COG1388	LysM domain
M1S53_12910	COG0741	lytic transglycosylase activity
M1S53_12915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S53_12955	COG0583	DNA-binding transcription factor activity
M1S53_12960	COG1279	arginine transmembrane transporter activity
M1S53_12980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S53_12985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S53_12990	COG0006	proline dipeptidase activity
M1S53_13075	COG0741	lytic transglycosylase activity
M1S53_13075	COG0739	heme binding
M1S53_13075	COG1196	nuclear chromosome segregation
M1S53_13135	COG4695	Portal protein
M1S53_13235	COG0305	Participates in initiation and elongation during chromosome replication
M1S53_13250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M1S53_13305	COG2194	sulfuric ester hydrolase activity
M1S53_13350	COG0739	heme binding
M1S53_13675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1S53_13700	COG3384	dioxygenase
M1S53_13715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1S53_13720	COG2878	Part of a membrane complex involved in electron transport
M1S53_13725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1S53_13750	COG0768	penicillin binding
M1S53_13755	COG0742	ribosomal rna small subunit methyltransferase
M1S53_13770	COG0830	nickel cation binding
M1S53_13820	COG1253	flavin adenine dinucleotide binding
M1S53_13825	COG2851	Citrate transporter
M1S53_13875	COG1773	rubredoxin
M1S53_13880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S53_13890	COG0583	DNA-binding transcription factor activity
M1S53_13915	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M1S53_13920	COG4181	ATPase activity
M1S53_13965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
M1S53_13985	COG0306	phosphate transporter
M1S53_13995	COG3958	Transketolase
M1S53_14000	COG3959	Transketolase, thiamine diphosphate binding domain
M1S53_14005	COG2271	Major facilitator Superfamily
M1S53_14010	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_14015	COG0583	DNA-binding transcription factor activity
M1S53_14030	COG2223	nitrite transmembrane transporter activity
M1S53_14035	COG2207	Transcriptional regulator
M1S53_14040	COG2066	Belongs to the glutaminase family
M1S53_14045	COG0242	peptide deformylase activity
M1S53_14050	COG0477	Major facilitator Superfamily
M1S53_14060	COG0028	Belongs to the TPP enzyme family
M1S53_14075	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_14080	COG2267	carboxylic ester hydrolase activity
M1S53_14090	COG2271	Major facilitator Superfamily
M1S53_14095	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S53_14105	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_14125	COG1414	Transcriptional regulator
M1S53_14140	COG1024	Enoyl-CoA hydratase
M1S53_14150	COG1215	transferase activity, transferring glycosyl groups
M1S53_14155	COG0726	polysaccharide deacetylase
M1S53_14155	COG1649	PFAM Uncharacterised BCR, COG1649
M1S53_14165	COG4681	YaeQ
M1S53_14175	COG0523	cobalamin synthesis protein
M1S53_14185	COG1607	acyl-coa hydrolase
M1S53_14195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S53_14200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S53_14205	COG1309	transcriptional regulator
M1S53_14230	COG2040	homocysteine
M1S53_14235	COG0531	amino acid
M1S53_14290	COG1595	DNA-templated transcription, initiation
M1S53_14300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S53_14305	COG0477	Major facilitator Superfamily
M1S53_14325	COG0084	hydrolase, TatD family'
M1S53_14360	COG0629	single-stranded DNA binding
M1S53_14415	COG0582	viral genome integration into host DNA
M1S53_14445	COG1061	Type III restriction enzyme res subunit
M1S53_14455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1S53_14460	COG1192	Involved in chromosome partitioning
M1S53_14470	COG1061	Type III restriction enzyme res subunit
M1S53_14560	COG0592	DNA-directed DNA polymerase activity
M1S53_14600	COG2026	Addiction module toxin, RelE StbE family
M1S53_14750	COG3755	Protein conserved in bacteria
M1S53_14795	COG1484	DNA-dependent DNA replication
M1S53_14885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S53_14955	COG0405	Gamma-glutamyltransferase
M1S53_14960	COG2814	Major facilitator Superfamily
M1S53_14970	COG2050	protein possibly involved in aromatic compounds catabolism
M1S53_14985	COG1090	epimerase
M1S53_15005	COG0420	3'-5' exonuclease activity
M1S53_15030	COG0735	belongs to the Fur family
M1S53_15035	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M1S53_15055	COG0121	glutamine amidotransferase
M1S53_15070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S53_15080	COG0210	DNA helicase
M1S53_15085	COG2885	chlorophyll binding
M1S53_15090	COG0204	Acyl-transferase
M1S53_15105	COG2894	cell division
M1S53_15130	COG1280	lysine exporter protein (LysE YggA)
M1S53_15135	COG1674	ftsk spoiiie
M1S53_15135	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M1S53_15145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
M1S53_15155	COG0456	acetyltransferase
M1S53_15200	COG1981	membrane
M1S53_15215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M1S53_15215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1S53_15235	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_15245	COG0657	acetylesterase activity
M1S53_15255	COG0473	3-isopropylmalate dehydrogenase activity
M1S53_15260	COG0583	DNA-binding transcription factor activity
M1S53_15280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1S53_15305	COG0564	pseudouridine synthase activity
M1S53_15315	COG0358	DNA primase activity
M1S53_15330	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
M1S53_15360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1S53_15390	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M1S53_15400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1S53_15400	COG0352	thiamine-phosphate diphosphorylase activity
M1S53_15400	COG0351	phosphomethylpyrimidine kinase
M1S53_15405	COG1652	LysM domain
M1S53_15430	COG1399	metal-binding, possibly nucleic acid-binding protein
M1S53_15440	COG0009	L-threonylcarbamoyladenylate synthase
M1S53_15445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M1S53_15450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M1S53_15465	COG4106	trans-aconitate 2-methyltransferase activity
M1S53_15480	COG0596	Alpha beta hydrolase
M1S53_15480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S53_15480	COG2226	methyltransferase
M1S53_15485	COG1877	trehalose-phosphatase activity
M1S53_15490	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
M1S53_15495	COG2223	nitrite transmembrane transporter activity
M1S53_15515	COG1196	nuclear chromosome segregation
M1S53_15525	COG0730	response to heat
M1S53_15540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1S53_15550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1S53_15600	COG0489	protein tyrosine kinase activity
M1S53_15610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S53_15610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S53_15640	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M1S53_15645	COG2081	HI0933 family
M1S53_15655	COG0668	transmembrane transport
M1S53_15675	COG0583	DNA-binding transcription factor activity
M1S53_15695	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1S53_15700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1S53_15730	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M1S53_15770	COG0745	RESPONSE REGULATOR receiver
M1S53_15790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1S53_15800	COG2205	protein histidine kinase activity
M1S53_15870	COG4993	Dehydrogenase
M1S53_15895	COG0384	phenazine biosynthesis protein PhzF
M1S53_15920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S53_15935	COG0583	DNA-binding transcription factor activity
M1S53_15965	COG0583	DNA-binding transcription factor activity
M1S53_15980	COG0583	DNA-binding transcription factor activity
M1S53_15985	COG1053	succinate dehydrogenase
M1S53_15995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M1S53_16000	COG2814	Major facilitator Superfamily
M1S53_16005	COG1960	acyl-CoA dehydrogenase activity
M1S53_16010	COG0583	DNA-binding transcription factor activity
M1S53_16015	COG1063	alcohol dehydrogenase
M1S53_16045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M1S53_16050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1S53_16055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1S53_16070	COG3667	copper resistance
M1S53_16075	COG2132	Multicopper oxidase
M1S53_16085	COG0561	phosphatase activity
M1S53_16090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1S53_16115	COG1214	PFAM Peptidase M22, glycoprotease
M1S53_16165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1S53_16175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1S53_16180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M1S53_16185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M1S53_16245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1S53_16255	COG1846	Transcriptional regulator
M1S53_16260	COG1764	response to oxidative stress
M1S53_16300	COG0037	tRNA processing
M1S53_16310	COG0248	Ppx GppA phosphatase
M1S53_16385	COG1238	metal cluster binding
M1S53_16390	COG0625	glutathione transferase activity
M1S53_16405	COG0318	PFAM AMP-dependent synthetase and ligase
M1S53_16410	COG3028	Belongs to the UPF0307 family
M1S53_16415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1S53_16435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1S53_16440	COG0617	tRNA 3'-terminal CCA addition
M1S53_16445	COG1555	photosystem II stabilization
M1S53_16450	COG3956	TIGRFAM MazG family protein
M1S53_16460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1S53_16480	COG0784	Response regulator, receiver
M1S53_16480	COG2205	protein histidine kinase activity
M1S53_16480	COG5002	protein histidine kinase activity
M1S53_16485	COG1024	Enoyl-CoA hydratase
M1S53_16490	COG2084	Dehydrogenase
M1S53_16495	COG3622	Belongs to the hyi family
M1S53_16525	COG0697	spore germination
M1S53_16535	COG2814	Major facilitator Superfamily
M1S53_16540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1S53_16550	COG0583	DNA-binding transcription factor activity
M1S53_16560	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1S53_16575	COG0084	hydrolase, TatD family'
M1S53_16590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M1S53_16620	COG0440	acetolactate synthase activity
M1S53_16625	COG0028	Belongs to the TPP enzyme family
M1S53_16650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S53_16655	COG0577	efflux transmembrane transporter activity
M1S53_16655	COG1136	(ABC) transporter
M1S53_16660	COG1538	Outer membrane efflux protein
M1S53_16675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M1S53_16680	COG1162	GTPase activity
M1S53_16690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M1S53_16710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1S53_16715	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_16755	COG2986	histidine ammonia-lyase
M1S53_16770	COG0318	PFAM AMP-dependent synthetase and ligase
M1S53_16780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1S53_16825	COG1426	Protein conserved in bacteria
M1S53_16860	COG0793	Belongs to the peptidase S41A family
M1S53_16875	COG2267	carboxylic ester hydrolase activity
M1S53_16885	COG1012	belongs to the aldehyde dehydrogenase family
M1S53_16890	COG3265	gluconokinase activity
M1S53_16900	COG0800	Aldolase
M1S53_16910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M1S53_16915	COG0857	belongs to the CobB CobQ family
M1S53_16915	COG0280	phosphate acetyltransferase
M1S53_16920	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M1S53_16920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M1S53_16940	COG0740	serine-type endopeptidase activity
M1S53_16950	COG4774	siderophore transport
M1S53_16960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1S53_16970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S53_16970	COG2813	Specifically methylates the guanine in position
M1S53_17070	COG0788	formyltetrahydrofolate deformylase activity
M1S53_17095	COG4651	solute:proton antiporter activity
M1S53_17095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S53_17115	COG0724	RNA recognition motif
M1S53_17120	COG0210	DNA helicase
M1S53_17145	COG1733	regulation of RNA biosynthetic process
M1S53_17155	COG2900	Belongs to the SlyX family
M1S53_17160	COG0488	(ABC) transporter
M1S53_17165	COG1280	lysine exporter protein (LysE YggA)
M1S53_17170	COG1560	Kdo2-lipid A biosynthetic process
M1S53_17180	COG1301	dicarboxylic acid transport
M1S53_17235	COG0473	3-isopropylmalate dehydrogenase activity
M1S53_17300	COG0583	DNA-binding transcription factor activity
M1S53_17310	COG0625	glutathione transferase activity
M1S53_17315	COG2378	regulation of single-species biofilm formation
M1S53_17320	COG0546	phosphoglycolate phosphatase activity
M1S53_17330	COG1530	ribonuclease E activity
M1S53_17335	COG0318	PFAM AMP-dependent synthetase and ligase
M1S53_17350	COG0583	DNA-binding transcription factor activity
M1S53_17355	COG4221	oxidoreductase activity
M1S53_17360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1S53_17370	COG0534	Mate efflux family protein
M1S53_17385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
M1S53_17425	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
M1S53_17430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S53_17445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1S53_17455	COG0644	oxidoreductase
M1S53_17455	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
M1S53_17460	COG0425	Belongs to the sulfur carrier protein TusA family
M1S53_17465	COG4535	Mg2 and Co2 transporter CorC
M1S53_17475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S53_17495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1S53_17500	COG0475	glutathione-regulated potassium exporter activity
M1S53_17500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S53_17505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M1S53_17515	COG0484	heat shock protein binding
M1S53_17520	COG0789	Transcriptional regulator
M1S53_17525	COG0598	Magnesium transport protein CorA
M1S53_17540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1S53_17545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1S53_17550	COG1074	ATP-dependent DNA helicase activity
M1S53_17555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M1S53_17575	COG2226	methyltransferase
M1S53_17590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S53_17595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M1S53_17610	COG2111	Na H antiporter
M1S53_17610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1S53_17615	COG1006	Multisubunit Na H antiporter MnhC subunit
M1S53_17620	COG0651	ATP synthesis coupled electron transport
M1S53_17625	COG1863	multisubunit Na H antiporter MnhE subunit
M1S53_17630	COG2212	antiporter activity
M1S53_17635	COG1320	monovalent cation:proton antiporter activity
M1S53_17650	COG0195	Participates in both transcription termination and antitermination
M1S53_17700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1S53_17705	COG0237	dephospho-CoA kinase activity
M1S53_17715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1S53_17730	COG0497	DNA recombination
M1S53_17740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M1S53_17770	COG2169	Transcriptional regulator
M1S53_17770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1S53_17775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1S53_17840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1S53_17855	COG0326	Molecular chaperone. Has ATPase activity
M1S53_17870	COG2056	Na+-H+ antiporter family
M1S53_17875	COG0596	Alpha beta hydrolase
M1S53_17970	COG0546	phosphoglycolate phosphatase activity
M1S53_17975	COG1716	ATPase activity
M1S53_18020	COG0181	hydroxymethylbilane synthase activity
M1S53_18030	COG3275	phosphorelay sensor kinase activity
M1S53_18050	COG1538	Outer membrane efflux protein
M1S53_18055	COG0697	spore germination
M1S53_18080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1S53_18085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1S53_18090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1S53_18095	COG0772	Belongs to the SEDS family
M1S53_18120	COG4974	Belongs to the 'phage' integrase family
M1S53_18125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S53_18135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M1S53_18145	COG2197	response regulator
M1S53_18160	COG0793	Belongs to the peptidase S41A family
M1S53_18165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M1S53_18170	COG0795	lipopolysaccharide-transporting ATPase activity
M1S53_18210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1S53_18210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1S53_18220	COG0004	ammonium transporteR
M1S53_18225	COG0347	Belongs to the P(II) protein family
M1S53_18285	COG0659	secondary active sulfate transmembrane transporter activity
M1S53_18290	COG0589	response to stress
M1S53_18325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S53_18335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S53_18355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M1S53_18370	COG0318	PFAM AMP-dependent synthetase and ligase
M1S53_18380	COG0477	Major facilitator Superfamily
M1S53_18385	COG2860	membrane
M1S53_18395	COG1253	flavin adenine dinucleotide binding
M1S53_18415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1S53_18455	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1S53_18465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1S53_18535	COG0758	DNA mediated transformation
M1S53_18545	COG0697	spore germination
M1S53_18550	COG1309	transcriptional regulator
M1S53_18565	COG0386	Belongs to the glutathione peroxidase family
M1S53_18630	COG1121	(ABC) transporter
M1S53_18635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1S53_18640	COG1280	lysine exporter protein (LysE YggA)
M1S53_18645	COG2837	iron assimilation
M1S53_18655	COG0281	malic enzyme
M1S53_18700	COG0519	Catalyzes the synthesis of GMP from XMP
M1S53_18700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1S53_18705	COG4399	Belongs to the UPF0754 family
M1S53_18710	COG2259	Doxx family
M1S53_18715	COG0586	Pfam SNARE associated Golgi protein
M1S53_18730	COG1192	Involved in chromosome partitioning
M1S53_18740	COG0271	Belongs to the BolA IbaG family
M1S53_18760	COG2267	carboxylic ester hydrolase activity
M1S53_18780	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M1S53_18780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1S53_18780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M1S53_18780	COG3321	synthase
M1S53_18785	COG1960	acyl-CoA dehydrogenase activity
M1S53_18795	COG2197	response regulator
M1S53_18805	COG3916	Acyl-homoserine-lactone synthase
M1S53_18810	COG0477	Major facilitator Superfamily
M1S53_18815	COG1024	Enoyl-CoA hydratase
M1S53_18820	COG1024	Enoyl-CoA hydratase
M1S53_18825	COG1960	acyl-CoA dehydrogenase activity
M1S53_18830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S53_18850	COG1113	amino acid transport
M1S53_18855	COG1113	amino acid transport
M1S53_18860	COG0251	oxidation-reduction process
M1S53_18900	COG0564	pseudouridine synthase activity
M1S53_18960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1S53_18975	COG1802	Transcriptional regulator
M1S53_18985	COG1448	Aminotransferase
M1S53_18990	COG0277	FAD linked oxidase domain protein
M1S53_19000	COG2186	Transcriptional regulator
M1S53_19010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S53_19015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1S53_19030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1S53_19035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1S53_19040	COG1216	Glycosyl transferase, family 2
M1S53_19070	COG2089	acid synthase
M1S53_19085	COG1083	cytidylyl-transferase
M1S53_19090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M1S53_19095	COG1086	Polysaccharide biosynthesis protein
M1S53_19100	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M1S53_19105	COG1596	polysaccharide export
M1S53_19130	COG0728	peptidoglycan biosynthetic process
M1S53_19135	COG3023	N-Acetylmuramoyl-L-alanine amidase
M1S53_19195	COG0546	phosphoglycolate phosphatase activity
M1S53_19200	COG1028	Short-chain dehydrogenase reductase Sdr
M1S53_19220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S53_19225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S53_19230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S53_19235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S53_19240	COG1116	anion transmembrane transporter activity
M1S53_19245	COG1309	transcriptional regulator
M1S53_19250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M1S53_19260	COG0196	riboflavin kinase activity
M1S53_19265	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1S53_19275	COG1047	Peptidyl-prolyl cis-trans
M1S53_19315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1S53_19320	COG0657	acetylesterase activity
M1S53_19340	COG0583	DNA-binding transcription factor activity
M1S53_19370	COG2951	lytic endotransglycosylase activity
M1S53_19375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1S53_19390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M1S53_19400	COG0671	phosphoesterase, PA-phosphatase related
M1S53_19405	COG0861	Integral membrane protein TerC family
M1S53_19415	COG0754	glutathionylspermidine amidase activity
M1S53_19425	COG0402	S-adenosylhomocysteine deaminase activity
M1S53_19440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S53_19445	COG1230	cation diffusion facilitator family transporter
M1S53_19460	COG0706	membrane insertase activity