locus-tag	class	description
A320_00001	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A320_00002	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A320_00003	COG0596	Alpha beta hydrolase
A320_00008	COG0488	(ABC) transporter
A320_00009	COG0586	Pfam SNARE associated Golgi protein
A320_00011	COG0187	DNA topoisomerase II activity
A320_00013	COG0592	DNA-directed DNA polymerase activity
A320_00015	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A320_00018	COG0706	membrane insertase activity
A320_00021	COG1230	cation diffusion facilitator family transporter
A320_00022	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A320_00026	COG0402	S-adenosylhomocysteine deaminase activity
A320_00028	COG0754	glutathionylspermidine amidase activity
A320_00031	COG0861	Integral membrane protein TerC family
A320_00032	COG0671	phosphoesterase, PA-phosphatase related
A320_00034	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A320_00037	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A320_00038	COG2951	lytic endotransglycosylase activity
A320_00044	COG0583	DNA-binding transcription factor activity
A320_00049	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A320_00057	COG1047	Peptidyl-prolyl cis-trans
A320_00059	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A320_00060	COG0196	riboflavin kinase activity
A320_00062	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A320_00063	COG1309	transcriptional regulator
A320_00064	COG1116	anion transmembrane transporter activity
A320_00065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A320_00066	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A320_00067	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A320_00068	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A320_00072	COG1028	Short-chain dehydrogenase reductase Sdr
A320_00073	COG0546	phosphoglycolate phosphatase activity
A320_00084	COG3023	N-Acetylmuramoyl-L-alanine amidase
A320_00085	COG0728	peptidoglycan biosynthetic process
A320_00090	COG1596	polysaccharide export
A320_00091	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A320_00102	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A320_00103	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A320_00104	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A320_00107	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A320_00108	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A320_00110	COG2186	Transcriptional regulator
A320_00112	COG0277	FAD linked oxidase domain protein
A320_00113	COG1448	Aminotransferase
A320_00114	COG1802	Transcriptional regulator
A320_00117	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A320_00120	COG1051	belongs to the nudix hydrolase family
A320_00125	COG0564	pseudouridine synthase activity
A320_00130	COG1522	sequence-specific DNA binding
A320_00133	COG0251	oxidation-reduction process
A320_00134	COG1113	amino acid transport
A320_00135	COG1113	amino acid transport
A320_00139	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A320_00140	COG1960	acyl-CoA dehydrogenase activity
A320_00141	COG1024	Enoyl-CoA hydratase
A320_00142	COG1024	Enoyl-CoA hydratase
A320_00143	COG0477	Major facilitator Superfamily
A320_00144	COG3916	Acyl-homoserine-lactone synthase
A320_00146	COG2197	response regulator
A320_00148	COG1960	acyl-CoA dehydrogenase activity
A320_00149	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A320_00149	COG3321	synthase
A320_00149	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A320_00149	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A320_00153	COG2267	carboxylic ester hydrolase activity
A320_00157	COG0271	Belongs to the BolA IbaG family
A320_00159	COG1192	Involved in chromosome partitioning
A320_00162	COG0586	Pfam SNARE associated Golgi protein
A320_00163	COG2259	Doxx family
A320_00164	COG4399	Belongs to the UPF0754 family
A320_00165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A320_00165	COG0519	Catalyzes the synthesis of GMP from XMP
A320_00174	COG0281	malic enzyme
A320_00176	COG2837	iron assimilation
A320_00177	COG1280	lysine exporter protein (LysE YggA)
A320_00178	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A320_00179	COG1121	(ABC) transporter
A320_00192	COG0386	Belongs to the glutathione peroxidase family
A320_00195	COG1309	transcriptional regulator
A320_00196	COG0697	spore germination
A320_00198	COG0758	DNA mediated transformation
A320_00205	COG1309	transcriptional regulator
A320_00212	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A320_00214	COG0655	NAD(P)H dehydrogenase (quinone) activity
A320_00224	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A320_00226	COG2814	Major facilitator Superfamily
A320_00228	COG1253	flavin adenine dinucleotide binding
A320_00230	COG2860	membrane
A320_00231	COG0477	Major facilitator Superfamily
A320_00233	COG0318	PFAM AMP-dependent synthetase and ligase
A320_00236	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A320_00240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A320_00242	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A320_00249	COG0589	response to stress
A320_00250	COG0659	secondary active sulfate transmembrane transporter activity
A320_00262	COG0347	Belongs to the P(II) protein family
A320_00263	COG0004	ammonium transporteR
A320_00265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A320_00265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A320_00273	COG0795	lipopolysaccharide-transporting ATPase activity
A320_00274	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A320_00275	COG0793	Belongs to the peptidase S41A family
A320_00278	COG2197	response regulator
A320_00280	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A320_00282	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A320_00283	COG4974	Belongs to the 'phage' integrase family
A320_00288	COG0772	Belongs to the SEDS family
A320_00289	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A320_00290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A320_00291	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A320_00296	COG0697	spore germination
A320_00297	COG1538	Outer membrane efflux protein
A320_00301	COG3275	phosphorelay sensor kinase activity
A320_00303	COG0181	hydroxymethylbilane synthase activity
A320_00312	COG1716	ATPase activity
A320_00313	COG0546	phosphoglycolate phosphatase activity
A320_00332	COG0596	Alpha beta hydrolase
A320_00333	COG2056	Na+-H+ antiporter family
A320_00336	COG0326	Molecular chaperone. Has ATPase activity
A320_00339	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A320_00353	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A320_00354	COG2169	Transcriptional regulator
A320_00354	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A320_00360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A320_00362	COG0497	DNA recombination
A320_00365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A320_00367	COG0237	dephospho-CoA kinase activity
A320_00377	COG0195	Participates in both transcription termination and antitermination
A320_00381	COG2212	antiporter activity
A320_00383	COG0651	ATP synthesis coupled electron transport
A320_00384	COG1006	Multisubunit Na H antiporter MnhC subunit
A320_00385	COG2111	Na H antiporter
A320_00385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A320_00388	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A320_00389	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A320_00392	COG2226	methyltransferase
A320_00396	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A320_00397	COG1074	ATP-dependent DNA helicase activity
A320_00398	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A320_00402	COG0598	Magnesium transport protein CorA
A320_00403	COG0789	Transcriptional regulator
A320_00404	COG0484	heat shock protein binding
A320_00406	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A320_00407	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A320_00407	COG0475	glutathione-regulated potassium exporter activity
A320_00408	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A320_00412	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A320_00414	COG4535	Mg2 and Co2 transporter CorC
A320_00415	COG0425	Belongs to the sulfur carrier protein TusA family
A320_00416	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A320_00416	COG0644	oxidoreductase
A320_00418	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A320_00421	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A320_00422	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
A320_00429	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A320_00432	COG0534	Mate efflux family protein
A320_00434	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A320_00435	COG4221	oxidoreductase activity
A320_00436	COG0583	DNA-binding transcription factor activity
A320_00440	COG1530	ribonuclease E activity
A320_00442	COG0546	phosphoglycolate phosphatase activity
A320_00443	COG2378	regulation of single-species biofilm formation
A320_00444	COG0625	glutathione transferase activity
A320_00446	COG0583	DNA-binding transcription factor activity
A320_00459	COG0473	3-isopropylmalate dehydrogenase activity
A320_00470	COG1301	dicarboxylic acid transport
A320_00472	COG1560	Kdo2-lipid A biosynthetic process
A320_00473	COG1280	lysine exporter protein (LysE YggA)
A320_00477	COG1733	regulation of RNA biosynthetic process
A320_00482	COG0210	DNA helicase
A320_00483	COG0724	RNA recognition motif
A320_00487	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A320_00487	COG4651	solute:proton antiporter activity
A320_00488	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A320_00489	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A320_00492	COG0788	formyltetrahydrofolate deformylase activity
A320_00512	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A320_00512	COG2813	Specifically methylates the guanine in position
A320_00514	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A320_00516	COG4774	siderophore transport
A320_00518	COG0740	serine-type endopeptidase activity
A320_00522	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A320_00522	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A320_00523	COG0280	phosphate acetyltransferase
A320_00523	COG0857	belongs to the CobB CobQ family
A320_00524	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A320_00526	COG0800	Aldolase
A320_00528	COG3265	gluconokinase activity
A320_00529	COG1012	belongs to the aldehyde dehydrogenase family
A320_00531	COG2267	carboxylic ester hydrolase activity
A320_00534	COG0793	Belongs to the peptidase S41A family
A320_00541	COG1426	Protein conserved in bacteria
A320_00549	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A320_00550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A320_00552	COG0318	PFAM AMP-dependent synthetase and ligase
A320_00555	COG2986	histidine ammonia-lyase
A320_00563	COG1028	Short-chain dehydrogenase reductase Sdr
A320_00564	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A320_00568	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A320_00570	COG1162	GTPase activity
A320_00571	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A320_00574	COG1538	Outer membrane efflux protein
A320_00575	COG0577	efflux transmembrane transporter activity
A320_00575	COG1136	(ABC) transporter
A320_00576	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A320_00581	COG0028	Belongs to the TPP enzyme family
A320_00582	COG0440	acetolactate synthase activity
A320_00588	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A320_00591	COG0084	hydrolase, TatD family'
A320_00594	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A320_00595	COG0583	DNA-binding transcription factor activity
A320_00597	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A320_00598	COG2814	Major facilitator Superfamily
A320_00600	COG0697	spore germination
A320_00601	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A320_00602	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A320_00603	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A320_00606	COG3622	Belongs to the hyi family
A320_00607	COG2084	Dehydrogenase
A320_00608	COG1024	Enoyl-CoA hydratase
A320_00609	COG5002	protein histidine kinase activity
A320_00609	COG0784	Response regulator, receiver
A320_00609	COG2205	protein histidine kinase activity
A320_00613	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A320_00615	COG3956	TIGRFAM MazG family protein
A320_00616	COG1555	photosystem II stabilization
A320_00617	COG0617	tRNA 3'-terminal CCA addition
A320_00618	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A320_00622	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A320_00623	COG3028	Belongs to the UPF0307 family
A320_00624	COG0318	PFAM AMP-dependent synthetase and ligase
A320_00627	COG0625	glutathione transferase activity
A320_00628	COG1238	metal cluster binding
A320_00631	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A320_00636	COG0072	phenylalanine-tRNA ligase activity
A320_00641	COG0248	Ppx GppA phosphatase
A320_00643	COG0037	tRNA processing
A320_00651	COG1764	response to oxidative stress
A320_00652	COG1846	Transcriptional regulator
A320_00654	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A320_00666	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A320_00667	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A320_00668	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A320_00670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A320_00681	COG1214	PFAM Peptidase M22, glycoprotease
A320_00686	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A320_00687	COG0561	phosphatase activity
A320_00689	COG2132	Multicopper oxidase
A320_00690	COG3667	copper resistance
A320_00693	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A320_00694	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A320_00695	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A320_00701	COG1063	alcohol dehydrogenase
A320_00702	COG0583	DNA-binding transcription factor activity
A320_00703	COG1960	acyl-CoA dehydrogenase activity
A320_00704	COG2814	Major facilitator Superfamily
A320_00705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A320_00707	COG1053	succinate dehydrogenase
A320_00708	COG0583	DNA-binding transcription factor activity
A320_00711	COG0583	DNA-binding transcription factor activity
A320_00713	COG1473	amidohydrolase
A320_00717	COG0583	DNA-binding transcription factor activity
A320_00719	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A320_00720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A320_00725	COG0384	phenazine biosynthesis protein PhzF
A320_00729	COG4993	Dehydrogenase
A320_00743	COG2205	protein histidine kinase activity
A320_00744	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A320_00747	COG0745	RESPONSE REGULATOR receiver
A320_00748	COG2205	protein histidine kinase activity
A320_00755	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A320_00761	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A320_00762	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A320_00766	COG0583	DNA-binding transcription factor activity
A320_00770	COG0668	transmembrane transport
A320_00772	COG2081	HI0933 family
A320_00773	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A320_00779	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A320_00779	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A320_00781	COG0489	protein tyrosine kinase activity
A320_00791	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A320_00793	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A320_00796	COG0730	response to heat
A320_00798	COG1196	nuclear chromosome segregation
A320_00802	COG2223	nitrite transmembrane transporter activity
A320_00803	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A320_00804	COG1877	trehalose-phosphatase activity
A320_00805	COG0596	Alpha beta hydrolase
A320_00805	COG2226	methyltransferase
A320_00805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A320_00808	COG4106	trans-aconitate 2-methyltransferase activity
A320_00811	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A320_00812	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A320_00813	COG0009	L-threonylcarbamoyladenylate synthase
A320_00814	COG3101	peptidyl-lysine hydroxylation
A320_00815	COG1399	metal-binding, possibly nucleic acid-binding protein
A320_00820	COG1652	LysM domain
A320_00821	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A320_00821	COG0352	thiamine-phosphate diphosphorylase activity
A320_00821	COG0351	phosphomethylpyrimidine kinase
A320_00823	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A320_00829	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A320_00834	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
A320_00837	COG0358	DNA primase activity
A320_00839	COG0564	pseudouridine synthase activity
A320_00844	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A320_00847	COG0583	DNA-binding transcription factor activity
A320_00848	COG0473	3-isopropylmalate dehydrogenase activity
A320_00852	COG1012	belongs to the aldehyde dehydrogenase family
A320_00856	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A320_00856	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A320_00868	COG0456	acetyltransferase
A320_00870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A320_00871	COG0492	ferredoxin-NADP+ reductase activity
A320_00872	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A320_00872	COG1674	ftsk spoiiie
A320_00873	COG1280	lysine exporter protein (LysE YggA)
A320_00878	COG2894	cell division
A320_00881	COG0204	Acyl-transferase
A320_00882	COG2885	chlorophyll binding
A320_00884	COG0210	DNA helicase
A320_00886	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A320_00889	COG0121	glutamine amidotransferase
A320_00893	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A320_00894	COG0735	belongs to the Fur family
A320_00899	COG0420	3'-5' exonuclease activity
A320_00903	COG1090	epimerase
A320_00906	COG2050	protein possibly involved in aromatic compounds catabolism
A320_00908	COG2814	Major facilitator Superfamily
A320_00909	COG0405	Gamma-glutamyltransferase
A320_00917	COG0477	Major facilitator Superfamily
A320_00918	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A320_00923	COG0531	amino acid
A320_00924	COG2040	homocysteine
A320_00929	COG1309	transcriptional regulator
A320_00930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A320_00931	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A320_00933	COG1607	acyl-coa hydrolase
A320_00935	COG0523	cobalamin synthesis protein
A320_00937	COG4681	YaeQ
A320_00939	COG1649	PFAM Uncharacterised BCR, COG1649
A320_00939	COG0726	polysaccharide deacetylase
A320_00940	COG1215	transferase activity, transferring glycosyl groups
A320_00942	COG1024	Enoyl-CoA hydratase
A320_00945	COG1414	Transcriptional regulator
A320_00949	COG1028	Short-chain dehydrogenase reductase Sdr
A320_00951	COG0446	pyridine nucleotide-disulphide oxidoreductase
A320_00952	COG2271	Major facilitator Superfamily
A320_00954	COG2267	carboxylic ester hydrolase activity
A320_00955	COG1028	Short-chain dehydrogenase reductase Sdr
A320_00958	COG0028	Belongs to the TPP enzyme family
A320_00960	COG0477	Major facilitator Superfamily
A320_00962	COG0242	peptide deformylase activity
A320_00963	COG2066	Belongs to the glutaminase family
A320_00964	COG2207	Transcriptional regulator
A320_00965	COG2223	nitrite transmembrane transporter activity
A320_00968	COG0583	DNA-binding transcription factor activity
A320_00969	COG1028	Short-chain dehydrogenase reductase Sdr
A320_00970	COG2271	Major facilitator Superfamily
A320_00971	COG3959	Transketolase, thiamine diphosphate binding domain
A320_00972	COG3958	Transketolase
A320_00974	COG0306	phosphate transporter
A320_00978	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A320_00987	COG4181	ATPase activity
A320_00988	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A320_00993	COG0583	DNA-binding transcription factor activity
A320_00995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A320_00996	COG1773	rubredoxin
A320_01006	COG2851	Citrate transporter
A320_01007	COG1253	flavin adenine dinucleotide binding
A320_01015	COG0804	urea catabolic process
A320_01016	COG0804	urea catabolic process
A320_01018	COG0830	nickel cation binding
A320_01021	COG0742	ribosomal rna small subunit methyltransferase
A320_01022	COG0768	penicillin binding
A320_01026	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A320_01027	COG2878	Part of a membrane complex involved in electron transport
A320_01028	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A320_01030	COG3384	dioxygenase
A320_01035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A320_01099	COG0739	heme binding
A320_01108	COG2194	sulfuric ester hydrolase activity
A320_01115	COG0006	proline dipeptidase activity
A320_01116	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A320_01117	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A320_01121	COG1279	arginine transmembrane transporter activity
A320_01122	COG0583	DNA-binding transcription factor activity
A320_01130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A320_01131	COG1388	LysM domain
A320_01131	COG0741	lytic transglycosylase activity
A320_01131	COG1388	LysM domain
A320_01131	COG0741	lytic transglycosylase activity
A320_01133	COG4174	ABC transporter (Permease)
A320_01134	COG4239	(ABC) transporter, permease
A320_01135	COG4172	Belongs to the ABC transporter superfamily
A320_01139	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A320_01141	COG5001	Diguanylate cyclase
A320_01141	COG2203	Gaf domain
A320_01141	COG4251	negative regulation of phosphorylation
A320_01141	COG3706	GGDEF domain
A320_01143	COG0446	pyridine nucleotide-disulphide oxidoreductase
A320_01143	COG1902	pentaerythritol trinitrate reductase activity
A320_01146	COG4269	membrane
A320_01150	COG3501	Rhs element vgr protein
A320_01151	COG3209	COG3209 Rhs family protein
A320_01159	COG1113	amino acid transport
A320_01161	COG0531	amino acid
A320_01165	COG1012	belongs to the aldehyde dehydrogenase family
A320_01169	COG1113	amino acid transport
A320_01172	COG0697	spore germination
A320_01173	COG2721	sulfolactate sulfo-lyase activity
A320_01174	COG2271	Major facilitator Superfamily
A320_01175	COG4948	Mandelate Racemase Muconate Lactonizing
A320_01177	COG1012	belongs to the aldehyde dehydrogenase family
A320_01178	COG2186	Transcriptional regulator
A320_01183	COG1960	acyl-CoA dehydrogenase activity
A320_01185	COG1012	belongs to the aldehyde dehydrogenase family
A320_01186	COG1024	Enoyl-CoA hydratase
A320_01187	COG2814	Major facilitator Superfamily
A320_01190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A320_01193	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A320_01203	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A320_01205	COG0583	DNA-binding transcription factor activity
A320_01206	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A320_01208	COG3316	Transposase and inactivated derivatives
A320_01212	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A320_01213	COG3316	Transposase and inactivated derivatives
A320_01218	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A320_01224	COG0308	aminopeptidase N
A320_01225	COG0512	Glutamine amidotransferase of anthranilate synthase
A320_01227	COG3104	oligopeptide transport
A320_01230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A320_01237	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A320_01238	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A320_01239	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A320_01243	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A320_01244	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A320_01245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A320_01248	COG1960	acyl-CoA dehydrogenase activity
A320_01249	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A320_01250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A320_01253	COG2223	nitrite transmembrane transporter activity
A320_01255	COG0024	Methionine aminopeptidase
A320_01256	COG0052	Belongs to the universal ribosomal protein uS2 family
A320_01259	COG2207	Transcriptional regulator
A320_01264	COG2951	lytic endotransglycosylase activity
A320_01265	COG0772	Belongs to the SEDS family
A320_01268	COG0842	Transport permease protein
A320_01269	COG1131	(ABC) transporter
A320_01276	COG1538	Outer membrane efflux protein
A320_01278	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A320_01282	COG4215	(ABC) transporter
A320_01283	COG4160	amino acid transport
A320_01284	COG4598	ABC transporter
A320_01286	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A320_01288	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A320_01291	COG1720	tRNA m6t6A37 methyltransferase activity
A320_01295	COG0745	RESPONSE REGULATOR receiver
A320_01296	COG0642	Histidine kinase
A320_01298	COG0494	nUDIX hydrolase
A320_01300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A320_01301	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A320_01302	COG3139	Protein of unknown function (DUF1315)
A320_01303	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A320_01304	COG1301	dicarboxylic acid transport
A320_01305	COG1960	acyl-CoA dehydrogenase activity
A320_01306	COG2819	hydrolase of the alpha beta superfamily
A320_01308	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A320_01310	COG2195	Cleaves the N-terminal amino acid of tripeptides
A320_01311	COG1234	tRNA 3'-trailer cleavage
A320_01317	COG2363	Small membrane protein
A320_01321	COG0513	Belongs to the DEAD box helicase family
A320_01323	COG0778	Nitroreductase
A320_01329	COG1286	toxin biosynthetic process
A320_01334	COG4783	chaperone-mediated protein folding
A320_01335	COG1610	YqeY-like protein
A320_01336	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A320_01355	COG3111	PFAM Bacterial OB fold (BOF) protein
A320_01360	COG3243	poly(R)-hydroxyalkanoic acid synthase
A320_01361	COG0786	glutamate:sodium symporter activity
A320_01363	COG2186	Transcriptional regulator
A320_01373	COG0477	Major facilitator Superfamily
A320_01377	COG2985	domain, Protein
A320_01379	COG2995	paraquat-inducible protein a
A320_01380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A320_01380	COG3008	intermembrane lipid transfer
A320_01382	COG1794	racemase activity, acting on amino acids and derivatives
A320_01388	COG1301	dicarboxylic acid transport
A320_01390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A320_01391	COG2011	ABC-type metal ion transport system permease component
A320_01392	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A320_01393	COG1464	Belongs to the NlpA lipoprotein family
A320_01394	COG0151	Belongs to the GarS family
A320_01395	COG0138	bifunctional purine biosynthesis protein purh
A320_01396	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
A320_01402	COG2308	Evidence 4 Homologs of previously reported genes of
A320_01404	COG1305	Transglutaminase-like
A320_01406	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A320_01407	COG0305	Participates in initiation and elongation during chromosome replication
A320_01412	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A320_01414	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A320_01415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A320_01420	COG1649	PFAM Uncharacterised BCR, COG1649
A320_01420	COG0726	polysaccharide deacetylase
A320_01421	COG1215	transferase activity, transferring glycosyl groups
A320_01422	COG3658	cytochrome
A320_01424	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A320_01427	COG0583	DNA-binding transcription factor activity
A320_01431	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A320_01432	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A320_01435	COG1960	acyl-CoA dehydrogenase activity
A320_01436	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A320_01437	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A320_01442	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A320_01443	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A320_01445	COG2205	protein histidine kinase activity
A320_01446	COG0745	RESPONSE REGULATOR receiver
A320_01447	COG0174	glutamine synthetase
A320_01451	COG0729	surface antigen
A320_01456	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A320_01457	COG2814	Major facilitator Superfamily
A320_01460	COG0583	DNA-binding transcription factor activity
A320_01463	COG1187	pseudouridine synthase activity
A320_01467	COG0802	atpase or kinase
A320_01468	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A320_01470	COG1923	regulation of RNA biosynthetic process
A320_01471	COG0697	spore germination
A320_01474	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A320_01477	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A320_01477	COG0519	Catalyzes the synthesis of GMP from XMP
A320_01478	COG4302	ethanolamine ammonia-lyase activity
A320_01479	COG4303	Ethanolamine ammonia lyase large subunit
A320_01480	COG0531	amino acid
A320_01484	COG1454	alcohol dehydrogenase
A320_01485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A320_01487	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A320_01491	COG0308	aminopeptidase N
A320_01493	COG4221	oxidoreductase activity
A320_01495	COG1605	Chorismate mutase
A320_01498	COG1309	transcriptional regulator
A320_01500	COG0668	transmembrane transport
A320_01506	COG4773	Receptor
A320_01510	COG0488	(ABC) transporter
A320_01511	COG0589	response to stress
A320_01516	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A320_01518	COG3135	benzoate transporter
A320_01519	COG1522	sequence-specific DNA binding
A320_01522	COG0583	DNA-binding transcription factor activity
A320_01524	COG0183	Belongs to the thiolase family
A320_01530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A320_01533	COG0824	Thioesterase
A320_01534	COG1454	alcohol dehydrogenase
A320_01536	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A320_01540	COG0069	glutamate synthase activity
A320_01544	COG2814	Major facilitator Superfamily
A320_01547	COG0511	ligase activity, forming carbon-carbon bonds
A320_01550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A320_01550	COG1116	anion transmembrane transporter activity
A320_01551	COG0745	RESPONSE REGULATOR receiver
A320_01553	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A320_01553	COG2146	nitrite reductase [NAD(P)H] activity
A320_01554	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A320_01555	COG0243	molybdopterin cofactor binding
A320_01557	COG0243	molybdopterin cofactor binding
A320_01558	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A320_01561	COG0521	Mo-molybdopterin cofactor biosynthetic process
A320_01561	COG0315	cyclic pyranopterin monophosphate synthase activity
A320_01562	COG0303	'Molybdopterin
A320_01564	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A320_01565	COG0697	spore germination
A320_01569	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A320_01570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A320_01581	COG2204	response regulator
A320_01582	COG3852	Histidine kinase
A320_01586	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A320_01587	COG0575	Belongs to the CDS family
A320_01594	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A320_01596	COG2137	regulation of response to DNA damage stimulus
A320_01598	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A320_01599	COG1011	Hydrolase
A320_01604	COG1522	sequence-specific DNA binding
A320_01606	COG1113	amino acid transport
A320_01609	COG0659	secondary active sulfate transmembrane transporter activity
A320_01610	COG2135	peptidase activity
A320_01613	COG3300	MHYT domain
A320_01613	COG5001	Diguanylate cyclase
A320_01618	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A320_01618	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A320_01618	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A320_01619	COG1105	Belongs to the carbohydrate kinase PfkB family
A320_01620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A320_01620	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A320_01626	COG0024	Methionine aminopeptidase
A320_01627	COG0583	DNA-binding transcription factor activity
A320_01629	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A320_01630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A320_01631	COG0517	IMP dehydrogenase activity
A320_01631	COG0516	GMP reductase activity
A320_01636	COG0552	protein localization to endoplasmic reticulum
A320_01638	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A320_01641	COG4890	Cyd operon protein YbgT
A320_01642	COG1294	oxidase, subunit
A320_01645	COG1585	Membrane protein implicated in regulation of membrane protease activity
A320_01647	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A320_01648	COG4774	siderophore transport
A320_01651	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A320_01652	COG0569	domain protein
A320_01653	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A320_01659	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A320_01660	COG0542	response to heat
A320_01662	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A320_01665	COG1902	pentaerythritol trinitrate reductase activity
A320_01665	COG0446	pyridine nucleotide-disulphide oxidoreductase
A320_01674	COG2323	membrane
A320_01675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A320_01677	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A320_01678	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A320_01679	COG0183	Belongs to the thiolase family
A320_01680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A320_01681	COG0596	Alpha beta hydrolase
A320_01682	COG2271	Major facilitator Superfamily
A320_01683	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A320_01684	COG3485	protocatechuate 3,4-dioxygenase
A320_01685	COG3485	protocatechuate 3,4-dioxygenase
A320_01686	COG0710	3-dehydroquinate dehydratase activity
A320_01687	COG3420	alginic acid biosynthetic process
A320_01688	COG3659	wide pore channel activity
A320_01689	COG4993	Dehydrogenase
A320_01691	COG2391	methyltransferase activity
A320_01694	COG1414	Transcriptional regulator
A320_01695	COG0583	DNA-binding transcription factor activity
A320_01696	COG1960	acyl-CoA dehydrogenase activity
A320_01701	COG2814	Major facilitator Superfamily
A320_01703	COG0154	amidase activity
A320_01707	COG4638	Rieske (2fe-2S)
A320_01709	COG1028	Short-chain dehydrogenase reductase Sdr
A320_01711	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A320_01713	COG3733	amine oxidase
A320_01715	COG1012	belongs to the aldehyde dehydrogenase family
A320_01717	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A320_01718	COG0183	Belongs to the thiolase family
A320_01719	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A320_01720	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A320_01722	COG4829	muconolactone delta-isomerase
A320_01723	COG4948	Mandelate Racemase Muconate Lactonizing
A320_01724	COG0583	DNA-binding transcription factor activity
A320_01726	COG2186	Transcriptional regulator
A320_01730	COG1012	belongs to the aldehyde dehydrogenase family
A320_01734	COG1960	acyl-CoA dehydrogenase activity
A320_01735	COG1028	Short-chain dehydrogenase reductase Sdr
A320_01736	COG3829	transcription factor binding
A320_01738	COG3162	membrane
A320_01741	COG1012	belongs to the aldehyde dehydrogenase family
A320_01744	COG0753	catalase activity
A320_01748	COG1846	Transcriptional regulator
A320_01749	COG0446	pyridine nucleotide-disulphide oxidoreductase
A320_01749	COG1902	pentaerythritol trinitrate reductase activity
A320_01751	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A320_01757	COG1309	transcriptional regulator
A320_01759	COG1335	isochorismatase
A320_01760	COG0583	DNA-binding transcription factor activity
A320_01762	COG0475	glutathione-regulated potassium exporter activity
A320_01762	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A320_01764	COG1473	amidohydrolase
A320_01766	COG2831	hemolysin activation secretion protein
A320_01767	COG3210	domain, Protein
A320_01776	COG0583	DNA-binding transcription factor activity
A320_01781	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A320_01782	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A320_01786	COG1566	PFAM secretion protein HlyD family protein
A320_01789	COG1012	belongs to the aldehyde dehydrogenase family
A320_01790	COG0129	dihydroxy-acid dehydratase activity
A320_01792	COG0583	DNA-binding transcription factor activity
A320_01793	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A320_01795	COG2084	Dehydrogenase
A320_01796	COG2207	Transcriptional regulator
A320_01799	COG1064	alcohol dehydrogenase
A320_01802	COG1120	ATPase activity
A320_01806	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A320_01830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A320_01841	COG1028	Short-chain dehydrogenase reductase Sdr
A320_01844	COG2207	Transcriptional regulator
A320_01846	COG2205	protein histidine kinase activity
A320_01847	COG0745	RESPONSE REGULATOR receiver
A320_01848	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A320_01849	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A320_01850	COG1538	Outer membrane efflux protein
A320_01852	COG2072	flavoprotein involved in K transport
A320_01856	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A320_01860	COG3539	Fimbrial protein
A320_01865	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A320_01867	COG0753	catalase activity
A320_01870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A320_01882	COG3433	isochorismatase activity
A320_01882	COG1535	isochorismatase
A320_01883	COG1028	Short-chain dehydrogenase reductase Sdr
A320_01884	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A320_01885	COG4149	molybdate abc transporter
A320_01886	COG0725	ABC transporter, periplasmic molybdate-binding protein
A320_01888	COG4638	Rieske (2fe-2S)
A320_01889	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A320_01890	COG0543	2 iron, 2 sulfur cluster binding
A320_01890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A320_01893	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A320_01895	COG1028	Short-chain dehydrogenase reductase Sdr
A320_01896	COG0412	Dienelactone hydrolase
A320_01898	COG2207	Transcriptional regulator
A320_01899	COG1028	Short-chain dehydrogenase reductase Sdr
A320_01900	COG2610	gluconate transmembrane transporter activity
A320_01902	COG0583	DNA-binding transcription factor activity
A320_01904	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A320_01905	COG2031	fatty acid transporter
A320_01906	COG0183	Belongs to the thiolase family
A320_01907	COG0583	DNA-binding transcription factor activity
A320_01908	COG0583	DNA-binding transcription factor activity
A320_01911	COG1027	Aspartate ammonia-lyase
A320_01913	COG0477	Major facilitator Superfamily
A320_01917	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A320_01918	COG4521	taurine ABC transporter
A320_01923	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A320_01924	COG1733	regulation of RNA biosynthetic process
A320_01925	COG3708	Transcriptional regulator
A320_01925	COG2207	Transcriptional regulator
A320_01928	COG0730	response to heat
A320_01930	COG3453	Protein conserved in bacteria
A320_01930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A320_01932	COG3781	membrane
A320_01933	COG1063	alcohol dehydrogenase
A320_01935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A320_01936	COG0508	dehydrogenase complex catalyzes the overall conversion of
A320_01937	COG0022	dehydrogenase e1 component
A320_01938	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A320_01939	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A320_01942	COG3706	GGDEF domain
A320_01945	COG0133	tryptophan synthase activity
A320_01947	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A320_01956	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A320_01961	COG2226	methyltransferase
A320_01972	COG0842	Transport permease protein
A320_01973	COG0842	Transport permease protein
A320_01974	COG1131	(ABC) transporter
A320_01977	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A320_01978	COG4773	Receptor
A320_01982	COG0730	response to heat
A320_01983	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A320_01987	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A320_01990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A320_01998	COG4264	IucA IucC family
A320_01999	COG4264	IucA IucC family
A320_02003	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A320_02006	COG1960	acyl-CoA dehydrogenase activity
A320_02007	COG1960	acyl-CoA dehydrogenase activity
A320_02008	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A320_02009	COG2207	Transcriptional regulator
A320_02010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A320_02011	COG0776	regulation of translation
A320_02016	COG0822	iron-sulfur transferase activity
A320_02017	COG0316	Belongs to the HesB IscA family
A320_02023	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A320_02027	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A320_02028	COG0702	epimerase
A320_02035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A320_02037	COG0339	signal peptide processing
A320_02047	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A320_02048	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A320_02054	COG0776	regulation of translation
A320_02058	COG0590	tRNA wobble adenosine to inosine editing
A320_02064	COG2165	general secretion pathway protein
A320_02067	COG0084	hydrolase, TatD family'
A320_02071	COG1663	tetraacyldisaccharide 4'-kinase activity
A320_02072	COG1132	(ABC) transporter
A320_02074	COG0811	peptide transport
A320_02075	COG1475	DNA binding
A320_02076	COG1192	Involved in chromosome partitioning
A320_02078	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A320_02081	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A320_02082	COG0191	fructose-bisphosphate aldolase activity
A320_02086	COG0424	maF-like protein
A320_02087	COG2850	peptidyl-arginine hydroxylation
A320_02089	COG0640	Transcriptional regulator
A320_02091	COG3619	membrane
A320_02092	COG3122	Protein conserved in bacteria
A320_02093	COG1132	(ABC) transporter
A320_02097	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A320_02098	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A320_02100	COG0506	proline dehydrogenase activity
A320_02100	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A320_02100	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A320_02101	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A320_02104	COG3698	Phosphodiester glycosidase
A320_02106	COG2353	YceI-like domain
A320_02108	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A320_02117	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A320_02117	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A320_02122	COG3539	Fimbrial protein
A320_02123	COG3121	Chaperone
A320_02128	COG0697	spore germination
A320_02130	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A320_02132	COG0583	DNA-binding transcription factor activity
A320_02137	COG1309	transcriptional regulator
A320_02140	COG1522	sequence-specific DNA binding
A320_02142	COG1126	abc transporter atp-binding protein
A320_02143	COG0765	amino acid transport
A320_02144	COG0765	amino acid transport
A320_02150	COG1464	Belongs to the NlpA lipoprotein family
A320_02152	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A320_02153	COG2011	ABC-type metal ion transport system permease component
A320_02154	COG0012	GTP binding
A320_02159	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A320_02167	COG0386	Belongs to the glutathione peroxidase family
A320_02169	COG0436	Aminotransferase
A320_02177	COG3634	alkyl hydroperoxide reductase activity
A320_02180	COG0583	DNA-binding transcription factor activity
A320_02181	COG0798	PFAM Bile acid sodium symporter
A320_02182	COG0640	Transcriptional regulator
A320_02185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A320_02187	COG0583	DNA-binding transcription factor activity
A320_02189	COG1953	Uracil, thiamine, allantoin
A320_02191	COG2175	clavaminate synthase activity
A320_02192	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A320_02193	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A320_02194	COG4521	taurine ABC transporter
A320_02196	COG0477	Major facilitator Superfamily
A320_02200	COG1271	oxidase subunit
A320_02201	COG1294	oxidase, subunit
A320_02203	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A320_02207	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A320_02211	COG3052	prosthetic group binding
A320_02212	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
A320_02214	COG2814	Major facilitator Superfamily
A320_02218	COG1346	cytolysis
A320_02220	COG0583	DNA-binding transcription factor activity
A320_02221	COG0625	glutathione transferase activity
A320_02222	COG0625	glutathione transferase activity
A320_02223	COG0583	DNA-binding transcription factor activity
A320_02226	COG1045	serine acetyltransferase
A320_02227	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A320_02228	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A320_02229	COG1280	lysine exporter protein (LysE YggA)
A320_02231	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A320_02232	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A320_02233	COG1126	abc transporter atp-binding protein
A320_02234	COG0765	amino acid transport
A320_02235	COG0765	amino acid transport
A320_02238	COG0784	Response regulator, receiver
A320_02238	COG2205	protein histidine kinase activity
A320_02242	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A320_02246	COG1028	Short-chain dehydrogenase reductase Sdr
A320_02257	COG0583	DNA-binding transcription factor activity
A320_02261	COG0318	PFAM AMP-dependent synthetase and ligase
A320_02262	COG1309	transcriptional regulator
A320_02263	COG1960	acyl-CoA dehydrogenase activity
A320_02264	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A320_02265	COG1024	Enoyl-CoA hydratase
A320_02268	COG0583	DNA-binding transcription factor activity
A320_02271	COG1960	acyl-CoA dehydrogenase activity
A320_02273	COG2814	Major facilitator Superfamily
A320_02275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A320_02276	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A320_02277	COG2814	Major facilitator Superfamily
A320_02278	COG1960	acyl-CoA dehydrogenase activity
A320_02279	COG1024	Enoyl-CoA hydratase
A320_02280	COG1028	Short-chain dehydrogenase reductase Sdr
A320_02281	COG1250	3-hydroxyacyl-CoA dehydrogenase
A320_02282	COG0183	Belongs to the thiolase family
A320_02284	COG2814	Major facilitator Superfamily
A320_02286	COG1024	Enoyl-CoA hydratase
A320_02289	COG1960	acyl-CoA dehydrogenase activity
A320_02290	COG2814	Major facilitator Superfamily
A320_02291	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A320_02292	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A320_02295	COG3842	ATPase activity
A320_02296	COG1840	ABC-type Fe3 transport system, periplasmic component
A320_02298	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A320_02299	COG1414	Transcriptional regulator
A320_02301	COG0583	DNA-binding transcription factor activity
A320_02302	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A320_02303	COG1012	belongs to the aldehyde dehydrogenase family
A320_02305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A320_02306	COG1012	belongs to the aldehyde dehydrogenase family
A320_02307	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A320_02308	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A320_02309	COG2267	carboxylic ester hydrolase activity
A320_02313	COG3038	cytochrome b561
A320_02314	COG0753	catalase activity
A320_02321	COG2050	protein possibly involved in aromatic compounds catabolism
A320_02323	COG3327	negative regulation of DNA-templated transcription, initiation
A320_02324	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A320_02325	COG0183	Belongs to the thiolase family
A320_02326	COG1250	3-hydroxyacyl-CoA dehydrogenase
A320_02327	COG1024	Enoyl-CoA hydratase
A320_02328	COG1024	Enoyl-CoA hydratase
A320_02329	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A320_02330	COG2151	metal-sulfur cluster biosynthetic enzyme
A320_02331	COG3396	Phenylacetate-CoA oxygenase
A320_02332	COG3460	Phenylacetate-CoA oxygenase
A320_02333	COG3396	Phenylacetate-CoA oxygenase
A320_02334	COG2030	dehydratase
A320_02334	COG1012	belongs to the aldehyde dehydrogenase family
A320_02335	COG1760	l-serine dehydratase
A320_02336	COG0531	amino acid
A320_02337	COG1012	belongs to the aldehyde dehydrogenase family
A320_02340	COG0446	pyridine nucleotide-disulphide oxidoreductase
A320_02342	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A320_02346	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A320_02349	COG0789	Transcriptional regulator
A320_02351	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A320_02354	COG2807	transmembrane transport
A320_02355	COG0590	tRNA wobble adenosine to inosine editing
A320_02357	COG0583	DNA-binding transcription factor activity
A320_02365	COG2885	chlorophyll binding
A320_02365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A320_02378	COG1116	anion transmembrane transporter activity
A320_02379	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A320_02381	COG0864	Transcriptional regulator
A320_02384	COG1733	regulation of RNA biosynthetic process
A320_02385	COG2249	NAD(P)H dehydrogenase (quinone) activity
A320_02386	COG0439	Biotin carboxylase
A320_02389	COG1063	alcohol dehydrogenase
A320_02391	COG1309	transcriptional regulator
A320_02396	COG0038	chloride channel
A320_02397	COG4770	biotin carboxylase activity
A320_02401	COG1914	H( )-stimulated, divalent metal cation uptake system
A320_02402	COG0583	DNA-binding transcription factor activity
A320_02405	COG3209	COG3209 Rhs family protein
A320_02406	COG3501	Rhs element vgr protein
A320_02411	COG1250	3-hydroxyacyl-CoA dehydrogenase
A320_02415	COG2814	Major facilitator Superfamily
A320_02417	COG1560	Kdo2-lipid A biosynthetic process
A320_02419	COG5006	permease, DMT superfamily
A320_02420	COG1522	sequence-specific DNA binding
A320_02423	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A320_02431	COG1538	Outer membrane efflux protein
A320_02432	COG1137	ATPase activity
A320_02433	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A320_02435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A320_02436	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A320_02436	COG0517	IMP dehydrogenase activity
A320_02443	COG1733	regulation of RNA biosynthetic process
A320_02444	COG2814	Major facilitator Superfamily
A320_02451	COG1278	Cold shock
A320_02452	COG1280	lysine exporter protein (LysE YggA)
A320_02459	COG1570	exodeoxyribonuclease VII activity
A320_02469	COG0583	DNA-binding transcription factor activity
A320_02470	COG4638	Rieske (2fe-2S)
A320_02471	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A320_02472	COG0633	Ferredoxin
A320_02472	COG0543	2 iron, 2 sulfur cluster binding
A320_02473	COG1028	Short-chain dehydrogenase reductase Sdr
A320_02474	COG3135	benzoate transporter
A320_02475	COG2814	Major facilitator Superfamily
A320_02478	COG1643	Atp-dependent helicase
A320_02479	COG0450	alkyl hydroperoxide reductase
A320_02481	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A320_02483	COG3634	alkyl hydroperoxide reductase activity
A320_02487	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A320_02488	COG0625	glutathione transferase activity
A320_02490	COG2885	chlorophyll binding
A320_02500	COG1765	OsmC-like protein
A320_02502	COG0667	Aldo Keto reductase
A320_02505	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A320_02507	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A320_02511	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A320_02513	COG3038	cytochrome b561
A320_02514	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A320_02515	COG2252	PERMEase
A320_02517	COG2072	flavoprotein involved in K transport
A320_02520	COG1741	Belongs to the pirin family
A320_02521	COG1309	transcriptional regulator
A320_02523	COG0300	oxidoreductase activity
A320_02524	COG2072	flavoprotein involved in K transport
A320_02525	COG3316	Transposase and inactivated derivatives
A320_02536	COG3316	Transposase and inactivated derivatives
A320_02543	COG3316	Transposase and inactivated derivatives
A320_02546	COG3677	Transposase
A320_02548	COG3316	Transposase and inactivated derivatives
A320_02550	COG3316	Transposase and inactivated derivatives
A320_02553	COG3739	integral membrane protein
A320_02556	COG1169	isochorismate synthase
A320_02558	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A320_02560	COG1132	(ABC) transporter
A320_02563	COG3433	isochorismatase activity
A320_02563	COG1535	isochorismatase
A320_02564	COG1021	2,3-dihydroxybenzoate-AMP ligase
A320_02565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A320_02567	COG4774	siderophore transport
A320_02568	COG4607	ABC-type enterochelin transport system periplasmic component
A320_02569	COG4604	ABC transporter, ATP-binding protein
A320_02570	COG4605	iron ion homeostasis
A320_02571	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A320_02574	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A320_02577	COG2964	Protein conserved in bacteria
A320_02580	COG1741	Belongs to the pirin family
A320_02583	COG1309	transcriptional regulator
A320_02585	COG4948	Mandelate Racemase Muconate Lactonizing
A320_02586	COG2814	Major facilitator Superfamily
A320_02593	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A320_02593	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A320_02594	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A320_02597	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A320_02598	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A320_02599	COG0583	DNA-binding transcription factor activity
A320_02600	COG1113	amino acid transport
A320_02604	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A320_02604	COG2508	Transcriptional regulator
A320_02611	COG2879	small protein
A320_02612	COG1966	Carbon starvation protein
A320_02621	COG1067	ATP-dependent peptidase activity
A320_02622	COG0583	DNA-binding transcription factor activity
A320_02627	COG1686	Belongs to the peptidase S11 family
A320_02628	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A320_02635	COG0616	signal peptide processing
A320_02636	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A320_02638	COG0573	inorganic phosphate transmembrane transporter activity
A320_02639	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A320_02640	COG1113	amino acid transport
A320_02641	COG3961	Belongs to the TPP enzyme family
A320_02642	COG1522	sequence-specific DNA binding
A320_02644	COG0076	glutamate decarboxylase activity
A320_02645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A320_02647	COG1309	transcriptional regulator
A320_02650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A320_02657	COG0352	thiamine-phosphate diphosphorylase activity
A320_02662	COG0612	Peptidase, M16
A320_02665	COG0583	DNA-binding transcription factor activity
A320_02666	COG0477	Major facilitator Superfamily
A320_02670	COG1187	pseudouridine synthase activity
A320_02673	COG1686	Belongs to the peptidase S11 family
A320_02674	COG1252	NADH dehydrogenase
A320_02676	COG0415	Belongs to the DNA photolyase family
A320_02679	COG1215	transferase activity, transferring glycosyl groups
A320_02685	COG2070	2-Nitropropane dioxygenase
A320_02724	COG5410	chromosome segregation
A320_02765	COG0556	nucleotide-excision repair
A320_02774	COG4221	oxidoreductase activity
A320_02776	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A320_02777	COG1381	Involved in DNA repair and RecF pathway recombination
A320_02779	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A320_02782	COG0681	Belongs to the peptidase S26 family
A320_02785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A320_02789	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A320_02790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A320_02791	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A320_02793	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A320_02794	COG4208	sulfate ABC transporter
A320_02795	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A320_02796	COG0583	DNA-binding transcription factor activity
A320_02797	COG4625	pathogenesis
A320_02800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A320_02803	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A320_02805	COG1056	cytidyltransferase-related domain
A320_02805	COG1051	belongs to the nudix hydrolase family
A320_02806	COG1024	Enoyl-CoA hydratase
A320_02807	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A320_02809	COG2814	Major facilitator Superfamily
A320_02810	COG0047	phosphoribosylformylglycinamidine synthase activity
A320_02810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A320_02814	COG1473	amidohydrolase
A320_02815	COG0824	Thioesterase
A320_02819	COG0823	Involved in the tonB-independent uptake of proteins
A320_02823	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A320_02830	COG0628	permease
A320_02832	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A320_02833	COG0596	Alpha beta hydrolase
A320_02834	COG0616	signal peptide processing
A320_02834	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A320_02836	COG2333	competence protein COMEC
A320_02836	COG0658	competence protein
A320_02837	COG1136	(ABC) transporter
A320_02838	COG4591	ABC-type transport system involved in lipoprotein release permease component
A320_02845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A320_02849	COG0463	Glycosyl transferase, family 2
A320_02855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A320_02856	COG1280	lysine exporter protein (LysE YggA)
A320_02858	COG0019	diaminopimelate decarboxylase activity
A320_02860	COG1113	amino acid transport
A320_02863	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
A320_02865	COG3339	Conserved Protein
A320_02866	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A320_02867	COG0243	molybdopterin cofactor binding
A320_02868	COG1929	Belongs to the glycerate kinase type-1 family
A320_02871	COG0778	Nitroreductase
A320_02876	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A320_02879	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A320_02883	COG0741	lytic transglycosylase activity
A320_02887	COG0584	glycerophosphoryl diester phosphodiesterase
A320_02888	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A320_02893	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A320_02897	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A320_02898	COG0477	Major facilitator Superfamily
A320_02908	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A320_02909	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A320_02914	COG0505	Belongs to the CarA family
A320_02918	COG0589	response to stress
A320_02921	COG2843	Capsule synthesis protein
A320_02925	COG2321	neutral zinc metallopeptidase
A320_02926	COG2354	Protein conserved in bacteria
A320_02930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A320_02933	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A320_02934	COG1053	succinate dehydrogenase
A320_02935	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A320_02936	COG2009	succinate dehydrogenase
A320_02944	COG2921	Belongs to the UPF0250 family
A320_02945	COG0321	lipoyl(octanoyl) transferase activity
A320_02948	COG0531	amino acid
A320_02950	COG1733	regulation of RNA biosynthetic process
A320_02951	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A320_02952	COG1648	precorrin-2 dehydrogenase activity
A320_02952	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A320_02955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A320_02960	COG0671	phosphoesterase, PA-phosphatase related
A320_02961	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A320_02963	COG1538	Outer membrane efflux protein
A320_02964	COG0393	Putative heavy-metal-binding
A320_02965	COG0393	Putative heavy-metal-binding
A320_02967	COG1028	Short-chain dehydrogenase reductase Sdr
A320_02969	COG0525	valine-tRNA ligase activity
A320_02973	COG0583	DNA-binding transcription factor activity
A320_02974	COG0004	ammonium transporteR
A320_02976	COG0642	Histidine kinase
A320_02977	COG0745	RESPONSE REGULATOR receiver
A320_02978	COG2194	sulfuric ester hydrolase activity
A320_02982	COG1752	Esterase of the alpha-beta hydrolase superfamily
A320_02985	COG2315	Protein conserved in bacteria
A320_02986	COG0142	geranyltranstransferase activity
A320_02987	COG2828	Protein conserved in bacteria
A320_02988	COG1113	amino acid transport
A320_02992	COG2207	Transcriptional regulator
A320_02997	COG2249	NAD(P)H dehydrogenase (quinone) activity
A320_03001	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A320_03003	COG1530	ribonuclease E activity
A320_03004	COG0424	maF-like protein
A320_03005	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A320_03006	COG1792	Involved in formation and maintenance of cell shape
A320_03007	COG1077	Cell shape determining protein MreB Mrl
A320_03008	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A320_03010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A320_03016	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A320_03017	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A320_03018	COG1752	Esterase of the alpha-beta hydrolase superfamily
A320_03019	COG1115	amino acid carrier protein
A320_03022	COG2814	Major facilitator Superfamily
A320_03023	COG1289	transmembrane transporter activity
A320_03033	COG1376	ErfK ybiS ycfS ynhG family protein
A320_03034	COG2832	Protein of unknown function (DUF454)
A320_03036	COG5510	response to toxic substance
A320_03040	COG0840	transmembrane signaling receptor activity
A320_03048	COG3422	double-strand break repair
A320_03049	COG2824	Alkylphosphonate utilization operon protein PhnA
A320_03050	COG3189	MarR family transcriptional regulator
A320_03052	COG0354	folic acid binding
A320_03053	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A320_03055	COG0679	Auxin Efflux Carrier
A320_03056	COG1902	pentaerythritol trinitrate reductase activity
A320_03057	COG4772	TonB-dependent receptor
A320_03058	COG2094	Belongs to the DNA glycosylase MPG family
A320_03064	COG2233	PERMEase
A320_03066	COG0833	amino acid
A320_03067	COG1690	Belongs to the RtcB family
A320_03069	COG2885	chlorophyll binding
A320_03069	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A320_03071	COG0183	Belongs to the thiolase family
A320_03075	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A320_03079	COG2207	Transcriptional regulator
A320_03080	COG0183	Belongs to the thiolase family
A320_03087	COG1272	protein, Hemolysin III
A320_03088	COG0477	Major facilitator Superfamily
A320_03091	COG0450	alkyl hydroperoxide reductase
A320_03095	COG0285	dihydrofolate synthase activity
A320_03102	COG0133	tryptophan synthase activity
A320_03105	COG2096	Adenosyltransferase
A320_03109	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A320_03110	COG0745	RESPONSE REGULATOR receiver
A320_03111	COG2205	protein histidine kinase activity
A320_03113	COG1960	acyl-CoA dehydrogenase activity
A320_03114	COG1960	acyl-CoA dehydrogenase activity
A320_03115	COG0583	DNA-binding transcription factor activity
A320_03116	COG0625	glutathione transferase activity
A320_03129	COG0438	transferase activity, transferring glycosyl groups
A320_03130	COG0463	Glycosyl transferase, family 2
A320_03131	COG0726	polysaccharide deacetylase
A320_03135	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A320_03136	COG2205	protein histidine kinase activity
A320_03145	COG1862	Preprotein translocase
A320_03147	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A320_03148	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A320_03150	COG3781	membrane
A320_03151	COG0613	PHP domain protein
A320_03153	COG2350	Protein conserved in bacteria
A320_03159	COG1607	acyl-coa hydrolase
A320_03162	COG3453	Protein conserved in bacteria
A320_03162	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A320_03171	COG2199	diguanylate cyclase activity
A320_03173	COG1408	metallophosphoesterase
A320_03174	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A320_03176	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A320_03180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A320_03181	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A320_03184	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A320_03186	COG2969	positive regulation of protein catabolic process
A320_03190	COG1960	acyl-CoA dehydrogenase activity
A320_03191	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A320_03194	COG1309	transcriptional regulator
A320_03195	COG1960	acyl-CoA dehydrogenase activity
A320_03204	COG1183	phosphatidylcholine synthase activity
A320_03205	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A320_03211	COG1196	nuclear chromosome segregation
A320_03211	COG0739	heme binding
A320_03211	COG0741	lytic transglycosylase activity
A320_03213	COG1702	phosphate starvation-inducible protein PhoH
A320_03220	COG1295	ribonuclease BN
A320_03221	COG0697	spore germination
A320_03222	COG2169	Transcriptional regulator
A320_03223	COG0179	Fumarylacetoacetate (FAA) hydrolase
A320_03232	COG0557	exoribonuclease II activity
A320_03233	COG0339	signal peptide processing
A320_03234	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A320_03241	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A320_03242	COG1960	acyl-CoA dehydrogenase activity
A320_03247	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A320_03249	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A320_03273	COG0626	cystathionine gamma-synthase activity
A320_03274	COG0433	COG0433 Predicted ATPase
A320_03275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A320_03275	COG1017	nitric oxide dioxygenase activity
A320_03276	COG1959	2 iron, 2 sulfur cluster binding
A320_03279	COG1301	dicarboxylic acid transport
A320_03280	COG1946	Acyl-CoA thioesterase
A320_03284	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A320_03285	COG1040	competence protein
A320_03286	COG0494	nUDIX hydrolase
A320_03288	COG0598	Magnesium transport protein CorA
A320_03290	COG2854	intermembrane phospholipid transfer
A320_03292	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A320_03293	COG1127	ABC transporter
A320_03294	COG0513	Belongs to the DEAD box helicase family
A320_03298	COG0408	coproporphyrinogen oxidase activity
A320_03301	COG1960	acyl-CoA dehydrogenase activity
A320_03303	COG1983	PspC domain protein
A320_03304	COG0517	IMP dehydrogenase activity
A320_03313	COG0583	DNA-binding transcription factor activity
A320_03321	COG1012	belongs to the aldehyde dehydrogenase family
A320_03323	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A320_03324	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A320_03325	COG0833	amino acid
A320_03332	COG0628	permease
A320_03334	COG1289	transmembrane transporter activity
A320_03337	COG2249	NAD(P)H dehydrogenase (quinone) activity
A320_03338	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A320_03340	COG0277	FAD linked oxidase domain protein
A320_03341	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A320_03346	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A320_03347	COG5380	lipid catabolic process
A320_03351	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A320_03361	COG0194	GDP metabolic process
A320_03363	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A320_03367	COG3307	-O-antigen
A320_03371	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A320_03372	COG1704	LemA family
A320_03374	COG0493	'glutamate synthase
A320_03375	COG0067	glutamate synthase
A320_03375	COG0069	glutamate synthase activity
A320_03375	COG0070	glutamate synthase
A320_03385	COG2226	methyltransferase
A320_03388	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A320_03389	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A320_03398	COG0833	amino acid
A320_03411	COG0488	(ABC) transporter
A320_03413	COG4221	oxidoreductase activity
A320_03414	COG0659	secondary active sulfate transmembrane transporter activity
A320_03416	COG0745	RESPONSE REGULATOR receiver
A320_03418	COG0427	acetyl-CoA hydrolase
A320_03424	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A320_03432	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A320_03443	COG2207	Transcriptional regulator
A320_03444	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A320_03447	COG2249	NAD(P)H dehydrogenase (quinone) activity
A320_03448	COG1733	regulation of RNA biosynthetic process
A320_03452	COG1733	regulation of RNA biosynthetic process
A320_03456	COG0667	Aldo Keto reductase
A320_03461	COG0583	DNA-binding transcription factor activity
A320_03462	COG2814	Major facilitator Superfamily
A320_03469	COG1335	isochorismatase
A320_03471	COG1012	belongs to the aldehyde dehydrogenase family
A320_03472	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A320_03474	COG1113	amino acid transport
A320_03476	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A320_03479	COG2814	Major facilitator Superfamily
A320_03481	COG0352	thiamine-phosphate diphosphorylase activity
A320_03481	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A320_03481	COG0351	phosphomethylpyrimidine kinase
A320_03485	COG1309	transcriptional regulator
A320_03486	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A320_03487	COG3706	GGDEF domain
A320_03489	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A320_03491	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A320_03492	COG3162	membrane
A320_03493	COG2205	protein histidine kinase activity
A320_03493	COG2198	Histidine kinase
A320_03493	COG0784	Response regulator, receiver
A320_03498	COG1522	sequence-specific DNA binding
A320_03499	COG1335	isochorismatase
A320_03500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A320_03502	COG0668	transmembrane transport
A320_03503	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A320_03504	COG1519	Transferase
A320_03505	COG1902	pentaerythritol trinitrate reductase activity
A320_03510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A320_03515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A320_03515	COG0426	domain, Protein
A320_03516	COG4774	siderophore transport
A320_03517	COG2119	membrane
A320_03519	COG0508	dehydrogenase complex catalyzes the overall conversion of
A320_03521	COG4942	peptidase
A320_03524	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A320_03526	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A320_03530	COG0189	ligase activity
A320_03534	COG0708	Exodeoxyribonuclease III
A320_03535	COG1393	Belongs to the ArsC family
A320_03539	COG3706	GGDEF domain
A320_03547	COG2233	PERMEase
A320_03549	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A320_03551	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
A320_03553	COG3150	esterase
A320_03558	COG3179	chitinase
A320_03559	COG3501	Rhs element vgr protein
A320_03561	COG2918	glutathione biosynthetic process
A320_03564	COG2733	membrane
A320_03565	COG0436	Aminotransferase
A320_03566	COG0534	Mate efflux family protein
A320_03578	COG0753	catalase activity
A320_03587	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A320_03588	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A320_03590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A320_03591	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A320_03592	COG0546	phosphoglycolate phosphatase activity
A320_03594	COG0010	Belongs to the arginase family
A320_03600	COG2188	Transcriptional regulator
A320_03602	COG0523	cobalamin synthesis protein
A320_03604	COG1113	amino acid transport
A320_03606	COG0625	glutathione transferase activity
A320_03610	COG1683	Conserved Protein
A320_03611	COG0534	Mate efflux family protein
A320_03612	COG0385	Bile acid
A320_03613	COG1335	isochorismatase
A320_03614	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A320_03618	COG2116	formate transmembrane transporter activity
A320_03619	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A320_03620	COG2133	pyrroloquinoline quinone binding
A320_03621	COG2983	Belongs to the UPF0260 family
A320_03625	COG1194	a g-specific adenine glycosylase
A320_03628	COG2818	Glycosylase
A320_03629	COG1064	alcohol dehydrogenase
A320_03630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A320_03632	COG0583	DNA-binding transcription factor activity
A320_03633	COG0656	L-ascorbic acid biosynthetic process
A320_03634	COG2814	Major facilitator Superfamily
A320_03641	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A320_03644	COG2233	PERMEase
A320_03652	COG0733	neurotransmitter:sodium symporter activity
A320_03662	COG3316	Transposase and inactivated derivatives