locus-tag	class	description
IX88_00050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IX88_00060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IX88_00180	COG0626	cystathionine gamma-synthase activity
IX88_00185	COG0433	COG0433 Predicted ATPase
IX88_00190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX88_00190	COG1017	nitric oxide dioxygenase activity
IX88_00195	COG1959	2 iron, 2 sulfur cluster binding
IX88_00210	COG1301	dicarboxylic acid transport
IX88_00215	COG1946	Acyl-CoA thioesterase
IX88_00235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IX88_00240	COG1040	competence protein
IX88_00245	COG0494	nUDIX hydrolase
IX88_00255	COG0598	Magnesium transport protein CorA
IX88_00265	COG2854	intermembrane phospholipid transfer
IX88_00275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IX88_00280	COG1127	ABC transporter
IX88_00290	COG0513	Belongs to the DEAD box helicase family
IX88_00310	COG0408	coproporphyrinogen oxidase activity
IX88_00325	COG1960	acyl-CoA dehydrogenase activity
IX88_00335	COG1983	PspC domain protein
IX88_00340	COG0517	IMP dehydrogenase activity
IX88_00385	COG0583	DNA-binding transcription factor activity
IX88_00425	COG1012	belongs to the aldehyde dehydrogenase family
IX88_00435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IX88_00440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IX88_00445	COG0833	amino acid
IX88_00475	COG1192	Involved in chromosome partitioning
IX88_00480	COG0628	permease
IX88_00490	COG1289	transmembrane transporter activity
IX88_00505	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX88_00510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IX88_00520	COG0277	FAD linked oxidase domain protein
IX88_00525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IX88_00550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IX88_00555	COG5380	lipid catabolic process
IX88_00575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IX88_00625	COG0194	GDP metabolic process
IX88_00635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX88_00655	COG3307	-O-antigen
IX88_00665	COG4969	Belongs to the N-Me-Phe pilin family
IX88_00675	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IX88_00680	COG1704	LemA family
IX88_00690	COG0493	'glutamate synthase
IX88_00695	COG0070	glutamate synthase
IX88_00695	COG0067	glutamate synthase
IX88_00695	COG0069	glutamate synthase activity
IX88_00745	COG2226	methyltransferase
IX88_00760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IX88_00765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IX88_00815	COG0833	amino acid
IX88_00885	COG0488	(ABC) transporter
IX88_00895	COG4221	oxidoreductase activity
IX88_00900	COG0659	secondary active sulfate transmembrane transporter activity
IX88_00910	COG0745	RESPONSE REGULATOR receiver
IX88_00920	COG0427	acetyl-CoA hydrolase
IX88_00950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IX88_00970	COG1132	(ABC) transporter
IX88_00995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IX88_01060	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX88_01065	COG1733	regulation of RNA biosynthetic process
IX88_01105	COG0667	Aldo Keto reductase
IX88_01125	COG0583	DNA-binding transcription factor activity
IX88_01130	COG2814	Major facilitator Superfamily
IX88_01170	COG1335	isochorismatase
IX88_01180	COG1012	belongs to the aldehyde dehydrogenase family
IX88_01185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IX88_01195	COG1113	amino acid transport
IX88_01205	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IX88_01220	COG2814	Major facilitator Superfamily
IX88_01230	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IX88_01230	COG0352	thiamine-phosphate diphosphorylase activity
IX88_01230	COG0351	phosphomethylpyrimidine kinase
IX88_01250	COG1309	transcriptional regulator
IX88_01255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IX88_01260	COG3706	GGDEF domain
IX88_01270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX88_01280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX88_01285	COG3162	membrane
IX88_01290	COG2198	Histidine kinase
IX88_01290	COG0784	Response regulator, receiver
IX88_01290	COG2205	protein histidine kinase activity
IX88_01315	COG1522	sequence-specific DNA binding
IX88_01320	COG1335	isochorismatase
IX88_01325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX88_01335	COG0668	transmembrane transport
IX88_01340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IX88_01345	COG1519	Transferase
IX88_01350	COG1902	pentaerythritol trinitrate reductase activity
IX88_01370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IX88_01395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_01395	COG0426	domain, Protein
IX88_01400	COG4774	siderophore transport
IX88_01405	COG2119	membrane
IX88_01415	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX88_01425	COG4942	peptidase
IX88_01440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IX88_01450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IX88_01470	COG0189	ligase activity
IX88_01490	COG0708	Exodeoxyribonuclease III
IX88_01495	COG1393	Belongs to the ArsC family
IX88_01510	COG3706	GGDEF domain
IX88_01545	COG2351	hydroxyisourate hydrolase activity
IX88_01550	COG2233	PERMEase
IX88_01560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_01570	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IX88_01580	COG3150	esterase
IX88_01645	COG3501	Rhs element vgr protein
IX88_01655	COG2918	glutathione biosynthetic process
IX88_01670	COG2733	membrane
IX88_01675	COG0436	Aminotransferase
IX88_01680	COG0534	Mate efflux family protein
IX88_01765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IX88_01770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IX88_01780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IX88_01785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IX88_01790	COG0546	phosphoglycolate phosphatase activity
IX88_01800	COG0010	Belongs to the arginase family
IX88_01830	COG2188	Transcriptional regulator
IX88_01840	COG0523	cobalamin synthesis protein
IX88_01850	COG1113	amino acid transport
IX88_01860	COG0625	glutathione transferase activity
IX88_01880	COG1683	Conserved Protein
IX88_01885	COG0534	Mate efflux family protein
IX88_01890	COG0385	Bile acid
IX88_01895	COG1335	isochorismatase
IX88_01900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX88_01920	COG2116	formate transmembrane transporter activity
IX88_01925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IX88_01930	COG2133	pyrroloquinoline quinone binding
IX88_01935	COG2983	Belongs to the UPF0260 family
IX88_01955	COG1194	a g-specific adenine glycosylase
IX88_01970	COG2818	Glycosylase
IX88_01975	COG1064	alcohol dehydrogenase
IX88_01980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_01990	COG0583	DNA-binding transcription factor activity
IX88_01995	COG0656	L-ascorbic acid biosynthetic process
IX88_02000	COG2814	Major facilitator Superfamily
IX88_02035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_02050	COG2233	PERMEase
IX88_02055	COG0583	DNA-binding transcription factor activity
IX88_02090	COG0733	neurotransmitter:sodium symporter activity
IX88_02135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IX88_02140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IX88_02145	COG0596	Alpha beta hydrolase
IX88_02170	COG0488	(ABC) transporter
IX88_02175	COG0586	Pfam SNARE associated Golgi protein
IX88_02185	COG0187	DNA topoisomerase II activity
IX88_02195	COG0592	DNA-directed DNA polymerase activity
IX88_02205	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IX88_02220	COG0706	membrane insertase activity
IX88_02235	COG1230	cation diffusion facilitator family transporter
IX88_02240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX88_02260	COG0402	S-adenosylhomocysteine deaminase activity
IX88_02270	COG0754	glutathionylspermidine amidase activity
IX88_02280	COG0861	Integral membrane protein TerC family
IX88_02285	COG0671	phosphoesterase, PA-phosphatase related
IX88_02295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IX88_02310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IX88_02315	COG2951	lytic endotransglycosylase activity
IX88_02345	COG0583	DNA-binding transcription factor activity
IX88_02370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IX88_02410	COG1047	Peptidyl-prolyl cis-trans
IX88_02420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IX88_02425	COG0196	riboflavin kinase activity
IX88_02435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IX88_02440	COG1309	transcriptional regulator
IX88_02445	COG1116	anion transmembrane transporter activity
IX88_02450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX88_02455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IX88_02460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX88_02465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX88_02490	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_02495	COG0546	phosphoglycolate phosphatase activity
IX88_02555	COG3023	N-Acetylmuramoyl-L-alanine amidase
IX88_02560	COG0728	peptidoglycan biosynthetic process
IX88_02590	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IX88_02600	COG1215	transferase activity, transferring glycosyl groups
IX88_02605	COG0438	transferase activity, transferring glycosyl groups
IX88_02615	COG0438	transferase activity, transferring glycosyl groups
IX88_02625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IX88_02630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IX88_02645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IX88_02655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX88_02665	COG2186	Transcriptional regulator
IX88_02675	COG0277	FAD linked oxidase domain protein
IX88_02680	COG1448	Aminotransferase
IX88_02685	COG1802	Transcriptional regulator
IX88_02700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IX88_02755	COG0564	pseudouridine synthase activity
IX88_02780	COG1522	sequence-specific DNA binding
IX88_02795	COG0251	oxidation-reduction process
IX88_02800	COG1113	amino acid transport
IX88_02805	COG1113	amino acid transport
IX88_02825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX88_02830	COG1960	acyl-CoA dehydrogenase activity
IX88_02835	COG1024	Enoyl-CoA hydratase
IX88_02840	COG1024	Enoyl-CoA hydratase
IX88_02845	COG0477	Major facilitator Superfamily
IX88_02850	COG3916	Acyl-homoserine-lactone synthase
IX88_02860	COG2197	response regulator
IX88_02870	COG1960	acyl-CoA dehydrogenase activity
IX88_02875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX88_02875	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IX88_02875	COG3321	synthase
IX88_02875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IX88_02915	COG0271	Belongs to the BolA IbaG family
IX88_02925	COG1192	Involved in chromosome partitioning
IX88_02940	COG0586	Pfam SNARE associated Golgi protein
IX88_02945	COG2259	Doxx family
IX88_02950	COG4399	Belongs to the UPF0754 family
IX88_02955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IX88_02955	COG0519	Catalyzes the synthesis of GMP from XMP
IX88_03000	COG0281	malic enzyme
IX88_03005	COG2837	iron assimilation
IX88_03010	COG1280	lysine exporter protein (LysE YggA)
IX88_03015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IX88_03020	COG1121	(ABC) transporter
IX88_03085	COG0386	Belongs to the glutathione peroxidase family
IX88_03100	COG1309	transcriptional regulator
IX88_03105	COG0697	spore germination
IX88_03115	COG0758	DNA mediated transformation
IX88_03150	COG1309	transcriptional regulator
IX88_03185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IX88_03195	COG0655	NAD(P)H dehydrogenase (quinone) activity
IX88_03230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IX88_03240	COG2814	Major facilitator Superfamily
IX88_03250	COG1253	flavin adenine dinucleotide binding
IX88_03260	COG2860	membrane
IX88_03265	COG0477	Major facilitator Superfamily
IX88_03275	COG0318	PFAM AMP-dependent synthetase and ligase
IX88_03290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IX88_03305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX88_03315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_03320	COG0606	chelatase, subunit chli
IX88_03330	COG0347	Belongs to the P(II) protein family
IX88_03335	COG0004	ammonium transporteR
IX88_03345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX88_03345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX88_03385	COG0795	lipopolysaccharide-transporting ATPase activity
IX88_03390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IX88_03395	COG0793	Belongs to the peptidase S41A family
IX88_03410	COG2197	response regulator
IX88_03420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IX88_03430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX88_03435	COG4974	Belongs to the 'phage' integrase family
IX88_03460	COG0772	Belongs to the SEDS family
IX88_03465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IX88_03470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IX88_03475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IX88_03500	COG0697	spore germination
IX88_03505	COG1538	Outer membrane efflux protein
IX88_03525	COG3275	phosphorelay sensor kinase activity
IX88_03535	COG0181	hydroxymethylbilane synthase activity
IX88_03580	COG1716	ATPase activity
IX88_03585	COG0546	phosphoglycolate phosphatase activity
IX88_03735	COG3316	Transposase and inactivated derivatives
IX88_03745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX88_03765	COG0596	Alpha beta hydrolase
IX88_03770	COG2056	Na+-H+ antiporter family
IX88_03785	COG0326	Molecular chaperone. Has ATPase activity
IX88_03800	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IX88_03855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IX88_03860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IX88_03860	COG2169	Transcriptional regulator
IX88_03890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IX88_03900	COG0497	DNA recombination
IX88_03915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX88_03925	COG0237	dephospho-CoA kinase activity
IX88_03980	COG0195	Participates in both transcription termination and antitermination
IX88_04000	COG2212	antiporter activity
IX88_04010	COG0651	ATP synthesis coupled electron transport
IX88_04015	COG1006	Multisubunit Na H antiporter MnhC subunit
IX88_04020	COG2111	Na H antiporter
IX88_04020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IX88_04035	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IX88_04040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_04055	COG2226	methyltransferase
IX88_04075	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IX88_04080	COG1074	ATP-dependent DNA helicase activity
IX88_04085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IX88_04105	COG0598	Magnesium transport protein CorA
IX88_04110	COG0789	Transcriptional regulator
IX88_04115	COG0484	heat shock protein binding
IX88_04130	COG0475	glutathione-regulated potassium exporter activity
IX88_04130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX88_04135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IX88_04155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX88_04165	COG4535	Mg2 and Co2 transporter CorC
IX88_04170	COG0425	Belongs to the sulfur carrier protein TusA family
IX88_04180	COG0644	oxidoreductase
IX88_04180	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IX88_04190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IX88_04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_04210	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IX88_04245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IX88_04260	COG0534	Mate efflux family protein
IX88_04270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IX88_04280	COG0583	DNA-binding transcription factor activity
IX88_04300	COG1530	ribonuclease E activity
IX88_04310	COG0546	phosphoglycolate phosphatase activity
IX88_04315	COG2378	regulation of single-species biofilm formation
IX88_04320	COG0625	glutathione transferase activity
IX88_04330	COG0583	DNA-binding transcription factor activity
IX88_04385	COG0473	3-isopropylmalate dehydrogenase activity
IX88_04440	COG1301	dicarboxylic acid transport
IX88_04450	COG1560	Kdo2-lipid A biosynthetic process
IX88_04455	COG1280	lysine exporter protein (LysE YggA)
IX88_04480	COG1733	regulation of RNA biosynthetic process
IX88_04505	COG0210	DNA helicase
IX88_04510	COG0724	RNA recognition motif
IX88_04530	COG4651	solute:proton antiporter activity
IX88_04530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX88_04535	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IX88_04540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IX88_04555	COG0788	formyltetrahydrofolate deformylase activity
IX88_04655	COG2813	Specifically methylates the guanine in position
IX88_04655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX88_04665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IX88_04675	COG4774	siderophore transport
IX88_04685	COG0740	serine-type endopeptidase activity
IX88_04705	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IX88_04705	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IX88_04710	COG0280	phosphate acetyltransferase
IX88_04710	COG0857	belongs to the CobB CobQ family
IX88_04715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IX88_04730	COG0800	Aldolase
IX88_04740	COG3265	gluconokinase activity
IX88_04745	COG1012	belongs to the aldehyde dehydrogenase family
IX88_04755	COG2267	carboxylic ester hydrolase activity
IX88_04770	COG0793	Belongs to the peptidase S41A family
IX88_04805	COG1426	Protein conserved in bacteria
IX88_04845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IX88_04855	COG1162	GTPase activity
IX88_04860	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IX88_04875	COG1538	Outer membrane efflux protein
IX88_04880	COG0577	efflux transmembrane transporter activity
IX88_04880	COG1136	(ABC) transporter
IX88_04885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_04910	COG0028	Belongs to the TPP enzyme family
IX88_04915	COG0440	acetolactate synthase activity
IX88_04955	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IX88_04970	COG0084	hydrolase, TatD family'
IX88_04985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IX88_04990	COG0583	DNA-binding transcription factor activity
IX88_05000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX88_05015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IX88_05025	COG2814	Major facilitator Superfamily
IX88_05035	COG0697	spore germination
IX88_05040	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IX88_05045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IX88_05050	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IX88_05065	COG3622	Belongs to the hyi family
IX88_05070	COG2084	Dehydrogenase
IX88_05075	COG1024	Enoyl-CoA hydratase
IX88_05080	COG0784	Response regulator, receiver
IX88_05080	COG2205	protein histidine kinase activity
IX88_05080	COG5002	protein histidine kinase activity
IX88_05100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX88_05110	COG3956	TIGRFAM MazG family protein
IX88_05115	COG1555	photosystem II stabilization
IX88_05120	COG0617	tRNA 3'-terminal CCA addition
IX88_05125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX88_05145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX88_05150	COG3028	Belongs to the UPF0307 family
IX88_05155	COG0318	PFAM AMP-dependent synthetase and ligase
IX88_05170	COG0625	glutathione transferase activity
IX88_05175	COG1238	metal cluster binding
IX88_05190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IX88_05215	COG0072	phenylalanine-tRNA ligase activity
IX88_05240	COG0248	Ppx GppA phosphatase
IX88_05250	COG0037	tRNA processing
IX88_05290	COG1764	response to oxidative stress
IX88_05295	COG1846	Transcriptional regulator
IX88_05305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX88_05365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IX88_05370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IX88_05375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IX88_05450	COG1214	PFAM Peptidase M22, glycoprotease
IX88_05475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IX88_05480	COG0561	phosphatase activity
IX88_05490	COG2132	Multicopper oxidase
IX88_05515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IX88_05520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IX88_05555	COG1063	alcohol dehydrogenase
IX88_05560	COG0583	DNA-binding transcription factor activity
IX88_05565	COG1960	acyl-CoA dehydrogenase activity
IX88_05570	COG2814	Major facilitator Superfamily
IX88_05575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IX88_05580	COG1309	transcriptional regulator
IX88_05595	COG1053	succinate dehydrogenase
IX88_05600	COG0583	DNA-binding transcription factor activity
IX88_05615	COG0583	DNA-binding transcription factor activity
IX88_05625	COG0583	DNA-binding transcription factor activity
IX88_05635	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IX88_05640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_05690	COG0384	phenazine biosynthesis protein PhzF
IX88_05700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IX88_05720	COG0745	RESPONSE REGULATOR receiver
IX88_05725	COG2205	protein histidine kinase activity
IX88_05760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IX88_05790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IX88_05795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IX88_05820	COG0583	DNA-binding transcription factor activity
IX88_05840	COG0668	transmembrane transport
IX88_05850	COG2081	HI0933 family
IX88_05855	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IX88_05885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX88_05885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX88_05895	COG0489	protein tyrosine kinase activity
IX88_05945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX88_05955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IX88_05970	COG0730	response to heat
IX88_05980	COG1196	nuclear chromosome segregation
IX88_06000	COG2223	nitrite transmembrane transporter activity
IX88_06005	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IX88_06010	COG1877	trehalose-phosphatase activity
IX88_06015	COG2226	methyltransferase
IX88_06015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX88_06015	COG0596	Alpha beta hydrolase
IX88_06030	COG4106	trans-aconitate 2-methyltransferase activity
IX88_06045	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IX88_06050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IX88_06055	COG0009	L-threonylcarbamoyladenylate synthase
IX88_06060	COG3101	peptidyl-lysine hydroxylation
IX88_06065	COG1399	metal-binding, possibly nucleic acid-binding protein
IX88_06090	COG1652	LysM domain
IX88_06095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IX88_06095	COG0351	phosphomethylpyrimidine kinase
IX88_06095	COG0352	thiamine-phosphate diphosphorylase activity
IX88_06105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IX88_06135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IX88_06165	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IX88_06180	COG0358	DNA primase activity
IX88_06190	COG0564	pseudouridine synthase activity
IX88_06215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IX88_06230	COG0583	DNA-binding transcription factor activity
IX88_06235	COG0473	3-isopropylmalate dehydrogenase activity
IX88_06255	COG1012	belongs to the aldehyde dehydrogenase family
IX88_06275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX88_06275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IX88_06335	COG0456	acetyltransferase
IX88_06345	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IX88_06350	COG0492	ferredoxin-NADP+ reductase activity
IX88_06355	COG1674	ftsk spoiiie
IX88_06355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IX88_06360	COG1280	lysine exporter protein (LysE YggA)
IX88_06375	COG2894	cell division
IX88_06390	COG0204	Acyl-transferase
IX88_06395	COG2885	chlorophyll binding
IX88_06400	COG0210	DNA helicase
IX88_06410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX88_06425	COG0121	glutamine amidotransferase
IX88_06445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX88_06450	COG0735	belongs to the Fur family
IX88_06480	COG0420	3'-5' exonuclease activity
IX88_06500	COG1090	epimerase
IX88_06515	COG2050	protein possibly involved in aromatic compounds catabolism
IX88_06525	COG2814	Major facilitator Superfamily
IX88_06530	COG0405	Gamma-glutamyltransferase
IX88_06535	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IX88_06555	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IX88_06585	COG0477	Major facilitator Superfamily
IX88_06590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX88_06620	COG0531	amino acid
IX88_06625	COG2040	homocysteine
IX88_06650	COG1309	transcriptional regulator
IX88_06655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX88_06660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX88_06670	COG1607	acyl-coa hydrolase
IX88_06680	COG0523	cobalamin synthesis protein
IX88_06690	COG4681	YaeQ
IX88_06700	COG0726	polysaccharide deacetylase
IX88_06700	COG1649	PFAM Uncharacterised BCR, COG1649
IX88_06705	COG1215	transferase activity, transferring glycosyl groups
IX88_06715	COG1024	Enoyl-CoA hydratase
IX88_06730	COG1414	Transcriptional regulator
IX88_06750	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_06765	COG2271	Major facilitator Superfamily
IX88_06775	COG2267	carboxylic ester hydrolase activity
IX88_06780	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_06795	COG0028	Belongs to the TPP enzyme family
IX88_06805	COG0477	Major facilitator Superfamily
IX88_06810	COG0242	peptide deformylase activity
IX88_06815	COG2066	Belongs to the glutaminase family
IX88_06820	COG2207	Transcriptional regulator
IX88_06825	COG2223	nitrite transmembrane transporter activity
IX88_06840	COG0583	DNA-binding transcription factor activity
IX88_06845	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_06850	COG2271	Major facilitator Superfamily
IX88_06855	COG3959	Transketolase, thiamine diphosphate binding domain
IX88_06860	COG3958	Transketolase
IX88_06880	COG0306	phosphate transporter
IX88_06900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IX88_06945	COG4181	ATPase activity
IX88_06950	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IX88_06975	COG0583	DNA-binding transcription factor activity
IX88_06985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX88_06990	COG1773	rubredoxin
IX88_07040	COG2851	Citrate transporter
IX88_07045	COG1253	flavin adenine dinucleotide binding
IX88_07090	COG0804	urea catabolic process
IX88_07100	COG0830	nickel cation binding
IX88_07115	COG0742	ribosomal rna small subunit methyltransferase
IX88_07120	COG0768	penicillin binding
IX88_07145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IX88_07150	COG2878	Part of a membrane complex involved in electron transport
IX88_07155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IX88_07165	COG3384	dioxygenase
IX88_07200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IX88_07235	COG0006	proline dipeptidase activity
IX88_07240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_07245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_07265	COG1279	arginine transmembrane transporter activity
IX88_07270	COG0583	DNA-binding transcription factor activity
IX88_07310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IX88_07315	COG1388	LysM domain
IX88_07315	COG0741	lytic transglycosylase activity
IX88_07315	COG1388	LysM domain
IX88_07315	COG0741	lytic transglycosylase activity
IX88_07320	COG4166	transmembrane transport
IX88_07325	COG4174	ABC transporter (Permease)
IX88_07330	COG4239	(ABC) transporter, permease
IX88_07335	COG4172	Belongs to the ABC transporter superfamily
IX88_07365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IX88_07375	COG3706	GGDEF domain
IX88_07375	COG2203	Gaf domain
IX88_07375	COG5001	Diguanylate cyclase
IX88_07375	COG4251	negative regulation of phosphorylation
IX88_07385	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX88_07385	COG1902	pentaerythritol trinitrate reductase activity
IX88_07395	COG0582	viral genome integration into host DNA
IX88_07425	COG3328	transposase activity
IX88_07485	COG0789	Transcriptional regulator
IX88_07540	COG2184	nucleotidyltransferase activity
IX88_07550	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IX88_07555	COG0732	type I restriction modification DNA specificity domain
IX88_07575	COG1309	transcriptional regulator
IX88_07610	COG3501	Rhs element vgr protein
IX88_07665	COG1113	amino acid transport
IX88_07675	COG0531	amino acid
IX88_07700	COG1012	belongs to the aldehyde dehydrogenase family
IX88_07720	COG1113	amino acid transport
IX88_07735	COG0697	spore germination
IX88_07740	COG2721	sulfolactate sulfo-lyase activity
IX88_07745	COG2271	Major facilitator Superfamily
IX88_07750	COG4948	Mandelate Racemase Muconate Lactonizing
IX88_07760	COG1012	belongs to the aldehyde dehydrogenase family
IX88_07765	COG2186	Transcriptional regulator
IX88_07790	COG1960	acyl-CoA dehydrogenase activity
IX88_07800	COG1012	belongs to the aldehyde dehydrogenase family
IX88_07805	COG1024	Enoyl-CoA hydratase
IX88_07810	COG2814	Major facilitator Superfamily
IX88_07825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX88_07870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IX88_07875	COG2072	flavoprotein involved in K transport
IX88_07880	COG0300	oxidoreductase activity
IX88_07890	COG1309	transcriptional regulator
IX88_07895	COG1741	Belongs to the pirin family
IX88_07910	COG2072	flavoprotein involved in K transport
IX88_07920	COG2252	PERMEase
IX88_07925	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IX88_07930	COG3038	cytochrome b561
IX88_07940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IX88_07960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IX88_07970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IX88_07985	COG0667	Aldo Keto reductase
IX88_07995	COG1765	OsmC-like protein
IX88_08045	COG2885	chlorophyll binding
IX88_08055	COG0625	glutathione transferase activity
IX88_08060	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IX88_08080	COG3634	alkyl hydroperoxide reductase activity
IX88_08090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IX88_08100	COG0450	alkyl hydroperoxide reductase
IX88_08105	COG1643	Atp-dependent helicase
IX88_08120	COG2814	Major facilitator Superfamily
IX88_08125	COG3135	benzoate transporter
IX88_08130	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_08135	COG0633	Ferredoxin
IX88_08135	COG0543	2 iron, 2 sulfur cluster binding
IX88_08140	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IX88_08145	COG4638	Rieske (2fe-2S)
IX88_08150	COG0583	DNA-binding transcription factor activity
IX88_08200	COG1570	exodeoxyribonuclease VII activity
IX88_08235	COG1280	lysine exporter protein (LysE YggA)
IX88_08240	COG1278	Cold shock
IX88_08270	COG2814	Major facilitator Superfamily
IX88_08275	COG1733	regulation of RNA biosynthetic process
IX88_08320	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IX88_08330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IX88_08335	COG1137	ATPase activity
IX88_08340	COG1538	Outer membrane efflux protein
IX88_08380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IX88_08395	COG1522	sequence-specific DNA binding
IX88_08400	COG5006	permease, DMT superfamily
IX88_08410	COG1560	Kdo2-lipid A biosynthetic process
IX88_08420	COG2814	Major facilitator Superfamily
IX88_08440	COG1250	3-hydroxyacyl-CoA dehydrogenase
IX88_08460	COG3501	Rhs element vgr protein
IX88_08495	COG0583	DNA-binding transcription factor activity
IX88_08500	COG1914	H( )-stimulated, divalent metal cation uptake system
IX88_08520	COG4770	biotin carboxylase activity
IX88_08525	COG0038	chloride channel
IX88_08530	COG2831	hemolysin activation secretion protein
IX88_08535	COG3210	domain, Protein
IX88_08585	COG2207	Transcriptional regulator
IX88_08600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IX88_08605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IX88_08610	COG2271	Major facilitator Superfamily
IX88_08615	COG0753	catalase activity
IX88_08620	COG3038	cytochrome b561
IX88_08625	COG0583	DNA-binding transcription factor activity
IX88_08635	COG1414	Transcriptional regulator
IX88_08640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_08650	COG1840	ABC-type Fe3 transport system, periplasmic component
IX88_08655	COG3842	ATPase activity
IX88_08670	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IX88_08675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX88_08680	COG2814	Major facilitator Superfamily
IX88_08685	COG1960	acyl-CoA dehydrogenase activity
IX88_08700	COG1024	Enoyl-CoA hydratase
IX88_08710	COG2814	Major facilitator Superfamily
IX88_08720	COG0183	Belongs to the thiolase family
IX88_08725	COG1250	3-hydroxyacyl-CoA dehydrogenase
IX88_08730	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_08735	COG1024	Enoyl-CoA hydratase
IX88_08740	COG1960	acyl-CoA dehydrogenase activity
IX88_08745	COG2814	Major facilitator Superfamily
IX88_08750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IX88_08755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IX88_08765	COG2814	Major facilitator Superfamily
IX88_08775	COG1960	acyl-CoA dehydrogenase activity
IX88_08790	COG0583	DNA-binding transcription factor activity
IX88_08805	COG1024	Enoyl-CoA hydratase
IX88_08810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IX88_08815	COG1960	acyl-CoA dehydrogenase activity
IX88_08820	COG1309	transcriptional regulator
IX88_08825	COG0318	PFAM AMP-dependent synthetase and ligase
IX88_08845	COG0583	DNA-binding transcription factor activity
IX88_08895	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_08915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IX88_08935	COG2205	protein histidine kinase activity
IX88_08935	COG0784	Response regulator, receiver
IX88_08950	COG0765	amino acid transport
IX88_08955	COG0765	amino acid transport
IX88_08960	COG1126	abc transporter atp-binding protein
IX88_08965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX88_08970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX88_08980	COG1280	lysine exporter protein (LysE YggA)
IX88_08985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IX88_08990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX88_08995	COG1045	serine acetyltransferase
IX88_09010	COG0583	DNA-binding transcription factor activity
IX88_09015	COG0625	glutathione transferase activity
IX88_09020	COG0625	glutathione transferase activity
IX88_09025	COG0583	DNA-binding transcription factor activity
IX88_09035	COG1346	cytolysis
IX88_09055	COG2814	Major facilitator Superfamily
IX88_09065	COG0583	DNA-binding transcription factor activity
IX88_09075	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IX88_09080	COG3052	prosthetic group binding
IX88_09100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IX88_09120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_09130	COG1294	oxidase, subunit
IX88_09135	COG1271	oxidase subunit
IX88_09155	COG0477	Major facilitator Superfamily
IX88_09165	COG4521	taurine ABC transporter
IX88_09170	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IX88_09175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX88_09180	COG2175	clavaminate synthase activity
IX88_09190	COG1953	Uracil, thiamine, allantoin
IX88_09200	COG0583	DNA-binding transcription factor activity
IX88_09210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IX88_09225	COG0640	Transcriptional regulator
IX88_09230	COG0798	PFAM Bile acid sodium symporter
IX88_09235	COG0583	DNA-binding transcription factor activity
IX88_09250	COG3634	alkyl hydroperoxide reductase activity
IX88_09290	COG0436	Aminotransferase
IX88_09300	COG0386	Belongs to the glutathione peroxidase family
IX88_09340	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IX88_09365	COG0012	GTP binding
IX88_09370	COG2011	ABC-type metal ion transport system permease component
IX88_09375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IX88_09385	COG1464	Belongs to the NlpA lipoprotein family
IX88_09415	COG0765	amino acid transport
IX88_09420	COG0765	amino acid transport
IX88_09425	COG1126	abc transporter atp-binding protein
IX88_09435	COG1522	sequence-specific DNA binding
IX88_09450	COG1309	transcriptional regulator
IX88_09490	COG0583	DNA-binding transcription factor activity
IX88_09500	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IX88_09510	COG0697	spore germination
IX88_09535	COG3121	Chaperone
IX88_09540	COG3539	Fimbrial protein
IX88_09565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IX88_09565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IX88_09610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IX88_09620	COG2353	YceI-like domain
IX88_09630	COG3698	Phosphodiester glycosidase
IX88_09645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IX88_09650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IX88_09650	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IX88_09650	COG0506	proline dehydrogenase activity
IX88_09665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX88_09670	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IX88_09690	COG1132	(ABC) transporter
IX88_09695	COG3122	Protein conserved in bacteria
IX88_09700	COG3619	membrane
IX88_09710	COG0640	Transcriptional regulator
IX88_09720	COG2850	peptidyl-arginine hydroxylation
IX88_09725	COG0424	maF-like protein
IX88_09745	COG0191	fructose-bisphosphate aldolase activity
IX88_09750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX88_09765	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IX88_09775	COG1192	Involved in chromosome partitioning
IX88_09780	COG1475	DNA binding
IX88_09785	COG0811	peptide transport
IX88_09795	COG1132	(ABC) transporter
IX88_09800	COG1663	tetraacyldisaccharide 4'-kinase activity
IX88_09820	COG0084	hydrolase, TatD family'
IX88_09835	COG2165	general secretion pathway protein
IX88_09865	COG0590	tRNA wobble adenosine to inosine editing
IX88_09885	COG0776	regulation of translation
IX88_09915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IX88_09920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IX88_09965	COG0339	signal peptide processing
IX88_09970	COG0601	transmembrane transport
IX88_09975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX88_10010	COG0702	epimerase
IX88_10015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IX88_10035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IX88_10065	COG0316	Belongs to the HesB IscA family
IX88_10070	COG0822	iron-sulfur transferase activity
IX88_10095	COG0776	regulation of translation
IX88_10100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX88_10105	COG2207	Transcriptional regulator
IX88_10110	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX88_10115	COG1960	acyl-CoA dehydrogenase activity
IX88_10120	COG1960	acyl-CoA dehydrogenase activity
IX88_10135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IX88_10150	COG2814	Major facilitator Superfamily
IX88_10155	COG4264	IucA IucC family
IX88_10160	COG4264	IucA IucC family
IX88_10170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IX88_10200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX88_10220	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IX88_10225	COG0406	alpha-ribazole phosphatase activity
IX88_10240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX88_10245	COG0730	response to heat
IX88_10265	COG4773	Receptor
IX88_10270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX88_10285	COG1131	(ABC) transporter
IX88_10290	COG0842	Transport permease protein
IX88_10295	COG0842	Transport permease protein
IX88_10350	COG2226	methyltransferase
IX88_10375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IX88_10410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IX88_10420	COG0133	tryptophan synthase activity
IX88_10435	COG3706	GGDEF domain
IX88_10450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IX88_10455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IX88_10460	COG0022	dehydrogenase e1 component
IX88_10465	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX88_10470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX88_10480	COG1063	alcohol dehydrogenase
IX88_10485	COG3781	membrane
IX88_10495	COG3453	Protein conserved in bacteria
IX88_10495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_10505	COG0730	response to heat
IX88_10520	COG3708	Transcriptional regulator
IX88_10520	COG2207	Transcriptional regulator
IX88_10525	COG1733	regulation of RNA biosynthetic process
IX88_10530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IX88_10555	COG4521	taurine ABC transporter
IX88_10565	COG0477	Major facilitator Superfamily
IX88_10575	COG1027	Aspartate ammonia-lyase
IX88_10590	COG0583	DNA-binding transcription factor activity
IX88_10595	COG0583	DNA-binding transcription factor activity
IX88_10600	COG0183	Belongs to the thiolase family
IX88_10605	COG2031	fatty acid transporter
IX88_10620	COG0583	DNA-binding transcription factor activity
IX88_10640	COG1309	transcriptional regulator
IX88_10650	COG2610	gluconate transmembrane transporter activity
IX88_10655	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_10660	COG2207	Transcriptional regulator
IX88_10670	COG0412	Dienelactone hydrolase
IX88_10675	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_10685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_10700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX88_10700	COG0543	2 iron, 2 sulfur cluster binding
IX88_10705	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IX88_10710	COG4638	Rieske (2fe-2S)
IX88_10720	COG0725	ABC transporter, periplasmic molybdate-binding protein
IX88_10725	COG4149	molybdate abc transporter
IX88_10730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IX88_10735	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_10740	COG3433	isochorismatase activity
IX88_10740	COG1535	isochorismatase
IX88_10800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IX88_10815	COG0753	catalase activity
IX88_10825	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IX88_10850	COG3539	Fimbrial protein
IX88_10930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX88_10935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_10940	COG0745	RESPONSE REGULATOR receiver
IX88_10965	COG2207	Transcriptional regulator
IX88_10980	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_11030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IX88_11085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IX88_11105	COG1120	ATPase activity
IX88_11120	COG1064	alcohol dehydrogenase
IX88_11135	COG2207	Transcriptional regulator
IX88_11140	COG2084	Dehydrogenase
IX88_11150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IX88_11155	COG0583	DNA-binding transcription factor activity
IX88_11165	COG0129	dihydroxy-acid dehydratase activity
IX88_11170	COG1012	belongs to the aldehyde dehydrogenase family
IX88_11210	COG0583	DNA-binding transcription factor activity
IX88_11260	COG3210	domain, Protein
IX88_11265	COG2831	hemolysin activation secretion protein
IX88_11275	COG1473	amidohydrolase
IX88_11285	COG0475	glutathione-regulated potassium exporter activity
IX88_11285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX88_11295	COG0583	DNA-binding transcription factor activity
IX88_11300	COG1335	isochorismatase
IX88_11310	COG1309	transcriptional regulator
IX88_11350	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX88_11350	COG1902	pentaerythritol trinitrate reductase activity
IX88_11365	COG1012	belongs to the aldehyde dehydrogenase family
IX88_11385	COG2186	Transcriptional regulator
IX88_11395	COG0583	DNA-binding transcription factor activity
IX88_11400	COG4948	Mandelate Racemase Muconate Lactonizing
IX88_11405	COG4829	muconolactone delta-isomerase
IX88_11415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IX88_11420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IX88_11425	COG0183	Belongs to the thiolase family
IX88_11430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX88_11440	COG1012	belongs to the aldehyde dehydrogenase family
IX88_11450	COG3733	amine oxidase
IX88_11460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_11470	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_11480	COG4638	Rieske (2fe-2S)
IX88_11500	COG0154	amidase activity
IX88_11515	COG2814	Major facilitator Superfamily
IX88_11540	COG1960	acyl-CoA dehydrogenase activity
IX88_11545	COG0583	DNA-binding transcription factor activity
IX88_11550	COG1414	Transcriptional regulator
IX88_11565	COG2391	methyltransferase activity
IX88_11575	COG4993	Dehydrogenase
IX88_11580	COG3659	wide pore channel activity
IX88_11585	COG3420	alginic acid biosynthetic process
IX88_11590	COG0710	3-dehydroquinate dehydratase activity
IX88_11595	COG3485	protocatechuate 3,4-dioxygenase
IX88_11600	COG3485	protocatechuate 3,4-dioxygenase
IX88_11605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IX88_11610	COG2271	Major facilitator Superfamily
IX88_11615	COG0596	Alpha beta hydrolase
IX88_11620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IX88_11625	COG0183	Belongs to the thiolase family
IX88_11630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IX88_11635	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IX88_11645	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IX88_11650	COG2323	membrane
IX88_11695	COG1902	pentaerythritol trinitrate reductase activity
IX88_11695	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX88_11710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX88_11720	COG0542	response to heat
IX88_11725	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IX88_11755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IX88_11760	COG0569	domain protein
IX88_11765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IX88_11785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX88_11795	COG1585	Membrane protein implicated in regulation of membrane protease activity
IX88_11810	COG1294	oxidase, subunit
IX88_11815	COG4890	Cyd operon protein YbgT
IX88_11830	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IX88_11840	COG0552	protein localization to endoplasmic reticulum
IX88_11865	COG0516	GMP reductase activity
IX88_11865	COG0517	IMP dehydrogenase activity
IX88_11870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IX88_11875	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IX88_11885	COG0583	DNA-binding transcription factor activity
IX88_11890	COG0024	Methionine aminopeptidase
IX88_11920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IX88_11920	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX88_11925	COG1105	Belongs to the carbohydrate kinase PfkB family
IX88_11930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX88_11930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX88_11930	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IX88_11945	COG5001	Diguanylate cyclase
IX88_11945	COG3300	MHYT domain
IX88_11960	COG2135	peptidase activity
IX88_11965	COG0659	secondary active sulfate transmembrane transporter activity
IX88_11980	COG1113	amino acid transport
IX88_11990	COG1522	sequence-specific DNA binding
IX88_12015	COG1011	Hydrolase
IX88_12020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IX88_12030	COG2137	regulation of response to DNA damage stimulus
IX88_12045	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX88_12065	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX88_12080	COG0575	Belongs to the CDS family
IX88_12085	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IX88_12105	COG3852	Histidine kinase
IX88_12110	COG2204	response regulator
IX88_12165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IX88_12170	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IX88_12190	COG0697	spore germination
IX88_12195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_12205	COG0303	'Molybdopterin
IX88_12210	COG0315	cyclic pyranopterin monophosphate synthase activity
IX88_12210	COG0521	Mo-molybdopterin cofactor biosynthetic process
IX88_12225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IX88_12230	COG0243	molybdopterin cofactor binding
IX88_12240	COG0243	molybdopterin cofactor binding
IX88_12245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX88_12250	COG2146	nitrite reductase [NAD(P)H] activity
IX88_12250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX88_12260	COG0745	RESPONSE REGULATOR receiver
IX88_12265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX88_12265	COG1116	anion transmembrane transporter activity
IX88_12280	COG0511	ligase activity, forming carbon-carbon bonds
IX88_12295	COG2814	Major facilitator Superfamily
IX88_12325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IX88_12425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IX88_12720	COG0069	glutamate synthase activity
IX88_12740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IX88_12750	COG1454	alcohol dehydrogenase
IX88_12755	COG0824	Thioesterase
IX88_12770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IX88_12810	COG0183	Belongs to the thiolase family
IX88_12820	COG0583	DNA-binding transcription factor activity
IX88_12835	COG1522	sequence-specific DNA binding
IX88_12840	COG3135	benzoate transporter
IX88_12850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IX88_12870	COG0589	response to stress
IX88_12875	COG0488	(ABC) transporter
IX88_12895	COG4773	Receptor
IX88_12925	COG0668	transmembrane transport
IX88_12935	COG1309	transcriptional regulator
IX88_12945	COG2801	Transposase and inactivated derivatives
IX88_12960	COG1605	Chorismate mutase
IX88_13000	COG0308	aminopeptidase N
IX88_13020	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IX88_13030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IX88_13035	COG1454	alcohol dehydrogenase
IX88_13055	COG0531	amino acid
IX88_13060	COG4303	Ethanolamine ammonia lyase large subunit
IX88_13065	COG4302	ethanolamine ammonia-lyase activity
IX88_13070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IX88_13070	COG0519	Catalyzes the synthesis of GMP from XMP
IX88_13100	COG0697	spore germination
IX88_13105	COG1923	regulation of RNA biosynthetic process
IX88_13115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IX88_13120	COG0802	atpase or kinase
IX88_13140	COG1187	pseudouridine synthase activity
IX88_13155	COG0583	DNA-binding transcription factor activity
IX88_13170	COG2814	Major facilitator Superfamily
IX88_13175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX88_13200	COG0729	surface antigen
IX88_13220	COG0174	glutamine synthetase
IX88_13225	COG0745	RESPONSE REGULATOR receiver
IX88_13230	COG2205	protein histidine kinase activity
IX88_13235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IX88_13240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IX88_13245	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IX88_13270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_13275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX88_13280	COG1960	acyl-CoA dehydrogenase activity
IX88_13295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX88_13300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX88_13320	COG0583	DNA-binding transcription factor activity
IX88_13335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IX88_13345	COG3658	cytochrome
IX88_13350	COG1215	transferase activity, transferring glycosyl groups
IX88_13355	COG1649	PFAM Uncharacterised BCR, COG1649
IX88_13355	COG0726	polysaccharide deacetylase
IX88_13380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IX88_13385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IX88_13395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IX88_13420	COG0305	Participates in initiation and elongation during chromosome replication
IX88_13425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IX88_13435	COG1305	Transglutaminase-like
IX88_13445	COG2308	Evidence 4 Homologs of previously reported genes of
IX88_13480	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IX88_13485	COG0138	bifunctional purine biosynthesis protein purh
IX88_13490	COG0151	Belongs to the GarS family
IX88_13495	COG1464	Belongs to the NlpA lipoprotein family
IX88_13500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IX88_13505	COG2011	ABC-type metal ion transport system permease component
IX88_13510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_13520	COG1301	dicarboxylic acid transport
IX88_13550	COG1794	racemase activity, acting on amino acids and derivatives
IX88_13570	COG0745	RESPONSE REGULATOR receiver
IX88_13575	COG0642	Histidine kinase
IX88_13580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IX88_13590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IX88_13630	COG2351	hydroxyisourate hydrolase activity
IX88_13640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IX88_13640	COG3008	intermembrane lipid transfer
IX88_13645	COG2995	paraquat-inducible protein a
IX88_13675	COG0477	Major facilitator Superfamily
IX88_13725	COG2186	Transcriptional regulator
IX88_13735	COG0786	glutamate:sodium symporter activity
IX88_13740	COG3243	poly(R)-hydroxyalkanoic acid synthase
IX88_13765	COG3111	PFAM Bacterial OB fold (BOF) protein
IX88_13845	COG2831	hemolysin activation secretion protein
IX88_13895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IX88_13900	COG1610	YqeY-like protein
IX88_13905	COG4783	chaperone-mediated protein folding
IX88_13930	COG1286	toxin biosynthetic process
IX88_14180	COG0305	Participates in initiation and elongation during chromosome replication
IX88_14300	COG0778	Nitroreductase
IX88_14310	COG0513	Belongs to the DEAD box helicase family
IX88_14330	COG2363	Small membrane protein
IX88_14360	COG1234	tRNA 3'-trailer cleavage
IX88_14365	COG2195	Cleaves the N-terminal amino acid of tripeptides
IX88_14375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IX88_14385	COG2819	hydrolase of the alpha beta superfamily
IX88_14390	COG1960	acyl-CoA dehydrogenase activity
IX88_14395	COG1301	dicarboxylic acid transport
IX88_14405	COG3139	Protein of unknown function (DUF1315)
IX88_14410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IX88_14415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IX88_14425	COG0494	nUDIX hydrolase
IX88_14435	COG0642	Histidine kinase
IX88_14440	COG0745	RESPONSE REGULATOR receiver
IX88_14445	COG3111	PFAM Bacterial OB fold (BOF) protein
IX88_14460	COG1720	tRNA m6t6A37 methyltransferase activity
IX88_14475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_14485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IX88_14505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_14515	COG1538	Outer membrane efflux protein
IX88_14545	COG1131	(ABC) transporter
IX88_14550	COG0842	Transport permease protein
IX88_14565	COG0772	Belongs to the SEDS family
IX88_14570	COG2951	lytic endotransglycosylase activity
IX88_14595	COG2207	Transcriptional regulator
IX88_14610	COG0052	Belongs to the universal ribosomal protein uS2 family
IX88_14615	COG0024	Methionine aminopeptidase
IX88_14625	COG2223	nitrite transmembrane transporter activity
IX88_14640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX88_14645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IX88_14650	COG1960	acyl-CoA dehydrogenase activity
IX88_14665	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IX88_14670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IX88_14675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IX88_14695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX88_14700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IX88_14705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IX88_14740	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IX88_14755	COG3104	oligopeptide transport
IX88_14765	COG0582	viral genome integration into host DNA
IX88_14805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IX88_14830	COG2314	TM2 domain
IX88_14885	COG3566	protein conserved in bacteria
IX88_14900	COG3567	Phage-associated protein, HI1409 family
IX88_14905	COG5410	chromosome segregation
IX88_15080	COG0512	Glutamine amidotransferase of anthranilate synthase
IX88_15085	COG0308	aminopeptidase N
IX88_15115	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IX88_15145	COG3739	integral membrane protein
IX88_15160	COG1169	isochorismate synthase
IX88_15170	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IX88_15175	COG5265	(ABC) transporter
IX88_15180	COG1132	(ABC) transporter
IX88_15195	COG3433	isochorismatase activity
IX88_15195	COG1535	isochorismatase
IX88_15200	COG1021	2,3-dihydroxybenzoate-AMP ligase
IX88_15205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX88_15215	COG4774	siderophore transport
IX88_15220	COG4607	ABC-type enterochelin transport system periplasmic component
IX88_15225	COG4604	ABC transporter, ATP-binding protein
IX88_15230	COG4605	iron ion homeostasis
IX88_15235	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IX88_15240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX88_15255	COG2964	Protein conserved in bacteria
IX88_15265	COG1741	Belongs to the pirin family
IX88_15295	COG2879	small protein
IX88_15300	COG1966	Carbon starvation protein
IX88_15320	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IX88_15345	COG1067	ATP-dependent peptidase activity
IX88_15350	COG0583	DNA-binding transcription factor activity
IX88_15375	COG1686	Belongs to the peptidase S11 family
IX88_15380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IX88_15415	COG0616	signal peptide processing
IX88_15420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IX88_15430	COG0573	inorganic phosphate transmembrane transporter activity
IX88_15435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IX88_15440	COG1113	amino acid transport
IX88_15445	COG3961	Belongs to the TPP enzyme family
IX88_15450	COG1522	sequence-specific DNA binding
IX88_15460	COG0076	glutamate decarboxylase activity
IX88_15465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IX88_15490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX88_15525	COG0352	thiamine-phosphate diphosphorylase activity
IX88_15550	COG0612	Peptidase, M16
IX88_15565	COG0583	DNA-binding transcription factor activity
IX88_15570	COG0477	Major facilitator Superfamily
IX88_15595	COG1187	pseudouridine synthase activity
IX88_15610	COG1686	Belongs to the peptidase S11 family
IX88_15615	COG1252	NADH dehydrogenase
IX88_15625	COG0415	Belongs to the DNA photolyase family
IX88_15640	COG1215	transferase activity, transferring glycosyl groups
IX88_15670	COG2070	2-Nitropropane dioxygenase
IX88_15725	COG0556	nucleotide-excision repair
IX88_15770	COG4221	oxidoreductase activity
IX88_15780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IX88_15785	COG1381	Involved in DNA repair and RecF pathway recombination
IX88_15795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IX88_15810	COG0681	Belongs to the peptidase S26 family
IX88_15825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX88_15845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IX88_15850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IX88_15855	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IX88_15865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IX88_15870	COG4208	sulfate ABC transporter
IX88_15875	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IX88_15880	COG0583	DNA-binding transcription factor activity
IX88_15885	COG4625	pathogenesis
IX88_15900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IX88_15915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IX88_15925	COG1051	belongs to the nudix hydrolase family
IX88_15925	COG1056	cytidyltransferase-related domain
IX88_15930	COG1024	Enoyl-CoA hydratase
IX88_15935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IX88_15945	COG2814	Major facilitator Superfamily
IX88_15950	COG0047	phosphoribosylformylglycinamidine synthase activity
IX88_15950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IX88_15970	COG1473	amidohydrolase
IX88_15975	COG0824	Thioesterase
IX88_15995	COG0823	Involved in the tonB-independent uptake of proteins
IX88_16015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX88_16050	COG0628	permease
IX88_16060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IX88_16065	COG0596	Alpha beta hydrolase
IX88_16070	COG0616	signal peptide processing
IX88_16070	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IX88_16080	COG0658	competence protein
IX88_16080	COG2333	competence protein COMEC
IX88_16085	COG1136	(ABC) transporter
IX88_16090	COG4591	ABC-type transport system involved in lipoprotein release permease component
IX88_16120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_16140	COG0463	Glycosyl transferase, family 2
IX88_16170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IX88_16175	COG1280	lysine exporter protein (LysE YggA)
IX88_16185	COG0019	diaminopimelate decarboxylase activity
IX88_16195	COG1113	amino acid transport
IX88_16210	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IX88_16220	COG3339	Conserved Protein
IX88_16225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IX88_16230	COG0243	molybdopterin cofactor binding
IX88_16235	COG1929	Belongs to the glycerate kinase type-1 family
IX88_16245	COG0300	oxidoreductase activity
IX88_16250	COG0778	Nitroreductase
IX88_16275	COG2801	Transposase and inactivated derivatives
IX88_16290	COG0789	Transcriptional regulator
IX88_16305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX88_16320	COG1309	transcriptional regulator
IX88_16410	COG0582	viral genome integration into host DNA
IX88_16420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX88_16445	COG0741	lytic transglycosylase activity
IX88_16465	COG0584	glycerophosphoryl diester phosphodiesterase
IX88_16470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_16490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IX88_16510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IX88_16515	COG0477	Major facilitator Superfamily
IX88_16570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IX88_16575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IX88_16600	COG0505	Belongs to the CarA family
IX88_16620	COG0589	response to stress
IX88_16635	COG2843	Capsule synthesis protein
IX88_16660	COG2321	neutral zinc metallopeptidase
IX88_16665	COG2354	Protein conserved in bacteria
IX88_16685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX88_16700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IX88_16705	COG1053	succinate dehydrogenase
IX88_16710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IX88_16715	COG2009	succinate dehydrogenase
IX88_16755	COG2921	Belongs to the UPF0250 family
IX88_16760	COG0321	lipoyl(octanoyl) transferase activity
IX88_16775	COG0531	amino acid
IX88_16785	COG1733	regulation of RNA biosynthetic process
IX88_16790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IX88_16795	COG1648	precorrin-2 dehydrogenase activity
IX88_16795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IX88_16810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IX88_16840	COG0671	phosphoesterase, PA-phosphatase related
IX88_16845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_16855	COG1538	Outer membrane efflux protein
IX88_16860	COG0393	Putative heavy-metal-binding
IX88_16865	COG0393	Putative heavy-metal-binding
IX88_16875	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_16885	COG0525	valine-tRNA ligase activity
IX88_16905	COG0583	DNA-binding transcription factor activity
IX88_16910	COG0004	ammonium transporteR
IX88_16920	COG0642	Histidine kinase
IX88_16925	COG0745	RESPONSE REGULATOR receiver
IX88_16930	COG2194	sulfuric ester hydrolase activity
IX88_16955	COG1752	Esterase of the alpha-beta hydrolase superfamily
IX88_16970	COG2315	Protein conserved in bacteria
IX88_16975	COG0142	geranyltranstransferase activity
IX88_16980	COG2828	Protein conserved in bacteria
IX88_16985	COG1113	amino acid transport
IX88_17005	COG2207	Transcriptional regulator
IX88_17030	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX88_17050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX88_17060	COG1530	ribonuclease E activity
IX88_17065	COG0424	maF-like protein
IX88_17070	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IX88_17075	COG1792	Involved in formation and maintenance of cell shape
IX88_17080	COG1077	Cell shape determining protein MreB Mrl
IX88_17085	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IX88_17095	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IX88_17120	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IX88_17125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IX88_17130	COG1752	Esterase of the alpha-beta hydrolase superfamily
IX88_17135	COG1115	amino acid carrier protein
IX88_17155	COG2814	Major facilitator Superfamily
IX88_17160	COG1289	transmembrane transporter activity
IX88_17210	COG1376	ErfK ybiS ycfS ynhG family protein
IX88_17215	COG2832	Protein of unknown function (DUF454)
IX88_17225	COG5510	response to toxic substance
IX88_17245	COG0840	transmembrane signaling receptor activity
IX88_17285	COG3422	double-strand break repair
IX88_17290	COG2824	Alkylphosphonate utilization operon protein PhnA
IX88_17295	COG3189	MarR family transcriptional regulator
IX88_17305	COG0354	folic acid binding
IX88_17310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX88_17320	COG0679	Auxin Efflux Carrier
IX88_17325	COG1902	pentaerythritol trinitrate reductase activity
IX88_17330	COG4772	TonB-dependent receptor
IX88_17335	COG2094	Belongs to the DNA glycosylase MPG family
IX88_17365	COG2233	PERMEase
IX88_17375	COG0833	amino acid
IX88_17380	COG1690	Belongs to the RtcB family
IX88_17390	COG2885	chlorophyll binding
IX88_17390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IX88_17400	COG0183	Belongs to the thiolase family
IX88_17420	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX88_17440	COG2207	Transcriptional regulator
IX88_17445	COG0183	Belongs to the thiolase family
IX88_17475	COG1272	protein, Hemolysin III
IX88_17480	COG0477	Major facilitator Superfamily
IX88_17495	COG0450	alkyl hydroperoxide reductase
IX88_17515	COG0285	dihydrofolate synthase activity
IX88_17550	COG0133	tryptophan synthase activity
IX88_17560	COG4206	TonB-dependent receptor
IX88_17565	COG2096	Adenosyltransferase
IX88_17570	COG0584	glycerophosphoryl diester phosphodiesterase
IX88_17585	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IX88_17590	COG0745	RESPONSE REGULATOR receiver
IX88_17595	COG2205	protein histidine kinase activity
IX88_17605	COG1960	acyl-CoA dehydrogenase activity
IX88_17610	COG1960	acyl-CoA dehydrogenase activity
IX88_17655	COG0438	transferase activity, transferring glycosyl groups
IX88_17660	COG1216	Glycosyl transferase, family 2
IX88_17665	COG0438	transferase activity, transferring glycosyl groups
IX88_17685	COG0438	transferase activity, transferring glycosyl groups
IX88_17690	COG0726	polysaccharide deacetylase
IX88_17705	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IX88_17750	COG1862	Preprotein translocase
IX88_17760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX88_17765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IX88_17775	COG3781	membrane
IX88_17780	COG0613	PHP domain protein
IX88_17790	COG2350	Protein conserved in bacteria
IX88_17820	COG1607	acyl-coa hydrolase
IX88_17835	COG3453	Protein conserved in bacteria
IX88_17835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_17880	COG2199	diguanylate cyclase activity
IX88_17890	COG1408	metallophosphoesterase
IX88_17895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IX88_17905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IX88_17925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IX88_17930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IX88_17935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IX88_17945	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IX88_17955	COG2969	positive regulation of protein catabolic process
IX88_17970	COG1024	Enoyl-CoA hydratase
IX88_17975	COG1960	acyl-CoA dehydrogenase activity
IX88_17980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IX88_17995	COG1309	transcriptional regulator
IX88_18000	COG1960	acyl-CoA dehydrogenase activity
IX88_18045	COG1183	phosphatidylcholine synthase activity
IX88_18050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IX88_18080	COG0739	heme binding
IX88_18080	COG1196	nuclear chromosome segregation
IX88_18080	COG0741	lytic transglycosylase activity
IX88_18090	COG1702	phosphate starvation-inducible protein PhoH
IX88_18125	COG1295	ribonuclease BN
IX88_18130	COG0697	spore germination
IX88_18135	COG2169	Transcriptional regulator
IX88_18140	COG0179	Fumarylacetoacetate (FAA) hydrolase
IX88_18190	COG0557	exoribonuclease II activity
IX88_18195	COG0339	signal peptide processing
IX88_18200	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IX88_18235	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IX88_18240	COG1960	acyl-CoA dehydrogenase activity
IX88_18265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IX88_18275	COG0257	Belongs to the bacterial ribosomal protein bL36 family