locus-tag	class	description
LXM98_00010	COG0592	DNA-directed DNA polymerase activity
LXM98_00020	COG0187	DNA topoisomerase II activity
LXM98_00030	COG0586	Pfam SNARE associated Golgi protein
LXM98_00035	COG0488	(ABC) transporter
LXM98_00060	COG0596	Alpha beta hydrolase
LXM98_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LXM98_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LXM98_00160	COG2233	PERMEase
LXM98_00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM98_00210	COG2814	Major facilitator Superfamily
LXM98_00215	COG0656	L-ascorbic acid biosynthetic process
LXM98_00220	COG0583	DNA-binding transcription factor activity
LXM98_00235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXM98_00240	COG1064	alcohol dehydrogenase
LXM98_00245	COG2818	Glycosylase
LXM98_00260	COG1194	a g-specific adenine glycosylase
LXM98_00280	COG2983	Belongs to the UPF0260 family
LXM98_00285	COG2133	pyrroloquinoline quinone binding
LXM98_00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LXM98_00295	COG2116	formate transmembrane transporter activity
LXM98_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LXM98_00320	COG1335	isochorismatase
LXM98_00325	COG0385	Bile acid
LXM98_00330	COG0534	Mate efflux family protein
LXM98_00335	COG1683	Conserved Protein
LXM98_00355	COG0625	glutathione transferase activity
LXM98_00365	COG1113	amino acid transport
LXM98_00375	COG0523	cobalamin synthesis protein
LXM98_00385	COG2188	Transcriptional regulator
LXM98_00415	COG0010	Belongs to the arginase family
LXM98_00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LXM98_00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LXM98_00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LXM98_00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LXM98_00550	COG0534	Mate efflux family protein
LXM98_00555	COG0436	Aminotransferase
LXM98_00560	COG2733	membrane
LXM98_00575	COG2918	glutathione biosynthetic process
LXM98_00590	COG1388	LysM domain
LXM98_00590	COG0791	NLP P60 protein
LXM98_00605	COG3150	esterase
LXM98_00615	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_00620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LXM98_00630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXM98_00640	COG2233	PERMEase
LXM98_00645	COG2351	hydroxyisourate hydrolase activity
LXM98_00680	COG3706	GGDEF domain
LXM98_00695	COG1393	Belongs to the ArsC family
LXM98_00700	COG0708	Exodeoxyribonuclease III
LXM98_00720	COG0189	ligase activity
LXM98_00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LXM98_00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LXM98_00765	COG4942	peptidase
LXM98_00775	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXM98_00785	COG2119	membrane
LXM98_00790	COG4774	siderophore transport
LXM98_00795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXM98_00795	COG0426	domain, Protein
LXM98_00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LXM98_00840	COG1902	pentaerythritol trinitrate reductase activity
LXM98_00845	COG1519	Transferase
LXM98_00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LXM98_00855	COG0668	transmembrane transport
LXM98_00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXM98_00870	COG1335	isochorismatase
LXM98_00875	COG1522	sequence-specific DNA binding
LXM98_00880	COG3328	transposase activity
LXM98_00910	COG0784	Response regulator, receiver
LXM98_00910	COG2198	Histidine kinase
LXM98_00910	COG2205	protein histidine kinase activity
LXM98_00915	COG3162	membrane
LXM98_00920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXM98_00930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXM98_00950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LXM98_00955	COG1309	transcriptional regulator
LXM98_00975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXM98_00975	COG0352	thiamine-phosphate diphosphorylase activity
LXM98_00975	COG0351	phosphomethylpyrimidine kinase
LXM98_00985	COG2814	Major facilitator Superfamily
LXM98_01000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LXM98_01010	COG1113	amino acid transport
LXM98_01020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXM98_01025	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_01035	COG1335	isochorismatase
LXM98_01065	COG2814	Major facilitator Superfamily
LXM98_01070	COG0583	DNA-binding transcription factor activity
LXM98_01090	COG0667	Aldo Keto reductase
LXM98_01125	COG1733	regulation of RNA biosynthetic process
LXM98_01130	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXM98_01195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXM98_01210	COG2329	Antibiotic biosynthesis monooxygenase
LXM98_01240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LXM98_01270	COG0427	acetyl-CoA hydrolase
LXM98_01295	COG0659	secondary active sulfate transmembrane transporter activity
LXM98_01300	COG4221	oxidoreductase activity
LXM98_01305	COG2873	o-acetylhomoserine
LXM98_01310	COG0488	(ABC) transporter
LXM98_01395	COG0833	amino acid
LXM98_01440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LXM98_01445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LXM98_01460	COG2226	methyltransferase
LXM98_01510	COG0067	glutamate synthase
LXM98_01510	COG0069	glutamate synthase activity
LXM98_01510	COG0070	glutamate synthase
LXM98_01515	COG0493	'glutamate synthase
LXM98_01525	COG1704	LemA family
LXM98_01530	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LXM98_01550	COG3307	-O-antigen
LXM98_01575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXM98_01590	COG0194	GDP metabolic process
LXM98_01640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LXM98_01660	COG5380	lipid catabolic process
LXM98_01665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LXM98_01690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXM98_01695	COG0277	FAD linked oxidase domain protein
LXM98_01705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LXM98_01710	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXM98_01725	COG1289	transmembrane transporter activity
LXM98_01735	COG0628	permease
LXM98_01740	COG1192	Involved in chromosome partitioning
LXM98_01770	COG0833	amino acid
LXM98_01775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXM98_01780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXM98_01790	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_01830	COG0583	DNA-binding transcription factor activity
LXM98_01875	COG0517	IMP dehydrogenase activity
LXM98_01880	COG1983	PspC domain protein
LXM98_01890	COG1960	acyl-CoA dehydrogenase activity
LXM98_01905	COG0408	coproporphyrinogen oxidase activity
LXM98_01925	COG0513	Belongs to the DEAD box helicase family
LXM98_01935	COG1127	ABC transporter
LXM98_01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LXM98_01950	COG2854	intermembrane phospholipid transfer
LXM98_01960	COG0598	Magnesium transport protein CorA
LXM98_01970	COG0494	nUDIX hydrolase
LXM98_01975	COG1040	competence protein
LXM98_01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LXM98_02000	COG1946	Acyl-CoA thioesterase
LXM98_02005	COG1301	dicarboxylic acid transport
LXM98_02020	COG1959	2 iron, 2 sulfur cluster binding
LXM98_02025	COG1017	nitric oxide dioxygenase activity
LXM98_02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LXM98_02030	COG0433	COG0433 Predicted ATPase
LXM98_02035	COG0626	cystathionine gamma-synthase activity
LXM98_02190	COG1960	acyl-CoA dehydrogenase activity
LXM98_02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LXM98_02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LXM98_02230	COG0339	signal peptide processing
LXM98_02235	COG0557	exoribonuclease II activity
LXM98_02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
LXM98_02285	COG2169	Transcriptional regulator
LXM98_02290	COG0697	spore germination
LXM98_02295	COG1295	ribonuclease BN
LXM98_02330	COG1702	phosphate starvation-inducible protein PhoH
LXM98_02340	COG0739	heme binding
LXM98_02340	COG1196	nuclear chromosome segregation
LXM98_02340	COG0741	lytic transglycosylase activity
LXM98_02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LXM98_02375	COG1183	phosphatidylcholine synthase activity
LXM98_02420	COG1960	acyl-CoA dehydrogenase activity
LXM98_02425	COG1309	transcriptional regulator
LXM98_02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXM98_02445	COG1960	acyl-CoA dehydrogenase activity
LXM98_02465	COG2969	positive regulation of protein catabolic process
LXM98_02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LXM98_02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LXM98_02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LXM98_02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LXM98_02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXM98_02530	COG1408	metallophosphoesterase
LXM98_02540	COG2199	diguanylate cyclase activity
LXM98_02600	COG1607	acyl-coa hydrolase
LXM98_02630	COG2350	Protein conserved in bacteria
LXM98_02640	COG0613	PHP domain protein
LXM98_02645	COG3781	membrane
LXM98_02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LXM98_02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LXM98_02670	COG1862	Preprotein translocase
LXM98_02700	COG2205	protein histidine kinase activity
LXM98_02705	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LXM98_02725	COG0726	polysaccharide deacetylase
LXM98_02730	COG0463	Glycosyl transferase, family 2
LXM98_02735	COG0438	transferase activity, transferring glycosyl groups
LXM98_02800	COG0625	glutathione transferase activity
LXM98_02805	COG0583	DNA-binding transcription factor activity
LXM98_02810	COG1960	acyl-CoA dehydrogenase activity
LXM98_02815	COG1960	acyl-CoA dehydrogenase activity
LXM98_02825	COG2205	protein histidine kinase activity
LXM98_02830	COG0745	RESPONSE REGULATOR receiver
LXM98_02835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LXM98_02855	COG2096	Adenosyltransferase
LXM98_02905	COG0285	dihydrofolate synthase activity
LXM98_02925	COG0450	alkyl hydroperoxide reductase
LXM98_02940	COG0477	Major facilitator Superfamily
LXM98_02945	COG1272	protein, Hemolysin III
LXM98_02975	COG0183	Belongs to the thiolase family
LXM98_02980	COG2207	Transcriptional regulator
LXM98_03000	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM98_03020	COG0183	Belongs to the thiolase family
LXM98_03030	COG2885	chlorophyll binding
LXM98_03030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LXM98_03040	COG1690	Belongs to the RtcB family
LXM98_03045	COG0833	amino acid
LXM98_03055	COG2233	PERMEase
LXM98_03060	COG1217	gtp-binding protein TYPA
LXM98_03085	COG2094	Belongs to the DNA glycosylase MPG family
LXM98_03105	COG1902	pentaerythritol trinitrate reductase activity
LXM98_03120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXM98_03125	COG0354	folic acid binding
LXM98_03135	COG3189	MarR family transcriptional regulator
LXM98_03140	COG2824	Alkylphosphonate utilization operon protein PhnA
LXM98_03145	COG3422	double-strand break repair
LXM98_03190	COG0840	transmembrane signaling receptor activity
LXM98_03210	COG5510	response to toxic substance
LXM98_03220	COG2832	Protein of unknown function (DUF454)
LXM98_03225	COG1376	ErfK ybiS ycfS ynhG family protein
LXM98_03265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LXM98_03275	COG1289	transmembrane transporter activity
LXM98_03280	COG2814	Major facilitator Superfamily
LXM98_03300	COG1115	amino acid carrier protein
LXM98_03305	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXM98_03310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXM98_03315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LXM98_03345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXM98_03355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXM98_03360	COG1077	Cell shape determining protein MreB Mrl
LXM98_03365	COG1792	Involved in formation and maintenance of cell shape
LXM98_03370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LXM98_03375	COG0424	maF-like protein
LXM98_03380	COG1530	ribonuclease E activity
LXM98_03390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXM98_03400	COG0560	Phosphoserine phosphatase
LXM98_03410	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXM98_03435	COG2207	Transcriptional regulator
LXM98_03455	COG1113	amino acid transport
LXM98_03460	COG2828	Protein conserved in bacteria
LXM98_03465	COG0142	geranyltranstransferase activity
LXM98_03470	COG2315	Protein conserved in bacteria
LXM98_03485	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXM98_03505	COG2194	sulfuric ester hydrolase activity
LXM98_03510	COG0745	RESPONSE REGULATOR receiver
LXM98_03515	COG0642	Histidine kinase
LXM98_03525	COG0004	ammonium transporteR
LXM98_03530	COG0583	DNA-binding transcription factor activity
LXM98_03550	COG0525	valine-tRNA ligase activity
LXM98_03560	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_03570	COG0393	Putative heavy-metal-binding
LXM98_03575	COG0393	Putative heavy-metal-binding
LXM98_03580	COG1538	Outer membrane efflux protein
LXM98_03590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM98_03595	COG0671	phosphoesterase, PA-phosphatase related
LXM98_03625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LXM98_03640	COG1648	precorrin-2 dehydrogenase activity
LXM98_03640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LXM98_03645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LXM98_03650	COG1733	regulation of RNA biosynthetic process
LXM98_03660	COG0531	amino acid
LXM98_03675	COG0321	lipoyl(octanoyl) transferase activity
LXM98_03680	COG2921	Belongs to the UPF0250 family
LXM98_03720	COG2009	succinate dehydrogenase
LXM98_03725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LXM98_03730	COG1053	succinate dehydrogenase
LXM98_03735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LXM98_03760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXM98_03780	COG2354	Protein conserved in bacteria
LXM98_03785	COG2321	neutral zinc metallopeptidase
LXM98_03805	COG2843	Capsule synthesis protein
LXM98_03820	COG0589	response to stress
LXM98_03840	COG0505	Belongs to the CarA family
LXM98_03865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXM98_03870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LXM98_03920	COG0477	Major facilitator Superfamily
LXM98_03925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LXM98_03940	COG1597	lipid kinase activity
LXM98_03945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LXM98_03975	COG0584	glycerophosphoryl diester phosphodiesterase
LXM98_03995	COG0741	lytic transglycosylase activity
LXM98_04015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXM98_04030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXM98_04060	COG0778	Nitroreductase
LXM98_04075	COG1929	Belongs to the glycerate kinase type-1 family
LXM98_04080	COG0243	molybdopterin cofactor binding
LXM98_04085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LXM98_04090	COG3339	Conserved Protein
LXM98_04100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LXM98_04115	COG1113	amino acid transport
LXM98_04125	COG0019	diaminopimelate decarboxylase activity
LXM98_04135	COG1280	lysine exporter protein (LysE YggA)
LXM98_04140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LXM98_04170	COG0463	Glycosyl transferase, family 2
LXM98_04190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM98_04225	COG4591	ABC-type transport system involved in lipoprotein release permease component
LXM98_04230	COG1136	(ABC) transporter
LXM98_04235	COG0658	competence protein
LXM98_04235	COG2333	competence protein COMEC
LXM98_04245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LXM98_04245	COG0616	signal peptide processing
LXM98_04250	COG0596	Alpha beta hydrolase
LXM98_04255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LXM98_04265	COG0628	permease
LXM98_04300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXM98_04320	COG0823	Involved in the tonB-independent uptake of proteins
LXM98_04340	COG0824	Thioesterase
LXM98_04345	COG1473	amidohydrolase
LXM98_04365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXM98_04365	COG0047	phosphoribosylformylglycinamidine synthase activity
LXM98_04370	COG2814	Major facilitator Superfamily
LXM98_04380	COG1024	Enoyl-CoA hydratase
LXM98_04385	COG1051	belongs to the nudix hydrolase family
LXM98_04385	COG1056	cytidyltransferase-related domain
LXM98_04395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LXM98_04410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LXM98_04425	COG4625	pathogenesis
LXM98_04430	COG0583	DNA-binding transcription factor activity
LXM98_04435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LXM98_04440	COG4208	sulfate ABC transporter
LXM98_04445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LXM98_04455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LXM98_04460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXM98_04465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LXM98_04485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXM98_04500	COG0681	Belongs to the peptidase S26 family
LXM98_04515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LXM98_04525	COG1381	Involved in DNA repair and RecF pathway recombination
LXM98_04530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LXM98_04540	COG4221	oxidoreductase activity
LXM98_04570	COG0436	Aminotransferase
LXM98_04590	COG0556	nucleotide-excision repair
LXM98_04645	COG2070	2-Nitropropane dioxygenase
LXM98_04675	COG1215	transferase activity, transferring glycosyl groups
LXM98_04690	COG0415	Belongs to the DNA photolyase family
LXM98_04700	COG1252	NADH dehydrogenase
LXM98_04705	COG1686	Belongs to the peptidase S11 family
LXM98_04720	COG1187	pseudouridine synthase activity
LXM98_04745	COG0477	Major facilitator Superfamily
LXM98_04750	COG0583	DNA-binding transcription factor activity
LXM98_04755	COG1823	symporter activity
LXM98_04765	COG0612	Peptidase, M16
LXM98_04790	COG0352	thiamine-phosphate diphosphorylase activity
LXM98_04825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LXM98_04840	COG1309	transcriptional regulator
LXM98_04850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXM98_04855	COG0076	glutamate decarboxylase activity
LXM98_04865	COG1522	sequence-specific DNA binding
LXM98_04870	COG3961	Belongs to the TPP enzyme family
LXM98_04875	COG1113	amino acid transport
LXM98_04880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LXM98_04885	COG0573	inorganic phosphate transmembrane transporter activity
LXM98_04895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXM98_04900	COG0616	signal peptide processing
LXM98_04935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LXM98_04940	COG1686	Belongs to the peptidase S11 family
LXM98_04965	COG0583	DNA-binding transcription factor activity
LXM98_04970	COG1067	ATP-dependent peptidase activity
LXM98_05015	COG1966	Carbon starvation protein
LXM98_05020	COG2879	small protein
LXM98_05055	COG2508	Transcriptional regulator
LXM98_05055	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LXM98_05075	COG1113	amino acid transport
LXM98_05080	COG0583	DNA-binding transcription factor activity
LXM98_05085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXM98_05090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXM98_05100	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_05110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM98_05115	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LXM98_05115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXM98_05150	COG2814	Major facilitator Superfamily
LXM98_05155	COG4948	Mandelate Racemase Muconate Lactonizing
LXM98_05165	COG1309	transcriptional regulator
LXM98_05185	COG1741	Belongs to the pirin family
LXM98_05195	COG2964	Protein conserved in bacteria
LXM98_05210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXM98_05215	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXM98_05220	COG4605	iron ion homeostasis
LXM98_05225	COG4604	ABC transporter, ATP-binding protein
LXM98_05230	COG4607	ABC-type enterochelin transport system periplasmic component
LXM98_05235	COG4774	siderophore transport
LXM98_05245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXM98_05250	COG1021	2,3-dihydroxybenzoate-AMP ligase
LXM98_05255	COG1535	isochorismatase
LXM98_05255	COG3433	isochorismatase activity
LXM98_05270	COG1132	(ABC) transporter
LXM98_05275	COG1132	(ABC) transporter
LXM98_05280	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LXM98_05290	COG1169	isochorismate synthase
LXM98_05305	COG3739	integral membrane protein
LXM98_05330	COG0302	gtp cyclohydrolase
LXM98_05340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LXM98_05370	COG0308	aminopeptidase N
LXM98_05375	COG0512	Glutamine amidotransferase of anthranilate synthase
LXM98_05390	COG0174	glutamine synthetase
LXM98_05400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LXM98_05435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXM98_05440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LXM98_05445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXM98_05465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LXM98_05470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LXM98_05475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LXM98_05490	COG1960	acyl-CoA dehydrogenase activity
LXM98_05495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LXM98_05500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXM98_05510	COG2223	nitrite transmembrane transporter activity
LXM98_05520	COG0024	Methionine aminopeptidase
LXM98_05525	COG0052	Belongs to the universal ribosomal protein uS2 family
LXM98_05540	COG2207	Transcriptional regulator
LXM98_05565	COG2951	lytic endotransglycosylase activity
LXM98_05570	COG0772	Belongs to the SEDS family
LXM98_05585	COG0842	Transport permease protein
LXM98_05590	COG1131	(ABC) transporter
LXM98_05635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM98_05650	COG4215	(ABC) transporter
LXM98_05655	COG4160	amino acid transport
LXM98_05660	COG4598	ABC transporter
LXM98_05670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LXM98_05675	COG0826	peptidase U32
LXM98_05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXM98_05695	COG1720	tRNA m6t6A37 methyltransferase activity
LXM98_05705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LXM98_05720	COG0642	Histidine kinase
LXM98_05730	COG0494	nUDIX hydrolase
LXM98_05740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXM98_05745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXM98_05750	COG3139	Protein of unknown function (DUF1315)
LXM98_05755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXM98_05760	COG1301	dicarboxylic acid transport
LXM98_05765	COG1960	acyl-CoA dehydrogenase activity
LXM98_05770	COG2819	hydrolase of the alpha beta superfamily
LXM98_05780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LXM98_05790	COG2195	Cleaves the N-terminal amino acid of tripeptides
LXM98_05795	COG1234	tRNA 3'-trailer cleavage
LXM98_05825	COG2363	Small membrane protein
LXM98_05850	COG0513	Belongs to the DEAD box helicase family
LXM98_05860	COG0778	Nitroreductase
LXM98_06070	COG5410	chromosome segregation
LXM98_06190	COG0739	heme binding
LXM98_06260	COG1286	toxin biosynthetic process
LXM98_06285	COG4783	chaperone-mediated protein folding
LXM98_06290	COG1610	YqeY-like protein
LXM98_06390	COG3111	PFAM Bacterial OB fold (BOF) protein
LXM98_06415	COG3243	poly(R)-hydroxyalkanoic acid synthase
LXM98_06420	COG0786	glutamate:sodium symporter activity
LXM98_06430	COG2186	Transcriptional regulator
LXM98_06480	COG0477	Major facilitator Superfamily
LXM98_06510	COG2985	domain, Protein
LXM98_06520	COG2995	paraquat-inducible protein a
LXM98_06525	COG3008	intermembrane lipid transfer
LXM98_06525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LXM98_06535	COG1794	racemase activity, acting on amino acids and derivatives
LXM98_06630	COG0488	(ABC) transporter
LXM98_06635	COG3173	Aminoglycoside phosphotransferase
LXM98_06645	COG2433	Pfam Transposase IS66
LXM98_06660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LXM98_06670	COG3038	cytochrome b561
LXM98_06675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LXM98_06680	COG2252	PERMEase
LXM98_06690	COG2072	flavoprotein involved in K transport
LXM98_06705	COG1741	Belongs to the pirin family
LXM98_06715	COG0527	aspartate kinase activity
LXM98_06725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LXM98_06735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LXM98_06750	COG0667	Aldo Keto reductase
LXM98_06770	COG1765	OsmC-like protein
LXM98_06785	COG0542	response to heat
LXM98_06820	COG2885	chlorophyll binding
LXM98_06830	COG0625	glutathione transferase activity
LXM98_06835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LXM98_06855	COG3634	alkyl hydroperoxide reductase activity
LXM98_06865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LXM98_06875	COG0450	alkyl hydroperoxide reductase
LXM98_06880	COG1643	Atp-dependent helicase
LXM98_06895	COG2814	Major facilitator Superfamily
LXM98_06900	COG3135	benzoate transporter
LXM98_06905	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_06910	COG0633	Ferredoxin
LXM98_06910	COG0543	2 iron, 2 sulfur cluster binding
LXM98_06915	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LXM98_06920	COG4638	Rieske (2fe-2S)
LXM98_06930	COG0583	DNA-binding transcription factor activity
LXM98_06980	COG1570	exodeoxyribonuclease VII activity
LXM98_07010	COG1280	lysine exporter protein (LysE YggA)
LXM98_07015	COG1278	Cold shock
LXM98_07050	COG2814	Major facilitator Superfamily
LXM98_07085	COG0517	IMP dehydrogenase activity
LXM98_07085	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LXM98_07090	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LXM98_07100	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LXM98_07105	COG1137	ATPase activity
LXM98_07110	COG1538	Outer membrane efflux protein
LXM98_07140	COG4122	O-methyltransferase activity
LXM98_07150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LXM98_07165	COG1522	sequence-specific DNA binding
LXM98_07170	COG5006	permease, DMT superfamily
LXM98_07180	COG1560	Kdo2-lipid A biosynthetic process
LXM98_07195	COG2814	Major facilitator Superfamily
LXM98_07215	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXM98_07265	COG0583	DNA-binding transcription factor activity
LXM98_07270	COG1914	H( )-stimulated, divalent metal cation uptake system
LXM98_07290	COG4770	biotin carboxylase activity
LXM98_07295	COG0038	chloride channel
LXM98_07320	COG1309	transcriptional regulator
LXM98_07330	COG1063	alcohol dehydrogenase
LXM98_07345	COG0439	Biotin carboxylase
LXM98_07350	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXM98_07370	COG0864	Transcriptional regulator
LXM98_07380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXM98_07385	COG1116	anion transmembrane transporter activity
LXM98_07410	COG1301	dicarboxylic acid transport
LXM98_07420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXM98_07425	COG2011	ABC-type metal ion transport system permease component
LXM98_07430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXM98_07435	COG1464	Belongs to the NlpA lipoprotein family
LXM98_07440	COG0151	Belongs to the GarS family
LXM98_07445	COG0138	bifunctional purine biosynthesis protein purh
LXM98_07450	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LXM98_07480	COG2308	Evidence 4 Homologs of previously reported genes of
LXM98_07490	COG1305	Transglutaminase-like
LXM98_07500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXM98_07505	COG0305	Participates in initiation and elongation during chromosome replication
LXM98_07530	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LXM98_07540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXM98_07545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXM98_07570	COG0726	polysaccharide deacetylase
LXM98_07570	COG1649	PFAM Uncharacterised BCR, COG1649
LXM98_07575	COG1215	transferase activity, transferring glycosyl groups
LXM98_07580	COG3658	cytochrome
LXM98_07590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXM98_07605	COG0583	DNA-binding transcription factor activity
LXM98_07625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXM98_07630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXM98_07645	COG1960	acyl-CoA dehydrogenase activity
LXM98_07650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXM98_07655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXM98_07680	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LXM98_07685	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LXM98_07695	COG2205	protein histidine kinase activity
LXM98_07700	COG0745	RESPONSE REGULATOR receiver
LXM98_07705	COG0174	glutamine synthetase
LXM98_07725	COG0729	surface antigen
LXM98_07750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXM98_07755	COG2814	Major facilitator Superfamily
LXM98_07770	COG0583	DNA-binding transcription factor activity
LXM98_07785	COG1187	pseudouridine synthase activity
LXM98_07805	COG0802	atpase or kinase
LXM98_07810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LXM98_07820	COG1923	regulation of RNA biosynthetic process
LXM98_07825	COG0697	spore germination
LXM98_07840	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXM98_07850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXM98_07855	COG0519	Catalyzes the synthesis of GMP from XMP
LXM98_07855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXM98_07860	COG4302	ethanolamine ammonia-lyase activity
LXM98_07865	COG4303	Ethanolamine ammonia lyase large subunit
LXM98_07870	COG0531	amino acid
LXM98_07890	COG1454	alcohol dehydrogenase
LXM98_07895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXM98_07905	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LXM98_07925	COG0308	aminopeptidase N
LXM98_07935	COG4221	oxidoreductase activity
LXM98_07945	COG1605	Chorismate mutase
LXM98_07965	COG1309	transcriptional regulator
LXM98_07975	COG0668	transmembrane transport
LXM98_08010	COG4773	Receptor
LXM98_08030	COG0488	(ABC) transporter
LXM98_08035	COG0589	response to stress
LXM98_08060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LXM98_08070	COG3135	benzoate transporter
LXM98_08075	COG1522	sequence-specific DNA binding
LXM98_08085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LXM98_08090	COG0583	DNA-binding transcription factor activity
LXM98_08100	COG0183	Belongs to the thiolase family
LXM98_08110	COG2030	dehydratase
LXM98_08115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXM98_08130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LXM98_08140	COG0824	Thioesterase
LXM98_08145	COG1454	alcohol dehydrogenase
LXM98_08155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXM98_08175	COG0069	glutamate synthase activity
LXM98_08250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LXM98_08255	COG4197	protein conserved in bacteria, prophage-related
LXM98_08510	COG2814	Major facilitator Superfamily
LXM98_08530	COG0511	ligase activity, forming carbon-carbon bonds
LXM98_08550	COG1116	anion transmembrane transporter activity
LXM98_08550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXM98_08555	COG0745	RESPONSE REGULATOR receiver
LXM98_08565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM98_08565	COG2146	nitrite reductase [NAD(P)H] activity
LXM98_08570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM98_08575	COG0243	molybdopterin cofactor binding
LXM98_08585	COG0243	molybdopterin cofactor binding
LXM98_08590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LXM98_08605	COG0521	Mo-molybdopterin cofactor biosynthetic process
LXM98_08605	COG0315	cyclic pyranopterin monophosphate synthase activity
LXM98_08610	COG0303	'Molybdopterin
LXM98_08620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXM98_08625	COG0697	spore germination
LXM98_08645	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LXM98_08650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXM98_08715	COG2204	response regulator
LXM98_08720	COG3852	Histidine kinase
LXM98_08740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LXM98_08745	COG0575	Belongs to the CDS family
LXM98_08780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXM98_08795	COG2137	regulation of response to DNA damage stimulus
LXM98_08805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LXM98_08810	COG1011	Hydrolase
LXM98_08835	COG1522	sequence-specific DNA binding
LXM98_08845	COG1113	amino acid transport
LXM98_08865	COG0659	secondary active sulfate transmembrane transporter activity
LXM98_08870	COG2135	peptidase activity
LXM98_08885	COG3300	MHYT domain
LXM98_08885	COG5001	Diguanylate cyclase
LXM98_08905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXM98_08905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXM98_08905	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LXM98_08910	COG1105	Belongs to the carbohydrate kinase PfkB family
LXM98_08915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LXM98_08915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXM98_08945	COG0024	Methionine aminopeptidase
LXM98_08950	COG0583	DNA-binding transcription factor activity
LXM98_08960	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LXM98_08965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXM98_08970	COG0516	GMP reductase activity
LXM98_08970	COG0517	IMP dehydrogenase activity
LXM98_08995	COG0552	protein localization to endoplasmic reticulum
LXM98_09005	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LXM98_09020	COG4890	Cyd operon protein YbgT
LXM98_09025	COG1294	oxidase, subunit
LXM98_09040	COG1585	Membrane protein implicated in regulation of membrane protease activity
LXM98_09050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXM98_09055	COG4774	siderophore transport
LXM98_09070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXM98_09075	COG0569	domain protein
LXM98_09080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXM98_09110	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LXM98_09115	COG0542	response to heat
LXM98_09140	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXM98_09140	COG1902	pentaerythritol trinitrate reductase activity
LXM98_09185	COG2323	membrane
LXM98_09190	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LXM98_09200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXM98_09205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXM98_09210	COG0183	Belongs to the thiolase family
LXM98_09215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LXM98_09220	COG0596	Alpha beta hydrolase
LXM98_09225	COG2271	Major facilitator Superfamily
LXM98_09230	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LXM98_09235	COG3485	protocatechuate 3,4-dioxygenase
LXM98_09240	COG3485	protocatechuate 3,4-dioxygenase
LXM98_09245	COG0710	3-dehydroquinate dehydratase activity
LXM98_09250	COG3420	alginic acid biosynthetic process
LXM98_09255	COG3659	wide pore channel activity
LXM98_09260	COG4993	Dehydrogenase
LXM98_09270	COG2391	methyltransferase activity
LXM98_09285	COG1414	Transcriptional regulator
LXM98_09290	COG0583	DNA-binding transcription factor activity
LXM98_09295	COG1960	acyl-CoA dehydrogenase activity
LXM98_09320	COG2814	Major facilitator Superfamily
LXM98_09330	COG0154	amidase activity
LXM98_09350	COG4638	Rieske (2fe-2S)
LXM98_09360	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_09370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXM98_09380	COG3733	amine oxidase
LXM98_09390	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_09400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXM98_09405	COG0183	Belongs to the thiolase family
LXM98_09410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXM98_09415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXM98_09425	COG4829	muconolactone delta-isomerase
LXM98_09430	COG4948	Mandelate Racemase Muconate Lactonizing
LXM98_09435	COG0583	DNA-binding transcription factor activity
LXM98_09445	COG2186	Transcriptional regulator
LXM98_09465	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_09485	COG1960	acyl-CoA dehydrogenase activity
LXM98_09490	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_09495	COG3829	transcription factor binding
LXM98_09505	COG3162	membrane
LXM98_09520	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_09535	COG0753	catalase activity
LXM98_09555	COG1846	Transcriptional regulator
LXM98_09560	COG1902	pentaerythritol trinitrate reductase activity
LXM98_09560	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXM98_09570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LXM98_09600	COG1309	transcriptional regulator
LXM98_09610	COG1335	isochorismatase
LXM98_09615	COG0583	DNA-binding transcription factor activity
LXM98_09625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXM98_09625	COG0475	glutathione-regulated potassium exporter activity
LXM98_09635	COG1473	amidohydrolase
LXM98_09645	COG2831	hemolysin activation secretion protein
LXM98_09650	COG3210	domain, Protein
LXM98_09680	COG2188	Transcriptional regulator
LXM98_09695	COG0583	DNA-binding transcription factor activity
LXM98_09725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LXM98_09755	COG1566	PFAM secretion protein HlyD family protein
LXM98_09770	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_09775	COG0129	dihydroxy-acid dehydratase activity
LXM98_09785	COG0583	DNA-binding transcription factor activity
LXM98_09790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXM98_09800	COG2084	Dehydrogenase
LXM98_09805	COG2207	Transcriptional regulator
LXM98_09820	COG1064	alcohol dehydrogenase
LXM98_09830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXM98_09835	COG1120	ATPase activity
LXM98_09855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LXM98_09975	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LXM98_10025	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_10040	COG2207	Transcriptional regulator
LXM98_10055	COG2205	protein histidine kinase activity
LXM98_10060	COG0745	RESPONSE REGULATOR receiver
LXM98_10065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM98_10070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LXM98_10075	COG1538	Outer membrane efflux protein
LXM98_10085	COG2072	flavoprotein involved in K transport
LXM98_10105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXM98_10125	COG3539	Fimbrial protein
LXM98_10155	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LXM98_10165	COG0753	catalase activity
LXM98_10180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXM98_10245	COG1535	isochorismatase
LXM98_10245	COG3433	isochorismatase activity
LXM98_10250	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_10255	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LXM98_10260	COG4149	molybdate abc transporter
LXM98_10265	COG0725	ABC transporter, periplasmic molybdate-binding protein
LXM98_10275	COG4638	Rieske (2fe-2S)
LXM98_10280	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LXM98_10285	COG0543	2 iron, 2 sulfur cluster binding
LXM98_10285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LXM98_10310	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_10325	COG2207	Transcriptional regulator
LXM98_10335	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_10340	COG2610	gluconate transmembrane transporter activity
LXM98_10350	COG0583	DNA-binding transcription factor activity
LXM98_10360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXM98_10365	COG2031	fatty acid transporter
LXM98_10370	COG0183	Belongs to the thiolase family
LXM98_10375	COG0583	DNA-binding transcription factor activity
LXM98_10380	COG0583	DNA-binding transcription factor activity
LXM98_10395	COG1027	Aspartate ammonia-lyase
LXM98_10405	COG0477	Major facilitator Superfamily
LXM98_10425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXM98_10430	COG4521	taurine ABC transporter
LXM98_10445	COG2188	Transcriptional regulator
LXM98_10455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LXM98_10460	COG1733	regulation of RNA biosynthetic process
LXM98_10465	COG2207	Transcriptional regulator
LXM98_10465	COG3708	Transcriptional regulator
LXM98_10480	COG0730	response to heat
LXM98_10495	COG3453	Protein conserved in bacteria
LXM98_10495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXM98_10505	COG3781	membrane
LXM98_10510	COG1063	alcohol dehydrogenase
LXM98_10520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXM98_10525	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXM98_10530	COG0022	dehydrogenase e1 component
LXM98_10535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LXM98_10540	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LXM98_10555	COG3706	GGDEF domain
LXM98_10570	COG0133	tryptophan synthase activity
LXM98_10580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXM98_10615	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LXM98_10640	COG2226	methyltransferase
LXM98_10695	COG0842	Transport permease protein
LXM98_10700	COG0842	Transport permease protein
LXM98_10705	COG1131	(ABC) transporter
LXM98_10720	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXM98_10725	COG4773	Receptor
LXM98_10745	COG0730	response to heat
LXM98_10750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LXM98_10770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LXM98_10785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXM98_10825	COG4264	IucA IucC family
LXM98_10830	COG4264	IucA IucC family
LXM98_10850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LXM98_10865	COG1960	acyl-CoA dehydrogenase activity
LXM98_10870	COG1960	acyl-CoA dehydrogenase activity
LXM98_10875	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LXM98_10880	COG2207	Transcriptional regulator
LXM98_10885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXM98_10890	COG0776	regulation of translation
LXM98_10915	COG0822	iron-sulfur transferase activity
LXM98_10920	COG0316	Belongs to the HesB IscA family
LXM98_10950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LXM98_10980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LXM98_10985	COG0702	epimerase
LXM98_11020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXM98_11030	COG0339	signal peptide processing
LXM98_11080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LXM98_11085	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LXM98_11115	COG0776	regulation of translation
LXM98_11180	COG0084	hydrolase, TatD family'
LXM98_11200	COG1663	tetraacyldisaccharide 4'-kinase activity
LXM98_11205	COG1132	(ABC) transporter
LXM98_11215	COG0811	peptide transport
LXM98_11220	COG1475	DNA binding
LXM98_11225	COG1192	Involved in chromosome partitioning
LXM98_11235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LXM98_11250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXM98_11255	COG0191	fructose-bisphosphate aldolase activity
LXM98_11275	COG0424	maF-like protein
LXM98_11280	COG2850	peptidyl-arginine hydroxylation
LXM98_11290	COG0640	Transcriptional regulator
LXM98_11300	COG3619	membrane
LXM98_11305	COG3122	Protein conserved in bacteria
LXM98_11310	COG1132	(ABC) transporter
LXM98_11330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LXM98_11335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXM98_11345	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LXM98_11345	COG0506	proline dehydrogenase activity
LXM98_11345	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LXM98_11350	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LXM98_11365	COG3698	Phosphodiester glycosidase
LXM98_11375	COG2353	YceI-like domain
LXM98_11385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LXM98_11430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LXM98_11430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LXM98_11455	COG3539	Fimbrial protein
LXM98_11460	COG3121	Chaperone
LXM98_11485	COG0697	spore germination
LXM98_11495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LXM98_11505	COG0583	DNA-binding transcription factor activity
LXM98_11525	COG1309	transcriptional regulator
LXM98_11540	COG1522	sequence-specific DNA binding
LXM98_11555	COG1126	abc transporter atp-binding protein
LXM98_11560	COG0765	amino acid transport
LXM98_11565	COG0765	amino acid transport
LXM98_11595	COG1464	Belongs to the NlpA lipoprotein family
LXM98_11605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXM98_11610	COG2011	ABC-type metal ion transport system permease component
LXM98_11615	COG0012	GTP binding
LXM98_11640	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LXM98_11680	COG0386	Belongs to the glutathione peroxidase family
LXM98_11690	COG0436	Aminotransferase
LXM98_11730	COG3634	alkyl hydroperoxide reductase activity
LXM98_11745	COG0583	DNA-binding transcription factor activity
LXM98_11750	COG0798	PFAM Bile acid sodium symporter
LXM98_11755	COG0640	Transcriptional regulator
LXM98_11770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LXM98_11780	COG0583	DNA-binding transcription factor activity
LXM98_11790	COG1953	Uracil, thiamine, allantoin
LXM98_11800	COG2175	clavaminate synthase activity
LXM98_11805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXM98_11810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LXM98_11815	COG4521	taurine ABC transporter
LXM98_11825	COG0477	Major facilitator Superfamily
LXM98_11850	COG1271	oxidase subunit
LXM98_11855	COG1294	oxidase, subunit
LXM98_11865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXM98_11885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LXM98_11905	COG3052	prosthetic group binding
LXM98_11910	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LXM98_11920	COG2814	Major facilitator Superfamily
LXM98_11940	COG1346	cytolysis
LXM98_11950	COG0583	DNA-binding transcription factor activity
LXM98_11955	COG0625	glutathione transferase activity
LXM98_11960	COG0625	glutathione transferase activity
LXM98_11965	COG0583	DNA-binding transcription factor activity
LXM98_11980	COG1045	serine acetyltransferase
LXM98_11985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXM98_11990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LXM98_12000	COG1280	lysine exporter protein (LysE YggA)
LXM98_12015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXM98_12020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXM98_12025	COG1126	abc transporter atp-binding protein
LXM98_12030	COG0765	amino acid transport
LXM98_12035	COG0765	amino acid transport
LXM98_12055	COG0784	Response regulator, receiver
LXM98_12055	COG2205	protein histidine kinase activity
LXM98_12075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LXM98_12095	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_12145	COG0583	DNA-binding transcription factor activity
LXM98_12170	COG0318	PFAM AMP-dependent synthetase and ligase
LXM98_12175	COG1309	transcriptional regulator
LXM98_12180	COG1960	acyl-CoA dehydrogenase activity
LXM98_12185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXM98_12190	COG1024	Enoyl-CoA hydratase
LXM98_12195	COG4770	biotin carboxylase activity
LXM98_12205	COG0583	DNA-binding transcription factor activity
LXM98_12220	COG1960	acyl-CoA dehydrogenase activity
LXM98_12230	COG2814	Major facilitator Superfamily
LXM98_12240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXM98_12245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXM98_12250	COG2814	Major facilitator Superfamily
LXM98_12255	COG1960	acyl-CoA dehydrogenase activity
LXM98_12260	COG1024	Enoyl-CoA hydratase
LXM98_12265	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_12270	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXM98_12275	COG0183	Belongs to the thiolase family
LXM98_12285	COG2814	Major facilitator Superfamily
LXM98_12295	COG1024	Enoyl-CoA hydratase
LXM98_12310	COG1960	acyl-CoA dehydrogenase activity
LXM98_12315	COG2814	Major facilitator Superfamily
LXM98_12320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXM98_12325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LXM98_12340	COG3842	ATPase activity
LXM98_12345	COG1840	ABC-type Fe3 transport system, periplasmic component
LXM98_12355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXM98_12360	COG1414	Transcriptional regulator
LXM98_12375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LXM98_12425	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_12445	COG0531	amino acid
LXM98_12455	COG1113	amino acid transport
LXM98_12495	COG3209	COG3209 Rhs family protein
LXM98_12525	COG4269	membrane
LXM98_12540	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXM98_12540	COG1902	pentaerythritol trinitrate reductase activity
LXM98_12550	COG3706	GGDEF domain
LXM98_12550	COG5001	Diguanylate cyclase
LXM98_12550	COG2203	Gaf domain
LXM98_12550	COG4251	negative regulation of phosphorylation
LXM98_12560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LXM98_12580	COG4172	Belongs to the ABC transporter superfamily
LXM98_12585	COG4239	(ABC) transporter, permease
LXM98_12590	COG4174	ABC transporter (Permease)
LXM98_12600	COG0741	lytic transglycosylase activity
LXM98_12600	COG0741	lytic transglycosylase activity
LXM98_12600	COG1388	LysM domain
LXM98_12600	COG1388	LysM domain
LXM98_12605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LXM98_12645	COG0583	DNA-binding transcription factor activity
LXM98_12650	COG1279	arginine transmembrane transporter activity
LXM98_12670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXM98_12675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXM98_12680	COG0006	proline dipeptidase activity
LXM98_12720	COG2194	sulfuric ester hydrolase activity
LXM98_12765	COG0739	heme binding
LXM98_13090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LXM98_13115	COG3384	dioxygenase
LXM98_13125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXM98_13130	COG2878	Part of a membrane complex involved in electron transport
LXM98_13135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LXM98_13160	COG0768	penicillin binding
LXM98_13165	COG0742	ribosomal rna small subunit methyltransferase
LXM98_13180	COG0830	nickel cation binding
LXM98_13190	COG0804	urea catabolic process
LXM98_13230	COG1253	flavin adenine dinucleotide binding
LXM98_13235	COG2851	Citrate transporter
LXM98_13285	COG1773	rubredoxin
LXM98_13290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM98_13300	COG0583	DNA-binding transcription factor activity
LXM98_13325	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LXM98_13330	COG4181	ATPase activity
LXM98_13375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LXM98_13395	COG0306	phosphate transporter
LXM98_13405	COG3958	Transketolase
LXM98_13410	COG3959	Transketolase, thiamine diphosphate binding domain
LXM98_13415	COG2271	Major facilitator Superfamily
LXM98_13420	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_13425	COG0583	DNA-binding transcription factor activity
LXM98_13440	COG2223	nitrite transmembrane transporter activity
LXM98_13445	COG2207	Transcriptional regulator
LXM98_13450	COG2066	Belongs to the glutaminase family
LXM98_13455	COG0242	peptide deformylase activity
LXM98_13460	COG0477	Major facilitator Superfamily
LXM98_13470	COG0028	Belongs to the TPP enzyme family
LXM98_13485	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_13490	COG2267	carboxylic ester hydrolase activity
LXM98_13500	COG2271	Major facilitator Superfamily
LXM98_13505	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXM98_13515	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_13535	COG1414	Transcriptional regulator
LXM98_13550	COG1024	Enoyl-CoA hydratase
LXM98_13560	COG1215	transferase activity, transferring glycosyl groups
LXM98_13565	COG0726	polysaccharide deacetylase
LXM98_13565	COG1649	PFAM Uncharacterised BCR, COG1649
LXM98_13575	COG4681	YaeQ
LXM98_13585	COG0523	cobalamin synthesis protein
LXM98_13595	COG1607	acyl-coa hydrolase
LXM98_13605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXM98_13610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXM98_13615	COG1309	transcriptional regulator
LXM98_13640	COG2040	homocysteine
LXM98_13645	COG0531	amino acid
LXM98_13700	COG1595	DNA-templated transcription, initiation
LXM98_13710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LXM98_13715	COG0477	Major facilitator Superfamily
LXM98_13735	COG0084	hydrolase, TatD family'
LXM98_13770	COG0629	single-stranded DNA binding
LXM98_13825	COG0582	viral genome integration into host DNA
LXM98_13855	COG1061	Type III restriction enzyme res subunit
LXM98_13865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LXM98_13870	COG1192	Involved in chromosome partitioning
LXM98_13880	COG1061	Type III restriction enzyme res subunit
LXM98_13970	COG2026	Addiction module toxin, RelE StbE family
LXM98_14120	COG3755	Protein conserved in bacteria
LXM98_14165	COG1484	DNA-dependent DNA replication
LXM98_14255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LXM98_14325	COG0405	Gamma-glutamyltransferase
LXM98_14330	COG2814	Major facilitator Superfamily
LXM98_14340	COG2050	protein possibly involved in aromatic compounds catabolism
LXM98_14355	COG1090	epimerase
LXM98_14375	COG0420	3'-5' exonuclease activity
LXM98_14400	COG0735	belongs to the Fur family
LXM98_14405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LXM98_14425	COG0121	glutamine amidotransferase
LXM98_14440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXM98_14450	COG0210	DNA helicase
LXM98_14455	COG2885	chlorophyll binding
LXM98_14460	COG0204	Acyl-transferase
LXM98_14475	COG2894	cell division
LXM98_14500	COG1280	lysine exporter protein (LysE YggA)
LXM98_14505	COG1674	ftsk spoiiie
LXM98_14505	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LXM98_14510	COG0492	ferredoxin-NADP+ reductase activity
LXM98_14515	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LXM98_14525	COG0456	acetyltransferase
LXM98_14570	COG1981	membrane
LXM98_14585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LXM98_14585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXM98_14605	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_14615	COG0657	acetylesterase activity
LXM98_14625	COG0473	3-isopropylmalate dehydrogenase activity
LXM98_14630	COG0583	DNA-binding transcription factor activity
LXM98_14650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LXM98_14675	COG0564	pseudouridine synthase activity
LXM98_14685	COG0358	DNA primase activity
LXM98_14700	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LXM98_14730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LXM98_14760	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXM98_14770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXM98_14770	COG0352	thiamine-phosphate diphosphorylase activity
LXM98_14770	COG0351	phosphomethylpyrimidine kinase
LXM98_14775	COG1652	LysM domain
LXM98_14800	COG1399	metal-binding, possibly nucleic acid-binding protein
LXM98_14805	COG3101	peptidyl-lysine hydroxylation
LXM98_14810	COG0009	L-threonylcarbamoyladenylate synthase
LXM98_14815	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LXM98_14820	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LXM98_14835	COG4106	trans-aconitate 2-methyltransferase activity
LXM98_14850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXM98_14850	COG2226	methyltransferase
LXM98_14850	COG0596	Alpha beta hydrolase
LXM98_14855	COG1877	trehalose-phosphatase activity
LXM98_14860	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LXM98_14865	COG2223	nitrite transmembrane transporter activity
LXM98_14885	COG1196	nuclear chromosome segregation
LXM98_14895	COG0730	response to heat
LXM98_14910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LXM98_14920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXM98_14980	COG0489	protein tyrosine kinase activity
LXM98_14990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXM98_14990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXM98_15020	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LXM98_15025	COG2081	HI0933 family
LXM98_15035	COG0668	transmembrane transport
LXM98_15055	COG0583	DNA-binding transcription factor activity
LXM98_15075	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXM98_15080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXM98_15110	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LXM98_15150	COG0745	RESPONSE REGULATOR receiver
LXM98_15170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXM98_15180	COG2205	protein histidine kinase activity
LXM98_15250	COG4993	Dehydrogenase
LXM98_15275	COG0384	phenazine biosynthesis protein PhzF
LXM98_15300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXM98_15315	COG0583	DNA-binding transcription factor activity
LXM98_15345	COG0583	DNA-binding transcription factor activity
LXM98_15360	COG0583	DNA-binding transcription factor activity
LXM98_15365	COG1053	succinate dehydrogenase
LXM98_15375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LXM98_15380	COG2814	Major facilitator Superfamily
LXM98_15385	COG1960	acyl-CoA dehydrogenase activity
LXM98_15390	COG0583	DNA-binding transcription factor activity
LXM98_15395	COG1063	alcohol dehydrogenase
LXM98_15425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LXM98_15430	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LXM98_15435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LXM98_15450	COG3667	copper resistance
LXM98_15455	COG2132	Multicopper oxidase
LXM98_15465	COG0561	phosphatase activity
LXM98_15470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LXM98_15495	COG1214	PFAM Peptidase M22, glycoprotease
LXM98_15545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LXM98_15555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LXM98_15560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LXM98_15565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LXM98_15630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXM98_15640	COG1846	Transcriptional regulator
LXM98_15645	COG1764	response to oxidative stress
LXM98_15685	COG0037	tRNA processing
LXM98_15695	COG0248	Ppx GppA phosphatase
LXM98_15725	COG0072	phenylalanine-tRNA ligase activity
LXM98_15770	COG1238	metal cluster binding
LXM98_15775	COG0625	glutathione transferase activity
LXM98_15790	COG0318	PFAM AMP-dependent synthetase and ligase
LXM98_15795	COG3028	Belongs to the UPF0307 family
LXM98_15800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXM98_15820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LXM98_15825	COG0617	tRNA 3'-terminal CCA addition
LXM98_15830	COG1555	photosystem II stabilization
LXM98_15835	COG3956	TIGRFAM MazG family protein
LXM98_15845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXM98_15865	COG5002	protein histidine kinase activity
LXM98_15865	COG2205	protein histidine kinase activity
LXM98_15865	COG0784	Response regulator, receiver
LXM98_15870	COG1024	Enoyl-CoA hydratase
LXM98_15875	COG2084	Dehydrogenase
LXM98_15880	COG3622	Belongs to the hyi family
LXM98_15910	COG0697	spore germination
LXM98_15920	COG2814	Major facilitator Superfamily
LXM98_15925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXM98_15935	COG0583	DNA-binding transcription factor activity
LXM98_15945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LXM98_15960	COG0084	hydrolase, TatD family'
LXM98_15975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LXM98_16005	COG0440	acetolactate synthase activity
LXM98_16010	COG0028	Belongs to the TPP enzyme family
LXM98_16035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM98_16040	COG1136	(ABC) transporter
LXM98_16040	COG0577	efflux transmembrane transporter activity
LXM98_16045	COG1538	Outer membrane efflux protein
LXM98_16060	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LXM98_16065	COG1162	GTPase activity
LXM98_16075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LXM98_16095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXM98_16100	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_16140	COG2986	histidine ammonia-lyase
LXM98_16155	COG0318	PFAM AMP-dependent synthetase and ligase
LXM98_16165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXM98_16210	COG1426	Protein conserved in bacteria
LXM98_16245	COG0793	Belongs to the peptidase S41A family
LXM98_16260	COG2267	carboxylic ester hydrolase activity
LXM98_16270	COG1012	belongs to the aldehyde dehydrogenase family
LXM98_16275	COG3265	gluconokinase activity
LXM98_16285	COG0800	Aldolase
LXM98_16295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LXM98_16300	COG0280	phosphate acetyltransferase
LXM98_16300	COG0857	belongs to the CobB CobQ family
LXM98_16305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LXM98_16305	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LXM98_16325	COG0740	serine-type endopeptidase activity
LXM98_16335	COG4774	siderophore transport
LXM98_16345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXM98_16355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXM98_16355	COG2813	Specifically methylates the guanine in position
LXM98_16455	COG0788	formyltetrahydrofolate deformylase activity
LXM98_16480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXM98_16480	COG4651	solute:proton antiporter activity
LXM98_16500	COG0724	RNA recognition motif
LXM98_16505	COG0210	DNA helicase
LXM98_16530	COG1733	regulation of RNA biosynthetic process
LXM98_16540	COG2900	Belongs to the SlyX family
LXM98_16545	COG0488	(ABC) transporter
LXM98_16550	COG1280	lysine exporter protein (LysE YggA)
LXM98_16555	COG1560	Kdo2-lipid A biosynthetic process
LXM98_16565	COG1301	dicarboxylic acid transport
LXM98_16620	COG0473	3-isopropylmalate dehydrogenase activity
LXM98_16655	COG3328	transposase activity
LXM98_16690	COG0583	DNA-binding transcription factor activity
LXM98_16700	COG0625	glutathione transferase activity
LXM98_16705	COG2378	regulation of single-species biofilm formation
LXM98_16710	COG0546	phosphoglycolate phosphatase activity
LXM98_16720	COG1530	ribonuclease E activity
LXM98_16725	COG0318	PFAM AMP-dependent synthetase and ligase
LXM98_16740	COG0583	DNA-binding transcription factor activity
LXM98_16745	COG4221	oxidoreductase activity
LXM98_16750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXM98_16760	COG0534	Mate efflux family protein
LXM98_16775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LXM98_16815	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LXM98_16820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXM98_16835	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LXM98_16845	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LXM98_16845	COG0644	oxidoreductase
LXM98_16850	COG0425	Belongs to the sulfur carrier protein TusA family
LXM98_16855	COG4535	Mg2 and Co2 transporter CorC
LXM98_16865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXM98_16885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LXM98_16890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXM98_16890	COG0475	glutathione-regulated potassium exporter activity
LXM98_16895	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LXM98_16905	COG0484	heat shock protein binding
LXM98_16910	COG0789	Transcriptional regulator
LXM98_16915	COG0598	Magnesium transport protein CorA
LXM98_16930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXM98_16935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXM98_16940	COG1074	ATP-dependent DNA helicase activity
LXM98_16945	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LXM98_16965	COG2226	methyltransferase
LXM98_16980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXM98_16985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LXM98_17000	COG2111	Na H antiporter
LXM98_17000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXM98_17005	COG1006	Multisubunit Na H antiporter MnhC subunit
LXM98_17010	COG0651	ATP synthesis coupled electron transport
LXM98_17015	COG1863	multisubunit Na H antiporter MnhE subunit
LXM98_17020	COG2212	antiporter activity
LXM98_17025	COG1320	monovalent cation:proton antiporter activity
LXM98_17040	COG0195	Participates in both transcription termination and antitermination
LXM98_17090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LXM98_17095	COG0237	dephospho-CoA kinase activity
LXM98_17105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXM98_17120	COG0497	DNA recombination
LXM98_17130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LXM98_17160	COG2169	Transcriptional regulator
LXM98_17160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LXM98_17165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LXM98_17230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LXM98_17245	COG0326	Molecular chaperone. Has ATPase activity
LXM98_17260	COG2056	Na+-H+ antiporter family
LXM98_17265	COG0596	Alpha beta hydrolase
LXM98_17360	COG0546	phosphoglycolate phosphatase activity
LXM98_17365	COG1716	ATPase activity
LXM98_17410	COG0181	hydroxymethylbilane synthase activity
LXM98_17420	COG3275	phosphorelay sensor kinase activity
LXM98_17440	COG1538	Outer membrane efflux protein
LXM98_17445	COG0697	spore germination
LXM98_17470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LXM98_17475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXM98_17480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXM98_17485	COG0772	Belongs to the SEDS family
LXM98_17510	COG4974	Belongs to the 'phage' integrase family
LXM98_17515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXM98_17525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LXM98_17535	COG2197	response regulator
LXM98_17550	COG0793	Belongs to the peptidase S41A family
LXM98_17555	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LXM98_17560	COG0795	lipopolysaccharide-transporting ATPase activity
LXM98_17600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXM98_17600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXM98_17610	COG0004	ammonium transporteR
LXM98_17615	COG0347	Belongs to the P(II) protein family
LXM98_17675	COG0659	secondary active sulfate transmembrane transporter activity
LXM98_17680	COG0589	response to stress
LXM98_17715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXM98_17725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LXM98_17745	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LXM98_17760	COG0318	PFAM AMP-dependent synthetase and ligase
LXM98_17770	COG0477	Major facilitator Superfamily
LXM98_17775	COG2860	membrane
LXM98_17785	COG1253	flavin adenine dinucleotide binding
LXM98_17805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXM98_17845	COG0655	NAD(P)H dehydrogenase (quinone) activity
LXM98_17855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXM98_17925	COG0758	DNA mediated transformation
LXM98_17935	COG0697	spore germination
LXM98_17940	COG1309	transcriptional regulator
LXM98_17955	COG0386	Belongs to the glutathione peroxidase family
LXM98_18020	COG1121	(ABC) transporter
LXM98_18025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXM98_18030	COG1280	lysine exporter protein (LysE YggA)
LXM98_18035	COG2837	iron assimilation
LXM98_18045	COG0281	malic enzyme
LXM98_18090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXM98_18090	COG0519	Catalyzes the synthesis of GMP from XMP
LXM98_18095	COG4399	Belongs to the UPF0754 family
LXM98_18100	COG2259	Doxx family
LXM98_18105	COG0586	Pfam SNARE associated Golgi protein
LXM98_18120	COG1192	Involved in chromosome partitioning
LXM98_18130	COG0271	Belongs to the BolA IbaG family
LXM98_18150	COG2267	carboxylic ester hydrolase activity
LXM98_18170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXM98_18170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LXM98_18170	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LXM98_18170	COG3321	synthase
LXM98_18175	COG1960	acyl-CoA dehydrogenase activity
LXM98_18185	COG2197	response regulator
LXM98_18195	COG3916	Acyl-homoserine-lactone synthase
LXM98_18200	COG0477	Major facilitator Superfamily
LXM98_18205	COG1024	Enoyl-CoA hydratase
LXM98_18210	COG1024	Enoyl-CoA hydratase
LXM98_18215	COG1960	acyl-CoA dehydrogenase activity
LXM98_18220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXM98_18240	COG1113	amino acid transport
LXM98_18245	COG1113	amino acid transport
LXM98_18250	COG0251	oxidation-reduction process
LXM98_18290	COG0564	pseudouridine synthase activity
LXM98_18350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LXM98_18365	COG1802	Transcriptional regulator
LXM98_18375	COG1448	Aminotransferase
LXM98_18380	COG0277	FAD linked oxidase domain protein
LXM98_18390	COG2186	Transcriptional regulator
LXM98_18400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXM98_18405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXM98_18420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LXM98_18425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LXM98_18430	COG1216	Glycosyl transferase, family 2
LXM98_18460	COG2089	acid synthase
LXM98_18475	COG1083	cytidylyl-transferase
LXM98_18480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LXM98_18485	COG1086	Polysaccharide biosynthesis protein
LXM98_18490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LXM98_18495	COG1596	polysaccharide export
LXM98_18520	COG0728	peptidoglycan biosynthetic process
LXM98_18525	COG3023	N-Acetylmuramoyl-L-alanine amidase
LXM98_18585	COG0546	phosphoglycolate phosphatase activity
LXM98_18590	COG1028	Short-chain dehydrogenase reductase Sdr
LXM98_18610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXM98_18615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXM98_18620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXM98_18625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXM98_18630	COG1116	anion transmembrane transporter activity
LXM98_18635	COG1309	transcriptional regulator
LXM98_18640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LXM98_18650	COG0196	riboflavin kinase activity
LXM98_18655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LXM98_18665	COG1047	Peptidyl-prolyl cis-trans
LXM98_18705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LXM98_18710	COG0657	acetylesterase activity
LXM98_18730	COG0583	DNA-binding transcription factor activity
LXM98_18760	COG2951	lytic endotransglycosylase activity
LXM98_18765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LXM98_18780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LXM98_18790	COG0671	phosphoesterase, PA-phosphatase related
LXM98_18795	COG0861	Integral membrane protein TerC family
LXM98_18805	COG0754	glutathionylspermidine amidase activity
LXM98_18815	COG0402	S-adenosylhomocysteine deaminase activity
LXM98_18830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXM98_18835	COG1230	cation diffusion facilitator family transporter
LXM98_18850	COG0706	membrane insertase activity
LXM98_18885	COG4683	PFAM Phage derived protein Gp49-like (DUF891)