locus-tag class description Aba5845_00030 ENOG4105PNM synthesis protein Aba5845_00045 ENOG41080TK Universal stress protein Aba5845_00060 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain Aba5845_00065 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain Aba5845_00085 ENOG4105HBR Rna-binding protein Aba5845_00095 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) Aba5845_00100 ENOG4105EEI dihydropteroate synthase Aba5845_00150 ENOG4105CSH Transporter Aba5845_00155 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) Aba5845_00160 ENOG4105C6V Glycerol-3-phosphate dehydrogenase Aba5845_00175 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) Aba5845_00195 ENOG41080IJ Diacylglycerol kinase Aba5845_00205 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase Aba5845_00210 ENOG4105BZS acriflavin resistance protein Aba5845_00225 ENOG4105E4C Lytic transglycosylase catalytic Aba5845_00250 ENOG4108RRZ Transcription elongation factor GreB Aba5845_00265 ENOG4105CEY Amp-dependent synthetase and ligase Aba5845_00305 ENOG4105BZW Glycerate kinase Aba5845_00310 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit Aba5845_00315 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) Aba5845_00330 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) Aba5845_00340 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) Aba5845_00345 ENOG4105C85 amino acid Aba5845_00360 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) Aba5845_00370 ENOG4105N14 lysine exporter protein LysE YggA Aba5845_00375 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Aba5845_00380 ENOG4105BZJ Electron transfer flavoprotein Aba5845_00385 ENOG4105C10 Electron transfer flavoprotein Aba5845_00390 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) Aba5845_00425 ENOG4107KET secretion protein, HlyD family Aba5845_00455 ENOG4105D60 lipoprotein releasing system transmembrane protein Aba5845_00460 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) Aba5845_00465 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 Aba5845_00475 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) Aba5845_00480 ENOG4107R6F Alpha Beta Hydrolase Fold protein Aba5845_00485 ENOG4108V3E phosphoribosylglycinamide formyltransferase Aba5845_00495 ENOG4105C02 permease Aba5845_00545 ENOG4105KCK Peptidoglycan-associated lipoprotein Aba5845_00550 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) Aba5845_00560 ENOG4105M8F Biopolymer transport protein exbD tolR Aba5845_00565 ENOG4105E02 MotA TolQ exbB proton channel Aba5845_00570 ENOG4107YD3 Thioesterase Aba5845_00575 ENOG4105CH2 amidohydrolase Aba5845_00595 ENOG4108ETH Formylglycinamide ribotide synthetase Aba5845_00600 ENOG4105C2C drug resistance transporter, Bcr CflA Aba5845_00605 ENOG4105EGD dinuclear metal center protein, YbgI family Aba5845_00610 ENOG4108UKI Enoyl-CoA hydratase Aba5845_00625 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen Aba5845_00640 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) Aba5845_00645 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) Aba5845_00660 ENOG4107R11 Transcriptional regulator Aba5845_00665 ENOG4108IJ6 ABC transporter Aba5845_00675 ENOG4108I5D sulfate abc transporter Aba5845_00685 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein Aba5845_00690 ENOG4105YAZ 4-amino-4-deoxychorismate lyase Aba5845_00695 ENOG4105HHA aminodeoxychorismate lyase Aba5845_00710 ENOG4108IYU L-aspartate oxidase Aba5845_00715 ENOG4105C0H protease Aba5845_00730 ENOG4105C3F Signal peptidase i Aba5845_00745 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) Aba5845_00755 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) Aba5845_00760 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) Aba5845_00765 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase Aba5845_00770 ENOG4105EMU Dehydrogenase Aba5845_00810 ENOG4105BZU Histidine kinase Aba5845_00820 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) Aba5845_00830 ENOG4105DTR rard protein Aba5845_00865 ENOG4107QS8 (LipO)protein Aba5845_00870 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) Aba5845_00875 ENOG4105EA8 2-Nitropropane dioxygenase Aba5845_00905 ENOG4107R8N Glycosyl transferase, family 2 Aba5845_00920 ENOG4105CVP deoxyribo-dipyrimidine photolyase Aba5845_00925 ENOG4108YZY peptidylprolyl cis-trans isomerase Aba5845_00930 ENOG4105CEP NADH dehydrogenase Aba5845_00935 ENOG4105DZ1 carboxypeptidase Aba5845_00945 ENOG4105E9K Isocitrate dehydrogenase Aba5845_00950 ENOG4108R99 pseudouridine synthase Aba5845_00975 ENOG4105CBP Major Facilitator Aba5845_00980 ENOG4105EGI Transcriptional regulator Aba5845_00985 ENOG4108ETY sodium dicarboxylate symporter Aba5845_00990 ENOG4105JAB phenazine biosynthesis protein, phzf family Aba5845_01020 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) Aba5845_01035 ENOG4105D3G Pseudouridine synthase Aba5845_01040 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) Aba5845_01055 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) Aba5845_01080 ENOG4108JPW Aminotransferase Aba5845_01085 ENOG4105DY8 decarboxylase Aba5845_01095 ENOG4105F7P transcriptional regulator AsnC family Aba5845_01100 ENOG4107RA9 decarboxylase Aba5845_01105 ENOG4105C85 amino acid Aba5845_01110 ENOG4105CVA phosphate Aba5845_01115 ENOG4105C8U phosphate abc transporter Aba5845_01125 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) Aba5845_01130 ENOG4105ERU peptidase Aba5845_01145 ENOG4107QTF adenylosuccinate lyase Aba5845_01165 ENOG4108Z0R Transferase Aba5845_01170 ENOG4105DZ1 carboxypeptidase Aba5845_01190 ENOG4108K5P (LipO)protein Aba5845_01195 ENOG4105EJC lysr family transcriptional regulator Aba5845_01200 ENOG4105DAN ATP-dependent protease Aba5845_01215 ENOG4105DHU Bile acid Aba5845_01235 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein Aba5845_01245 ENOG4105D22 carbon starvation protein Aba5845_01250 ENOG4105VCD cytoplasmic protein Aba5845_01285 ENOG4108K8K Transcriptional regulator Aba5845_01300 ENOG4105C26 Dehydrogenase Aba5845_01305 ENOG4105C85 amino acid Aba5845_01310 ENOG4105ETT transcriptional Regulator, LysR family Aba5845_01315 ENOG4105C94 Transporter Aba5845_01320 ENOG4105C94 Transporter Aba5845_01330 ENOG4105C26 Dehydrogenase Aba5845_01335 ENOG4107QZF nitrite reductase NADPH large subunit Aba5845_01340 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) Aba5845_01370 ENOG41060M8 Pfam:PhdYeFM Aba5845_01375 ENOG4107QNK )-transporter Aba5845_01380 ENOG4107WEA mandelate racemase muconate lactonizing Aba5845_01390 ENOG4105J7D transcriptional regulator Aba5845_01410 ENOG4105C2I pirin domain protein Aba5845_01420 ENOG4105WWK YheO domain protein Aba5845_01435 ENOG4105CEY Amp-dependent synthetase and ligase Aba5845_01450 ENOG4108IPW abc transporter atp-binding protein Aba5845_01470 ENOG4105C0W non-ribosomal peptide synthetase Aba5845_01475 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase Aba5845_01480 ENOG4105WQI isochorismatase Aba5845_01495 ENOG4105BZ1 (ABC) transporter Aba5845_01515 ENOG4105E4F Isochorismate synthase Aba5845_01530 ENOG4105NX3 Membrane Aba5845_01555 ENOG4105EUJ GTP cyclohydrolase i Aba5845_01565 ENOG4105C7W Xanthine dehydrogenase Aba5845_01595 ENOG4105CD8 aminopeptidase N Aba5845_01600 ENOG4105DDQ anthranilate synthase Aba5845_01610 ENOG4105DUX Transporter Aba5845_01615 ENOG4105C5F glutamine synthetase Aba5845_01625 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) Aba5845_01660 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) Aba5845_01665 ENOG4107QNR UPF0135 protein Aba5845_01670 ENOG4105C0H protease Aba5845_01680 ENOG4105C6K Malic enzyme Aba5845_01685 ENOG4105BZU Histidine kinase Aba5845_01690 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) Aba5845_01695 ENOG4105SYT Methylenetetrahydrofolate reductase Aba5845_01700 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) Aba5845_01715 ENOG4107QPN acyl-Coa dehydrogenase Aba5845_01720 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) Aba5845_01725 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) Aba5845_01735 ENOG4107RNU major facilitator superfamily MFS_1 Aba5845_01745 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) Aba5845_01750 ENOG4105CE9 30S ribosomal protein S2 Aba5845_01790 ENOG4105CVE Lytic murein transglycosylase Aba5845_01795 ENOG4105CNI cell division protein FtsW Aba5845_01810 ENOG4105E3A (ABC) transporter Aba5845_01815 ENOG4105DA5 (ABC) transporter Aba5845_01850 ENOG4105ENJ RND efflux system, outer membrane lipoprotein Aba5845_01860 ENOG4105ENT Efflux transporter rnd family, mfp subunit Aba5845_01870 ENOG4105E89 ABC transporter Aba5845_01875 ENOG4105DSP amino acid AbC transporter Aba5845_01880 ENOG4106YG3 ABC transporter Aba5845_01885 ENOG4108JEH abc transporter atp-binding protein Aba5845_01895 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding Aba5845_01900 ENOG4105CFP Peptidase U32 Aba5845_01905 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Aba5845_01910 ENOG4105JAB phenazine biosynthesis protein, phzf family Aba5845_01915 ENOG4105DP0 ferredoxin-NADP reductase Aba5845_01920 ENOG4108R96 Methyltransferase, YaeB family Aba5845_01930 ENOG4107QHF type ii secretion system protein e Aba5845_01940 ENOG4105XJC Two component transcriptional regulator (Winged helix family Aba5845_01945 ENOG4105DHQ Histidine kinase Aba5845_01955 ENOG4105M6F mutator MutT protein Aba5845_01965 ENOG4105BZ4 penicillin-binding protein Aba5845_01970 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) Aba5845_01975 ENOG4105VUT cytoplasmic protein Aba5845_01980 ENOG4107QYG anthranilate phosphoribosyltransferase Aba5845_01990 ENOG4105CK2 sodium dicarboxylate symporter Aba5845_01995 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_02000 ENOG4105NIV Esterase Aba5845_02005 ENOG4105CQC Prephenate dehydratase Aba5845_02010 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase Aba5845_02020 ENOG4105CIN aminoacyl-histidine dipeptidase Aba5845_02025 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) Aba5845_02055 ENOG4105M08 Membrane Aba5845_02060 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Aba5845_02070 ENOG4105VEQ Cold shock protein Aba5845_02075 ENOG4105C1J atp-dependent rna helicase Aba5845_02085 ENOG41069NU Nitroreductase Aba5845_02120 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase Aba5845_02135 ENOG4105C5I Dehydrogenase Aba5845_02140 ENOG4105ERG peptidase m48, ste24p Aba5845_02145 ENOG4105KTH gatB Yqey Aba5845_02150 ENOG4105VCC 30S ribosomal protein S21 Aba5845_02175 ENOG4105D9P serine threonine protein kinase Aba5845_02200 ENOG4105EVZ LysR family transcriptional regulator Aba5845_02205 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) Aba5845_02210 ENOG4105C26 Dehydrogenase Aba5845_02245 ENOG4105H4F exported protein Aba5845_02275 ENOG4105D6U Sodium Glutamate Symporter Aba5845_02285 ENOG4105JXH GntR family transcriptional regulator Aba5845_02335 ENOG4105CSH Transporter Aba5845_02360 ENOG4105CEB Aspartate aminotransferase Aba5845_02375 ENOG4105F1S paraquat-inducible protein a Aba5845_02380 ENOG4105DY2 Paraquat-inducible protein b Aba5845_02475 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) Aba5845_02550 ENOG4105CK2 sodium dicarboxylate symporter Aba5845_02560 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) Aba5845_02565 ENOG4108UMI ABC transporter, permease Aba5845_02570 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) Aba5845_02580 ENOG4105C12 Phosphoribosylglycinamide synthetase Aba5845_02585 ENOG4105DC1 bifunctional purine biosynthesis protein purh Aba5845_02590 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) Aba5845_02640 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) Aba5845_02645 ENOG4105CDU Replicative dna helicase Aba5845_02670 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) Aba5845_02675 ENOG4105CCU oxidase (Subunit III) Aba5845_02680 ENOG4105BZ9 Cytochrome C oxidase, subunit I Aba5845_02685 ENOG4105E2S oxidase) subunit II Aba5845_02710 ENOG4107BJW polysaccharide deacetylase Aba5845_02715 ENOG4105CND Glycosyl transferase, family 2 Aba5845_02720 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD Aba5845_02730 ENOG4105DEN Luciferase family Aba5845_02750 ENOG4105CC0 LysR family Transcriptional regulator Aba5845_02765 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) Aba5845_02770 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component Aba5845_02775 ENOG4105GVF (ABC) transporter Aba5845_02790 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_02800 ENOG4108MEJ flavin reductase domain protein Aba5845_02805 ENOG4105D06 uba thif-type nad fad binding protein Aba5845_02825 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) Aba5845_02830 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) Aba5845_02840 ENOG4105C08 Histidine kinase Aba5845_02845 ENOG4105EEX Two component transcriptional regulator (Winged helix family Aba5845_02850 ENOG4105CFQ glutamine synthetase Aba5845_02865 ENOG4107S74 Lysophospholipid transporter LplT Aba5845_02870 ENOG4105CFU surface antigen Aba5845_02890 ENOG4107QIJ Aconitate hydratase 2 Aba5845_02900 ENOG4105EYW Ion transport protein Aba5845_02905 ENOG4105F27 Major Facilitator Aba5845_02920 ENOG4105DZ2 Transcriptional regulator Aba5845_02955 ENOG4105K8N protein family UPF0079, ATPase Aba5845_02960 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) Aba5845_02970 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) Aba5845_02975 ENOG4108TZV Membrane Aba5845_02980 ENOG4108RCM Nitroreductase Aba5845_02990 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) Aba5845_03005 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) Aba5845_03010 ENOG4107FQ9 ethanolamine ammonia-lyase Aba5845_03015 ENOG4105CPD ethanolamine ammonia-lyase Aba5845_03020 ENOG4107R55 ethanolamine transporter Aba5845_03030 ENOG4107RR1 TRANSCRIPTIONal Aba5845_03040 ENOG4105C0A alcohol dehydrogenase Aba5845_03045 ENOG4107QUV Domain protein Aba5845_03055 ENOG4105F4I Transcriptional regulator Aba5845_03075 ENOG4105CD8 aminopeptidase N Aba5845_03085 ENOG4105EMU Dehydrogenase Aba5845_03095 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) Aba5845_03100 ENOG4105EW9 transcriptional regulator AsnC family Aba5845_03115 ENOG4105R8C Transcriptional regulator Aba5845_03125 ENOG4105CUY Mechanosensitive ion channel Aba5845_03160 ENOG4105CNM Receptor Aba5845_03180 ENOG4105C5H ABC transporter Aba5845_03185 ENOG41081QV Universal stress protein Aba5845_03205 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic Aba5845_03215 ENOG4105DKK Benzoate Aba5845_03220 ENOG4105EW9 transcriptional regulator AsnC family Aba5845_03225 ENOG4108NIW Leucine export protein LeuE Aba5845_03230 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) Aba5845_03235 ENOG4105C5Q Transcriptional regulator Aba5845_03245 ENOG4105CHU acetyl-coa acetyltransferase Aba5845_03250 ENOG4105CHR reductase Aba5845_03275 ENOG4107QMP dna polymerase iii subunits gamma and tau Aba5845_03280 ENOG4105HSS phospholipase C Aba5845_03290 ENOG4105C0A alcohol dehydrogenase Aba5845_03320 ENOG4105CBC glutamate synthase Aba5845_03620 ENOG4105UPP uncharacterized protein ydcA Aba5845_03650 ENOG4105DR5 peptidase Aba5845_03745 ENOG4105D8G Major Facilitator superfamily Aba5845_03755 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase Aba5845_03760 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein Aba5845_03780 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Aba5845_03790 ENOG4107QZF nitrite reductase NADPH large subunit Aba5845_03795 ENOG4108IFG nitrite reductase, (NAD(P)H) Aba5845_03815 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) Aba5845_03830 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) Aba5845_03835 ENOG4105CVM Molybdenum cofactor synthesis domain protein Aba5845_03845 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Aba5845_03850 ENOG4105T38 integral membrane protein Aba5845_03870 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) Aba5845_03875 ENOG4105CMR udp-glucose 4-epimerase Aba5845_03940 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Aba5845_03945 ENOG4105CUX Signal transduction histidine kinase Aba5845_03965 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) Aba5845_03970 ENOG4105KNE Phosphatidate cytidylyltransferase Aba5845_03980 ENOG4105DZP Membrane-associated zinc metalloprotease Aba5845_04005 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) Aba5845_04020 ENOG4105Y3E Modulates RecA activity (By similarity) Aba5845_04030 ENOG4105VEJ Heat shock protein Aba5845_04035 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 Aba5845_04060 ENOG4105F7P transcriptional regulator AsnC family Aba5845_04070 ENOG4105C85 amino acid Aba5845_04090 ENOG4105CHH sulfate transporter Aba5845_04095 ENOG4108RAV Conserved protein Aba5845_04100 ENOG4105D8V Glucose sorbosone dehydrogenase Aba5845_04110 ENOG4105BZU Histidine kinase Aba5845_04130 ENOG4105DM4 PTS System Aba5845_04135 ENOG4105DE4 1-phosphofructokinase Aba5845_04140 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) Aba5845_04165 ENOG4105CWM branched-chain amino acid transport system II carrier protein Aba5845_04170 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) Aba5845_04175 ENOG4105CC0 LysR family Transcriptional regulator Aba5845_04185 ENOG4105M2J Glutaredoxin Aba5845_04190 ENOG4105C8Y Acetylornithine aminotransferase Aba5845_04195 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) Aba5845_04220 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) Aba5845_04230 ENOG41068P6 UPF0319 protein Aba5845_04250 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii Aba5845_04255 ENOG4105C4M (Ubiquinol oxidase) subunit I Aba5845_04265 ENOG4105PV3 Inner membrane protein yqiJ Aba5845_04280 ENOG4105E0K tonB-dependent siderophore receptor Aba5845_04290 ENOG4105HDD phospholipase Aba5845_04295 ENOG4105CZN Potassium uptake protein Aba5845_04305 ENOG4105C7B Threonine dehydratase Aba5845_04335 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) Aba5845_04340 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit Aba5845_04350 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) Aba5845_04365 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase Aba5845_04410 ENOG4107VMU Membrane Aba5845_04415 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) Aba5845_04425 ENOG4107QP7 CoA-transferase subunit A Aba5845_04430 ENOG4107QNJ CoA-transferase subunit B Aba5845_04435 ENOG4105CHU acetyl-coa acetyltransferase Aba5845_04440 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase Aba5845_04445 ENOG4105F2Z 3-oxoadipate enol-lactonase Aba5845_04450 ENOG4105D2S major facilitator superfamily Aba5845_04455 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase Aba5845_04460 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta Aba5845_04465 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha Aba5845_04470 ENOG4105FF2 Type I DHQase Aba5845_04475 ENOG4106JPM 3-dehydroshikimate dehydratase Aba5845_04480 ENOG4105TW1 Carbohydrate-selective porin OprB Aba5845_04485 ENOG4105DZG Dehydrogenase Aba5845_04495 ENOG4105MD1 YeeE YedE family protein Aba5845_04510 ENOG4107HP6 Transcriptional regulator Aba5845_04515 ENOG4108PTX LysR family Transcriptional regulator Aba5845_04520 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_04545 ENOG4105DNH Major Facilitator Aba5845_04555 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) Aba5845_04575 ENOG4105FUY alpha subunit Aba5845_04585 ENOG4105CHR reductase Aba5845_04605 ENOG4105F11 amine oxidase Aba5845_04615 ENOG4105C26 Dehydrogenase Aba5845_04625 ENOG4105F2Z 3-oxoadipate enol-lactonase Aba5845_04630 ENOG4105CHU acetyl-coa acetyltransferase Aba5845_04635 ENOG4107QNJ CoA-transferase subunit B Aba5845_04640 ENOG4107QP7 CoA-transferase subunit A Aba5845_04650 ENOG4105NN7 muconolactone delta-isomerase Aba5845_04655 ENOG4105DTQ mandelate racemase muconate lactonizing Aba5845_04660 ENOG4108KB2 LysR family Transcriptional regulator Aba5845_04670 ENOG4107EJG GntR family transcriptional regulator Aba5845_04690 ENOG4105CZJ Aldehyde dehydrogenase Aba5845_04710 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_04720 ENOG4108JU7 Transcriptional regulator Aba5845_04730 ENOG41062QD Membrane Aba5845_04745 ENOG4107RGH Aldehyde dehydrogenase Aba5845_04760 ENOG4105CH6 catalase Aba5845_04785 ENOG4105K56 Transcriptional regulator Aba5845_04790 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase Aba5845_04800 ENOG4105NAE bifunctional deaminase-reductase domain protein Aba5845_04830 ENOG4107Z3H Transcriptional regulator, TetR family Aba5845_04840 ENOG4105CHJ isochorismatase hydrolase Aba5845_04845 ENOG4105EJC lysr family transcriptional regulator Aba5845_04850 ENOG4105D8V Glucose sorbosone dehydrogenase Aba5845_04855 ENOG4105CKD glutathione-regulated potassium-efflux system protein Aba5845_04865 ENOG4105CH2 amidohydrolase Aba5845_04880 ENOG4105D5K Hemolysin activator protein Aba5845_04885 ENOG4105CKT filamentous hemagglutinin Aba5845_04915 ENOG4105FDP GntR family transcriptional regulator Aba5845_04930 ENOG4106KR7 LysR family Transcriptional regulator Aba5845_04955 ENOG4108JQ1 Dehydrogenase Aba5845_04960 ENOG4105JSC dimethylmenaquinone methyltransferase Aba5845_04980 ENOG4105CW7 secretion protein, HlyD family Aba5845_04995 ENOG4105CZJ Aldehyde dehydrogenase Aba5845_05000 ENOG4105C01 Dihydroxy-acid dehydratase Aba5845_05010 ENOG4105DDW LysR family Transcriptional regulator Aba5845_05015 ENOG4105EXW epimerase dehydratase Aba5845_05025 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase Aba5845_05030 ENOG4105CF7 AraC family transcriptional regulator Aba5845_05045 ENOG4105DQ4 alcohol dehydrogenase Aba5845_05055 ENOG4105EHG Permease protein Aba5845_05060 ENOG4105E0A ABC, transporter Aba5845_05080 ENOG4105C5T Phosphoribosyl pyrophosphate synthase Aba5845_05160 ENOG4108UAJ Transcriptional regulator Aba5845_05200 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) Aba5845_05250 ENOG4105CHR reductase Aba5845_05265 ENOG4108R6W Transcriptional regulator, ARAC family Aba5845_05270 ENOG4108821 RND type efflux pump Aba5845_05275 ENOG4105E0F Histidine kinase Aba5845_05280 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Aba5845_05285 ENOG4105C1P efflux transporter, rnd family, mfp subunit Aba5845_05290 ENOG4105BZS acriflavin resistance protein Aba5845_05295 ENOG4105ENJ RND efflux system, outer membrane lipoprotein Aba5845_05305 ENOG4105CT3 Monooxygenase Aba5845_05325 ENOG4105CJP fad dependent oxidoreductase Aba5845_05345 ENOG4105X0I Fimbrial Aba5845_05400 ENOG4107RZC phospholipase d Aba5845_05420 ENOG4108IGT Dipeptidase Aba5845_05455 ENOG4107T31 5'-nucleotidase Aba5845_05465 ENOG4105WQI isochorismatase Aba5845_05470 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase Aba5845_05475 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) Aba5845_05480 ENOG4105E0C molybdate abc transporter Aba5845_05485 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein Aba5845_05490 ENOG4105F4R Transcriptional regulator mode Aba5845_05495 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit Aba5845_05500 ENOG4108YS2 small subunit Aba5845_05505 ENOG4105F57 Anthranilate dioxygenase reductase Aba5845_05530 ENOG4105CHR reductase Aba5845_05540 ENOG4105D2S major facilitator superfamily Aba5845_05545 ENOG4105CF7 AraC family transcriptional regulator Aba5845_05555 ENOG4105DTD Dehydrogenase Aba5845_05560 ENOG4105CY2 Citrate transporter Aba5845_05570 ENOG4108M0I Transcriptional regulator Aba5845_05580 ENOG4107QNJ CoA-transferase subunit B Aba5845_05585 ENOG4105CRW Short chain fatty acid transporter Aba5845_05590 ENOG4105CHU acetyl-coa acetyltransferase Aba5845_05600 ENOG4107YNJ LysR family Transcriptional regulator Aba5845_05615 ENOG4108IJ0 Aspartate ammonia-lyase Aba5845_05625 ENOG4105CSH Transporter Aba5845_05645 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component Aba5845_05650 ENOG4106FTQ Taurine ABC transporter, periplasmic Aba5845_05665 ENOG4105FDP GntR family transcriptional regulator Aba5845_05675 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) Aba5845_05680 ENOG4105KVH Transcriptional regulator Aba5845_05685 ENOG4105UEI Transcriptional Regulator AraC Family Aba5845_05700 ENOG4108VCT Sulfite exporter TauE/SafE Aba5845_05710 ENOG4107QPB Beta-lactamase domain protein Aba5845_05720 ENOG4105FFC UPF0187 protein Aba5845_05730 ENOG4105CHR reductase Aba5845_05745 ENOG4105CPP Dehydrogenase, E1 component Aba5845_05750 ENOG4107R0V Pyruvate dehydrogenase Aba5845_05755 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) Aba5845_05770 ENOG4105BZU Histidine kinase Aba5845_05780 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) Aba5845_05785 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) Aba5845_05830 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) Aba5845_05845 ENOG4105C28 cystathionine Aba5845_05855 ENOG4105F2W methyltransferase Aba5845_05885 ENOG4105K59 histidine triad (HIT) protein Aba5845_05910 ENOG4107QWP ABC-2 type transporter Aba5845_05915 ENOG4107QWP ABC-2 type transporter Aba5845_05920 ENOG4105CJ1 ABC, transporter Aba5845_05935 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) Aba5845_05940 ENOG4105CNM Receptor Aba5845_05960 ENOG4107TSN permease Aba5845_05965 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) Aba5845_05985 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) Aba5845_05990 ENOG4108YZT Adenosylcobinamide kinase Aba5845_06040 ENOG4105DJU Siderophore biosynthesis protein Aba5845_06045 ENOG4105DUU IucA IucC family protein Aba5845_06065 ENOG4108Z66 YbaK ebsC protein Aba5845_06080 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_06085 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_06090 ENOG4105EEF Alkane 1-monooxygenase Aba5845_06095 ENOG4105E7U AraC family transcriptional regulator Aba5845_06100 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) Aba5845_06105 ENOG4105K70 DNA-binding protein Aba5845_06120 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family Aba5845_06130 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins Aba5845_06135 ENOG4108Z4V iron-sulfur cluster assembly Aba5845_06150 ENOG4108ZIT Ferredoxin, 2FE-2S Aba5845_06155 ENOG4105F8J Adenylate Guanylate cyclase Aba5845_06165 ENOG4108JA2 transcriptioN-repair coupling factor Aba5845_06185 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) Aba5845_06190 ENOG4105K4T epimerase Aba5845_06205 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase Aba5845_06225 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component Aba5845_06235 ENOG4105DGW oligopeptidase A Aba5845_06270 ENOG4105SG9 biopolymer transport protein, ExbD Aba5845_06280 ENOG4107QP3 malate synthase g Aba5845_06285 ENOG4105D6Z AFG1 family ATPase Aba5845_06295 ENOG4107RN6 Monooxygenase Aba5845_06315 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) Aba5845_06320 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) Aba5845_06335 ENOG4108Z6B deaminase Aba5845_06355 ENOG4108RTD type II secretion system protein K Aba5845_06380 ENOG4105F8V Hydrolase, tatD family Aba5845_06390 ENOG4107QRG dna polymerase iii Aba5845_06400 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) Aba5845_06405 ENOG4105BZ1 (ABC) transporter Aba5845_06420 ENOG4105FA0 parb-like partition protein Aba5845_06425 ENOG4107QJE Chromosome Partitioning Protein Aba5845_06435 ENOG4108S0S Nucleotidyl transferase Aba5845_06440 ENOG4105EHM Aminoglycoside phosphotransferase Aba5845_06445 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) Aba5845_06450 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) Aba5845_06455 ENOG4105D2N Aldolase Aba5845_06475 ENOG4108UHJ MAF-like protein Aba5845_06480 ENOG4105EZE Cupin 4 family protein Aba5845_06490 ENOG41080HT Transcriptional regulator, arsr family Aba5845_06500 ENOG4105XPP Protein of unknown function (DUF1275) Aba5845_06505 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme Aba5845_06510 ENOG4105BZ1 (ABC) transporter Aba5845_06520 ENOG4108ZX5 transcriptional regulator Aba5845_06530 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) Aba5845_06535 ENOG4105CK7 Sodium proline symporter Aba5845_06540 ENOG4105EW9 transcriptional regulator AsnC family Aba5845_06545 ENOG4105C26 Dehydrogenase Aba5845_06550 ENOG4105YGK Pfam:UPF0157 Aba5845_06565 ENOG4108T58 Mg2 transport protein CorA Aba5845_06575 ENOG4108YYC ycei family Aba5845_06585 ENOG4105CV1 Transketolase (EC 2.2.1.1) Aba5845_06610 ENOG4108HWY Beta-lactamase Aba5845_06630 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) Aba5845_06635 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) Aba5845_06655 ENOG4105X0I Fimbrial Aba5845_06660 ENOG4105GQR Chaperone Aba5845_06690 ENOG4108IPJ Membrane Aba5845_06700 ENOG4105ETS cytosine purines uracil thiamine allantoin Aba5845_06710 ENOG4105CC0 LysR family Transcriptional regulator Aba5845_06730 ENOG41067SE Tetr family transcriptional regulator Aba5845_06745 ENOG4105EW9 transcriptional regulator AsnC family Aba5845_06755 ENOG4105CDA abc transporter atp-binding protein Aba5845_06760 ENOG4105DRP amino acid AbC transporter Aba5845_06765 ENOG4105EAD ABC transporter Aba5845_06780 ENOG4107T8P acyl-Coa dehydrogenase Aba5845_06795 ENOG4105D01 (LipO)protein Aba5845_06800 ENOG4105D01 (LipO)protein Aba5845_06805 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) Aba5845_06810 ENOG4108UMI ABC transporter, permease Aba5845_06815 ENOG4105C3G gtp-binding protein Aba5845_06840 ENOG4108UMN azlc family Aba5845_06845 ENOG4105ZED uncharacterized protein ygaH Aba5845_06875 ENOG4105E7U AraC family transcriptional regulator Aba5845_06880 ENOG4108V06 Glutathione peroxidase Aba5845_06890 ENOG4105CHM Aminotransferase Aba5845_06905 ENOG4105C0B DNA polymerase III (alpha subunit) Aba5845_06930 ENOG4108JU3 Alkyl hydroperoxide reductase Aba5845_06945 ENOG4108KB2 LysR family Transcriptional regulator Aba5845_06950 ENOG4105D6J arsenicaL-resistance protein Aba5845_06955 ENOG41082YX Transcriptional regulator, arsr family Aba5845_06970 ENOG4105CPN adenine deaminase Aba5845_06980 ENOG4105CBN LysR family transcriptional regulator Aba5845_06990 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease Aba5845_07000 ENOG4105E2B Taurine dioxygenase Aba5845_07005 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component Aba5845_07010 ENOG4108IY8 ABC, transporter Aba5845_07015 ENOG4106FTQ Taurine ABC transporter, periplasmic Aba5845_07025 ENOG4105C54 Major Facilitator superfamily Aba5845_07050 ENOG4105C4M (Ubiquinol oxidase) subunit I Aba5845_07055 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii Aba5845_07065 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Aba5845_07070 ENOG4108K70 Transcriptional regulator Aba5845_07085 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase Aba5845_07090 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase Aba5845_07105 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) Aba5845_07110 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase Aba5845_07120 ENOG4105DXI Major Facilitator superfamily Aba5845_07140 ENOG41067MG lrgb family Aba5845_07145 ENOG4105VAW lrga family Aba5845_07150 ENOG4105CMU LysR family (Transcriptional regulator Aba5845_07155 ENOG4108SHQ Glutathione S-transferase Aba5845_07160 ENOG4105CYM Glutathione S-transferase Aba5845_07165 ENOG4105CBN LysR family transcriptional regulator Aba5845_07170 ENOG4105CHR reductase Aba5845_07180 ENOG4105D7W serine acetyltransferase Aba5845_07185 ENOG4105ESN nucleotide-binding protein Aba5845_07190 ENOG4105C9B Cysteine desulfurase Aba5845_07200 ENOG4105EXG Transcriptional regulator Aba5845_07210 ENOG4105CT1 (ABC) transporter Aba5845_07215 ENOG4107RP9 extracellular solute-binding protein, family 3 Aba5845_07220 ENOG4105CDA abc transporter atp-binding protein Aba5845_07225 ENOG4108HW4 amino acid AbC transporter Aba5845_07230 ENOG4105EAD ABC transporter Aba5845_07245 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Aba5845_07250 ENOG4105BZU Histidine kinase Aba5845_07260 ENOG4105EW9 transcriptional regulator AsnC family Aba5845_07270 ENOG4105KT5 UmuD protein Aba5845_07290 ENOG4105CYX Short-chain dehydrogenase reductase Sdr Aba5845_07335 ENOG4105HEI LysR family (Transcriptional regulator Aba5845_07355 ENOG4105CEY Amp-dependent synthetase and ligase Aba5845_07360 ENOG4105R8C Transcriptional regulator Aba5845_07365 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_07370 ENOG4107QX3 carboxylase Aba5845_07375 ENOG4105E39 Enoyl-CoA hydratase Aba5845_07390 ENOG4105CC0 LysR family Transcriptional regulator Aba5845_07405 ENOG4105CSU acyl-Coa dehydrogenase Aba5845_07415 ENOG4105EQ0 Major Facilitator superfamily Aba5845_07425 ENOG4107QNJ CoA-transferase subunit B Aba5845_07430 ENOG4107QP7 CoA-transferase subunit A Aba5845_07435 ENOG4107RGD Major Facilitator superfamily Aba5845_07440 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_07445 ENOG4105E39 Enoyl-CoA hydratase Aba5845_07450 ENOG4105CHR reductase Aba5845_07460 ENOG4105CHU acetyl-coa acetyltransferase Aba5845_07470 ENOG4105EQ0 Major Facilitator superfamily Aba5845_07475 ENOG4105EA8 2-Nitropropane dioxygenase Aba5845_07480 ENOG4108UKI Enoyl-CoA hydratase Aba5845_07495 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_07500 ENOG4107RGD Major Facilitator superfamily Aba5845_07505 ENOG4108KAZ Involved in phosphonate degradation (By similarity) Aba5845_07510 ENOG4107STF Involved in phosphonate degradation (By similarity) Aba5845_07520 ENOG4107RCV ABC transporter, permease Aba5845_07525 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) Aba5845_07530 ENOG4105C4Y ABC transporter Aba5845_07540 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase Aba5845_07545 ENOG4107HP6 Transcriptional regulator Aba5845_07555 ENOG4105HEI LysR family (Transcriptional regulator Aba5845_07560 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase Aba5845_07565 ENOG4105C26 Dehydrogenase Aba5845_07575 ENOG4105ETS cytosine purines uracil thiamine allantoin Aba5845_07585 ENOG4105C26 Dehydrogenase Aba5845_07590 ENOG4108M8W Monooxygenase Aba5845_07595 ENOG4105MXW flavin reductase domain protein, FMN-binding Aba5845_07600 ENOG4108MXF Alpha Beta Hydrolase Aba5845_07620 ENOG4105CPW cytochrome b561 Aba5845_07625 ENOG4107VGR Catalase Aba5845_07665 ENOG4107YAU phenylacetic acid degradation protein Aba5845_07675 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein Aba5845_07680 ENOG4105DZS Phenylacetate-CoA ligase Aba5845_07685 ENOG4105CHU acetyl-coa acetyltransferase Aba5845_07690 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase Aba5845_07695 ENOG4108UKI Enoyl-CoA hydratase Aba5845_07700 ENOG4105E39 Enoyl-CoA hydratase Aba5845_07705 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) Aba5845_07710 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit Aba5845_07715 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit Aba5845_07720 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit Aba5845_07725 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit Aba5845_07730 ENOG4105DXM phenylacetic acid degradation protein Aba5845_07735 ENOG4105EJQ L-serine dehydratase Aba5845_07740 ENOG4107QTZ amino acid Aba5845_07745 ENOG4105CZJ Aldehyde dehydrogenase Aba5845_07770 ENOG4105MWK D-amino acid dehydrogenase, small subunit Aba5845_07790 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) Aba5845_07805 ENOG4108Z4X TRANSCRIPTIONal Aba5845_07820 ENOG4105WPN DNA integration recombination invertion protein Aba5845_07835 ENOG4105DJ2 Major Facilitator Superfamily Aba5845_07840 ENOG4107Y2X deaminase Aba5845_07850 ENOG4105EMY transcriptional regulator Aba5845_07880 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit Aba5845_07890 ENOG4105UYK outer membrane protein a Aba5845_07965 ENOG4108HW3 (ABC) transporter Aba5845_07975 ENOG4105MRR Transcriptional regulator (By similarity) Aba5845_07995 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF Aba5845_08000 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase Aba5845_08015 ENOG4105E2A Dehydrogenase Aba5845_08025 ENOG4105R8C Transcriptional regulator Aba5845_08050 ENOG4107R4J Chloride channel Aba5845_08055 ENOG4108JIK carboxylase Aba5845_08075 ENOG4105C5A transporter Aba5845_08080 ENOG4108WAV Transcriptional regulator Aba5845_08095 ENOG4105CNA YD repeat protein Aba5845_08135 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) Aba5845_08155 ENOG4105D2S major facilitator superfamily Aba5845_08170 ENOG4105D1S lipid A biosynthesis Aba5845_08175 ENOG4105BZU Histidine kinase Aba5845_08180 ENOG4107AQZ Membrane Aba5845_08200 ENOG4108Z4U Ferredoxin Aba5845_08240 ENOG4105DFG type I secretion outer membrane protein Aba5845_08245 ENOG4108IUZ ABC transporter Aba5845_08250 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA Aba5845_08260 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase Aba5845_08265 ENOG4105C2X Arabinose 5-phosphate isomerase Aba5845_08300 ENOG4107YPT transcriptional regulator Aba5845_08335 ENOG4105II7 pyrroline-5-carboxylate reductase Aba5845_08345 ENOG4105VEQ Cold shock protein Aba5845_08350 ENOG410829K Lysine exporter protein (Lyse ygga) Aba5845_08390 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) Aba5845_08445 ENOG4108KB2 LysR family Transcriptional regulator Aba5845_08450 ENOG4105FUY alpha subunit Aba5845_08455 ENOG4108UKV benzoate 1,2-dioxygenase Aba5845_08460 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein Aba5845_08465 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase Aba5845_08470 ENOG4105DKK Benzoate Aba5845_08475 ENOG4105D2S major facilitator superfamily Aba5845_08490 ENOG4105CQ7 ATP-dependent helicase Aba5845_08495 ENOG4105D3R alkyl hydroperoxide reductase Aba5845_08505 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) Aba5845_08515 ENOG4108JU3 Alkyl hydroperoxide reductase Aba5845_08525 ENOG4108K3A Glutathione S-transferase Aba5845_08535 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) Aba5845_08540 ENOG4108TGY Glutathione S-transferase Aba5845_08550 ENOG4108ZG0 Ompa motb domain protein Aba5845_08555 ENOG4105CD3 dihydroorotase Aba5845_08585 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit Aba5845_08605 ENOG4107RYR Transcriptional regulator, Crp Fnr family Aba5845_08615 ENOG4108UKZ OsmC family Aba5845_08625 ENOG4105CPC Aldo Keto reductase Aba5845_08640 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis Aba5845_08650 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase Aba5845_08660 ENOG4105CFH Aspartokinase Aba5845_08670 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) Aba5845_08680 ENOG4105CPW cytochrome b561 Aba5845_08685 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) Aba5845_08690 ENOG4105C7N Xanthine uracil vitamin C permease Aba5845_08700 ENOG4105F95 Monooxygenase Aba5845_08775 ENOG4108C33 Resolvase Aba5845_08780 ENOG4105D13 transposase Aba5845_08815 ENOG4105C85 amino acid Aba5845_08835 ENOG4105C26 Dehydrogenase Aba5845_08855 ENOG4105CUB amino acid Aba5845_08865 ENOG4105C85 amino acid Aba5845_08910 ENOG4105CNA YD repeat protein Aba5845_08930 ENOG4105D01 (LipO)protein Aba5845_08935 ENOG4108M3P Membrane Aba5845_08950 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase Aba5845_08970 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) Aba5845_08990 ENOG4108JQ5 ABC transporter Aba5845_08995 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component Aba5845_09000 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component Aba5845_09010 ENOG4105E9H Lytic Murein transglycosylase Aba5845_09010 ENOG4105E9H Lytic Murein transglycosylase Aba5845_09015 ENOG4107RZZ dna polymerase iii epsilon subunit Aba5845_09025 ENOG4105E09 nadh pyrophosphatase Aba5845_09035 ENOG4105W4M Transport-associated protein Aba5845_09045 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) Aba5845_09055 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) Aba5845_09060 ENOG4108ZUB Lysine exporter protein (Lyse ygga) Aba5845_09080 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family Aba5845_09085 ENOG4105D0A hydroxylase Aba5845_09090 ENOG4107RAQ aminopeptidase Aba5845_09170 ENOG4105E4C Lytic transglycosylase catalytic Aba5845_09225 ENOG4105EFC phage portal protein HK97 family Aba5845_09320 ENOG4105CDU Replicative dna helicase Aba5845_09340 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) Aba5845_09395 ENOG4105DIJ Phosphoethanolamine transferase Aba5845_09440 ENOG4105DR5 peptidase Aba5845_09765 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase Aba5845_09790 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b Aba5845_09800 ENOG4105D82 Glutamate dehydrogenase Aba5845_09805 ENOG4108R3D Electron transport complex Aba5845_09810 ENOG4105CSM endonuclease III Aba5845_09835 ENOG4105CJN penicillin-binding protein Aba5845_09840 ENOG4106H78 methyltransferase Aba5845_09855 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) Aba5845_09865 ENOG4105CQM Urea amidohydrolase subunit alpha Aba5845_09895 ENOG4107RET Isocitrate lyase Aba5845_09905 ENOG4105C37 (CBS) domain Aba5845_09915 ENOG4105D4T Citrate transporter Aba5845_09930 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) Aba5845_09945 ENOG4108MRJ Aba5845_09965 ENOG4105VCQ rubredoxin Aba5845_09970 ENOG4107QZF nitrite reductase NADPH large subunit Aba5845_09980 ENOG4105C5Q Transcriptional regulator Aba5845_10005 ENOG4107U91 Rhomboid family Aba5845_10010 ENOG4105CV6 ABC transporter, permease Aba5845_10015 ENOG4108I0Y (ABC) transporter Aba5845_10020 ENOG4108UJV acyl-CoA thioesterase i Aba5845_10040 ENOG4107RNH Outer membrane receptor FepA Aba5845_10055 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) Aba5845_10060 ENOG4105E6M Sulphatase-modifying factor protein Aba5845_10080 ENOG4105CJ3 phosphate transporter Aba5845_10085 ENOG4105C3R Methionine synthase Aba5845_10100 ENOG4105CSP Major Facilitator Superfamily Aba5845_10110 ENOG4108PZW LysR family Transcriptional regulator Aba5845_10125 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) Aba5845_10130 ENOG4105EU0 Major facilitator Superfamily Aba5845_10135 ENOG4108R6W Transcriptional regulator, ARAC family Aba5845_10140 ENOG4105CSV Glutaminase Aba5845_10145 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) Aba5845_10150 ENOG4105CSH Transporter Aba5845_10160 ENOG4105C7K acetolactate synthase Aba5845_10175 ENOG4105CHR reductase Aba5845_10180 ENOG4108MXF Alpha Beta Hydrolase Aba5845_10190 ENOG4105DJB Major Facilitator Superfamily Aba5845_10195 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase Aba5845_10205 ENOG4105CHR reductase Aba5845_10225 ENOG41069M3 Transcriptional regulator Aba5845_10240 ENOG4106YT9 Enoyl-CoA hydratase Aba5845_10250 ENOG4105CND Glycosyl transferase, family 2 Aba5845_10255 ENOG4107BJW polysaccharide deacetylase Aba5845_10265 ENOG4108VWS Yaeq family Aba5845_10275 ENOG4105CKI cobalamin synthesis protein Aba5845_10295 ENOG4105C94 Transporter Aba5845_10300 ENOG4105C94 Transporter Aba5845_10305 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) Aba5845_10330 ENOG4107QK5 Homocysteine s-methyltransferase Aba5845_10335 ENOG4105D5Q Arginine ornithine antiporter Aba5845_10360 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) Aba5845_10365 ENOG4105C54 Major Facilitator superfamily Aba5845_10485 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) Aba5845_10525 ENOG4105K4U addiction module toxin, RelE StbE family Aba5845_10675 ENOG4105VTN Protein of unknown function (DUF1311) Aba5845_10810 ENOG41083X2 DNA polymerase III, epsilon subunit Aba5845_10875 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) Aba5845_10880 ENOG4105C0R drug resistance transporter emrb qaca subfamily Aba5845_10885 ENOG4105CW7 secretion protein, HlyD family Aba5845_10890 ENOG4108VUY thioesterase Superfamily protein Aba5845_10895 ENOG4105D52 delta-aminolevulinic acid dehydratase Aba5845_10900 ENOG4105MWK D-amino acid dehydrogenase, small subunit Aba5845_10905 ENOG4105ECP epimerase Aba5845_10925 ENOG4107RH8 nuclease SbcCD subunit D Aba5845_10930 ENOG4105EYH Exonuclease Aba5845_10935 ENOG4105DFA alanine racemase domain protein Aba5845_10940 ENOG4105CZX twitching motility protein Aba5845_10945 ENOG4105CZX twitching motility protein Aba5845_10950 ENOG41090R7 Ferric uptake Aba5845_10980 ENOG4105E7A Glutamine amidotransferase Aba5845_10995 ENOG4107QKV phosphomannomutase Aba5845_11005 ENOG4105C4R Atp-dependent dna helicase Aba5845_11010 ENOG4108ZG0 Ompa motb domain protein Aba5845_11015 ENOG4106HNH Acyl-transferase Aba5845_11030 ENOG4107QMS site-determining protein Aba5845_11055 ENOG4105CNU cell division protein FtsK Aba5845_11060 ENOG4105C3M thioredoxin reductase Aba5845_11065 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) Aba5845_11075 ENOG4105KEG ribosomal-protein-alanine acetyltransferase Aba5845_11120 ENOG4108YXA Membrane Aba5845_11125 ENOG4105EUB pirin domain protein Aba5845_11135 ENOG4105C4K Nad synthetase Aba5845_11150 ENOG4105E3J oxidoreductase Aba5845_11155 ENOG4105C26 Dehydrogenase Aba5845_11160 ENOG4105DVW rieske (2Fe-2S) Aba5845_11170 ENOG4105C94 Transporter Aba5845_11175 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) Aba5845_11180 ENOG4105EJC lysr family transcriptional regulator Aba5845_11200 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding Aba5845_11220 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase Aba5845_11225 ENOG4105C34 Pseudouridine synthase Aba5845_11230 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane Aba5845_11235 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) Aba5845_11250 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) Aba5845_11280 ENOG4105C5T Phosphoribosyl pyrophosphate synthase Aba5845_11310 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) Aba5845_11320 ENOG4105DWF phosphomethylpyrimidine kinase Aba5845_11325 ENOG4109066 lysm domain bon superfamily protein Aba5845_11335 ENOG4105CHR reductase Aba5845_11340 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase Aba5845_11350 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein Aba5845_11355 ENOG4108BPE -transporting atpase Aba5845_11360 ENOG4107RTD sua5 ycio yrdc ywlc family protein Aba5845_11365 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) Aba5845_11370 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) Aba5845_11375 ENOG4105FE9 pseudouridine synthase Aba5845_11385 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) Aba5845_11390 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) Aba5845_11400 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) Aba5845_11405 ENOG4108K4C ec 3.1.3.12 Aba5845_11410 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase Aba5845_11415 ENOG4106UW1 Major Facilitator superfamily Aba5845_11435 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) Aba5845_11445 ENOG4105HF0 Membrane Aba5845_11460 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY Aba5845_11470 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) Aba5845_11525 ENOG4105D1F ATP-binding protein Aba5845_11535 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) Aba5845_11565 ENOG4105K6H D-cysteine desulfhydrase Aba5845_11570 ENOG4105CBX hi0933 family Aba5845_11595 ENOG4105DP0 ferredoxin-NADP reductase Aba5845_11600 ENOG4105DUM transcriptional regulator, lysR family Aba5845_11620 ENOG4105C8S subunit m Aba5845_11625 ENOG4105D65 subunit l Aba5845_11635 ENOG4107UFS subunit j Aba5845_11650 ENOG4108IEH NADH dehydrogenase subunit g Aba5845_11655 ENOG4107QIZ NADH dehydrogenase Aba5845_11660 ENOG4105GKE subunit e Aba5845_11680 ENOG4105BZU Histidine kinase Aba5845_11690 ENOG4105E0F Histidine kinase Aba5845_11695 ENOG4107EXC regulatoR Aba5845_11705 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) Aba5845_11715 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) Aba5845_11725 ENOG4105EB3 Histidine kinase Aba5845_11795 ENOG4105DZG Dehydrogenase Aba5845_11815 ENOG4105JAB phenazine biosynthesis protein, phzf family Aba5845_11845 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) Aba5845_11850 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) Aba5845_11860 ENOG4105ETT transcriptional Regulator, LysR family Aba5845_11880 ENOG4105CH2 amidohydrolase Aba5845_11890 ENOG4106P55 Transcriptional regulator Aba5845_11910 ENOG4106P55 Transcriptional regulator Aba5845_11915 ENOG4107EFR Flavocytochrome c Aba5845_11925 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F Aba5845_11930 ENOG4107RGD Major Facilitator superfamily Aba5845_11935 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_11940 ENOG4105ETT transcriptional Regulator, LysR family Aba5845_11975 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) Aba5845_11980 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) Aba5845_11985 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) Aba5845_12000 ENOG4105VR0 copper resistance Aba5845_12005 ENOG4105E3B Multicopper oxidase Aba5845_12015 ENOG4108HCJ Hydrolase Aba5845_12020 ENOG4105DJV ribulose-phosphate 3-epimerase Aba5845_12045 ENOG41072GX Peptidase M22 Glycoprotease Aba5845_12050 ENOG4108Z0R Transferase Aba5845_12100 ENOG4105CRQ synthase (Component I) Aba5845_12110 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) Aba5845_12115 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) Aba5845_12120 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) Aba5845_12190 ENOG4105K56 Transcriptional regulator Aba5845_12195 ENOG4108ZHJ Organic hydroperoxide resistance protein Aba5845_12200 ENOG4107QHF type ii secretion system protein e Aba5845_12220 ENOG4105C2M dna polymerase I Aba5845_12225 ENOG4108VIA integral membrane protein Aba5845_12230 ENOG4105II7 pyrroline-5-carboxylate reductase Aba5845_12235 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) Aba5845_12245 ENOG4105C9X ppx gppa phosphatase Aba5845_12255 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) Aba5845_12275 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) Aba5845_12300 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) Aba5845_12315 ENOG4105W39 Membrane Aba5845_12320 ENOG4105CYM Glutathione S-transferase Aba5845_12340 ENOG4105CEY Amp-dependent synthetase and ligase Aba5845_12345 ENOG4105N42 UPF0307 protein Aba5845_12350 ENOG41080Z8 PHOSPHOCARRIER protein Aba5845_12370 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Aba5845_12375 ENOG4105DJ0 Poly(A) Polymerase Aba5845_12380 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein Aba5845_12385 ENOG4105DXN mazG family Aba5845_12395 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) Aba5845_12410 ENOG4105C6T cysteine synthase Aba5845_12415 ENOG4105BZU Histidine kinase Aba5845_12420 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase Aba5845_12425 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase Aba5845_12430 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) Aba5845_12445 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) Aba5845_12450 ENOG4105W8H transhydrogenase (subunit alpha Aba5845_12455 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) Aba5845_12460 ENOG4106UX7 integral membrane protein Aba5845_12475 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) Aba5845_12485 ENOG4107RSM transcriptional regulator Aba5845_12495 ENOG4105CUZ uba thif-type nad fad binding protein Aba5845_12505 ENOG4107QM5 aconitate hydratase Aba5845_12510 ENOG4105F8V Hydrolase, tatD family Aba5845_12525 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) Aba5845_12550 ENOG4105BZU Histidine kinase Aba5845_12560 ENOG4108ZP8 Acetolactate synthase small subunit Aba5845_12565 ENOG4105C7K acetolactate synthase Aba5845_12590 ENOG4105DJY efflux transporter, rnd family, mfp subunit Aba5845_12595 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Aba5845_12600 ENOG4105ENJ RND efflux system, outer membrane lipoprotein Aba5845_12605 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH Aba5845_12615 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) Aba5845_12620 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) Aba5845_12630 ENOG4105VW4 glutaredoxin 3 Aba5845_12650 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) Aba5845_12655 ENOG4105C2D reductase Aba5845_12665 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) Aba5845_12695 ENOG4105C84 Histidine ammonia-lyase Aba5845_12710 ENOG4105CEY Amp-dependent synthetase and ligase Aba5845_12725 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) Aba5845_12745 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) Aba5845_12765 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) Aba5845_12785 ENOG4105WVQ Fe-S assembly protein IscX Aba5845_12800 ENOG4105CN1 protease Aba5845_12815 ENOG4106HB6 Alpha beta hydrolase Aba5845_12825 ENOG4105C26 Dehydrogenase Aba5845_12830 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family Aba5845_12835 ENOG4105C6Z Gluconate Aba5845_12840 ENOG4108UHU Aldolase Aba5845_12845 ENOG4105C01 Dihydroxy-acid dehydratase Aba5845_12850 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) Aba5845_12855 ENOG4108DNC Involved in acetate metabolism (By similarity) Aba5845_12860 ENOG4107GFK fumarate Aba5845_12880 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) Aba5845_12890 ENOG4108ESX Receptor Aba5845_12900 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) Aba5845_12910 ENOG4105DWV Homoserine O-trans-acetylase Aba5845_13010 ENOG4105CIY formyltetrahydrofolate deformylase Aba5845_13020 ENOG4107RGH Aldehyde dehydrogenase Aba5845_13025 ENOG4105KDC 50s ribosomal protein l28 Aba5845_13030 ENOG4105W0E 50S ribosomal protein L33 Aba5845_13035 ENOG4105CKD glutathione-regulated potassium-efflux system protein Aba5845_13055 ENOG4105VFU Rna-binding protein Aba5845_13060 ENOG4105C4R Atp-dependent dna helicase Aba5845_13075 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) Aba5845_13085 ENOG4105KVH Transcriptional regulator Aba5845_13095 ENOG41069P5 Protein slyX homolog Aba5845_13100 ENOG4105C5H ABC transporter Aba5845_13105 ENOG4105N14 lysine exporter protein LysE YggA Aba5845_13110 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase Aba5845_13120 ENOG4105CK2 sodium dicarboxylate symporter Aba5845_13175 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) Aba5845_13200 ENOG4105DUM transcriptional regulator, lysR family Aba5845_13225 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase Aba5845_13240 ENOG4108W5M transcriptional regulator Aba5845_13255 ENOG4105D29 Helix-turn-helix type 11 domain protein Aba5845_13260 ENOG4107XGZ Hydrolase Aba5845_13265 ENOG4105EI2 Pseudouridine synthase Aba5845_13275 ENOG4105C03 ribonuclease Aba5845_13295 ENOG4105CBN LysR family transcriptional regulator Aba5845_13300 ENOG4105EMU Dehydrogenase Aba5845_13305 ENOG4105CSA Coproporphyrinogen iii oxidase Aba5845_13315 ENOG4107QI1 Mate efflux family protein Aba5845_13325 ENOG4107T8P acyl-Coa dehydrogenase Aba5845_13370 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) Aba5845_13375 ENOG4105C5X domain protein Aba5845_13390 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) Aba5845_13400 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase Aba5845_13405 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) Aba5845_13410 ENOG4108JU5 Magnesium and cobalt efflux protein Aba5845_13415 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) Aba5845_13420 ENOG4108Z7R Chaperone CsaA Aba5845_13430 ENOG4108VAU general secretion pathway protein G Aba5845_13435 ENOG4105D7Q type ii secretion system Aba5845_13440 ENOG4105C25 Primosomal protein n' Aba5845_13445 ENOG4105CKD glutathione-regulated potassium-efflux system protein Aba5845_13450 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) Aba5845_13460 ENOG4105DVC DnaJ domain protein Aba5845_13465 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) Aba5845_13470 ENOG4107QUT magnesium and cobalt transport protein CorA Aba5845_13490 ENOG4107QYX exodeoxyribonuclease v alpha Aba5845_13495 ENOG4107QKA exodeoxyribonuclease V beta Aba5845_13500 ENOG4105DSY exodeoxyribonuclease V, gamma Aba5845_13510 ENOG4105CSR polyphosphate kinase 2 Aba5845_13520 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) Aba5845_13535 ENOG41061H0 Monooxygenase Aba5845_13540 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase Aba5845_13555 ENOG4105D65 subunit l Aba5845_13560 ENOG4108ZE9 Monovalent cation H antiporter subunit C Aba5845_13565 ENOG4107R4Z monovalent cation h antiporter subunit d Aba5845_13570 ENOG4105SC1 monovalent cation H antiporter subunit E Aba5845_13575 ENOG4105W4C monovalent cation H antiporter subunit F Aba5845_13580 ENOG4105KJM monovalent cation h antiporter subunit g Aba5845_13595 ENOG4105CHV Transcription elongation factor NusA Aba5845_13620 ENOG4107EJC Preprotein translocase subunit SecG Aba5845_13630 ENOG4107QHF type ii secretion system protein e Aba5845_13645 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) Aba5845_13655 ENOG4105C2N RNA methyltransferase TrmH family group 3 Aba5845_13670 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) Aba5845_13680 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) Aba5845_13710 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) Aba5845_13715 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase Aba5845_13785 ENOG4107ZXU DSBA oxidoreductase Aba5845_13805 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) Aba5845_13820 ENOG4105D3Y Na H antiporter Aba5845_13825 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) Aba5845_13875 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) Aba5845_13880 ENOG4105PM1 preprotein translocase subunit SecE Aba5845_13920 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) Aba5845_13925 ENOG4105TV9 FHA Domain-Containing protein Aba5845_13930 ENOG4105GVR general secretion pathway protein D Aba5845_13945 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS Aba5845_13970 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) Aba5845_13975 ENOG4108NEV two component transcriptional regulator, LytTR family Aba5845_13980 ENOG4108HRK Histidine kinase Aba5845_13995 ENOG4108UTW Plays a role in the regulation of phosphate uptake Aba5845_14000 ENOG4105DFG type I secretion outer membrane protein Aba5845_14005 ENOG4108RNG Permease of the drug metabolite transporter Aba5845_14030 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) Aba5845_14035 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters Aba5845_14040 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) Aba5845_14045 ENOG4105CNI cell division protein FtsW Aba5845_14060 ENOG4105CE1 Ferrous iron transport protein b Aba5845_14070 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Aba5845_14075 ENOG4105T95 Thiol disulfide interChange protein Aba5845_14080 ENOG4105D6E homoserine dehydrogenase Aba5845_14090 ENOG41061WM D-Alanyl-D-Alanine Aba5845_14100 ENOG4107TUY Histidine kinase Aba5845_14105 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Aba5845_14110 ENOG4105CN1 protease Aba5845_14115 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) Aba5845_14120 ENOG4108K5H permease YjgP YjgQ family protein Aba5845_14160 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) Aba5845_14170 ENOG4105BZU Histidine kinase Aba5845_14185 ENOG4105C0P Mg chelatase subunit ChlI Aba5845_14195 ENOG4108R0M Aminoglycoside Aba5845_14240 ENOG4105CHH sulfate transporter Aba5845_14285 ENOG4105C0P Mg chelatase subunit ChlI Aba5845_14290 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Aba5845_14300 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) Aba5845_14315 ENOG4105EPF Outer membrane porin Aba5845_14320 ENOG4105F0N pyrophosphate phospho-hydrolase Aba5845_14335 ENOG4105CEY Amp-dependent synthetase and ligase Aba5845_14340 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) Aba5845_14345 ENOG41079KZ Major Facilitator Superfamily Aba5845_14350 ENOG4105EN6 Membrane Aba5845_14360 ENOG4105EE5 Membrane protein terC Aba5845_14365 ENOG4108URH decarboxylase Aba5845_14380 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) Aba5845_14395 ENOG4105CCT upf0313 protein Aba5845_14415 ENOG4105CS1 NAD(P)H quinone oxidoreductase Aba5845_14425 ENOG4105C6T cysteine synthase Aba5845_14495 ENOG4105C79 DNA protecting protein DprA Aba5845_14510 ENOG4108IND Tetr family transcriptional regulator Aba5845_14515 ENOG4107RTG Major Facilitator superfamily Aba5845_14525 ENOG4108V06 Glutathione peroxidase Aba5845_14565 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) Aba5845_14590 ENOG4105FDK ABC transporter Aba5845_14595 ENOG4105FAV ABC, transporter Aba5845_14605 ENOG4105EZR dyp-type peroxidase family protein Aba5845_14615 ENOG4107R1I NAD-dependent malic enzyme Aba5845_14640 ENOG4105EUB pirin domain protein Aba5845_14660 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) Aba5845_14665 ENOG4106MP8 UPF0754 membrane protein Aba5845_14670 ENOG4108VBZ doxx family Aba5845_14675 ENOG4105DQR SNARE associated Golgi Aba5845_14690 ENOG4107QJE Chromosome Partitioning Protein Aba5845_14700 ENOG4107PSF BolA-like protein Aba5845_14720 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) Aba5845_14745 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_14770 ENOG4105CSH Transporter Aba5845_14775 ENOG4105E39 Enoyl-CoA hydratase Aba5845_14780 ENOG4105E39 Enoyl-CoA hydratase Aba5845_14785 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_14795 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase Aba5845_14800 ENOG4105C26 Dehydrogenase Aba5845_14810 ENOG4105C85 amino acid Aba5845_14815 ENOG4105C85 amino acid Aba5845_14820 ENOG4105M4H endoribonuclease L-psp Aba5845_14835 ENOG4105EW9 transcriptional regulator AsnC family Aba5845_14860 ENOG4105D3G Pseudouridine synthase Aba5845_14875 ENOG4108IG5 Transcriptional regulator Aba5845_14925 ENOG4108I0Z Aconitate hydratase Aba5845_14930 ENOG4105BZN citrate synthase Aba5845_14935 ENOG4105CR4 methylisocitrate lyase Aba5845_14940 ENOG4105DRR Transcriptional regulator, GntR family Aba5845_14950 ENOG4105CGF Aromatic amino acid aminotransferase Aba5845_14955 ENOG4105CXG d-lactate dehydrogenase Aba5845_14965 ENOG41073TP transcriptional regulator Aba5845_14970 ENOG4105DAA L-lactate Aba5845_14975 ENOG4107QKV phosphomannomutase Aba5845_14980 ENOG4105CMR udp-glucose 4-epimerase Aba5845_14990 ENOG4105C6Y Udp-glucose 6-dehydrogenase Aba5845_14995 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase Aba5845_15000 ENOG4105D3Q Sugar transferase Aba5845_15005 ENOG4108RYC glycosyltransferase Aba5845_15045 ENOG4105F0R Cytidylyltransferase Aba5845_15050 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase Aba5845_15055 ENOG4105C5E polysaccharide biosynthesis protein Aba5845_15060 ENOG4107QQG Dehydrogenase Aba5845_15065 ENOG4105DAY polysaccharide export protein Aba5845_15075 ENOG4105D75 Capsular exopolysaccharide family Aba5845_15080 ENOG4108V1T peptidylprolyl cis-trans isomerase Aba5845_15085 ENOG4108V1T peptidylprolyl cis-trans isomerase Aba5845_15090 ENOG4105CJR Integral membrane protein (MviN Aba5845_15095 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase Aba5845_15100 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase Aba5845_15140 ENOG41062JF Transcriptional regulator Aba5845_15155 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) Aba5845_15160 ENOG4105UBK short-chain dehydrogenase reductase Aba5845_15175 ENOG4107QZM n-acetylglutamate synthase Aba5845_15180 ENOG4105GVF (ABC) transporter Aba5845_15185 ENOG4105GVF (ABC) transporter Aba5845_15190 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) Aba5845_15195 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component Aba5845_15200 ENOG4108VM9 ABC, transporter Aba5845_15205 ENOG4108R86 Transcriptional regulator Aba5845_15210 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) Aba5845_15220 ENOG4105DTN riboflavin biosynthesis protein ribF Aba5845_15225 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) Aba5845_15235 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase Aba5845_15275 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) Aba5845_15330 ENOG4105CVE Lytic murein transglycosylase Aba5845_15335 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit Aba5845_15340 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) Aba5845_15355 ENOG4105DFU Cell wall formation (By similarity) Aba5845_15365 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase Aba5845_15370 ENOG4105DU1 integral membrane protein, terc Aba5845_15380 ENOG4106032 Glutathionylspermidine synthase Aba5845_15390 ENOG4107QUY Guanine deaminase Aba5845_15395 ENOG4108UGV hypoxanthine phosphoribosyltransferase Aba5845_15405 ENOG4105T95 Thiol disulfide interChange protein Aba5845_15410 ENOG4105PGM cation diffusion facilitator family transporter Aba5845_15425 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins Aba5845_15440 ENOG4105VG0 50S ribosomal protein l34 Aba5845_15450 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) Aba5845_15460 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) Aba5845_15470 ENOG4105DQR SNARE associated Golgi Aba5845_15475 ENOG4105C5H ABC transporter Aba5845_15480 ENOG4108821 RND type efflux pump Aba5845_15485 ENOG4108821 RND type efflux pump Aba5845_15490 ENOG4108821 RND type efflux pump Aba5845_15500 ENOG4105D74 hydrolase Aba5845_15505 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) Aba5845_15510 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) Aba5845_15555 ENOG4105C8J )-transporter Aba5845_15565 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B Aba5845_15590 ENOG4108W5M transcriptional regulator Aba5845_15595 ENOG4105C2W permease Aba5845_15605 ENOG4108IG5 Transcriptional regulator Aba5845_15610 ENOG4105DJY efflux transporter, rnd family, mfp subunit Aba5845_15645 ENOG4105F27 Major Facilitator Aba5845_15650 ENOG4105CV8 reductase Aba5845_15655 ENOG4105HEI LysR family (Transcriptional regulator Aba5845_15675 ENOG4105DQ4 alcohol dehydrogenase Aba5845_15680 ENOG4108R3E Dna-3-methyladenine glycosylase i Aba5845_15695 ENOG4105CEN a g-specific adenine glycosylase Aba5845_15715 ENOG4108ZZ3 UPF0260 protein Aba5845_15725 ENOG4105D1H recombination factor protein RarA Aba5845_15730 ENOG4105S64 Formate nitrite transporter Aba5845_15750 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) Aba5845_15755 ENOG4108RWI nicotinamidase Aba5845_15760 ENOG4105C09 Bile acid Aba5845_15765 ENOG4107QI1 Mate efflux family protein Aba5845_15770 ENOG4105EWC Purine nucleoside phosphorylase Aba5845_15790 ENOG4108RXX maleylacetoacetate isomerase Aba5845_15800 ENOG4105C85 amino acid Aba5845_15810 ENOG4105CKI cobalamin synthesis protein Aba5845_15820 ENOG4105CZE histidine utilization repressor Aba5845_15825 ENOG41090B9 response to stress Aba5845_15840 ENOG4105C85 amino acid Aba5845_15850 ENOG41088SP formiminoglutamate hydrolase Aba5845_15865 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) Aba5845_15870 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) Aba5845_15880 ENOG4108ZAI phosphatidylglycerophosphatase a Aba5845_15885 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) Aba5845_15900 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) Aba5845_15940 ENOG4105KHC sulfurtransferase Aba5845_15970 ENOG4105BZU Histidine kinase Aba5845_15975 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Aba5845_15990 ENOG4107QJQ Mate efflux family protein Aba5845_15995 ENOG4105CHM Aminotransferase Aba5845_16000 ENOG4106BRA Membrane Aba5845_16015 ENOG4105D9M gamma-glutamylcysteine synthetase Aba5845_16025 ENOG4105CS6 Rhs element vgr protein Aba5845_16030 ENOG4105K4H Nlp p60 protein Aba5845_16050 ENOG4105IPS esterase Aba5845_16055 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) Aba5845_16060 ENOG4105EWI Short-chain dehydrogenase reductase Sdr Aba5845_16065 ENOG4108Z2U ureidoglycolate hydrolase Aba5845_16075 ENOG41061H0 Monooxygenase Aba5845_16090 ENOG41084YZ Hydrolase Aba5845_16120 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) Aba5845_16125 ENOG4105BZU Histidine kinase Aba5845_16140 ENOG4105KUZ arsenate reductase Aba5845_16145 ENOG4105CGK Exodeoxyribonuclease III Aba5845_16165 ENOG4105D7Z glutathione synthase Aba5845_16185 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) Aba5845_16190 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) Aba5845_16195 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) Aba5845_16210 ENOG41063SB peptidase Aba5845_16215 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) Aba5845_16220 ENOG4107QSN dihydrolipoamide acetyltransferase Aba5845_16260 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) Aba5845_16275 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) Aba5845_16295 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase Aba5845_16300 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase Aba5845_16310 ENOG4105D64 Mechanosensitive ion channel Aba5845_16320 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) Aba5845_16325 ENOG4108W2Y isochorismatase Aba5845_16335 ENOG4105D5G Transposase Aba5845_16340 ENOG4105FBW Monooxygenase Aba5845_16345 ENOG4108UZX fmn reductase Aba5845_16360 ENOG4105BZU Histidine kinase Aba5845_16365 ENOG41062QD Membrane Aba5845_16370 ENOG4107QN1 sodium solute Aba5845_16380 ENOG4105C94 Transporter Aba5845_16390 ENOG4105BZU Histidine kinase Aba5845_16400 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) Aba5845_16405 ENOG4108WUH Transcriptional regulator, TetR family Aba5845_16410 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein Aba5845_16420 ENOG4105RA2 Membrane Aba5845_16425 ENOG4105DWF phosphomethylpyrimidine kinase Aba5845_16435 ENOG4107RDB Major Facilitator Aba5845_16440 ENOG4108UUM single-stranded DNA-binding protein Aba5845_16450 ENOG4108UMN azlc family Aba5845_16460 ENOG4105C85 amino acid Aba5845_16470 ENOG4108JPW Aminotransferase Aba5845_16475 ENOG4105C26 Dehydrogenase Aba5845_16485 ENOG4105CHJ isochorismatase hydrolase Aba5845_16490 ENOG4105EUB pirin domain protein Aba5845_16515 ENOG4105D94 Major Facilitator Superfamily Aba5845_16520 ENOG4106NZI LysR family Transcriptional regulator Aba5845_16540 ENOG4105CPC Aldo Keto reductase Aba5845_16545 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) Aba5845_16575 ENOG4105KVH Transcriptional regulator Aba5845_16585 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein Aba5845_16650 ENOG4105CUV Homoserine Kinase Aba5845_16665 ENOG41061CK Antibiotic biosynthesis monooxygenase Aba5845_16695 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) Aba5845_16725 ENOG4105CYC Transferase Aba5845_16735 ENOG4105E0F Histidine kinase Aba5845_16740 ENOG4105DPZ Two component transcriptional regulator (Winged helix family Aba5845_16750 ENOG4105CHH sulfate transporter Aba5845_16755 ENOG4105PDP Short chain dehydrogenase Aba5845_16765 ENOG4105C5H ABC transporter Aba5845_16850 ENOG4108IQI permease Aba5845_16875 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein Aba5845_16890 ENOG4105CJN penicillin-binding protein Aba5845_16895 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) Aba5845_16900 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) Aba5845_16915 ENOG4105DHI Methyltransferase Aba5845_16920 ENOG4108JQC penicillin-binding protein 1A Aba5845_16945 ENOG4105E4G Type IV pilus Aba5845_16965 ENOG4105CBC glutamate synthase Aba5845_16970 ENOG4105BZ8 glutamate synthase Aba5845_16980 ENOG4108V0P LemA family Aba5845_16985 ENOG4105HA9 of methanol dehydrogenase type Aba5845_17005 ENOG4108YSG O-Antigen polymerase Aba5845_17010 ENOG4108UQY Iron-storage protein Aba5845_17020 ENOG4105KME endoribonuclease L-psp Aba5845_17025 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) Aba5845_17035 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) Aba5845_17085 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) Aba5845_17100 ENOG4107IFA Lipase (EC 3.1.1.3) Aba5845_17105 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) Aba5845_17110 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) Aba5845_17135 ENOG4108JQ1 Dehydrogenase Aba5845_17140 ENOG4105CQB FAD linked oxidase domain protein Aba5845_17150 ENOG4105VRH Antibiotic biosynthesis monooxygenase Aba5845_17155 ENOG4105NF4 modulator of drug activity Aba5845_17165 ENOG4107QF7 multi-drug Aba5845_17170 ENOG4105EM2 membrane Aba5845_17175 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) Aba5845_17180 ENOG4105IPI Membrane Aba5845_17185 ENOG4107SKI cobyrinic Acid a,c-diamide synthase Aba5845_17215 ENOG4108IQI permease Aba5845_17220 ENOG4105D82 Glutamate dehydrogenase Aba5845_17225 ENOG4105C8Y Acetylornithine aminotransferase Aba5845_17235 ENOG4105C26 Dehydrogenase Aba5845_17260 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin Aba5845_17320 ENOG4105W87 Cbs domain Aba5845_17325 ENOG41067S9 phage shock protein C, PspC Aba5845_17335 ENOG4105CSU acyl-Coa dehydrogenase Aba5845_17350 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) Aba5845_17365 ENOG4105ECY inositol monophosphatase Aba5845_17370 ENOG4105C1J atp-dependent rna helicase Aba5845_17375 ENOG4105DHJ ABC, transporter Aba5845_17380 ENOG4105CY3 ABC transporter, permease Aba5845_17390 ENOG4105E3I toluene tolerance Aba5845_17400 ENOG4105D7N magnesium and cobalt transport protein CorA Aba5845_17405 ENOG4108URH decarboxylase Aba5845_17415 ENOG4105MJ2 Competence protein Aba5845_17420 ENOG4105CB5 ATP-dependent DNA helicase recG Aba5845_17440 ENOG4105C29 acyl-CoA thioesterase Aba5845_17445 ENOG4105CK2 sodium dicarboxylate symporter Aba5845_17460 ENOG4105KPV Transcriptional regulator Aba5845_17470 ENOG4105D7A ATP-binding protein Aba5845_17475 ENOG4105C28 cystathionine Aba5845_17480 ENOG41089BK Glutamine amido-transferase Aba5845_17590 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) Aba5845_17595 ENOG41067V7 50S ribosomal protein L36 Aba5845_17605 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) Aba5845_17630 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_17665 ENOG4105VKU nucleicacid-binding protein Aba5845_17670 ENOG4105DGW oligopeptidase A Aba5845_17675 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) Aba5845_17720 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase Aba5845_17725 ENOG4108K2B transcriptional regulator Aba5845_17735 ENOG4107S2Z UPF0761 membrane protein Aba5845_17740 ENOG4105CS1 NAD(P)H quinone oxidoreductase Aba5845_17770 ENOG4105C9A Phoh family Aba5845_17780 ENOG4105E4C Lytic transglycosylase catalytic Aba5845_17810 ENOG4105D6S protein involved in catabolism of external DNA Aba5845_17815 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase Aba5845_17860 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_17865 ENOG4108RZE Tetr family transcriptional regulator Aba5845_17880 ENOG4107QX3 carboxylase Aba5845_17885 ENOG4105C1G acyl-Coa dehydrogenase Aba5845_17905 ENOG4105KB2 stringent starvation protein b Aba5845_17910 ENOG4107MKT Stringent starvation protein a Aba5845_17915 ENOG4108UJD 30S ribosomal protein S9 Aba5845_17925 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) Aba5845_17930 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) Aba5845_17935 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) Aba5845_17955 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) Aba5845_17965 ENOG4107RZC phospholipase d Aba5845_17975 ENOG4105UYK outer membrane protein a Aba5845_17980 ENOG4108KHX Diguanylate cyclase Aba5845_18015 ENOG4107QN2 dihydrolipoyl dehydrogenase Aba5845_18025 ENOG4107QPB Beta-lactamase domain protein Aba5845_18030 ENOG4107U2T alpha beta Aba5845_18040 ENOG4105NAU thioesterase Superfamily protein Aba5845_18070 ENOG4105K9H YciI-like protein Aba5845_18080 ENOG4105DB7 PHP domain protein Aba5845_18085 ENOG4105FFC UPF0187 protein Aba5845_18095 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase Aba5845_18100 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) Aba5845_18105 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) Aba5845_18110 ENOG4105VIE preprotein translocase, subunit YajC Aba5845_18160 ENOG4105BZU Histidine kinase Aba5845_18165 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) Aba5845_18170 ENOG4105CM2 brancheD-chain amino acid aminotransferase Aba5845_18185 ENOG4107BJW polysaccharide deacetylase Aba5845_18195 ENOG4108PQP glycosyl transferase group 1 Aba5845_18235 ENOG4105UGU tonB-dependent Receptor Aba5845_18255 ENOG4108VY7 phosphate-starvation-inducible protein PsiE Aba5845_18260 ENOG4108K3A Glutathione S-transferase Aba5845_18265 ENOG4108R4R Iron-regulated virulence regulatory protein Aba5845_18270 ENOG4105CSU acyl-Coa dehydrogenase Aba5845_18275 ENOG4105CSU acyl-Coa dehydrogenase Aba5845_18285 ENOG4105EB3 Histidine kinase Aba5845_18290 ENOG4105E3W Two component transcriptional regulator (Winged helix family Aba5845_18295 ENOG4105CNG UPF0061 protein Aba5845_18315 ENOG4108WBT adenosyltransferase Aba5845_18330 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) Aba5845_18365 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase Aba5845_18385 ENOG4105D3R alkyl hydroperoxide reductase Aba5845_18400 ENOG4105CSH Transporter Aba5845_18405 ENOG4108UT2 hemolysin iii Aba5845_18435 ENOG4105CHU acetyl-coa acetyltransferase Aba5845_18440 ENOG4108R6W Transcriptional regulator, ARAC family Aba5845_18450 ENOG4105TW1 Carbohydrate-selective porin OprB Aba5845_18455 ENOG4105DZG Dehydrogenase Aba5845_18460 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) Aba5845_18470 ENOG410814C multidrug resistance protein Aba5845_18480 ENOG4105CHU acetyl-coa acetyltransferase Aba5845_18490 ENOG4108WHA ompa motb domain protein Aba5845_18500 ENOG4105E0Y RtcB Protein Aba5845_18505 ENOG4108IQI permease Aba5845_18515 ENOG4105C2W permease Aba5845_18535 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) Aba5845_18545 ENOG4108VX5 3-methyladenine DNA glycosylase Aba5845_18550 ENOG4105CHB tonB-dependent Receptor Aba5845_18565 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase Aba5845_18570 ENOG4108N2Y auxin Efflux Aba5845_18580 ENOG4105T95 Thiol disulfide interChange protein Aba5845_18585 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) Aba5845_18595 ENOG4105K78 MarR family Transcriptional regulator Aba5845_18600 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA Aba5845_18605 ENOG4105KWI UPF0339 protein Aba5845_18630 ENOG4108UNF response regulator Aba5845_18635 ENOG4105M3Z response regulator Aba5845_18640 ENOG4108ZGA chew protein Aba5845_18645 ENOG4105C8Q Methyl-accepting chemotaxis Aba5845_18650 ENOG4105CBS Chea signal transduction histidine kinase Aba5845_18665 ENOG4106HKS Entericidin EcnA/B family Aba5845_18675 ENOG4105WD1 Membrane Aba5845_18680 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein Aba5845_18720 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) Aba5845_18730 ENOG4105EM2 membrane Aba5845_18735 ENOG4105C2C drug resistance transporter, Bcr CflA Aba5845_18755 ENOG4105BZG amino acid carrier protein Aba5845_18760 ENOG4105D78 K07001 NTE family protein Aba5845_18765 ENOG4105C7B Threonine dehydratase Aba5845_18800 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) Aba5845_18810 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) Aba5845_18815 ENOG4105DFF Rod shape-determining protein mreb Aba5845_18820 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) Aba5845_18825 ENOG4105VQ7 Rod shape-determining protein MreD Aba5845_18830 ENOG4108Z03 MAF-like protein Aba5845_18835 ENOG4105C03 ribonuclease Aba5845_18845 ENOG4105D8T Acyltransferase Aba5845_18855 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein Aba5845_18865 ENOG4108X0B nad(p)h dehydrogenase (quinone) Aba5845_18890 ENOG4105CF7 AraC family transcriptional regulator Aba5845_18910 ENOG4105C85 amino acid Aba5845_18915 ENOG4105C7F AcnD-accessory protein PrpF Aba5845_18920 ENOG4105CTB Polyprenyl synthetase Aba5845_18925 ENOG4105MSB protein, conserved in bacteria Aba5845_18940 ENOG4105D78 K07001 NTE family protein Aba5845_18960 ENOG4105DIJ Phosphoethanolamine transferase Aba5845_18965 ENOG4105XJC Two component transcriptional regulator (Winged helix family Aba5845_18970 ENOG4105DHQ Histidine kinase Aba5845_18990 ENOG4108M0I Transcriptional regulator Aba5845_19010 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) Aba5845_19030 ENOG4105K8R UPF0145 protein Aba5845_19035 ENOG4105K8R UPF0145 protein Aba5845_19040 ENOG4105ENJ RND efflux system, outer membrane lipoprotein Aba5845_19045 ENOG4105BZS acriflavin resistance protein Aba5845_19050 ENOG4105C1P efflux transporter, rnd family, mfp subunit Aba5845_19055 ENOG410841Q phosphoesterase PA-phosphatase related protein Aba5845_19085 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) Aba5845_19100 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) Aba5845_19105 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) Aba5845_19110 ENOG4105KVH Transcriptional regulator Aba5845_19120 ENOG4105CUB amino acid Aba5845_19135 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) Aba5845_19140 ENOG41084BA UPF0250 protein Aba5845_19145 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Aba5845_19180 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit Aba5845_19185 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein Aba5845_19195 ENOG4105E33 succinate dehydrogenase Aba5845_19210 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 Aba5845_19215 ENOG4105C7S Dehydrogenase Aba5845_19220 ENOG4107QN2 dihydrolipoyl dehydrogenase Aba5845_19230 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha Aba5845_19240 ENOG4105CKW Inner membrane protein yedI Aba5845_19245 ENOG4105CGZ zinc metallopeptidase Aba5845_19250 ENOG4105EEQ Na H antiporter Aba5845_19285 ENOG4108HWY Beta-lactamase