locus-tag	class	description
M1S33_00010	COG0592	DNA-directed DNA polymerase activity
M1S33_00020	COG0187	DNA topoisomerase II activity
M1S33_00030	COG0586	Pfam SNARE associated Golgi protein
M1S33_00035	COG0488	(ABC) transporter
M1S33_00060	COG0596	Alpha beta hydrolase
M1S33_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
M1S33_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M1S33_00110	COG0733	neurotransmitter:sodium symporter activity
M1S33_00150	COG2233	PERMEase
M1S33_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S33_00200	COG2814	Major facilitator Superfamily
M1S33_00205	COG0656	L-ascorbic acid biosynthetic process
M1S33_00210	COG0583	DNA-binding transcription factor activity
M1S33_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S33_00230	COG1064	alcohol dehydrogenase
M1S33_00235	COG2818	Glycosylase
M1S33_00250	COG1194	a g-specific adenine glycosylase
M1S33_00270	COG2983	Belongs to the UPF0260 family
M1S33_00275	COG2133	pyrroloquinoline quinone binding
M1S33_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1S33_00285	COG2116	formate transmembrane transporter activity
M1S33_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S33_00310	COG1335	isochorismatase
M1S33_00315	COG0385	Bile acid
M1S33_00320	COG0534	Mate efflux family protein
M1S33_00325	COG1683	Conserved Protein
M1S33_00345	COG0625	glutathione transferase activity
M1S33_00355	COG1113	amino acid transport
M1S33_00365	COG0523	cobalamin synthesis protein
M1S33_00375	COG2188	Transcriptional regulator
M1S33_00405	COG0010	Belongs to the arginase family
M1S33_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1S33_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M1S33_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1S33_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M1S33_00540	COG0534	Mate efflux family protein
M1S33_00545	COG0436	Aminotransferase
M1S33_00550	COG2733	membrane
M1S33_00565	COG2918	glutathione biosynthetic process
M1S33_00580	COG1388	LysM domain
M1S33_00580	COG0791	NLP P60 protein
M1S33_00595	COG3150	esterase
M1S33_00605	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
M1S33_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S33_00630	COG2233	PERMEase
M1S33_00635	COG2351	hydroxyisourate hydrolase activity
M1S33_00670	COG3706	GGDEF domain
M1S33_00685	COG1393	Belongs to the ArsC family
M1S33_00690	COG0708	Exodeoxyribonuclease III
M1S33_00710	COG0189	ligase activity
M1S33_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1S33_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1S33_00755	COG4942	peptidase
M1S33_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1S33_00775	COG2119	membrane
M1S33_00780	COG4774	siderophore transport
M1S33_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S33_00785	COG0426	domain, Protein
M1S33_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1S33_00830	COG1902	pentaerythritol trinitrate reductase activity
M1S33_00835	COG1519	Transferase
M1S33_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1S33_00845	COG0668	transmembrane transport
M1S33_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S33_00860	COG1335	isochorismatase
M1S33_00865	COG1522	sequence-specific DNA binding
M1S33_00870	COG3328	transposase activity
M1S33_00895	COG0784	Response regulator, receiver
M1S33_00895	COG2198	Histidine kinase
M1S33_00895	COG2205	protein histidine kinase activity
M1S33_00900	COG3162	membrane
M1S33_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1S33_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S33_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1S33_00940	COG1309	transcriptional regulator
M1S33_00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1S33_00960	COG0352	thiamine-phosphate diphosphorylase activity
M1S33_00960	COG0351	phosphomethylpyrimidine kinase
M1S33_00970	COG2814	Major facilitator Superfamily
M1S33_00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1S33_00995	COG1113	amino acid transport
M1S33_01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1S33_01010	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_01020	COG1335	isochorismatase
M1S33_01050	COG2814	Major facilitator Superfamily
M1S33_01055	COG0583	DNA-binding transcription factor activity
M1S33_01075	COG0667	Aldo Keto reductase
M1S33_01110	COG1733	regulation of RNA biosynthetic process
M1S33_01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S33_01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1S33_01195	COG2329	Antibiotic biosynthesis monooxygenase
M1S33_01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M1S33_01255	COG0427	acetyl-CoA hydrolase
M1S33_01280	COG0659	secondary active sulfate transmembrane transporter activity
M1S33_01285	COG4221	oxidoreductase activity
M1S33_01290	COG2873	o-acetylhomoserine
M1S33_01295	COG0488	(ABC) transporter
M1S33_01380	COG0833	amino acid
M1S33_01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1S33_01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1S33_01445	COG2226	methyltransferase
M1S33_01495	COG0067	glutamate synthase
M1S33_01495	COG0069	glutamate synthase activity
M1S33_01495	COG0070	glutamate synthase
M1S33_01500	COG0493	'glutamate synthase
M1S33_01510	COG1704	LemA family
M1S33_01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M1S33_01535	COG3307	-O-antigen
M1S33_01555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1S33_01570	COG0194	GDP metabolic process
M1S33_01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M1S33_01640	COG5380	lipid catabolic process
M1S33_01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M1S33_01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1S33_01675	COG0277	FAD linked oxidase domain protein
M1S33_01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M1S33_01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S33_01705	COG1289	transmembrane transporter activity
M1S33_01715	COG0628	permease
M1S33_01720	COG1192	Involved in chromosome partitioning
M1S33_01750	COG0833	amino acid
M1S33_01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1S33_01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1S33_01770	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_01810	COG0583	DNA-binding transcription factor activity
M1S33_01855	COG0517	IMP dehydrogenase activity
M1S33_01860	COG1983	PspC domain protein
M1S33_01870	COG1960	acyl-CoA dehydrogenase activity
M1S33_01885	COG0408	coproporphyrinogen oxidase activity
M1S33_01905	COG0513	Belongs to the DEAD box helicase family
M1S33_01915	COG1127	ABC transporter
M1S33_01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M1S33_01930	COG2854	intermembrane phospholipid transfer
M1S33_01940	COG0598	Magnesium transport protein CorA
M1S33_01950	COG0494	nUDIX hydrolase
M1S33_01955	COG1040	competence protein
M1S33_01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1S33_01980	COG1946	Acyl-CoA thioesterase
M1S33_01985	COG1301	dicarboxylic acid transport
M1S33_02000	COG1959	2 iron, 2 sulfur cluster binding
M1S33_02005	COG1017	nitric oxide dioxygenase activity
M1S33_02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S33_02010	COG0433	COG0433 Predicted ATPase
M1S33_02015	COG0626	cystathionine gamma-synthase activity
M1S33_02170	COG1960	acyl-CoA dehydrogenase activity
M1S33_02175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M1S33_02205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M1S33_02210	COG0339	signal peptide processing
M1S33_02215	COG0557	exoribonuclease II activity
M1S33_02260	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1S33_02265	COG2169	Transcriptional regulator
M1S33_02270	COG0697	spore germination
M1S33_02275	COG1295	ribonuclease BN
M1S33_02310	COG1702	phosphate starvation-inducible protein PhoH
M1S33_02320	COG0741	lytic transglycosylase activity
M1S33_02320	COG1196	nuclear chromosome segregation
M1S33_02320	COG0739	heme binding
M1S33_02350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M1S33_02355	COG1183	phosphatidylcholine synthase activity
M1S33_02400	COG1960	acyl-CoA dehydrogenase activity
M1S33_02405	COG1309	transcriptional regulator
M1S33_02420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1S33_02425	COG1960	acyl-CoA dehydrogenase activity
M1S33_02445	COG2969	positive regulation of protein catabolic process
M1S33_02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M1S33_02470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M1S33_02475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M1S33_02495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1S33_02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1S33_02510	COG1408	metallophosphoesterase
M1S33_02520	COG2199	diguanylate cyclase activity
M1S33_02580	COG1607	acyl-coa hydrolase
M1S33_02610	COG2350	Protein conserved in bacteria
M1S33_02620	COG0613	PHP domain protein
M1S33_02625	COG3781	membrane
M1S33_02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1S33_02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1S33_02650	COG1862	Preprotein translocase
M1S33_02680	COG2205	protein histidine kinase activity
M1S33_02685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M1S33_02705	COG0726	polysaccharide deacetylase
M1S33_02710	COG0463	Glycosyl transferase, family 2
M1S33_02715	COG0438	transferase activity, transferring glycosyl groups
M1S33_02780	COG0625	glutathione transferase activity
M1S33_02785	COG0583	DNA-binding transcription factor activity
M1S33_02790	COG1960	acyl-CoA dehydrogenase activity
M1S33_02795	COG1960	acyl-CoA dehydrogenase activity
M1S33_02805	COG2205	protein histidine kinase activity
M1S33_02810	COG0745	RESPONSE REGULATOR receiver
M1S33_02815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M1S33_02835	COG2096	Adenosyltransferase
M1S33_02885	COG0285	dihydrofolate synthase activity
M1S33_02905	COG0450	alkyl hydroperoxide reductase
M1S33_02920	COG0477	Major facilitator Superfamily
M1S33_02925	COG1272	protein, Hemolysin III
M1S33_02955	COG0183	Belongs to the thiolase family
M1S33_02960	COG2207	Transcriptional regulator
M1S33_02980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S33_03000	COG0183	Belongs to the thiolase family
M1S33_03010	COG2885	chlorophyll binding
M1S33_03010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M1S33_03020	COG1690	Belongs to the RtcB family
M1S33_03025	COG0833	amino acid
M1S33_03035	COG2233	PERMEase
M1S33_03040	COG1217	gtp-binding protein TYPA
M1S33_03065	COG2094	Belongs to the DNA glycosylase MPG family
M1S33_03085	COG1902	pentaerythritol trinitrate reductase activity
M1S33_03100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S33_03105	COG0354	folic acid binding
M1S33_03115	COG3189	MarR family transcriptional regulator
M1S33_03120	COG2824	Alkylphosphonate utilization operon protein PhnA
M1S33_03165	COG0840	transmembrane signaling receptor activity
M1S33_03185	COG5510	response to toxic substance
M1S33_03195	COG2832	Protein of unknown function (DUF454)
M1S33_03200	COG1376	ErfK ybiS ycfS ynhG family protein
M1S33_03240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M1S33_03250	COG1289	transmembrane transporter activity
M1S33_03255	COG2814	Major facilitator Superfamily
M1S33_03275	COG1115	amino acid carrier protein
M1S33_03280	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1S33_03285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1S33_03290	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
M1S33_03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1S33_03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1S33_03345	COG1077	Cell shape determining protein MreB Mrl
M1S33_03350	COG1792	Involved in formation and maintenance of cell shape
M1S33_03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M1S33_03360	COG0424	maF-like protein
M1S33_03365	COG1530	ribonuclease E activity
M1S33_03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S33_03385	COG0560	Phosphoserine phosphatase
M1S33_03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S33_03420	COG2207	Transcriptional regulator
M1S33_03440	COG1113	amino acid transport
M1S33_03445	COG2828	Protein conserved in bacteria
M1S33_03450	COG0142	geranyltranstransferase activity
M1S33_03455	COG2315	Protein conserved in bacteria
M1S33_03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1S33_03490	COG2194	sulfuric ester hydrolase activity
M1S33_03495	COG0745	RESPONSE REGULATOR receiver
M1S33_03500	COG0642	Histidine kinase
M1S33_03510	COG0004	ammonium transporteR
M1S33_03515	COG0583	DNA-binding transcription factor activity
M1S33_03535	COG0525	valine-tRNA ligase activity
M1S33_03545	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_03555	COG0393	Putative heavy-metal-binding
M1S33_03560	COG0393	Putative heavy-metal-binding
M1S33_03565	COG1538	Outer membrane efflux protein
M1S33_03575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S33_03580	COG0671	phosphoesterase, PA-phosphatase related
M1S33_03610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1S33_03625	COG1648	precorrin-2 dehydrogenase activity
M1S33_03625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1S33_03630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1S33_03635	COG1733	regulation of RNA biosynthetic process
M1S33_03645	COG0531	amino acid
M1S33_03660	COG0321	lipoyl(octanoyl) transferase activity
M1S33_03665	COG2921	Belongs to the UPF0250 family
M1S33_03705	COG2009	succinate dehydrogenase
M1S33_03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M1S33_03715	COG1053	succinate dehydrogenase
M1S33_03720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1S33_03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S33_03765	COG2354	Protein conserved in bacteria
M1S33_03770	COG2321	neutral zinc metallopeptidase
M1S33_03790	COG2843	Capsule synthesis protein
M1S33_03805	COG0589	response to stress
M1S33_03825	COG0505	Belongs to the CarA family
M1S33_03850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1S33_03855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1S33_03905	COG0477	Major facilitator Superfamily
M1S33_03910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M1S33_03925	COG1597	lipid kinase activity
M1S33_03930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1S33_03960	COG0584	glycerophosphoryl diester phosphodiesterase
M1S33_03980	COG0741	lytic transglycosylase activity
M1S33_04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M1S33_04015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S33_04045	COG0778	Nitroreductase
M1S33_04060	COG1929	Belongs to the glycerate kinase type-1 family
M1S33_04065	COG0243	molybdopterin cofactor binding
M1S33_04070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1S33_04075	COG3339	Conserved Protein
M1S33_04085	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
M1S33_04100	COG1113	amino acid transport
M1S33_04110	COG0019	diaminopimelate decarboxylase activity
M1S33_04120	COG1280	lysine exporter protein (LysE YggA)
M1S33_04125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1S33_04155	COG0463	Glycosyl transferase, family 2
M1S33_04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S33_04210	COG4591	ABC-type transport system involved in lipoprotein release permease component
M1S33_04215	COG1136	(ABC) transporter
M1S33_04220	COG2333	competence protein COMEC
M1S33_04220	COG0658	competence protein
M1S33_04230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M1S33_04230	COG0616	signal peptide processing
M1S33_04235	COG0596	Alpha beta hydrolase
M1S33_04240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1S33_04250	COG0628	permease
M1S33_04285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1S33_04305	COG0823	Involved in the tonB-independent uptake of proteins
M1S33_04325	COG0824	Thioesterase
M1S33_04330	COG1473	amidohydrolase
M1S33_04350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1S33_04350	COG0047	phosphoribosylformylglycinamidine synthase activity
M1S33_04355	COG2814	Major facilitator Superfamily
M1S33_04365	COG1024	Enoyl-CoA hydratase
M1S33_04370	COG1056	cytidyltransferase-related domain
M1S33_04370	COG1051	belongs to the nudix hydrolase family
M1S33_04380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1S33_04395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M1S33_04410	COG4625	pathogenesis
M1S33_04415	COG0583	DNA-binding transcription factor activity
M1S33_04420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M1S33_04425	COG4208	sulfate ABC transporter
M1S33_04430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M1S33_04440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M1S33_04445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1S33_04450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1S33_04470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1S33_04485	COG0681	Belongs to the peptidase S26 family
M1S33_04500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1S33_04510	COG1381	Involved in DNA repair and RecF pathway recombination
M1S33_04515	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M1S33_04525	COG4221	oxidoreductase activity
M1S33_04555	COG0436	Aminotransferase
M1S33_04575	COG0556	nucleotide-excision repair
M1S33_04630	COG2070	2-Nitropropane dioxygenase
M1S33_04660	COG1215	transferase activity, transferring glycosyl groups
M1S33_04675	COG0415	Belongs to the DNA photolyase family
M1S33_04685	COG1252	NADH dehydrogenase
M1S33_04690	COG1686	Belongs to the peptidase S11 family
M1S33_04705	COG1187	pseudouridine synthase activity
M1S33_04730	COG0477	Major facilitator Superfamily
M1S33_04735	COG0583	DNA-binding transcription factor activity
M1S33_04740	COG1823	symporter activity
M1S33_04750	COG0612	Peptidase, M16
M1S33_04775	COG0352	thiamine-phosphate diphosphorylase activity
M1S33_04810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S33_04825	COG1309	transcriptional regulator
M1S33_04835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1S33_04840	COG0076	glutamate decarboxylase activity
M1S33_04850	COG1522	sequence-specific DNA binding
M1S33_04855	COG3961	Belongs to the TPP enzyme family
M1S33_04860	COG1113	amino acid transport
M1S33_04865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1S33_04870	COG0573	inorganic phosphate transmembrane transporter activity
M1S33_04880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M1S33_04885	COG0616	signal peptide processing
M1S33_04895	COG3328	transposase activity
M1S33_04925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1S33_04930	COG1686	Belongs to the peptidase S11 family
M1S33_04955	COG0583	DNA-binding transcription factor activity
M1S33_04960	COG1067	ATP-dependent peptidase activity
M1S33_05005	COG1966	Carbon starvation protein
M1S33_05010	COG2879	small protein
M1S33_05045	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M1S33_05045	COG2508	Transcriptional regulator
M1S33_05065	COG1113	amino acid transport
M1S33_05070	COG0583	DNA-binding transcription factor activity
M1S33_05075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S33_05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S33_05090	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_05100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S33_05105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S33_05105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
M1S33_05140	COG2814	Major facilitator Superfamily
M1S33_05145	COG4948	Mandelate Racemase Muconate Lactonizing
M1S33_05155	COG1309	transcriptional regulator
M1S33_05175	COG1741	Belongs to the pirin family
M1S33_05185	COG2964	Protein conserved in bacteria
M1S33_05200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S33_05205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1S33_05210	COG4605	iron ion homeostasis
M1S33_05215	COG4604	ABC transporter, ATP-binding protein
M1S33_05220	COG4607	ABC-type enterochelin transport system periplasmic component
M1S33_05225	COG4774	siderophore transport
M1S33_05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1S33_05240	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1S33_05245	COG3433	isochorismatase activity
M1S33_05245	COG1535	isochorismatase
M1S33_05260	COG1132	(ABC) transporter
M1S33_05265	COG1132	(ABC) transporter
M1S33_05270	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M1S33_05280	COG1169	isochorismate synthase
M1S33_05295	COG3739	integral membrane protein
M1S33_05320	COG0302	gtp cyclohydrolase
M1S33_05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M1S33_05360	COG0308	aminopeptidase N
M1S33_05365	COG0512	Glutamine amidotransferase of anthranilate synthase
M1S33_05380	COG0174	glutamine synthetase
M1S33_05390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
M1S33_05425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1S33_05430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1S33_05435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1S33_05455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1S33_05460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1S33_05465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
M1S33_05480	COG1960	acyl-CoA dehydrogenase activity
M1S33_05485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1S33_05490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S33_05500	COG2223	nitrite transmembrane transporter activity
M1S33_05510	COG0024	Methionine aminopeptidase
M1S33_05515	COG0052	Belongs to the universal ribosomal protein uS2 family
M1S33_05530	COG2207	Transcriptional regulator
M1S33_05555	COG2951	lytic endotransglycosylase activity
M1S33_05560	COG0772	Belongs to the SEDS family
M1S33_05575	COG0842	Transport permease protein
M1S33_05580	COG1131	(ABC) transporter
M1S33_05625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S33_05640	COG4215	(ABC) transporter
M1S33_05645	COG4160	amino acid transport
M1S33_05650	COG4598	ABC transporter
M1S33_05660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1S33_05665	COG0826	peptidase U32
M1S33_05670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S33_05685	COG1720	tRNA m6t6A37 methyltransferase activity
M1S33_05695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1S33_05710	COG0642	Histidine kinase
M1S33_05720	COG0494	nUDIX hydrolase
M1S33_05730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1S33_05735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M1S33_05740	COG3139	Protein of unknown function (DUF1315)
M1S33_05745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M1S33_05750	COG1301	dicarboxylic acid transport
M1S33_05755	COG1960	acyl-CoA dehydrogenase activity
M1S33_05760	COG2819	hydrolase of the alpha beta superfamily
M1S33_05770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M1S33_05780	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1S33_05785	COG1234	tRNA 3'-trailer cleavage
M1S33_05815	COG2363	Small membrane protein
M1S33_05840	COG0513	Belongs to the DEAD box helicase family
M1S33_05850	COG0778	Nitroreductase
M1S33_06200	COG1286	toxin biosynthetic process
M1S33_06225	COG4783	chaperone-mediated protein folding
M1S33_06230	COG1610	YqeY-like protein
M1S33_06330	COG3111	PFAM Bacterial OB fold (BOF) protein
M1S33_06355	COG3243	poly(R)-hydroxyalkanoic acid synthase
M1S33_06360	COG0786	glutamate:sodium symporter activity
M1S33_06370	COG2186	Transcriptional regulator
M1S33_06420	COG0477	Major facilitator Superfamily
M1S33_06450	COG2985	domain, Protein
M1S33_06460	COG2995	paraquat-inducible protein a
M1S33_06465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M1S33_06465	COG3008	intermembrane lipid transfer
M1S33_06495	COG0488	(ABC) transporter
M1S33_06500	COG3173	Aminoglycoside phosphotransferase
M1S33_06510	COG2433	Pfam Transposase IS66
M1S33_06550	COG1301	dicarboxylic acid transport
M1S33_06560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S33_06565	COG2011	ABC-type metal ion transport system permease component
M1S33_06570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1S33_06575	COG1464	Belongs to the NlpA lipoprotein family
M1S33_06580	COG0151	Belongs to the GarS family
M1S33_06585	COG0138	bifunctional purine biosynthesis protein purh
M1S33_06590	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M1S33_06620	COG2308	Evidence 4 Homologs of previously reported genes of
M1S33_06630	COG1305	Transglutaminase-like
M1S33_06640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1S33_06645	COG0305	Participates in initiation and elongation during chromosome replication
M1S33_06670	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M1S33_06680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1S33_06685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1S33_06710	COG0726	polysaccharide deacetylase
M1S33_06710	COG1649	PFAM Uncharacterised BCR, COG1649
M1S33_06715	COG1215	transferase activity, transferring glycosyl groups
M1S33_06720	COG3658	cytochrome
M1S33_06730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S33_06745	COG0583	DNA-binding transcription factor activity
M1S33_06765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S33_06770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S33_06785	COG1960	acyl-CoA dehydrogenase activity
M1S33_06790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S33_06795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S33_06820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M1S33_06825	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M1S33_06835	COG2205	protein histidine kinase activity
M1S33_06840	COG0745	RESPONSE REGULATOR receiver
M1S33_06845	COG0174	glutamine synthetase
M1S33_06875	COG0729	surface antigen
M1S33_06900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1S33_06905	COG2814	Major facilitator Superfamily
M1S33_06920	COG0583	DNA-binding transcription factor activity
M1S33_06935	COG1187	pseudouridine synthase activity
M1S33_06955	COG0802	atpase or kinase
M1S33_06960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M1S33_06970	COG1923	regulation of RNA biosynthetic process
M1S33_06975	COG0697	spore germination
M1S33_06990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S33_07000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1S33_07005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1S33_07005	COG0519	Catalyzes the synthesis of GMP from XMP
M1S33_07010	COG4302	ethanolamine ammonia-lyase activity
M1S33_07015	COG4303	Ethanolamine ammonia lyase large subunit
M1S33_07020	COG0531	amino acid
M1S33_07040	COG1454	alcohol dehydrogenase
M1S33_07045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1S33_07055	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M1S33_07075	COG0308	aminopeptidase N
M1S33_07105	COG1605	Chorismate mutase
M1S33_07125	COG1309	transcriptional regulator
M1S33_07135	COG0668	transmembrane transport
M1S33_07170	COG4773	Receptor
M1S33_07190	COG0488	(ABC) transporter
M1S33_07195	COG0589	response to stress
M1S33_07220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1S33_07230	COG3135	benzoate transporter
M1S33_07235	COG1522	sequence-specific DNA binding
M1S33_07245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M1S33_07250	COG0583	DNA-binding transcription factor activity
M1S33_07260	COG0183	Belongs to the thiolase family
M1S33_07270	COG2030	dehydratase
M1S33_07275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1S33_07290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1S33_07300	COG0824	Thioesterase
M1S33_07305	COG1454	alcohol dehydrogenase
M1S33_07315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1S33_07335	COG0069	glutamate synthase activity
M1S33_07500	COG5410	chromosome segregation
M1S33_07620	COG0739	heme binding
M1S33_07685	COG2814	Major facilitator Superfamily
M1S33_07700	COG0511	ligase activity, forming carbon-carbon bonds
M1S33_07720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S33_07720	COG1116	anion transmembrane transporter activity
M1S33_07725	COG0745	RESPONSE REGULATOR receiver
M1S33_07735	COG2146	nitrite reductase [NAD(P)H] activity
M1S33_07735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S33_07740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S33_07745	COG0243	molybdopterin cofactor binding
M1S33_07755	COG0243	molybdopterin cofactor binding
M1S33_07760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M1S33_07775	COG0315	cyclic pyranopterin monophosphate synthase activity
M1S33_07775	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1S33_07780	COG0303	'Molybdopterin
M1S33_07790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S33_07795	COG0697	spore germination
M1S33_07815	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M1S33_07820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1S33_07875	COG2204	response regulator
M1S33_07880	COG3852	Histidine kinase
M1S33_07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1S33_07905	COG0575	Belongs to the CDS family
M1S33_07940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S33_07955	COG2137	regulation of response to DNA damage stimulus
M1S33_07965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1S33_07970	COG1011	Hydrolase
M1S33_07995	COG1522	sequence-specific DNA binding
M1S33_08005	COG1113	amino acid transport
M1S33_08025	COG0659	secondary active sulfate transmembrane transporter activity
M1S33_08030	COG2135	peptidase activity
M1S33_08045	COG5001	Diguanylate cyclase
M1S33_08045	COG3300	MHYT domain
M1S33_08065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1S33_08065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M1S33_08065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1S33_08070	COG1105	Belongs to the carbohydrate kinase PfkB family
M1S33_08075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1S33_08075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M1S33_08105	COG0024	Methionine aminopeptidase
M1S33_08110	COG0583	DNA-binding transcription factor activity
M1S33_08120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M1S33_08125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1S33_08130	COG0516	GMP reductase activity
M1S33_08130	COG0517	IMP dehydrogenase activity
M1S33_08155	COG0552	protein localization to endoplasmic reticulum
M1S33_08165	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M1S33_08180	COG4890	Cyd operon protein YbgT
M1S33_08185	COG1294	oxidase, subunit
M1S33_08200	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1S33_08210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1S33_08215	COG4774	siderophore transport
M1S33_08230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1S33_08235	COG0569	domain protein
M1S33_08240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1S33_08270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M1S33_08275	COG0542	response to heat
M1S33_08300	COG1902	pentaerythritol trinitrate reductase activity
M1S33_08300	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S33_08345	COG2323	membrane
M1S33_08350	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M1S33_08360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S33_08365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S33_08370	COG0183	Belongs to the thiolase family
M1S33_08375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1S33_08380	COG0596	Alpha beta hydrolase
M1S33_08385	COG2271	Major facilitator Superfamily
M1S33_08390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1S33_08395	COG3485	protocatechuate 3,4-dioxygenase
M1S33_08400	COG3485	protocatechuate 3,4-dioxygenase
M1S33_08405	COG0710	3-dehydroquinate dehydratase activity
M1S33_08410	COG3420	alginic acid biosynthetic process
M1S33_08415	COG3659	wide pore channel activity
M1S33_08420	COG4993	Dehydrogenase
M1S33_08430	COG2391	methyltransferase activity
M1S33_08445	COG1414	Transcriptional regulator
M1S33_08450	COG0583	DNA-binding transcription factor activity
M1S33_08455	COG1960	acyl-CoA dehydrogenase activity
M1S33_08480	COG2814	Major facilitator Superfamily
M1S33_08490	COG0154	amidase activity
M1S33_08510	COG4638	Rieske (2fe-2S)
M1S33_08520	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_08530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S33_08540	COG3733	amine oxidase
M1S33_08550	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_08560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S33_08565	COG0183	Belongs to the thiolase family
M1S33_08570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S33_08575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S33_08585	COG4829	muconolactone delta-isomerase
M1S33_08590	COG4948	Mandelate Racemase Muconate Lactonizing
M1S33_08595	COG0583	DNA-binding transcription factor activity
M1S33_08605	COG2186	Transcriptional regulator
M1S33_08625	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_08645	COG1960	acyl-CoA dehydrogenase activity
M1S33_08650	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_08655	COG3829	transcription factor binding
M1S33_08665	COG3162	membrane
M1S33_08680	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_08695	COG0753	catalase activity
M1S33_08715	COG1846	Transcriptional regulator
M1S33_08720	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S33_08720	COG1902	pentaerythritol trinitrate reductase activity
M1S33_08730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1S33_08760	COG1309	transcriptional regulator
M1S33_08770	COG1335	isochorismatase
M1S33_08775	COG0583	DNA-binding transcription factor activity
M1S33_08785	COG0475	glutathione-regulated potassium exporter activity
M1S33_08785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S33_08795	COG1473	amidohydrolase
M1S33_08805	COG2831	hemolysin activation secretion protein
M1S33_08810	COG3210	domain, Protein
M1S33_08840	COG2188	Transcriptional regulator
M1S33_08855	COG0583	DNA-binding transcription factor activity
M1S33_08885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1S33_08915	COG1566	PFAM secretion protein HlyD family protein
M1S33_08930	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_08935	COG0129	dihydroxy-acid dehydratase activity
M1S33_08945	COG0583	DNA-binding transcription factor activity
M1S33_08950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1S33_08960	COG2084	Dehydrogenase
M1S33_08965	COG2207	Transcriptional regulator
M1S33_08980	COG1064	alcohol dehydrogenase
M1S33_08990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1S33_08995	COG1120	ATPase activity
M1S33_09015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1S33_09135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
M1S33_09185	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_09200	COG2207	Transcriptional regulator
M1S33_09210	COG2205	protein histidine kinase activity
M1S33_09215	COG0745	RESPONSE REGULATOR receiver
M1S33_09220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S33_09225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1S33_09230	COG1538	Outer membrane efflux protein
M1S33_09240	COG2072	flavoprotein involved in K transport
M1S33_09260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S33_09280	COG3539	Fimbrial protein
M1S33_09310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
M1S33_09320	COG0753	catalase activity
M1S33_09335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1S33_09400	COG1535	isochorismatase
M1S33_09400	COG3433	isochorismatase activity
M1S33_09405	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_09410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
M1S33_09415	COG4149	molybdate abc transporter
M1S33_09420	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1S33_09430	COG4638	Rieske (2fe-2S)
M1S33_09435	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1S33_09440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S33_09440	COG0543	2 iron, 2 sulfur cluster binding
M1S33_09465	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_09480	COG2207	Transcriptional regulator
M1S33_09490	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_09495	COG2610	gluconate transmembrane transporter activity
M1S33_09505	COG0583	DNA-binding transcription factor activity
M1S33_09515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S33_09520	COG2031	fatty acid transporter
M1S33_09525	COG0183	Belongs to the thiolase family
M1S33_09530	COG0583	DNA-binding transcription factor activity
M1S33_09535	COG0583	DNA-binding transcription factor activity
M1S33_09550	COG1027	Aspartate ammonia-lyase
M1S33_09560	COG0477	Major facilitator Superfamily
M1S33_09580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S33_09585	COG4521	taurine ABC transporter
M1S33_09600	COG2188	Transcriptional regulator
M1S33_09610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1S33_09615	COG1733	regulation of RNA biosynthetic process
M1S33_09620	COG3708	Transcriptional regulator
M1S33_09620	COG2207	Transcriptional regulator
M1S33_09635	COG0730	response to heat
M1S33_09650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S33_09650	COG3453	Protein conserved in bacteria
M1S33_09660	COG3781	membrane
M1S33_09665	COG1063	alcohol dehydrogenase
M1S33_09675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1S33_09680	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1S33_09685	COG0022	dehydrogenase e1 component
M1S33_09690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1S33_09695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1S33_09710	COG3706	GGDEF domain
M1S33_09725	COG0133	tryptophan synthase activity
M1S33_09735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1S33_09770	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M1S33_09795	COG2226	methyltransferase
M1S33_09850	COG0842	Transport permease protein
M1S33_09855	COG0842	Transport permease protein
M1S33_09860	COG1131	(ABC) transporter
M1S33_09875	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1S33_09880	COG4773	Receptor
M1S33_09900	COG0730	response to heat
M1S33_09905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M1S33_09925	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
M1S33_09940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1S33_09980	COG4264	IucA IucC family
M1S33_09985	COG4264	IucA IucC family
M1S33_10005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1S33_10020	COG1960	acyl-CoA dehydrogenase activity
M1S33_10025	COG1960	acyl-CoA dehydrogenase activity
M1S33_10030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1S33_10035	COG2207	Transcriptional regulator
M1S33_10040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1S33_10045	COG0776	regulation of translation
M1S33_10070	COG0822	iron-sulfur transferase activity
M1S33_10075	COG0316	Belongs to the HesB IscA family
M1S33_10105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1S33_10125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1S33_10130	COG0702	epimerase
M1S33_10165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1S33_10175	COG0339	signal peptide processing
M1S33_10225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M1S33_10230	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M1S33_10260	COG0776	regulation of translation
M1S33_10325	COG0084	hydrolase, TatD family'
M1S33_10345	COG1663	tetraacyldisaccharide 4'-kinase activity
M1S33_10350	COG1132	(ABC) transporter
M1S33_10360	COG0811	peptide transport
M1S33_10365	COG1475	DNA binding
M1S33_10370	COG1192	Involved in chromosome partitioning
M1S33_10380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1S33_10395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1S33_10400	COG0191	fructose-bisphosphate aldolase activity
M1S33_10420	COG0424	maF-like protein
M1S33_10425	COG2850	peptidyl-arginine hydroxylation
M1S33_10435	COG0640	Transcriptional regulator
M1S33_10450	COG3619	membrane
M1S33_10455	COG3122	Protein conserved in bacteria
M1S33_10460	COG1132	(ABC) transporter
M1S33_10480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1S33_10485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1S33_10495	COG0506	proline dehydrogenase activity
M1S33_10495	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M1S33_10495	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M1S33_10500	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1S33_10515	COG3698	Phosphodiester glycosidase
M1S33_10525	COG2353	YceI-like domain
M1S33_10535	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M1S33_10580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M1S33_10580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M1S33_10605	COG3539	Fimbrial protein
M1S33_10610	COG3121	Chaperone
M1S33_10635	COG0697	spore germination
M1S33_10645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1S33_10655	COG0583	DNA-binding transcription factor activity
M1S33_10675	COG1309	transcriptional regulator
M1S33_10690	COG1522	sequence-specific DNA binding
M1S33_10700	COG1126	abc transporter atp-binding protein
M1S33_10705	COG0765	amino acid transport
M1S33_10710	COG0765	amino acid transport
M1S33_10740	COG1464	Belongs to the NlpA lipoprotein family
M1S33_10750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1S33_10755	COG2011	ABC-type metal ion transport system permease component
M1S33_10760	COG0012	GTP binding
M1S33_10785	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1S33_10825	COG0386	Belongs to the glutathione peroxidase family
M1S33_10835	COG0436	Aminotransferase
M1S33_10890	COG0583	DNA-binding transcription factor activity
M1S33_10895	COG0798	PFAM Bile acid sodium symporter
M1S33_10900	COG0640	Transcriptional regulator
M1S33_10915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1S33_10925	COG0583	DNA-binding transcription factor activity
M1S33_10935	COG1953	Uracil, thiamine, allantoin
M1S33_10945	COG2175	clavaminate synthase activity
M1S33_10950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S33_10955	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
M1S33_10960	COG4521	taurine ABC transporter
M1S33_10970	COG0477	Major facilitator Superfamily
M1S33_10990	COG1271	oxidase subunit
M1S33_10995	COG1294	oxidase, subunit
M1S33_11005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1S33_11025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1S33_11045	COG3052	prosthetic group binding
M1S33_11050	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
M1S33_11060	COG2814	Major facilitator Superfamily
M1S33_11080	COG1346	cytolysis
M1S33_11090	COG0583	DNA-binding transcription factor activity
M1S33_11095	COG0625	glutathione transferase activity
M1S33_11100	COG0625	glutathione transferase activity
M1S33_11105	COG0583	DNA-binding transcription factor activity
M1S33_11120	COG1045	serine acetyltransferase
M1S33_11125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1S33_11130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1S33_11140	COG1280	lysine exporter protein (LysE YggA)
M1S33_11155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S33_11160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S33_11165	COG1126	abc transporter atp-binding protein
M1S33_11170	COG0765	amino acid transport
M1S33_11175	COG0765	amino acid transport
M1S33_11195	COG2205	protein histidine kinase activity
M1S33_11195	COG0784	Response regulator, receiver
M1S33_11215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M1S33_11235	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_11285	COG0583	DNA-binding transcription factor activity
M1S33_11305	COG0318	PFAM AMP-dependent synthetase and ligase
M1S33_11310	COG1309	transcriptional regulator
M1S33_11315	COG1960	acyl-CoA dehydrogenase activity
M1S33_11320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1S33_11325	COG1024	Enoyl-CoA hydratase
M1S33_11330	COG4770	biotin carboxylase activity
M1S33_11340	COG0583	DNA-binding transcription factor activity
M1S33_11355	COG1960	acyl-CoA dehydrogenase activity
M1S33_11365	COG2814	Major facilitator Superfamily
M1S33_11375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1S33_11380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1S33_11385	COG2814	Major facilitator Superfamily
M1S33_11390	COG1960	acyl-CoA dehydrogenase activity
M1S33_11395	COG1024	Enoyl-CoA hydratase
M1S33_11400	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_11405	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S33_11410	COG0183	Belongs to the thiolase family
M1S33_11420	COG2814	Major facilitator Superfamily
M1S33_11430	COG1024	Enoyl-CoA hydratase
M1S33_11445	COG1960	acyl-CoA dehydrogenase activity
M1S33_11450	COG2814	Major facilitator Superfamily
M1S33_11460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1S33_11475	COG3842	ATPase activity
M1S33_11480	COG1840	ABC-type Fe3 transport system, periplasmic component
M1S33_11490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S33_11495	COG1414	Transcriptional regulator
M1S33_11505	COG0583	DNA-binding transcription factor activity
M1S33_11510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1S33_11515	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_11525	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1S33_11535	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_11540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S33_11545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S33_11550	COG2267	carboxylic ester hydrolase activity
M1S33_11570	COG3038	cytochrome b561
M1S33_11575	COG0753	catalase activity
M1S33_11610	COG2050	protein possibly involved in aromatic compounds catabolism
M1S33_11620	COG3327	negative regulation of DNA-templated transcription, initiation
M1S33_11625	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
M1S33_11630	COG0183	Belongs to the thiolase family
M1S33_11635	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S33_11640	COG1024	Enoyl-CoA hydratase
M1S33_11645	COG1024	Enoyl-CoA hydratase
M1S33_11650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1S33_11655	COG2151	metal-sulfur cluster biosynthetic enzyme
M1S33_11660	COG3396	Phenylacetate-CoA oxygenase
M1S33_11665	COG3460	Phenylacetate-CoA oxygenase
M1S33_11670	COG3396	Phenylacetate-CoA oxygenase
M1S33_11675	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_11675	COG2030	dehydratase
M1S33_11680	COG1760	l-serine dehydratase
M1S33_11685	COG0531	amino acid
M1S33_11690	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_11705	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S33_11715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1S33_11735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S33_11745	COG0789	Transcriptional regulator
M1S33_11760	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1S33_11775	COG2807	transmembrane transport
M1S33_11780	COG0590	tRNA wobble adenosine to inosine editing
M1S33_11900	COG1116	anion transmembrane transporter activity
M1S33_11905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1S33_11915	COG0864	Transcriptional regulator
M1S33_11935	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1S33_11940	COG0439	Biotin carboxylase
M1S33_11955	COG1063	alcohol dehydrogenase
M1S33_11965	COG1309	transcriptional regulator
M1S33_11985	COG0038	chloride channel
M1S33_11995	COG4770	biotin carboxylase activity
M1S33_12015	COG1914	H( )-stimulated, divalent metal cation uptake system
M1S33_12020	COG0583	DNA-binding transcription factor activity
M1S33_12070	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1S33_12090	COG2814	Major facilitator Superfamily
M1S33_12105	COG1560	Kdo2-lipid A biosynthetic process
M1S33_12115	COG5006	permease, DMT superfamily
M1S33_12120	COG1522	sequence-specific DNA binding
M1S33_12135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
M1S33_12145	COG4122	O-methyltransferase activity
M1S33_12175	COG1538	Outer membrane efflux protein
M1S33_12180	COG1137	ATPase activity
M1S33_12185	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M1S33_12195	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M1S33_12200	COG0517	IMP dehydrogenase activity
M1S33_12200	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M1S33_12235	COG2814	Major facilitator Superfamily
M1S33_12270	COG1278	Cold shock
M1S33_12275	COG1280	lysine exporter protein (LysE YggA)
M1S33_12305	COG1570	exodeoxyribonuclease VII activity
M1S33_12355	COG0583	DNA-binding transcription factor activity
M1S33_12365	COG4638	Rieske (2fe-2S)
M1S33_12370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1S33_12375	COG0633	Ferredoxin
M1S33_12375	COG0543	2 iron, 2 sulfur cluster binding
M1S33_12380	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_12385	COG3135	benzoate transporter
M1S33_12390	COG2814	Major facilitator Superfamily
M1S33_12405	COG1643	Atp-dependent helicase
M1S33_12410	COG0450	alkyl hydroperoxide reductase
M1S33_12420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
M1S33_12430	COG3634	alkyl hydroperoxide reductase activity
M1S33_12450	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M1S33_12455	COG0625	glutathione transferase activity
M1S33_12465	COG2885	chlorophyll binding
M1S33_12500	COG0542	response to heat
M1S33_12515	COG1765	OsmC-like protein
M1S33_12535	COG0667	Aldo Keto reductase
M1S33_12550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M1S33_12560	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1S33_12570	COG0527	aspartate kinase activity
M1S33_12580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M1S33_12590	COG3038	cytochrome b561
M1S33_12595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
M1S33_12600	COG2252	PERMEase
M1S33_12610	COG2072	flavoprotein involved in K transport
M1S33_12625	COG1741	Belongs to the pirin family
M1S33_12630	COG1309	transcriptional regulator
M1S33_12655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1S33_12700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1S33_12745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1S33_12785	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S33_12785	COG1902	pentaerythritol trinitrate reductase activity
M1S33_12795	COG2203	Gaf domain
M1S33_12795	COG3706	GGDEF domain
M1S33_12795	COG4251	negative regulation of phosphorylation
M1S33_12795	COG5001	Diguanylate cyclase
M1S33_12805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S33_12825	COG4172	Belongs to the ABC transporter superfamily
M1S33_12830	COG4239	(ABC) transporter, permease
M1S33_12835	COG4174	ABC transporter (Permease)
M1S33_12845	COG0741	lytic transglycosylase activity
M1S33_12845	COG1388	LysM domain
M1S33_12845	COG0741	lytic transglycosylase activity
M1S33_12845	COG1388	LysM domain
M1S33_12850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S33_12890	COG0583	DNA-binding transcription factor activity
M1S33_12895	COG1279	arginine transmembrane transporter activity
M1S33_12915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S33_12920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S33_12925	COG0006	proline dipeptidase activity
M1S33_12965	COG2194	sulfuric ester hydrolase activity
M1S33_13010	COG0739	heme binding
M1S33_13340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1S33_13365	COG3384	dioxygenase
M1S33_13375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1S33_13380	COG2878	Part of a membrane complex involved in electron transport
M1S33_13385	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1S33_13410	COG0768	penicillin binding
M1S33_13415	COG0742	ribosomal rna small subunit methyltransferase
M1S33_13430	COG0830	nickel cation binding
M1S33_13440	COG0804	urea catabolic process
M1S33_13480	COG1253	flavin adenine dinucleotide binding
M1S33_13485	COG2851	Citrate transporter
M1S33_13540	COG1773	rubredoxin
M1S33_13545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1S33_13555	COG0583	DNA-binding transcription factor activity
M1S33_13580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M1S33_13585	COG4181	ATPase activity
M1S33_13630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
M1S33_13650	COG0306	phosphate transporter
M1S33_13660	COG3958	Transketolase
M1S33_13665	COG3959	Transketolase, thiamine diphosphate binding domain
M1S33_13670	COG2271	Major facilitator Superfamily
M1S33_13675	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_13680	COG0583	DNA-binding transcription factor activity
M1S33_13695	COG2223	nitrite transmembrane transporter activity
M1S33_13700	COG2207	Transcriptional regulator
M1S33_13705	COG2066	Belongs to the glutaminase family
M1S33_13710	COG0242	peptide deformylase activity
M1S33_13715	COG0477	Major facilitator Superfamily
M1S33_13725	COG0028	Belongs to the TPP enzyme family
M1S33_13740	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_13745	COG2267	carboxylic ester hydrolase activity
M1S33_13755	COG2271	Major facilitator Superfamily
M1S33_13760	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1S33_13770	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_13790	COG1414	Transcriptional regulator
M1S33_13805	COG1024	Enoyl-CoA hydratase
M1S33_13815	COG1215	transferase activity, transferring glycosyl groups
M1S33_13820	COG0726	polysaccharide deacetylase
M1S33_13820	COG1649	PFAM Uncharacterised BCR, COG1649
M1S33_13830	COG4681	YaeQ
M1S33_13840	COG0523	cobalamin synthesis protein
M1S33_13850	COG1607	acyl-coa hydrolase
M1S33_13860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S33_13865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1S33_13870	COG1309	transcriptional regulator
M1S33_13895	COG2040	homocysteine
M1S33_13900	COG0531	amino acid
M1S33_13955	COG1595	DNA-templated transcription, initiation
M1S33_13965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S33_13970	COG0477	Major facilitator Superfamily
M1S33_13990	COG0084	hydrolase, TatD family'
M1S33_14025	COG0629	single-stranded DNA binding
M1S33_14080	COG0582	viral genome integration into host DNA
M1S33_14185	COG0592	DNA-directed DNA polymerase activity
M1S33_14225	COG2026	Addiction module toxin, RelE StbE family
M1S33_14415	COG1484	DNA-dependent DNA replication
M1S33_14505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1S33_14575	COG0405	Gamma-glutamyltransferase
M1S33_14580	COG2814	Major facilitator Superfamily
M1S33_14590	COG2050	protein possibly involved in aromatic compounds catabolism
M1S33_14605	COG1090	epimerase
M1S33_14630	COG0420	3'-5' exonuclease activity
M1S33_14655	COG0735	belongs to the Fur family
M1S33_14660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M1S33_14680	COG0121	glutamine amidotransferase
M1S33_14695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S33_14705	COG0210	DNA helicase
M1S33_14710	COG2885	chlorophyll binding
M1S33_14715	COG0204	Acyl-transferase
M1S33_14730	COG2894	cell division
M1S33_14755	COG1280	lysine exporter protein (LysE YggA)
M1S33_14760	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M1S33_14760	COG1674	ftsk spoiiie
M1S33_14765	COG0492	ferredoxin-NADP+ reductase activity
M1S33_14770	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
M1S33_14780	COG0456	acetyltransferase
M1S33_14825	COG1981	membrane
M1S33_14840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M1S33_14840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1S33_14860	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_14870	COG0657	acetylesterase activity
M1S33_14880	COG0473	3-isopropylmalate dehydrogenase activity
M1S33_14885	COG0583	DNA-binding transcription factor activity
M1S33_14905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1S33_14930	COG0564	pseudouridine synthase activity
M1S33_14940	COG0358	DNA primase activity
M1S33_14955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
M1S33_14985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1S33_15015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M1S33_15025	COG0352	thiamine-phosphate diphosphorylase activity
M1S33_15025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1S33_15025	COG0351	phosphomethylpyrimidine kinase
M1S33_15030	COG1652	LysM domain
M1S33_15055	COG1399	metal-binding, possibly nucleic acid-binding protein
M1S33_15060	COG3101	peptidyl-lysine hydroxylation
M1S33_15065	COG0009	L-threonylcarbamoyladenylate synthase
M1S33_15070	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M1S33_15075	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M1S33_15090	COG4106	trans-aconitate 2-methyltransferase activity
M1S33_15105	COG0596	Alpha beta hydrolase
M1S33_15105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S33_15105	COG2226	methyltransferase
M1S33_15110	COG1877	trehalose-phosphatase activity
M1S33_15115	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
M1S33_15120	COG2223	nitrite transmembrane transporter activity
M1S33_15140	COG1196	nuclear chromosome segregation
M1S33_15150	COG0730	response to heat
M1S33_15165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1S33_15175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1S33_15225	COG0489	protein tyrosine kinase activity
M1S33_15235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S33_15235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S33_15265	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M1S33_15270	COG2081	HI0933 family
M1S33_15280	COG0668	transmembrane transport
M1S33_15300	COG0583	DNA-binding transcription factor activity
M1S33_15320	COG1002	Type II restriction enzyme, methylase subunits
M1S33_15325	COG1061	Type III restriction enzyme res subunit
M1S33_15350	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1S33_15355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1S33_15385	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M1S33_15425	COG0745	RESPONSE REGULATOR receiver
M1S33_15445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1S33_15455	COG2205	protein histidine kinase activity
M1S33_15525	COG4993	Dehydrogenase
M1S33_15550	COG0384	phenazine biosynthesis protein PhzF
M1S33_15575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1S33_15590	COG0583	DNA-binding transcription factor activity
M1S33_15620	COG0583	DNA-binding transcription factor activity
M1S33_15635	COG0583	DNA-binding transcription factor activity
M1S33_15640	COG1053	succinate dehydrogenase
M1S33_15650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M1S33_15655	COG2814	Major facilitator Superfamily
M1S33_15660	COG1960	acyl-CoA dehydrogenase activity
M1S33_15665	COG0583	DNA-binding transcription factor activity
M1S33_15670	COG1063	alcohol dehydrogenase
M1S33_15700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M1S33_15705	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1S33_15710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1S33_15725	COG3667	copper resistance
M1S33_15730	COG2132	Multicopper oxidase
M1S33_15740	COG0561	phosphatase activity
M1S33_15745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1S33_15770	COG1214	PFAM Peptidase M22, glycoprotease
M1S33_15825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1S33_15835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1S33_15840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M1S33_15845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M1S33_15905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1S33_15915	COG1846	Transcriptional regulator
M1S33_15920	COG1764	response to oxidative stress
M1S33_15970	COG0037	tRNA processing
M1S33_15980	COG0248	Ppx GppA phosphatase
M1S33_16010	COG0072	phenylalanine-tRNA ligase activity
M1S33_16055	COG1238	metal cluster binding
M1S33_16060	COG0625	glutathione transferase activity
M1S33_16075	COG0318	PFAM AMP-dependent synthetase and ligase
M1S33_16080	COG3028	Belongs to the UPF0307 family
M1S33_16085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1S33_16105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1S33_16110	COG0617	tRNA 3'-terminal CCA addition
M1S33_16115	COG1555	photosystem II stabilization
M1S33_16120	COG3956	TIGRFAM MazG family protein
M1S33_16130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1S33_16150	COG0784	Response regulator, receiver
M1S33_16150	COG2205	protein histidine kinase activity
M1S33_16150	COG5002	protein histidine kinase activity
M1S33_16155	COG1024	Enoyl-CoA hydratase
M1S33_16160	COG2084	Dehydrogenase
M1S33_16165	COG3622	Belongs to the hyi family
M1S33_16180	COG2433	Pfam Transposase IS66
M1S33_16215	COG0697	spore germination
M1S33_16225	COG2814	Major facilitator Superfamily
M1S33_16230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1S33_16240	COG0583	DNA-binding transcription factor activity
M1S33_16250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1S33_16265	COG0084	hydrolase, TatD family'
M1S33_16280	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M1S33_16310	COG0440	acetolactate synthase activity
M1S33_16315	COG0028	Belongs to the TPP enzyme family
M1S33_16340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1S33_16345	COG0577	efflux transmembrane transporter activity
M1S33_16345	COG1136	(ABC) transporter
M1S33_16350	COG1538	Outer membrane efflux protein
M1S33_16365	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M1S33_16370	COG1162	GTPase activity
M1S33_16380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M1S33_16400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1S33_16405	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_16445	COG2986	histidine ammonia-lyase
M1S33_16460	COG0318	PFAM AMP-dependent synthetase and ligase
M1S33_16470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1S33_16515	COG1426	Protein conserved in bacteria
M1S33_16550	COG0793	Belongs to the peptidase S41A family
M1S33_16565	COG2267	carboxylic ester hydrolase activity
M1S33_16575	COG1012	belongs to the aldehyde dehydrogenase family
M1S33_16580	COG3265	gluconokinase activity
M1S33_16590	COG0800	Aldolase
M1S33_16605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M1S33_16610	COG0280	phosphate acetyltransferase
M1S33_16610	COG0857	belongs to the CobB CobQ family
M1S33_16615	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M1S33_16615	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M1S33_16635	COG0740	serine-type endopeptidase activity
M1S33_16645	COG4774	siderophore transport
M1S33_16655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1S33_16665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1S33_16665	COG2813	Specifically methylates the guanine in position
M1S33_16765	COG0788	formyltetrahydrofolate deformylase activity
M1S33_16790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S33_16790	COG4651	solute:proton antiporter activity
M1S33_16810	COG0724	RNA recognition motif
M1S33_16815	COG0210	DNA helicase
M1S33_16840	COG1733	regulation of RNA biosynthetic process
M1S33_16850	COG2900	Belongs to the SlyX family
M1S33_16855	COG0488	(ABC) transporter
M1S33_16860	COG1280	lysine exporter protein (LysE YggA)
M1S33_16865	COG1560	Kdo2-lipid A biosynthetic process
M1S33_16875	COG1301	dicarboxylic acid transport
M1S33_16930	COG0473	3-isopropylmalate dehydrogenase activity
M1S33_16995	COG0583	DNA-binding transcription factor activity
M1S33_17005	COG0625	glutathione transferase activity
M1S33_17010	COG2378	regulation of single-species biofilm formation
M1S33_17015	COG0546	phosphoglycolate phosphatase activity
M1S33_17025	COG1530	ribonuclease E activity
M1S33_17030	COG0318	PFAM AMP-dependent synthetase and ligase
M1S33_17045	COG0583	DNA-binding transcription factor activity
M1S33_17050	COG4221	oxidoreductase activity
M1S33_17055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1S33_17065	COG0534	Mate efflux family protein
M1S33_17080	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
M1S33_17120	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
M1S33_17125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1S33_17140	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1S33_17150	COG0644	oxidoreductase
M1S33_17150	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
M1S33_17155	COG0425	Belongs to the sulfur carrier protein TusA family
M1S33_17160	COG4535	Mg2 and Co2 transporter CorC
M1S33_17170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1S33_17190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1S33_17195	COG0475	glutathione-regulated potassium exporter activity
M1S33_17195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1S33_17200	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M1S33_17210	COG0484	heat shock protein binding
M1S33_17215	COG0789	Transcriptional regulator
M1S33_17220	COG0598	Magnesium transport protein CorA
M1S33_17235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1S33_17240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1S33_17245	COG1074	ATP-dependent DNA helicase activity
M1S33_17250	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M1S33_17270	COG2226	methyltransferase
M1S33_17285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1S33_17290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M1S33_17305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1S33_17305	COG2111	Na H antiporter
M1S33_17310	COG1006	Multisubunit Na H antiporter MnhC subunit
M1S33_17315	COG0651	ATP synthesis coupled electron transport
M1S33_17320	COG1863	multisubunit Na H antiporter MnhE subunit
M1S33_17325	COG2212	antiporter activity
M1S33_17330	COG1320	monovalent cation:proton antiporter activity
M1S33_17345	COG0195	Participates in both transcription termination and antitermination
M1S33_17395	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1S33_17400	COG0237	dephospho-CoA kinase activity
M1S33_17410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1S33_17425	COG0497	DNA recombination
M1S33_17435	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M1S33_17465	COG2169	Transcriptional regulator
M1S33_17465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1S33_17470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1S33_17535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1S33_17550	COG0326	Molecular chaperone. Has ATPase activity
M1S33_17565	COG2056	Na+-H+ antiporter family
M1S33_17570	COG0596	Alpha beta hydrolase
M1S33_17665	COG0546	phosphoglycolate phosphatase activity
M1S33_17670	COG1716	ATPase activity
M1S33_17715	COG0181	hydroxymethylbilane synthase activity
M1S33_17725	COG3275	phosphorelay sensor kinase activity
M1S33_17745	COG1538	Outer membrane efflux protein
M1S33_17750	COG0697	spore germination
M1S33_17775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1S33_17780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1S33_17785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1S33_17790	COG0772	Belongs to the SEDS family
M1S33_17815	COG4974	Belongs to the 'phage' integrase family
M1S33_17820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S33_17830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M1S33_17840	COG2197	response regulator
M1S33_17855	COG0793	Belongs to the peptidase S41A family
M1S33_17860	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M1S33_17865	COG0795	lipopolysaccharide-transporting ATPase activity
M1S33_17905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1S33_17905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1S33_17915	COG0004	ammonium transporteR
M1S33_17920	COG0347	Belongs to the P(II) protein family
M1S33_17995	COG1061	Type III restriction enzyme res subunit
M1S33_18000	COG1002	Type II restriction enzyme, methylase subunits
M1S33_18010	COG0659	secondary active sulfate transmembrane transporter activity
M1S33_18015	COG0589	response to stress
M1S33_18045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S33_18090	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1S33_18135	COG1061	Type III restriction enzyme res subunit
M1S33_18140	COG1002	Type II restriction enzyme, methylase subunits
M1S33_18155	COG0589	response to stress
M1S33_18210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1S33_18230	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M1S33_18245	COG0318	PFAM AMP-dependent synthetase and ligase
M1S33_18255	COG0477	Major facilitator Superfamily
M1S33_18260	COG2860	membrane
M1S33_18270	COG1253	flavin adenine dinucleotide binding
M1S33_18290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1S33_18330	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1S33_18340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1S33_18410	COG0758	DNA mediated transformation
M1S33_18420	COG0697	spore germination
M1S33_18425	COG1309	transcriptional regulator
M1S33_18440	COG0386	Belongs to the glutathione peroxidase family
M1S33_18505	COG1121	(ABC) transporter
M1S33_18510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1S33_18515	COG1280	lysine exporter protein (LysE YggA)
M1S33_18520	COG2837	iron assimilation
M1S33_18530	COG0281	malic enzyme
M1S33_18575	COG0519	Catalyzes the synthesis of GMP from XMP
M1S33_18575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1S33_18580	COG4399	Belongs to the UPF0754 family
M1S33_18585	COG2259	Doxx family
M1S33_18590	COG0586	Pfam SNARE associated Golgi protein
M1S33_18605	COG1192	Involved in chromosome partitioning
M1S33_18615	COG0271	Belongs to the BolA IbaG family
M1S33_18635	COG2267	carboxylic ester hydrolase activity
M1S33_18655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1S33_18655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M1S33_18655	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M1S33_18655	COG3321	synthase
M1S33_18660	COG1960	acyl-CoA dehydrogenase activity
M1S33_18670	COG2197	response regulator
M1S33_18680	COG3916	Acyl-homoserine-lactone synthase
M1S33_18685	COG0477	Major facilitator Superfamily
M1S33_18690	COG1024	Enoyl-CoA hydratase
M1S33_18695	COG1024	Enoyl-CoA hydratase
M1S33_18700	COG1960	acyl-CoA dehydrogenase activity
M1S33_18705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1S33_18725	COG1113	amino acid transport
M1S33_18730	COG1113	amino acid transport
M1S33_18735	COG0251	oxidation-reduction process
M1S33_18775	COG0564	pseudouridine synthase activity
M1S33_18835	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1S33_18850	COG1802	Transcriptional regulator
M1S33_18860	COG1448	Aminotransferase
M1S33_18865	COG0277	FAD linked oxidase domain protein
M1S33_18875	COG2186	Transcriptional regulator
M1S33_18885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1S33_18890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1S33_18905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1S33_18910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1S33_18915	COG1216	Glycosyl transferase, family 2
M1S33_18945	COG2089	acid synthase
M1S33_18960	COG1083	cytidylyl-transferase
M1S33_18965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M1S33_18970	COG1086	Polysaccharide biosynthesis protein
M1S33_18975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M1S33_18980	COG1596	polysaccharide export
M1S33_19005	COG0728	peptidoglycan biosynthetic process
M1S33_19010	COG3023	N-Acetylmuramoyl-L-alanine amidase
M1S33_19070	COG0546	phosphoglycolate phosphatase activity
M1S33_19075	COG1028	Short-chain dehydrogenase reductase Sdr
M1S33_19095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S33_19100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1S33_19105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1S33_19110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1S33_19115	COG1116	anion transmembrane transporter activity
M1S33_19120	COG1309	transcriptional regulator
M1S33_19125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M1S33_19135	COG0196	riboflavin kinase activity
M1S33_19140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1S33_19150	COG1047	Peptidyl-prolyl cis-trans
M1S33_19190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1S33_19195	COG0657	acetylesterase activity
M1S33_19215	COG0583	DNA-binding transcription factor activity
M1S33_19245	COG2951	lytic endotransglycosylase activity
M1S33_19250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1S33_19265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M1S33_19275	COG0671	phosphoesterase, PA-phosphatase related
M1S33_19280	COG0861	Integral membrane protein TerC family
M1S33_19290	COG0754	glutathionylspermidine amidase activity
M1S33_19300	COG0402	S-adenosylhomocysteine deaminase activity
M1S33_19315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1S33_19320	COG1230	cation diffusion facilitator family transporter
M1S33_19335	COG0706	membrane insertase activity