locus-tag class description A320_00001 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) A320_00002 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) A320_00003 ENOG4105D74 hydrolase A320_00005 ENOG4108821 RND type efflux pump A320_00006 ENOG4108821 RND type efflux pump A320_00007 ENOG4108821 RND type efflux pump A320_00008 ENOG4105C5H ABC transporter A320_00009 ENOG4105DQR SNARE associated Golgi A320_00011 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) A320_00013 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) A320_00015 ENOG4105VG0 50S ribosomal protein l34 A320_00018 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins A320_00021 ENOG4105PGM cation diffusion facilitator family transporter A320_00022 ENOG4105T95 Thiol disulfide interChange protein A320_00024 ENOG4108UGV hypoxanthine phosphoribosyltransferase A320_00026 ENOG4107QUY Guanine deaminase A320_00028 ENOG4106032 Glutathionylspermidine synthase A320_00031 ENOG4105DU1 integral membrane protein, terc A320_00032 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase A320_00034 ENOG4105DFU Cell wall formation (By similarity) A320_00036 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) A320_00037 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit A320_00038 ENOG4105CVE Lytic murein transglycosylase A320_00049 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) A320_00057 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase A320_00059 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) A320_00060 ENOG4105DTN riboflavin biosynthesis protein ribF A320_00062 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) A320_00063 ENOG4108R86 Transcriptional regulator A320_00064 ENOG4108VM9 ABC, transporter A320_00065 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component A320_00066 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) A320_00067 ENOG4105GVF (ABC) transporter A320_00068 ENOG4105GVF (ABC) transporter A320_00069 ENOG4107QZM n-acetylglutamate synthase A320_00072 ENOG4105UBK short-chain dehydrogenase reductase A320_00073 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) A320_00076 ENOG41062JF Transcriptional regulator A320_00081 ENOG4105HSS phospholipase C A320_00083 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase A320_00084 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase A320_00085 ENOG4105CJR Integral membrane protein (MviN A320_00086 ENOG4108V1T peptidylprolyl cis-trans isomerase A320_00087 ENOG4108V1T peptidylprolyl cis-trans isomerase A320_00088 ENOG4105D75 Capsular exopolysaccharide family A320_00090 ENOG4105DAY polysaccharide export protein A320_00091 ENOG4107QQG Dehydrogenase A320_00102 ENOG4107UKG Glycosyl transferase, family 4 A320_00103 ENOG4105D3Q Sugar transferase A320_00104 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase A320_00105 ENOG4105C6Y Udp-glucose 6-dehydrogenase A320_00107 ENOG4105CMR udp-glucose 4-epimerase A320_00108 ENOG4107QKV phosphomannomutase A320_00109 ENOG4105DAA L-lactate A320_00110 ENOG41073TP transcriptional regulator A320_00112 ENOG4105CXG d-lactate dehydrogenase A320_00113 ENOG4105CGF Aromatic amino acid aminotransferase A320_00114 ENOG4105DRR Transcriptional regulator, GntR family A320_00115 ENOG4105CR4 methylisocitrate lyase A320_00116 ENOG4105BZN citrate synthase A320_00117 ENOG4108I0Z Aconitate hydratase A320_00120 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) A320_00125 ENOG4105D3G Pseudouridine synthase A320_00130 ENOG4105EW9 transcriptional regulator AsnC family A320_00133 ENOG4105M4H endoribonuclease L-psp A320_00134 ENOG4105C85 amino acid A320_00135 ENOG4105C85 amino acid A320_00137 ENOG4105C26 Dehydrogenase A320_00138 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase A320_00140 ENOG4105C1G acyl-Coa dehydrogenase A320_00141 ENOG4105E39 Enoyl-CoA hydratase A320_00142 ENOG4105E39 Enoyl-CoA hydratase A320_00143 ENOG4105CSH Transporter A320_00148 ENOG4105C1G acyl-Coa dehydrogenase A320_00153 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) A320_00157 ENOG4107PSF BolA-like protein A320_00159 ENOG4107QJE Chromosome Partitioning Protein A320_00162 ENOG4105DQR SNARE associated Golgi A320_00163 ENOG4108VBZ doxx family A320_00164 ENOG4106MP8 UPF0754 membrane protein A320_00165 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) A320_00169 ENOG4105EUB pirin domain protein A320_00174 ENOG4107R1I NAD-dependent malic enzyme A320_00176 ENOG4105EZR dyp-type peroxidase family protein A320_00178 ENOG4105FAV ABC, transporter A320_00179 ENOG4105FDK ABC transporter A320_00184 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) A320_00192 ENOG4108V06 Glutathione peroxidase A320_00194 ENOG4107RTG Major Facilitator superfamily A320_00195 ENOG4108IND Tetr family transcriptional regulator A320_00198 ENOG4105C79 DNA protecting protein DprA A320_00205 ENOG4105Y7M Transcriptional regulator, TetR family A320_00212 ENOG4105C6T cysteine synthase A320_00214 ENOG4105CS1 NAD(P)H quinone oxidoreductase A320_00221 ENOG4105CCT upf0313 protein A320_00224 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) A320_00226 ENOG4105C0R drug resistance transporter emrb qaca subfamily A320_00227 ENOG4108URH decarboxylase A320_00228 ENOG4105EE5 Membrane protein terC A320_00230 ENOG4105EN6 Membrane A320_00231 ENOG41079KZ Major Facilitator Superfamily A320_00232 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) A320_00233 ENOG4105CEY Amp-dependent synthetase and ligase A320_00236 ENOG4105F0N pyrophosphate phospho-hydrolase A320_00237 ENOG4105EPF Outer membrane porin A320_00240 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) A320_00242 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A320_00250 ENOG4105CHH sulfate transporter A320_00258 ENOG4108R0M Aminoglycoside A320_00263 ENOG4105BZU Histidine kinase A320_00265 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) A320_00273 ENOG4108K5H permease YjgP YjgQ family protein A320_00274 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) A320_00275 ENOG4105CN1 protease A320_00276 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family A320_00277 ENOG4107TUY Histidine kinase A320_00279 ENOG41061WM D-Alanyl-D-Alanine A320_00281 ENOG4105D6E homoserine dehydrogenase A320_00282 ENOG4105T95 Thiol disulfide interChange protein A320_00283 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) A320_00285 ENOG4105CE1 Ferrous iron transport protein b A320_00288 ENOG4105CNI cell division protein FtsW A320_00289 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) A320_00290 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters A320_00291 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) A320_00296 ENOG4108RNG Permease of the drug metabolite transporter A320_00297 ENOG4105DFG type I secretion outer membrane protein A320_00298 ENOG4108UTW Plays a role in the regulation of phosphate uptake A320_00301 ENOG4108HRK Histidine kinase A320_00302 ENOG4108NEV two component transcriptional regulator, LytTR family A320_00303 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) A320_00308 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS A320_00311 ENOG4105GVR general secretion pathway protein D A320_00312 ENOG4105TV9 FHA Domain-Containing protein A320_00313 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) A320_00321 ENOG4105PM1 preprotein translocase subunit SecE A320_00322 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) A320_00332 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) A320_00333 ENOG4105D3Y Na H antiporter A320_00336 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) A320_00339 ENOG4107ZXU DSBA oxidoreductase A320_00353 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase A320_00354 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) A320_00360 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) A320_00362 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) A320_00365 ENOG4105C2N RNA methyltransferase TrmH family group 3 A320_00367 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) A320_00370 ENOG4107QHF type ii secretion system protein e A320_00372 ENOG4107EJC Preprotein translocase subunit SecG A320_00377 ENOG4105CHV Transcription elongation factor NusA A320_00380 ENOG4105KJM monovalent cation h antiporter subunit g A320_00381 ENOG4105W4C monovalent cation H antiporter subunit F A320_00382 ENOG4105SC1 monovalent cation H antiporter subunit E A320_00383 ENOG4107R4Z monovalent cation h antiporter subunit d A320_00384 ENOG4108ZE9 Monovalent cation H antiporter subunit C A320_00385 ENOG4105D65 subunit l A320_00388 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase A320_00389 ENOG41061H0 Monooxygenase A320_00392 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) A320_00394 ENOG4105CSR polyphosphate kinase 2 A320_00396 ENOG4105DSY exodeoxyribonuclease V, gamma A320_00397 ENOG4107QKA exodeoxyribonuclease V beta A320_00398 ENOG4107QYX exodeoxyribonuclease v alpha A320_00402 ENOG4107QUT magnesium and cobalt transport protein CorA A320_00403 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) A320_00404 ENOG4105DVC DnaJ domain protein A320_00406 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) A320_00407 ENOG4105CKD glutathione-regulated potassium-efflux system protein A320_00408 ENOG4105C25 Primosomal protein n' A320_00409 ENOG4105D7Q type ii secretion system A320_00410 ENOG4108VAU general secretion pathway protein G A320_00412 ENOG4108Z7R Chaperone CsaA A320_00413 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) A320_00414 ENOG4108JU5 Magnesium and cobalt efflux protein A320_00415 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) A320_00416 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase A320_00418 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) A320_00421 ENOG4105C5X domain protein A320_00422 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) A320_00430 ENOG4107T8P acyl-Coa dehydrogenase A320_00432 ENOG4107QI1 Mate efflux family protein A320_00434 ENOG4105CSA Coproporphyrinogen iii oxidase A320_00435 ENOG4105EMU Dehydrogenase A320_00436 ENOG4105CBN LysR family transcriptional regulator A320_00440 ENOG4105C03 ribonuclease A320_00441 ENOG4105EI2 Pseudouridine synthase A320_00442 ENOG4107XGZ Hydrolase A320_00443 ENOG4105D29 Helix-turn-helix type 11 domain protein A320_00446 ENOG4108W5M transcriptional regulator A320_00449 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase A320_00454 ENOG4105DUM transcriptional regulator, lysR family A320_00459 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) A320_00470 ENOG4105CK2 sodium dicarboxylate symporter A320_00472 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase A320_00473 ENOG4105N14 lysine exporter protein LysE YggA A320_00474 ENOG4105C5H ABC transporter A320_00475 ENOG41069P5 Protein slyX homolog A320_00477 ENOG4105KVH Transcriptional regulator A320_00479 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) A320_00482 ENOG4105C4R Atp-dependent dna helicase A320_00483 ENOG4105VFU Rna-binding protein A320_00487 ENOG4105CKD glutathione-regulated potassium-efflux system protein A320_00488 ENOG4105W0E 50S ribosomal protein L33 A320_00489 ENOG4105KDC 50s ribosomal protein l28 A320_00490 ENOG4107RGH Aldehyde dehydrogenase A320_00492 ENOG4105CIY formyltetrahydrofolate deformylase A320_00512 ENOG4105DWV Homoserine O-trans-acetylase A320_00514 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) A320_00516 ENOG4108ESX Receptor A320_00518 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) A320_00522 ENOG4107GFK fumarate A320_00523 ENOG4108DNC Involved in acetate metabolism (By similarity) A320_00524 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) A320_00525 ENOG4105C01 Dihydroxy-acid dehydratase A320_00526 ENOG4108UHU Aldolase A320_00527 ENOG4105C6Z Gluconate A320_00528 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family A320_00529 ENOG4105C26 Dehydrogenase A320_00531 ENOG4106HB6 Alpha beta hydrolase A320_00534 ENOG4105CN1 protease A320_00537 ENOG4105WVQ Fe-S assembly protein IscX A320_00541 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) A320_00545 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) A320_00549 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) A320_00552 ENOG4105CEY Amp-dependent synthetase and ligase A320_00555 ENOG4105C84 Histidine ammonia-lyase A320_00561 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) A320_00563 ENOG4105C2D reductase A320_00564 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) A320_00568 ENOG4105VW4 glutaredoxin 3 A320_00570 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) A320_00571 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) A320_00573 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH A320_00574 ENOG4105ENJ RND efflux system, outer membrane lipoprotein A320_00575 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) A320_00576 ENOG4105DJY efflux transporter, rnd family, mfp subunit A320_00581 ENOG4105C7K acetolactate synthase A320_00582 ENOG4108ZP8 Acetolactate synthase small subunit A320_00584 ENOG4105BZU Histidine kinase A320_00588 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) A320_00591 ENOG4105F8V Hydrolase, tatD family A320_00592 ENOG4107QM5 aconitate hydratase A320_00594 ENOG4105CUZ uba thif-type nad fad binding protein A320_00595 ENOG4107RSM transcriptional regulator A320_00597 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) A320_00600 ENOG4106UX7 integral membrane protein A320_00601 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) A320_00602 ENOG4105W8H transhydrogenase (subunit alpha A320_00603 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) A320_00606 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) A320_00607 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase A320_00608 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase A320_00609 ENOG4105BZU Histidine kinase A320_00610 ENOG4105C6T cysteine synthase A320_00613 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) A320_00615 ENOG4105DXN mazG family A320_00616 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein A320_00617 ENOG4105DJ0 Poly(A) Polymerase A320_00618 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase A320_00622 ENOG41080Z8 PHOSPHOCARRIER protein A320_00623 ENOG4105N42 UPF0307 protein A320_00624 ENOG4105CEY Amp-dependent synthetase and ligase A320_00627 ENOG4105CYM Glutathione S-transferase A320_00628 ENOG4105W39 Membrane A320_00631 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) A320_00636 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) A320_00639 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) A320_00641 ENOG4105C9X ppx gppa phosphatase A320_00643 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) A320_00644 ENOG4105II7 pyrroline-5-carboxylate reductase A320_00645 ENOG4108VIA integral membrane protein A320_00646 ENOG4105C2M dna polymerase I A320_00650 ENOG4107QHF type ii secretion system protein e A320_00651 ENOG4108ZHJ Organic hydroperoxide resistance protein A320_00652 ENOG4105K56 Transcriptional regulator A320_00666 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) A320_00667 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) A320_00668 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) A320_00670 ENOG4105CRQ synthase (Component I) A320_00680 ENOG4108Z0R Transferase A320_00681 ENOG41072GX Peptidase M22 Glycoprotease A320_00686 ENOG4105DJV ribulose-phosphate 3-epimerase A320_00687 ENOG4108HCJ Hydrolase A320_00689 ENOG4105E3B Multicopper oxidase A320_00690 ENOG4105VR0 copper resistance A320_00693 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) A320_00694 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) A320_00695 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) A320_00702 ENOG4105ETT transcriptional Regulator, LysR family A320_00703 ENOG4105C1G acyl-Coa dehydrogenase A320_00704 ENOG4107RGD Major Facilitator superfamily A320_00705 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F A320_00707 ENOG4107EFR Flavocytochrome c A320_00708 ENOG4106P55 Transcriptional regulator A320_00711 ENOG4106P55 Transcriptional regulator A320_00713 ENOG4105CH2 amidohydrolase A320_00717 ENOG4105ETT transcriptional Regulator, LysR family A320_00719 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) A320_00720 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) A320_00725 ENOG4105JAB phenazine biosynthesis protein, phzf family A320_00729 ENOG4105DZG Dehydrogenase A320_00743 ENOG4105EB3 Histidine kinase A320_00744 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) A320_00746 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) A320_00747 ENOG4107EXC regulatoR A320_00748 ENOG4105E0F Histidine kinase A320_00750 ENOG4105BZU Histidine kinase A320_00754 ENOG4105GKE subunit e A320_00755 ENOG4107QIZ NADH dehydrogenase A320_00756 ENOG4108IEH NADH dehydrogenase subunit g A320_00759 ENOG4107UFS subunit j A320_00761 ENOG4105D65 subunit l A320_00762 ENOG4105C8S subunit m A320_00766 ENOG4105DUM transcriptional regulator, lysR family A320_00767 ENOG4105DP0 ferredoxin-NADP reductase A320_00772 ENOG4105CBX hi0933 family A320_00773 ENOG4105K6H D-cysteine desulfhydrase A320_00779 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) A320_00781 ENOG4105D1F ATP-binding protein A320_00791 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) A320_00793 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY A320_00796 ENOG4105HF0 Membrane A320_00798 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) A320_00802 ENOG4106UW1 Major Facilitator superfamily A320_00803 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase A320_00804 ENOG4108K4C ec 3.1.3.12 A320_00805 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) A320_00807 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) A320_00808 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) A320_00810 ENOG4105FE9 pseudouridine synthase A320_00811 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) A320_00812 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) A320_00813 ENOG4107RTD sua5 ycio yrdc ywlc family protein A320_00814 ENOG4108BPE -transporting atpase A320_00815 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein A320_00817 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase A320_00818 ENOG4105CHR reductase A320_00820 ENOG4109066 lysm domain bon superfamily protein A320_00821 ENOG4105DWF phosphomethylpyrimidine kinase A320_00823 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) A320_00829 ENOG4105C5T Phosphoribosyl pyrophosphate synthase A320_00834 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) A320_00837 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) A320_00838 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane A320_00839 ENOG4105C34 Pseudouridine synthase A320_00840 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase A320_00844 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding A320_00847 ENOG4105EJC lysr family transcriptional regulator A320_00848 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) A320_00849 ENOG4105C94 Transporter A320_00851 ENOG4105DVW rieske (2Fe-2S) A320_00852 ENOG4105C26 Dehydrogenase A320_00853 ENOG4105E3J oxidoreductase A320_00856 ENOG4105C4K Nad synthetase A320_00858 ENOG4105EUB pirin domain protein A320_00859 ENOG4108YXA Membrane A320_00868 ENOG4105KEG ribosomal-protein-alanine acetyltransferase A320_00870 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) A320_00871 ENOG4105C3M thioredoxin reductase A320_00872 ENOG4105CNU cell division protein FtsK A320_00878 ENOG4107QMS site-determining protein A320_00881 ENOG4106HNH Acyl-transferase A320_00882 ENOG4108ZG0 Ompa motb domain protein A320_00884 ENOG4105C4R Atp-dependent dna helicase A320_00886 ENOG4107QKV phosphomannomutase A320_00889 ENOG4105E7A Glutamine amidotransferase A320_00894 ENOG41090R7 Ferric uptake A320_00895 ENOG4105CZX twitching motility protein A320_00896 ENOG4105CZX twitching motility protein A320_00897 ENOG4105DFA alanine racemase domain protein A320_00898 ENOG4105EYH Exonuclease A320_00899 ENOG4107RH8 nuclease SbcCD subunit D A320_00903 ENOG4105ECP epimerase A320_00904 ENOG4105MWK D-amino acid dehydrogenase, small subunit A320_00905 ENOG4105D52 delta-aminolevulinic acid dehydratase A320_00906 ENOG4108VUY thioesterase Superfamily protein A320_00907 ENOG4105CW7 secretion protein, HlyD family A320_00908 ENOG4105C0R drug resistance transporter emrb qaca subfamily A320_00909 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) A320_00917 ENOG4105C54 Major Facilitator superfamily A320_00918 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) A320_00923 ENOG4105D5Q Arginine ornithine antiporter A320_00924 ENOG4107QK5 Homocysteine s-methyltransferase A320_00929 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) A320_00930 ENOG4105C94 Transporter A320_00931 ENOG4105C94 Transporter A320_00935 ENOG4105CKI cobalamin synthesis protein A320_00937 ENOG4108VWS Yaeq family A320_00939 ENOG4107BJW polysaccharide deacetylase A320_00940 ENOG4105CND Glycosyl transferase, family 2 A320_00942 ENOG4106YT9 Enoyl-CoA hydratase A320_00945 ENOG41069M3 Transcriptional regulator A320_00949 ENOG4105CHR reductase A320_00951 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase A320_00952 ENOG4105DJB Major Facilitator Superfamily A320_00954 ENOG4108MXF Alpha Beta Hydrolase A320_00955 ENOG4105CHR reductase A320_00958 ENOG4105C7K acetolactate synthase A320_00960 ENOG4105CSH Transporter A320_00962 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) A320_00963 ENOG4105CSV Glutaminase A320_00964 ENOG4108R6W Transcriptional regulator, ARAC family A320_00965 ENOG4105EU0 Major facilitator Superfamily A320_00966 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) A320_00968 ENOG4108PZW LysR family Transcriptional regulator A320_00970 ENOG4105CSP Major Facilitator Superfamily A320_00973 ENOG4105C3R Methionine synthase A320_00974 ENOG4105CJ3 phosphate transporter A320_00978 ENOG4105E6M Sulphatase-modifying factor protein A320_00979 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) A320_00982 ENOG4107RNH Outer membrane receptor FepA A320_00986 ENOG4108UJV acyl-CoA thioesterase i A320_00987 ENOG4108I0Y (ABC) transporter A320_00988 ENOG4105CV6 ABC transporter, permease A320_00989 ENOG4107U91 Rhomboid family A320_00993 ENOG4105C5Q Transcriptional regulator A320_00995 ENOG4107QZF nitrite reductase NADPH large subunit A320_00996 ENOG4105VCQ rubredoxin A320_01000 ENOG4108MRJ A320_01003 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) A320_01006 ENOG4105D4T Citrate transporter A320_01007 ENOG4105C37 (CBS) domain A320_01009 ENOG4107RET Isocitrate lyase A320_01015 ENOG4105CQM Urea amidohydrolase subunit alpha A320_01016 ENOG4105CQM Urea amidohydrolase subunit alpha A320_01018 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) A320_01021 ENOG4106H78 methyltransferase A320_01022 ENOG4105CJN penicillin-binding protein A320_01026 ENOG4105CSM endonuclease III A320_01027 ENOG4108R3D Electron transport complex A320_01028 ENOG4105D82 Glutamate dehydrogenase A320_01030 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b A320_01035 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase A320_01099 ENOG4105DR5 peptidase A320_01108 ENOG4105DIJ Phosphoethanolamine transferase A320_01115 ENOG4107RAQ aminopeptidase A320_01116 ENOG4105D0A hydroxylase A320_01117 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family A320_01121 ENOG4108ZUB Lysine exporter protein (Lyse ygga) A320_01122 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) A320_01124 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) A320_01126 ENOG4105W4M Transport-associated protein A320_01128 ENOG4105E09 nadh pyrophosphatase A320_01130 ENOG4107RZZ dna polymerase iii epsilon subunit A320_01131 ENOG4105E9H Lytic Murein transglycosylase A320_01131 ENOG4105E9H Lytic Murein transglycosylase A320_01133 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component A320_01134 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component A320_01135 ENOG4108JQ5 ABC transporter A320_01139 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) A320_01143 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A320_01146 ENOG4108M3P Membrane A320_01147 ENOG4105D01 (LipO)protein A320_01151 ENOG4105CNA YD repeat protein A320_01159 ENOG4105C85 amino acid A320_01161 ENOG4105CUB amino acid A320_01165 ENOG4105C26 Dehydrogenase A320_01169 ENOG4105C85 amino acid A320_01170 ENOG4107RGH Aldehyde dehydrogenase A320_01171 ENOG4108ZX5 transcriptional regulator A320_01172 ENOG4105DJP Membrane A320_01173 ENOG4105CTX dehydratase A320_01174 ENOG4105DJB Major Facilitator Superfamily A320_01175 ENOG4105EQX glucarate dehydratase A320_01177 ENOG4105CZJ Aldehyde dehydrogenase A320_01178 ENOG4105JXH GntR family transcriptional regulator A320_01181 ENOG4105NI3 Protein of unknown function (DUF3237) A320_01182 ENOG4105EPF Outer membrane porin A320_01183 ENOG4105C1G acyl-Coa dehydrogenase A320_01186 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase A320_01187 ENOG4108SC4 )-transporter A320_01190 ENOG4105E3J oxidoreductase A320_01193 ENOG4105E6M Sulphatase-modifying factor protein A320_01194 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) A320_01195 ENOG4105D2S major facilitator superfamily A320_01196 ENOG4105EPF Outer membrane porin A320_01200 ENOG4107RN6 Monooxygenase A320_01202 ENOG4107GFK fumarate A320_01203 ENOG4106DSS Tartrate dehydratase subunit alpha A320_01205 ENOG4105EJC lysr family transcriptional regulator A320_01206 ENOG4105JQZ Methyltransferase A320_01207 ENOG4107RN6 Monooxygenase A320_01211 ENOG4105D13 transposase A320_01212 ENOG4108C33 Resolvase A320_01216 ENOG4105EUJ GTP cyclohydrolase i A320_01218 ENOG4105C7W Xanthine dehydrogenase A320_01224 ENOG4105CD8 aminopeptidase N A320_01225 ENOG4105DDQ anthranilate synthase A320_01227 ENOG4105DUX Transporter A320_01228 ENOG4105C5F glutamine synthetase A320_01230 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) A320_01237 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) A320_01238 ENOG4107QNR UPF0135 protein A320_01239 ENOG4105C0H protease A320_01241 ENOG4105C6K Malic enzyme A320_01242 ENOG4105BZU Histidine kinase A320_01243 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) A320_01244 ENOG4105SYT Methylenetetrahydrofolate reductase A320_01245 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) A320_01248 ENOG4107QPN acyl-Coa dehydrogenase A320_01249 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) A320_01250 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) A320_01253 ENOG4107RNU major facilitator superfamily MFS_1 A320_01255 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) A320_01256 ENOG4105CE9 30S ribosomal protein S2 A320_01264 ENOG4105CVE Lytic murein transglycosylase A320_01265 ENOG4105CNI cell division protein FtsW A320_01268 ENOG4105E3A (ABC) transporter A320_01269 ENOG4105DA5 (ABC) transporter A320_01276 ENOG4105ENJ RND efflux system, outer membrane lipoprotein A320_01278 ENOG4105ENT Efflux transporter rnd family, mfp subunit A320_01281 ENOG4105E89 ABC transporter A320_01282 ENOG4105DSP amino acid AbC transporter A320_01283 ENOG4106YG3 ABC transporter A320_01284 ENOG4108JEH abc transporter atp-binding protein A320_01286 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding A320_01287 ENOG4105CFP Peptidase U32 A320_01288 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A320_01289 ENOG4105JAB phenazine biosynthesis protein, phzf family A320_01290 ENOG4105DP0 ferredoxin-NADP reductase A320_01291 ENOG4108R96 Methyltransferase, YaeB family A320_01293 ENOG4107QHF type ii secretion system protein e A320_01295 ENOG4105XJC Two component transcriptional regulator (Winged helix family A320_01296 ENOG4105DHQ Histidine kinase A320_01298 ENOG4105M6F mutator MutT protein A320_01300 ENOG4105BZ4 penicillin-binding protein A320_01301 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) A320_01302 ENOG4105VUT cytoplasmic protein A320_01303 ENOG4107QYG anthranilate phosphoribosyltransferase A320_01304 ENOG4105CK2 sodium dicarboxylate symporter A320_01305 ENOG4105C1G acyl-Coa dehydrogenase A320_01306 ENOG4105NIV Esterase A320_01307 ENOG4105CQC Prephenate dehydratase A320_01308 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase A320_01310 ENOG4105CIN aminoacyl-histidine dipeptidase A320_01311 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) A320_01317 ENOG4105M08 Membrane A320_01318 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A320_01320 ENOG4105VEQ Cold shock protein A320_01321 ENOG4105C1J atp-dependent rna helicase A320_01323 ENOG41069NU Nitroreductase A320_01330 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase A320_01333 ENOG4105C5I Dehydrogenase A320_01334 ENOG4105ERG peptidase m48, ste24p A320_01335 ENOG4105KTH gatB Yqey A320_01336 ENOG4105VCC 30S ribosomal protein S21 A320_01341 ENOG4105D9P serine threonine protein kinase A320_01346 ENOG4105EVZ LysR family transcriptional regulator A320_01347 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) A320_01348 ENOG4105C26 Dehydrogenase A320_01355 ENOG4105H4F exported protein A320_01361 ENOG4105D6U Sodium Glutamate Symporter A320_01363 ENOG4105JXH GntR family transcriptional regulator A320_01373 ENOG4105CSH Transporter A320_01376 ENOG4105CEB Aspartate aminotransferase A320_01379 ENOG4105F1S paraquat-inducible protein a A320_01380 ENOG4105DY2 Paraquat-inducible protein b A320_01388 ENOG4105CK2 sodium dicarboxylate symporter A320_01390 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) A320_01391 ENOG4108UMI ABC transporter, permease A320_01392 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) A320_01394 ENOG4105C12 Phosphoribosylglycinamide synthetase A320_01395 ENOG4105DC1 bifunctional purine biosynthesis protein purh A320_01396 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) A320_01406 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) A320_01407 ENOG4105CDU Replicative dna helicase A320_01412 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) A320_01413 ENOG4105CCU oxidase (Subunit III) A320_01414 ENOG4105BZ9 Cytochrome C oxidase, subunit I A320_01415 ENOG4105E2S oxidase) subunit II A320_01420 ENOG4107BJW polysaccharide deacetylase A320_01421 ENOG4105CND Glycosyl transferase, family 2 A320_01422 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD A320_01424 ENOG4105DEN Luciferase family A320_01427 ENOG4105CC0 LysR family Transcriptional regulator A320_01430 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) A320_01431 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component A320_01432 ENOG4105GVF (ABC) transporter A320_01435 ENOG4105C1G acyl-Coa dehydrogenase A320_01437 ENOG4108MEJ flavin reductase domain protein A320_01438 ENOG4105D06 uba thif-type nad fad binding protein A320_01442 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) A320_01443 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) A320_01445 ENOG4105C08 Histidine kinase A320_01446 ENOG4105EEX Two component transcriptional regulator (Winged helix family A320_01447 ENOG4105CFQ glutamine synthetase A320_01450 ENOG4107S74 Lysophospholipid transporter LplT A320_01451 ENOG4105CFU surface antigen A320_01454 ENOG4107QIJ Aconitate hydratase 2 A320_01456 ENOG4105EYW Ion transport protein A320_01457 ENOG4105F27 Major Facilitator A320_01460 ENOG4105DZ2 Transcriptional regulator A320_01467 ENOG4105K8N protein family UPF0079, ATPase A320_01468 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) A320_01470 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) A320_01471 ENOG4108TZV Membrane A320_01472 ENOG4108RCM Nitroreductase A320_01474 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) A320_01477 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) A320_01478 ENOG4107FQ9 ethanolamine ammonia-lyase A320_01479 ENOG4105CPD ethanolamine ammonia-lyase A320_01480 ENOG4107R55 ethanolamine transporter A320_01482 ENOG4107RR1 TRANSCRIPTIONal A320_01484 ENOG4105C0A alcohol dehydrogenase A320_01485 ENOG4107QUV Domain protein A320_01487 ENOG4105F4I Transcriptional regulator A320_01491 ENOG4105CD8 aminopeptidase N A320_01493 ENOG4105EMU Dehydrogenase A320_01495 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) A320_01496 ENOG4105EW9 transcriptional regulator AsnC family A320_01498 ENOG4105R8C Transcriptional regulator A320_01500 ENOG4105CUY Mechanosensitive ion channel A320_01506 ENOG4105CNM Receptor A320_01510 ENOG4105C5H ABC transporter A320_01511 ENOG41081QV Universal stress protein A320_01516 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic A320_01518 ENOG4105DKK Benzoate A320_01519 ENOG4105EW9 transcriptional regulator AsnC family A320_01520 ENOG4108NIW Leucine export protein LeuE A320_01521 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) A320_01522 ENOG4105C5Q Transcriptional regulator A320_01524 ENOG4105CHU acetyl-coa acetyltransferase A320_01525 ENOG4105CHR reductase A320_01530 ENOG4107QMP dna polymerase iii subunits gamma and tau A320_01532 ENOG4105HSS phospholipase C A320_01534 ENOG4105C0A alcohol dehydrogenase A320_01540 ENOG4105CBC glutamate synthase A320_01544 ENOG4105D8G Major Facilitator superfamily A320_01546 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase A320_01547 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein A320_01551 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A320_01553 ENOG4107QZF nitrite reductase NADPH large subunit A320_01554 ENOG4108IFG nitrite reductase, (NAD(P)H) A320_01558 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) A320_01561 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) A320_01562 ENOG4105CVM Molybdenum cofactor synthesis domain protein A320_01564 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A320_01565 ENOG4105T38 integral membrane protein A320_01569 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) A320_01570 ENOG4105CMR udp-glucose 4-epimerase A320_01581 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family A320_01582 ENOG4105CUX Signal transduction histidine kinase A320_01586 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) A320_01587 ENOG4105KNE Phosphatidate cytidylyltransferase A320_01589 ENOG4105DZP Membrane-associated zinc metalloprotease A320_01594 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) A320_01596 ENOG4105Y3E Modulates RecA activity (By similarity) A320_01598 ENOG4105VEJ Heat shock protein A320_01599 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 A320_01604 ENOG4105F7P transcriptional regulator AsnC family A320_01606 ENOG4105C85 amino acid A320_01609 ENOG4105CHH sulfate transporter A320_01610 ENOG4108RAV Conserved protein A320_01611 ENOG4105D8V Glucose sorbosone dehydrogenase A320_01613 ENOG4105BZU Histidine kinase A320_01618 ENOG4105DM4 PTS System A320_01619 ENOG4105DE4 1-phosphofructokinase A320_01620 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) A320_01625 ENOG4105CWM branched-chain amino acid transport system II carrier protein A320_01626 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) A320_01627 ENOG4105CC0 LysR family Transcriptional regulator A320_01629 ENOG4105M2J Glutaredoxin A320_01630 ENOG4105C8Y Acetylornithine aminotransferase A320_01631 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) A320_01636 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) A320_01638 ENOG41068P6 UPF0319 protein A320_01642 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii A320_01643 ENOG4105C4M (Ubiquinol oxidase) subunit I A320_01645 ENOG4105PV3 Inner membrane protein yqiJ A320_01648 ENOG4105E0K tonB-dependent siderophore receptor A320_01650 ENOG4105HDD phospholipase A320_01651 ENOG4105CZN Potassium uptake protein A320_01653 ENOG4105C7B Threonine dehydratase A320_01659 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) A320_01660 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit A320_01662 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) A320_01665 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A320_01674 ENOG4107VMU Membrane A320_01675 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) A320_01677 ENOG4107QP7 CoA-transferase subunit A A320_01678 ENOG4107QNJ CoA-transferase subunit B A320_01679 ENOG4105CHU acetyl-coa acetyltransferase A320_01680 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase A320_01681 ENOG4105F2Z 3-oxoadipate enol-lactonase A320_01682 ENOG4105D2S major facilitator superfamily A320_01683 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase A320_01684 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta A320_01685 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha A320_01686 ENOG4105FF2 Type I DHQase A320_01687 ENOG4106JPM 3-dehydroshikimate dehydratase A320_01688 ENOG4105TW1 Carbohydrate-selective porin OprB A320_01689 ENOG4105DZG Dehydrogenase A320_01691 ENOG4105MD1 YeeE YedE family protein A320_01694 ENOG4107HP6 Transcriptional regulator A320_01695 ENOG4108PTX LysR family Transcriptional regulator A320_01696 ENOG4105C1G acyl-Coa dehydrogenase A320_01701 ENOG4105DNH Major Facilitator A320_01703 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) A320_01707 ENOG4105FUY alpha subunit A320_01709 ENOG4105CHR reductase A320_01713 ENOG4105F11 amine oxidase A320_01715 ENOG4105C26 Dehydrogenase A320_01717 ENOG4105F2Z 3-oxoadipate enol-lactonase A320_01718 ENOG4105CHU acetyl-coa acetyltransferase A320_01719 ENOG4107QNJ CoA-transferase subunit B A320_01720 ENOG4107QP7 CoA-transferase subunit A A320_01722 ENOG4105NN7 muconolactone delta-isomerase A320_01723 ENOG4105DTQ mandelate racemase muconate lactonizing A320_01724 ENOG4108KB2 LysR family Transcriptional regulator A320_01726 ENOG4107EJG GntR family transcriptional regulator A320_01730 ENOG4105CZJ Aldehyde dehydrogenase A320_01734 ENOG4105C1G acyl-Coa dehydrogenase A320_01735 ENOG4105CHR reductase A320_01736 ENOG4108JU7 Transcriptional regulator A320_01738 ENOG41062QD Membrane A320_01741 ENOG4107RGH Aldehyde dehydrogenase A320_01744 ENOG4105CH6 catalase A320_01748 ENOG4105K56 Transcriptional regulator A320_01749 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A320_01751 ENOG4105NAE bifunctional deaminase-reductase domain protein A320_01757 ENOG4107Z3H Transcriptional regulator, TetR family A320_01759 ENOG4105CHJ isochorismatase hydrolase A320_01760 ENOG4105EJC lysr family transcriptional regulator A320_01761 ENOG4105D8V Glucose sorbosone dehydrogenase A320_01762 ENOG4105CKD glutathione-regulated potassium-efflux system protein A320_01764 ENOG4105CH2 amidohydrolase A320_01766 ENOG4105D5K Hemolysin activator protein A320_01767 ENOG4105CKT filamentous hemagglutinin A320_01773 ENOG4105FDP GntR family transcriptional regulator A320_01776 ENOG4106KR7 LysR family Transcriptional regulator A320_01781 ENOG4108JQ1 Dehydrogenase A320_01782 ENOG4105JSC dimethylmenaquinone methyltransferase A320_01786 ENOG4105CW7 secretion protein, HlyD family A320_01789 ENOG4105CZJ Aldehyde dehydrogenase A320_01790 ENOG4105C01 Dihydroxy-acid dehydratase A320_01792 ENOG4105DDW LysR family Transcriptional regulator A320_01793 ENOG4105EXW epimerase dehydratase A320_01795 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase A320_01796 ENOG4105CF7 AraC family transcriptional regulator A320_01799 ENOG4105DQ4 alcohol dehydrogenase A320_01801 ENOG4105EHG Permease protein A320_01802 ENOG4105E0A ABC, transporter A320_01806 ENOG4105C5T Phosphoribosyl pyrophosphate synthase A320_01822 ENOG4108UAJ Transcriptional regulator A320_01830 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) A320_01841 ENOG4108BAS reductase A320_01844 ENOG4108R6W Transcriptional regulator, ARAC family A320_01845 ENOG4108821 RND type efflux pump A320_01846 ENOG4105E0F Histidine kinase A320_01847 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A320_01848 ENOG4105C1P efflux transporter, rnd family, mfp subunit A320_01849 ENOG4105BZS acriflavin resistance protein A320_01850 ENOG4105ENJ RND efflux system, outer membrane lipoprotein A320_01852 ENOG4105CT3 Monooxygenase A320_01856 ENOG4105CJP fad dependent oxidoreductase A320_01860 ENOG4105X0I Fimbrial A320_01870 ENOG4107RZC phospholipase d A320_01874 ENOG4108IGT Dipeptidase A320_01880 ENOG4107T31 5'-nucleotidase A320_01882 ENOG4105WQI isochorismatase A320_01883 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase A320_01884 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) A320_01885 ENOG4105E0C molybdate abc transporter A320_01886 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein A320_01887 ENOG4105F4R Transcriptional regulator mode A320_01888 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit A320_01889 ENOG4108YS2 small subunit A320_01890 ENOG4105F57 Anthranilate dioxygenase reductase A320_01895 ENOG4105CHR reductase A320_01897 ENOG4105D2S major facilitator superfamily A320_01898 ENOG4105CF7 AraC family transcriptional regulator A320_01899 ENOG4105DTD Dehydrogenase A320_01900 ENOG4105CY2 Citrate transporter A320_01902 ENOG4108M0I Transcriptional regulator A320_01904 ENOG4107QNJ CoA-transferase subunit B A320_01905 ENOG4105CRW Short chain fatty acid transporter A320_01906 ENOG4105CHU acetyl-coa acetyltransferase A320_01908 ENOG4107YNJ LysR family Transcriptional regulator A320_01911 ENOG4108IJ0 Aspartate ammonia-lyase A320_01913 ENOG4105CSH Transporter A320_01917 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component A320_01918 ENOG4106FTQ Taurine ABC transporter, periplasmic A320_01921 ENOG4105FDP GntR family transcriptional regulator A320_01923 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) A320_01924 ENOG4105KVH Transcriptional regulator A320_01925 ENOG4105UEI Transcriptional Regulator AraC Family A320_01928 ENOG4108VCT Sulfite exporter TauE/SafE A320_01930 ENOG4107QPB Beta-lactamase domain protein A320_01932 ENOG4105FFC UPF0187 protein A320_01934 ENOG4105CHR reductase A320_01937 ENOG4105CPP Dehydrogenase, E1 component A320_01938 ENOG4107R0V Pyruvate dehydrogenase A320_01939 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) A320_01942 ENOG4105BZU Histidine kinase A320_01944 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) A320_01945 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) A320_01956 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) A320_01959 ENOG4105C28 cystathionine A320_01961 ENOG4105F2W methyltransferase A320_01967 ENOG4105K59 histidine triad (HIT) protein A320_01972 ENOG4107QWP ABC-2 type transporter A320_01973 ENOG4107QWP ABC-2 type transporter A320_01974 ENOG4105CJ1 ABC, transporter A320_01977 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) A320_01978 ENOG4105CNM Receptor A320_01982 ENOG4107TSN permease A320_01983 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) A320_01987 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) A320_01988 ENOG4108YZT Adenosylcobinamide kinase A320_01990 ENOG4107VXZ Hydrolase A320_01998 ENOG4105DJU Siderophore biosynthesis protein A320_01999 ENOG4105DUU IucA IucC family protein A320_02003 ENOG4108Z66 YbaK ebsC protein A320_02006 ENOG4105C1G acyl-Coa dehydrogenase A320_02007 ENOG4105C1G acyl-Coa dehydrogenase A320_02008 ENOG4105EEF Alkane 1-monooxygenase A320_02009 ENOG4105E7U AraC family transcriptional regulator A320_02010 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) A320_02011 ENOG4105K70 DNA-binding protein A320_02014 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family A320_02016 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins A320_02017 ENOG4108Z4V iron-sulfur cluster assembly A320_02020 ENOG4108ZIT Ferredoxin, 2FE-2S A320_02021 ENOG4105F8J Adenylate Guanylate cyclase A320_02023 ENOG4108JA2 transcriptioN-repair coupling factor A320_02027 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) A320_02028 ENOG4105K4T epimerase A320_02031 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase A320_02035 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component A320_02037 ENOG4105DGW oligopeptidase A A320_02045 ENOG4105SG9 biopolymer transport protein, ExbD A320_02047 ENOG4107QP3 malate synthase g A320_02048 ENOG4105D6Z AFG1 family ATPase A320_02050 ENOG4107RN6 Monooxygenase A320_02054 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) A320_02055 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) A320_02058 ENOG4108Z6B deaminase A320_02062 ENOG4108RTD type II secretion system protein K A320_02067 ENOG4105F8V Hydrolase, tatD family A320_02069 ENOG4107QRG dna polymerase iii A320_02071 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) A320_02072 ENOG4105BZ1 (ABC) transporter A320_02075 ENOG4105FA0 parb-like partition protein A320_02076 ENOG4107QJE Chromosome Partitioning Protein A320_02078 ENOG4108S0S Nucleotidyl transferase A320_02079 ENOG4105EHM Aminoglycoside phosphotransferase A320_02080 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) A320_02081 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) A320_02082 ENOG4105D2N Aldolase A320_02086 ENOG4108UHJ MAF-like protein A320_02087 ENOG4105EZE Cupin 4 family protein A320_02089 ENOG41080HT Transcriptional regulator, arsr family A320_02091 ENOG4105XPP Protein of unknown function (DUF1275) A320_02092 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme A320_02093 ENOG4105BZ1 (ABC) transporter A320_02095 ENOG4108ZX5 transcriptional regulator A320_02097 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) A320_02098 ENOG4105CK7 Sodium proline symporter A320_02099 ENOG4105EW9 transcriptional regulator AsnC family A320_02100 ENOG4105C26 Dehydrogenase A320_02101 ENOG4105YGK Pfam:UPF0157 A320_02104 ENOG4108T58 Mg2 transport protein CorA A320_02106 ENOG4108YYC ycei family A320_02108 ENOG4105CV1 Transketolase (EC 2.2.1.1) A320_02113 ENOG4108HWY Beta-lactamase A320_02117 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) A320_02118 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) A320_02122 ENOG4105X0I Fimbrial A320_02123 ENOG4105GQR Chaperone A320_02128 ENOG4108IPJ Membrane A320_02130 ENOG4105ETS cytosine purines uracil thiamine allantoin A320_02132 ENOG4105CC0 LysR family Transcriptional regulator A320_02137 ENOG41067SE Tetr family transcriptional regulator A320_02140 ENOG4105EW9 transcriptional regulator AsnC family A320_02142 ENOG4105CDA abc transporter atp-binding protein A320_02143 ENOG4105DRP amino acid AbC transporter A320_02144 ENOG4105EAD ABC transporter A320_02147 ENOG4107T8P acyl-Coa dehydrogenase A320_02150 ENOG4105D01 (LipO)protein A320_02151 ENOG4105D01 (LipO)protein A320_02152 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) A320_02153 ENOG4108UMI ABC transporter, permease A320_02154 ENOG4105C3G gtp-binding protein A320_02159 ENOG4108UMN azlc family A320_02160 ENOG4105ZED uncharacterized protein ygaH A320_02166 ENOG4105E7U AraC family transcriptional regulator A320_02167 ENOG4108V06 Glutathione peroxidase A320_02169 ENOG4105CHM Aminotransferase A320_02172 ENOG4105C0B DNA polymerase III (alpha subunit) A320_02177 ENOG4108JU3 Alkyl hydroperoxide reductase A320_02180 ENOG4108KB2 LysR family Transcriptional regulator A320_02181 ENOG4105D6J arsenicaL-resistance protein A320_02182 ENOG41082YX Transcriptional regulator, arsr family A320_02185 ENOG4105CPN adenine deaminase A320_02187 ENOG4105CBN LysR family transcriptional regulator A320_02189 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease A320_02191 ENOG4105E2B Taurine dioxygenase A320_02192 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component A320_02193 ENOG4108IY8 ABC, transporter A320_02194 ENOG4106FTQ Taurine ABC transporter, periplasmic A320_02196 ENOG4105C54 Major Facilitator superfamily A320_02200 ENOG4105C4M (Ubiquinol oxidase) subunit I A320_02201 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii A320_02203 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A320_02204 ENOG4108K70 Transcriptional regulator A320_02207 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase A320_02208 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase A320_02211 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) A320_02212 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase A320_02214 ENOG4105DXI Major Facilitator superfamily A320_02218 ENOG41067MG lrgb family A320_02219 ENOG4105VAW lrga family A320_02220 ENOG4105CMU LysR family (Transcriptional regulator A320_02221 ENOG4108SHQ Glutathione S-transferase A320_02222 ENOG4105CYM Glutathione S-transferase A320_02223 ENOG4105CBN LysR family transcriptional regulator A320_02224 ENOG4105CHR reductase A320_02226 ENOG4105D7W serine acetyltransferase A320_02227 ENOG4105ESN nucleotide-binding protein A320_02228 ENOG4105C9B Cysteine desulfurase A320_02230 ENOG4105EXG Transcriptional regulator A320_02231 ENOG4105CT1 (ABC) transporter A320_02232 ENOG4107RP9 extracellular solute-binding protein, family 3 A320_02233 ENOG4105CDA abc transporter atp-binding protein A320_02234 ENOG4108HW4 amino acid AbC transporter A320_02235 ENOG4105EAD ABC transporter A320_02237 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase A320_02238 ENOG4105BZU Histidine kinase A320_02240 ENOG4105EW9 transcriptional regulator AsnC family A320_02242 ENOG4105KT5 UmuD protein A320_02246 ENOG4105CYX Short-chain dehydrogenase reductase Sdr A320_02257 ENOG4105HEI LysR family (Transcriptional regulator A320_02261 ENOG4105CEY Amp-dependent synthetase and ligase A320_02262 ENOG4105R8C Transcriptional regulator A320_02263 ENOG4105C1G acyl-Coa dehydrogenase A320_02264 ENOG4107QX3 carboxylase A320_02265 ENOG4105E39 Enoyl-CoA hydratase A320_02268 ENOG4105CC0 LysR family Transcriptional regulator A320_02271 ENOG4105CSU acyl-Coa dehydrogenase A320_02273 ENOG4105EQ0 Major Facilitator superfamily A320_02275 ENOG4107QNJ CoA-transferase subunit B A320_02276 ENOG4107QP7 CoA-transferase subunit A A320_02277 ENOG4107RGD Major Facilitator superfamily A320_02278 ENOG4105C1G acyl-Coa dehydrogenase A320_02279 ENOG4105E39 Enoyl-CoA hydratase A320_02280 ENOG4105CHR reductase A320_02281 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase A320_02282 ENOG4105CHU acetyl-coa acetyltransferase A320_02284 ENOG4105EQ0 Major Facilitator superfamily A320_02285 ENOG4105EA8 2-Nitropropane dioxygenase A320_02286 ENOG4108UKI Enoyl-CoA hydratase A320_02289 ENOG4105C1G acyl-Coa dehydrogenase A320_02290 ENOG4107RGD Major Facilitator superfamily A320_02291 ENOG4108KAZ Involved in phosphonate degradation (By similarity) A320_02292 ENOG4107STF Involved in phosphonate degradation (By similarity) A320_02294 ENOG4107RCV ABC transporter, permease A320_02295 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) A320_02296 ENOG4105C4Y ABC transporter A320_02298 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase A320_02299 ENOG4107HP6 Transcriptional regulator A320_02301 ENOG4105HEI LysR family (Transcriptional regulator A320_02302 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase A320_02303 ENOG4105C26 Dehydrogenase A320_02305 ENOG4105ETS cytosine purines uracil thiamine allantoin A320_02306 ENOG4105C26 Dehydrogenase A320_02307 ENOG4108M8W Monooxygenase A320_02308 ENOG4105MXW flavin reductase domain protein, FMN-binding A320_02309 ENOG4108MXF Alpha Beta Hydrolase A320_02313 ENOG4105CPW cytochrome b561 A320_02314 ENOG4107VGR Catalase A320_02321 ENOG4107YAU phenylacetic acid degradation protein A320_02323 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein A320_02324 ENOG4105DZS Phenylacetate-CoA ligase A320_02325 ENOG4105CHU acetyl-coa acetyltransferase A320_02326 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase A320_02327 ENOG4108UKI Enoyl-CoA hydratase A320_02328 ENOG4105E39 Enoyl-CoA hydratase A320_02329 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) A320_02330 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit A320_02331 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit A320_02332 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit A320_02333 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit A320_02334 ENOG4105DXM phenylacetic acid degradation protein A320_02335 ENOG4105EJQ L-serine dehydratase A320_02336 ENOG4107QTZ amino acid A320_02337 ENOG4105CZJ Aldehyde dehydrogenase A320_02342 ENOG4105MWK D-amino acid dehydrogenase, small subunit A320_02346 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) A320_02349 ENOG4108Z4X TRANSCRIPTIONal A320_02351 ENOG4105WPN DNA integration recombination invertion protein A320_02354 ENOG4105DJ2 Major Facilitator Superfamily A320_02355 ENOG4107Y2X deaminase A320_02357 ENOG4105EMY transcriptional regulator A320_02363 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit A320_02365 ENOG4105UYK outer membrane protein a A320_02379 ENOG4108HW3 (ABC) transporter A320_02381 ENOG4105MRR Transcriptional regulator (By similarity) A320_02384 ENOG4105KVH Transcriptional regulator A320_02385 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF A320_02386 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase A320_02389 ENOG4105E2A Dehydrogenase A320_02391 ENOG4105R8C Transcriptional regulator A320_02396 ENOG4107R4J Chloride channel A320_02397 ENOG4108JIK carboxylase A320_02401 ENOG4105C5A transporter A320_02402 ENOG4108WAV Transcriptional regulator A320_02405 ENOG4105CNA YD repeat protein A320_02411 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) A320_02415 ENOG4105D2S major facilitator superfamily A320_02417 ENOG4105D1S lipid A biosynthesis A320_02418 ENOG4105BZU Histidine kinase A320_02419 ENOG4107AQZ Membrane A320_02423 ENOG4108Z4U Ferredoxin A320_02431 ENOG4105DFG type I secretion outer membrane protein A320_02432 ENOG4108IUZ ABC transporter A320_02433 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA A320_02435 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase A320_02436 ENOG4105C2X Arabinose 5-phosphate isomerase A320_02443 ENOG4107YPT transcriptional regulator A320_02449 ENOG4105II7 pyrroline-5-carboxylate reductase A320_02451 ENOG4105VEQ Cold shock protein A320_02452 ENOG410829K Lysine exporter protein (Lyse ygga) A320_02459 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) A320_02469 ENOG4108KB2 LysR family Transcriptional regulator A320_02470 ENOG4105FUY alpha subunit A320_02471 ENOG4108UKV benzoate 1,2-dioxygenase A320_02472 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein A320_02473 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase A320_02474 ENOG4105DKK Benzoate A320_02475 ENOG4105D2S major facilitator superfamily A320_02478 ENOG4105CQ7 ATP-dependent helicase A320_02479 ENOG4105D3R alkyl hydroperoxide reductase A320_02481 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) A320_02483 ENOG4108JU3 Alkyl hydroperoxide reductase A320_02485 ENOG4108K3A Glutathione S-transferase A320_02487 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) A320_02488 ENOG4108TGY Glutathione S-transferase A320_02490 ENOG4108ZG0 Ompa motb domain protein A320_02491 ENOG4105CD3 dihydroorotase A320_02497 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit A320_02500 ENOG4108UKZ OsmC family A320_02501 ENOG4107RYR Transcriptional regulator, Crp Fnr family A320_02502 ENOG4105CPC Aldo Keto reductase A320_02505 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis A320_02507 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase A320_02509 ENOG4105CFH Aspartokinase A320_02511 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) A320_02513 ENOG4105CPW cytochrome b561 A320_02514 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) A320_02515 ENOG4105C7N Xanthine uracil vitamin C permease A320_02517 ENOG4105F95 Monooxygenase A320_02524 ENOG4105F95 Monooxygenase A320_02553 ENOG4105NX3 Membrane A320_02556 ENOG4105E4F Isochorismate synthase A320_02560 ENOG4105BZ1 (ABC) transporter A320_02563 ENOG4105WQI isochorismatase A320_02564 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase A320_02565 ENOG4105C0W non-ribosomal peptide synthetase A320_02569 ENOG4108IPW abc transporter atp-binding protein A320_02574 ENOG4105CEY Amp-dependent synthetase and ligase A320_02577 ENOG4105WWK YheO domain protein A320_02580 ENOG4105C2I pirin domain protein A320_02583 ENOG4105J7D transcriptional regulator A320_02585 ENOG4107WEA mandelate racemase muconate lactonizing A320_02586 ENOG4107QNK )-transporter A320_02587 ENOG41060M8 Pfam:PhdYeFM A320_02593 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) A320_02594 ENOG4107QZF nitrite reductase NADPH large subunit A320_02595 ENOG4105C26 Dehydrogenase A320_02597 ENOG4105C94 Transporter A320_02598 ENOG4105C94 Transporter A320_02599 ENOG4105ETT transcriptional Regulator, LysR family A320_02600 ENOG4105C85 amino acid A320_02601 ENOG4105C26 Dehydrogenase A320_02604 ENOG4108K8K Transcriptional regulator A320_02611 ENOG4105VCD cytoplasmic protein A320_02612 ENOG4105D22 carbon starvation protein A320_02614 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein A320_02618 ENOG4105DHU Bile acid A320_02621 ENOG4105DAN ATP-dependent protease A320_02622 ENOG4105EJC lysr family transcriptional regulator A320_02623 ENOG4108K5P (LipO)protein A320_02627 ENOG4105DZ1 carboxypeptidase A320_02628 ENOG4108Z0R Transferase A320_02632 ENOG4107QTF adenylosuccinate lyase A320_02635 ENOG4105ERU peptidase A320_02636 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) A320_02638 ENOG4105C8U phosphate abc transporter A320_02639 ENOG4105CVA phosphate A320_02640 ENOG4105C85 amino acid A320_02641 ENOG4107RA9 decarboxylase A320_02642 ENOG4105F7P transcriptional regulator AsnC family A320_02644 ENOG4105DY8 decarboxylase A320_02645 ENOG4108JPW Aminotransferase A320_02650 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) A320_02653 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) A320_02654 ENOG4105D3G Pseudouridine synthase A320_02657 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) A320_02663 ENOG4105JAB phenazine biosynthesis protein, phzf family A320_02664 ENOG4108ETY sodium dicarboxylate symporter A320_02665 ENOG4105EGI Transcriptional regulator A320_02666 ENOG4105CBP Major Facilitator A320_02670 ENOG4108R99 pseudouridine synthase A320_02671 ENOG4105E9K Isocitrate dehydrogenase A320_02673 ENOG4105DZ1 carboxypeptidase A320_02674 ENOG4105CEP NADH dehydrogenase A320_02675 ENOG4108YZY peptidylprolyl cis-trans isomerase A320_02676 ENOG4105CVP deoxyribo-dipyrimidine photolyase A320_02679 ENOG4107R8N Glycosyl transferase, family 2 A320_02685 ENOG4105EA8 2-Nitropropane dioxygenase A320_02686 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) A320_02756 ENOG4107QS8 (LipO)protein A320_02763 ENOG4105DTR rard protein A320_02765 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) A320_02767 ENOG4105BZU Histidine kinase A320_02774 ENOG4105EMU Dehydrogenase A320_02775 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase A320_02776 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) A320_02777 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) A320_02779 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) A320_02782 ENOG4105C3F Signal peptidase i A320_02785 ENOG4105C0H protease A320_02786 ENOG4108IYU L-aspartate oxidase A320_02789 ENOG4105HHA aminodeoxychorismate lyase A320_02790 ENOG4105YAZ 4-amino-4-deoxychorismate lyase A320_02791 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein A320_02793 ENOG4108I5D sulfate abc transporter A320_02795 ENOG4108IJ6 ABC transporter A320_02796 ENOG4107R11 Transcriptional regulator A320_02799 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) A320_02800 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) A320_02803 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen A320_02806 ENOG4108UKI Enoyl-CoA hydratase A320_02807 ENOG4105EGD dinuclear metal center protein, YbgI family A320_02809 ENOG4105C2C drug resistance transporter, Bcr CflA A320_02810 ENOG4108ETH Formylglycinamide ribotide synthetase A320_02814 ENOG4105CH2 amidohydrolase A320_02815 ENOG4107YD3 Thioesterase A320_02816 ENOG4105E02 MotA TolQ exbB proton channel A320_02817 ENOG4105M8F Biopolymer transport protein exbD tolR A320_02819 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) A320_02820 ENOG4105KCK Peptidoglycan-associated lipoprotein A320_02830 ENOG4105C02 permease A320_02832 ENOG4108V3E phosphoribosylglycinamide formyltransferase A320_02833 ENOG4107R6F Alpha Beta Hydrolase Fold protein A320_02834 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) A320_02836 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 A320_02837 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) A320_02838 ENOG4105D60 lipoprotein releasing system transmembrane protein A320_02845 ENOG4107KET secretion protein, HlyD family A320_02852 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) A320_02853 ENOG4105C10 Electron transfer flavoprotein A320_02854 ENOG4105BZJ Electron transfer flavoprotein A320_02855 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) A320_02856 ENOG4105N14 lysine exporter protein LysE YggA A320_02858 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) A320_02860 ENOG4105C85 amino acid A320_02861 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) A320_02863 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) A320_02866 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) A320_02867 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit A320_02868 ENOG4105BZW Glycerate kinase A320_02876 ENOG4105CEY Amp-dependent synthetase and ligase A320_02879 ENOG4108RRZ Transcription elongation factor GreB A320_02883 ENOG4105E4C Lytic transglycosylase catalytic A320_02886 ENOG4105BZS acriflavin resistance protein A320_02887 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase A320_02889 ENOG41080IJ Diacylglycerol kinase A320_02893 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) A320_02896 ENOG4105C6V Glycerol-3-phosphate dehydrogenase A320_02897 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) A320_02898 ENOG4105CSH Transporter A320_02908 ENOG4105EEI dihydropteroate synthase A320_02909 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) A320_02911 ENOG4105HBR Rna-binding protein A320_02914 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain A320_02915 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain A320_02918 ENOG41080TK Universal stress protein A320_02921 ENOG4105PNM synthesis protein A320_02924 ENOG4105EEQ Na H antiporter A320_02925 ENOG4105CGZ zinc metallopeptidase A320_02926 ENOG4105CKW Inner membrane protein yedI A320_02928 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha A320_02930 ENOG4107QN2 dihydrolipoyl dehydrogenase A320_02931 ENOG4105C7S Dehydrogenase A320_02932 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 A320_02933 ENOG4105E33 succinate dehydrogenase A320_02935 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein A320_02936 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit A320_02943 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A320_02944 ENOG41084BA UPF0250 protein A320_02945 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) A320_02948 ENOG4105CUB amino acid A320_02950 ENOG4105KVH Transcriptional regulator A320_02951 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) A320_02952 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) A320_02955 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) A320_02960 ENOG410841Q phosphoesterase PA-phosphatase related protein A320_02961 ENOG4105C1P efflux transporter, rnd family, mfp subunit A320_02962 ENOG4105BZS acriflavin resistance protein A320_02963 ENOG4105ENJ RND efflux system, outer membrane lipoprotein A320_02964 ENOG4105K8R UPF0145 protein A320_02965 ENOG4105K8R UPF0145 protein A320_02969 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) A320_02973 ENOG4108M0I Transcriptional regulator A320_02976 ENOG4105DHQ Histidine kinase A320_02977 ENOG4105XJC Two component transcriptional regulator (Winged helix family A320_02978 ENOG4105DIJ Phosphoethanolamine transferase A320_02982 ENOG4105D78 K07001 NTE family protein A320_02985 ENOG4105MSB protein, conserved in bacteria A320_02986 ENOG4105CTB Polyprenyl synthetase A320_02987 ENOG4105C7F AcnD-accessory protein PrpF A320_02988 ENOG4105C85 amino acid A320_02992 ENOG4105CF7 AraC family transcriptional regulator A320_02997 ENOG4108X0B nad(p)h dehydrogenase (quinone) A320_02999 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein A320_03001 ENOG4105D8T Acyltransferase A320_03003 ENOG4105C03 ribonuclease A320_03004 ENOG4108Z03 MAF-like protein A320_03005 ENOG4105VQ7 Rod shape-determining protein MreD A320_03006 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) A320_03007 ENOG4105DFF Rod shape-determining protein mreb A320_03008 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) A320_03010 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) A320_03017 ENOG4105C7B Threonine dehydratase A320_03018 ENOG4105D78 K07001 NTE family protein A320_03019 ENOG4105BZG amino acid carrier protein A320_03022 ENOG4105C2C drug resistance transporter, Bcr CflA A320_03023 ENOG4105EM2 membrane A320_03025 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) A320_03033 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein A320_03034 ENOG4105WD1 Membrane A320_03036 ENOG4106HKS Entericidin EcnA/B family A320_03039 ENOG4105CBS Chea signal transduction histidine kinase A320_03040 ENOG4105C8Q Methyl-accepting chemotaxis A320_03041 ENOG4108ZGA chew protein A320_03042 ENOG4105M3Z response regulator A320_03043 ENOG4108UNF response regulator A320_03048 ENOG4105KWI UPF0339 protein A320_03049 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA A320_03050 ENOG4105K78 MarR family Transcriptional regulator A320_03052 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) A320_03053 ENOG4105T95 Thiol disulfide interChange protein A320_03055 ENOG4108N2Y auxin Efflux A320_03056 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A320_03057 ENOG4105CHB tonB-dependent Receptor A320_03058 ENOG4108VX5 3-methyladenine DNA glycosylase A320_03060 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) A320_03064 ENOG4105C2W permease A320_03066 ENOG4108IQI permease A320_03067 ENOG4105E0Y RtcB Protein A320_03069 ENOG4108WHA ompa motb domain protein A320_03071 ENOG4105CHU acetyl-coa acetyltransferase A320_03073 ENOG410814C multidrug resistance protein A320_03075 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) A320_03076 ENOG4105DZG Dehydrogenase A320_03077 ENOG4105TW1 Carbohydrate-selective porin OprB A320_03079 ENOG4108R6W Transcriptional regulator, ARAC family A320_03080 ENOG4105CHU acetyl-coa acetyltransferase A320_03087 ENOG4108UT2 hemolysin iii A320_03088 ENOG4105CSH Transporter A320_03091 ENOG4105D3R alkyl hydroperoxide reductase A320_03095 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase A320_03102 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) A320_03105 ENOG4108WBT adenosyltransferase A320_03109 ENOG4105CNG UPF0061 protein A320_03110 ENOG4105E3W Two component transcriptional regulator (Winged helix family A320_03111 ENOG4105EB3 Histidine kinase A320_03113 ENOG4105CSU acyl-Coa dehydrogenase A320_03114 ENOG4105CSU acyl-Coa dehydrogenase A320_03115 ENOG4108R4R Iron-regulated virulence regulatory protein A320_03116 ENOG4108K3A Glutathione S-transferase A320_03117 ENOG4108VY7 phosphate-starvation-inducible protein PsiE A320_03121 ENOG4105UGU tonB-dependent Receptor A320_03129 ENOG4108PQP glycosyl transferase group 1 A320_03131 ENOG4107BJW polysaccharide deacetylase A320_03134 ENOG4105CM2 brancheD-chain amino acid aminotransferase A320_03135 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) A320_03136 ENOG4105BZU Histidine kinase A320_03145 ENOG4105VIE preprotein translocase, subunit YajC A320_03146 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) A320_03147 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) A320_03148 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase A320_03150 ENOG4105FFC UPF0187 protein A320_03151 ENOG4105DB7 PHP domain protein A320_03153 ENOG4105K9H YciI-like protein A320_03159 ENOG4105NAU thioesterase Superfamily protein A320_03161 ENOG4107U2T alpha beta A320_03162 ENOG4107QPB Beta-lactamase domain protein A320_03164 ENOG4107QN2 dihydrolipoyl dehydrogenase A320_03171 ENOG4108KHX Diguanylate cyclase A320_03172 ENOG4105UYK outer membrane protein a A320_03174 ENOG4107RZC phospholipase d A320_03176 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) A320_03180 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) A320_03181 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) A320_03182 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) A320_03184 ENOG4108UJD 30S ribosomal protein S9 A320_03185 ENOG4107MKT Stringent starvation protein a A320_03186 ENOG4105KB2 stringent starvation protein b A320_03190 ENOG4105C1G acyl-Coa dehydrogenase A320_03191 ENOG4107QX3 carboxylase A320_03194 ENOG4108RZE Tetr family transcriptional regulator A320_03195 ENOG4105C1G acyl-Coa dehydrogenase A320_03204 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase A320_03205 ENOG4105D6S protein involved in catabolism of external DNA A320_03211 ENOG4105E4C Lytic transglycosylase catalytic A320_03213 ENOG4105C9A Phoh family A320_03219 ENOG4105CS1 NAD(P)H quinone oxidoreductase A320_03220 ENOG4107S2Z UPF0761 membrane protein A320_03222 ENOG4108K2B transcriptional regulator A320_03223 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase A320_03232 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) A320_03233 ENOG4105DGW oligopeptidase A A320_03234 ENOG4105VKU nucleicacid-binding protein A320_03242 ENOG4105C1G acyl-Coa dehydrogenase A320_03247 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) A320_03249 ENOG41067V7 50S ribosomal protein L36 A320_03250 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) A320_03272 ENOG41089BK Glutamine amido-transferase A320_03273 ENOG4105C28 cystathionine A320_03274 ENOG4105D7A ATP-binding protein A320_03276 ENOG4105KPV Transcriptional regulator A320_03279 ENOG4105CK2 sodium dicarboxylate symporter A320_03280 ENOG4105C29 acyl-CoA thioesterase A320_03284 ENOG4105CB5 ATP-dependent DNA helicase recG A320_03285 ENOG4105MJ2 Competence protein A320_03287 ENOG4108URH decarboxylase A320_03288 ENOG4105D7N magnesium and cobalt transport protein CorA A320_03290 ENOG4105E3I toluene tolerance A320_03292 ENOG4105CY3 ABC transporter, permease A320_03293 ENOG4105DHJ ABC, transporter A320_03294 ENOG4105C1J atp-dependent rna helicase A320_03295 ENOG4105ECY inositol monophosphatase A320_03298 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) A320_03301 ENOG4105CSU acyl-Coa dehydrogenase A320_03303 ENOG41067S9 phage shock protein C, PspC A320_03304 ENOG4105W87 Cbs domain A320_03316 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin A320_03321 ENOG4105C26 Dehydrogenase A320_03323 ENOG4105C8Y Acetylornithine aminotransferase A320_03324 ENOG4105D82 Glutamate dehydrogenase A320_03325 ENOG4108IQI permease A320_03332 ENOG4105IPI Membrane A320_03333 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) A320_03334 ENOG4105EM2 membrane A320_03335 ENOG4107QF7 multi-drug A320_03337 ENOG4105NF4 modulator of drug activity A320_03338 ENOG4105VRH Antibiotic biosynthesis monooxygenase A320_03340 ENOG4105CQB FAD linked oxidase domain protein A320_03341 ENOG4108JQ1 Dehydrogenase A320_03346 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) A320_03347 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) A320_03348 ENOG4107IFA Lipase (EC 3.1.1.3) A320_03351 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) A320_03361 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) A320_03363 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) A320_03364 ENOG4105KME endoribonuclease L-psp A320_03366 ENOG4108UQY Iron-storage protein A320_03367 ENOG4108YSG O-Antigen polymerase A320_03371 ENOG4105HA9 of methanol dehydrogenase type A320_03372 ENOG4108V0P LemA family A320_03374 ENOG4105BZ8 glutamate synthase A320_03375 ENOG4105CBC glutamate synthase A320_03379 ENOG4105E4G Type IV pilus A320_03384 ENOG4108JQC penicillin-binding protein 1A A320_03385 ENOG4105DHI Methyltransferase A320_03388 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) A320_03389 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) A320_03390 ENOG4105CJN penicillin-binding protein A320_03393 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein A320_03398 ENOG4108IQI permease A320_03411 ENOG4105C5H ABC transporter A320_03413 ENOG4105PDP Short chain dehydrogenase A320_03414 ENOG4105CHH sulfate transporter A320_03416 ENOG4105DPZ Two component transcriptional regulator (Winged helix family A320_03417 ENOG4105E0F Histidine kinase A320_03418 ENOG4105CYC Transferase A320_03424 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) A320_03432 ENOG4105CUV Homoserine Kinase A320_03443 ENOG4108UQN AraC family transcriptional regulator A320_03444 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain A320_03447 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein A320_03448 ENOG4105KVH Transcriptional regulator A320_03452 ENOG4105KVH Transcriptional regulator A320_03455 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) A320_03456 ENOG4105CPC Aldo Keto reductase A320_03461 ENOG4106NZI LysR family Transcriptional regulator A320_03462 ENOG4105D94 Major Facilitator Superfamily A320_03468 ENOG4105EUB pirin domain protein A320_03469 ENOG4105CHJ isochorismatase hydrolase A320_03471 ENOG4105C26 Dehydrogenase A320_03472 ENOG4108JPW Aminotransferase A320_03474 ENOG4105C85 amino acid A320_03476 ENOG4108UMN azlc family A320_03478 ENOG4108UUM single-stranded DNA-binding protein A320_03479 ENOG4107RDB Major Facilitator A320_03481 ENOG4105DWF phosphomethylpyrimidine kinase A320_03482 ENOG4105RA2 Membrane A320_03484 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein A320_03485 ENOG4108WUH Transcriptional regulator, TetR family A320_03486 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) A320_03487 ENOG4105BZU Histidine kinase A320_03489 ENOG4105C94 Transporter A320_03491 ENOG4107QN1 sodium solute A320_03492 ENOG41062QD Membrane A320_03493 ENOG4105BZU Histidine kinase A320_03496 ENOG4108UZX fmn reductase A320_03497 ENOG4105FBW Monooxygenase A320_03499 ENOG4108W2Y isochorismatase A320_03500 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) A320_03502 ENOG4105D64 Mechanosensitive ion channel A320_03504 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase A320_03505 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A320_03508 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) A320_03510 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) A320_03513 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) A320_03516 ENOG4105E0K tonB-dependent siderophore receptor A320_03519 ENOG4107QSN dihydrolipoamide acetyltransferase A320_03520 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) A320_03521 ENOG41063SB peptidase A320_03524 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) A320_03525 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) A320_03526 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) A320_03530 ENOG4105D7Z glutathione synthase A320_03534 ENOG4105CGK Exodeoxyribonuclease III A320_03535 ENOG4105KUZ arsenate reductase A320_03539 ENOG4105BZU Histidine kinase A320_03540 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) A320_03549 ENOG41061H0 Monooxygenase A320_03551 ENOG4108Z2U ureidoglycolate hydrolase A320_03552 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) A320_03553 ENOG4105IPS esterase A320_03558 ENOG4105NVB glycoside hydrolase, family 19 A320_03559 ENOG4105CS6 Rhs element vgr protein A320_03561 ENOG4105D9M gamma-glutamylcysteine synthetase A320_03564 ENOG4106BRA Membrane A320_03565 ENOG4105CHM Aminotransferase A320_03566 ENOG4107QJQ Mate efflux family protein A320_03569 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A320_03570 ENOG4105BZU Histidine kinase A320_03573 ENOG4107SCA Formamidase (EC 3.5.1.49) A320_03575 ENOG4105KHC sulfurtransferase A320_03584 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) A320_03587 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) A320_03588 ENOG4108ZAI phosphatidylglycerophosphatase a A320_03590 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) A320_03591 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) A320_03592 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 A320_03594 ENOG41088SP formiminoglutamate hydrolase A320_03596 ENOG4105C85 amino acid A320_03599 ENOG41090B9 response to stress A320_03600 ENOG4105CZE histidine utilization repressor A320_03602 ENOG4105CKI cobalamin synthesis protein A320_03604 ENOG4105C85 amino acid A320_03606 ENOG4108RXX maleylacetoacetate isomerase A320_03610 ENOG4105EWC Purine nucleoside phosphorylase A320_03611 ENOG4107QI1 Mate efflux family protein A320_03612 ENOG4105C09 Bile acid A320_03613 ENOG4108RWI nicotinamidase A320_03614 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) A320_03618 ENOG4105S64 Formate nitrite transporter A320_03619 ENOG4105D1H recombination factor protein RarA A320_03621 ENOG4108ZZ3 UPF0260 protein A320_03625 ENOG4105CEN a g-specific adenine glycosylase A320_03628 ENOG4108R3E Dna-3-methyladenine glycosylase i A320_03629 ENOG4105DQ4 alcohol dehydrogenase A320_03632 ENOG4105HEI LysR family (Transcriptional regulator A320_03633 ENOG4105CV8 reductase A320_03634 ENOG4105F27 Major Facilitator A320_03641 ENOG4105DJY efflux transporter, rnd family, mfp subunit A320_03642 ENOG4108IG5 Transcriptional regulator A320_03644 ENOG4105C2W permease A320_03650 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B A320_03652 ENOG4105C8J )-transporter