locus-tag class description IX87_00195 ENOG4105CDU Replicative dna helicase IX87_00320 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase IX87_00355 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b IX87_00365 ENOG4105D82 Glutamate dehydrogenase IX87_00370 ENOG4108R3D Electron transport complex IX87_00375 ENOG4105CSM endonuclease III IX87_00400 ENOG4105CJN penicillin-binding protein IX87_00405 ENOG4106H78 methyltransferase IX87_00420 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) IX87_00430 ENOG4105CQM Urea amidohydrolase subunit alpha IX87_00470 ENOG4107RET Isocitrate lyase IX87_00480 ENOG4105C37 (CBS) domain IX87_00495 ENOG4105D4T Citrate transporter IX87_00510 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) IX87_00525 ENOG4108MRJ IX87_00555 ENOG4105VCQ rubredoxin IX87_00560 ENOG4107QZF nitrite reductase NADPH large subunit IX87_00570 ENOG4105C5Q Transcriptional regulator IX87_00590 ENOG4107U91 Rhomboid family IX87_00600 ENOG4108I0Y (ABC) transporter IX87_00605 ENOG4108UJV acyl-CoA thioesterase i IX87_00625 ENOG4107RNH Outer membrane receptor FepA IX87_00640 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) IX87_00645 ENOG4105E6M Sulphatase-modifying factor protein IX87_00665 ENOG4105CJ3 phosphate transporter IX87_00675 ENOG4105C3R Methionine synthase IX87_00690 ENOG4105CSP Major Facilitator Superfamily IX87_00700 ENOG4108PZW LysR family Transcriptional regulator IX87_00710 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) IX87_00715 ENOG4105EU0 Major facilitator Superfamily IX87_00720 ENOG4108R6W Transcriptional regulator, ARAC family IX87_00725 ENOG4105CSV Glutaminase IX87_00730 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) IX87_00735 ENOG4105CSH Transporter IX87_00745 ENOG4105C7K acetolactate synthase IX87_00750 ENOG4105C26 Dehydrogenase IX87_00760 ENOG4105CHR reductase IX87_00765 ENOG4108MXF Alpha Beta Hydrolase IX87_00775 ENOG4105DJB Major Facilitator Superfamily IX87_00790 ENOG4105CHR reductase IX87_00810 ENOG41069M3 Transcriptional regulator IX87_00825 ENOG4106YT9 Enoyl-CoA hydratase IX87_00835 ENOG4105CND Glycosyl transferase, family 2 IX87_00840 ENOG4107BJW polysaccharide deacetylase IX87_00850 ENOG4108VWS Yaeq family IX87_00860 ENOG4105CKI cobalamin synthesis protein IX87_00880 ENOG4105C94 Transporter IX87_00885 ENOG4105C94 Transporter IX87_00890 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) IX87_00925 ENOG4107QK5 Homocysteine s-methyltransferase IX87_00930 ENOG4105D5Q Arginine ornithine antiporter IX87_00955 ENOG4108YNN Heme oxygenase IX87_00985 ENOG4108SF5 RNA Polymerase IX87_00995 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) IX87_01000 ENOG4105C54 Major Facilitator superfamily IX87_01010 ENOG4107SCJ type I restriction enzyme EcoKI subunit R IX87_01110 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) IX87_01185 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) IX87_01225 ENOG4105K4U addiction module toxin, RelE StbE family IX87_01540 ENOG41083X2 DNA polymerase III, epsilon subunit IX87_01600 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) IX87_01605 ENOG4105C0R drug resistance transporter emrb qaca subfamily IX87_01610 ENOG4105CW7 secretion protein, HlyD family IX87_01615 ENOG4108VUY thioesterase Superfamily protein IX87_01620 ENOG4105D52 delta-aminolevulinic acid dehydratase IX87_01625 ENOG4105MWK D-amino acid dehydrogenase, small subunit IX87_01630 ENOG4105ECP epimerase IX87_01650 ENOG4107RH8 nuclease SbcCD subunit D IX87_01655 ENOG4105EYH Exonuclease IX87_01665 ENOG4105DFA alanine racemase domain protein IX87_01670 ENOG4105CZX twitching motility protein IX87_01675 ENOG4105CZX twitching motility protein IX87_01680 ENOG41090R7 Ferric uptake IX87_01705 ENOG4105E7A Glutamine amidotransferase IX87_01720 ENOG4107QKV phosphomannomutase IX87_01730 ENOG4105C4R Atp-dependent dna helicase IX87_01735 ENOG4108ZG0 Ompa motb domain protein IX87_01740 ENOG4106HNH Acyl-transferase IX87_01755 ENOG4107QMS site-determining protein IX87_01775 ENOG4105CNU cell division protein FtsK IX87_01780 ENOG4105C3M thioredoxin reductase IX87_01785 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) IX87_01795 ENOG4105KEG ribosomal-protein-alanine acetyltransferase IX87_01855 ENOG4108YXA Membrane IX87_01860 ENOG4105EUB pirin domain protein IX87_01870 ENOG4105C4K Nad synthetase IX87_01885 ENOG4105E3J oxidoreductase IX87_01890 ENOG4105C26 Dehydrogenase IX87_01895 ENOG4105DVW rieske (2Fe-2S) IX87_01905 ENOG4105C94 Transporter IX87_01910 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) IX87_01915 ENOG4105EJC lysr family transcriptional regulator IX87_01930 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding IX87_01940 ENOG4105DFP Integrase IX87_01995 ENOG4105E4C Lytic transglycosylase catalytic IX87_02145 ENOG4105CDU Replicative dna helicase IX87_02165 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) IX87_02215 ENOG4105D6Z AFG1 family ATPase IX87_02255 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) IX87_02260 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) IX87_02275 ENOG4108Z6B deaminase IX87_02295 ENOG4108RTD type II secretion system protein K IX87_02320 ENOG4105F8V Hydrolase, tatD family IX87_02330 ENOG4107QRG dna polymerase iii IX87_02340 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) IX87_02345 ENOG4105BZ1 (ABC) transporter IX87_02360 ENOG4105FA0 parb-like partition protein IX87_02365 ENOG4107QJE Chromosome Partitioning Protein IX87_02375 ENOG4108S0S Nucleotidyl transferase IX87_02380 ENOG4105EHM Aminoglycoside phosphotransferase IX87_02385 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) IX87_02390 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) IX87_02395 ENOG4105D2N Aldolase IX87_02415 ENOG4108UHJ MAF-like protein IX87_02420 ENOG4105EZE Cupin 4 family protein IX87_02430 ENOG41080HT Transcriptional regulator, arsr family IX87_02440 ENOG4105XPP Protein of unknown function (DUF1275) IX87_02445 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme IX87_02460 ENOG4105BZ1 (ABC) transporter IX87_02470 ENOG4108ZX5 transcriptional regulator IX87_02480 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) IX87_02485 ENOG4105CK7 Sodium proline symporter IX87_02490 ENOG4105EW9 transcriptional regulator AsnC family IX87_02495 ENOG4105C26 Dehydrogenase IX87_02500 ENOG4105YGK Pfam:UPF0157 IX87_02515 ENOG4108T58 Mg2 transport protein CorA IX87_02525 ENOG4108YYC ycei family IX87_02535 ENOG4105CV1 Transketolase (EC 2.2.1.1) IX87_02560 ENOG4108HWY Beta-lactamase IX87_02585 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) IX87_02590 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) IX87_02610 ENOG4105X0I Fimbrial IX87_02625 ENOG4105GQR Chaperone IX87_02650 ENOG4108IPJ Membrane IX87_02660 ENOG4105ETS cytosine purines uracil thiamine allantoin IX87_02670 ENOG4105CC0 LysR family Transcriptional regulator IX87_02720 ENOG41067SE Tetr family transcriptional regulator IX87_02735 ENOG4105EW9 transcriptional regulator AsnC family IX87_02745 ENOG4105CDA abc transporter atp-binding protein IX87_02750 ENOG4105DRP amino acid AbC transporter IX87_02755 ENOG4105EAD ABC transporter IX87_02780 ENOG4107T8P acyl-Coa dehydrogenase IX87_02795 ENOG4105D01 (LipO)protein IX87_02800 ENOG4105D01 (LipO)protein IX87_02805 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) IX87_02810 ENOG4108UMI ABC transporter, permease IX87_02815 ENOG4105C3G gtp-binding protein IX87_02840 ENOG4108UMN azlc family IX87_02845 ENOG4105ZED uncharacterized protein ygaH IX87_02865 ENOG4105CHM Aminotransferase IX87_02875 ENOG4105E7U AraC family transcriptional regulator IX87_02880 ENOG4108V06 Glutathione peroxidase IX87_02890 ENOG4105CHM Aminotransferase IX87_02895 ENOG4105CK2 sodium dicarboxylate symporter IX87_02905 ENOG4105C0B DNA polymerase III (alpha subunit) IX87_02930 ENOG4108JU3 Alkyl hydroperoxide reductase IX87_02945 ENOG4108KB2 LysR family Transcriptional regulator IX87_02950 ENOG4105D6J arsenicaL-resistance protein IX87_02955 ENOG41082YX Transcriptional regulator, arsr family IX87_02970 ENOG4105CPN adenine deaminase IX87_02985 ENOG4105CBN LysR family transcriptional regulator IX87_02995 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease IX87_03005 ENOG4105E2B Taurine dioxygenase IX87_03010 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component IX87_03020 ENOG4106FTQ Taurine ABC transporter, periplasmic IX87_03040 ENOG4105C54 Major Facilitator superfamily IX87_03060 ENOG4105C4M (Ubiquinol oxidase) subunit I IX87_03065 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii IX87_03075 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IX87_03080 ENOG4108K70 Transcriptional regulator IX87_03100 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase IX87_03115 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) IX87_03120 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase IX87_03130 ENOG4105ETT transcriptional Regulator, LysR family IX87_03140 ENOG4105DXI Major Facilitator superfamily IX87_03160 ENOG41067MG lrgb family IX87_03165 ENOG4105VAW lrga family IX87_03170 ENOG4105CMU LysR family (Transcriptional regulator IX87_03175 ENOG4108SHQ Glutathione S-transferase IX87_03180 ENOG4105CYM Glutathione S-transferase IX87_03185 ENOG4105CBN LysR family transcriptional regulator IX87_03190 ENOG4105CHR reductase IX87_03220 ENOG4105D7W serine acetyltransferase IX87_03225 ENOG4105ESN nucleotide-binding protein IX87_03230 ENOG4105C9B Cysteine desulfurase IX87_03240 ENOG4105EXG Transcriptional regulator IX87_03245 ENOG4105CT1 (ABC) transporter IX87_03250 ENOG4107RP9 extracellular solute-binding protein, family 3 IX87_03255 ENOG4105CDA abc transporter atp-binding protein IX87_03260 ENOG4108HW4 amino acid AbC transporter IX87_03265 ENOG4105EAD ABC transporter IX87_03275 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase IX87_03280 ENOG4105BZU Histidine kinase IX87_03290 ENOG4105EW9 transcriptional regulator AsnC family IX87_03300 ENOG4105KT5 UmuD protein IX87_03320 ENOG4105CYX Short-chain dehydrogenase reductase Sdr IX87_03380 ENOG4105HEI LysR family (Transcriptional regulator IX87_03400 ENOG4105CEY Amp-dependent synthetase and ligase IX87_03405 ENOG4105R8C Transcriptional regulator IX87_03410 ENOG4105C1G acyl-Coa dehydrogenase IX87_03415 ENOG4107QX3 carboxylase IX87_03420 ENOG4105E39 Enoyl-CoA hydratase IX87_03435 ENOG4105CC0 LysR family Transcriptional regulator IX87_03450 ENOG4105CSU acyl-Coa dehydrogenase IX87_03460 ENOG4105EQ0 Major Facilitator superfamily IX87_03470 ENOG4107QNJ CoA-transferase subunit B IX87_03475 ENOG4107QP7 CoA-transferase subunit A IX87_03480 ENOG4107RGD Major Facilitator superfamily IX87_03485 ENOG4105C1G acyl-Coa dehydrogenase IX87_03490 ENOG4105E39 Enoyl-CoA hydratase IX87_03495 ENOG4105CHR reductase IX87_03500 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase IX87_03505 ENOG4105CHU acetyl-coa acetyltransferase IX87_03520 ENOG4105CCF Lysine exporter protein (Lyse ygga) IX87_03535 ENOG4105EA8 2-Nitropropane dioxygenase IX87_03540 ENOG4108UKI Enoyl-CoA hydratase IX87_03555 ENOG4105C1G acyl-Coa dehydrogenase IX87_03560 ENOG4107RGD Major Facilitator superfamily IX87_03565 ENOG4108KAZ Involved in phosphonate degradation (By similarity) IX87_03570 ENOG4107STF Involved in phosphonate degradation (By similarity) IX87_03580 ENOG4107RCV ABC transporter, permease IX87_03585 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) IX87_03590 ENOG4105C4Y ABC transporter IX87_03600 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase IX87_03605 ENOG4107HP6 Transcriptional regulator IX87_03615 ENOG4105HEI LysR family (Transcriptional regulator IX87_03620 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase IX87_03625 ENOG4105C26 Dehydrogenase IX87_03635 ENOG4105ETS cytosine purines uracil thiamine allantoin IX87_03645 ENOG4105C26 Dehydrogenase IX87_03650 ENOG4108M8W Monooxygenase IX87_03655 ENOG4105MXW flavin reductase domain protein, FMN-binding IX87_03660 ENOG4108MXF Alpha Beta Hydrolase IX87_03680 ENOG4105CPW cytochrome b561 IX87_03685 ENOG4107VGR Catalase IX87_03710 ENOG4107YAU phenylacetic acid degradation protein IX87_03720 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein IX87_03725 ENOG4105DZS Phenylacetate-CoA ligase IX87_03730 ENOG4105CHU acetyl-coa acetyltransferase IX87_03735 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase IX87_03740 ENOG4108UKI Enoyl-CoA hydratase IX87_03745 ENOG4105E39 Enoyl-CoA hydratase IX87_03750 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) IX87_03755 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit IX87_03760 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit IX87_03765 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit IX87_03770 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit IX87_03775 ENOG4105DXM phenylacetic acid degradation protein IX87_03780 ENOG4105EJQ L-serine dehydratase IX87_03785 ENOG4107QTZ amino acid IX87_03790 ENOG4105CZJ Aldehyde dehydrogenase IX87_03835 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) IX87_03850 ENOG4108Z4X TRANSCRIPTIONal IX87_03860 ENOG4105WPN DNA integration recombination invertion protein IX87_03875 ENOG4105DJ2 Major Facilitator Superfamily IX87_03880 ENOG4107Y2X deaminase IX87_03890 ENOG4105EMY transcriptional regulator IX87_03920 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit IX87_03930 ENOG4105UYK outer membrane protein a IX87_04000 ENOG4108HW3 (ABC) transporter IX87_04010 ENOG4105MRR Transcriptional regulator (By similarity) IX87_04035 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF IX87_04040 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase IX87_04055 ENOG4105E2A Dehydrogenase IX87_04090 ENOG4107R4J Chloride channel IX87_04095 ENOG4108JIK carboxylase IX87_04115 ENOG4105C5A transporter IX87_04125 ENOG4108WAV Transcriptional regulator IX87_04195 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) IX87_04220 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) IX87_04260 ENOG4105D2S major facilitator superfamily IX87_04270 ENOG4105D1S lipid A biosynthesis IX87_04275 ENOG4105BZU Histidine kinase IX87_04280 ENOG4107AQZ Membrane IX87_04305 ENOG4108Z4U Ferredoxin IX87_04345 ENOG4105DFG type I secretion outer membrane protein IX87_04350 ENOG4108IUZ ABC transporter IX87_04355 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA IX87_04365 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase IX87_04370 ENOG4105C2X Arabinose 5-phosphate isomerase IX87_04405 ENOG4107YPT transcriptional regulator IX87_04430 ENOG4105II7 pyrroline-5-carboxylate reductase IX87_04440 ENOG4105VEQ Cold shock protein IX87_04445 ENOG410829K Lysine exporter protein (Lyse ygga) IX87_04480 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) IX87_04540 ENOG4105EUV Phenol 2-monooxygenase IX87_04560 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein IX87_04570 ENOG4108KB2 LysR family Transcriptional regulator IX87_04575 ENOG4105FUY alpha subunit IX87_04580 ENOG4108UKV benzoate 1,2-dioxygenase IX87_04585 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein IX87_04590 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase IX87_04595 ENOG4105DKK Benzoate IX87_04600 ENOG4105D2S major facilitator superfamily IX87_04615 ENOG4105CQ7 ATP-dependent helicase IX87_04620 ENOG4105D3R alkyl hydroperoxide reductase IX87_04630 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) IX87_04640 ENOG4108JU3 Alkyl hydroperoxide reductase IX87_04650 ENOG4108K3A Glutathione S-transferase IX87_04660 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) IX87_04665 ENOG4108TGY Glutathione S-transferase IX87_04675 ENOG4108ZG0 Ompa motb domain protein IX87_04680 ENOG4105CD3 dihydroorotase IX87_04710 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit IX87_04725 ENOG4108UKZ OsmC family IX87_04730 ENOG4107RYR Transcriptional regulator, Crp Fnr family IX87_04735 ENOG4105CPC Aldo Keto reductase IX87_04750 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis IX87_04760 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase IX87_04770 ENOG4105DFP Integrase IX87_04830 ENOG4105E4C Lytic transglycosylase catalytic IX87_05125 ENOG4105CFH Aspartokinase IX87_05135 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) IX87_05145 ENOG4105CPW cytochrome b561 IX87_05150 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) IX87_05155 ENOG4105C7N Xanthine uracil vitamin C permease IX87_05165 ENOG4105F95 Monooxygenase IX87_05200 ENOG4105F95 Monooxygenase IX87_05205 ENOG4105JQZ Methyltransferase IX87_05215 ENOG4107RN6 Monooxygenase IX87_05240 ENOG4105D2S major facilitator superfamily IX87_05250 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) IX87_05255 ENOG4105E6M Sulphatase-modifying factor protein IX87_05270 ENOG4105E3J oxidoreductase IX87_05285 ENOG4108SC4 )-transporter IX87_05290 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase IX87_05305 ENOG4105C1G acyl-Coa dehydrogenase IX87_05310 ENOG4105EPF Outer membrane porin IX87_05315 ENOG4105NI3 Protein of unknown function (DUF3237) IX87_05345 ENOG4105CZJ Aldehyde dehydrogenase IX87_05350 ENOG4105JXH GntR family transcriptional regulator IX87_05370 ENOG4105DJB Major Facilitator Superfamily IX87_05375 ENOG4105CTX dehydratase IX87_05400 ENOG4108ZX5 transcriptional regulator IX87_05405 ENOG4107RGH Aldehyde dehydrogenase IX87_05410 ENOG4105C85 amino acid IX87_05440 ENOG4105C26 Dehydrogenase IX87_05465 ENOG4105CUB amino acid IX87_05475 ENOG4105C85 amino acid IX87_05525 ENOG4105CNA YD repeat protein IX87_05585 ENOG4105D01 (LipO)protein IX87_05595 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IX87_05630 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) IX87_05650 ENOG4108JQ5 ABC transporter IX87_05655 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component IX87_05660 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component IX87_05670 ENOG4105E9H Lytic Murein transglycosylase IX87_05670 ENOG4105E9H Lytic Murein transglycosylase IX87_05675 ENOG4107RZZ dna polymerase iii epsilon subunit IX87_05685 ENOG4105E09 nadh pyrophosphatase IX87_05695 ENOG4105W4M Transport-associated protein IX87_05705 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) IX87_05715 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) IX87_05720 ENOG4108ZUB Lysine exporter protein (Lyse ygga) IX87_05740 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family IX87_05745 ENOG4105D0A hydroxylase IX87_05750 ENOG4107RAQ aminopeptidase IX87_06065 ENOG4105CDU Replicative dna helicase IX87_06185 ENOG4105CBC glutamate synthase IX87_06215 ENOG4105C0A alcohol dehydrogenase IX87_06225 ENOG4105HSS phospholipase C IX87_06235 ENOG4107QMP dna polymerase iii subunits gamma and tau IX87_06260 ENOG4105CHR reductase IX87_06265 ENOG4105CHU acetyl-coa acetyltransferase IX87_06275 ENOG4105C5Q Transcriptional regulator IX87_06280 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) IX87_06285 ENOG4108NIW Leucine export protein LeuE IX87_06290 ENOG4105EW9 transcriptional regulator AsnC family IX87_06295 ENOG4105DKK Benzoate IX87_06305 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic IX87_06325 ENOG41081QV Universal stress protein IX87_06330 ENOG4105C5H ABC transporter IX87_06360 ENOG4105CNM Receptor IX87_06390 ENOG4105CUY Mechanosensitive ion channel IX87_06400 ENOG4105R8C Transcriptional regulator IX87_06420 ENOG4105EW9 transcriptional regulator AsnC family IX87_06425 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) IX87_06445 ENOG4105CD8 aminopeptidase N IX87_06470 ENOG4107QUV Domain protein IX87_06475 ENOG4105C0A alcohol dehydrogenase IX87_06485 ENOG4107RR1 TRANSCRIPTIONal IX87_06495 ENOG4107R55 ethanolamine transporter IX87_06500 ENOG4105CPD ethanolamine ammonia-lyase IX87_06505 ENOG4107FQ9 ethanolamine ammonia-lyase IX87_06510 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) IX87_06535 ENOG4108RCM Nitroreductase IX87_06540 ENOG4108TZV Membrane IX87_06545 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) IX87_06555 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) IX87_06560 ENOG4105K8N protein family UPF0079, ATPase IX87_06595 ENOG4105DZ2 Transcriptional regulator IX87_06610 ENOG4105F27 Major Facilitator IX87_06615 ENOG4105EYW Ion transport protein IX87_06625 ENOG4107QIJ Aconitate hydratase 2 IX87_06640 ENOG4105CFU surface antigen IX87_06645 ENOG4107S74 Lysophospholipid transporter LplT IX87_06670 ENOG4105CFQ glutamine synthetase IX87_06675 ENOG4105EEX Two component transcriptional regulator (Winged helix family IX87_06680 ENOG4105C08 Histidine kinase IX87_06690 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) IX87_06695 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) IX87_06715 ENOG4105D06 uba thif-type nad fad binding protein IX87_06720 ENOG4108MEJ flavin reductase domain protein IX87_06730 ENOG4105C1G acyl-Coa dehydrogenase IX87_06745 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) IX87_06760 ENOG4105CC0 LysR family Transcriptional regulator IX87_06775 ENOG4105DEN Luciferase family IX87_06785 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD IX87_06790 ENOG4105CND Glycosyl transferase, family 2 IX87_06795 ENOG4107BJW polysaccharide deacetylase IX87_06820 ENOG4105E2S oxidase) subunit II IX87_06825 ENOG4105BZ9 Cytochrome C oxidase, subunit I IX87_06830 ENOG4105CCU oxidase (Subunit III) IX87_06835 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) IX87_06860 ENOG4105CDU Replicative dna helicase IX87_06865 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) IX87_06920 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) IX87_06925 ENOG4105DC1 bifunctional purine biosynthesis protein purh IX87_06930 ENOG4105C12 Phosphoribosylglycinamide synthetase IX87_06940 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) IX87_06945 ENOG4108UMI ABC transporter, permease IX87_06950 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) IX87_06960 ENOG4105CK2 sodium dicarboxylate symporter IX87_07000 ENOG4105DY2 Paraquat-inducible protein b IX87_07005 ENOG4105F1S paraquat-inducible protein a IX87_07055 ENOG4105CSH Transporter IX87_07130 ENOG4105JXH GntR family transcriptional regulator IX87_07140 ENOG4105D6U Sodium Glutamate Symporter IX87_07170 ENOG4105H4F exported protein IX87_07205 ENOG4105C26 Dehydrogenase IX87_07210 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) IX87_07215 ENOG4105EVZ LysR family transcriptional regulator IX87_07290 ENOG4105D5K Hemolysin activator protein IX87_07315 ENOG4105D9P serine threonine protein kinase IX87_07340 ENOG4105VCC 30S ribosomal protein S21 IX87_07345 ENOG4105KTH gatB Yqey IX87_07350 ENOG4105ERG peptidase m48, ste24p IX87_07355 ENOG4105C5I Dehydrogenase IX87_07370 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase IX87_07405 ENOG41069NU Nitroreductase IX87_07415 ENOG4105C1J atp-dependent rna helicase IX87_07420 ENOG4105VEQ Cold shock protein IX87_07430 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) IX87_07435 ENOG4105M08 Membrane IX87_07465 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) IX87_07470 ENOG4105CIN aminoacyl-histidine dipeptidase IX87_07480 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase IX87_07485 ENOG4105CQC Prephenate dehydratase IX87_07490 ENOG4105NIV Esterase IX87_07495 ENOG4105C1G acyl-Coa dehydrogenase IX87_07500 ENOG4105CK2 sodium dicarboxylate symporter IX87_07505 ENOG4107QYG anthranilate phosphoribosyltransferase IX87_07510 ENOG4105VUT cytoplasmic protein IX87_07515 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) IX87_07520 ENOG4105BZ4 penicillin-binding protein IX87_07530 ENOG4105M6F mutator MutT protein IX87_07540 ENOG4105DHQ Histidine kinase IX87_07545 ENOG4105XJC Two component transcriptional regulator (Winged helix family IX87_07555 ENOG4107QHF type ii secretion system protein e IX87_07565 ENOG4108R96 Methyltransferase, YaeB family IX87_07570 ENOG4105DP0 ferredoxin-NADP reductase IX87_07575 ENOG4105JAB phenazine biosynthesis protein, phzf family IX87_07580 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IX87_07585 ENOG4105CFP Peptidase U32 IX87_07590 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding IX87_07600 ENOG4108JEH abc transporter atp-binding protein IX87_07605 ENOG4106YG3 ABC transporter IX87_07610 ENOG4105DSP amino acid AbC transporter IX87_07615 ENOG4105E89 ABC transporter IX87_07630 ENOG4105ENT Efflux transporter rnd family, mfp subunit IX87_07640 ENOG4105ENJ RND efflux system, outer membrane lipoprotein IX87_07845 ENOG4108XTP Transcriptional regulator IX87_07925 ENOG4105DA5 (ABC) transporter IX87_07930 ENOG4105E3A (ABC) transporter IX87_07945 ENOG4105CNI cell division protein FtsW IX87_07950 ENOG4105CVE Lytic murein transglycosylase IX87_07990 ENOG4105CE9 30S ribosomal protein S2 IX87_07995 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) IX87_08005 ENOG4107RNU major facilitator superfamily MFS_1 IX87_08020 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) IX87_08025 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) IX87_08030 ENOG4107QPN acyl-Coa dehydrogenase IX87_08045 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) IX87_08050 ENOG4105SYT Methylenetetrahydrofolate reductase IX87_08055 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) IX87_08065 ENOG4105C6K Malic enzyme IX87_08075 ENOG4105C0H protease IX87_08080 ENOG4107QNR UPF0135 protein IX87_08085 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) IX87_08120 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) IX87_08130 ENOG4105C5F glutamine synthetase IX87_08135 ENOG4105DUX Transporter IX87_08145 ENOG4105DFP Integrase IX87_08440 ENOG41067QW Transcriptional regulator IX87_08525 ENOG4105DDQ anthranilate synthase IX87_08560 ENOG4105C7W Xanthine dehydrogenase IX87_08570 ENOG4105EUJ GTP cyclohydrolase i IX87_08600 ENOG4105NX3 Membrane IX87_08615 ENOG4105E4F Isochorismate synthase IX87_08630 ENOG4108JJ7 ABC transporter IX87_08635 ENOG4105BZ1 (ABC) transporter IX87_08650 ENOG4105WQI isochorismatase IX87_08655 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase IX87_08660 ENOG4105C0W non-ribosomal peptide synthetase IX87_08680 ENOG4108IPW abc transporter atp-binding protein IX87_08695 ENOG4105CEY Amp-dependent synthetase and ligase IX87_08710 ENOG4105WWK YheO domain protein IX87_08720 ENOG4105C2I pirin domain protein IX87_08760 ENOG4105VCD cytoplasmic protein IX87_08765 ENOG4105D22 carbon starvation protein IX87_08775 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein IX87_08785 ENOG41066DG (EAL) domain protein IX87_08795 ENOG4105DHU Bile acid IX87_08805 ENOG4105EYM Major Facilitator superfamily IX87_08810 ENOG4105DAN ATP-dependent protease IX87_08815 ENOG4105EJC lysr family transcriptional regulator IX87_08820 ENOG4108K5P (LipO)protein IX87_08840 ENOG4105DZ1 carboxypeptidase IX87_08845 ENOG4108Z0R Transferase IX87_08865 ENOG4107QTF adenylosuccinate lyase IX87_08880 ENOG4105ERU peptidase IX87_08885 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) IX87_08895 ENOG4105C8U phosphate abc transporter IX87_08900 ENOG4105CVA phosphate IX87_08905 ENOG4105C85 amino acid IX87_08910 ENOG4107RA9 decarboxylase IX87_08915 ENOG4105F7P transcriptional regulator AsnC family IX87_08925 ENOG4105DY8 decarboxylase IX87_08930 ENOG4108JPW Aminotransferase IX87_08955 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) IX87_08970 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) IX87_08975 ENOG4105D3G Pseudouridine synthase IX87_08990 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) IX87_09020 ENOG4105JAB phenazine biosynthesis protein, phzf family IX87_09025 ENOG4108ETY sodium dicarboxylate symporter IX87_09030 ENOG4105EGI Transcriptional regulator IX87_09035 ENOG4105CBP Major Facilitator IX87_09055 ENOG4108R99 pseudouridine synthase IX87_09060 ENOG4105E9K Isocitrate dehydrogenase IX87_09070 ENOG4105DZ1 carboxypeptidase IX87_09075 ENOG4105CEP NADH dehydrogenase IX87_09080 ENOG4108YZY peptidylprolyl cis-trans isomerase IX87_09085 ENOG4105CVP deoxyribo-dipyrimidine photolyase IX87_09100 ENOG4107R8N Glycosyl transferase, family 2 IX87_09130 ENOG4105EA8 2-Nitropropane dioxygenase IX87_09135 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) IX87_09140 ENOG4107QS8 (LipO)protein IX87_09175 ENOG4105DTR rard protein IX87_09195 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) IX87_09205 ENOG4105BZU Histidine kinase IX87_09240 ENOG4105EMU Dehydrogenase IX87_09245 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase IX87_09250 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) IX87_09255 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) IX87_09265 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) IX87_09280 ENOG4105C3F Signal peptidase i IX87_09295 ENOG4105C0H protease IX87_09300 ENOG4108IYU L-aspartate oxidase IX87_09315 ENOG4105HHA aminodeoxychorismate lyase IX87_09320 ENOG4105YAZ 4-amino-4-deoxychorismate lyase IX87_09325 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein IX87_09335 ENOG4108I5D sulfate abc transporter IX87_09345 ENOG4108IJ6 ABC transporter IX87_09350 ENOG4107R11 Transcriptional regulator IX87_09365 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) IX87_09370 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) IX87_09385 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen IX87_09415 ENOG4105C2C drug resistance transporter, Bcr CflA IX87_09420 ENOG4108ETH Formylglycinamide ribotide synthetase IX87_09440 ENOG4105CH2 amidohydrolase IX87_09445 ENOG4107YD3 Thioesterase IX87_09450 ENOG4105E02 MotA TolQ exbB proton channel IX87_09455 ENOG4105M8F Biopolymer transport protein exbD tolR IX87_09465 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) IX87_09470 ENOG4105KCK Peptidoglycan-associated lipoprotein IX87_09530 ENOG4105C02 permease IX87_09540 ENOG4108V3E phosphoribosylglycinamide formyltransferase IX87_09545 ENOG4107R6F Alpha Beta Hydrolase Fold protein IX87_09550 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) IX87_09560 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 IX87_09565 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) IX87_09570 ENOG4105D60 lipoprotein releasing system transmembrane protein IX87_09600 ENOG4107KET secretion protein, HlyD family IX87_09635 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) IX87_09640 ENOG4105C10 Electron transfer flavoprotein IX87_09645 ENOG4105BZJ Electron transfer flavoprotein IX87_09650 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) IX87_09655 ENOG4105N14 lysine exporter protein LysE YggA IX87_09665 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) IX87_09675 ENOG4105C85 amino acid IX87_09680 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) IX87_09690 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) IX87_09705 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) IX87_09710 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit IX87_09715 ENOG4105BZW Glycerate kinase IX87_09780 ENOG4105YCT UPF0386 protein IX87_09790 ENOG4105CEY Amp-dependent synthetase and ligase IX87_09805 ENOG4108RRZ Transcription elongation factor GreB IX87_09825 ENOG4105E4C Lytic transglycosylase catalytic IX87_09840 ENOG4105BZS acriflavin resistance protein IX87_09845 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase IX87_09855 ENOG41080IJ Diacylglycerol kinase IX87_09875 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) IX87_09890 ENOG4105C6V Glycerol-3-phosphate dehydrogenase IX87_09895 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) IX87_09900 ENOG4105CSH Transporter IX87_09955 ENOG4105EEI dihydropteroate synthase IX87_09960 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) IX87_09970 ENOG4105HBR Rna-binding protein IX87_09985 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain IX87_09990 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain IX87_10005 ENOG41080TK Universal stress protein IX87_10020 ENOG4105PNM synthesis protein IX87_10060 ENOG4105EEQ Na H antiporter IX87_10065 ENOG4105CGZ zinc metallopeptidase IX87_10070 ENOG4105CKW Inner membrane protein yedI IX87_10080 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha IX87_10090 ENOG4107QN2 dihydrolipoyl dehydrogenase IX87_10095 ENOG4105C7S Dehydrogenase IX87_10100 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 IX87_10105 ENOG4105E33 succinate dehydrogenase IX87_10115 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein IX87_10120 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit IX87_10155 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) IX87_10160 ENOG41084BA UPF0250 protein IX87_10165 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) IX87_10180 ENOG4105CUB amino acid IX87_10190 ENOG4105KVH Transcriptional regulator IX87_10195 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) IX87_10200 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) IX87_10215 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) IX87_10245 ENOG4105C8N cysteinyl-tRNA synthetase IX87_10250 ENOG410841Q phosphoesterase PA-phosphatase related protein IX87_10255 ENOG4105C1P efflux transporter, rnd family, mfp subunit IX87_10260 ENOG4105BZS acriflavin resistance protein IX87_10265 ENOG4105ENJ RND efflux system, outer membrane lipoprotein IX87_10270 ENOG4105K8R UPF0145 protein IX87_10275 ENOG4105K8R UPF0145 protein IX87_10295 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) IX87_10315 ENOG4108M0I Transcriptional regulator IX87_10330 ENOG4105DHQ Histidine kinase IX87_10335 ENOG4105XJC Two component transcriptional regulator (Winged helix family IX87_10340 ENOG4105DIJ Phosphoethanolamine transferase IX87_10365 ENOG4105D78 K07001 NTE family protein IX87_10380 ENOG4105MSB protein, conserved in bacteria IX87_10385 ENOG4105CTB Polyprenyl synthetase IX87_10390 ENOG4105C7F AcnD-accessory protein PrpF IX87_10395 ENOG4105C85 amino acid IX87_10590 ENOG4105CDU Replicative dna helicase IX87_10615 ENOG41067QW Transcriptional regulator IX87_10675 ENOG4105CF7 AraC family transcriptional regulator IX87_10705 ENOG4108X0B nad(p)h dehydrogenase (quinone) IX87_10715 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein IX87_10725 ENOG4105D8T Acyltransferase IX87_10735 ENOG4105C03 ribonuclease IX87_10740 ENOG4108Z03 MAF-like protein IX87_10745 ENOG4105VQ7 Rod shape-determining protein MreD IX87_10750 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) IX87_10755 ENOG4105DFF Rod shape-determining protein mreb IX87_10760 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) IX87_10770 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) IX87_10820 ENOG4105C7B Threonine dehydratase IX87_10825 ENOG4105D78 K07001 NTE family protein IX87_10830 ENOG4105BZG amino acid carrier protein IX87_10850 ENOG4105C2C drug resistance transporter, Bcr CflA IX87_10855 ENOG4105EM2 membrane IX87_10865 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) IX87_10905 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein IX87_10910 ENOG4105WD1 Membrane IX87_10920 ENOG4106HKS Entericidin EcnA/B family IX87_10935 ENOG4105CBS Chea signal transduction histidine kinase IX87_10940 ENOG4105C8Q Methyl-accepting chemotaxis IX87_10945 ENOG4108ZGA chew protein IX87_10950 ENOG4105M3Z response regulator IX87_10955 ENOG4108UNF response regulator IX87_10980 ENOG4105KWI UPF0339 protein IX87_10985 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA IX87_10990 ENOG4105K78 MarR family Transcriptional regulator IX87_11000 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) IX87_11005 ENOG4105T95 Thiol disulfide interChange protein IX87_11015 ENOG4108N2Y auxin Efflux IX87_11020 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IX87_11025 ENOG4105CHB tonB-dependent Receptor IX87_11030 ENOG4108VX5 3-methyladenine DNA glycosylase IX87_11040 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) IX87_11060 ENOG4105C2W permease IX87_11070 ENOG4108IQI permease IX87_11075 ENOG4105E0Y RtcB Protein IX87_11085 ENOG4108WHA ompa motb domain protein IX87_11095 ENOG4105CHU acetyl-coa acetyltransferase IX87_11105 ENOG410814C multidrug resistance protein IX87_11115 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) IX87_11120 ENOG4105DZG Dehydrogenase IX87_11125 ENOG4105TW1 Carbohydrate-selective porin OprB IX87_11135 ENOG4108R6W Transcriptional regulator, ARAC family IX87_11140 ENOG4105CHU acetyl-coa acetyltransferase IX87_11185 ENOG4108UT2 hemolysin iii IX87_11190 ENOG4105CSH Transporter IX87_11205 ENOG4105D3R alkyl hydroperoxide reductase IX87_11225 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase IX87_11260 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) IX87_11275 ENOG4108WBT adenosyltransferase IX87_11295 ENOG4105CNG UPF0061 protein IX87_11300 ENOG4105E3W Two component transcriptional regulator (Winged helix family IX87_11305 ENOG4105EB3 Histidine kinase IX87_11315 ENOG4105CSU acyl-Coa dehydrogenase IX87_11320 ENOG4105CSU acyl-Coa dehydrogenase IX87_11325 ENOG4108VY7 phosphate-starvation-inducible protein PsiE IX87_11345 ENOG4105UGU tonB-dependent Receptor IX87_11405 ENOG4108PQP glycosyl transferase group 1 IX87_11415 ENOG4107BJW polysaccharide deacetylase IX87_11430 ENOG4105CM2 brancheD-chain amino acid aminotransferase IX87_11435 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) IX87_11440 ENOG4105BZU Histidine kinase IX87_11505 ENOG4105VIE preprotein translocase, subunit YajC IX87_11510 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) IX87_11515 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) IX87_11520 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase IX87_11530 ENOG4105FFC UPF0187 protein IX87_11535 ENOG4105DB7 PHP domain protein IX87_11545 ENOG4105K9H YciI-like protein IX87_11575 ENOG4105NAU thioesterase Superfamily protein IX87_11585 ENOG4107U2T alpha beta IX87_11590 ENOG4107QPB Beta-lactamase domain protein IX87_11600 ENOG4107QN2 dihydrolipoyl dehydrogenase IX87_11635 ENOG4108KHX Diguanylate cyclase IX87_11640 ENOG4105UYK outer membrane protein a IX87_11650 ENOG4107RZC phospholipase d IX87_11660 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) IX87_11680 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) IX87_11685 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) IX87_11690 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) IX87_11700 ENOG4108UJD 30S ribosomal protein S9 IX87_11705 ENOG4107MKT Stringent starvation protein a IX87_11710 ENOG4105KB2 stringent starvation protein b IX87_11730 ENOG4105C1G acyl-Coa dehydrogenase IX87_11735 ENOG4107QX3 carboxylase IX87_11750 ENOG4108RZE Tetr family transcriptional regulator IX87_11755 ENOG4105C1G acyl-Coa dehydrogenase IX87_11800 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase IX87_11805 ENOG4105D6S protein involved in catabolism of external DNA IX87_11835 ENOG4105E4C Lytic transglycosylase catalytic IX87_11845 ENOG4105C9A Phoh family IX87_11875 ENOG4105CS1 NAD(P)H quinone oxidoreductase IX87_11880 ENOG4107S2Z UPF0761 membrane protein IX87_11895 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase IX87_11945 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) IX87_11950 ENOG4105DGW oligopeptidase A IX87_11955 ENOG4105VKU nucleicacid-binding protein IX87_11995 ENOG4105C1G acyl-Coa dehydrogenase IX87_12020 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) IX87_12030 ENOG41067V7 50S ribosomal protein L36 IX87_12035 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) IX87_12145 ENOG41089BK Glutamine amido-transferase IX87_12150 ENOG4105C28 cystathionine IX87_12155 ENOG4105D7A ATP-binding protein IX87_12165 ENOG4105KPV Transcriptional regulator IX87_12180 ENOG4105CK2 sodium dicarboxylate symporter IX87_12185 ENOG4105C29 acyl-CoA thioesterase IX87_12205 ENOG4105CB5 ATP-dependent DNA helicase recG IX87_12210 ENOG4105MJ2 Competence protein IX87_12220 ENOG4108URH decarboxylase IX87_12225 ENOG4105D7N magnesium and cobalt transport protein CorA IX87_12235 ENOG4105E3I toluene tolerance IX87_12245 ENOG4105CY3 ABC transporter, permease IX87_12250 ENOG4105DHJ ABC, transporter IX87_12260 ENOG4105C1J atp-dependent rna helicase IX87_12265 ENOG4105ECY inositol monophosphatase IX87_12280 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) IX87_12305 ENOG4105CSU acyl-Coa dehydrogenase IX87_12315 ENOG41067S9 phage shock protein C, PspC IX87_12320 ENOG4105W87 Cbs domain IX87_12355 ENOG41090JH (ATPase)-like protein IX87_12375 ENOG4105EGI Transcriptional regulator IX87_12390 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin IX87_12415 ENOG4105C26 Dehydrogenase IX87_12425 ENOG4105C8Y Acetylornithine aminotransferase IX87_12430 ENOG4105D82 Glutamate dehydrogenase IX87_12435 ENOG4108IQI permease IX87_12475 ENOG4107SKI cobyrinic Acid a,c-diamide synthase IX87_12480 ENOG4105IPI Membrane IX87_12485 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) IX87_12490 ENOG4105EM2 membrane IX87_12505 ENOG4105NF4 modulator of drug activity IX87_12510 ENOG4105VRH Antibiotic biosynthesis monooxygenase IX87_12535 ENOG4105CQB FAD linked oxidase domain protein IX87_12540 ENOG4108JQ1 Dehydrogenase IX87_12565 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) IX87_12570 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) IX87_12575 ENOG4107IFA Lipase (EC 3.1.1.3) IX87_12590 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) IX87_12640 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) IX87_12650 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) IX87_12655 ENOG4105KME endoribonuclease L-psp IX87_12665 ENOG4108UQY Iron-storage protein IX87_12670 ENOG4108YSG O-Antigen polymerase IX87_12690 ENOG4105HA9 of methanol dehydrogenase type IX87_12695 ENOG4108V0P LemA family IX87_12705 ENOG4105BZ8 glutamate synthase IX87_12710 ENOG4105CBC glutamate synthase IX87_12790 ENOG4105E4G Type IV pilus IX87_12815 ENOG4108JQC penicillin-binding protein 1A IX87_12820 ENOG4105DHI Methyltransferase IX87_12835 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) IX87_12840 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) IX87_12845 ENOG4105CJN penicillin-binding protein IX87_12860 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein IX87_12890 ENOG4108IQI permease IX87_12985 ENOG4105C5H ABC transporter IX87_12995 ENOG4105PDP Short chain dehydrogenase IX87_13000 ENOG4105CHH sulfate transporter IX87_13010 ENOG4105DPZ Two component transcriptional regulator (Winged helix family IX87_13015 ENOG4105E0F Histidine kinase IX87_13020 ENOG4105CYC Transferase IX87_13050 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) IX87_13080 ENOG41061CK Antibiotic biosynthesis monooxygenase IX87_13095 ENOG4105CUV Homoserine Kinase IX87_13170 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) IX87_13230 ENOG4108R0M Aminoglycoside IX87_13250 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein IX87_13255 ENOG4105KVH Transcriptional regulator IX87_13285 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) IX87_13290 ENOG4105CPC Aldo Keto reductase IX87_13310 ENOG4106NZI LysR family Transcriptional regulator IX87_13315 ENOG4105D94 Major Facilitator Superfamily IX87_13325 ENOG4105C85 amino acid IX87_13330 ENOG4105C26 Dehydrogenase IX87_13345 ENOG4108K8K Transcriptional regulator IX87_13390 ENOG4105EUB pirin domain protein IX87_13395 ENOG4105CHJ isochorismatase hydrolase IX87_13405 ENOG4105C26 Dehydrogenase IX87_13410 ENOG4108JPW Aminotransferase IX87_13420 ENOG4105C85 amino acid IX87_13430 ENOG4108UMN azlc family IX87_13440 ENOG4108UUM single-stranded DNA-binding protein IX87_13445 ENOG4107RDB Major Facilitator IX87_13455 ENOG4105DWF phosphomethylpyrimidine kinase IX87_13460 ENOG4105RA2 Membrane IX87_13470 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein IX87_13475 ENOG4108WUH Transcriptional regulator, TetR family IX87_13480 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) IX87_13485 ENOG4105BZU Histidine kinase IX87_13495 ENOG4105C94 Transporter IX87_13515 ENOG4107QN1 sodium solute IX87_13520 ENOG41062QD Membrane IX87_13525 ENOG4105BZU Histidine kinase IX87_13540 ENOG4108UZX fmn reductase IX87_13545 ENOG4105FBW Monooxygenase IX87_13555 ENOG4108W2Y isochorismatase IX87_13560 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) IX87_13570 ENOG4105D64 Mechanosensitive ion channel IX87_13580 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase IX87_13585 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IX87_13595 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) IX87_13605 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) IX87_13620 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) IX87_13645 ENOG4105E0K tonB-dependent siderophore receptor IX87_13660 ENOG4107QSN dihydrolipoamide acetyltransferase IX87_13665 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) IX87_13670 ENOG41063SB peptidase IX87_13685 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) IX87_13690 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) IX87_13695 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) IX87_13715 ENOG4105D7Z glutathione synthase IX87_13740 ENOG4107RRE RNA-directed DNA polymerase IX87_13745 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) IX87_13760 ENOG4105CGK Exodeoxyribonuclease III IX87_13765 ENOG4105KUZ arsenate reductase IX87_13780 ENOG4105BZU Histidine kinase IX87_13785 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) IX87_13815 ENOG41084YZ Hydrolase IX87_13830 ENOG41061H0 Monooxygenase IX87_13840 ENOG4108Z2U ureidoglycolate hydrolase IX87_13845 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) IX87_13850 ENOG4105IPS esterase IX87_13890 ENOG4105CS6 Rhs element vgr protein IX87_13900 ENOG4105D9M gamma-glutamylcysteine synthetase IX87_13915 ENOG4106BRA Membrane IX87_13920 ENOG4105CHM Aminotransferase IX87_13925 ENOG4107QJQ Mate efflux family protein IX87_13940 ENOG4105CK6 Two component transcriptional regulator (Winged helix family IX87_13945 ENOG4105BZU Histidine kinase IX87_13960 ENOG4105KHC sulfurtransferase IX87_13995 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) IX87_14010 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) IX87_14015 ENOG4108ZAI phosphatidylglycerophosphatase a IX87_14025 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) IX87_14030 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) IX87_14045 ENOG41088SP formiminoglutamate hydrolase IX87_14055 ENOG4105C85 amino acid IX87_14070 ENOG41090B9 response to stress IX87_14075 ENOG4105CZE histidine utilization repressor IX87_14085 ENOG4105CKI cobalamin synthesis protein IX87_14095 ENOG4105C85 amino acid IX87_14105 ENOG4108RXX maleylacetoacetate isomerase IX87_14125 ENOG4105EWC Purine nucleoside phosphorylase IX87_14130 ENOG4105UQX Mate efflux family protein IX87_14135 ENOG4105C09 Bile acid IX87_14140 ENOG4108RWI nicotinamidase IX87_14145 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) IX87_14165 ENOG4105S64 Formate nitrite transporter IX87_14170 ENOG4105D1H recombination factor protein RarA IX87_14180 ENOG4108ZZ3 UPF0260 protein IX87_14200 ENOG4105CEN a g-specific adenine glycosylase IX87_14215 ENOG4108R3E Dna-3-methyladenine glycosylase i IX87_14220 ENOG4105DQ4 alcohol dehydrogenase IX87_14235 ENOG4105HEI LysR family (Transcriptional regulator IX87_14240 ENOG4105CV8 reductase IX87_14245 ENOG4105F27 Major Facilitator IX87_14280 ENOG4105DJY efflux transporter, rnd family, mfp subunit IX87_14285 ENOG4108IG5 Transcriptional regulator IX87_14295 ENOG4105C2W permease IX87_14300 ENOG4108W5M transcriptional regulator IX87_14325 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B IX87_14335 ENOG4105C8J )-transporter IX87_14380 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) IX87_14385 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) IX87_14390 ENOG4105D74 hydrolase IX87_14400 ENOG4108821 RND type efflux pump IX87_14405 ENOG4108821 RND type efflux pump IX87_14410 ENOG4108821 RND type efflux pump IX87_14415 ENOG4105C5H ABC transporter IX87_14420 ENOG4105DQR SNARE associated Golgi IX87_14430 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) IX87_14440 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) IX87_14450 ENOG4105VG0 50S ribosomal protein l34 IX87_14465 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins IX87_14480 ENOG4105PGM cation diffusion facilitator family transporter IX87_14485 ENOG4105T95 Thiol disulfide interChange protein IX87_14505 ENOG4108UGV hypoxanthine phosphoribosyltransferase IX87_14515 ENOG4107QUY Guanine deaminase IX87_14525 ENOG4106032 Glutathionylspermidine synthase IX87_14535 ENOG4105DU1 integral membrane protein, terc IX87_14540 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase IX87_14550 ENOG4105DFU Cell wall formation (By similarity) IX87_14565 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) IX87_14570 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit IX87_14575 ENOG4105CVE Lytic murein transglycosylase IX87_14635 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) IX87_14675 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase IX87_14685 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) IX87_14690 ENOG4105DTN riboflavin biosynthesis protein ribF IX87_14700 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) IX87_14705 ENOG4108R86 Transcriptional regulator IX87_14710 ENOG4108VM9 ABC, transporter IX87_14715 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component IX87_14720 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) IX87_14725 ENOG4105GVF (ABC) transporter IX87_14730 ENOG4105GVF (ABC) transporter IX87_14735 ENOG4107QZM n-acetylglutamate synthase IX87_14750 ENOG4105UBK short-chain dehydrogenase reductase IX87_14755 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) IX87_14770 ENOG41062JF Transcriptional regulator IX87_14800 ENOG4105HSS phospholipase C IX87_14810 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase IX87_14815 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase IX87_14820 ENOG4105CJR Integral membrane protein (MviN IX87_14825 ENOG4108V1T peptidylprolyl cis-trans isomerase IX87_14830 ENOG4108V1T peptidylprolyl cis-trans isomerase IX87_14835 ENOG4105D75 Capsular exopolysaccharide family IX87_14845 ENOG4105DAY polysaccharide export protein IX87_14850 ENOG4107QQG Dehydrogenase IX87_14890 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase IX87_14905 ENOG4107UKG Glycosyl transferase, family 4 IX87_14920 ENOG4105D3Q Sugar transferase IX87_14925 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase IX87_14930 ENOG4105C6Y Udp-glucose 6-dehydrogenase IX87_14940 ENOG4105CMR udp-glucose 4-epimerase IX87_14945 ENOG4107QKV phosphomannomutase IX87_14950 ENOG4105DAA L-lactate IX87_14955 ENOG41073TP transcriptional regulator IX87_14965 ENOG4105CXG d-lactate dehydrogenase IX87_14970 ENOG4105CGF Aromatic amino acid aminotransferase IX87_14975 ENOG4105DRR Transcriptional regulator, GntR family IX87_14980 ENOG4105CR4 methylisocitrate lyase IX87_14985 ENOG4105BZN citrate synthase IX87_14990 ENOG4108I0Z Aconitate hydratase IX87_15005 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) IX87_15035 ENOG4105D3G Pseudouridine synthase IX87_15060 ENOG4105EW9 transcriptional regulator AsnC family IX87_15075 ENOG4105M4H endoribonuclease L-psp IX87_15080 ENOG4105C85 amino acid IX87_15085 ENOG4105C85 amino acid IX87_15095 ENOG4105C26 Dehydrogenase IX87_15100 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase IX87_15110 ENOG4105C1G acyl-Coa dehydrogenase IX87_15115 ENOG4105E39 Enoyl-CoA hydratase IX87_15120 ENOG4105E39 Enoyl-CoA hydratase IX87_15125 ENOG4105CSH Transporter IX87_15160 ENOG4105C1G acyl-Coa dehydrogenase IX87_15205 ENOG4107PSF BolA-like protein IX87_15215 ENOG4107QJE Chromosome Partitioning Protein IX87_15230 ENOG4105DQR SNARE associated Golgi IX87_15235 ENOG4108VBZ doxx family IX87_15240 ENOG4106MP8 UPF0754 membrane protein IX87_15245 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) IX87_15265 ENOG4105EUB pirin domain protein IX87_15290 ENOG4107R1I NAD-dependent malic enzyme IX87_15295 ENOG4105EZR dyp-type peroxidase family protein IX87_15305 ENOG4105FAV ABC, transporter IX87_15310 ENOG4105FDK ABC transporter IX87_15335 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) IX87_15375 ENOG4108V06 Glutathione peroxidase IX87_15385 ENOG4107RTG Major Facilitator superfamily IX87_15390 ENOG4108IND Tetr family transcriptional regulator IX87_15405 ENOG4105C79 DNA protecting protein DprA IX87_15440 ENOG4105Y7M Transcriptional regulator, TetR family IX87_15475 ENOG4105C6T cysteine synthase IX87_15485 ENOG4105CS1 NAD(P)H quinone oxidoreductase IX87_15505 ENOG4105CCT upf0313 protein IX87_15520 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) IX87_15530 ENOG4105C0R drug resistance transporter emrb qaca subfamily IX87_15545 ENOG4108URH decarboxylase IX87_15550 ENOG4105EE5 Membrane protein terC IX87_15555 ENOG4105K5B UPF0225 protein IX87_15560 ENOG4105EN6 Membrane IX87_15565 ENOG41079KZ Major Facilitator Superfamily IX87_15570 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) IX87_15575 ENOG4105CEY Amp-dependent synthetase and ligase IX87_15590 ENOG4105F0N pyrophosphate phospho-hydrolase IX87_15595 ENOG4105EPF Outer membrane porin IX87_15615 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) IX87_15625 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IX87_15630 ENOG4105C0P Mg chelatase subunit ChlI IX87_15645 ENOG4105BZU Histidine kinase IX87_15655 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) IX87_15695 ENOG4108K5H permease YjgP YjgQ family protein IX87_15700 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) IX87_15705 ENOG4105CN1 protease IX87_15710 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family IX87_15730 ENOG4107TUY Histidine kinase IX87_15740 ENOG41061WM D-Alanyl-D-Alanine IX87_15750 ENOG4105D6E homoserine dehydrogenase IX87_15755 ENOG4105T95 Thiol disulfide interChange protein IX87_15760 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) IX87_15770 ENOG4105CE1 Ferrous iron transport protein b IX87_15785 ENOG4105CNI cell division protein FtsW IX87_15790 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) IX87_15795 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters IX87_15800 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) IX87_15825 ENOG4108RNG Permease of the drug metabolite transporter IX87_15830 ENOG4105DFG type I secretion outer membrane protein IX87_15835 ENOG4108UTW Plays a role in the regulation of phosphate uptake IX87_15850 ENOG4108HRK Histidine kinase IX87_15855 ENOG4108NEV two component transcriptional regulator, LytTR family IX87_15860 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) IX87_15885 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS IX87_15900 ENOG4105GVR general secretion pathway protein D IX87_15905 ENOG4105TV9 FHA Domain-Containing protein IX87_15910 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) IX87_15955 ENOG4105PM1 preprotein translocase subunit SecE IX87_15960 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) IX87_16010 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) IX87_16015 ENOG4105D3Y Na H antiporter IX87_16030 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) IX87_16045 ENOG4107ZXU DSBA oxidoreductase IX87_16120 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase IX87_16125 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) IX87_16155 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) IX87_16165 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) IX87_16180 ENOG4105C2N RNA methyltransferase TrmH family group 3 IX87_16190 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) IX87_16205 ENOG4107QHF type ii secretion system protein e IX87_16215 ENOG4107EJC Preprotein translocase subunit SecG IX87_16245 ENOG4105CHV Transcription elongation factor NusA IX87_16260 ENOG4105KJM monovalent cation h antiporter subunit g IX87_16265 ENOG4105W4C monovalent cation H antiporter subunit F IX87_16270 ENOG4105SC1 monovalent cation H antiporter subunit E IX87_16275 ENOG4107R4Z monovalent cation h antiporter subunit d IX87_16280 ENOG4108ZE9 Monovalent cation H antiporter subunit C IX87_16285 ENOG4105D65 subunit l IX87_16300 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase IX87_16310 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) IX87_16320 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) IX87_16330 ENOG4105CSR polyphosphate kinase 2 IX87_16340 ENOG4105DSY exodeoxyribonuclease V, gamma IX87_16345 ENOG4107QKA exodeoxyribonuclease V beta IX87_16350 ENOG4107QYX exodeoxyribonuclease v alpha IX87_16370 ENOG4107QUT magnesium and cobalt transport protein CorA IX87_16375 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) IX87_16380 ENOG4105DVC DnaJ domain protein IX87_16395 ENOG4105CKD glutathione-regulated potassium-efflux system protein IX87_16400 ENOG4105C25 Primosomal protein n' IX87_16405 ENOG4105D7Q type ii secretion system IX87_16410 ENOG4108VAU general secretion pathway protein G IX87_16420 ENOG4108Z7R Chaperone CsaA IX87_16425 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) IX87_16430 ENOG4108JU5 Magnesium and cobalt efflux protein IX87_16435 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) IX87_16440 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase IX87_16450 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) IX87_16465 ENOG4105C5X domain protein IX87_16470 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) IX87_16480 ENOG4105BZ8 glutamate synthase IX87_16510 ENOG4107T8P acyl-Coa dehydrogenase IX87_16520 ENOG4107QI1 Mate efflux family protein IX87_16530 ENOG4105CSA Coproporphyrinogen iii oxidase IX87_16540 ENOG4105CBN LysR family transcriptional regulator IX87_16560 ENOG4105C03 ribonuclease IX87_16565 ENOG4105EI2 Pseudouridine synthase IX87_16570 ENOG4107XGZ Hydrolase IX87_16575 ENOG4105D29 Helix-turn-helix type 11 domain protein IX87_16610 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase IX87_16635 ENOG4105DUM transcriptional regulator, lysR family IX87_16660 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) IX87_16715 ENOG4105CK2 sodium dicarboxylate symporter IX87_16725 ENOG4105D1S lipid A biosynthesis IX87_16730 ENOG4105N14 lysine exporter protein LysE YggA IX87_16735 ENOG4105C5H ABC transporter IX87_16740 ENOG41069P5 Protein slyX homolog IX87_16750 ENOG4105KVH Transcriptional regulator IX87_16760 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) IX87_16775 ENOG4105C4R Atp-dependent dna helicase IX87_16780 ENOG4105VFU Rna-binding protein IX87_16800 ENOG4105CKD glutathione-regulated potassium-efflux system protein IX87_16805 ENOG4105W0E 50S ribosomal protein L33 IX87_16810 ENOG4105KDC 50s ribosomal protein l28 IX87_16825 ENOG4108HWY Beta-lactamase IX87_16845 ENOG4107RGH Aldehyde dehydrogenase IX87_16855 ENOG4105CIY formyltetrahydrofolate deformylase IX87_16955 ENOG4105DWV Homoserine O-trans-acetylase IX87_16965 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) IX87_16975 ENOG4108ESX Receptor IX87_16985 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) IX87_17005 ENOG4107GFK fumarate IX87_17010 ENOG4108DNC Involved in acetate metabolism (By similarity) IX87_17015 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) IX87_17025 ENOG4105C01 Dihydroxy-acid dehydratase IX87_17030 ENOG4108UHU Aldolase IX87_17035 ENOG4105C6Z Gluconate IX87_17040 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family IX87_17045 ENOG4105C26 Dehydrogenase IX87_17055 ENOG4106HB6 Alpha beta hydrolase IX87_17070 ENOG4105CN1 protease IX87_17085 ENOG4105WVQ Fe-S assembly protein IscX IX87_17105 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) IX87_17125 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) IX87_17145 ENOG4105VW4 glutaredoxin 3 IX87_17155 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) IX87_17160 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) IX87_17170 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH IX87_17175 ENOG4105ENJ RND efflux system, outer membrane lipoprotein IX87_17180 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) IX87_17185 ENOG4105DJY efflux transporter, rnd family, mfp subunit IX87_17210 ENOG4105C7K acetolactate synthase IX87_17215 ENOG4108ZP8 Acetolactate synthase small subunit IX87_17225 ENOG4105BZU Histidine kinase IX87_17265 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) IX87_17280 ENOG4105F8V Hydrolase, tatD family IX87_17285 ENOG4107QM5 aconitate hydratase IX87_17295 ENOG4105CUZ uba thif-type nad fad binding protein IX87_17300 ENOG4107RSM transcriptional regulator IX87_17310 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) IX87_17325 ENOG4106UX7 integral membrane protein IX87_17335 ENOG4105W8H transhydrogenase (subunit alpha IX87_17340 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) IX87_17355 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) IX87_17360 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase IX87_17365 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase IX87_17370 ENOG4105BZU Histidine kinase IX87_17375 ENOG4105C6T cysteine synthase IX87_17390 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) IX87_17400 ENOG4105DXN mazG family IX87_17405 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein IX87_17410 ENOG4105DJ0 Poly(A) Polymerase IX87_17415 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase IX87_17435 ENOG41080Z8 PHOSPHOCARRIER protein IX87_17440 ENOG4105N42 UPF0307 protein IX87_17445 ENOG4105CEY Amp-dependent synthetase and ligase IX87_17460 ENOG4105CYM Glutathione S-transferase IX87_17465 ENOG4105W39 Membrane IX87_17480 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) IX87_17510 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) IX87_17525 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) IX87_17535 ENOG4105C9X ppx gppa phosphatase IX87_17545 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) IX87_17550 ENOG4105II7 pyrroline-5-carboxylate reductase IX87_17555 ENOG4108VIA integral membrane protein IX87_17560 ENOG4105C2M dna polymerase I IX87_17580 ENOG4107QHF type ii secretion system protein e IX87_17585 ENOG4108ZHJ Organic hydroperoxide resistance protein IX87_17590 ENOG4105K56 Transcriptional regulator IX87_17660 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) IX87_17665 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) IX87_17670 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) IX87_17725 ENOG4108Z0R Transferase IX87_17730 ENOG41072GX Peptidase M22 Glycoprotease IX87_17745 ENOG4105C4W S-formylglutathione hydrolase IX87_17755 ENOG4105DJV ribulose-phosphate 3-epimerase IX87_17760 ENOG4108HCJ Hydrolase IX87_17770 ENOG4105E3B Multicopper oxidase IX87_17790 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) IX87_17795 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) IX87_17800 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) IX87_17835 ENOG4105ETT transcriptional Regulator, LysR family IX87_17840 ENOG4105C1G acyl-Coa dehydrogenase IX87_17845 ENOG4107RGD Major Facilitator superfamily IX87_17850 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F IX87_17860 ENOG4107EFR Flavocytochrome c IX87_17865 ENOG4106P55 Transcriptional regulator IX87_17880 ENOG4106P55 Transcriptional regulator IX87_17935 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) IX87_17940 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) IX87_17995 ENOG4105JAB phenazine biosynthesis protein, phzf family IX87_18005 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) IX87_18015 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) IX87_18025 ENOG4107EXC regulatoR IX87_18030 ENOG4105E0F Histidine kinase IX87_18090 ENOG4105GKE subunit e IX87_18095 ENOG4107QIZ NADH dehydrogenase IX87_18100 ENOG4108IEH NADH dehydrogenase subunit g IX87_18115 ENOG4107UFS subunit j IX87_18125 ENOG4105D65 subunit l IX87_18130 ENOG4105C8S subunit m IX87_18150 ENOG4105DUM transcriptional regulator, lysR family IX87_18155 ENOG4105DP0 ferredoxin-NADP reductase IX87_18180 ENOG4105CBX hi0933 family IX87_18185 ENOG4105K6H D-cysteine desulfhydrase IX87_18215 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) IX87_18225 ENOG4105D1F ATP-binding protein IX87_18275 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) IX87_18285 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY IX87_18300 ENOG4105HF0 Membrane IX87_18320 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) IX87_18340 ENOG4106UW1 Major Facilitator superfamily IX87_18345 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase IX87_18350 ENOG4108K4C ec 3.1.3.12 IX87_18355 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) IX87_18365 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) IX87_18370 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) IX87_18380 ENOG4105FE9 pseudouridine synthase IX87_18385 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) IX87_18390 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) IX87_18395 ENOG4107RTD sua5 ycio yrdc ywlc family protein IX87_18400 ENOG4108BPE -transporting atpase IX87_18405 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein IX87_18415 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase IX87_18420 ENOG4105CHR reductase IX87_18430 ENOG4109066 lysm domain bon superfamily protein IX87_18435 ENOG4105DWF phosphomethylpyrimidine kinase IX87_18445 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) IX87_18475 ENOG4105C5T Phosphoribosyl pyrophosphate synthase IX87_18505 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) IX87_18520 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) IX87_18525 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane IX87_18530 ENOG4105C34 Pseudouridine synthase IX87_18535 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase IX87_18620 ENOG4105CDU Replicative dna helicase IX87_18755 ENOG4105E4C Lytic transglycosylase catalytic IX87_18825 ENOG4107QP3 malate synthase g IX87_18835 ENOG4105SG9 biopolymer transport protein, ExbD IX87_18875 ENOG4105DGW oligopeptidase A IX87_18885 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component IX87_18905 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase IX87_18920 ENOG4105K4T epimerase IX87_18925 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) IX87_18945 ENOG4108JA2 transcriptioN-repair coupling factor IX87_18955 ENOG4105F8J Adenylate Guanylate cyclase IX87_18960 ENOG4108ZIT Ferredoxin, 2FE-2S IX87_18975 ENOG4108Z4V iron-sulfur cluster assembly IX87_18980 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins IX87_18990 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family IX87_19010 ENOG4105K70 DNA-binding protein IX87_19015 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) IX87_19020 ENOG4105E7U AraC family transcriptional regulator IX87_19025 ENOG4105EEF Alkane 1-monooxygenase IX87_19030 ENOG4105C1G acyl-Coa dehydrogenase IX87_19035 ENOG4105C1G acyl-Coa dehydrogenase IX87_19050 ENOG4108Z66 YbaK ebsC protein IX87_19065 ENOG4105C0R drug resistance transporter emrb qaca subfamily IX87_19070 ENOG4105DUU IucA IucC family protein IX87_19075 ENOG4105DJU Siderophore biosynthesis protein IX87_19085 ENOG4105JSC dimethylmenaquinone methyltransferase IX87_19115 ENOG4107VXZ Hydrolase IX87_19130 ENOG4108YZT Adenosylcobinamide kinase IX87_19135 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) IX87_19140 ENOG4107TB6 phosphoglycerate mutase IX87_19155 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) IX87_19160 ENOG4107TSN permease IX87_19180 ENOG4105CNM Receptor IX87_19185 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) IX87_19200 ENOG4105CJ1 ABC, transporter IX87_19205 ENOG4107QWP ABC-2 type transporter IX87_19210 ENOG4107QWP ABC-2 type transporter IX87_19235 ENOG4105K59 histidine triad (HIT) protein IX87_19275 ENOG4105F2W methyltransferase IX87_19285 ENOG4105C28 cystathionine IX87_19300 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) IX87_19355 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) IX87_19360 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) IX87_19370 ENOG4105BZU Histidine kinase IX87_19385 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) IX87_19390 ENOG4107R0V Pyruvate dehydrogenase IX87_19395 ENOG4105CPP Dehydrogenase, E1 component IX87_19410 ENOG4105CHR reductase IX87_19420 ENOG4105FFC UPF0187 protein IX87_19430 ENOG4107QPB Beta-lactamase domain protein IX87_19440 ENOG4108VCT Sulfite exporter TauE/SafE IX87_19455 ENOG4105UEI Transcriptional Regulator AraC Family IX87_19460 ENOG4105KVH Transcriptional regulator IX87_19465 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) IX87_19475 ENOG4105FDP GntR family transcriptional regulator IX87_19490 ENOG4106FTQ Taurine ABC transporter, periplasmic IX87_19495 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component IX87_19515 ENOG4105CSH Transporter IX87_19525 ENOG4108IJ0 Aspartate ammonia-lyase IX87_19540 ENOG4107YNJ LysR family Transcriptional regulator IX87_19550 ENOG4105CHU acetyl-coa acetyltransferase IX87_19555 ENOG4105CRW Short chain fatty acid transporter IX87_19570 ENOG4108M0I Transcriptional regulator IX87_19590 ENOG4108IND Tetr family transcriptional regulator IX87_19610 ENOG4105CY2 Citrate transporter IX87_19615 ENOG4105DTD Dehydrogenase IX87_19620 ENOG4105CF7 AraC family transcriptional regulator IX87_19625 ENOG4105D2S major facilitator superfamily IX87_19635 ENOG4105CHR reductase IX87_19660 ENOG4105F57 Anthranilate dioxygenase reductase IX87_19665 ENOG4108YS2 small subunit IX87_19670 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit IX87_19675 ENOG4105F4R Transcriptional regulator mode IX87_19680 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein IX87_19685 ENOG4105E0C molybdate abc transporter IX87_19690 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) IX87_19695 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase IX87_19700 ENOG4105WQI isochorismatase IX87_19710 ENOG4107T31 5'-nucleotidase IX87_19715 ENOG4105CVR type I restriction-modification system IX87_19725 ENOG4107XZC Restriction modification system DNA (Specificity IX87_19765 ENOG4108IGT Dipeptidase IX87_19785 ENOG4107RZC phospholipase d IX87_19915 ENOG4105CV8 reductase IX87_19920 ENOG4105P8F nudix hydrolase IX87_19925 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) IX87_19950 ENOG4105C7K acetolactate synthase IX87_19960 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) IX87_19975 ENOG4107TK4 histidinol-phosphate phosphatase IX87_19990 ENOG4105C7K acetolactate synthase IX87_19995 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) IX87_20005 ENOG41067MG lrgb family IX87_20010 ENOG4105ETE Transcriptional regulator (LacI family IX87_20020 ENOG4108EHX EamA-like transporter family IX87_20030 ENOG4106UW1 Major Facilitator superfamily IX87_20050 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) IX87_20065 ENOG41061TZ Short-chain dehydrogenase reductase Sdr IX87_20075 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) IX87_20095 ENOG4105C26 Dehydrogenase IX87_20120 ENOG4105CJP fad dependent oxidoreductase IX87_20140 ENOG4105CT3 Monooxygenase IX87_20155 ENOG4105BZS acriflavin resistance protein IX87_20160 ENOG4105C1P efflux transporter, rnd family, mfp subunit IX87_20165 ENOG4105CK6 Two component transcriptional regulator (Winged helix family IX87_20170 ENOG4105E0F Histidine kinase IX87_20175 ENOG4108821 RND type efflux pump IX87_20180 ENOG4108R6W Transcriptional regulator, ARAC family IX87_20195 ENOG4108BAS reductase IX87_20200 ENOG4105EQ2 LysR family Transcriptional regulator IX87_20205 ENOG4105ENX hydrolase IX87_20290 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) IX87_20345 ENOG4105C5T Phosphoribosyl pyrophosphate synthase IX87_20365 ENOG4105E0A ABC, transporter IX87_20370 ENOG4105EHG Permease protein IX87_20380 ENOG4105DQ4 alcohol dehydrogenase IX87_20390 ENOG4105CF7 AraC family transcriptional regulator IX87_20395 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase IX87_20405 ENOG4105EXW epimerase dehydratase IX87_20410 ENOG4105DDW LysR family Transcriptional regulator IX87_20420 ENOG4105C01 Dihydroxy-acid dehydratase IX87_20425 ENOG4105CZJ Aldehyde dehydrogenase IX87_20430 ENOG4108V8F Transcriptional regulator, MarR family IX87_20450 ENOG4105CSH Transporter IX87_20455 ENOG4105C26 Dehydrogenase IX87_20460 ENOG4105CNV Aldolase IX87_20475 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase IX87_20480 ENOG4105C26 Dehydrogenase IX87_20490 ENOG4105ERH Fumarylacetoacetate hydrolase IX87_20500 ENOG4105C2C drug resistance transporter, Bcr CflA IX87_20505 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) IX87_20560 ENOG4105CH6 catalase IX87_20575 ENOG4107RGH Aldehyde dehydrogenase IX87_20590 ENOG41062QD Membrane IX87_20610 ENOG4105CEY Amp-dependent synthetase and ligase IX87_20615 ENOG4108JU7 Transcriptional regulator IX87_20630 ENOG4105CHR reductase IX87_20635 ENOG4105C1G acyl-Coa dehydrogenase IX87_20650 ENOG4108R0M Aminoglycoside IX87_20655 ENOG4105CZJ Aldehyde dehydrogenase IX87_20675 ENOG4107EJG GntR family transcriptional regulator IX87_20685 ENOG4108KB2 LysR family Transcriptional regulator IX87_20690 ENOG4105DTQ mandelate racemase muconate lactonizing IX87_20695 ENOG4105NN7 muconolactone delta-isomerase IX87_20705 ENOG4107QP7 CoA-transferase subunit A IX87_20710 ENOG4107QNJ CoA-transferase subunit B IX87_20715 ENOG4105CHU acetyl-coa acetyltransferase IX87_20720 ENOG4105F2Z 3-oxoadipate enol-lactonase IX87_20755 ENOG4105CHR reductase IX87_20765 ENOG4105FUY alpha subunit IX87_20785 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) IX87_20800 ENOG4105DNH Major Facilitator IX87_20825 ENOG4105C1G acyl-Coa dehydrogenase IX87_20830 ENOG4108PTX LysR family Transcriptional regulator IX87_20835 ENOG4107HP6 Transcriptional regulator IX87_20850 ENOG4105MD1 YeeE YedE family protein IX87_20860 ENOG4105DZG Dehydrogenase IX87_20865 ENOG4105TW1 Carbohydrate-selective porin OprB IX87_20870 ENOG4106JPM 3-dehydroshikimate dehydratase IX87_20875 ENOG4105FF2 Type I DHQase IX87_20880 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha IX87_20885 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta IX87_20890 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase IX87_20895 ENOG4105D2S major facilitator superfamily IX87_20900 ENOG4105F2Z 3-oxoadipate enol-lactonase IX87_20905 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase IX87_20910 ENOG4105CHU acetyl-coa acetyltransferase IX87_20915 ENOG4107QNJ CoA-transferase subunit B IX87_20920 ENOG4107QP7 CoA-transferase subunit A IX87_20930 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) IX87_20935 ENOG4107VMU Membrane IX87_20980 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IX87_20995 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) IX87_21005 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit IX87_21010 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) IX87_21040 ENOG4105C7B Threonine dehydratase IX87_21050 ENOG4105CZN Potassium uptake protein IX87_21055 ENOG4105HDD phospholipase IX87_21065 ENOG4105E0K tonB-dependent siderophore receptor IX87_21080 ENOG4105PV3 Inner membrane protein yqiJ IX87_21100 ENOG4105C4M (Ubiquinol oxidase) subunit I IX87_21105 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii IX87_21125 ENOG41068P6 UPF0319 protein IX87_21135 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) IX87_21160 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) IX87_21165 ENOG4105C8Y Acetylornithine aminotransferase IX87_21170 ENOG4105M2J Glutaredoxin IX87_21180 ENOG4105CC0 LysR family Transcriptional regulator IX87_21185 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) IX87_21190 ENOG4105CWM branched-chain amino acid transport system II carrier protein IX87_21215 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) IX87_21220 ENOG4105DE4 1-phosphofructokinase IX87_21225 ENOG4105DM4 PTS System IX87_21290 ENOG4105K70 DNA-binding protein IX87_21340 ENOG4108Z6H mu-like prophage Flumu protein gp27 IX87_21345 ENOG4105CF2 Mu-like prophage FluMu protein GP28 IX87_21365 ENOG4105QIB mu-like prophage Flumu protein gp29 IX87_21370 ENOG4108QUU Morphogenesis Protein IX87_21475 ENOG4108T86 baseplate J family protein IX87_21515 ENOG4105BZU Histidine kinase IX87_21525 ENOG4105D8V Glucose sorbosone dehydrogenase IX87_21530 ENOG4108RAV Conserved protein IX87_21535 ENOG4105CHH sulfate transporter IX87_21560 ENOG4105C85 amino acid IX87_21570 ENOG4105F7P transcriptional regulator AsnC family IX87_21595 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 IX87_21600 ENOG4105VEJ Heat shock protein IX87_21610 ENOG4105Y3E Modulates RecA activity (By similarity) IX87_21620 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) IX87_21645 ENOG4105DZP Membrane-associated zinc metalloprotease IX87_21655 ENOG4105KNE Phosphatidate cytidylyltransferase IX87_21660 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) IX87_21680 ENOG4105CUX Signal transduction histidine kinase IX87_21685 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family IX87_21750 ENOG4105CMR udp-glucose 4-epimerase IX87_21755 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) IX87_21775 ENOG4105T38 integral membrane protein IX87_21780 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IX87_21790 ENOG4105CVM Molybdenum cofactor synthesis domain protein IX87_21795 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) IX87_21810 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) IX87_21830 ENOG4108IFG nitrite reductase, (NAD(P)H) IX87_21835 ENOG4107QZF nitrite reductase NADPH large subunit IX87_21860 ENOG4108HWY Beta-lactamase IX87_21900 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein IX87_21905 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase IX87_21915 ENOG4105D8G Major Facilitator superfamily IX87_21965 ENOG4105E2A Dehydrogenase IX87_21990 ENOG4105NVB glycoside hydrolase, family 19 IX87_22020 ENOG4105E4C Lytic transglycosylase catalytic