locus-tag	class	description
RU84_00010	COG0592	DNA-directed DNA polymerase activity
RU84_00020	COG0187	DNA topoisomerase II activity
RU84_00030	COG0586	Pfam SNARE associated Golgi protein
RU84_00035	COG0488	(ABC) transporter
RU84_00060	COG0596	Alpha beta hydrolase
RU84_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RU84_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RU84_00105	COG0625	glutathione transferase activity
RU84_00115	COG0733	neurotransmitter:sodium symporter activity
RU84_00150	COG0583	DNA-binding transcription factor activity
RU84_00155	COG2233	PERMEase
RU84_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RU84_00205	COG2814	Major facilitator Superfamily
RU84_00210	COG0656	L-ascorbic acid biosynthetic process
RU84_00215	COG0583	DNA-binding transcription factor activity
RU84_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RU84_00230	COG1064	alcohol dehydrogenase
RU84_00235	COG2818	Glycosylase
RU84_00250	COG1194	a g-specific adenine glycosylase
RU84_00270	COG2983	Belongs to the UPF0260 family
RU84_00275	COG2133	pyrroloquinoline quinone binding
RU84_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RU84_00285	COG2116	formate transmembrane transporter activity
RU84_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RU84_00310	COG1335	isochorismatase
RU84_00315	COG0385	Bile acid
RU84_00320	COG0534	Mate efflux family protein
RU84_00325	COG1683	Conserved Protein
RU84_00345	COG0625	glutathione transferase activity
RU84_00355	COG1113	amino acid transport
RU84_00365	COG0523	cobalamin synthesis protein
RU84_00375	COG2188	Transcriptional regulator
RU84_00405	COG0010	Belongs to the arginase family
RU84_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RU84_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RU84_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RU84_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RU84_00540	COG0534	Mate efflux family protein
RU84_00545	COG0436	Aminotransferase
RU84_00550	COG2733	membrane
RU84_00565	COG2918	glutathione biosynthetic process
RU84_00575	COG3501	Rhs element vgr protein
RU84_00580	COG3409	Peptidoglycan-binding domain 1 protein
RU84_00580	COG5632	N-Acetylmuramoyl-L-alanine amidase
RU84_00580	COG1388	LysM domain
RU84_00610	COG3150	esterase
RU84_00620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
RU84_00630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RU84_00640	COG2233	PERMEase
RU84_00680	COG3706	GGDEF domain
RU84_00695	COG1393	Belongs to the ArsC family
RU84_00700	COG0708	Exodeoxyribonuclease III
RU84_00720	COG0189	ligase activity
RU84_00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RU84_00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RU84_00765	COG4942	peptidase
RU84_00775	COG0508	dehydrogenase complex catalyzes the overall conversion of
RU84_00785	COG2119	membrane
RU84_00790	COG4774	siderophore transport
RU84_00795	COG0426	domain, Protein
RU84_00795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RU84_00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RU84_00840	COG1902	pentaerythritol trinitrate reductase activity
RU84_00845	COG1519	Transferase
RU84_00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RU84_00855	COG0668	transmembrane transport
RU84_00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RU84_00870	COG1335	isochorismatase
RU84_00875	COG1522	sequence-specific DNA binding
RU84_00900	COG2205	protein histidine kinase activity
RU84_00900	COG0784	Response regulator, receiver
RU84_00900	COG2198	Histidine kinase
RU84_00905	COG3162	membrane
RU84_00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RU84_00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RU84_00930	COG3706	GGDEF domain
RU84_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RU84_00940	COG1309	transcriptional regulator
RU84_00960	COG0351	phosphomethylpyrimidine kinase
RU84_00960	COG0352	thiamine-phosphate diphosphorylase activity
RU84_00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RU84_00970	COG2814	Major facilitator Superfamily
RU84_00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RU84_00995	COG1113	amino acid transport
RU84_01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RU84_01010	COG1012	belongs to the aldehyde dehydrogenase family
RU84_01020	COG1335	isochorismatase
RU84_01050	COG2814	Major facilitator Superfamily
RU84_01055	COG0583	DNA-binding transcription factor activity
RU84_01075	COG0667	Aldo Keto reductase
RU84_01095	COG2826	transposase and inactivated derivatives, IS30 family
RU84_01110	COG1733	regulation of RNA biosynthetic process
RU84_01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
RU84_01175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RU84_01215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RU84_01245	COG0427	acetyl-CoA hydrolase
RU84_01255	COG0745	RESPONSE REGULATOR receiver
RU84_01265	COG0659	secondary active sulfate transmembrane transporter activity
RU84_01270	COG4221	oxidoreductase activity
RU84_01280	COG0488	(ABC) transporter
RU84_01360	COG0833	amino acid
RU84_01405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RU84_01410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RU84_01425	COG2226	methyltransferase
RU84_01475	COG0070	glutamate synthase
RU84_01475	COG0067	glutamate synthase
RU84_01475	COG0069	glutamate synthase activity
RU84_01480	COG0493	'glutamate synthase
RU84_01490	COG1704	LemA family
RU84_01495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RU84_01515	COG3307	-O-antigen
RU84_01535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RU84_01545	COG0194	GDP metabolic process
RU84_01595	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RU84_01615	COG5380	lipid catabolic process
RU84_01620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RU84_01645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RU84_01650	COG0277	FAD linked oxidase domain protein
RU84_01660	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RU84_01665	COG2249	NAD(P)H dehydrogenase (quinone) activity
RU84_01680	COG1289	transmembrane transporter activity
RU84_01690	COG0628	permease
RU84_01695	COG1192	Involved in chromosome partitioning
RU84_01725	COG0833	amino acid
RU84_01730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RU84_01735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RU84_01745	COG1012	belongs to the aldehyde dehydrogenase family
RU84_01785	COG0583	DNA-binding transcription factor activity
RU84_01835	COG0517	IMP dehydrogenase activity
RU84_01840	COG1983	PspC domain protein
RU84_01850	COG1960	acyl-CoA dehydrogenase activity
RU84_01865	COG0408	coproporphyrinogen oxidase activity
RU84_01885	COG0513	Belongs to the DEAD box helicase family
RU84_01895	COG1127	ABC transporter
RU84_01900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RU84_01910	COG2854	intermembrane phospholipid transfer
RU84_01920	COG0598	Magnesium transport protein CorA
RU84_01930	COG0494	nUDIX hydrolase
RU84_01935	COG1040	competence protein
RU84_01940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RU84_01960	COG1946	Acyl-CoA thioesterase
RU84_01965	COG1301	dicarboxylic acid transport
RU84_01980	COG1959	2 iron, 2 sulfur cluster binding
RU84_01985	COG1017	nitric oxide dioxygenase activity
RU84_01985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RU84_01990	COG0433	COG0433 Predicted ATPase
RU84_01995	COG0626	cystathionine gamma-synthase activity
RU84_02115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RU84_02125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RU84_02150	COG1960	acyl-CoA dehydrogenase activity
RU84_02155	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RU84_02185	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
RU84_02190	COG0339	signal peptide processing
RU84_02195	COG0557	exoribonuclease II activity
RU84_02240	COG0179	Fumarylacetoacetate (FAA) hydrolase
RU84_02245	COG2169	Transcriptional regulator
RU84_02250	COG0697	spore germination
RU84_02255	COG1295	ribonuclease BN
RU84_02290	COG1702	phosphate starvation-inducible protein PhoH
RU84_02300	COG0741	lytic transglycosylase activity
RU84_02300	COG1196	nuclear chromosome segregation
RU84_02300	COG0739	heme binding
RU84_02330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RU84_02335	COG1183	phosphatidylcholine synthase activity
RU84_02380	COG1960	acyl-CoA dehydrogenase activity
RU84_02385	COG1309	transcriptional regulator
RU84_02400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RU84_02405	COG1960	acyl-CoA dehydrogenase activity
RU84_02435	COG2826	transposase and inactivated derivatives, IS30 family
RU84_02440	COG2015	COG2015, Alkyl sulfatase and related hydrolases
RU84_02470	COG2969	positive regulation of protein catabolic process
RU84_02480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RU84_02495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RU84_02500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RU84_02520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RU84_02530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RU84_02535	COG1408	metallophosphoesterase
RU84_02545	COG2199	diguanylate cyclase activity
RU84_02590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RU84_02590	COG3453	Protein conserved in bacteria
RU84_02605	COG1607	acyl-coa hydrolase
RU84_02635	COG2350	Protein conserved in bacteria
RU84_02645	COG0613	PHP domain protein
RU84_02650	COG3781	membrane
RU84_02660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RU84_02665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RU84_02675	COG1862	Preprotein translocase
RU84_02725	COG0629	single-stranded DNA binding
RU84_02915	COG4695	Portal protein
RU84_02920	COG2205	protein histidine kinase activity
RU84_02925	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RU84_02940	COG0726	polysaccharide deacetylase
RU84_02945	COG0438	transferase activity, transferring glycosyl groups
RU84_02960	COG1091	dTDP-4-dehydrorhamnose reductase activity
RU84_02975	COG1215	transferase activity, transferring glycosyl groups
RU84_03025	COG1960	acyl-CoA dehydrogenase activity
RU84_03030	COG1960	acyl-CoA dehydrogenase activity
RU84_03040	COG2205	protein histidine kinase activity
RU84_03045	COG0745	RESPONSE REGULATOR receiver
RU84_03050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RU84_03070	COG2096	Adenosyltransferase
RU84_03085	COG0133	tryptophan synthase activity
RU84_03120	COG0285	dihydrofolate synthase activity
RU84_03140	COG0450	alkyl hydroperoxide reductase
RU84_03155	COG0477	Major facilitator Superfamily
RU84_03160	COG1272	protein, Hemolysin III
RU84_03190	COG0183	Belongs to the thiolase family
RU84_03195	COG2207	Transcriptional regulator
RU84_03215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RU84_03235	COG0183	Belongs to the thiolase family
RU84_03245	COG2885	chlorophyll binding
RU84_03245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RU84_03255	COG1690	Belongs to the RtcB family
RU84_03260	COG0833	amino acid
RU84_03270	COG2233	PERMEase
RU84_03300	COG2094	Belongs to the DNA glycosylase MPG family
RU84_03305	COG4772	TonB-dependent receptor
RU84_03310	COG1902	pentaerythritol trinitrate reductase activity
RU84_03325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RU84_03330	COG0354	folic acid binding
RU84_03340	COG3189	MarR family transcriptional regulator
RU84_03345	COG2824	Alkylphosphonate utilization operon protein PhnA
RU84_03350	COG3422	double-strand break repair
RU84_03390	COG0840	transmembrane signaling receptor activity
RU84_03405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RU84_03420	COG5510	response to toxic substance
RU84_03430	COG2832	Protein of unknown function (DUF454)
RU84_03435	COG1376	ErfK ybiS ycfS ynhG family protein
RU84_03485	COG1289	transmembrane transporter activity
RU84_03490	COG2814	Major facilitator Superfamily
RU84_03505	COG1115	amino acid carrier protein
RU84_03510	COG1752	Esterase of the alpha-beta hydrolase superfamily
RU84_03515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RU84_03520	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
RU84_03525	COG3590	peptidase
RU84_03550	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RU84_03560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RU84_03565	COG1077	Cell shape determining protein MreB Mrl
RU84_03570	COG1792	Involved in formation and maintenance of cell shape
RU84_03575	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RU84_03580	COG0424	maF-like protein
RU84_03585	COG1530	ribonuclease E activity
RU84_03595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RU84_03615	COG2249	NAD(P)H dehydrogenase (quinone) activity
RU84_03640	COG2207	Transcriptional regulator
RU84_03660	COG1113	amino acid transport
RU84_03665	COG2828	Protein conserved in bacteria
RU84_03670	COG0142	geranyltranstransferase activity
RU84_03675	COG2315	Protein conserved in bacteria
RU84_03690	COG1752	Esterase of the alpha-beta hydrolase superfamily
RU84_03710	COG2194	sulfuric ester hydrolase activity
RU84_03715	COG0745	RESPONSE REGULATOR receiver
RU84_03720	COG0642	Histidine kinase
RU84_03730	COG0004	ammonium transporteR
RU84_03735	COG0583	DNA-binding transcription factor activity
RU84_03755	COG0525	valine-tRNA ligase activity
RU84_03765	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_03775	COG0393	Putative heavy-metal-binding
RU84_03780	COG0393	Putative heavy-metal-binding
RU84_03785	COG1538	Outer membrane efflux protein
RU84_03795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RU84_03800	COG0671	phosphoesterase, PA-phosphatase related
RU84_03830	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RU84_03845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RU84_03845	COG1648	precorrin-2 dehydrogenase activity
RU84_03850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RU84_03855	COG1733	regulation of RNA biosynthetic process
RU84_03865	COG0531	amino acid
RU84_03880	COG0321	lipoyl(octanoyl) transferase activity
RU84_03885	COG2921	Belongs to the UPF0250 family
RU84_03920	COG2009	succinate dehydrogenase
RU84_03925	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RU84_03930	COG1053	succinate dehydrogenase
RU84_03935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RU84_03950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RU84_03970	COG2354	Protein conserved in bacteria
RU84_03975	COG2321	neutral zinc metallopeptidase
RU84_03995	COG2843	Capsule synthesis protein
RU84_04010	COG0589	response to stress
RU84_04020	COG0251	oxidation-reduction process
RU84_04025	COG1309	transcriptional regulator
RU84_04040	COG0505	Belongs to the CarA family
RU84_04065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RU84_04070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RU84_04120	COG0477	Major facilitator Superfamily
RU84_04125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RU84_04145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RU84_04170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RU84_04175	COG0584	glycerophosphoryl diester phosphodiesterase
RU84_04195	COG0741	lytic transglycosylase activity
RU84_04215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RU84_04230	COG2826	transposase and inactivated derivatives, IS30 family
RU84_04235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RU84_04255	COG3811	Belongs to the UPF0386 family
RU84_04275	COG0778	Nitroreductase
RU84_04290	COG1929	Belongs to the glycerate kinase type-1 family
RU84_04295	COG0243	molybdopterin cofactor binding
RU84_04300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RU84_04305	COG3339	Conserved Protein
RU84_04315	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
RU84_04330	COG1113	amino acid transport
RU84_04340	COG0019	diaminopimelate decarboxylase activity
RU84_04350	COG1280	lysine exporter protein (LysE YggA)
RU84_04355	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RU84_04385	COG0463	Glycosyl transferase, family 2
RU84_04405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RU84_04435	COG4591	ABC-type transport system involved in lipoprotein release permease component
RU84_04440	COG1136	(ABC) transporter
RU84_04455	COG2333	competence protein COMEC
RU84_04455	COG0658	competence protein
RU84_04465	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RU84_04465	COG0616	signal peptide processing
RU84_04470	COG0596	Alpha beta hydrolase
RU84_04475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RU84_04485	COG0628	permease
RU84_04505	COG2826	transposase and inactivated derivatives, IS30 family
RU84_04530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RU84_04550	COG0823	Involved in the tonB-independent uptake of proteins
RU84_04570	COG0824	Thioesterase
RU84_04575	COG1473	amidohydrolase
RU84_04595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RU84_04595	COG0047	phosphoribosylformylglycinamidine synthase activity
RU84_04600	COG2814	Major facilitator Superfamily
RU84_04610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RU84_04615	COG1024	Enoyl-CoA hydratase
RU84_04620	COG1051	belongs to the nudix hydrolase family
RU84_04620	COG1056	cytidyltransferase-related domain
RU84_04630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RU84_04645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RU84_04660	COG4625	pathogenesis
RU84_04665	COG0583	DNA-binding transcription factor activity
RU84_04670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RU84_04675	COG4208	sulfate ABC transporter
RU84_04680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RU84_04690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RU84_04695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RU84_04700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RU84_04720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RU84_04735	COG0681	Belongs to the peptidase S26 family
RU84_04750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RU84_04760	COG1381	Involved in DNA repair and RecF pathway recombination
RU84_04765	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RU84_04775	COG4221	oxidoreductase activity
RU84_04800	COG0443	Heat shock 70 kDa protein
RU84_04830	COG0556	nucleotide-excision repair
RU84_04885	COG2070	2-Nitropropane dioxygenase
RU84_04915	COG1215	transferase activity, transferring glycosyl groups
RU84_04930	COG0415	Belongs to the DNA photolyase family
RU84_04940	COG1252	NADH dehydrogenase
RU84_04945	COG1686	Belongs to the peptidase S11 family
RU84_04960	COG1187	pseudouridine synthase activity
RU84_04980	COG0477	Major facilitator Superfamily
RU84_04985	COG0583	DNA-binding transcription factor activity
RU84_05000	COG0612	Peptidase, M16
RU84_05025	COG0352	thiamine-phosphate diphosphorylase activity
RU84_05060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RU84_05070	COG2249	NAD(P)H dehydrogenase (quinone) activity
RU84_05085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RU84_05090	COG0076	glutamate decarboxylase activity
RU84_05100	COG1522	sequence-specific DNA binding
RU84_05105	COG3961	Belongs to the TPP enzyme family
RU84_05110	COG1113	amino acid transport
RU84_05115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RU84_05120	COG0573	inorganic phosphate transmembrane transporter activity
RU84_05130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RU84_05135	COG0616	signal peptide processing
RU84_05170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RU84_05175	COG1686	Belongs to the peptidase S11 family
RU84_05200	COG0583	DNA-binding transcription factor activity
RU84_05205	COG1067	ATP-dependent peptidase activity
RU84_05230	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RU84_05250	COG1966	Carbon starvation protein
RU84_05255	COG2879	small protein
RU84_05265	COG2130	NADP-dependent
RU84_05290	COG1741	Belongs to the pirin family
RU84_05300	COG2964	Protein conserved in bacteria
RU84_05315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RU84_05320	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RU84_05325	COG4605	iron ion homeostasis
RU84_05330	COG4604	ABC transporter, ATP-binding protein
RU84_05335	COG4607	ABC-type enterochelin transport system periplasmic component
RU84_05340	COG4774	siderophore transport
RU84_05350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RU84_05360	COG3433	isochorismatase activity
RU84_05360	COG1535	isochorismatase
RU84_05375	COG1132	(ABC) transporter
RU84_05380	COG5265	(ABC) transporter
RU84_05385	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
RU84_05395	COG1169	isochorismate synthase
RU84_05410	COG3739	integral membrane protein
RU84_05440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RU84_05470	COG0308	aminopeptidase N
RU84_05475	COG0512	Glutamine amidotransferase of anthranilate synthase
RU84_05485	COG3104	oligopeptide transport
RU84_05500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RU84_05535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RU84_05540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RU84_05545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RU84_05565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RU84_05570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RU84_05575	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RU84_05590	COG1960	acyl-CoA dehydrogenase activity
RU84_05595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RU84_05600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RU84_05615	COG2223	nitrite transmembrane transporter activity
RU84_05625	COG0024	Methionine aminopeptidase
RU84_05630	COG0052	Belongs to the universal ribosomal protein uS2 family
RU84_05645	COG2207	Transcriptional regulator
RU84_05670	COG2951	lytic endotransglycosylase activity
RU84_05675	COG0772	Belongs to the SEDS family
RU84_05690	COG0842	Transport permease protein
RU84_05695	COG1131	(ABC) transporter
RU84_05725	COG1538	Outer membrane efflux protein
RU84_05735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RU84_05750	COG4215	(ABC) transporter
RU84_05755	COG4160	amino acid transport
RU84_05760	COG4598	ABC transporter
RU84_05770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RU84_05780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RU84_05795	COG1720	tRNA m6t6A37 methyltransferase activity
RU84_05815	COG0745	RESPONSE REGULATOR receiver
RU84_05820	COG0642	Histidine kinase
RU84_05830	COG0494	nUDIX hydrolase
RU84_05840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RU84_05845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RU84_05850	COG3139	Protein of unknown function (DUF1315)
RU84_05855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RU84_05860	COG1301	dicarboxylic acid transport
RU84_05865	COG1960	acyl-CoA dehydrogenase activity
RU84_05870	COG2819	hydrolase of the alpha beta superfamily
RU84_05880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RU84_05890	COG2195	Cleaves the N-terminal amino acid of tripeptides
RU84_05895	COG1234	tRNA 3'-trailer cleavage
RU84_05925	COG2363	Small membrane protein
RU84_05945	COG0513	Belongs to the DEAD box helicase family
RU84_05955	COG0778	Nitroreductase
RU84_05985	COG1286	toxin biosynthetic process
RU84_06010	COG4783	chaperone-mediated protein folding
RU84_06015	COG1610	YqeY-like protein
RU84_06020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RU84_06070	COG2831	hemolysin activation secretion protein
RU84_06165	COG3111	PFAM Bacterial OB fold (BOF) protein
RU84_06190	COG3243	poly(R)-hydroxyalkanoic acid synthase
RU84_06195	COG0786	glutamate:sodium symporter activity
RU84_06205	COG2186	Transcriptional regulator
RU84_06260	COG0477	Major facilitator Superfamily
RU84_06285	COG2985	domain, Protein
RU84_06300	COG2995	paraquat-inducible protein a
RU84_06305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RU84_06305	COG3008	intermembrane lipid transfer
RU84_06315	COG2351	hydroxyisourate hydrolase activity
RU84_06355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RU84_06365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RU84_06370	COG0642	Histidine kinase
RU84_06375	COG0745	RESPONSE REGULATOR receiver
RU84_06395	COG1794	racemase activity, acting on amino acids and derivatives
RU84_06435	COG1301	dicarboxylic acid transport
RU84_06445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RU84_06450	COG2011	ABC-type metal ion transport system permease component
RU84_06455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RU84_06460	COG1464	Belongs to the NlpA lipoprotein family
RU84_06465	COG0151	Belongs to the GarS family
RU84_06470	COG0138	bifunctional purine biosynthesis protein purh
RU84_06475	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
RU84_06505	COG2308	Evidence 4 Homologs of previously reported genes of
RU84_06515	COG1305	Transglutaminase-like
RU84_06525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RU84_06530	COG0305	Participates in initiation and elongation during chromosome replication
RU84_06555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RU84_06565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RU84_06570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RU84_06595	COG1649	PFAM Uncharacterised BCR, COG1649
RU84_06595	COG0726	polysaccharide deacetylase
RU84_06600	COG1215	transferase activity, transferring glycosyl groups
RU84_06605	COG3658	cytochrome
RU84_06615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RU84_06630	COG0583	DNA-binding transcription factor activity
RU84_06660	COG1960	acyl-CoA dehydrogenase activity
RU84_06665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RU84_06670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RU84_06695	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RU84_06700	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RU84_06710	COG2205	protein histidine kinase activity
RU84_06715	COG0745	RESPONSE REGULATOR receiver
RU84_06720	COG0174	glutamine synthetase
RU84_06740	COG0729	surface antigen
RU84_06765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RU84_06770	COG2814	Major facilitator Superfamily
RU84_06785	COG0583	DNA-binding transcription factor activity
RU84_06800	COG1187	pseudouridine synthase activity
RU84_06820	COG0802	atpase or kinase
RU84_06825	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RU84_06835	COG1923	regulation of RNA biosynthetic process
RU84_06840	COG0697	spore germination
RU84_06865	COG0519	Catalyzes the synthesis of GMP from XMP
RU84_06865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RU84_06870	COG4302	ethanolamine ammonia-lyase activity
RU84_06875	COG4303	Ethanolamine ammonia lyase large subunit
RU84_06880	COG0531	amino acid
RU84_06900	COG1454	alcohol dehydrogenase
RU84_06905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RU84_06930	COG0308	aminopeptidase N
RU84_06970	COG1605	Chorismate mutase
RU84_06995	COG1309	transcriptional regulator
RU84_07005	COG0668	transmembrane transport
RU84_07035	COG4773	Receptor
RU84_07060	COG0488	(ABC) transporter
RU84_07065	COG0589	response to stress
RU84_07085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RU84_07095	COG3135	benzoate transporter
RU84_07100	COG1522	sequence-specific DNA binding
RU84_07110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RU84_07115	COG0583	DNA-binding transcription factor activity
RU84_07125	COG0183	Belongs to the thiolase family
RU84_07165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RU84_07175	COG0824	Thioesterase
RU84_07180	COG1454	alcohol dehydrogenase
RU84_07190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RU84_07220	COG0069	glutamate synthase activity
RU84_07240	COG2826	transposase and inactivated derivatives, IS30 family
RU84_07250	COG2814	Major facilitator Superfamily
RU84_07265	COG0511	ligase activity, forming carbon-carbon bonds
RU84_07280	COG1116	anion transmembrane transporter activity
RU84_07280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RU84_07285	COG0745	RESPONSE REGULATOR receiver
RU84_07295	COG2146	nitrite reductase [NAD(P)H] activity
RU84_07295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RU84_07300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RU84_07305	COG0243	molybdopterin cofactor binding
RU84_07315	COG0243	molybdopterin cofactor binding
RU84_07320	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RU84_07335	COG0315	cyclic pyranopterin monophosphate synthase activity
RU84_07335	COG0521	Mo-molybdopterin cofactor biosynthetic process
RU84_07340	COG0303	'Molybdopterin
RU84_07350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RU84_07355	COG0697	spore germination
RU84_07375	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
RU84_07380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RU84_07435	COG2204	response regulator
RU84_07440	COG3852	Histidine kinase
RU84_07460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RU84_07465	COG0575	Belongs to the CDS family
RU84_07480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RU84_07500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RU84_07515	COG2137	regulation of response to DNA damage stimulus
RU84_07525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RU84_07530	COG1011	Hydrolase
RU84_07555	COG1522	sequence-specific DNA binding
RU84_07565	COG1113	amino acid transport
RU84_07580	COG0659	secondary active sulfate transmembrane transporter activity
RU84_07585	COG2135	peptidase activity
RU84_07600	COG3300	MHYT domain
RU84_07600	COG5001	Diguanylate cyclase
RU84_07620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RU84_07620	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
RU84_07620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RU84_07625	COG1105	Belongs to the carbohydrate kinase PfkB family
RU84_07630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RU84_07630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RU84_07660	COG0024	Methionine aminopeptidase
RU84_07665	COG0583	DNA-binding transcription factor activity
RU84_07675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RU84_07680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RU84_07685	COG0516	GMP reductase activity
RU84_07685	COG0517	IMP dehydrogenase activity
RU84_07710	COG0552	protein localization to endoplasmic reticulum
RU84_07720	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
RU84_07730	COG4890	Cyd operon protein YbgT
RU84_07735	COG1294	oxidase, subunit
RU84_07750	COG1585	Membrane protein implicated in regulation of membrane protease activity
RU84_07760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RU84_07765	COG4774	siderophore transport
RU84_07780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RU84_07785	COG0569	domain protein
RU84_07790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RU84_07820	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RU84_07825	COG0542	response to heat
RU84_07835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RU84_07850	COG0446	pyridine nucleotide-disulphide oxidoreductase
RU84_07850	COG1902	pentaerythritol trinitrate reductase activity
RU84_07895	COG2323	membrane
RU84_07900	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RU84_07910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RU84_07915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RU84_07920	COG0183	Belongs to the thiolase family
RU84_07925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RU84_07930	COG0596	Alpha beta hydrolase
RU84_07935	COG2271	Major facilitator Superfamily
RU84_07940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RU84_07945	COG3485	protocatechuate 3,4-dioxygenase
RU84_07950	COG3485	protocatechuate 3,4-dioxygenase
RU84_07955	COG0710	3-dehydroquinate dehydratase activity
RU84_07960	COG3420	alginic acid biosynthetic process
RU84_07965	COG3659	wide pore channel activity
RU84_07970	COG4993	Dehydrogenase
RU84_07980	COG2391	methyltransferase activity
RU84_07995	COG1414	Transcriptional regulator
RU84_08000	COG0583	DNA-binding transcription factor activity
RU84_08005	COG1960	acyl-CoA dehydrogenase activity
RU84_08030	COG2814	Major facilitator Superfamily
RU84_08040	COG0154	amidase activity
RU84_08060	COG4638	Rieske (2fe-2S)
RU84_08070	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_08080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RU84_08090	COG3733	amine oxidase
RU84_08100	COG1012	belongs to the aldehyde dehydrogenase family
RU84_08105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RU84_08110	COG0183	Belongs to the thiolase family
RU84_08115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RU84_08120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RU84_08130	COG4829	muconolactone delta-isomerase
RU84_08135	COG4948	Mandelate Racemase Muconate Lactonizing
RU84_08140	COG0583	DNA-binding transcription factor activity
RU84_08150	COG2186	Transcriptional regulator
RU84_08170	COG1012	belongs to the aldehyde dehydrogenase family
RU84_08185	COG1902	pentaerythritol trinitrate reductase activity
RU84_08185	COG0446	pyridine nucleotide-disulphide oxidoreductase
RU84_08200	COG0789	Transcriptional regulator
RU84_08230	COG1309	transcriptional regulator
RU84_08235	COG0583	DNA-binding transcription factor activity
RU84_08240	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_08245	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_08250	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_08260	COG1960	acyl-CoA dehydrogenase activity
RU84_08270	COG0318	PFAM AMP-dependent synthetase and ligase
RU84_08315	COG2826	transposase and inactivated derivatives, IS30 family
RU84_08320	COG2826	transposase and inactivated derivatives, IS30 family
RU84_08355	COG0583	DNA-binding transcription factor activity
RU84_08375	COG1566	PFAM secretion protein HlyD family protein
RU84_08390	COG1012	belongs to the aldehyde dehydrogenase family
RU84_08395	COG0129	dihydroxy-acid dehydratase activity
RU84_08405	COG0583	DNA-binding transcription factor activity
RU84_08410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RU84_08420	COG2084	Dehydrogenase
RU84_08425	COG2207	Transcriptional regulator
RU84_08430	COG1064	alcohol dehydrogenase
RU84_08445	COG1120	ATPase activity
RU84_08465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RU84_08515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RU84_08555	COG1073	alpha beta
RU84_08565	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_08580	COG2207	Transcriptional regulator
RU84_08590	COG2205	protein histidine kinase activity
RU84_08595	COG0745	RESPONSE REGULATOR receiver
RU84_08600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RU84_08605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RU84_08620	COG0583	DNA-binding transcription factor activity
RU84_08635	COG2031	fatty acid transporter
RU84_08640	COG0183	Belongs to the thiolase family
RU84_08645	COG0583	DNA-binding transcription factor activity
RU84_08650	COG0583	DNA-binding transcription factor activity
RU84_08665	COG1027	Aspartate ammonia-lyase
RU84_08675	COG0477	Major facilitator Superfamily
RU84_08695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RU84_08700	COG4521	taurine ABC transporter
RU84_08725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RU84_08730	COG1733	regulation of RNA biosynthetic process
RU84_08735	COG2207	Transcriptional regulator
RU84_08735	COG3708	Transcriptional regulator
RU84_08750	COG0730	response to heat
RU84_08770	COG3781	membrane
RU84_08775	COG1063	alcohol dehydrogenase
RU84_08785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RU84_08790	COG0508	dehydrogenase complex catalyzes the overall conversion of
RU84_08795	COG0022	dehydrogenase e1 component
RU84_08800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RU84_08805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RU84_08820	COG3706	GGDEF domain
RU84_08835	COG0133	tryptophan synthase activity
RU84_08850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RU84_08875	COG2226	methyltransferase
RU84_08930	COG0842	Transport permease protein
RU84_08935	COG0842	Transport permease protein
RU84_08940	COG1131	(ABC) transporter
RU84_08955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RU84_08960	COG4773	Receptor
RU84_08980	COG0730	response to heat
RU84_08985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RU84_09000	COG0406	alpha-ribazole phosphatase activity
RU84_09020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RU84_09050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RU84_09060	COG4264	IucA IucC family
RU84_09065	COG4264	IucA IucC family
RU84_09070	COG2814	Major facilitator Superfamily
RU84_09085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RU84_09100	COG1960	acyl-CoA dehydrogenase activity
RU84_09105	COG1960	acyl-CoA dehydrogenase activity
RU84_09110	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RU84_09115	COG2207	Transcriptional regulator
RU84_09120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RU84_09125	COG0776	regulation of translation
RU84_09150	COG0822	iron-sulfur transferase activity
RU84_09155	COG0316	Belongs to the HesB IscA family
RU84_09185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RU84_09205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RU84_09210	COG0702	epimerase
RU84_09245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RU84_09255	COG0339	signal peptide processing
RU84_09295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RU84_09300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RU84_09330	COG0776	regulation of translation
RU84_09350	COG0590	tRNA wobble adenosine to inosine editing
RU84_09380	COG2165	general secretion pathway protein
RU84_09395	COG0084	hydrolase, TatD family'
RU84_09415	COG1663	tetraacyldisaccharide 4'-kinase activity
RU84_09420	COG1132	(ABC) transporter
RU84_09430	COG0811	peptide transport
RU84_09435	COG1475	DNA binding
RU84_09440	COG1192	Involved in chromosome partitioning
RU84_09450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RU84_09465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RU84_09470	COG0191	fructose-bisphosphate aldolase activity
RU84_09490	COG0424	maF-like protein
RU84_09495	COG2850	peptidyl-arginine hydroxylation
RU84_09505	COG0640	Transcriptional regulator
RU84_09515	COG3619	membrane
RU84_09520	COG3122	Protein conserved in bacteria
RU84_09525	COG1132	(ABC) transporter
RU84_09545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RU84_09550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RU84_09560	COG0506	proline dehydrogenase activity
RU84_09560	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RU84_09560	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RU84_09565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RU84_09580	COG3698	Phosphodiester glycosidase
RU84_09590	COG2353	YceI-like domain
RU84_09600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RU84_09645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RU84_09645	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RU84_09670	COG3539	Fimbrial protein
RU84_09675	COG3121	Chaperone
RU84_09700	COG0697	spore germination
RU84_09710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RU84_09720	COG0583	DNA-binding transcription factor activity
RU84_09760	COG1522	sequence-specific DNA binding
RU84_09770	COG1126	abc transporter atp-binding protein
RU84_09775	COG0765	amino acid transport
RU84_09780	COG0765	amino acid transport
RU84_09810	COG1464	Belongs to the NlpA lipoprotein family
RU84_09820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RU84_09825	COG2011	ABC-type metal ion transport system permease component
RU84_09830	COG0012	GTP binding
RU84_09855	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RU84_09900	COG0386	Belongs to the glutathione peroxidase family
RU84_09910	COG0436	Aminotransferase
RU84_09950	COG3634	alkyl hydroperoxide reductase activity
RU84_09965	COG0583	DNA-binding transcription factor activity
RU84_09970	COG0798	PFAM Bile acid sodium symporter
RU84_09975	COG0640	Transcriptional regulator
RU84_09990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RU84_10000	COG0583	DNA-binding transcription factor activity
RU84_10010	COG1953	Uracil, thiamine, allantoin
RU84_10020	COG2175	clavaminate synthase activity
RU84_10025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RU84_10030	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RU84_10035	COG4521	taurine ABC transporter
RU84_10045	COG0477	Major facilitator Superfamily
RU84_10065	COG1271	oxidase subunit
RU84_10070	COG1294	oxidase, subunit
RU84_10080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RU84_10100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RU84_10120	COG3052	prosthetic group binding
RU84_10125	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
RU84_10135	COG0583	DNA-binding transcription factor activity
RU84_10145	COG2814	Major facilitator Superfamily
RU84_10165	COG1346	cytolysis
RU84_10175	COG0583	DNA-binding transcription factor activity
RU84_10180	COG0625	glutathione transferase activity
RU84_10185	COG0625	glutathione transferase activity
RU84_10190	COG0583	DNA-binding transcription factor activity
RU84_10200	COG2826	transposase and inactivated derivatives, IS30 family
RU84_10210	COG1045	serine acetyltransferase
RU84_10215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RU84_10220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RU84_10225	COG1280	lysine exporter protein (LysE YggA)
RU84_10235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RU84_10240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RU84_10250	COG0765	amino acid transport
RU84_10255	COG0765	amino acid transport
RU84_10270	COG2205	protein histidine kinase activity
RU84_10270	COG0784	Response regulator, receiver
RU84_10290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RU84_10305	COG2826	transposase and inactivated derivatives, IS30 family
RU84_10315	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_10365	COG0583	DNA-binding transcription factor activity
RU84_10385	COG0318	PFAM AMP-dependent synthetase and ligase
RU84_10390	COG1309	transcriptional regulator
RU84_10395	COG1960	acyl-CoA dehydrogenase activity
RU84_10400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RU84_10405	COG1024	Enoyl-CoA hydratase
RU84_10420	COG0583	DNA-binding transcription factor activity
RU84_10435	COG1960	acyl-CoA dehydrogenase activity
RU84_10445	COG2814	Major facilitator Superfamily
RU84_10455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RU84_10460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RU84_10465	COG2814	Major facilitator Superfamily
RU84_10470	COG1960	acyl-CoA dehydrogenase activity
RU84_10475	COG1024	Enoyl-CoA hydratase
RU84_10480	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_10485	COG1250	3-hydroxyacyl-CoA dehydrogenase
RU84_10490	COG0183	Belongs to the thiolase family
RU84_10500	COG2814	Major facilitator Superfamily
RU84_10510	COG1024	Enoyl-CoA hydratase
RU84_10525	COG1960	acyl-CoA dehydrogenase activity
RU84_10530	COG2814	Major facilitator Superfamily
RU84_10535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RU84_10555	COG3842	ATPase activity
RU84_10560	COG1840	ABC-type Fe3 transport system, periplasmic component
RU84_10580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RU84_10585	COG1414	Transcriptional regulator
RU84_10595	COG0583	DNA-binding transcription factor activity
RU84_10600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RU84_10605	COG1012	belongs to the aldehyde dehydrogenase family
RU84_10615	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RU84_10620	COG1012	belongs to the aldehyde dehydrogenase family
RU84_10625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RU84_10630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RU84_10635	COG2267	carboxylic ester hydrolase activity
RU84_10655	COG3038	cytochrome b561
RU84_10660	COG0753	catalase activity
RU84_10665	COG2271	Major facilitator Superfamily
RU84_10670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RU84_10675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RU84_10705	COG2050	protein possibly involved in aromatic compounds catabolism
RU84_10715	COG3327	negative regulation of DNA-templated transcription, initiation
RU84_10720	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
RU84_10725	COG0183	Belongs to the thiolase family
RU84_10730	COG1250	3-hydroxyacyl-CoA dehydrogenase
RU84_10735	COG1024	Enoyl-CoA hydratase
RU84_10740	COG1024	Enoyl-CoA hydratase
RU84_10745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RU84_10750	COG2151	metal-sulfur cluster biosynthetic enzyme
RU84_10755	COG3396	Phenylacetate-CoA oxygenase
RU84_10760	COG3460	Phenylacetate-CoA oxygenase
RU84_10765	COG3396	Phenylacetate-CoA oxygenase
RU84_10770	COG1012	belongs to the aldehyde dehydrogenase family
RU84_10770	COG2030	dehydratase
RU84_10775	COG1760	l-serine dehydratase
RU84_10780	COG0531	amino acid
RU84_10785	COG1012	belongs to the aldehyde dehydrogenase family
RU84_10810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RU84_10830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RU84_10840	COG0789	Transcriptional regulator
RU84_10855	COG2826	transposase and inactivated derivatives, IS30 family
RU84_10870	COG0038	chloride channel
RU84_10875	COG4770	biotin carboxylase activity
RU84_10895	COG1914	H( )-stimulated, divalent metal cation uptake system
RU84_10900	COG0583	DNA-binding transcription factor activity
RU84_10940	COG3209	COG3209 Rhs family protein
RU84_10945	COG3501	Rhs element vgr protein
RU84_10970	COG1250	3-hydroxyacyl-CoA dehydrogenase
RU84_10990	COG2814	Major facilitator Superfamily
RU84_11005	COG0598	Magnesium transport protein CorA
RU84_11010	COG1560	Kdo2-lipid A biosynthetic process
RU84_11015	COG5001	Diguanylate cyclase
RU84_11015	COG2203	Gaf domain
RU84_11015	COG3706	GGDEF domain
RU84_11015	COG4251	negative regulation of phosphorylation
RU84_11020	COG5006	permease, DMT superfamily
RU84_11025	COG1522	sequence-specific DNA binding
RU84_11040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RU84_11080	COG1538	Outer membrane efflux protein
RU84_11085	COG1137	ATPase activity
RU84_11090	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RU84_11100	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RU84_11105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RU84_11105	COG0517	IMP dehydrogenase activity
RU84_11145	COG1733	regulation of RNA biosynthetic process
RU84_11150	COG2814	Major facilitator Superfamily
RU84_11180	COG1278	Cold shock
RU84_11185	COG1280	lysine exporter protein (LysE YggA)
RU84_11215	COG1570	exodeoxyribonuclease VII activity
RU84_11295	COG2871	sodium ion transport
RU84_11305	COG0583	DNA-binding transcription factor activity
RU84_11310	COG4638	Rieske (2fe-2S)
RU84_11315	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
RU84_11320	COG0543	2 iron, 2 sulfur cluster binding
RU84_11320	COG0633	Ferredoxin
RU84_11325	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_11330	COG3135	benzoate transporter
RU84_11335	COG2814	Major facilitator Superfamily
RU84_11350	COG1643	Atp-dependent helicase
RU84_11355	COG0450	alkyl hydroperoxide reductase
RU84_11365	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RU84_11375	COG3634	alkyl hydroperoxide reductase activity
RU84_11395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RU84_11400	COG0625	glutathione transferase activity
RU84_11410	COG2885	chlorophyll binding
RU84_11465	COG1765	OsmC-like protein
RU84_11475	COG0667	Aldo Keto reductase
RU84_11490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RU84_11505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RU84_11525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RU84_11535	COG3038	cytochrome b561
RU84_11540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RU84_11545	COG2252	PERMEase
RU84_11555	COG2072	flavoprotein involved in K transport
RU84_11570	COG1741	Belongs to the pirin family
RU84_11575	COG1309	transcriptional regulator
RU84_11585	COG0300	oxidoreductase activity
RU84_11595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RU84_11640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RU84_11655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RU84_11670	COG2814	Major facilitator Superfamily
RU84_11675	COG1024	Enoyl-CoA hydratase
RU84_11680	COG1012	belongs to the aldehyde dehydrogenase family
RU84_11690	COG1960	acyl-CoA dehydrogenase activity
RU84_11715	COG2186	Transcriptional regulator
RU84_11720	COG1012	belongs to the aldehyde dehydrogenase family
RU84_11730	COG4948	Mandelate Racemase Muconate Lactonizing
RU84_11735	COG2271	Major facilitator Superfamily
RU84_11745	COG0697	spore germination
RU84_11785	COG1113	amino acid transport
RU84_11805	COG1012	belongs to the aldehyde dehydrogenase family
RU84_11825	COG0531	amino acid
RU84_11835	COG1113	amino acid transport
RU84_11870	COG3209	COG3209 Rhs family protein
RU84_11875	COG3501	Rhs element vgr protein
RU84_11890	COG4269	membrane
RU84_11935	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
RU84_11940	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
RU84_11970	COG2826	transposase and inactivated derivatives, IS30 family
RU84_11985	COG1401	restriction endodeoxyribonuclease activity
RU84_12060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RU84_12065	COG0582	viral genome integration into host DNA
RU84_12075	COG1902	pentaerythritol trinitrate reductase activity
RU84_12075	COG0446	pyridine nucleotide-disulphide oxidoreductase
RU84_12085	COG2203	Gaf domain
RU84_12085	COG3706	GGDEF domain
RU84_12085	COG4251	negative regulation of phosphorylation
RU84_12085	COG5001	Diguanylate cyclase
RU84_12095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RU84_12115	COG4172	Belongs to the ABC transporter superfamily
RU84_12120	COG4239	(ABC) transporter, permease
RU84_12125	COG4174	ABC transporter (Permease)
RU84_12135	COG0741	lytic transglycosylase activity
RU84_12135	COG1388	LysM domain
RU84_12135	COG0741	lytic transglycosylase activity
RU84_12135	COG1388	LysM domain
RU84_12140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RU84_12180	COG0583	DNA-binding transcription factor activity
RU84_12185	COG1279	arginine transmembrane transporter activity
RU84_12205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RU84_12210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RU84_12215	COG0006	proline dipeptidase activity
RU84_12305	COG0739	heme binding
RU84_12320	COG1598	PFAM Uncharacterised protein family UPF0150
RU84_12420	COG5410	chromosome segregation
RU84_12445	COG2826	transposase and inactivated derivatives, IS30 family
RU84_12530	COG3620	sequence-specific DNA binding
RU84_12600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RU84_12615	COG3384	dioxygenase
RU84_12625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RU84_12630	COG2878	Part of a membrane complex involved in electron transport
RU84_12635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RU84_12655	COG0768	penicillin binding
RU84_12660	COG0742	ribosomal rna small subunit methyltransferase
RU84_12675	COG0830	nickel cation binding
RU84_12685	COG0804	urea catabolic process
RU84_12725	COG1253	flavin adenine dinucleotide binding
RU84_12730	COG2851	Citrate transporter
RU84_12775	COG1773	rubredoxin
RU84_12780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RU84_12790	COG0583	DNA-binding transcription factor activity
RU84_12815	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RU84_12820	COG4181	ATPase activity
RU84_12865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RU84_12885	COG0306	phosphate transporter
RU84_12895	COG3958	Transketolase
RU84_12900	COG3959	Transketolase, thiamine diphosphate binding domain
RU84_12905	COG2271	Major facilitator Superfamily
RU84_12910	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_12915	COG0583	DNA-binding transcription factor activity
RU84_12930	COG2223	nitrite transmembrane transporter activity
RU84_12940	COG2066	Belongs to the glutaminase family
RU84_12945	COG0242	peptide deformylase activity
RU84_12950	COG0477	Major facilitator Superfamily
RU84_12960	COG0028	Belongs to the TPP enzyme family
RU84_12965	COG1012	belongs to the aldehyde dehydrogenase family
RU84_12975	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_12980	COG2267	carboxylic ester hydrolase activity
RU84_12990	COG2271	Major facilitator Superfamily
RU84_13005	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_13025	COG1414	Transcriptional regulator
RU84_13040	COG1024	Enoyl-CoA hydratase
RU84_13050	COG1215	transferase activity, transferring glycosyl groups
RU84_13055	COG1649	PFAM Uncharacterised BCR, COG1649
RU84_13055	COG0726	polysaccharide deacetylase
RU84_13065	COG4681	YaeQ
RU84_13075	COG0523	cobalamin synthesis protein
RU84_13085	COG1607	acyl-coa hydrolase
RU84_13095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RU84_13100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RU84_13105	COG1309	transcriptional regulator
RU84_13130	COG2040	homocysteine
RU84_13135	COG0531	amino acid
RU84_13160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RU84_13165	COG0477	Major facilitator Superfamily
RU84_13300	COG0592	DNA-directed DNA polymerase activity
RU84_13465	COG3755	Protein conserved in bacteria
RU84_13510	COG1484	DNA-dependent DNA replication
RU84_13600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RU84_13660	COG0405	Gamma-glutamyltransferase
RU84_13665	COG2814	Major facilitator Superfamily
RU84_13675	COG2050	protein possibly involved in aromatic compounds catabolism
RU84_13690	COG1090	epimerase
RU84_13710	COG0420	3'-5' exonuclease activity
RU84_13735	COG0735	belongs to the Fur family
RU84_13740	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RU84_13760	COG0121	glutamine amidotransferase
RU84_13775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RU84_13785	COG0210	DNA helicase
RU84_13790	COG2885	chlorophyll binding
RU84_13795	COG0204	Acyl-transferase
RU84_13810	COG2894	cell division
RU84_13830	COG1280	lysine exporter protein (LysE YggA)
RU84_13835	COG1674	ftsk spoiiie
RU84_13840	COG0492	ferredoxin-NADP+ reductase activity
RU84_13845	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
RU84_13855	COG0456	acetyltransferase
RU84_13915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RU84_13915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RU84_13935	COG1012	belongs to the aldehyde dehydrogenase family
RU84_13955	COG0473	3-isopropylmalate dehydrogenase activity
RU84_13960	COG0583	DNA-binding transcription factor activity
RU84_13975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RU84_13985	COG0582	viral genome integration into host DNA
RU84_14220	COG0305	Participates in initiation and elongation during chromosome replication
RU84_14240	COG3620	sequence-specific DNA binding
RU84_14255	COG2826	transposase and inactivated derivatives, IS30 family
RU84_14335	COG0564	pseudouridine synthase activity
RU84_14345	COG0358	DNA primase activity
RU84_14360	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
RU84_14390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RU84_14420	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RU84_14430	COG0352	thiamine-phosphate diphosphorylase activity
RU84_14430	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RU84_14430	COG0351	phosphomethylpyrimidine kinase
RU84_14435	COG1652	LysM domain
RU84_14460	COG1399	metal-binding, possibly nucleic acid-binding protein
RU84_14465	COG3101	peptidyl-lysine hydroxylation
RU84_14470	COG0009	L-threonylcarbamoyladenylate synthase
RU84_14475	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RU84_14480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RU84_14495	COG4106	trans-aconitate 2-methyltransferase activity
RU84_14510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RU84_14510	COG2226	methyltransferase
RU84_14510	COG0596	Alpha beta hydrolase
RU84_14515	COG1877	trehalose-phosphatase activity
RU84_14520	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RU84_14525	COG2223	nitrite transmembrane transporter activity
RU84_14545	COG1196	nuclear chromosome segregation
RU84_14555	COG0730	response to heat
RU84_14570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RU84_14580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RU84_14635	COG0489	protein tyrosine kinase activity
RU84_14645	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RU84_14645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RU84_14675	COG2515	1-aminocyclopropane-1-carboxylate deaminase
RU84_14680	COG2081	HI0933 family
RU84_14690	COG0668	transmembrane transport
RU84_14710	COG0583	DNA-binding transcription factor activity
RU84_14730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RU84_14735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RU84_14765	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RU84_14790	COG3706	GGDEF domain
RU84_14800	COG2205	protein histidine kinase activity
RU84_14805	COG0745	RESPONSE REGULATOR receiver
RU84_14825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RU84_14860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RU84_14865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RU84_14885	COG1473	amidohydrolase
RU84_14895	COG0583	DNA-binding transcription factor activity
RU84_14910	COG0583	DNA-binding transcription factor activity
RU84_14915	COG1053	succinate dehydrogenase
RU84_14930	COG1309	transcriptional regulator
RU84_14935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RU84_14940	COG2814	Major facilitator Superfamily
RU84_14945	COG1960	acyl-CoA dehydrogenase activity
RU84_14950	COG0583	DNA-binding transcription factor activity
RU84_14955	COG1063	alcohol dehydrogenase
RU84_14985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RU84_14990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RU84_14995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RU84_15015	COG2132	Multicopper oxidase
RU84_15025	COG0561	phosphatase activity
RU84_15030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RU84_15055	COG1214	PFAM Peptidase M22, glycoprotease
RU84_15110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RU84_15120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RU84_15125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RU84_15130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RU84_15190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RU84_15200	COG1846	Transcriptional regulator
RU84_15205	COG1764	response to oxidative stress
RU84_15230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RU84_15230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RU84_15245	COG0037	tRNA processing
RU84_15255	COG0248	Ppx GppA phosphatase
RU84_15280	COG0072	phenylalanine-tRNA ligase activity
RU84_15305	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RU84_15320	COG1238	metal cluster binding
RU84_15325	COG0625	glutathione transferase activity
RU84_15340	COG0318	PFAM AMP-dependent synthetase and ligase
RU84_15345	COG3028	Belongs to the UPF0307 family
RU84_15350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RU84_15370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RU84_15375	COG0617	tRNA 3'-terminal CCA addition
RU84_15380	COG1555	photosystem II stabilization
RU84_15385	COG3956	TIGRFAM MazG family protein
RU84_15395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RU84_15415	COG2205	protein histidine kinase activity
RU84_15415	COG0784	Response regulator, receiver
RU84_15415	COG5002	protein histidine kinase activity
RU84_15420	COG1024	Enoyl-CoA hydratase
RU84_15425	COG2084	Dehydrogenase
RU84_15430	COG3622	Belongs to the hyi family
RU84_15445	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RU84_15450	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RU84_15455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RU84_15460	COG0697	spore germination
RU84_15470	COG2814	Major facilitator Superfamily
RU84_15495	COG2072	flavoprotein involved in K transport
RU84_15500	COG0492	ferredoxin-NADP+ reductase activity
RU84_15505	COG0431	NADPH-dependent FMN reductase
RU84_15510	COG0798	PFAM Bile acid sodium symporter
RU84_15520	COG0640	Transcriptional regulator
RU84_15555	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RU84_15580	COG2132	Multicopper oxidase
RU84_15595	COG2205	protein histidine kinase activity
RU84_15670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RU84_15685	COG2826	transposase and inactivated derivatives, IS30 family
RU84_15690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RU84_15700	COG0084	hydrolase, TatD family'
RU84_15715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RU84_15745	COG0440	acetolactate synthase activity
RU84_15750	COG0028	Belongs to the TPP enzyme family
RU84_15775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RU84_15780	COG0577	efflux transmembrane transporter activity
RU84_15780	COG1136	(ABC) transporter
RU84_15785	COG1538	Outer membrane efflux protein
RU84_15800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RU84_15805	COG1162	GTPase activity
RU84_15815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RU84_15855	COG1426	Protein conserved in bacteria
RU84_15890	COG0793	Belongs to the peptidase S41A family
RU84_15915	COG1012	belongs to the aldehyde dehydrogenase family
RU84_15920	COG3265	gluconokinase activity
RU84_15930	COG0800	Aldolase
RU84_15940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RU84_15945	COG0857	belongs to the CobB CobQ family
RU84_15945	COG0280	phosphate acetyltransferase
RU84_15950	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RU84_15950	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RU84_15970	COG0740	serine-type endopeptidase activity
RU84_15980	COG4774	siderophore transport
RU84_15990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RU84_16000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RU84_16000	COG2813	Specifically methylates the guanine in position
RU84_16100	COG0788	formyltetrahydrofolate deformylase activity
RU84_16115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RU84_16120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RU84_16125	COG4651	solute:proton antiporter activity
RU84_16125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RU84_16145	COG0724	RNA recognition motif
RU84_16150	COG0210	DNA helicase
RU84_16175	COG1733	regulation of RNA biosynthetic process
RU84_16195	COG1280	lysine exporter protein (LysE YggA)
RU84_16200	COG1560	Kdo2-lipid A biosynthetic process
RU84_16210	COG1301	dicarboxylic acid transport
RU84_16235	COG0252	asparaginase activity
RU84_16265	COG0473	3-isopropylmalate dehydrogenase activity
RU84_16320	COG0583	DNA-binding transcription factor activity
RU84_16330	COG0625	glutathione transferase activity
RU84_16335	COG2378	regulation of single-species biofilm formation
RU84_16340	COG0546	phosphoglycolate phosphatase activity
RU84_16350	COG1530	ribonuclease E activity
RU84_16370	COG0583	DNA-binding transcription factor activity
RU84_16375	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_16380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RU84_16390	COG0534	Mate efflux family protein
RU84_16405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RU84_16490	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
RU84_16495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RU84_16510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RU84_16520	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RU84_16520	COG0644	oxidoreductase
RU84_16530	COG0425	Belongs to the sulfur carrier protein TusA family
RU84_16535	COG4535	Mg2 and Co2 transporter CorC
RU84_16545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RU84_16565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RU84_16570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RU84_16570	COG0475	glutathione-regulated potassium exporter activity
RU84_16585	COG0484	heat shock protein binding
RU84_16590	COG0789	Transcriptional regulator
RU84_16595	COG0598	Magnesium transport protein CorA
RU84_16615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RU84_16620	COG1074	ATP-dependent DNA helicase activity
RU84_16625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
RU84_16645	COG2226	methyltransferase
RU84_16655	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RU84_16670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RU84_16685	COG2111	Na H antiporter
RU84_16685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RU84_16690	COG1006	Multisubunit Na H antiporter MnhC subunit
RU84_16695	COG0651	ATP synthesis coupled electron transport
RU84_16705	COG2212	antiporter activity
RU84_16725	COG0195	Participates in both transcription termination and antitermination
RU84_16775	COG0237	dephospho-CoA kinase activity
RU84_16785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RU84_16800	COG0497	DNA recombination
RU84_16810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RU84_16840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RU84_16840	COG2169	Transcriptional regulator
RU84_16845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RU84_16900	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RU84_16915	COG0326	Molecular chaperone. Has ATPase activity
RU84_16930	COG2056	Na+-H+ antiporter family
RU84_17030	COG0546	phosphoglycolate phosphatase activity
RU84_17035	COG1716	ATPase activity
RU84_17080	COG0181	hydroxymethylbilane synthase activity
RU84_17090	COG3275	phosphorelay sensor kinase activity
RU84_17115	COG0697	spore germination
RU84_17140	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RU84_17145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RU84_17150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RU84_17155	COG0772	Belongs to the SEDS family
RU84_17180	COG4974	Belongs to the 'phage' integrase family
RU84_17185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RU84_17195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RU84_17205	COG2197	response regulator
RU84_17220	COG0793	Belongs to the peptidase S41A family
RU84_17225	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RU84_17230	COG0795	lipopolysaccharide-transporting ATPase activity
RU84_17270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RU84_17270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RU84_17280	COG0004	ammonium transporteR
RU84_17285	COG0347	Belongs to the P(II) protein family
RU84_17295	COG0606	chelatase, subunit chli
RU84_17300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RU84_17310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RU84_17325	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RU84_17340	COG0318	PFAM AMP-dependent synthetase and ligase
RU84_17350	COG0477	Major facilitator Superfamily
RU84_17355	COG2860	membrane
RU84_17365	COG1253	flavin adenine dinucleotide binding
RU84_17375	COG2814	Major facilitator Superfamily
RU84_17385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RU84_17420	COG0655	NAD(P)H dehydrogenase (quinone) activity
RU84_17430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RU84_17465	COG1309	transcriptional regulator
RU84_17500	COG0758	DNA mediated transformation
RU84_17510	COG0697	spore germination
RU84_17515	COG1309	transcriptional regulator
RU84_17530	COG0386	Belongs to the glutathione peroxidase family
RU84_17595	COG1121	(ABC) transporter
RU84_17600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RU84_17605	COG1280	lysine exporter protein (LysE YggA)
RU84_17610	COG2837	iron assimilation
RU84_17615	COG0281	malic enzyme
RU84_17660	COG0519	Catalyzes the synthesis of GMP from XMP
RU84_17660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RU84_17665	COG4399	Belongs to the UPF0754 family
RU84_17670	COG2259	Doxx family
RU84_17675	COG0586	Pfam SNARE associated Golgi protein
RU84_17690	COG1192	Involved in chromosome partitioning
RU84_17700	COG0271	Belongs to the BolA IbaG family
RU84_17740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RU84_17740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RU84_17740	COG3321	synthase
RU84_17740	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RU84_17745	COG1960	acyl-CoA dehydrogenase activity
RU84_17755	COG2197	response regulator
RU84_17765	COG3916	Acyl-homoserine-lactone synthase
RU84_17770	COG0477	Major facilitator Superfamily
RU84_17775	COG1024	Enoyl-CoA hydratase
RU84_17780	COG1024	Enoyl-CoA hydratase
RU84_17785	COG1960	acyl-CoA dehydrogenase activity
RU84_17790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RU84_17810	COG1113	amino acid transport
RU84_17815	COG1113	amino acid transport
RU84_17820	COG0251	oxidation-reduction process
RU84_17835	COG1522	sequence-specific DNA binding
RU84_17860	COG0564	pseudouridine synthase activity
RU84_17890	COG1051	belongs to the nudix hydrolase family
RU84_17905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RU84_17920	COG1802	Transcriptional regulator
RU84_17925	COG1448	Aminotransferase
RU84_17930	COG0277	FAD linked oxidase domain protein
RU84_17940	COG2186	Transcriptional regulator
RU84_17950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RU84_17955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RU84_17970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RU84_17975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RU84_17980	COG1216	Glycosyl transferase, family 2
RU84_18000	COG2244	polysaccharide biosynthetic process
RU84_18005	COG2089	acid synthase
RU84_18020	COG1083	cytidylyl-transferase
RU84_18025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RU84_18030	COG1086	Polysaccharide biosynthesis protein
RU84_18035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RU84_18065	COG0728	peptidoglycan biosynthetic process
RU84_18070	COG3023	N-Acetylmuramoyl-L-alanine amidase
RU84_18125	COG0546	phosphoglycolate phosphatase activity
RU84_18130	COG1028	Short-chain dehydrogenase reductase Sdr
RU84_18150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RU84_18155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RU84_18160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RU84_18165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RU84_18170	COG1116	anion transmembrane transporter activity
RU84_18175	COG1309	transcriptional regulator
RU84_18180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RU84_18190	COG0196	riboflavin kinase activity
RU84_18195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RU84_18205	COG1047	Peptidyl-prolyl cis-trans
RU84_18245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RU84_18270	COG0583	DNA-binding transcription factor activity
RU84_18300	COG2951	lytic endotransglycosylase activity
RU84_18305	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RU84_18325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RU84_18335	COG0671	phosphoesterase, PA-phosphatase related
RU84_18340	COG0861	Integral membrane protein TerC family
RU84_18350	COG0754	glutathionylspermidine amidase activity
RU84_18360	COG0402	S-adenosylhomocysteine deaminase activity
RU84_18380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RU84_18385	COG1230	cation diffusion facilitator family transporter
RU84_18400	COG0706	membrane insertase activity
RU84_18415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RU84_18450	COG0194	GDP metabolic process
RU84_18475	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RU84_18520	COG0587	DNA-directed DNA polymerase activity
RU84_18535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RU84_18535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RU84_18585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RU84_18585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RU84_18590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RU84_18620	COG3316	Transposase and inactivated derivatives
RU84_18630	COG2194	sulfuric ester hydrolase activity
RU84_18645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RU84_18690	COG2130	NADP-dependent
RU84_18700	COG1309	transcriptional regulator
RU84_18710	COG1902	pentaerythritol trinitrate reductase activity
RU84_18720	COG1979	alcohol dehydrogenase
RU84_18730	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RU84_18760	COG1063	alcohol dehydrogenase
RU84_18825	COG1388	LysM domain
RU84_18840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RU84_18860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RU84_19040	COG0358	DNA primase activity
RU84_19060	COG0673	inositol 2-dehydrogenase activity
RU84_19120	COG1525	nuclease
RU84_19145	COG1196	nuclear chromosome segregation
RU84_19145	COG0739	heme binding
RU84_19145	COG0741	lytic transglycosylase activity
RU84_19160	COG0739	heme binding
RU84_19160	COG0741	lytic transglycosylase activity
RU84_19160	COG1196	nuclear chromosome segregation
RU84_19220	COG1192	Involved in chromosome partitioning
RU84_19285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RU84_19335	COG0589	response to stress
RU84_19340	COG0659	secondary active sulfate transmembrane transporter activity
RU84_19345	COG4683	PFAM Phage derived protein Gp49-like (DUF891)