locus-tag	class	description
NIY06_00010	COG0592	DNA-directed DNA polymerase activity
NIY06_00020	COG0187	DNA topoisomerase II activity
NIY06_00030	COG0586	Pfam SNARE associated Golgi protein
NIY06_00035	COG0488	(ABC) transporter
NIY06_00060	COG0596	Alpha beta hydrolase
NIY06_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NIY06_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIY06_00110	COG0733	neurotransmitter:sodium symporter activity
NIY06_00150	COG2233	PERMEase
NIY06_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY06_00200	COG2814	Major facilitator Superfamily
NIY06_00205	COG0656	L-ascorbic acid biosynthetic process
NIY06_00210	COG0583	DNA-binding transcription factor activity
NIY06_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY06_00230	COG1064	alcohol dehydrogenase
NIY06_00235	COG2818	Glycosylase
NIY06_00250	COG1194	a g-specific adenine glycosylase
NIY06_00270	COG2983	Belongs to the UPF0260 family
NIY06_00275	COG2133	pyrroloquinoline quinone binding
NIY06_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NIY06_00285	COG2116	formate transmembrane transporter activity
NIY06_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY06_00310	COG1335	isochorismatase
NIY06_00315	COG0385	Bile acid
NIY06_00320	COG0534	Mate efflux family protein
NIY06_00325	COG1683	Conserved Protein
NIY06_00345	COG0625	glutathione transferase activity
NIY06_00355	COG1113	amino acid transport
NIY06_00365	COG0523	cobalamin synthesis protein
NIY06_00375	COG2188	Transcriptional regulator
NIY06_00405	COG0010	Belongs to the arginase family
NIY06_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NIY06_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NIY06_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NIY06_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NIY06_00540	COG0534	Mate efflux family protein
NIY06_00545	COG0436	Aminotransferase
NIY06_00550	COG2733	membrane
NIY06_00565	COG2918	glutathione biosynthetic process
NIY06_00580	COG1388	LysM domain
NIY06_00580	COG0791	NLP P60 protein
NIY06_00595	COG3150	esterase
NIY06_00605	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NIY06_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY06_00630	COG2233	PERMEase
NIY06_00635	COG2351	hydroxyisourate hydrolase activity
NIY06_00670	COG3706	GGDEF domain
NIY06_00685	COG1393	Belongs to the ArsC family
NIY06_00690	COG0708	Exodeoxyribonuclease III
NIY06_00710	COG0189	ligase activity
NIY06_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NIY06_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIY06_00755	COG4942	peptidase
NIY06_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
NIY06_00775	COG2119	membrane
NIY06_00780	COG4774	siderophore transport
NIY06_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY06_00785	COG0426	domain, Protein
NIY06_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NIY06_00830	COG1902	pentaerythritol trinitrate reductase activity
NIY06_00835	COG1519	Transferase
NIY06_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NIY06_00845	COG0668	transmembrane transport
NIY06_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY06_00860	COG1335	isochorismatase
NIY06_00865	COG1522	sequence-specific DNA binding
NIY06_00870	COG3328	transposase activity
NIY06_00900	COG2198	Histidine kinase
NIY06_00900	COG2205	protein histidine kinase activity
NIY06_00900	COG0784	Response regulator, receiver
NIY06_00905	COG3162	membrane
NIY06_00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIY06_00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY06_00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIY06_00945	COG1309	transcriptional regulator
NIY06_00965	COG0351	phosphomethylpyrimidine kinase
NIY06_00965	COG0352	thiamine-phosphate diphosphorylase activity
NIY06_00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIY06_00975	COG2814	Major facilitator Superfamily
NIY06_00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NIY06_01000	COG1113	amino acid transport
NIY06_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIY06_01015	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_01025	COG1335	isochorismatase
NIY06_01055	COG2814	Major facilitator Superfamily
NIY06_01060	COG0583	DNA-binding transcription factor activity
NIY06_01080	COG0667	Aldo Keto reductase
NIY06_01115	COG1733	regulation of RNA biosynthetic process
NIY06_01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY06_01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NIY06_01200	COG2329	Antibiotic biosynthesis monooxygenase
NIY06_01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIY06_01260	COG0427	acetyl-CoA hydrolase
NIY06_01285	COG0659	secondary active sulfate transmembrane transporter activity
NIY06_01290	COG4221	oxidoreductase activity
NIY06_01295	COG2873	o-acetylhomoserine
NIY06_01300	COG0488	(ABC) transporter
NIY06_01385	COG0833	amino acid
NIY06_01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIY06_01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NIY06_01450	COG2226	methyltransferase
NIY06_01500	COG0069	glutamate synthase activity
NIY06_01500	COG0067	glutamate synthase
NIY06_01500	COG0070	glutamate synthase
NIY06_01505	COG0493	'glutamate synthase
NIY06_01515	COG1704	LemA family
NIY06_01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NIY06_01540	COG3307	-O-antigen
NIY06_01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIY06_01580	COG0194	GDP metabolic process
NIY06_01630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIY06_01650	COG5380	lipid catabolic process
NIY06_01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIY06_01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NIY06_01685	COG0277	FAD linked oxidase domain protein
NIY06_01695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NIY06_01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY06_01715	COG1289	transmembrane transporter activity
NIY06_01725	COG0628	permease
NIY06_01730	COG1192	Involved in chromosome partitioning
NIY06_01760	COG0833	amino acid
NIY06_01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NIY06_01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NIY06_01780	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_01820	COG0583	DNA-binding transcription factor activity
NIY06_01865	COG0517	IMP dehydrogenase activity
NIY06_01870	COG1983	PspC domain protein
NIY06_01880	COG1960	acyl-CoA dehydrogenase activity
NIY06_01895	COG0408	coproporphyrinogen oxidase activity
NIY06_01915	COG0513	Belongs to the DEAD box helicase family
NIY06_01925	COG1127	ABC transporter
NIY06_01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NIY06_01940	COG2854	intermembrane phospholipid transfer
NIY06_01950	COG0598	Magnesium transport protein CorA
NIY06_01960	COG0494	nUDIX hydrolase
NIY06_01965	COG1040	competence protein
NIY06_01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIY06_01990	COG1946	Acyl-CoA thioesterase
NIY06_01995	COG1301	dicarboxylic acid transport
NIY06_02010	COG1959	2 iron, 2 sulfur cluster binding
NIY06_02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY06_02015	COG1017	nitric oxide dioxygenase activity
NIY06_02020	COG0433	COG0433 Predicted ATPase
NIY06_02025	COG0626	cystathionine gamma-synthase activity
NIY06_02180	COG1960	acyl-CoA dehydrogenase activity
NIY06_02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NIY06_02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NIY06_02220	COG0339	signal peptide processing
NIY06_02225	COG0557	exoribonuclease II activity
NIY06_02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
NIY06_02275	COG2169	Transcriptional regulator
NIY06_02280	COG0697	spore germination
NIY06_02285	COG1295	ribonuclease BN
NIY06_02320	COG1702	phosphate starvation-inducible protein PhoH
NIY06_02330	COG0739	heme binding
NIY06_02330	COG0741	lytic transglycosylase activity
NIY06_02330	COG1196	nuclear chromosome segregation
NIY06_02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NIY06_02365	COG1183	phosphatidylcholine synthase activity
NIY06_02410	COG1960	acyl-CoA dehydrogenase activity
NIY06_02415	COG1309	transcriptional regulator
NIY06_02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NIY06_02435	COG1960	acyl-CoA dehydrogenase activity
NIY06_02455	COG2969	positive regulation of protein catabolic process
NIY06_02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NIY06_02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NIY06_02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NIY06_02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIY06_02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIY06_02520	COG1408	metallophosphoesterase
NIY06_02530	COG2199	diguanylate cyclase activity
NIY06_02590	COG1607	acyl-coa hydrolase
NIY06_02620	COG2350	Protein conserved in bacteria
NIY06_02630	COG0613	PHP domain protein
NIY06_02635	COG3781	membrane
NIY06_02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIY06_02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NIY06_02660	COG1862	Preprotein translocase
NIY06_02690	COG2205	protein histidine kinase activity
NIY06_02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NIY06_02715	COG0726	polysaccharide deacetylase
NIY06_02720	COG0463	Glycosyl transferase, family 2
NIY06_02725	COG0438	transferase activity, transferring glycosyl groups
NIY06_02790	COG0625	glutathione transferase activity
NIY06_02795	COG0583	DNA-binding transcription factor activity
NIY06_02800	COG1960	acyl-CoA dehydrogenase activity
NIY06_02805	COG1960	acyl-CoA dehydrogenase activity
NIY06_02815	COG2205	protein histidine kinase activity
NIY06_02820	COG0745	RESPONSE REGULATOR receiver
NIY06_02825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NIY06_02845	COG2096	Adenosyltransferase
NIY06_02895	COG0285	dihydrofolate synthase activity
NIY06_02915	COG0450	alkyl hydroperoxide reductase
NIY06_02930	COG0477	Major facilitator Superfamily
NIY06_02935	COG1272	protein, Hemolysin III
NIY06_02965	COG0183	Belongs to the thiolase family
NIY06_02970	COG2207	Transcriptional regulator
NIY06_02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY06_03010	COG0183	Belongs to the thiolase family
NIY06_03020	COG2885	chlorophyll binding
NIY06_03020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NIY06_03030	COG1690	Belongs to the RtcB family
NIY06_03035	COG0833	amino acid
NIY06_03045	COG2233	PERMEase
NIY06_03050	COG1217	gtp-binding protein TYPA
NIY06_03075	COG2094	Belongs to the DNA glycosylase MPG family
NIY06_03095	COG1902	pentaerythritol trinitrate reductase activity
NIY06_03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY06_03115	COG0354	folic acid binding
NIY06_03125	COG3189	MarR family transcriptional regulator
NIY06_03130	COG2824	Alkylphosphonate utilization operon protein PhnA
NIY06_03135	COG3422	double-strand break repair
NIY06_03175	COG0840	transmembrane signaling receptor activity
NIY06_03195	COG5510	response to toxic substance
NIY06_03205	COG2832	Protein of unknown function (DUF454)
NIY06_03210	COG1376	ErfK ybiS ycfS ynhG family protein
NIY06_03250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NIY06_03260	COG1289	transmembrane transporter activity
NIY06_03265	COG2814	Major facilitator Superfamily
NIY06_03285	COG1115	amino acid carrier protein
NIY06_03290	COG1752	Esterase of the alpha-beta hydrolase superfamily
NIY06_03295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIY06_03300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NIY06_03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIY06_03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIY06_03345	COG1077	Cell shape determining protein MreB Mrl
NIY06_03350	COG1792	Involved in formation and maintenance of cell shape
NIY06_03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NIY06_03360	COG0424	maF-like protein
NIY06_03365	COG1530	ribonuclease E activity
NIY06_03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY06_03385	COG0560	Phosphoserine phosphatase
NIY06_03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY06_03420	COG2207	Transcriptional regulator
NIY06_03440	COG1113	amino acid transport
NIY06_03445	COG2828	Protein conserved in bacteria
NIY06_03450	COG0142	geranyltranstransferase activity
NIY06_03455	COG2315	Protein conserved in bacteria
NIY06_03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
NIY06_03490	COG2194	sulfuric ester hydrolase activity
NIY06_03495	COG0745	RESPONSE REGULATOR receiver
NIY06_03500	COG0642	Histidine kinase
NIY06_03510	COG0004	ammonium transporteR
NIY06_03515	COG0583	DNA-binding transcription factor activity
NIY06_03535	COG0525	valine-tRNA ligase activity
NIY06_03545	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_03555	COG0393	Putative heavy-metal-binding
NIY06_03560	COG0393	Putative heavy-metal-binding
NIY06_03565	COG1538	Outer membrane efflux protein
NIY06_03575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY06_03580	COG0671	phosphoesterase, PA-phosphatase related
NIY06_03610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NIY06_03625	COG1648	precorrin-2 dehydrogenase activity
NIY06_03625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NIY06_03630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NIY06_03635	COG1733	regulation of RNA biosynthetic process
NIY06_03645	COG0531	amino acid
NIY06_03660	COG0321	lipoyl(octanoyl) transferase activity
NIY06_03665	COG2921	Belongs to the UPF0250 family
NIY06_03705	COG2009	succinate dehydrogenase
NIY06_03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NIY06_03715	COG1053	succinate dehydrogenase
NIY06_03720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NIY06_03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY06_03765	COG2354	Protein conserved in bacteria
NIY06_03770	COG2321	neutral zinc metallopeptidase
NIY06_03790	COG2843	Capsule synthesis protein
NIY06_03805	COG0589	response to stress
NIY06_03825	COG0505	Belongs to the CarA family
NIY06_03850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIY06_03855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NIY06_03905	COG0477	Major facilitator Superfamily
NIY06_03910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIY06_03925	COG1597	lipid kinase activity
NIY06_03930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIY06_03960	COG0584	glycerophosphoryl diester phosphodiesterase
NIY06_03980	COG0741	lytic transglycosylase activity
NIY06_04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NIY06_04015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY06_04045	COG0778	Nitroreductase
NIY06_04060	COG1929	Belongs to the glycerate kinase type-1 family
NIY06_04065	COG0243	molybdopterin cofactor binding
NIY06_04070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NIY06_04075	COG3339	Conserved Protein
NIY06_04085	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NIY06_04100	COG1113	amino acid transport
NIY06_04110	COG0019	diaminopimelate decarboxylase activity
NIY06_04120	COG1280	lysine exporter protein (LysE YggA)
NIY06_04125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NIY06_04155	COG0463	Glycosyl transferase, family 2
NIY06_04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY06_04210	COG4591	ABC-type transport system involved in lipoprotein release permease component
NIY06_04215	COG1136	(ABC) transporter
NIY06_04220	COG0658	competence protein
NIY06_04220	COG2333	competence protein COMEC
NIY06_04230	COG0616	signal peptide processing
NIY06_04230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NIY06_04235	COG0596	Alpha beta hydrolase
NIY06_04240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIY06_04250	COG0628	permease
NIY06_04285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIY06_04305	COG0823	Involved in the tonB-independent uptake of proteins
NIY06_04325	COG0824	Thioesterase
NIY06_04330	COG1473	amidohydrolase
NIY06_04350	COG0047	phosphoribosylformylglycinamidine synthase activity
NIY06_04350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIY06_04355	COG2814	Major facilitator Superfamily
NIY06_04370	COG1024	Enoyl-CoA hydratase
NIY06_04375	COG1051	belongs to the nudix hydrolase family
NIY06_04375	COG1056	cytidyltransferase-related domain
NIY06_04385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NIY06_04400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NIY06_04415	COG4625	pathogenesis
NIY06_04420	COG0583	DNA-binding transcription factor activity
NIY06_04425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NIY06_04430	COG4208	sulfate ABC transporter
NIY06_04435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NIY06_04445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NIY06_04450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NIY06_04455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIY06_04475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIY06_04490	COG0681	Belongs to the peptidase S26 family
NIY06_04505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIY06_04515	COG1381	Involved in DNA repair and RecF pathway recombination
NIY06_04520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NIY06_04530	COG4221	oxidoreductase activity
NIY06_04560	COG0436	Aminotransferase
NIY06_04580	COG0556	nucleotide-excision repair
NIY06_04635	COG2070	2-Nitropropane dioxygenase
NIY06_04665	COG1215	transferase activity, transferring glycosyl groups
NIY06_04680	COG0415	Belongs to the DNA photolyase family
NIY06_04690	COG1252	NADH dehydrogenase
NIY06_04695	COG1686	Belongs to the peptidase S11 family
NIY06_04710	COG1187	pseudouridine synthase activity
NIY06_04735	COG0477	Major facilitator Superfamily
NIY06_04740	COG0583	DNA-binding transcription factor activity
NIY06_04745	COG1823	symporter activity
NIY06_04755	COG0612	Peptidase, M16
NIY06_04780	COG0352	thiamine-phosphate diphosphorylase activity
NIY06_04815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY06_04830	COG1309	transcriptional regulator
NIY06_04840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIY06_04845	COG0076	glutamate decarboxylase activity
NIY06_04855	COG1522	sequence-specific DNA binding
NIY06_04860	COG3961	Belongs to the TPP enzyme family
NIY06_04865	COG1113	amino acid transport
NIY06_04870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NIY06_04875	COG0573	inorganic phosphate transmembrane transporter activity
NIY06_04885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NIY06_04890	COG0616	signal peptide processing
NIY06_04925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NIY06_04930	COG1686	Belongs to the peptidase S11 family
NIY06_04955	COG0583	DNA-binding transcription factor activity
NIY06_04960	COG1067	ATP-dependent peptidase activity
NIY06_05005	COG1966	Carbon starvation protein
NIY06_05010	COG2879	small protein
NIY06_05045	COG2508	Transcriptional regulator
NIY06_05045	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NIY06_05065	COG1113	amino acid transport
NIY06_05070	COG0583	DNA-binding transcription factor activity
NIY06_05075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY06_05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY06_05090	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_05100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY06_05105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NIY06_05105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NIY06_05140	COG2814	Major facilitator Superfamily
NIY06_05145	COG4948	Mandelate Racemase Muconate Lactonizing
NIY06_05155	COG1309	transcriptional regulator
NIY06_05175	COG1741	Belongs to the pirin family
NIY06_05185	COG2964	Protein conserved in bacteria
NIY06_05200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY06_05205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIY06_05210	COG4605	iron ion homeostasis
NIY06_05215	COG4604	ABC transporter, ATP-binding protein
NIY06_05220	COG4607	ABC-type enterochelin transport system periplasmic component
NIY06_05225	COG4774	siderophore transport
NIY06_05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY06_05240	COG1021	2,3-dihydroxybenzoate-AMP ligase
NIY06_05245	COG1535	isochorismatase
NIY06_05245	COG3433	isochorismatase activity
NIY06_05260	COG1132	(ABC) transporter
NIY06_05265	COG1132	(ABC) transporter
NIY06_05270	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NIY06_05280	COG1169	isochorismate synthase
NIY06_05295	COG3739	integral membrane protein
NIY06_05320	COG0302	gtp cyclohydrolase
NIY06_05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NIY06_05360	COG0308	aminopeptidase N
NIY06_05365	COG0512	Glutamine amidotransferase of anthranilate synthase
NIY06_05380	COG0174	glutamine synthetase
NIY06_05390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NIY06_05425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NIY06_05430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIY06_05435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIY06_05455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NIY06_05460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NIY06_05465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NIY06_05480	COG1960	acyl-CoA dehydrogenase activity
NIY06_05485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIY06_05490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY06_05500	COG2223	nitrite transmembrane transporter activity
NIY06_05510	COG0024	Methionine aminopeptidase
NIY06_05515	COG0052	Belongs to the universal ribosomal protein uS2 family
NIY06_05530	COG2207	Transcriptional regulator
NIY06_05555	COG2951	lytic endotransglycosylase activity
NIY06_05560	COG0772	Belongs to the SEDS family
NIY06_05575	COG0842	Transport permease protein
NIY06_05580	COG1131	(ABC) transporter
NIY06_05625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY06_05640	COG4215	(ABC) transporter
NIY06_05645	COG4160	amino acid transport
NIY06_05650	COG4598	ABC transporter
NIY06_05660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY06_05665	COG0826	peptidase U32
NIY06_05670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY06_05685	COG1720	tRNA m6t6A37 methyltransferase activity
NIY06_05695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NIY06_05710	COG0642	Histidine kinase
NIY06_05720	COG0494	nUDIX hydrolase
NIY06_05730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NIY06_05735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIY06_05740	COG3139	Protein of unknown function (DUF1315)
NIY06_05745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIY06_05750	COG1301	dicarboxylic acid transport
NIY06_05755	COG1960	acyl-CoA dehydrogenase activity
NIY06_05760	COG2819	hydrolase of the alpha beta superfamily
NIY06_05770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NIY06_05780	COG2195	Cleaves the N-terminal amino acid of tripeptides
NIY06_05785	COG1234	tRNA 3'-trailer cleavage
NIY06_05815	COG2363	Small membrane protein
NIY06_05840	COG0513	Belongs to the DEAD box helicase family
NIY06_05850	COG0778	Nitroreductase
NIY06_06200	COG1286	toxin biosynthetic process
NIY06_06225	COG4783	chaperone-mediated protein folding
NIY06_06230	COG1610	YqeY-like protein
NIY06_06330	COG3111	PFAM Bacterial OB fold (BOF) protein
NIY06_06355	COG3243	poly(R)-hydroxyalkanoic acid synthase
NIY06_06360	COG0786	glutamate:sodium symporter activity
NIY06_06370	COG2186	Transcriptional regulator
NIY06_06420	COG0477	Major facilitator Superfamily
NIY06_06450	COG2985	domain, Protein
NIY06_06495	COG2026	Addiction module toxin, RelE StbE family
NIY06_06535	COG0592	DNA-directed DNA polymerase activity
NIY06_06625	COG1061	Type III restriction enzyme res subunit
NIY06_06635	COG1192	Involved in chromosome partitioning
NIY06_06640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NIY06_06650	COG1061	Type III restriction enzyme res subunit
NIY06_06680	COG0582	viral genome integration into host DNA
NIY06_06735	COG0629	single-stranded DNA binding
NIY06_06770	COG0084	hydrolase, TatD family'
NIY06_06790	COG0477	Major facilitator Superfamily
NIY06_06795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY06_06805	COG1595	DNA-templated transcription, initiation
NIY06_06860	COG0531	amino acid
NIY06_06865	COG2040	homocysteine
NIY06_06890	COG1309	transcriptional regulator
NIY06_06895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY06_06900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY06_06910	COG1607	acyl-coa hydrolase
NIY06_06920	COG0523	cobalamin synthesis protein
NIY06_06930	COG4681	YaeQ
NIY06_06940	COG0726	polysaccharide deacetylase
NIY06_06940	COG1649	PFAM Uncharacterised BCR, COG1649
NIY06_06945	COG1215	transferase activity, transferring glycosyl groups
NIY06_06955	COG1024	Enoyl-CoA hydratase
NIY06_06970	COG1414	Transcriptional regulator
NIY06_06990	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_07000	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY06_07005	COG2271	Major facilitator Superfamily
NIY06_07015	COG2267	carboxylic ester hydrolase activity
NIY06_07020	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_07035	COG0028	Belongs to the TPP enzyme family
NIY06_07045	COG0477	Major facilitator Superfamily
NIY06_07050	COG0242	peptide deformylase activity
NIY06_07055	COG2066	Belongs to the glutaminase family
NIY06_07060	COG2207	Transcriptional regulator
NIY06_07065	COG2223	nitrite transmembrane transporter activity
NIY06_07080	COG0583	DNA-binding transcription factor activity
NIY06_07085	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_07090	COG2271	Major facilitator Superfamily
NIY06_07095	COG3959	Transketolase, thiamine diphosphate binding domain
NIY06_07100	COG3958	Transketolase
NIY06_07110	COG0306	phosphate transporter
NIY06_07130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NIY06_07175	COG4181	ATPase activity
NIY06_07180	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NIY06_07205	COG0583	DNA-binding transcription factor activity
NIY06_07215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY06_07220	COG1773	rubredoxin
NIY06_07270	COG2851	Citrate transporter
NIY06_07275	COG1253	flavin adenine dinucleotide binding
NIY06_07315	COG0804	urea catabolic process
NIY06_07325	COG0830	nickel cation binding
NIY06_07340	COG0742	ribosomal rna small subunit methyltransferase
NIY06_07345	COG0768	penicillin binding
NIY06_07370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIY06_07375	COG2878	Part of a membrane complex involved in electron transport
NIY06_07380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NIY06_07390	COG3384	dioxygenase
NIY06_07415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIY06_07740	COG0739	heme binding
NIY06_07785	COG2194	sulfuric ester hydrolase activity
NIY06_07840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIY06_07855	COG0305	Participates in initiation and elongation during chromosome replication
NIY06_07955	COG4695	Portal protein
NIY06_08015	COG0741	lytic transglycosylase activity
NIY06_08015	COG0739	heme binding
NIY06_08015	COG1196	nuclear chromosome segregation
NIY06_08100	COG0006	proline dipeptidase activity
NIY06_08105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY06_08110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY06_08130	COG1279	arginine transmembrane transporter activity
NIY06_08135	COG0583	DNA-binding transcription factor activity
NIY06_08175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY06_08180	COG1388	LysM domain
NIY06_08180	COG0741	lytic transglycosylase activity
NIY06_08180	COG1388	LysM domain
NIY06_08180	COG0741	lytic transglycosylase activity
NIY06_08190	COG4174	ABC transporter (Permease)
NIY06_08195	COG4239	(ABC) transporter, permease
NIY06_08200	COG4172	Belongs to the ABC transporter superfamily
NIY06_08220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY06_08230	COG2203	Gaf domain
NIY06_08230	COG3706	GGDEF domain
NIY06_08230	COG4251	negative regulation of phosphorylation
NIY06_08230	COG5001	Diguanylate cyclase
NIY06_08240	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY06_08240	COG1902	pentaerythritol trinitrate reductase activity
NIY06_08255	COG4269	membrane
NIY06_08285	COG3209	COG3209 Rhs family protein
NIY06_08325	COG1113	amino acid transport
NIY06_08335	COG0531	amino acid
NIY06_08355	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_08405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NIY06_08530	COG1301	dicarboxylic acid transport
NIY06_08540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY06_08545	COG2011	ABC-type metal ion transport system permease component
NIY06_08550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIY06_08555	COG1464	Belongs to the NlpA lipoprotein family
NIY06_08560	COG0151	Belongs to the GarS family
NIY06_08565	COG0138	bifunctional purine biosynthesis protein purh
NIY06_08570	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NIY06_08600	COG2308	Evidence 4 Homologs of previously reported genes of
NIY06_08610	COG1305	Transglutaminase-like
NIY06_08620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIY06_08625	COG0305	Participates in initiation and elongation during chromosome replication
NIY06_08650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NIY06_08660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NIY06_08665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NIY06_08690	COG0726	polysaccharide deacetylase
NIY06_08690	COG1649	PFAM Uncharacterised BCR, COG1649
NIY06_08695	COG1215	transferase activity, transferring glycosyl groups
NIY06_08700	COG3658	cytochrome
NIY06_08710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY06_08725	COG0583	DNA-binding transcription factor activity
NIY06_08745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY06_08750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY06_08765	COG1960	acyl-CoA dehydrogenase activity
NIY06_08770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY06_08775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY06_08800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NIY06_08805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NIY06_08815	COG2205	protein histidine kinase activity
NIY06_08820	COG0745	RESPONSE REGULATOR receiver
NIY06_08825	COG0174	glutamine synthetase
NIY06_08845	COG0729	surface antigen
NIY06_08870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NIY06_08875	COG2814	Major facilitator Superfamily
NIY06_08890	COG0583	DNA-binding transcription factor activity
NIY06_08905	COG1187	pseudouridine synthase activity
NIY06_08925	COG0802	atpase or kinase
NIY06_08930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIY06_08945	COG1923	regulation of RNA biosynthetic process
NIY06_08950	COG0697	spore germination
NIY06_08965	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY06_08975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIY06_08980	COG0519	Catalyzes the synthesis of GMP from XMP
NIY06_08980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NIY06_08985	COG4302	ethanolamine ammonia-lyase activity
NIY06_08990	COG4303	Ethanolamine ammonia lyase large subunit
NIY06_08995	COG0531	amino acid
NIY06_09015	COG1454	alcohol dehydrogenase
NIY06_09020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NIY06_09030	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NIY06_09050	COG0308	aminopeptidase N
NIY06_09060	COG4221	oxidoreductase activity
NIY06_09070	COG1605	Chorismate mutase
NIY06_09090	COG1309	transcriptional regulator
NIY06_09100	COG0668	transmembrane transport
NIY06_09135	COG4773	Receptor
NIY06_09155	COG0488	(ABC) transporter
NIY06_09160	COG0589	response to stress
NIY06_09185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NIY06_09195	COG3135	benzoate transporter
NIY06_09200	COG1522	sequence-specific DNA binding
NIY06_09210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIY06_09215	COG0583	DNA-binding transcription factor activity
NIY06_09225	COG0183	Belongs to the thiolase family
NIY06_09235	COG2030	dehydratase
NIY06_09240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NIY06_09255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIY06_09265	COG0824	Thioesterase
NIY06_09270	COG1454	alcohol dehydrogenase
NIY06_09280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIY06_09300	COG0069	glutamate synthase activity
NIY06_09475	COG5410	chromosome segregation
NIY06_09615	COG1196	nuclear chromosome segregation
NIY06_09615	COG0741	lytic transglycosylase activity
NIY06_09615	COG0739	heme binding
NIY06_09685	COG2814	Major facilitator Superfamily
NIY06_09700	COG0511	ligase activity, forming carbon-carbon bonds
NIY06_09720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY06_09720	COG1116	anion transmembrane transporter activity
NIY06_09725	COG0745	RESPONSE REGULATOR receiver
NIY06_09735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY06_09735	COG2146	nitrite reductase [NAD(P)H] activity
NIY06_09740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY06_09745	COG0243	molybdopterin cofactor binding
NIY06_09755	COG0243	molybdopterin cofactor binding
NIY06_09760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NIY06_09775	COG0521	Mo-molybdopterin cofactor biosynthetic process
NIY06_09775	COG0315	cyclic pyranopterin monophosphate synthase activity
NIY06_09780	COG0303	'Molybdopterin
NIY06_09790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY06_09795	COG0697	spore germination
NIY06_09815	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NIY06_09820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIY06_09885	COG2204	response regulator
NIY06_09890	COG3852	Histidine kinase
NIY06_09910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIY06_09915	COG0575	Belongs to the CDS family
NIY06_09950	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY06_09965	COG2137	regulation of response to DNA damage stimulus
NIY06_09975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NIY06_09980	COG1011	Hydrolase
NIY06_10005	COG1522	sequence-specific DNA binding
NIY06_10015	COG1113	amino acid transport
NIY06_10035	COG0659	secondary active sulfate transmembrane transporter activity
NIY06_10040	COG2135	peptidase activity
NIY06_10055	COG3300	MHYT domain
NIY06_10055	COG5001	Diguanylate cyclase
NIY06_10075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NIY06_10075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NIY06_10075	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NIY06_10080	COG1105	Belongs to the carbohydrate kinase PfkB family
NIY06_10085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIY06_10085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIY06_10115	COG0024	Methionine aminopeptidase
NIY06_10120	COG0583	DNA-binding transcription factor activity
NIY06_10130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NIY06_10135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NIY06_10140	COG0516	GMP reductase activity
NIY06_10140	COG0517	IMP dehydrogenase activity
NIY06_10165	COG0552	protein localization to endoplasmic reticulum
NIY06_10175	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NIY06_10190	COG4890	Cyd operon protein YbgT
NIY06_10195	COG1294	oxidase, subunit
NIY06_10210	COG1585	Membrane protein implicated in regulation of membrane protease activity
NIY06_10220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIY06_10225	COG4774	siderophore transport
NIY06_10240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NIY06_10245	COG0569	domain protein
NIY06_10250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIY06_10280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NIY06_10285	COG0542	response to heat
NIY06_10310	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY06_10310	COG1902	pentaerythritol trinitrate reductase activity
NIY06_10355	COG2323	membrane
NIY06_10360	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NIY06_10370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY06_10375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY06_10380	COG0183	Belongs to the thiolase family
NIY06_10385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIY06_10390	COG0596	Alpha beta hydrolase
NIY06_10395	COG2271	Major facilitator Superfamily
NIY06_10400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIY06_10405	COG3485	protocatechuate 3,4-dioxygenase
NIY06_10410	COG3485	protocatechuate 3,4-dioxygenase
NIY06_10415	COG0710	3-dehydroquinate dehydratase activity
NIY06_10420	COG3420	alginic acid biosynthetic process
NIY06_10425	COG3659	wide pore channel activity
NIY06_10430	COG4993	Dehydrogenase
NIY06_10440	COG2391	methyltransferase activity
NIY06_10455	COG1414	Transcriptional regulator
NIY06_10460	COG0583	DNA-binding transcription factor activity
NIY06_10465	COG1960	acyl-CoA dehydrogenase activity
NIY06_10490	COG2814	Major facilitator Superfamily
NIY06_10500	COG0154	amidase activity
NIY06_10520	COG4638	Rieske (2fe-2S)
NIY06_10530	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_10540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY06_10550	COG3733	amine oxidase
NIY06_10560	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_10570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY06_10575	COG0183	Belongs to the thiolase family
NIY06_10580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY06_10585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY06_10595	COG4829	muconolactone delta-isomerase
NIY06_10600	COG4948	Mandelate Racemase Muconate Lactonizing
NIY06_10605	COG0583	DNA-binding transcription factor activity
NIY06_10615	COG2186	Transcriptional regulator
NIY06_10635	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_10655	COG1960	acyl-CoA dehydrogenase activity
NIY06_10660	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_10665	COG3829	transcription factor binding
NIY06_10675	COG3162	membrane
NIY06_10690	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_10705	COG0753	catalase activity
NIY06_10725	COG1846	Transcriptional regulator
NIY06_10730	COG1902	pentaerythritol trinitrate reductase activity
NIY06_10730	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY06_10740	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIY06_10770	COG1309	transcriptional regulator
NIY06_10780	COG1335	isochorismatase
NIY06_10785	COG0583	DNA-binding transcription factor activity
NIY06_10795	COG0475	glutathione-regulated potassium exporter activity
NIY06_10795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY06_10805	COG1473	amidohydrolase
NIY06_10815	COG2831	hemolysin activation secretion protein
NIY06_10820	COG3210	domain, Protein
NIY06_10850	COG2188	Transcriptional regulator
NIY06_10865	COG0583	DNA-binding transcription factor activity
NIY06_10895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NIY06_10925	COG1566	PFAM secretion protein HlyD family protein
NIY06_10940	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_10945	COG0129	dihydroxy-acid dehydratase activity
NIY06_10955	COG0583	DNA-binding transcription factor activity
NIY06_10960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NIY06_10970	COG2084	Dehydrogenase
NIY06_10975	COG2207	Transcriptional regulator
NIY06_10990	COG1064	alcohol dehydrogenase
NIY06_11000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIY06_11005	COG1120	ATPase activity
NIY06_11025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIY06_11145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NIY06_11195	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_11210	COG2207	Transcriptional regulator
NIY06_11225	COG0745	RESPONSE REGULATOR receiver
NIY06_11230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY06_11235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY06_11240	COG1538	Outer membrane efflux protein
NIY06_11250	COG2072	flavoprotein involved in K transport
NIY06_11270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NIY06_11290	COG3539	Fimbrial protein
NIY06_11320	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NIY06_11330	COG0753	catalase activity
NIY06_11345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIY06_11405	COG1535	isochorismatase
NIY06_11405	COG3433	isochorismatase activity
NIY06_11410	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_11415	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NIY06_11420	COG4149	molybdate abc transporter
NIY06_11425	COG0725	ABC transporter, periplasmic molybdate-binding protein
NIY06_11435	COG4638	Rieske (2fe-2S)
NIY06_11440	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NIY06_11445	COG0543	2 iron, 2 sulfur cluster binding
NIY06_11445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY06_11470	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_11485	COG2207	Transcriptional regulator
NIY06_11495	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_11500	COG2610	gluconate transmembrane transporter activity
NIY06_11510	COG0583	DNA-binding transcription factor activity
NIY06_11520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY06_11525	COG2031	fatty acid transporter
NIY06_11530	COG0183	Belongs to the thiolase family
NIY06_11535	COG0583	DNA-binding transcription factor activity
NIY06_11540	COG0583	DNA-binding transcription factor activity
NIY06_11555	COG1027	Aspartate ammonia-lyase
NIY06_11565	COG0477	Major facilitator Superfamily
NIY06_11585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY06_11590	COG4521	taurine ABC transporter
NIY06_11605	COG2188	Transcriptional regulator
NIY06_11615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIY06_11620	COG1733	regulation of RNA biosynthetic process
NIY06_11625	COG2207	Transcriptional regulator
NIY06_11625	COG3708	Transcriptional regulator
NIY06_11640	COG0730	response to heat
NIY06_11655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY06_11655	COG3453	Protein conserved in bacteria
NIY06_11665	COG3781	membrane
NIY06_11670	COG1063	alcohol dehydrogenase
NIY06_11680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY06_11685	COG0508	dehydrogenase complex catalyzes the overall conversion of
NIY06_11690	COG0022	dehydrogenase e1 component
NIY06_11695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NIY06_11700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIY06_11715	COG3706	GGDEF domain
NIY06_11730	COG0133	tryptophan synthase activity
NIY06_11740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIY06_11775	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIY06_11800	COG2226	methyltransferase
NIY06_11855	COG0842	Transport permease protein
NIY06_11860	COG0842	Transport permease protein
NIY06_11865	COG1131	(ABC) transporter
NIY06_11880	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY06_11885	COG4773	Receptor
NIY06_11905	COG0730	response to heat
NIY06_11910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIY06_11930	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NIY06_11945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NIY06_11985	COG4264	IucA IucC family
NIY06_11990	COG4264	IucA IucC family
NIY06_12010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIY06_12025	COG1960	acyl-CoA dehydrogenase activity
NIY06_12030	COG1960	acyl-CoA dehydrogenase activity
NIY06_12035	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY06_12040	COG2207	Transcriptional regulator
NIY06_12045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NIY06_12050	COG0776	regulation of translation
NIY06_12075	COG0822	iron-sulfur transferase activity
NIY06_12080	COG0316	Belongs to the HesB IscA family
NIY06_12110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIY06_12140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NIY06_12145	COG0702	epimerase
NIY06_12180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIY06_12190	COG0339	signal peptide processing
NIY06_12240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NIY06_12245	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NIY06_12275	COG0776	regulation of translation
NIY06_12340	COG0084	hydrolase, TatD family'
NIY06_12360	COG1663	tetraacyldisaccharide 4'-kinase activity
NIY06_12365	COG1132	(ABC) transporter
NIY06_12375	COG0811	peptide transport
NIY06_12380	COG1475	DNA binding
NIY06_12385	COG1192	Involved in chromosome partitioning
NIY06_12395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NIY06_12410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NIY06_12415	COG0191	fructose-bisphosphate aldolase activity
NIY06_12435	COG0424	maF-like protein
NIY06_12440	COG2850	peptidyl-arginine hydroxylation
NIY06_12460	COG0640	Transcriptional regulator
NIY06_12470	COG3619	membrane
NIY06_12475	COG3122	Protein conserved in bacteria
NIY06_12480	COG1132	(ABC) transporter
NIY06_12500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NIY06_12505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIY06_12515	COG0506	proline dehydrogenase activity
NIY06_12515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NIY06_12515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NIY06_12520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIY06_12535	COG3698	Phosphodiester glycosidase
NIY06_12545	COG2353	YceI-like domain
NIY06_12555	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIY06_12600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIY06_12600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NIY06_12625	COG3539	Fimbrial protein
NIY06_12630	COG3121	Chaperone
NIY06_12655	COG0697	spore germination
NIY06_12665	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NIY06_12675	COG0583	DNA-binding transcription factor activity
NIY06_12695	COG1309	transcriptional regulator
NIY06_12710	COG1522	sequence-specific DNA binding
NIY06_12725	COG1126	abc transporter atp-binding protein
NIY06_12730	COG0765	amino acid transport
NIY06_12735	COG0765	amino acid transport
NIY06_12765	COG1464	Belongs to the NlpA lipoprotein family
NIY06_12775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIY06_12780	COG2011	ABC-type metal ion transport system permease component
NIY06_12785	COG0012	GTP binding
NIY06_12810	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NIY06_12850	COG0386	Belongs to the glutathione peroxidase family
NIY06_12860	COG0436	Aminotransferase
NIY06_12900	COG3634	alkyl hydroperoxide reductase activity
NIY06_12915	COG0583	DNA-binding transcription factor activity
NIY06_12920	COG0798	PFAM Bile acid sodium symporter
NIY06_12925	COG0640	Transcriptional regulator
NIY06_12940	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NIY06_12950	COG0583	DNA-binding transcription factor activity
NIY06_12960	COG1953	Uracil, thiamine, allantoin
NIY06_12970	COG2175	clavaminate synthase activity
NIY06_12975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY06_12980	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NIY06_12985	COG4521	taurine ABC transporter
NIY06_12995	COG0477	Major facilitator Superfamily
NIY06_13015	COG1271	oxidase subunit
NIY06_13020	COG1294	oxidase, subunit
NIY06_13030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY06_13050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NIY06_13070	COG3052	prosthetic group binding
NIY06_13075	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NIY06_13085	COG2814	Major facilitator Superfamily
NIY06_13105	COG1346	cytolysis
NIY06_13115	COG0583	DNA-binding transcription factor activity
NIY06_13120	COG0625	glutathione transferase activity
NIY06_13125	COG0625	glutathione transferase activity
NIY06_13130	COG0583	DNA-binding transcription factor activity
NIY06_13145	COG1045	serine acetyltransferase
NIY06_13150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NIY06_13155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIY06_13165	COG1280	lysine exporter protein (LysE YggA)
NIY06_13180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY06_13185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY06_13190	COG1126	abc transporter atp-binding protein
NIY06_13195	COG0765	amino acid transport
NIY06_13200	COG0765	amino acid transport
NIY06_13220	COG2205	protein histidine kinase activity
NIY06_13220	COG0784	Response regulator, receiver
NIY06_13240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIY06_13260	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_13310	COG0583	DNA-binding transcription factor activity
NIY06_13335	COG0318	PFAM AMP-dependent synthetase and ligase
NIY06_13340	COG1309	transcriptional regulator
NIY06_13345	COG1960	acyl-CoA dehydrogenase activity
NIY06_13350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NIY06_13355	COG1024	Enoyl-CoA hydratase
NIY06_13360	COG4770	biotin carboxylase activity
NIY06_13370	COG0583	DNA-binding transcription factor activity
NIY06_13385	COG1960	acyl-CoA dehydrogenase activity
NIY06_13395	COG2814	Major facilitator Superfamily
NIY06_13405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY06_13410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY06_13415	COG2814	Major facilitator Superfamily
NIY06_13420	COG1960	acyl-CoA dehydrogenase activity
NIY06_13425	COG1024	Enoyl-CoA hydratase
NIY06_13430	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_13435	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY06_13440	COG0183	Belongs to the thiolase family
NIY06_13450	COG2814	Major facilitator Superfamily
NIY06_13460	COG1024	Enoyl-CoA hydratase
NIY06_13475	COG1960	acyl-CoA dehydrogenase activity
NIY06_13480	COG2814	Major facilitator Superfamily
NIY06_13485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NIY06_13490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NIY06_13505	COG3842	ATPase activity
NIY06_13510	COG1840	ABC-type Fe3 transport system, periplasmic component
NIY06_13520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY06_13525	COG1414	Transcriptional regulator
NIY06_13535	COG0583	DNA-binding transcription factor activity
NIY06_13540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIY06_13545	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_13555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NIY06_13565	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_13570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY06_13575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY06_13580	COG2267	carboxylic ester hydrolase activity
NIY06_13600	COG3038	cytochrome b561
NIY06_13605	COG0753	catalase activity
NIY06_13640	COG2050	protein possibly involved in aromatic compounds catabolism
NIY06_13650	COG3327	negative regulation of DNA-templated transcription, initiation
NIY06_13655	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NIY06_13660	COG0183	Belongs to the thiolase family
NIY06_13665	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY06_13670	COG1024	Enoyl-CoA hydratase
NIY06_13675	COG1024	Enoyl-CoA hydratase
NIY06_13680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY06_13685	COG2151	metal-sulfur cluster biosynthetic enzyme
NIY06_13690	COG3396	Phenylacetate-CoA oxygenase
NIY06_13695	COG3460	Phenylacetate-CoA oxygenase
NIY06_13700	COG3396	Phenylacetate-CoA oxygenase
NIY06_13705	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_13705	COG2030	dehydratase
NIY06_13710	COG1760	l-serine dehydratase
NIY06_13715	COG0531	amino acid
NIY06_13720	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_13735	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY06_13745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NIY06_13765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY06_13775	COG0789	Transcriptional regulator
NIY06_13790	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NIY06_13805	COG2807	transmembrane transport
NIY06_13810	COG0590	tRNA wobble adenosine to inosine editing
NIY06_13930	COG1116	anion transmembrane transporter activity
NIY06_13935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY06_13945	COG0864	Transcriptional regulator
NIY06_13965	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY06_13970	COG0439	Biotin carboxylase
NIY06_13985	COG1063	alcohol dehydrogenase
NIY06_13995	COG1309	transcriptional regulator
NIY06_14015	COG0038	chloride channel
NIY06_14020	COG4770	biotin carboxylase activity
NIY06_14040	COG1914	H( )-stimulated, divalent metal cation uptake system
NIY06_14045	COG0583	DNA-binding transcription factor activity
NIY06_14095	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY06_14115	COG2814	Major facilitator Superfamily
NIY06_14130	COG1560	Kdo2-lipid A biosynthetic process
NIY06_14140	COG5006	permease, DMT superfamily
NIY06_14145	COG1522	sequence-specific DNA binding
NIY06_14160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NIY06_14170	COG4122	O-methyltransferase activity
NIY06_14200	COG1538	Outer membrane efflux protein
NIY06_14205	COG1137	ATPase activity
NIY06_14210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NIY06_14220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NIY06_14225	COG0517	IMP dehydrogenase activity
NIY06_14225	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NIY06_14260	COG2814	Major facilitator Superfamily
NIY06_14295	COG1278	Cold shock
NIY06_14300	COG1280	lysine exporter protein (LysE YggA)
NIY06_14330	COG1570	exodeoxyribonuclease VII activity
NIY06_14380	COG0583	DNA-binding transcription factor activity
NIY06_14390	COG4638	Rieske (2fe-2S)
NIY06_14395	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NIY06_14400	COG0543	2 iron, 2 sulfur cluster binding
NIY06_14400	COG0633	Ferredoxin
NIY06_14405	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_14410	COG3135	benzoate transporter
NIY06_14415	COG2814	Major facilitator Superfamily
NIY06_14430	COG1643	Atp-dependent helicase
NIY06_14435	COG0450	alkyl hydroperoxide reductase
NIY06_14445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NIY06_14455	COG3634	alkyl hydroperoxide reductase activity
NIY06_14475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NIY06_14480	COG0625	glutathione transferase activity
NIY06_14490	COG2885	chlorophyll binding
NIY06_14525	COG0542	response to heat
NIY06_14540	COG1765	OsmC-like protein
NIY06_14560	COG0667	Aldo Keto reductase
NIY06_14575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIY06_14585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NIY06_14595	COG0527	aspartate kinase activity
NIY06_14605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIY06_14615	COG3038	cytochrome b561
NIY06_14620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NIY06_14625	COG2252	PERMEase
NIY06_14635	COG2072	flavoprotein involved in K transport
NIY06_14650	COG1741	Belongs to the pirin family
NIY06_14655	COG1309	transcriptional regulator
NIY06_14790	COG3755	Protein conserved in bacteria
NIY06_14835	COG1484	DNA-dependent DNA replication
NIY06_14925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY06_14995	COG0405	Gamma-glutamyltransferase
NIY06_15000	COG2814	Major facilitator Superfamily
NIY06_15010	COG2050	protein possibly involved in aromatic compounds catabolism
NIY06_15025	COG1090	epimerase
NIY06_15045	COG0420	3'-5' exonuclease activity
NIY06_15070	COG0735	belongs to the Fur family
NIY06_15075	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NIY06_15095	COG0121	glutamine amidotransferase
NIY06_15110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIY06_15120	COG0210	DNA helicase
NIY06_15125	COG2885	chlorophyll binding
NIY06_15130	COG0204	Acyl-transferase
NIY06_15145	COG2894	cell division
NIY06_15165	COG1280	lysine exporter protein (LysE YggA)
NIY06_15170	COG1674	ftsk spoiiie
NIY06_15170	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIY06_15175	COG0492	ferredoxin-NADP+ reductase activity
NIY06_15180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NIY06_15190	COG0456	acetyltransferase
NIY06_15235	COG1981	membrane
NIY06_15250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIY06_15250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NIY06_15270	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_15280	COG0657	acetylesterase activity
NIY06_15290	COG0473	3-isopropylmalate dehydrogenase activity
NIY06_15295	COG0583	DNA-binding transcription factor activity
NIY06_15315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY06_15340	COG0564	pseudouridine synthase activity
NIY06_15350	COG0358	DNA primase activity
NIY06_15365	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NIY06_15395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIY06_15425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NIY06_15435	COG0351	phosphomethylpyrimidine kinase
NIY06_15435	COG0352	thiamine-phosphate diphosphorylase activity
NIY06_15435	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIY06_15440	COG1652	LysM domain
NIY06_15465	COG1399	metal-binding, possibly nucleic acid-binding protein
NIY06_15470	COG3101	peptidyl-lysine hydroxylation
NIY06_15475	COG0009	L-threonylcarbamoyladenylate synthase
NIY06_15480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIY06_15485	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIY06_15500	COG4106	trans-aconitate 2-methyltransferase activity
NIY06_15515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY06_15515	COG2226	methyltransferase
NIY06_15515	COG0596	Alpha beta hydrolase
NIY06_15520	COG1877	trehalose-phosphatase activity
NIY06_15525	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NIY06_15530	COG2223	nitrite transmembrane transporter activity
NIY06_15550	COG1196	nuclear chromosome segregation
NIY06_15560	COG0730	response to heat
NIY06_15575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIY06_15585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIY06_15645	COG0489	protein tyrosine kinase activity
NIY06_15655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY06_15655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY06_15685	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NIY06_15690	COG2081	HI0933 family
NIY06_15700	COG0668	transmembrane transport
NIY06_15720	COG0583	DNA-binding transcription factor activity
NIY06_15740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NIY06_15745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NIY06_15775	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NIY06_15815	COG0745	RESPONSE REGULATOR receiver
NIY06_15835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIY06_15845	COG2205	protein histidine kinase activity
NIY06_15915	COG4993	Dehydrogenase
NIY06_15940	COG0384	phenazine biosynthesis protein PhzF
NIY06_15965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY06_15980	COG0583	DNA-binding transcription factor activity
NIY06_16010	COG0583	DNA-binding transcription factor activity
NIY06_16025	COG0583	DNA-binding transcription factor activity
NIY06_16030	COG1053	succinate dehydrogenase
NIY06_16040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NIY06_16045	COG2814	Major facilitator Superfamily
NIY06_16050	COG1960	acyl-CoA dehydrogenase activity
NIY06_16055	COG0583	DNA-binding transcription factor activity
NIY06_16060	COG1063	alcohol dehydrogenase
NIY06_16090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NIY06_16095	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIY06_16100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIY06_16115	COG3667	copper resistance
NIY06_16120	COG2132	Multicopper oxidase
NIY06_16130	COG0561	phosphatase activity
NIY06_16135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NIY06_16160	COG1214	PFAM Peptidase M22, glycoprotease
NIY06_16210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIY06_16220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIY06_16225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NIY06_16230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIY06_16290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIY06_16300	COG1846	Transcriptional regulator
NIY06_16305	COG1764	response to oxidative stress
NIY06_16345	COG0037	tRNA processing
NIY06_16355	COG0248	Ppx GppA phosphatase
NIY06_16385	COG0072	phenylalanine-tRNA ligase activity
NIY06_16430	COG1238	metal cluster binding
NIY06_16435	COG0625	glutathione transferase activity
NIY06_16450	COG0318	PFAM AMP-dependent synthetase and ligase
NIY06_16455	COG3028	Belongs to the UPF0307 family
NIY06_16460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIY06_16480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NIY06_16485	COG0617	tRNA 3'-terminal CCA addition
NIY06_16490	COG1555	photosystem II stabilization
NIY06_16495	COG3956	TIGRFAM MazG family protein
NIY06_16505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIY06_16525	COG0784	Response regulator, receiver
NIY06_16525	COG2205	protein histidine kinase activity
NIY06_16525	COG5002	protein histidine kinase activity
NIY06_16530	COG1024	Enoyl-CoA hydratase
NIY06_16535	COG2084	Dehydrogenase
NIY06_16540	COG3622	Belongs to the hyi family
NIY06_16570	COG0697	spore germination
NIY06_16580	COG2814	Major facilitator Superfamily
NIY06_16585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIY06_16595	COG0583	DNA-binding transcription factor activity
NIY06_16605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NIY06_16620	COG0084	hydrolase, TatD family'
NIY06_16635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIY06_16665	COG0440	acetolactate synthase activity
NIY06_16670	COG0028	Belongs to the TPP enzyme family
NIY06_16695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY06_16700	COG1136	(ABC) transporter
NIY06_16700	COG0577	efflux transmembrane transporter activity
NIY06_16705	COG1538	Outer membrane efflux protein
NIY06_16720	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NIY06_16725	COG1162	GTPase activity
NIY06_16735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NIY06_16755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NIY06_16760	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_16800	COG2986	histidine ammonia-lyase
NIY06_16815	COG0318	PFAM AMP-dependent synthetase and ligase
NIY06_16825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIY06_16870	COG1426	Protein conserved in bacteria
NIY06_16905	COG0793	Belongs to the peptidase S41A family
NIY06_16920	COG2267	carboxylic ester hydrolase activity
NIY06_16930	COG1012	belongs to the aldehyde dehydrogenase family
NIY06_16935	COG3265	gluconokinase activity
NIY06_16945	COG0800	Aldolase
NIY06_16955	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIY06_16960	COG0857	belongs to the CobB CobQ family
NIY06_16960	COG0280	phosphate acetyltransferase
NIY06_16965	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NIY06_16965	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NIY06_16985	COG0740	serine-type endopeptidase activity
NIY06_16995	COG4774	siderophore transport
NIY06_17005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIY06_17015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY06_17015	COG2813	Specifically methylates the guanine in position
NIY06_17115	COG0788	formyltetrahydrofolate deformylase activity
NIY06_17140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY06_17140	COG4651	solute:proton antiporter activity
NIY06_17160	COG0724	RNA recognition motif
NIY06_17165	COG0210	DNA helicase
NIY06_17190	COG1733	regulation of RNA biosynthetic process
NIY06_17200	COG2900	Belongs to the SlyX family
NIY06_17205	COG0488	(ABC) transporter
NIY06_17210	COG1280	lysine exporter protein (LysE YggA)
NIY06_17215	COG1560	Kdo2-lipid A biosynthetic process
NIY06_17225	COG1301	dicarboxylic acid transport
NIY06_17280	COG0473	3-isopropylmalate dehydrogenase activity
NIY06_17345	COG0583	DNA-binding transcription factor activity
NIY06_17355	COG0625	glutathione transferase activity
NIY06_17360	COG2378	regulation of single-species biofilm formation
NIY06_17365	COG0546	phosphoglycolate phosphatase activity
NIY06_17375	COG1530	ribonuclease E activity
NIY06_17380	COG0318	PFAM AMP-dependent synthetase and ligase
NIY06_17395	COG0583	DNA-binding transcription factor activity
NIY06_17400	COG4221	oxidoreductase activity
NIY06_17405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NIY06_17415	COG0534	Mate efflux family protein
NIY06_17430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NIY06_17470	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NIY06_17475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY06_17490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NIY06_17500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NIY06_17500	COG0644	oxidoreductase
NIY06_17505	COG0425	Belongs to the sulfur carrier protein TusA family
NIY06_17510	COG4535	Mg2 and Co2 transporter CorC
NIY06_17520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY06_17540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIY06_17545	COG0475	glutathione-regulated potassium exporter activity
NIY06_17545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY06_17550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIY06_17560	COG0484	heat shock protein binding
NIY06_17565	COG0789	Transcriptional regulator
NIY06_17570	COG0598	Magnesium transport protein CorA
NIY06_17585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NIY06_17590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NIY06_17595	COG1074	ATP-dependent DNA helicase activity
NIY06_17600	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NIY06_17620	COG2226	methyltransferase
NIY06_17635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY06_17640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIY06_17655	COG2111	Na H antiporter
NIY06_17655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NIY06_17660	COG1006	Multisubunit Na H antiporter MnhC subunit
NIY06_17665	COG0651	ATP synthesis coupled electron transport
NIY06_17670	COG1863	multisubunit Na H antiporter MnhE subunit
NIY06_17675	COG2212	antiporter activity
NIY06_17680	COG1320	monovalent cation:proton antiporter activity
NIY06_17695	COG0195	Participates in both transcription termination and antitermination
NIY06_17745	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NIY06_17750	COG0237	dephospho-CoA kinase activity
NIY06_17760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIY06_17775	COG0497	DNA recombination
NIY06_17785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIY06_17815	COG2169	Transcriptional regulator
NIY06_17815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIY06_17820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIY06_17885	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NIY06_17900	COG0326	Molecular chaperone. Has ATPase activity
NIY06_17915	COG2056	Na+-H+ antiporter family
NIY06_17920	COG0596	Alpha beta hydrolase
NIY06_18015	COG0546	phosphoglycolate phosphatase activity
NIY06_18020	COG1716	ATPase activity
NIY06_18065	COG0181	hydroxymethylbilane synthase activity
NIY06_18075	COG3275	phosphorelay sensor kinase activity
NIY06_18095	COG1538	Outer membrane efflux protein
NIY06_18100	COG0697	spore germination
NIY06_18125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIY06_18130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NIY06_18135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIY06_18140	COG0772	Belongs to the SEDS family
NIY06_18165	COG4974	Belongs to the 'phage' integrase family
NIY06_18170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY06_18180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NIY06_18190	COG2197	response regulator
NIY06_18205	COG0793	Belongs to the peptidase S41A family
NIY06_18210	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIY06_18215	COG0795	lipopolysaccharide-transporting ATPase activity
NIY06_18255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIY06_18255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIY06_18265	COG0004	ammonium transporteR
NIY06_18270	COG0347	Belongs to the P(II) protein family
NIY06_18330	COG0659	secondary active sulfate transmembrane transporter activity
NIY06_18335	COG0589	response to stress
NIY06_18370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY06_18380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY06_18400	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NIY06_18415	COG0318	PFAM AMP-dependent synthetase and ligase
NIY06_18425	COG0477	Major facilitator Superfamily
NIY06_18430	COG2860	membrane
NIY06_18440	COG1253	flavin adenine dinucleotide binding
NIY06_18460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIY06_18500	COG0655	NAD(P)H dehydrogenase (quinone) activity
NIY06_18510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NIY06_18580	COG0758	DNA mediated transformation
NIY06_18590	COG0697	spore germination
NIY06_18595	COG1309	transcriptional regulator
NIY06_18610	COG0386	Belongs to the glutathione peroxidase family
NIY06_18675	COG1121	(ABC) transporter
NIY06_18680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NIY06_18685	COG1280	lysine exporter protein (LysE YggA)
NIY06_18690	COG2837	iron assimilation
NIY06_18700	COG0281	malic enzyme
NIY06_18745	COG0519	Catalyzes the synthesis of GMP from XMP
NIY06_18745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NIY06_18750	COG4399	Belongs to the UPF0754 family
NIY06_18755	COG2259	Doxx family
NIY06_18760	COG0586	Pfam SNARE associated Golgi protein
NIY06_18775	COG1192	Involved in chromosome partitioning
NIY06_18785	COG0271	Belongs to the BolA IbaG family
NIY06_18805	COG2267	carboxylic ester hydrolase activity
NIY06_18825	COG3321	synthase
NIY06_18825	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NIY06_18825	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NIY06_18825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIY06_18830	COG1960	acyl-CoA dehydrogenase activity
NIY06_18840	COG2197	response regulator
NIY06_18850	COG3916	Acyl-homoserine-lactone synthase
NIY06_18855	COG0477	Major facilitator Superfamily
NIY06_18860	COG1024	Enoyl-CoA hydratase
NIY06_18865	COG1024	Enoyl-CoA hydratase
NIY06_18870	COG1960	acyl-CoA dehydrogenase activity
NIY06_18875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY06_18895	COG1113	amino acid transport
NIY06_18900	COG1113	amino acid transport
NIY06_18905	COG0251	oxidation-reduction process
NIY06_18945	COG0564	pseudouridine synthase activity
NIY06_19005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIY06_19020	COG1802	Transcriptional regulator
NIY06_19030	COG1448	Aminotransferase
NIY06_19035	COG0277	FAD linked oxidase domain protein
NIY06_19045	COG2186	Transcriptional regulator
NIY06_19055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIY06_19060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIY06_19075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NIY06_19080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NIY06_19085	COG1216	Glycosyl transferase, family 2
NIY06_19115	COG2089	acid synthase
NIY06_19130	COG1083	cytidylyl-transferase
NIY06_19135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NIY06_19140	COG1086	Polysaccharide biosynthesis protein
NIY06_19145	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NIY06_19150	COG1596	polysaccharide export
NIY06_19175	COG0728	peptidoglycan biosynthetic process
NIY06_19180	COG3023	N-Acetylmuramoyl-L-alanine amidase
NIY06_19235	COG0546	phosphoglycolate phosphatase activity
NIY06_19240	COG1028	Short-chain dehydrogenase reductase Sdr
NIY06_19260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY06_19265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY06_19270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY06_19275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY06_19280	COG1116	anion transmembrane transporter activity
NIY06_19285	COG1309	transcriptional regulator
NIY06_19290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIY06_19300	COG0196	riboflavin kinase activity
NIY06_19305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIY06_19315	COG1047	Peptidyl-prolyl cis-trans
NIY06_19355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIY06_19360	COG0657	acetylesterase activity
NIY06_19380	COG0583	DNA-binding transcription factor activity
NIY06_19410	COG2951	lytic endotransglycosylase activity
NIY06_19415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIY06_19430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NIY06_19440	COG0671	phosphoesterase, PA-phosphatase related
NIY06_19445	COG0861	Integral membrane protein TerC family
NIY06_19455	COG0754	glutathionylspermidine amidase activity
NIY06_19465	COG0402	S-adenosylhomocysteine deaminase activity
NIY06_19480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY06_19485	COG1230	cation diffusion facilitator family transporter
NIY06_19500	COG0706	membrane insertase activity