locus-tag	class	description
L2Z37_00005	COG3781	membrane
L2Z37_00010	COG1063	alcohol dehydrogenase
L2Z37_00020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z37_00025	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z37_00030	COG0022	dehydrogenase e1 component
L2Z37_00035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z37_00040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z37_00055	COG3706	GGDEF domain
L2Z37_00070	COG0133	tryptophan synthase activity
L2Z37_00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z37_00115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z37_00140	COG2226	methyltransferase
L2Z37_00195	COG0842	Transport permease protein
L2Z37_00200	COG0842	Transport permease protein
L2Z37_00205	COG1131	(ABC) transporter
L2Z37_00220	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z37_00225	COG4773	Receptor
L2Z37_00245	COG0730	response to heat
L2Z37_00250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z37_00270	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z37_00285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z37_00325	COG4264	IucA IucC family
L2Z37_00330	COG4264	IucA IucC family
L2Z37_00350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z37_00365	COG1960	acyl-CoA dehydrogenase activity
L2Z37_00370	COG1960	acyl-CoA dehydrogenase activity
L2Z37_00375	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z37_00380	COG2207	Transcriptional regulator
L2Z37_00385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z37_00390	COG0776	regulation of translation
L2Z37_00415	COG0822	iron-sulfur transferase activity
L2Z37_00420	COG0316	Belongs to the HesB IscA family
L2Z37_00450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z37_00470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z37_00475	COG0702	epimerase
L2Z37_00510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z37_00520	COG0339	signal peptide processing
L2Z37_00570	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z37_00575	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z37_00605	COG0776	regulation of translation
L2Z37_00670	COG0084	hydrolase, TatD family'
L2Z37_00690	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z37_00695	COG1132	(ABC) transporter
L2Z37_00705	COG0811	peptide transport
L2Z37_00710	COG1475	DNA binding
L2Z37_00715	COG1192	Involved in chromosome partitioning
L2Z37_00725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z37_00740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z37_00745	COG0191	fructose-bisphosphate aldolase activity
L2Z37_00765	COG0424	maF-like protein
L2Z37_00770	COG2850	peptidyl-arginine hydroxylation
L2Z37_00780	COG0640	Transcriptional regulator
L2Z37_00790	COG3619	membrane
L2Z37_00795	COG3122	Protein conserved in bacteria
L2Z37_00800	COG1132	(ABC) transporter
L2Z37_00820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z37_00825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z37_00835	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z37_00835	COG0506	proline dehydrogenase activity
L2Z37_00835	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z37_00840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z37_00855	COG3698	Phosphodiester glycosidase
L2Z37_00865	COG2353	YceI-like domain
L2Z37_00875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z37_00920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z37_00920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z37_00950	COG3539	Fimbrial protein
L2Z37_00955	COG3121	Chaperone
L2Z37_00980	COG0697	spore germination
L2Z37_00990	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z37_01000	COG0583	DNA-binding transcription factor activity
L2Z37_01020	COG1309	transcriptional regulator
L2Z37_01035	COG1522	sequence-specific DNA binding
L2Z37_01045	COG1126	abc transporter atp-binding protein
L2Z37_01050	COG0765	amino acid transport
L2Z37_01055	COG0765	amino acid transport
L2Z37_01085	COG1464	Belongs to the NlpA lipoprotein family
L2Z37_01095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z37_01100	COG2011	ABC-type metal ion transport system permease component
L2Z37_01105	COG0012	GTP binding
L2Z37_01130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z37_01170	COG0386	Belongs to the glutathione peroxidase family
L2Z37_01180	COG0436	Aminotransferase
L2Z37_01220	COG3634	alkyl hydroperoxide reductase activity
L2Z37_01235	COG0583	DNA-binding transcription factor activity
L2Z37_01240	COG0798	PFAM Bile acid sodium symporter
L2Z37_01245	COG0640	Transcriptional regulator
L2Z37_01260	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z37_01270	COG0583	DNA-binding transcription factor activity
L2Z37_01280	COG1953	Uracil, thiamine, allantoin
L2Z37_01290	COG2175	clavaminate synthase activity
L2Z37_01295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z37_01300	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z37_01305	COG4521	taurine ABC transporter
L2Z37_01315	COG0477	Major facilitator Superfamily
L2Z37_01335	COG1271	oxidase subunit
L2Z37_01340	COG1294	oxidase, subunit
L2Z37_01350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z37_01370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z37_01390	COG3052	prosthetic group binding
L2Z37_01395	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z37_01405	COG2814	Major facilitator Superfamily
L2Z37_01425	COG1346	cytolysis
L2Z37_01435	COG0583	DNA-binding transcription factor activity
L2Z37_01440	COG0625	glutathione transferase activity
L2Z37_01445	COG0625	glutathione transferase activity
L2Z37_01450	COG0583	DNA-binding transcription factor activity
L2Z37_01465	COG1045	serine acetyltransferase
L2Z37_01470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z37_01475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z37_01485	COG1280	lysine exporter protein (LysE YggA)
L2Z37_01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z37_01505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z37_01510	COG1126	abc transporter atp-binding protein
L2Z37_01515	COG0765	amino acid transport
L2Z37_01520	COG0765	amino acid transport
L2Z37_01540	COG0784	Response regulator, receiver
L2Z37_01540	COG2205	protein histidine kinase activity
L2Z37_01560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z37_01585	COG2826	transposase and inactivated derivatives, IS30 family
L2Z37_01645	COG0583	DNA-binding transcription factor activity
L2Z37_01665	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z37_01670	COG1309	transcriptional regulator
L2Z37_01675	COG1960	acyl-CoA dehydrogenase activity
L2Z37_01680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z37_01685	COG1024	Enoyl-CoA hydratase
L2Z37_01690	COG4770	biotin carboxylase activity
L2Z37_01700	COG0583	DNA-binding transcription factor activity
L2Z37_01715	COG1960	acyl-CoA dehydrogenase activity
L2Z37_01725	COG2814	Major facilitator Superfamily
L2Z37_01735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z37_01740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z37_01745	COG2814	Major facilitator Superfamily
L2Z37_01750	COG1960	acyl-CoA dehydrogenase activity
L2Z37_01755	COG1024	Enoyl-CoA hydratase
L2Z37_01760	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_01765	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z37_01770	COG0183	Belongs to the thiolase family
L2Z37_01780	COG2814	Major facilitator Superfamily
L2Z37_01790	COG1024	Enoyl-CoA hydratase
L2Z37_01805	COG1960	acyl-CoA dehydrogenase activity
L2Z37_01810	COG2814	Major facilitator Superfamily
L2Z37_01815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z37_01820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z37_01835	COG3842	ATPase activity
L2Z37_01840	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z37_01850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z37_01855	COG1414	Transcriptional regulator
L2Z37_01865	COG0583	DNA-binding transcription factor activity
L2Z37_01870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z37_01875	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_01975	COG4397	Mu-like prophage major head subunit gpT
L2Z37_01990	COG5005	Phage virion morphogenesis
L2Z37_01995	COG2369	cell adhesion
L2Z37_02000	COG4383	Mu-like prophage protein gp29
L2Z37_02015	COG4373	Mu-like prophage FluMu protein gp28
L2Z37_02050	COG0681	Belongs to the peptidase S26 family
L2Z37_02080	COG3267	Type II secretory pathway component ExeA
L2Z37_02080	COG3409	Peptidoglycan-binding domain 1 protein
L2Z37_02115	COG0776	regulation of translation
L2Z37_02165	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_02170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z37_02175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z37_02180	COG2267	carboxylic ester hydrolase activity
L2Z37_02200	COG3038	cytochrome b561
L2Z37_02205	COG0753	catalase activity
L2Z37_02240	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z37_02250	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z37_02255	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z37_02260	COG0183	Belongs to the thiolase family
L2Z37_02265	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z37_02270	COG1024	Enoyl-CoA hydratase
L2Z37_02295	COG1309	transcriptional regulator
L2Z37_02315	COG0038	chloride channel
L2Z37_02320	COG4770	biotin carboxylase activity
L2Z37_02340	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z37_02345	COG0583	DNA-binding transcription factor activity
L2Z37_02405	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z37_02425	COG2814	Major facilitator Superfamily
L2Z37_02440	COG1560	Kdo2-lipid A biosynthetic process
L2Z37_02450	COG5006	permease, DMT superfamily
L2Z37_02455	COG1522	sequence-specific DNA binding
L2Z37_02470	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z37_02480	COG4122	O-methyltransferase activity
L2Z37_02510	COG1538	Outer membrane efflux protein
L2Z37_02515	COG1137	ATPase activity
L2Z37_02520	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z37_02530	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z37_02535	COG0517	IMP dehydrogenase activity
L2Z37_02535	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z37_02570	COG2814	Major facilitator Superfamily
L2Z37_02605	COG1278	Cold shock
L2Z37_02610	COG1280	lysine exporter protein (LysE YggA)
L2Z37_02640	COG1570	exodeoxyribonuclease VII activity
L2Z37_02690	COG0583	DNA-binding transcription factor activity
L2Z37_02700	COG4638	Rieske (2fe-2S)
L2Z37_02705	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z37_02710	COG0633	Ferredoxin
L2Z37_02710	COG0543	2 iron, 2 sulfur cluster binding
L2Z37_02715	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_02720	COG3135	benzoate transporter
L2Z37_02725	COG2814	Major facilitator Superfamily
L2Z37_02740	COG1643	Atp-dependent helicase
L2Z37_02745	COG0450	alkyl hydroperoxide reductase
L2Z37_02755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z37_02765	COG3634	alkyl hydroperoxide reductase activity
L2Z37_02785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z37_02790	COG0625	glutathione transferase activity
L2Z37_02800	COG2885	chlorophyll binding
L2Z37_02835	COG0542	response to heat
L2Z37_02850	COG1765	OsmC-like protein
L2Z37_02870	COG0667	Aldo Keto reductase
L2Z37_02885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z37_02895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z37_02905	COG0527	aspartate kinase activity
L2Z37_02915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z37_02925	COG3038	cytochrome b561
L2Z37_02930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z37_02935	COG2252	PERMEase
L2Z37_02945	COG2072	flavoprotein involved in K transport
L2Z37_02960	COG1741	Belongs to the pirin family
L2Z37_02965	COG1309	transcriptional regulator
L2Z37_02975	COG0300	oxidoreductase activity
L2Z37_03015	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_03035	COG0531	amino acid
L2Z37_03045	COG1113	amino acid transport
L2Z37_03085	COG3209	COG3209 Rhs family protein
L2Z37_03115	COG4269	membrane
L2Z37_03130	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z37_03130	COG1902	pentaerythritol trinitrate reductase activity
L2Z37_03140	COG2203	Gaf domain
L2Z37_03140	COG3706	GGDEF domain
L2Z37_03140	COG5001	Diguanylate cyclase
L2Z37_03140	COG4251	negative regulation of phosphorylation
L2Z37_03150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z37_03170	COG4172	Belongs to the ABC transporter superfamily
L2Z37_03175	COG4239	(ABC) transporter, permease
L2Z37_03180	COG4174	ABC transporter (Permease)
L2Z37_03185	COG4166	transmembrane transport
L2Z37_03190	COG0741	lytic transglycosylase activity
L2Z37_03190	COG1388	LysM domain
L2Z37_03190	COG1388	LysM domain
L2Z37_03190	COG0741	lytic transglycosylase activity
L2Z37_03195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z37_03235	COG0583	DNA-binding transcription factor activity
L2Z37_03240	COG1279	arginine transmembrane transporter activity
L2Z37_03260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z37_03265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z37_03270	COG0006	proline dipeptidase activity
L2Z37_03355	COG0739	heme binding
L2Z37_03355	COG0741	lytic transglycosylase activity
L2Z37_03355	COG1196	nuclear chromosome segregation
L2Z37_03415	COG4695	Portal protein
L2Z37_03515	COG0305	Participates in initiation and elongation during chromosome replication
L2Z37_03530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z37_03635	COG0739	heme binding
L2Z37_03960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z37_03985	COG3384	dioxygenase
L2Z37_03995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z37_04000	COG2878	Part of a membrane complex involved in electron transport
L2Z37_04005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z37_04030	COG0768	penicillin binding
L2Z37_04035	COG0742	ribosomal rna small subunit methyltransferase
L2Z37_04050	COG0830	nickel cation binding
L2Z37_04060	COG0804	urea catabolic process
L2Z37_04100	COG1253	flavin adenine dinucleotide binding
L2Z37_04105	COG2851	Citrate transporter
L2Z37_04155	COG1773	rubredoxin
L2Z37_04160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z37_04170	COG0583	DNA-binding transcription factor activity
L2Z37_04195	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z37_04200	COG4181	ATPase activity
L2Z37_04245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z37_04265	COG0306	phosphate transporter
L2Z37_04275	COG3958	Transketolase
L2Z37_04280	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z37_04285	COG2271	Major facilitator Superfamily
L2Z37_04290	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_04295	COG0583	DNA-binding transcription factor activity
L2Z37_04310	COG2223	nitrite transmembrane transporter activity
L2Z37_04315	COG2207	Transcriptional regulator
L2Z37_04320	COG2066	Belongs to the glutaminase family
L2Z37_04325	COG0242	peptide deformylase activity
L2Z37_04330	COG0477	Major facilitator Superfamily
L2Z37_04340	COG0028	Belongs to the TPP enzyme family
L2Z37_04355	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_04360	COG2267	carboxylic ester hydrolase activity
L2Z37_04370	COG2271	Major facilitator Superfamily
L2Z37_04385	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_04405	COG1414	Transcriptional regulator
L2Z37_04420	COG1024	Enoyl-CoA hydratase
L2Z37_04430	COG1215	transferase activity, transferring glycosyl groups
L2Z37_04435	COG0726	polysaccharide deacetylase
L2Z37_04435	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z37_04445	COG4681	YaeQ
L2Z37_04455	COG0523	cobalamin synthesis protein
L2Z37_04465	COG1607	acyl-coa hydrolase
L2Z37_04475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z37_04480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z37_04485	COG1309	transcriptional regulator
L2Z37_04510	COG2040	homocysteine
L2Z37_04515	COG0531	amino acid
L2Z37_04570	COG1595	DNA-templated transcription, initiation
L2Z37_04580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z37_04585	COG0477	Major facilitator Superfamily
L2Z37_04605	COG0084	hydrolase, TatD family'
L2Z37_04640	COG0629	single-stranded DNA binding
L2Z37_04695	COG0582	viral genome integration into host DNA
L2Z37_04785	COG0592	DNA-directed DNA polymerase activity
L2Z37_04825	COG2026	Addiction module toxin, RelE StbE family
L2Z37_04975	COG3755	Protein conserved in bacteria
L2Z37_05025	COG1484	DNA-dependent DNA replication
L2Z37_05115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z37_05185	COG0405	Gamma-glutamyltransferase
L2Z37_05190	COG2814	Major facilitator Superfamily
L2Z37_05200	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z37_05215	COG1090	epimerase
L2Z37_05235	COG0420	3'-5' exonuclease activity
L2Z37_05260	COG0735	belongs to the Fur family
L2Z37_05265	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z37_05285	COG0121	glutamine amidotransferase
L2Z37_05300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z37_05310	COG0210	DNA helicase
L2Z37_05315	COG2885	chlorophyll binding
L2Z37_05320	COG0204	Acyl-transferase
L2Z37_05335	COG2894	cell division
L2Z37_05360	COG1280	lysine exporter protein (LysE YggA)
L2Z37_05365	COG1674	ftsk spoiiie
L2Z37_05365	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z37_05370	COG0492	ferredoxin-NADP+ reductase activity
L2Z37_05375	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z37_05385	COG0456	acetyltransferase
L2Z37_05430	COG1981	membrane
L2Z37_05445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z37_05445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z37_05465	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_05475	COG0657	acetylesterase activity
L2Z37_05485	COG0473	3-isopropylmalate dehydrogenase activity
L2Z37_05490	COG0583	DNA-binding transcription factor activity
L2Z37_05510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z37_05535	COG0564	pseudouridine synthase activity
L2Z37_05545	COG0358	DNA primase activity
L2Z37_05560	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z37_05590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z37_05620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z37_05630	COG0351	phosphomethylpyrimidine kinase
L2Z37_05630	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z37_05630	COG0352	thiamine-phosphate diphosphorylase activity
L2Z37_05635	COG1652	LysM domain
L2Z37_05660	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z37_05665	COG3101	peptidyl-lysine hydroxylation
L2Z37_05670	COG0009	L-threonylcarbamoyladenylate synthase
L2Z37_05675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z37_05680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z37_05695	COG4106	trans-aconitate 2-methyltransferase activity
L2Z37_05710	COG0596	Alpha beta hydrolase
L2Z37_05710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z37_05710	COG2226	methyltransferase
L2Z37_05715	COG1877	trehalose-phosphatase activity
L2Z37_05720	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z37_05725	COG2223	nitrite transmembrane transporter activity
L2Z37_05745	COG1196	nuclear chromosome segregation
L2Z37_05755	COG0730	response to heat
L2Z37_05770	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z37_05780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z37_05830	COG0489	protein tyrosine kinase activity
L2Z37_05840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z37_05840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z37_05870	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z37_05875	COG2081	HI0933 family
L2Z37_05885	COG0668	transmembrane transport
L2Z37_05905	COG0583	DNA-binding transcription factor activity
L2Z37_05925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z37_05930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z37_05960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z37_06000	COG0745	RESPONSE REGULATOR receiver
L2Z37_06020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z37_06030	COG2205	protein histidine kinase activity
L2Z37_06095	COG4993	Dehydrogenase
L2Z37_06115	COG0384	phenazine biosynthesis protein PhzF
L2Z37_06140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z37_06155	COG0583	DNA-binding transcription factor activity
L2Z37_06185	COG0583	DNA-binding transcription factor activity
L2Z37_06200	COG0583	DNA-binding transcription factor activity
L2Z37_06205	COG1053	succinate dehydrogenase
L2Z37_06215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z37_06220	COG2814	Major facilitator Superfamily
L2Z37_06225	COG1960	acyl-CoA dehydrogenase activity
L2Z37_06230	COG0583	DNA-binding transcription factor activity
L2Z37_06235	COG1063	alcohol dehydrogenase
L2Z37_06265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z37_06270	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z37_06275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z37_06290	COG3667	copper resistance
L2Z37_06295	COG2132	Multicopper oxidase
L2Z37_06305	COG0561	phosphatase activity
L2Z37_06310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z37_06335	COG1214	PFAM Peptidase M22, glycoprotease
L2Z37_06385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z37_06395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z37_06400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z37_06405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z37_06465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z37_06475	COG1846	Transcriptional regulator
L2Z37_06480	COG1764	response to oxidative stress
L2Z37_06520	COG0037	tRNA processing
L2Z37_06530	COG0248	Ppx GppA phosphatase
L2Z37_06560	COG0072	phenylalanine-tRNA ligase activity
L2Z37_06605	COG1238	metal cluster binding
L2Z37_06610	COG0625	glutathione transferase activity
L2Z37_06625	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z37_06630	COG3028	Belongs to the UPF0307 family
L2Z37_06635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z37_06655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z37_06660	COG0617	tRNA 3'-terminal CCA addition
L2Z37_06665	COG1555	photosystem II stabilization
L2Z37_06670	COG3956	TIGRFAM MazG family protein
L2Z37_06680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z37_06700	COG0784	Response regulator, receiver
L2Z37_06700	COG2205	protein histidine kinase activity
L2Z37_06700	COG5002	protein histidine kinase activity
L2Z37_06705	COG1024	Enoyl-CoA hydratase
L2Z37_06710	COG2084	Dehydrogenase
L2Z37_06715	COG3622	Belongs to the hyi family
L2Z37_06745	COG0697	spore germination
L2Z37_06755	COG2814	Major facilitator Superfamily
L2Z37_06760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z37_06770	COG0583	DNA-binding transcription factor activity
L2Z37_06780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z37_06795	COG0084	hydrolase, TatD family'
L2Z37_06810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z37_06840	COG0440	acetolactate synthase activity
L2Z37_06845	COG0028	Belongs to the TPP enzyme family
L2Z37_06870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z37_06875	COG0577	efflux transmembrane transporter activity
L2Z37_06875	COG1136	(ABC) transporter
L2Z37_06880	COG1538	Outer membrane efflux protein
L2Z37_06895	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z37_06900	COG1162	GTPase activity
L2Z37_06910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z37_06930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z37_06935	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_06975	COG2986	histidine ammonia-lyase
L2Z37_06990	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z37_07000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z37_07045	COG1426	Protein conserved in bacteria
L2Z37_07080	COG0793	Belongs to the peptidase S41A family
L2Z37_07095	COG2267	carboxylic ester hydrolase activity
L2Z37_07105	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_07110	COG3265	gluconokinase activity
L2Z37_07120	COG0800	Aldolase
L2Z37_07130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z37_07135	COG0280	phosphate acetyltransferase
L2Z37_07135	COG0857	belongs to the CobB CobQ family
L2Z37_07140	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z37_07140	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z37_07160	COG0740	serine-type endopeptidase activity
L2Z37_07170	COG4774	siderophore transport
L2Z37_07180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z37_07190	COG2813	Specifically methylates the guanine in position
L2Z37_07190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z37_07290	COG0788	formyltetrahydrofolate deformylase activity
L2Z37_07315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z37_07315	COG4651	solute:proton antiporter activity
L2Z37_07335	COG0724	RNA recognition motif
L2Z37_07340	COG0210	DNA helicase
L2Z37_07365	COG1733	regulation of RNA biosynthetic process
L2Z37_07375	COG2900	Belongs to the SlyX family
L2Z37_07380	COG0488	(ABC) transporter
L2Z37_07385	COG1280	lysine exporter protein (LysE YggA)
L2Z37_07390	COG1560	Kdo2-lipid A biosynthetic process
L2Z37_07400	COG1301	dicarboxylic acid transport
L2Z37_07455	COG0473	3-isopropylmalate dehydrogenase activity
L2Z37_07520	COG0583	DNA-binding transcription factor activity
L2Z37_07530	COG0625	glutathione transferase activity
L2Z37_07535	COG2378	regulation of single-species biofilm formation
L2Z37_07540	COG0546	phosphoglycolate phosphatase activity
L2Z37_07550	COG1530	ribonuclease E activity
L2Z37_07555	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z37_07570	COG0583	DNA-binding transcription factor activity
L2Z37_07575	COG4221	oxidoreductase activity
L2Z37_07580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z37_07590	COG0534	Mate efflux family protein
L2Z37_07605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z37_07645	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z37_07650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z37_07665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z37_07675	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z37_07675	COG0644	oxidoreductase
L2Z37_07680	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z37_07685	COG4535	Mg2 and Co2 transporter CorC
L2Z37_07695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z37_07715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z37_07720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z37_07720	COG0475	glutathione-regulated potassium exporter activity
L2Z37_07725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z37_07735	COG0484	heat shock protein binding
L2Z37_07740	COG0789	Transcriptional regulator
L2Z37_07745	COG0598	Magnesium transport protein CorA
L2Z37_07760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z37_07765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z37_07770	COG1074	ATP-dependent DNA helicase activity
L2Z37_07775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z37_07795	COG2226	methyltransferase
L2Z37_07810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z37_07815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z37_07830	COG2111	Na H antiporter
L2Z37_07830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z37_07835	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z37_07840	COG0651	ATP synthesis coupled electron transport
L2Z37_07845	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z37_07850	COG2212	antiporter activity
L2Z37_07855	COG1320	monovalent cation:proton antiporter activity
L2Z37_07870	COG0195	Participates in both transcription termination and antitermination
L2Z37_07920	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z37_07925	COG0237	dephospho-CoA kinase activity
L2Z37_07935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z37_07950	COG0497	DNA recombination
L2Z37_07960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z37_07990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z37_07990	COG2169	Transcriptional regulator
L2Z37_07995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z37_08060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z37_08075	COG0326	Molecular chaperone. Has ATPase activity
L2Z37_08090	COG2056	Na+-H+ antiporter family
L2Z37_08095	COG0596	Alpha beta hydrolase
L2Z37_08190	COG0546	phosphoglycolate phosphatase activity
L2Z37_08195	COG1716	ATPase activity
L2Z37_08240	COG0181	hydroxymethylbilane synthase activity
L2Z37_08250	COG3275	phosphorelay sensor kinase activity
L2Z37_08275	COG0697	spore germination
L2Z37_08300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z37_08305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z37_08310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z37_08315	COG0772	Belongs to the SEDS family
L2Z37_08340	COG4974	Belongs to the 'phage' integrase family
L2Z37_08345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z37_08355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z37_08365	COG2197	response regulator
L2Z37_08380	COG0793	Belongs to the peptidase S41A family
L2Z37_08385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z37_08390	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z37_08430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z37_08430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z37_08440	COG0004	ammonium transporteR
L2Z37_08445	COG0347	Belongs to the P(II) protein family
L2Z37_08510	COG1002	Type II restriction enzyme, methylase subunits
L2Z37_08515	COG1061	Type III restriction enzyme res subunit
L2Z37_08535	COG0659	secondary active sulfate transmembrane transporter activity
L2Z37_08540	COG0589	response to stress
L2Z37_08575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z37_08585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z37_08605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z37_08620	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z37_08630	COG0477	Major facilitator Superfamily
L2Z37_08635	COG2860	membrane
L2Z37_08645	COG1253	flavin adenine dinucleotide binding
L2Z37_08665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z37_08705	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z37_08715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z37_08785	COG0758	DNA mediated transformation
L2Z37_08795	COG0697	spore germination
L2Z37_08800	COG1309	transcriptional regulator
L2Z37_08815	COG0386	Belongs to the glutathione peroxidase family
L2Z37_08880	COG1121	(ABC) transporter
L2Z37_08885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z37_08890	COG1280	lysine exporter protein (LysE YggA)
L2Z37_08895	COG2837	iron assimilation
L2Z37_08900	COG0281	malic enzyme
L2Z37_08945	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z37_08945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z37_08950	COG4399	Belongs to the UPF0754 family
L2Z37_08955	COG2259	Doxx family
L2Z37_08960	COG0586	Pfam SNARE associated Golgi protein
L2Z37_08975	COG1192	Involved in chromosome partitioning
L2Z37_08985	COG0271	Belongs to the BolA IbaG family
L2Z37_09025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z37_09025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z37_09025	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z37_09025	COG3321	synthase
L2Z37_09030	COG1960	acyl-CoA dehydrogenase activity
L2Z37_09040	COG2197	response regulator
L2Z37_09050	COG3916	Acyl-homoserine-lactone synthase
L2Z37_09055	COG0477	Major facilitator Superfamily
L2Z37_09060	COG1024	Enoyl-CoA hydratase
L2Z37_09065	COG1024	Enoyl-CoA hydratase
L2Z37_09070	COG1960	acyl-CoA dehydrogenase activity
L2Z37_09075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z37_09095	COG1113	amino acid transport
L2Z37_09100	COG1113	amino acid transport
L2Z37_09105	COG0251	oxidation-reduction process
L2Z37_09145	COG0564	pseudouridine synthase activity
L2Z37_09190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z37_09205	COG1802	Transcriptional regulator
L2Z37_09215	COG1448	Aminotransferase
L2Z37_09220	COG0277	FAD linked oxidase domain protein
L2Z37_09230	COG2186	Transcriptional regulator
L2Z37_09240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z37_09245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z37_09260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z37_09265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z37_09290	COG2244	polysaccharide biosynthetic process
L2Z37_09295	COG1083	cytidylyl-transferase
L2Z37_09300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z37_09310	COG2089	acid synthase
L2Z37_09315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z37_09320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L2Z37_09330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z37_09335	COG1596	polysaccharide export
L2Z37_09360	COG0728	peptidoglycan biosynthetic process
L2Z37_09365	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z37_09420	COG0546	phosphoglycolate phosphatase activity
L2Z37_09425	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_09445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z37_09450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z37_09455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z37_09460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z37_09465	COG1116	anion transmembrane transporter activity
L2Z37_09470	COG1309	transcriptional regulator
L2Z37_09475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z37_09485	COG0196	riboflavin kinase activity
L2Z37_09490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z37_09500	COG1047	Peptidyl-prolyl cis-trans
L2Z37_09540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z37_09545	COG0657	acetylesterase activity
L2Z37_09565	COG0583	DNA-binding transcription factor activity
L2Z37_09595	COG2951	lytic endotransglycosylase activity
L2Z37_09600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z37_09615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z37_09625	COG0671	phosphoesterase, PA-phosphatase related
L2Z37_09630	COG0861	Integral membrane protein TerC family
L2Z37_09640	COG0754	glutathionylspermidine amidase activity
L2Z37_09650	COG0402	S-adenosylhomocysteine deaminase activity
L2Z37_09665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z37_09670	COG1230	cation diffusion facilitator family transporter
L2Z37_09685	COG0706	membrane insertase activity
L2Z37_09710	COG0592	DNA-directed DNA polymerase activity
L2Z37_09720	COG0187	DNA topoisomerase II activity
L2Z37_09730	COG0586	Pfam SNARE associated Golgi protein
L2Z37_09740	COG0488	(ABC) transporter
L2Z37_09765	COG0596	Alpha beta hydrolase
L2Z37_09770	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z37_09775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z37_09815	COG0733	neurotransmitter:sodium symporter activity
L2Z37_09850	COG0583	DNA-binding transcription factor activity
L2Z37_09855	COG2233	PERMEase
L2Z37_09870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z37_09905	COG2814	Major facilitator Superfamily
L2Z37_09910	COG0656	L-ascorbic acid biosynthetic process
L2Z37_09915	COG0583	DNA-binding transcription factor activity
L2Z37_09930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z37_09935	COG1064	alcohol dehydrogenase
L2Z37_09940	COG2818	Glycosylase
L2Z37_09955	COG1194	a g-specific adenine glycosylase
L2Z37_09975	COG2983	Belongs to the UPF0260 family
L2Z37_09980	COG2133	pyrroloquinoline quinone binding
L2Z37_09985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z37_09990	COG2116	formate transmembrane transporter activity
L2Z37_10010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z37_10015	COG1335	isochorismatase
L2Z37_10020	COG0385	Bile acid
L2Z37_10025	COG0534	Mate efflux family protein
L2Z37_10030	COG1683	Conserved Protein
L2Z37_10050	COG0625	glutathione transferase activity
L2Z37_10060	COG1113	amino acid transport
L2Z37_10070	COG0523	cobalamin synthesis protein
L2Z37_10080	COG2188	Transcriptional regulator
L2Z37_10110	COG0010	Belongs to the arginase family
L2Z37_10125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z37_10130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z37_10140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z37_10145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z37_10245	COG0534	Mate efflux family protein
L2Z37_10250	COG0436	Aminotransferase
L2Z37_10255	COG2733	membrane
L2Z37_10270	COG2918	glutathione biosynthetic process
L2Z37_10300	COG3150	esterase
L2Z37_10310	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_10315	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z37_10325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z37_10335	COG2233	PERMEase
L2Z37_10340	COG2351	hydroxyisourate hydrolase activity
L2Z37_10375	COG3706	GGDEF domain
L2Z37_10390	COG1393	Belongs to the ArsC family
L2Z37_10395	COG0708	Exodeoxyribonuclease III
L2Z37_10415	COG0189	ligase activity
L2Z37_10435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z37_10445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z37_10460	COG4942	peptidase
L2Z37_10470	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z37_10480	COG2119	membrane
L2Z37_10485	COG4774	siderophore transport
L2Z37_10490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z37_10490	COG0426	domain, Protein
L2Z37_10515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z37_10535	COG1902	pentaerythritol trinitrate reductase activity
L2Z37_10540	COG1519	Transferase
L2Z37_10545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z37_10550	COG0668	transmembrane transport
L2Z37_10560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z37_10565	COG1335	isochorismatase
L2Z37_10570	COG1522	sequence-specific DNA binding
L2Z37_10595	COG0784	Response regulator, receiver
L2Z37_10595	COG2198	Histidine kinase
L2Z37_10595	COG2205	protein histidine kinase activity
L2Z37_10600	COG3162	membrane
L2Z37_10605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z37_10615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z37_10635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z37_10640	COG1309	transcriptional regulator
L2Z37_10660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z37_10660	COG0352	thiamine-phosphate diphosphorylase activity
L2Z37_10660	COG0351	phosphomethylpyrimidine kinase
L2Z37_10670	COG2814	Major facilitator Superfamily
L2Z37_10685	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z37_10695	COG1113	amino acid transport
L2Z37_10705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z37_10710	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_10720	COG1335	isochorismatase
L2Z37_10750	COG2814	Major facilitator Superfamily
L2Z37_10755	COG0583	DNA-binding transcription factor activity
L2Z37_10775	COG0667	Aldo Keto reductase
L2Z37_10810	COG1733	regulation of RNA biosynthetic process
L2Z37_10815	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z37_10880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z37_10895	COG2329	Antibiotic biosynthesis monooxygenase
L2Z37_10925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z37_10955	COG0427	acetyl-CoA hydrolase
L2Z37_10980	COG0659	secondary active sulfate transmembrane transporter activity
L2Z37_10985	COG4221	oxidoreductase activity
L2Z37_10990	COG2873	o-acetylhomoserine
L2Z37_10995	COG0488	(ABC) transporter
L2Z37_11080	COG0833	amino acid
L2Z37_11125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z37_11130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z37_11145	COG2226	methyltransferase
L2Z37_11195	COG0067	glutamate synthase
L2Z37_11195	COG0069	glutamate synthase activity
L2Z37_11195	COG0070	glutamate synthase
L2Z37_11200	COG0493	'glutamate synthase
L2Z37_11210	COG1704	LemA family
L2Z37_11215	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z37_11235	COG3307	-O-antigen
L2Z37_11255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z37_11270	COG0194	GDP metabolic process
L2Z37_11320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z37_11340	COG5380	lipid catabolic process
L2Z37_11345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z37_11370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z37_11375	COG0277	FAD linked oxidase domain protein
L2Z37_11385	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z37_11390	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z37_11405	COG1289	transmembrane transporter activity
L2Z37_11415	COG0628	permease
L2Z37_11420	COG1192	Involved in chromosome partitioning
L2Z37_11450	COG0833	amino acid
L2Z37_11455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z37_11460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z37_11470	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_11510	COG0583	DNA-binding transcription factor activity
L2Z37_11555	COG0517	IMP dehydrogenase activity
L2Z37_11560	COG1983	PspC domain protein
L2Z37_11570	COG1960	acyl-CoA dehydrogenase activity
L2Z37_11585	COG0408	coproporphyrinogen oxidase activity
L2Z37_11605	COG0513	Belongs to the DEAD box helicase family
L2Z37_11615	COG1127	ABC transporter
L2Z37_11620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z37_11630	COG2854	intermembrane phospholipid transfer
L2Z37_11640	COG0598	Magnesium transport protein CorA
L2Z37_11650	COG0494	nUDIX hydrolase
L2Z37_11655	COG1040	competence protein
L2Z37_11660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z37_11680	COG1946	Acyl-CoA thioesterase
L2Z37_11685	COG1301	dicarboxylic acid transport
L2Z37_11700	COG1959	2 iron, 2 sulfur cluster binding
L2Z37_11705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z37_11705	COG1017	nitric oxide dioxygenase activity
L2Z37_11710	COG0433	COG0433 Predicted ATPase
L2Z37_11715	COG0626	cystathionine gamma-synthase activity
L2Z37_11870	COG1960	acyl-CoA dehydrogenase activity
L2Z37_11875	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z37_11905	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z37_11910	COG0339	signal peptide processing
L2Z37_11915	COG0557	exoribonuclease II activity
L2Z37_11960	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z37_11965	COG2169	Transcriptional regulator
L2Z37_11970	COG0697	spore germination
L2Z37_11975	COG1295	ribonuclease BN
L2Z37_12010	COG1702	phosphate starvation-inducible protein PhoH
L2Z37_12020	COG0741	lytic transglycosylase activity
L2Z37_12020	COG1196	nuclear chromosome segregation
L2Z37_12020	COG0739	heme binding
L2Z37_12050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z37_12055	COG1183	phosphatidylcholine synthase activity
L2Z37_12100	COG1960	acyl-CoA dehydrogenase activity
L2Z37_12105	COG1309	transcriptional regulator
L2Z37_12120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z37_12125	COG1960	acyl-CoA dehydrogenase activity
L2Z37_12145	COG2969	positive regulation of protein catabolic process
L2Z37_12155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z37_12170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z37_12175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z37_12195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z37_12205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z37_12210	COG1408	metallophosphoesterase
L2Z37_12220	COG2199	diguanylate cyclase activity
L2Z37_12280	COG1607	acyl-coa hydrolase
L2Z37_12310	COG2350	Protein conserved in bacteria
L2Z37_12320	COG0613	PHP domain protein
L2Z37_12325	COG3781	membrane
L2Z37_12335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z37_12340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z37_12350	COG1862	Preprotein translocase
L2Z37_12380	COG2205	protein histidine kinase activity
L2Z37_12385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z37_12405	COG0726	polysaccharide deacetylase
L2Z37_12410	COG0463	Glycosyl transferase, family 2
L2Z37_12415	COG0438	transferase activity, transferring glycosyl groups
L2Z37_12480	COG0625	glutathione transferase activity
L2Z37_12485	COG0583	DNA-binding transcription factor activity
L2Z37_12490	COG1960	acyl-CoA dehydrogenase activity
L2Z37_12495	COG1960	acyl-CoA dehydrogenase activity
L2Z37_12505	COG2205	protein histidine kinase activity
L2Z37_12510	COG0745	RESPONSE REGULATOR receiver
L2Z37_12515	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z37_12535	COG2096	Adenosyltransferase
L2Z37_12585	COG0285	dihydrofolate synthase activity
L2Z37_12605	COG0450	alkyl hydroperoxide reductase
L2Z37_12620	COG0477	Major facilitator Superfamily
L2Z37_12625	COG1272	protein, Hemolysin III
L2Z37_12655	COG0183	Belongs to the thiolase family
L2Z37_12660	COG2207	Transcriptional regulator
L2Z37_12680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z37_12700	COG0183	Belongs to the thiolase family
L2Z37_12710	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z37_12710	COG2885	chlorophyll binding
L2Z37_12720	COG1690	Belongs to the RtcB family
L2Z37_12725	COG0833	amino acid
L2Z37_12735	COG2233	PERMEase
L2Z37_12740	COG1217	gtp-binding protein TYPA
L2Z37_12785	COG1902	pentaerythritol trinitrate reductase activity
L2Z37_12800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z37_12805	COG0354	folic acid binding
L2Z37_12815	COG3189	MarR family transcriptional regulator
L2Z37_12820	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z37_12825	COG3422	double-strand break repair
L2Z37_12865	COG0840	transmembrane signaling receptor activity
L2Z37_12885	COG5510	response to toxic substance
L2Z37_12895	COG2832	Protein of unknown function (DUF454)
L2Z37_12900	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z37_12940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z37_12950	COG1289	transmembrane transporter activity
L2Z37_12955	COG2814	Major facilitator Superfamily
L2Z37_12975	COG1115	amino acid carrier protein
L2Z37_12980	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z37_12985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z37_12990	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z37_13020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z37_13030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z37_13035	COG1077	Cell shape determining protein MreB Mrl
L2Z37_13040	COG1792	Involved in formation and maintenance of cell shape
L2Z37_13045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z37_13050	COG0424	maF-like protein
L2Z37_13055	COG1530	ribonuclease E activity
L2Z37_13065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z37_13075	COG0560	Phosphoserine phosphatase
L2Z37_13085	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z37_13110	COG2207	Transcriptional regulator
L2Z37_13130	COG1113	amino acid transport
L2Z37_13135	COG2828	Protein conserved in bacteria
L2Z37_13140	COG0142	geranyltranstransferase activity
L2Z37_13145	COG2315	Protein conserved in bacteria
L2Z37_13160	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z37_13180	COG2194	sulfuric ester hydrolase activity
L2Z37_13185	COG0745	RESPONSE REGULATOR receiver
L2Z37_13190	COG0642	Histidine kinase
L2Z37_13200	COG0004	ammonium transporteR
L2Z37_13205	COG0583	DNA-binding transcription factor activity
L2Z37_13225	COG0525	valine-tRNA ligase activity
L2Z37_13235	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_13245	COG0393	Putative heavy-metal-binding
L2Z37_13250	COG0393	Putative heavy-metal-binding
L2Z37_13255	COG1538	Outer membrane efflux protein
L2Z37_13265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z37_13270	COG0671	phosphoesterase, PA-phosphatase related
L2Z37_13300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z37_13315	COG1648	precorrin-2 dehydrogenase activity
L2Z37_13315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z37_13320	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z37_13325	COG1733	regulation of RNA biosynthetic process
L2Z37_13335	COG0531	amino acid
L2Z37_13350	COG0321	lipoyl(octanoyl) transferase activity
L2Z37_13355	COG2921	Belongs to the UPF0250 family
L2Z37_13395	COG2009	succinate dehydrogenase
L2Z37_13400	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z37_13405	COG1053	succinate dehydrogenase
L2Z37_13410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z37_13435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z37_13455	COG2354	Protein conserved in bacteria
L2Z37_13460	COG2321	neutral zinc metallopeptidase
L2Z37_13480	COG2843	Capsule synthesis protein
L2Z37_13495	COG0589	response to stress
L2Z37_13515	COG0505	Belongs to the CarA family
L2Z37_13540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z37_13545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z37_13595	COG0477	Major facilitator Superfamily
L2Z37_13600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z37_13615	COG1597	lipid kinase activity
L2Z37_13620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z37_13650	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z37_13670	COG0741	lytic transglycosylase activity
L2Z37_13690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z37_13705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z37_13735	COG0778	Nitroreductase
L2Z37_13750	COG1929	Belongs to the glycerate kinase type-1 family
L2Z37_13755	COG0243	molybdopterin cofactor binding
L2Z37_13760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z37_13765	COG3339	Conserved Protein
L2Z37_13775	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z37_13790	COG1113	amino acid transport
L2Z37_13800	COG0019	diaminopimelate decarboxylase activity
L2Z37_13810	COG1280	lysine exporter protein (LysE YggA)
L2Z37_13815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z37_13845	COG0463	Glycosyl transferase, family 2
L2Z37_13865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z37_13900	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z37_13905	COG1136	(ABC) transporter
L2Z37_13910	COG2333	competence protein COMEC
L2Z37_13910	COG0658	competence protein
L2Z37_13920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z37_13920	COG0616	signal peptide processing
L2Z37_13925	COG0596	Alpha beta hydrolase
L2Z37_13930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z37_13940	COG0628	permease
L2Z37_13975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z37_13995	COG0823	Involved in the tonB-independent uptake of proteins
L2Z37_14015	COG0824	Thioesterase
L2Z37_14020	COG1473	amidohydrolase
L2Z37_14040	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z37_14040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z37_14045	COG2814	Major facilitator Superfamily
L2Z37_14055	COG1024	Enoyl-CoA hydratase
L2Z37_14060	COG1051	belongs to the nudix hydrolase family
L2Z37_14060	COG1056	cytidyltransferase-related domain
L2Z37_14070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z37_14085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z37_14100	COG4625	pathogenesis
L2Z37_14105	COG0583	DNA-binding transcription factor activity
L2Z37_14110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z37_14115	COG4208	sulfate ABC transporter
L2Z37_14120	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z37_14130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z37_14135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z37_14140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z37_14160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z37_14175	COG0681	Belongs to the peptidase S26 family
L2Z37_14190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z37_14200	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z37_14205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z37_14215	COG4221	oxidoreductase activity
L2Z37_14245	COG0436	Aminotransferase
L2Z37_14265	COG0556	nucleotide-excision repair
L2Z37_14465	COG5410	chromosome segregation
L2Z37_14655	COG2070	2-Nitropropane dioxygenase
L2Z37_14685	COG1215	transferase activity, transferring glycosyl groups
L2Z37_14700	COG0415	Belongs to the DNA photolyase family
L2Z37_14710	COG1252	NADH dehydrogenase
L2Z37_14715	COG1686	Belongs to the peptidase S11 family
L2Z37_14730	COG1187	pseudouridine synthase activity
L2Z37_14755	COG0477	Major facilitator Superfamily
L2Z37_14760	COG0583	DNA-binding transcription factor activity
L2Z37_14765	COG1823	symporter activity
L2Z37_14775	COG0612	Peptidase, M16
L2Z37_14800	COG0352	thiamine-phosphate diphosphorylase activity
L2Z37_14835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z37_14850	COG1309	transcriptional regulator
L2Z37_14860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z37_14865	COG0076	glutamate decarboxylase activity
L2Z37_14875	COG1522	sequence-specific DNA binding
L2Z37_14880	COG3961	Belongs to the TPP enzyme family
L2Z37_14885	COG1113	amino acid transport
L2Z37_14890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z37_14895	COG0573	inorganic phosphate transmembrane transporter activity
L2Z37_14905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z37_14910	COG0616	signal peptide processing
L2Z37_14945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z37_14950	COG1686	Belongs to the peptidase S11 family
L2Z37_14975	COG0583	DNA-binding transcription factor activity
L2Z37_14980	COG1067	ATP-dependent peptidase activity
L2Z37_15025	COG1966	Carbon starvation protein
L2Z37_15030	COG2879	small protein
L2Z37_15065	COG2508	Transcriptional regulator
L2Z37_15065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z37_15085	COG1113	amino acid transport
L2Z37_15090	COG0583	DNA-binding transcription factor activity
L2Z37_15095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z37_15100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z37_15110	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_15120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z37_15125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z37_15125	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z37_15160	COG2814	Major facilitator Superfamily
L2Z37_15165	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z37_15175	COG1309	transcriptional regulator
L2Z37_15195	COG1741	Belongs to the pirin family
L2Z37_15205	COG2964	Protein conserved in bacteria
L2Z37_15220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z37_15225	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z37_15230	COG4605	iron ion homeostasis
L2Z37_15235	COG4604	ABC transporter, ATP-binding protein
L2Z37_15240	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z37_15245	COG4774	siderophore transport
L2Z37_15255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z37_15260	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z37_15265	COG1535	isochorismatase
L2Z37_15265	COG3433	isochorismatase activity
L2Z37_15275	COG1132	(ABC) transporter
L2Z37_15280	COG1132	(ABC) transporter
L2Z37_15285	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z37_15295	COG1169	isochorismate synthase
L2Z37_15310	COG3739	integral membrane protein
L2Z37_15340	COG0302	gtp cyclohydrolase
L2Z37_15350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z37_15380	COG0308	aminopeptidase N
L2Z37_15385	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z37_15400	COG0174	glutamine synthetase
L2Z37_15410	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z37_15445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z37_15450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z37_15455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z37_15475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z37_15480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z37_15485	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z37_15500	COG1960	acyl-CoA dehydrogenase activity
L2Z37_15505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z37_15510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z37_15520	COG2223	nitrite transmembrane transporter activity
L2Z37_15530	COG0024	Methionine aminopeptidase
L2Z37_15535	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z37_15550	COG2207	Transcriptional regulator
L2Z37_15575	COG2951	lytic endotransglycosylase activity
L2Z37_15580	COG0772	Belongs to the SEDS family
L2Z37_15595	COG0842	Transport permease protein
L2Z37_15600	COG1131	(ABC) transporter
L2Z37_15645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z37_15660	COG4215	(ABC) transporter
L2Z37_15665	COG4160	amino acid transport
L2Z37_15670	COG4598	ABC transporter
L2Z37_15680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z37_15685	COG0826	peptidase U32
L2Z37_15690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z37_15705	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z37_15715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z37_15730	COG0642	Histidine kinase
L2Z37_15740	COG0494	nUDIX hydrolase
L2Z37_15750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z37_15755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z37_15760	COG3139	Protein of unknown function (DUF1315)
L2Z37_15765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z37_15770	COG1301	dicarboxylic acid transport
L2Z37_15775	COG1960	acyl-CoA dehydrogenase activity
L2Z37_15780	COG2819	hydrolase of the alpha beta superfamily
L2Z37_15790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z37_15800	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z37_15805	COG1234	tRNA 3'-trailer cleavage
L2Z37_15835	COG2363	Small membrane protein
L2Z37_15860	COG0513	Belongs to the DEAD box helicase family
L2Z37_15870	COG0778	Nitroreductase
L2Z37_15900	COG1286	toxin biosynthetic process
L2Z37_15925	COG4783	chaperone-mediated protein folding
L2Z37_15930	COG1610	YqeY-like protein
L2Z37_16030	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z37_16055	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z37_16060	COG0786	glutamate:sodium symporter activity
L2Z37_16070	COG2186	Transcriptional regulator
L2Z37_16120	COG0477	Major facilitator Superfamily
L2Z37_16150	COG2985	domain, Protein
L2Z37_16160	COG2995	paraquat-inducible protein a
L2Z37_16165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z37_16165	COG3008	intermembrane lipid transfer
L2Z37_16175	COG1794	racemase activity, acting on amino acids and derivatives
L2Z37_16280	COG0590	tRNA wobble adenosine to inosine editing
L2Z37_16285	COG2807	transmembrane transport
L2Z37_16300	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z37_16315	COG0789	Transcriptional regulator
L2Z37_16325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z37_16345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z37_16355	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z37_16370	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_16375	COG0531	amino acid
L2Z37_16380	COG1760	l-serine dehydratase
L2Z37_16385	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_16385	COG2030	dehydratase
L2Z37_16390	COG3396	Phenylacetate-CoA oxygenase
L2Z37_16395	COG3460	Phenylacetate-CoA oxygenase
L2Z37_16400	COG3396	Phenylacetate-CoA oxygenase
L2Z37_16405	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z37_16410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z37_16515	COG0488	(ABC) transporter
L2Z37_16520	COG3173	Aminoglycoside phosphotransferase
L2Z37_16530	COG2433	Pfam Transposase IS66
L2Z37_16590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z37_16595	COG2011	ABC-type metal ion transport system permease component
L2Z37_16600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z37_16605	COG1464	Belongs to the NlpA lipoprotein family
L2Z37_16610	COG0151	Belongs to the GarS family
L2Z37_16615	COG0138	bifunctional purine biosynthesis protein purh
L2Z37_16620	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z37_16650	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z37_16660	COG1305	Transglutaminase-like
L2Z37_16670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z37_16675	COG0305	Participates in initiation and elongation during chromosome replication
L2Z37_16700	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z37_16710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z37_16715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z37_16740	COG0726	polysaccharide deacetylase
L2Z37_16740	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z37_16745	COG1215	transferase activity, transferring glycosyl groups
L2Z37_16750	COG3658	cytochrome
L2Z37_16760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z37_16775	COG0583	DNA-binding transcription factor activity
L2Z37_16795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z37_16800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z37_16815	COG1960	acyl-CoA dehydrogenase activity
L2Z37_16820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z37_16825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z37_16850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z37_16855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z37_16865	COG2205	protein histidine kinase activity
L2Z37_16870	COG0745	RESPONSE REGULATOR receiver
L2Z37_16875	COG0174	glutamine synthetase
L2Z37_16895	COG0729	surface antigen
L2Z37_16920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z37_16925	COG2814	Major facilitator Superfamily
L2Z37_16940	COG0583	DNA-binding transcription factor activity
L2Z37_16955	COG1187	pseudouridine synthase activity
L2Z37_16975	COG0802	atpase or kinase
L2Z37_16980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z37_16990	COG1923	regulation of RNA biosynthetic process
L2Z37_16995	COG0697	spore germination
L2Z37_17010	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z37_17020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z37_17025	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z37_17025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z37_17030	COG4302	ethanolamine ammonia-lyase activity
L2Z37_17035	COG4303	Ethanolamine ammonia lyase large subunit
L2Z37_17040	COG0531	amino acid
L2Z37_17060	COG1454	alcohol dehydrogenase
L2Z37_17065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z37_17075	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z37_17095	COG0308	aminopeptidase N
L2Z37_17105	COG4221	oxidoreductase activity
L2Z37_17115	COG1605	Chorismate mutase
L2Z37_17135	COG1309	transcriptional regulator
L2Z37_17145	COG0668	transmembrane transport
L2Z37_17180	COG4773	Receptor
L2Z37_17200	COG0488	(ABC) transporter
L2Z37_17205	COG0589	response to stress
L2Z37_17230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z37_17240	COG3135	benzoate transporter
L2Z37_17245	COG1522	sequence-specific DNA binding
L2Z37_17255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z37_17260	COG0583	DNA-binding transcription factor activity
L2Z37_17270	COG0183	Belongs to the thiolase family
L2Z37_17280	COG2030	dehydratase
L2Z37_17285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z37_17300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z37_17310	COG0824	Thioesterase
L2Z37_17315	COG1454	alcohol dehydrogenase
L2Z37_17325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z37_17345	COG0069	glutamate synthase activity
L2Z37_17365	COG2814	Major facilitator Superfamily
L2Z37_17380	COG0511	ligase activity, forming carbon-carbon bonds
L2Z37_17400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z37_17400	COG1116	anion transmembrane transporter activity
L2Z37_17405	COG0745	RESPONSE REGULATOR receiver
L2Z37_17415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z37_17415	COG2146	nitrite reductase [NAD(P)H] activity
L2Z37_17420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z37_17425	COG0243	molybdopterin cofactor binding
L2Z37_17435	COG0243	molybdopterin cofactor binding
L2Z37_17440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z37_17455	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z37_17455	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z37_17460	COG0303	'Molybdopterin
L2Z37_17470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z37_17475	COG0697	spore germination
L2Z37_17495	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z37_17500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z37_17555	COG2204	response regulator
L2Z37_17560	COG3852	Histidine kinase
L2Z37_17580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z37_17585	COG0575	Belongs to the CDS family
L2Z37_17620	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z37_17635	COG2137	regulation of response to DNA damage stimulus
L2Z37_17645	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z37_17650	COG1011	Hydrolase
L2Z37_17675	COG1522	sequence-specific DNA binding
L2Z37_17685	COG1113	amino acid transport
L2Z37_17705	COG0659	secondary active sulfate transmembrane transporter activity
L2Z37_17710	COG2135	peptidase activity
L2Z37_17745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z37_17745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z37_17745	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z37_17750	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z37_17755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z37_17755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z37_17785	COG0024	Methionine aminopeptidase
L2Z37_17790	COG0583	DNA-binding transcription factor activity
L2Z37_17800	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z37_17805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z37_17810	COG0516	GMP reductase activity
L2Z37_17810	COG0517	IMP dehydrogenase activity
L2Z37_17835	COG0552	protein localization to endoplasmic reticulum
L2Z37_17845	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z37_17860	COG4890	Cyd operon protein YbgT
L2Z37_17865	COG1294	oxidase, subunit
L2Z37_17885	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z37_17895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z37_17900	COG4774	siderophore transport
L2Z37_17915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z37_17920	COG0569	domain protein
L2Z37_17925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z37_17955	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z37_17960	COG0542	response to heat
L2Z37_17985	COG1902	pentaerythritol trinitrate reductase activity
L2Z37_17985	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z37_18030	COG2323	membrane
L2Z37_18035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z37_18045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z37_18050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z37_18055	COG0183	Belongs to the thiolase family
L2Z37_18060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z37_18065	COG0596	Alpha beta hydrolase
L2Z37_18070	COG2271	Major facilitator Superfamily
L2Z37_18075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z37_18080	COG3485	protocatechuate 3,4-dioxygenase
L2Z37_18085	COG3485	protocatechuate 3,4-dioxygenase
L2Z37_18090	COG0710	3-dehydroquinate dehydratase activity
L2Z37_18095	COG3420	alginic acid biosynthetic process
L2Z37_18100	COG3659	wide pore channel activity
L2Z37_18105	COG4993	Dehydrogenase
L2Z37_18115	COG2391	methyltransferase activity
L2Z37_18130	COG1414	Transcriptional regulator
L2Z37_18135	COG0583	DNA-binding transcription factor activity
L2Z37_18140	COG1960	acyl-CoA dehydrogenase activity
L2Z37_18165	COG2814	Major facilitator Superfamily
L2Z37_18175	COG0154	amidase activity
L2Z37_18195	COG4638	Rieske (2fe-2S)
L2Z37_18205	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_18215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z37_18225	COG3733	amine oxidase
L2Z37_18235	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_18245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z37_18250	COG0183	Belongs to the thiolase family
L2Z37_18255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z37_18260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z37_18270	COG4829	muconolactone delta-isomerase
L2Z37_18275	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z37_18280	COG0583	DNA-binding transcription factor activity
L2Z37_18290	COG2186	Transcriptional regulator
L2Z37_18310	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_18330	COG1960	acyl-CoA dehydrogenase activity
L2Z37_18335	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_18340	COG3829	transcription factor binding
L2Z37_18350	COG3162	membrane
L2Z37_18365	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_18380	COG0753	catalase activity
L2Z37_18400	COG1846	Transcriptional regulator
L2Z37_18405	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z37_18405	COG1902	pentaerythritol trinitrate reductase activity
L2Z37_18415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z37_18445	COG1309	transcriptional regulator
L2Z37_18455	COG1335	isochorismatase
L2Z37_18460	COG0583	DNA-binding transcription factor activity
L2Z37_18470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z37_18470	COG0475	glutathione-regulated potassium exporter activity
L2Z37_18480	COG1473	amidohydrolase
L2Z37_18490	COG2831	hemolysin activation secretion protein
L2Z37_18495	COG3210	domain, Protein
L2Z37_18525	COG2188	Transcriptional regulator
L2Z37_18540	COG0583	DNA-binding transcription factor activity
L2Z37_18570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z37_18600	COG1566	PFAM secretion protein HlyD family protein
L2Z37_18615	COG1012	belongs to the aldehyde dehydrogenase family
L2Z37_18620	COG0129	dihydroxy-acid dehydratase activity
L2Z37_18630	COG0583	DNA-binding transcription factor activity
L2Z37_18635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z37_18645	COG2084	Dehydrogenase
L2Z37_18650	COG2207	Transcriptional regulator
L2Z37_18665	COG1064	alcohol dehydrogenase
L2Z37_18675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z37_18680	COG1120	ATPase activity
L2Z37_18700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z37_18820	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z37_18870	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_18885	COG2207	Transcriptional regulator
L2Z37_18895	COG2205	protein histidine kinase activity
L2Z37_18900	COG0745	RESPONSE REGULATOR receiver
L2Z37_18905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z37_18910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z37_18915	COG1538	Outer membrane efflux protein
L2Z37_18925	COG2072	flavoprotein involved in K transport
L2Z37_18945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z37_18965	COG3539	Fimbrial protein
L2Z37_18975	COG2963	transposase activity
L2Z37_18985	COG4372	Transposase
L2Z37_19015	COG3433	isochorismatase activity
L2Z37_19015	COG1535	isochorismatase
L2Z37_19020	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_19025	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z37_19030	COG4149	molybdate abc transporter
L2Z37_19035	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z37_19045	COG4638	Rieske (2fe-2S)
L2Z37_19050	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z37_19055	COG0543	2 iron, 2 sulfur cluster binding
L2Z37_19055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z37_19080	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_19095	COG2207	Transcriptional regulator
L2Z37_19105	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z37_19110	COG2610	gluconate transmembrane transporter activity
L2Z37_19120	COG0583	DNA-binding transcription factor activity
L2Z37_19130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z37_19135	COG2031	fatty acid transporter
L2Z37_19140	COG0183	Belongs to the thiolase family
L2Z37_19145	COG0583	DNA-binding transcription factor activity
L2Z37_19150	COG0583	DNA-binding transcription factor activity
L2Z37_19165	COG1027	Aspartate ammonia-lyase
L2Z37_19175	COG0477	Major facilitator Superfamily
L2Z37_19195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z37_19200	COG4521	taurine ABC transporter
L2Z37_19215	COG2188	Transcriptional regulator
L2Z37_19225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z37_19230	COG1733	regulation of RNA biosynthetic process
L2Z37_19235	COG2207	Transcriptional regulator
L2Z37_19235	COG3708	Transcriptional regulator
L2Z37_19250	COG0730	response to heat
L2Z37_19265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z37_19265	COG3453	Protein conserved in bacteria