locus-tag	class	description
L2Z07_00135	COG0305	Participates in initiation and elongation during chromosome replication
L2Z07_00230	COG4695	Portal protein
L2Z07_00370	COG0006	proline dipeptidase activity
L2Z07_00375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z07_00380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z07_00400	COG1279	arginine transmembrane transporter activity
L2Z07_00405	COG0583	DNA-binding transcription factor activity
L2Z07_00445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z07_00450	COG1388	LysM domain
L2Z07_00450	COG0741	lytic transglycosylase activity
L2Z07_00450	COG0741	lytic transglycosylase activity
L2Z07_00450	COG1388	LysM domain
L2Z07_00460	COG4174	ABC transporter (Permease)
L2Z07_00465	COG4239	(ABC) transporter, permease
L2Z07_00470	COG4172	Belongs to the ABC transporter superfamily
L2Z07_00520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z07_00530	COG5001	Diguanylate cyclase
L2Z07_00530	COG4251	negative regulation of phosphorylation
L2Z07_00530	COG2203	Gaf domain
L2Z07_00530	COG3706	GGDEF domain
L2Z07_00540	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z07_00540	COG1902	pentaerythritol trinitrate reductase activity
L2Z07_00575	COG3209	COG3209 Rhs family protein
L2Z07_00605	COG1113	amino acid transport
L2Z07_00615	COG0531	amino acid
L2Z07_00635	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_00655	COG1113	amino acid transport
L2Z07_00695	COG0697	spore germination
L2Z07_00700	COG2721	sulfolactate sulfo-lyase activity
L2Z07_00705	COG2271	Major facilitator Superfamily
L2Z07_00710	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z07_00720	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_00725	COG2186	Transcriptional regulator
L2Z07_00750	COG1960	acyl-CoA dehydrogenase activity
L2Z07_00760	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_00765	COG1024	Enoyl-CoA hydratase
L2Z07_00770	COG2814	Major facilitator Superfamily
L2Z07_00785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z07_00830	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L2Z07_00835	COG2072	flavoprotein involved in K transport
L2Z07_00840	COG0300	oxidoreductase activity
L2Z07_00850	COG1309	transcriptional regulator
L2Z07_00855	COG1741	Belongs to the pirin family
L2Z07_00870	COG2072	flavoprotein involved in K transport
L2Z07_00880	COG2252	PERMEase
L2Z07_00885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z07_00890	COG3038	cytochrome b561
L2Z07_00900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z07_00910	COG0527	aspartate kinase activity
L2Z07_00950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z07_01030	COG1484	DNA-dependent DNA replication
L2Z07_01240	COG0592	DNA-directed DNA polymerase activity
L2Z07_01315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z07_01345	COG0582	viral genome integration into host DNA
L2Z07_01355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z07_01365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z07_01380	COG0667	Aldo Keto reductase
L2Z07_01395	COG1765	OsmC-like protein
L2Z07_01410	COG0542	response to heat
L2Z07_01445	COG2885	chlorophyll binding
L2Z07_01455	COG0625	glutathione transferase activity
L2Z07_01460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z07_01480	COG3634	alkyl hydroperoxide reductase activity
L2Z07_01490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z07_01500	COG0450	alkyl hydroperoxide reductase
L2Z07_01505	COG1643	Atp-dependent helicase
L2Z07_01520	COG2814	Major facilitator Superfamily
L2Z07_01525	COG3135	benzoate transporter
L2Z07_01530	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_01535	COG0543	2 iron, 2 sulfur cluster binding
L2Z07_01535	COG0633	Ferredoxin
L2Z07_01545	COG4638	Rieske (2fe-2S)
L2Z07_01555	COG0583	DNA-binding transcription factor activity
L2Z07_01605	COG1570	exodeoxyribonuclease VII activity
L2Z07_01640	COG1278	Cold shock
L2Z07_01675	COG2814	Major facilitator Superfamily
L2Z07_01745	COG5410	chromosome segregation
L2Z07_01750	COG3567	Phage-associated protein, HI1409 family
L2Z07_01770	COG3566	protein conserved in bacteria
L2Z07_01785	COG5434	Belongs to the glycosyl hydrolase 28 family
L2Z07_01850	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z07_01860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z07_01865	COG1137	ATPase activity
L2Z07_01870	COG1538	Outer membrane efflux protein
L2Z07_01900	COG4122	O-methyltransferase activity
L2Z07_01910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z07_01925	COG1522	sequence-specific DNA binding
L2Z07_01930	COG5006	permease, DMT superfamily
L2Z07_01940	COG1560	Kdo2-lipid A biosynthetic process
L2Z07_01955	COG2814	Major facilitator Superfamily
L2Z07_02020	COG3209	COG3209 Rhs family protein
L2Z07_02040	COG0583	DNA-binding transcription factor activity
L2Z07_02045	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z07_02065	COG4770	biotin carboxylase activity
L2Z07_02070	COG0038	chloride channel
L2Z07_02095	COG1309	transcriptional regulator
L2Z07_02105	COG1063	alcohol dehydrogenase
L2Z07_02120	COG0439	Biotin carboxylase
L2Z07_02125	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z07_02130	COG1733	regulation of RNA biosynthetic process
L2Z07_02140	COG0864	Transcriptional regulator
L2Z07_02150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z07_02155	COG1116	anion transmembrane transporter activity
L2Z07_02275	COG0590	tRNA wobble adenosine to inosine editing
L2Z07_02280	COG2807	transmembrane transport
L2Z07_02295	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z07_02305	COG0789	Transcriptional regulator
L2Z07_02315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z07_02335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z07_02360	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_02365	COG0531	amino acid
L2Z07_02370	COG1760	l-serine dehydratase
L2Z07_02375	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_02375	COG2030	dehydratase
L2Z07_02380	COG3396	Phenylacetate-CoA oxygenase
L2Z07_02385	COG3460	Phenylacetate-CoA oxygenase
L2Z07_02390	COG3396	Phenylacetate-CoA oxygenase
L2Z07_02395	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z07_02400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z07_02405	COG1024	Enoyl-CoA hydratase
L2Z07_02410	COG1024	Enoyl-CoA hydratase
L2Z07_02415	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z07_02420	COG0183	Belongs to the thiolase family
L2Z07_02425	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z07_02430	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z07_02440	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z07_02450	COG0210	DNA helicase
L2Z07_02485	COG1278	Cold shock
L2Z07_02515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z07_02520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z07_02525	COG2271	Major facilitator Superfamily
L2Z07_02530	COG0753	catalase activity
L2Z07_02535	COG3038	cytochrome b561
L2Z07_02555	COG2267	carboxylic ester hydrolase activity
L2Z07_02560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z07_02565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z07_02570	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_02580	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z07_02590	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_02595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z07_02600	COG0583	DNA-binding transcription factor activity
L2Z07_02610	COG1414	Transcriptional regulator
L2Z07_02615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z07_02625	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z07_02630	COG3842	ATPase activity
L2Z07_02645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z07_02650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z07_02655	COG2814	Major facilitator Superfamily
L2Z07_02660	COG1960	acyl-CoA dehydrogenase activity
L2Z07_02665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z07_02675	COG1024	Enoyl-CoA hydratase
L2Z07_02685	COG2814	Major facilitator Superfamily
L2Z07_02695	COG0183	Belongs to the thiolase family
L2Z07_02700	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z07_02705	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_02710	COG1024	Enoyl-CoA hydratase
L2Z07_02715	COG1960	acyl-CoA dehydrogenase activity
L2Z07_02720	COG2814	Major facilitator Superfamily
L2Z07_02725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z07_02730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z07_02740	COG2814	Major facilitator Superfamily
L2Z07_02750	COG1960	acyl-CoA dehydrogenase activity
L2Z07_02765	COG0583	DNA-binding transcription factor activity
L2Z07_02775	COG4770	biotin carboxylase activity
L2Z07_02780	COG1024	Enoyl-CoA hydratase
L2Z07_02785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z07_02790	COG1960	acyl-CoA dehydrogenase activity
L2Z07_02795	COG1309	transcriptional regulator
L2Z07_02800	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z07_02820	COG0583	DNA-binding transcription factor activity
L2Z07_02870	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_02915	COG0784	Response regulator, receiver
L2Z07_02915	COG2205	protein histidine kinase activity
L2Z07_02935	COG0765	amino acid transport
L2Z07_02940	COG0765	amino acid transport
L2Z07_02945	COG1126	abc transporter atp-binding protein
L2Z07_02950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z07_02955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z07_02970	COG1280	lysine exporter protein (LysE YggA)
L2Z07_02980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z07_02985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z07_02995	COG1045	serine acetyltransferase
L2Z07_03010	COG0583	DNA-binding transcription factor activity
L2Z07_03015	COG0625	glutathione transferase activity
L2Z07_03020	COG0625	glutathione transferase activity
L2Z07_03025	COG0583	DNA-binding transcription factor activity
L2Z07_03035	COG1346	cytolysis
L2Z07_03040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z07_03055	COG2814	Major facilitator Superfamily
L2Z07_03065	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z07_03070	COG3052	prosthetic group binding
L2Z07_03090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z07_03110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z07_03120	COG1294	oxidase, subunit
L2Z07_03125	COG1271	oxidase subunit
L2Z07_03145	COG0477	Major facilitator Superfamily
L2Z07_03155	COG4521	taurine ABC transporter
L2Z07_03160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z07_03165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z07_03170	COG2175	clavaminate synthase activity
L2Z07_03180	COG1953	Uracil, thiamine, allantoin
L2Z07_03190	COG0583	DNA-binding transcription factor activity
L2Z07_03200	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z07_03215	COG0640	Transcriptional regulator
L2Z07_03220	COG0798	PFAM Bile acid sodium symporter
L2Z07_03225	COG0583	DNA-binding transcription factor activity
L2Z07_03240	COG3634	alkyl hydroperoxide reductase activity
L2Z07_03275	COG1301	dicarboxylic acid transport
L2Z07_03280	COG0436	Aminotransferase
L2Z07_03290	COG0386	Belongs to the glutathione peroxidase family
L2Z07_03330	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z07_03355	COG0012	GTP binding
L2Z07_03360	COG2011	ABC-type metal ion transport system permease component
L2Z07_03365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z07_03375	COG1464	Belongs to the NlpA lipoprotein family
L2Z07_03405	COG0765	amino acid transport
L2Z07_03410	COG0765	amino acid transport
L2Z07_03415	COG1126	abc transporter atp-binding protein
L2Z07_03425	COG1522	sequence-specific DNA binding
L2Z07_03470	COG0583	DNA-binding transcription factor activity
L2Z07_03480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z07_03490	COG0697	spore germination
L2Z07_03515	COG3121	Chaperone
L2Z07_03520	COG3539	Fimbrial protein
L2Z07_03545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z07_03545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z07_03595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z07_03605	COG2353	YceI-like domain
L2Z07_03615	COG3698	Phosphodiester glycosidase
L2Z07_03630	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z07_03635	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z07_03635	COG0506	proline dehydrogenase activity
L2Z07_03635	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z07_03645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z07_03650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z07_03670	COG1132	(ABC) transporter
L2Z07_03675	COG3122	Protein conserved in bacteria
L2Z07_03680	COG3619	membrane
L2Z07_03690	COG0640	Transcriptional regulator
L2Z07_03700	COG2850	peptidyl-arginine hydroxylation
L2Z07_03705	COG0424	maF-like protein
L2Z07_03725	COG0191	fructose-bisphosphate aldolase activity
L2Z07_03730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z07_03745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z07_03755	COG1192	Involved in chromosome partitioning
L2Z07_03760	COG1475	DNA binding
L2Z07_03765	COG0811	peptide transport
L2Z07_03775	COG1132	(ABC) transporter
L2Z07_03780	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z07_03800	COG0084	hydrolase, TatD family'
L2Z07_03865	COG0776	regulation of translation
L2Z07_03895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z07_03900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z07_03925	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
L2Z07_03945	COG0339	signal peptide processing
L2Z07_03955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z07_03990	COG0702	epimerase
L2Z07_03995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z07_04015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z07_04045	COG0316	Belongs to the HesB IscA family
L2Z07_04050	COG0822	iron-sulfur transferase activity
L2Z07_04075	COG0776	regulation of translation
L2Z07_04080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z07_04085	COG2207	Transcriptional regulator
L2Z07_04090	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z07_04095	COG1960	acyl-CoA dehydrogenase activity
L2Z07_04100	COG1960	acyl-CoA dehydrogenase activity
L2Z07_04115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z07_04130	COG2814	Major facilitator Superfamily
L2Z07_04135	COG4264	IucA IucC family
L2Z07_04140	COG4264	IucA IucC family
L2Z07_04150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z07_04180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z07_04195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z07_04200	COG0406	alpha-ribazole phosphatase activity
L2Z07_04215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z07_04220	COG0730	response to heat
L2Z07_04240	COG4773	Receptor
L2Z07_04245	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z07_04300	COG2226	methyltransferase
L2Z07_04325	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z07_04365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z07_04375	COG0133	tryptophan synthase activity
L2Z07_04390	COG3706	GGDEF domain
L2Z07_04405	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z07_04410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z07_04415	COG0022	dehydrogenase e1 component
L2Z07_04420	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z07_04425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z07_04435	COG1063	alcohol dehydrogenase
L2Z07_04440	COG3781	membrane
L2Z07_04450	COG3453	Protein conserved in bacteria
L2Z07_04450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z07_04465	COG0730	response to heat
L2Z07_04480	COG3708	Transcriptional regulator
L2Z07_04480	COG2207	Transcriptional regulator
L2Z07_04485	COG1733	regulation of RNA biosynthetic process
L2Z07_04490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z07_04500	COG2188	Transcriptional regulator
L2Z07_04515	COG4521	taurine ABC transporter
L2Z07_04520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z07_04540	COG0477	Major facilitator Superfamily
L2Z07_04565	COG0583	DNA-binding transcription factor activity
L2Z07_04570	COG0583	DNA-binding transcription factor activity
L2Z07_04575	COG0183	Belongs to the thiolase family
L2Z07_04580	COG2031	fatty acid transporter
L2Z07_04595	COG0583	DNA-binding transcription factor activity
L2Z07_04605	COG2610	gluconate transmembrane transporter activity
L2Z07_04610	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_04615	COG2207	Transcriptional regulator
L2Z07_04630	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_04640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z07_04655	COG0543	2 iron, 2 sulfur cluster binding
L2Z07_04655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z07_04660	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z07_04665	COG4638	Rieske (2fe-2S)
L2Z07_04675	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z07_04680	COG4149	molybdate abc transporter
L2Z07_04685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z07_04690	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_04695	COG1535	isochorismatase
L2Z07_04695	COG3433	isochorismatase activity
L2Z07_04760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z07_04775	COG0753	catalase activity
L2Z07_04785	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z07_04815	COG3539	Fimbrial protein
L2Z07_05045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z07_05055	COG2072	flavoprotein involved in K transport
L2Z07_05065	COG1538	Outer membrane efflux protein
L2Z07_05070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z07_05075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z07_05080	COG0745	RESPONSE REGULATOR receiver
L2Z07_05085	COG2205	protein histidine kinase activity
L2Z07_05095	COG2207	Transcriptional regulator
L2Z07_05110	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_05120	COG1073	alpha beta
L2Z07_05155	COG0556	nucleotide-excision repair
L2Z07_05170	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z07_05230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z07_05245	COG2084	Dehydrogenase
L2Z07_05255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z07_05260	COG0583	DNA-binding transcription factor activity
L2Z07_05270	COG0129	dihydroxy-acid dehydratase activity
L2Z07_05275	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_05290	COG1566	PFAM secretion protein HlyD family protein
L2Z07_05305	COG0583	DNA-binding transcription factor activity
L2Z07_05320	COG2188	Transcriptional regulator
L2Z07_05380	COG1473	amidohydrolase
L2Z07_05390	COG0475	glutathione-regulated potassium exporter activity
L2Z07_05390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z07_05400	COG0583	DNA-binding transcription factor activity
L2Z07_05405	COG1335	isochorismatase
L2Z07_05425	COG1902	pentaerythritol trinitrate reductase activity
L2Z07_05435	COG4689	acetoacetate decarboxylase
L2Z07_05440	COG4221	oxidoreductase activity
L2Z07_05450	COG1309	transcriptional regulator
L2Z07_05490	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z07_05490	COG1902	pentaerythritol trinitrate reductase activity
L2Z07_05505	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_05525	COG2186	Transcriptional regulator
L2Z07_05535	COG0583	DNA-binding transcription factor activity
L2Z07_05540	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z07_05545	COG4829	muconolactone delta-isomerase
L2Z07_05555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z07_05560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z07_05565	COG0183	Belongs to the thiolase family
L2Z07_05570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z07_05580	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_05600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z07_05610	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_05620	COG4638	Rieske (2fe-2S)
L2Z07_05640	COG0154	amidase activity
L2Z07_05650	COG2814	Major facilitator Superfamily
L2Z07_05675	COG1960	acyl-CoA dehydrogenase activity
L2Z07_05680	COG0583	DNA-binding transcription factor activity
L2Z07_05685	COG1414	Transcriptional regulator
L2Z07_05700	COG2391	methyltransferase activity
L2Z07_05710	COG4993	Dehydrogenase
L2Z07_05715	COG3659	wide pore channel activity
L2Z07_05720	COG3420	alginic acid biosynthetic process
L2Z07_05725	COG0710	3-dehydroquinate dehydratase activity
L2Z07_05730	COG3485	protocatechuate 3,4-dioxygenase
L2Z07_05735	COG3485	protocatechuate 3,4-dioxygenase
L2Z07_05740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z07_05745	COG2271	Major facilitator Superfamily
L2Z07_05750	COG0596	Alpha beta hydrolase
L2Z07_05755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z07_05760	COG0183	Belongs to the thiolase family
L2Z07_05765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z07_05770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z07_05780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z07_05785	COG2323	membrane
L2Z07_05830	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z07_05830	COG1902	pentaerythritol trinitrate reductase activity
L2Z07_05855	COG0542	response to heat
L2Z07_05860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z07_05890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z07_05895	COG0569	domain protein
L2Z07_05900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z07_05915	COG4774	siderophore transport
L2Z07_05920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z07_05930	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z07_05950	COG1294	oxidase, subunit
L2Z07_05955	COG4890	Cyd operon protein YbgT
L2Z07_05965	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z07_05975	COG0552	protein localization to endoplasmic reticulum
L2Z07_06000	COG0516	GMP reductase activity
L2Z07_06000	COG0517	IMP dehydrogenase activity
L2Z07_06005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z07_06010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z07_06020	COG0583	DNA-binding transcription factor activity
L2Z07_06025	COG0024	Methionine aminopeptidase
L2Z07_06055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z07_06055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z07_06060	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z07_06065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z07_06065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z07_06065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z07_06085	COG5001	Diguanylate cyclase
L2Z07_06085	COG3300	MHYT domain
L2Z07_06100	COG2135	peptidase activity
L2Z07_06105	COG0659	secondary active sulfate transmembrane transporter activity
L2Z07_06125	COG1113	amino acid transport
L2Z07_06135	COG1522	sequence-specific DNA binding
L2Z07_06160	COG1011	Hydrolase
L2Z07_06165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z07_06175	COG2137	regulation of response to DNA damage stimulus
L2Z07_06190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z07_06225	COG0575	Belongs to the CDS family
L2Z07_06230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z07_06255	COG3852	Histidine kinase
L2Z07_06260	COG2204	response regulator
L2Z07_06315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z07_06320	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z07_06340	COG0697	spore germination
L2Z07_06355	COG0303	'Molybdopterin
L2Z07_06360	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z07_06360	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z07_06375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z07_06380	COG0243	molybdopterin cofactor binding
L2Z07_06390	COG0243	molybdopterin cofactor binding
L2Z07_06395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z07_06400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z07_06400	COG2146	nitrite reductase [NAD(P)H] activity
L2Z07_06410	COG0745	RESPONSE REGULATOR receiver
L2Z07_06415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z07_06415	COG1116	anion transmembrane transporter activity
L2Z07_06435	COG0511	ligase activity, forming carbon-carbon bonds
L2Z07_06450	COG2814	Major facilitator Superfamily
L2Z07_06470	COG0069	glutamate synthase activity
L2Z07_06490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z07_06500	COG1454	alcohol dehydrogenase
L2Z07_06505	COG0824	Thioesterase
L2Z07_06515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z07_06530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z07_06535	COG2030	dehydratase
L2Z07_06545	COG0183	Belongs to the thiolase family
L2Z07_06555	COG0583	DNA-binding transcription factor activity
L2Z07_06560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z07_06570	COG1522	sequence-specific DNA binding
L2Z07_06575	COG3135	benzoate transporter
L2Z07_06585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z07_06605	COG0589	response to stress
L2Z07_06610	COG0488	(ABC) transporter
L2Z07_06630	COG4773	Receptor
L2Z07_06660	COG0668	transmembrane transport
L2Z07_06670	COG1309	transcriptional regulator
L2Z07_06680	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
L2Z07_06695	COG1605	Chorismate mutase
L2Z07_06735	COG0308	aminopeptidase N
L2Z07_06760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z07_06765	COG1454	alcohol dehydrogenase
L2Z07_06785	COG0531	amino acid
L2Z07_06790	COG4303	Ethanolamine ammonia lyase large subunit
L2Z07_06795	COG4302	ethanolamine ammonia-lyase activity
L2Z07_06800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z07_06800	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z07_06805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z07_06830	COG0697	spore germination
L2Z07_06835	COG1923	regulation of RNA biosynthetic process
L2Z07_06845	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z07_06850	COG0802	atpase or kinase
L2Z07_06870	COG1187	pseudouridine synthase activity
L2Z07_06885	COG0583	DNA-binding transcription factor activity
L2Z07_06900	COG2814	Major facilitator Superfamily
L2Z07_06905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z07_06930	COG0729	surface antigen
L2Z07_06950	COG0174	glutamine synthetase
L2Z07_06955	COG0745	RESPONSE REGULATOR receiver
L2Z07_06960	COG2205	protein histidine kinase activity
L2Z07_06970	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z07_06975	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z07_07000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z07_07005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z07_07010	COG1960	acyl-CoA dehydrogenase activity
L2Z07_07025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z07_07030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z07_07050	COG0583	DNA-binding transcription factor activity
L2Z07_07065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z07_07075	COG3658	cytochrome
L2Z07_07080	COG1215	transferase activity, transferring glycosyl groups
L2Z07_07085	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z07_07085	COG0726	polysaccharide deacetylase
L2Z07_07110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z07_07115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z07_07125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z07_07150	COG0305	Participates in initiation and elongation during chromosome replication
L2Z07_07155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z07_07165	COG1305	Transglutaminase-like
L2Z07_07175	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z07_07205	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z07_07210	COG0138	bifunctional purine biosynthesis protein purh
L2Z07_07215	COG0151	Belongs to the GarS family
L2Z07_07220	COG1464	Belongs to the NlpA lipoprotein family
L2Z07_07225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z07_07230	COG2011	ABC-type metal ion transport system permease component
L2Z07_07235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z07_07245	COG1301	dicarboxylic acid transport
L2Z07_07275	COG1794	racemase activity, acting on amino acids and derivatives
L2Z07_07285	COG3008	intermembrane lipid transfer
L2Z07_07285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z07_07290	COG2995	paraquat-inducible protein a
L2Z07_07300	COG2826	transposase and inactivated derivatives, IS30 family
L2Z07_07305	COG2985	domain, Protein
L2Z07_07335	COG0477	Major facilitator Superfamily
L2Z07_07385	COG2186	Transcriptional regulator
L2Z07_07395	COG0786	glutamate:sodium symporter activity
L2Z07_07400	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z07_07425	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z07_07525	COG1610	YqeY-like protein
L2Z07_07530	COG4783	chaperone-mediated protein folding
L2Z07_07555	COG1286	toxin biosynthetic process
L2Z07_07585	COG0778	Nitroreductase
L2Z07_07595	COG0513	Belongs to the DEAD box helicase family
L2Z07_07620	COG2363	Small membrane protein
L2Z07_07645	COG1234	tRNA 3'-trailer cleavage
L2Z07_07650	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z07_07660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z07_07670	COG2819	hydrolase of the alpha beta superfamily
L2Z07_07675	COG1960	acyl-CoA dehydrogenase activity
L2Z07_07680	COG1301	dicarboxylic acid transport
L2Z07_07685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z07_07690	COG3139	Protein of unknown function (DUF1315)
L2Z07_07695	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z07_07700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z07_07710	COG0494	nUDIX hydrolase
L2Z07_07720	COG0642	Histidine kinase
L2Z07_07735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z07_07745	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z07_07760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z07_07765	COG0826	peptidase U32
L2Z07_07770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z07_07785	COG4160	amino acid transport
L2Z07_07790	COG4215	(ABC) transporter
L2Z07_07805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z07_07850	COG1131	(ABC) transporter
L2Z07_07855	COG0842	Transport permease protein
L2Z07_07870	COG0772	Belongs to the SEDS family
L2Z07_07875	COG2951	lytic endotransglycosylase activity
L2Z07_07900	COG2207	Transcriptional regulator
L2Z07_07915	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z07_07920	COG0024	Methionine aminopeptidase
L2Z07_07930	COG2223	nitrite transmembrane transporter activity
L2Z07_07940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z07_07945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z07_07950	COG1960	acyl-CoA dehydrogenase activity
L2Z07_07965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z07_07970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z07_07975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z07_07995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z07_08000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z07_08005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z07_08040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z07_08050	COG0174	glutamine synthetase
L2Z07_08065	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z07_08120	COG0302	gtp cyclohydrolase
L2Z07_08145	COG3739	integral membrane protein
L2Z07_08160	COG1169	isochorismate synthase
L2Z07_08170	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z07_08175	COG1132	(ABC) transporter
L2Z07_08180	COG1132	(ABC) transporter
L2Z07_08190	COG1535	isochorismatase
L2Z07_08190	COG3433	isochorismatase activity
L2Z07_08195	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z07_08200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z07_08210	COG4774	siderophore transport
L2Z07_08215	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z07_08220	COG4604	ABC transporter, ATP-binding protein
L2Z07_08225	COG4605	iron ion homeostasis
L2Z07_08230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z07_08235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z07_08250	COG2964	Protein conserved in bacteria
L2Z07_08260	COG1741	Belongs to the pirin family
L2Z07_08320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z07_08320	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z07_08325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z07_08335	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_08345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z07_08350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z07_08355	COG0006	proline dipeptidase activity
L2Z07_08360	COG0583	DNA-binding transcription factor activity
L2Z07_08370	COG2879	small protein
L2Z07_08375	COG1966	Carbon starvation protein
L2Z07_08395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
L2Z07_08420	COG1067	ATP-dependent peptidase activity
L2Z07_08425	COG0583	DNA-binding transcription factor activity
L2Z07_08450	COG1686	Belongs to the peptidase S11 family
L2Z07_08455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z07_08490	COG0616	signal peptide processing
L2Z07_08495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z07_08505	COG0573	inorganic phosphate transmembrane transporter activity
L2Z07_08510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z07_08515	COG1113	amino acid transport
L2Z07_08520	COG3961	Belongs to the TPP enzyme family
L2Z07_08525	COG1522	sequence-specific DNA binding
L2Z07_08535	COG0076	glutamate decarboxylase activity
L2Z07_08540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z07_08550	COG1309	transcriptional regulator
L2Z07_08565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z07_08600	COG0352	thiamine-phosphate diphosphorylase activity
L2Z07_08625	COG1203	CRISPR-associated helicase, Cas3
L2Z07_08655	COG0612	Peptidase, M16
L2Z07_08665	COG1823	symporter activity
L2Z07_08670	COG0583	DNA-binding transcription factor activity
L2Z07_08675	COG0477	Major facilitator Superfamily
L2Z07_08695	COG1187	pseudouridine synthase activity
L2Z07_08710	COG1686	Belongs to the peptidase S11 family
L2Z07_08715	COG1252	NADH dehydrogenase
L2Z07_08725	COG0415	Belongs to the DNA photolyase family
L2Z07_08740	COG1215	transferase activity, transferring glycosyl groups
L2Z07_08770	COG2070	2-Nitropropane dioxygenase
L2Z07_08825	COG0556	nucleotide-excision repair
L2Z07_08845	COG0436	Aminotransferase
L2Z07_08875	COG4221	oxidoreductase activity
L2Z07_08885	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z07_08890	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z07_08900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z07_08915	COG0681	Belongs to the peptidase S26 family
L2Z07_08930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z07_08950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z07_08955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z07_08960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z07_08970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z07_08975	COG4208	sulfate ABC transporter
L2Z07_08980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z07_08985	COG0583	DNA-binding transcription factor activity
L2Z07_08990	COG4625	pathogenesis
L2Z07_09005	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z07_09020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z07_09030	COG1051	belongs to the nudix hydrolase family
L2Z07_09030	COG1056	cytidyltransferase-related domain
L2Z07_09035	COG1024	Enoyl-CoA hydratase
L2Z07_09045	COG2814	Major facilitator Superfamily
L2Z07_09050	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z07_09050	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z07_09070	COG1473	amidohydrolase
L2Z07_09075	COG0824	Thioesterase
L2Z07_09095	COG0823	Involved in the tonB-independent uptake of proteins
L2Z07_09115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z07_09150	COG0628	permease
L2Z07_09160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z07_09165	COG0596	Alpha beta hydrolase
L2Z07_09170	COG0616	signal peptide processing
L2Z07_09170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z07_09180	COG0658	competence protein
L2Z07_09180	COG2333	competence protein COMEC
L2Z07_09185	COG1136	(ABC) transporter
L2Z07_09190	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z07_09225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z07_09245	COG0463	Glycosyl transferase, family 2
L2Z07_09275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z07_09280	COG1280	lysine exporter protein (LysE YggA)
L2Z07_09285	COG2267	carboxylic ester hydrolase activity
L2Z07_09295	COG0019	diaminopimelate decarboxylase activity
L2Z07_09305	COG1113	amino acid transport
L2Z07_09320	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z07_09335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z07_09340	COG0243	molybdopterin cofactor binding
L2Z07_09345	COG1929	Belongs to the glycerate kinase type-1 family
L2Z07_09360	COG0778	Nitroreductase
L2Z07_09400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z07_09420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z07_09440	COG0741	lytic transglycosylase activity
L2Z07_09460	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z07_09465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z07_09490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z07_09495	COG1597	lipid kinase activity
L2Z07_09510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z07_09515	COG0477	Major facilitator Superfamily
L2Z07_09565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z07_09570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z07_09595	COG0505	Belongs to the CarA family
L2Z07_09615	COG0589	response to stress
L2Z07_09630	COG2843	Capsule synthesis protein
L2Z07_09655	COG2321	neutral zinc metallopeptidase
L2Z07_09660	COG2354	Protein conserved in bacteria
L2Z07_09695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z07_09720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z07_09725	COG1053	succinate dehydrogenase
L2Z07_09730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z07_09735	COG2009	succinate dehydrogenase
L2Z07_09770	COG2921	Belongs to the UPF0250 family
L2Z07_09775	COG0321	lipoyl(octanoyl) transferase activity
L2Z07_09790	COG0531	amino acid
L2Z07_09800	COG1733	regulation of RNA biosynthetic process
L2Z07_09805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z07_09810	COG1648	precorrin-2 dehydrogenase activity
L2Z07_09810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z07_09825	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z07_09855	COG0671	phosphoesterase, PA-phosphatase related
L2Z07_09860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z07_09870	COG1538	Outer membrane efflux protein
L2Z07_09875	COG0393	Putative heavy-metal-binding
L2Z07_09880	COG0393	Putative heavy-metal-binding
L2Z07_09890	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_09900	COG0525	valine-tRNA ligase activity
L2Z07_09920	COG0583	DNA-binding transcription factor activity
L2Z07_09925	COG0004	ammonium transporteR
L2Z07_09935	COG0642	Histidine kinase
L2Z07_09940	COG0745	RESPONSE REGULATOR receiver
L2Z07_09945	COG2194	sulfuric ester hydrolase activity
L2Z07_09965	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z07_09980	COG2315	Protein conserved in bacteria
L2Z07_09985	COG0142	geranyltranstransferase activity
L2Z07_09990	COG2828	Protein conserved in bacteria
L2Z07_09995	COG1113	amino acid transport
L2Z07_10005	COG0582	viral genome integration into host DNA
L2Z07_10425	COG2207	Transcriptional regulator
L2Z07_10450	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z07_10460	COG0560	Phosphoserine phosphatase
L2Z07_10470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z07_10480	COG1530	ribonuclease E activity
L2Z07_10485	COG0424	maF-like protein
L2Z07_10490	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z07_10495	COG1792	Involved in formation and maintenance of cell shape
L2Z07_10500	COG1077	Cell shape determining protein MreB Mrl
L2Z07_10505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z07_10515	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z07_10540	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z07_10545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z07_10550	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z07_10555	COG1115	amino acid carrier protein
L2Z07_10575	COG2814	Major facilitator Superfamily
L2Z07_10580	COG1289	transmembrane transporter activity
L2Z07_10590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z07_10630	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z07_10635	COG2832	Protein of unknown function (DUF454)
L2Z07_10645	COG5510	response to toxic substance
L2Z07_10660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z07_10675	COG0840	transmembrane signaling receptor activity
L2Z07_10715	COG3422	double-strand break repair
L2Z07_10720	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z07_10725	COG3189	MarR family transcriptional regulator
L2Z07_10735	COG0354	folic acid binding
L2Z07_10740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z07_10750	COG0679	Auxin Efflux Carrier
L2Z07_10755	COG1902	pentaerythritol trinitrate reductase activity
L2Z07_10760	COG4772	TonB-dependent receptor
L2Z07_10765	COG2094	Belongs to the DNA glycosylase MPG family
L2Z07_10790	COG1217	gtp-binding protein TYPA
L2Z07_10795	COG2233	PERMEase
L2Z07_10805	COG0833	amino acid
L2Z07_10810	COG1690	Belongs to the RtcB family
L2Z07_10820	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z07_10820	COG2885	chlorophyll binding
L2Z07_10830	COG0183	Belongs to the thiolase family
L2Z07_10850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z07_10870	COG2207	Transcriptional regulator
L2Z07_10875	COG0183	Belongs to the thiolase family
L2Z07_10895	COG2153	protein acetylation
L2Z07_10905	COG1272	protein, Hemolysin III
L2Z07_10925	COG0450	alkyl hydroperoxide reductase
L2Z07_10945	COG0285	dihydrofolate synthase activity
L2Z07_10995	COG2096	Adenosyltransferase
L2Z07_11015	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z07_11020	COG0745	RESPONSE REGULATOR receiver
L2Z07_11025	COG2205	protein histidine kinase activity
L2Z07_11035	COG1960	acyl-CoA dehydrogenase activity
L2Z07_11040	COG1960	acyl-CoA dehydrogenase activity
L2Z07_11105	COG0438	transferase activity, transferring glycosyl groups
L2Z07_11110	COG0463	Glycosyl transferase, family 2
L2Z07_11115	COG0726	polysaccharide deacetylase
L2Z07_11135	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z07_11140	COG2205	protein histidine kinase activity
L2Z07_11170	COG1862	Preprotein translocase
L2Z07_11185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z07_11195	COG3781	membrane
L2Z07_11200	COG0613	PHP domain protein
L2Z07_11210	COG2350	Protein conserved in bacteria
L2Z07_11240	COG1607	acyl-coa hydrolase
L2Z07_11305	COG2199	diguanylate cyclase activity
L2Z07_11315	COG1408	metallophosphoesterase
L2Z07_11320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z07_11330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z07_11350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z07_11355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z07_11370	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z07_11380	COG2969	positive regulation of protein catabolic process
L2Z07_11400	COG1960	acyl-CoA dehydrogenase activity
L2Z07_11405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z07_11420	COG1309	transcriptional regulator
L2Z07_11425	COG1960	acyl-CoA dehydrogenase activity
L2Z07_11470	COG1183	phosphatidylcholine synthase activity
L2Z07_11475	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z07_11505	COG0739	heme binding
L2Z07_11505	COG1196	nuclear chromosome segregation
L2Z07_11505	COG0741	lytic transglycosylase activity
L2Z07_11515	COG1702	phosphate starvation-inducible protein PhoH
L2Z07_11550	COG1295	ribonuclease BN
L2Z07_11555	COG0697	spore germination
L2Z07_11560	COG2169	Transcriptional regulator
L2Z07_11565	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z07_11610	COG0557	exoribonuclease II activity
L2Z07_11615	COG0339	signal peptide processing
L2Z07_11620	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z07_11650	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z07_11655	COG1960	acyl-CoA dehydrogenase activity
L2Z07_11810	COG0626	cystathionine gamma-synthase activity
L2Z07_11815	COG0433	COG0433 Predicted ATPase
L2Z07_11820	COG1017	nitric oxide dioxygenase activity
L2Z07_11820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z07_11825	COG1959	2 iron, 2 sulfur cluster binding
L2Z07_11840	COG1301	dicarboxylic acid transport
L2Z07_11845	COG1946	Acyl-CoA thioesterase
L2Z07_11865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z07_11870	COG1040	competence protein
L2Z07_11875	COG0494	nUDIX hydrolase
L2Z07_11885	COG0598	Magnesium transport protein CorA
L2Z07_11895	COG2854	intermembrane phospholipid transfer
L2Z07_11905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z07_11910	COG1127	ABC transporter
L2Z07_11920	COG0513	Belongs to the DEAD box helicase family
L2Z07_11940	COG0408	coproporphyrinogen oxidase activity
L2Z07_11955	COG1960	acyl-CoA dehydrogenase activity
L2Z07_11965	COG1983	PspC domain protein
L2Z07_11970	COG0517	IMP dehydrogenase activity
L2Z07_12020	COG0583	DNA-binding transcription factor activity
L2Z07_12060	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_12070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z07_12075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z07_12080	COG0833	amino acid
L2Z07_12110	COG1192	Involved in chromosome partitioning
L2Z07_12115	COG0628	permease
L2Z07_12125	COG1289	transmembrane transporter activity
L2Z07_12140	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z07_12145	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z07_12155	COG0277	FAD linked oxidase domain protein
L2Z07_12160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z07_12195	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z07_12200	COG5380	lipid catabolic process
L2Z07_12220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z07_12270	COG0194	GDP metabolic process
L2Z07_12285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z07_12305	COG3307	-O-antigen
L2Z07_12320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z07_12325	COG1704	LemA family
L2Z07_12335	COG0493	'glutamate synthase
L2Z07_12340	COG0067	glutamate synthase
L2Z07_12340	COG0069	glutamate synthase activity
L2Z07_12340	COG0070	glutamate synthase
L2Z07_12390	COG2226	methyltransferase
L2Z07_12405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z07_12410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z07_12455	COG0833	amino acid
L2Z07_12520	COG0488	(ABC) transporter
L2Z07_12525	COG2873	o-acetylhomoserine
L2Z07_12530	COG4221	oxidoreductase activity
L2Z07_12535	COG0659	secondary active sulfate transmembrane transporter activity
L2Z07_12560	COG0427	acetyl-CoA hydrolase
L2Z07_12590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z07_12630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z07_12690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2Z07_12700	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z07_12705	COG1733	regulation of RNA biosynthetic process
L2Z07_12720	COG1733	regulation of RNA biosynthetic process
L2Z07_12740	COG0667	Aldo Keto reductase
L2Z07_12760	COG0583	DNA-binding transcription factor activity
L2Z07_12765	COG2814	Major facilitator Superfamily
L2Z07_12795	COG1335	isochorismatase
L2Z07_12805	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_12810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z07_12820	COG1113	amino acid transport
L2Z07_12830	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z07_12845	COG2814	Major facilitator Superfamily
L2Z07_12855	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z07_12855	COG0351	phosphomethylpyrimidine kinase
L2Z07_12855	COG0352	thiamine-phosphate diphosphorylase activity
L2Z07_12875	COG1309	transcriptional regulator
L2Z07_12880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z07_12895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z07_12905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z07_12910	COG3162	membrane
L2Z07_12915	COG0784	Response regulator, receiver
L2Z07_12915	COG2198	Histidine kinase
L2Z07_12915	COG2205	protein histidine kinase activity
L2Z07_12940	COG1522	sequence-specific DNA binding
L2Z07_12945	COG1335	isochorismatase
L2Z07_12950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z07_12960	COG0668	transmembrane transport
L2Z07_12965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z07_12970	COG1519	Transferase
L2Z07_12975	COG1902	pentaerythritol trinitrate reductase activity
L2Z07_12995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z07_13020	COG0426	domain, Protein
L2Z07_13020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z07_13025	COG4774	siderophore transport
L2Z07_13030	COG2119	membrane
L2Z07_13040	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z07_13050	COG4942	peptidase
L2Z07_13065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z07_13075	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z07_13095	COG0189	ligase activity
L2Z07_13115	COG0708	Exodeoxyribonuclease III
L2Z07_13120	COG1393	Belongs to the ArsC family
L2Z07_13135	COG3706	GGDEF domain
L2Z07_13170	COG2351	hydroxyisourate hydrolase activity
L2Z07_13175	COG2233	PERMEase
L2Z07_13185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z07_13195	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z07_13205	COG3150	esterase
L2Z07_13275	COG2918	glutathione biosynthetic process
L2Z07_13290	COG2733	membrane
L2Z07_13295	COG0436	Aminotransferase
L2Z07_13300	COG0534	Mate efflux family protein
L2Z07_13385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z07_13390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z07_13400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z07_13465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z07_13475	COG0534	Mate efflux family protein
L2Z07_13490	COG4774	siderophore transport
L2Z07_13495	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z07_13515	COG0019	diaminopimelate decarboxylase activity
L2Z07_13520	COG3486	L-lysine 6-monooxygenase (NADPH) activity
L2Z07_13525	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z07_13530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z07_13545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z07_13550	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_13560	COG1169	isochorismate synthase
L2Z07_13585	COG0084	hydrolase, TatD family'
L2Z07_13620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z07_13635	COG0010	Belongs to the arginase family
L2Z07_13665	COG2188	Transcriptional regulator
L2Z07_13675	COG0523	cobalamin synthesis protein
L2Z07_13685	COG1113	amino acid transport
L2Z07_13695	COG0625	glutathione transferase activity
L2Z07_13715	COG1683	Conserved Protein
L2Z07_13720	COG0534	Mate efflux family protein
L2Z07_13730	COG1335	isochorismatase
L2Z07_13735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z07_13755	COG2116	formate transmembrane transporter activity
L2Z07_13760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z07_13765	COG2133	pyrroloquinoline quinone binding
L2Z07_13770	COG2983	Belongs to the UPF0260 family
L2Z07_13790	COG1194	a g-specific adenine glycosylase
L2Z07_13805	COG2818	Glycosylase
L2Z07_13810	COG1064	alcohol dehydrogenase
L2Z07_13815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z07_13830	COG0583	DNA-binding transcription factor activity
L2Z07_13835	COG0656	L-ascorbic acid biosynthetic process
L2Z07_13840	COG2814	Major facilitator Superfamily
L2Z07_13875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z07_13890	COG2233	PERMEase
L2Z07_13895	COG0583	DNA-binding transcription factor activity
L2Z07_13930	COG0733	neurotransmitter:sodium symporter activity
L2Z07_13970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z07_13975	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z07_13980	COG0596	Alpha beta hydrolase
L2Z07_14005	COG0488	(ABC) transporter
L2Z07_14010	COG0586	Pfam SNARE associated Golgi protein
L2Z07_14020	COG0187	DNA topoisomerase II activity
L2Z07_14030	COG0592	DNA-directed DNA polymerase activity
L2Z07_14055	COG0706	membrane insertase activity
L2Z07_14070	COG1230	cation diffusion facilitator family transporter
L2Z07_14075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z07_14090	COG0402	S-adenosylhomocysteine deaminase activity
L2Z07_14100	COG0754	glutathionylspermidine amidase activity
L2Z07_14110	COG0861	Integral membrane protein TerC family
L2Z07_14115	COG0671	phosphoesterase, PA-phosphatase related
L2Z07_14125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z07_14140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z07_14145	COG2951	lytic endotransglycosylase activity
L2Z07_14175	COG0583	DNA-binding transcription factor activity
L2Z07_14195	COG0657	acetylesterase activity
L2Z07_14200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z07_14250	COG1047	Peptidyl-prolyl cis-trans
L2Z07_14260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z07_14265	COG0196	riboflavin kinase activity
L2Z07_14275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z07_14280	COG1309	transcriptional regulator
L2Z07_14285	COG1116	anion transmembrane transporter activity
L2Z07_14290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z07_14295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z07_14300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z07_14305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z07_14325	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_14330	COG0546	phosphoglycolate phosphatase activity
L2Z07_14355	COG1017	nitric oxide dioxygenase activity
L2Z07_14355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z07_14390	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z07_14395	COG0728	peptidoglycan biosynthetic process
L2Z07_14430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z07_14450	COG0438	transferase activity, transferring glycosyl groups
L2Z07_14460	COG0438	transferase activity, transferring glycosyl groups
L2Z07_14465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z07_14475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L2Z07_14485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z07_14500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z07_14505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z07_14515	COG2186	Transcriptional regulator
L2Z07_14525	COG0277	FAD linked oxidase domain protein
L2Z07_14530	COG1448	Aminotransferase
L2Z07_14535	COG1802	Transcriptional regulator
L2Z07_14550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z07_14580	COG3328	transposase activity
L2Z07_14595	COG0564	pseudouridine synthase activity
L2Z07_14635	COG0251	oxidation-reduction process
L2Z07_14640	COG1113	amino acid transport
L2Z07_14645	COG1113	amino acid transport
L2Z07_14665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z07_14670	COG1960	acyl-CoA dehydrogenase activity
L2Z07_14675	COG1024	Enoyl-CoA hydratase
L2Z07_14680	COG1024	Enoyl-CoA hydratase
L2Z07_14685	COG0477	Major facilitator Superfamily
L2Z07_14690	COG3916	Acyl-homoserine-lactone synthase
L2Z07_14700	COG2197	response regulator
L2Z07_14710	COG1960	acyl-CoA dehydrogenase activity
L2Z07_14715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z07_14715	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z07_14715	COG3321	synthase
L2Z07_14715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z07_14735	COG2267	carboxylic ester hydrolase activity
L2Z07_14755	COG0271	Belongs to the BolA IbaG family
L2Z07_14765	COG1192	Involved in chromosome partitioning
L2Z07_14780	COG0586	Pfam SNARE associated Golgi protein
L2Z07_14785	COG2259	Doxx family
L2Z07_14790	COG4399	Belongs to the UPF0754 family
L2Z07_14795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z07_14795	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z07_14840	COG0281	malic enzyme
L2Z07_14845	COG2837	iron assimilation
L2Z07_14850	COG1280	lysine exporter protein (LysE YggA)
L2Z07_14855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z07_14860	COG1121	(ABC) transporter
L2Z07_14925	COG0386	Belongs to the glutathione peroxidase family
L2Z07_14940	COG1309	transcriptional regulator
L2Z07_14945	COG0697	spore germination
L2Z07_14955	COG0758	DNA mediated transformation
L2Z07_15025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z07_15035	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z07_15075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z07_15085	COG0477	Major facilitator Superfamily
L2Z07_15095	COG1253	flavin adenine dinucleotide binding
L2Z07_15100	COG3012	SEC-C Motif Domain Protein
L2Z07_15105	COG2860	membrane
L2Z07_15110	COG0477	Major facilitator Superfamily
L2Z07_15120	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z07_15135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z07_15155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z07_15200	COG2072	flavoprotein involved in K transport
L2Z07_15205	COG0492	ferredoxin-NADP+ reductase activity
L2Z07_15210	COG0431	NADPH-dependent FMN reductase
L2Z07_15215	COG0798	PFAM Bile acid sodium symporter
L2Z07_15225	COG0640	Transcriptional regulator
L2Z07_15240	COG0789	Transcriptional regulator
L2Z07_15265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L2Z07_15350	COG0789	Transcriptional regulator
L2Z07_15370	COG0697	spore germination
L2Z07_15425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2Z07_15525	COG0789	Transcriptional regulator
L2Z07_15550	COG0659	secondary active sulfate transmembrane transporter activity
L2Z07_15570	COG0347	Belongs to the P(II) protein family
L2Z07_15575	COG0004	ammonium transporteR
L2Z07_15585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z07_15585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z07_15625	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z07_15630	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z07_15635	COG0793	Belongs to the peptidase S41A family
L2Z07_15650	COG2197	response regulator
L2Z07_15660	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z07_15670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z07_15675	COG4974	Belongs to the 'phage' integrase family
L2Z07_15700	COG0772	Belongs to the SEDS family
L2Z07_15705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z07_15710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z07_15715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z07_15740	COG0697	spore germination
L2Z07_15745	COG1538	Outer membrane efflux protein
L2Z07_15765	COG3275	phosphorelay sensor kinase activity
L2Z07_15775	COG0181	hydroxymethylbilane synthase activity
L2Z07_15820	COG1716	ATPase activity
L2Z07_15825	COG0546	phosphoglycolate phosphatase activity
L2Z07_15925	COG2056	Na+-H+ antiporter family
L2Z07_15940	COG0326	Molecular chaperone. Has ATPase activity
L2Z07_15955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z07_16015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z07_16020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z07_16020	COG2169	Transcriptional regulator
L2Z07_16050	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z07_16060	COG0497	DNA recombination
L2Z07_16075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z07_16085	COG0237	dephospho-CoA kinase activity
L2Z07_16090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z07_16140	COG0195	Participates in both transcription termination and antitermination
L2Z07_16155	COG1320	monovalent cation:proton antiporter activity
L2Z07_16160	COG2212	antiporter activity
L2Z07_16165	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z07_16170	COG0651	ATP synthesis coupled electron transport
L2Z07_16175	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z07_16180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z07_16180	COG2111	Na H antiporter
L2Z07_16195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z07_16200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z07_16215	COG2226	methyltransferase
L2Z07_16235	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z07_16240	COG1074	ATP-dependent DNA helicase activity
L2Z07_16245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z07_16250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z07_16265	COG0598	Magnesium transport protein CorA
L2Z07_16270	COG0789	Transcriptional regulator
L2Z07_16275	COG0484	heat shock protein binding
L2Z07_16290	COG0475	glutathione-regulated potassium exporter activity
L2Z07_16290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z07_16295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z07_16315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z07_16325	COG4535	Mg2 and Co2 transporter CorC
L2Z07_16330	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z07_16340	COG0644	oxidoreductase
L2Z07_16340	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z07_16350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z07_16365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z07_16370	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z07_16380	COG0493	'glutamate synthase
L2Z07_16380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z07_16405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z07_16420	COG0534	Mate efflux family protein
L2Z07_16430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z07_16435	COG4221	oxidoreductase activity
L2Z07_16440	COG0583	DNA-binding transcription factor activity
L2Z07_16455	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z07_16460	COG1530	ribonuclease E activity
L2Z07_16475	COG0546	phosphoglycolate phosphatase activity
L2Z07_16480	COG2378	regulation of single-species biofilm formation
L2Z07_16485	COG0625	glutathione transferase activity
L2Z07_16495	COG0583	DNA-binding transcription factor activity
L2Z07_16550	COG0473	3-isopropylmalate dehydrogenase activity
L2Z07_16605	COG1301	dicarboxylic acid transport
L2Z07_16615	COG1560	Kdo2-lipid A biosynthetic process
L2Z07_16620	COG1280	lysine exporter protein (LysE YggA)
L2Z07_16625	COG0488	(ABC) transporter
L2Z07_16630	COG2900	Belongs to the SlyX family
L2Z07_16640	COG1733	regulation of RNA biosynthetic process
L2Z07_16665	COG0210	DNA helicase
L2Z07_16670	COG0724	RNA recognition motif
L2Z07_16690	COG4651	solute:proton antiporter activity
L2Z07_16690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z07_16715	COG0788	formyltetrahydrofolate deformylase activity
L2Z07_16815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z07_16815	COG2813	Specifically methylates the guanine in position
L2Z07_16825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z07_16835	COG4774	siderophore transport
L2Z07_16845	COG0740	serine-type endopeptidase activity
L2Z07_16865	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z07_16865	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z07_16870	COG0280	phosphate acetyltransferase
L2Z07_16870	COG0857	belongs to the CobB CobQ family
L2Z07_16875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z07_16885	COG0800	Aldolase
L2Z07_16895	COG3265	gluconokinase activity
L2Z07_16900	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_16910	COG2267	carboxylic ester hydrolase activity
L2Z07_16925	COG0793	Belongs to the peptidase S41A family
L2Z07_16960	COG1426	Protein conserved in bacteria
L2Z07_17000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z07_17010	COG1162	GTPase activity
L2Z07_17015	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z07_17030	COG1538	Outer membrane efflux protein
L2Z07_17035	COG0577	efflux transmembrane transporter activity
L2Z07_17035	COG1136	(ABC) transporter
L2Z07_17040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z07_17065	COG0028	Belongs to the TPP enzyme family
L2Z07_17070	COG0440	acetolactate synthase activity
L2Z07_17100	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z07_17115	COG0084	hydrolase, TatD family'
L2Z07_17125	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z07_17135	COG0583	DNA-binding transcription factor activity
L2Z07_17145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z07_17235	COG2205	protein histidine kinase activity
L2Z07_17250	COG2132	Multicopper oxidase
L2Z07_17270	COG2814	Major facilitator Superfamily
L2Z07_17280	COG0697	spore germination
L2Z07_17310	COG3622	Belongs to the hyi family
L2Z07_17315	COG2084	Dehydrogenase
L2Z07_17320	COG1024	Enoyl-CoA hydratase
L2Z07_17325	COG0784	Response regulator, receiver
L2Z07_17325	COG2205	protein histidine kinase activity
L2Z07_17325	COG5002	protein histidine kinase activity
L2Z07_17345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z07_17355	COG3956	TIGRFAM MazG family protein
L2Z07_17360	COG1555	photosystem II stabilization
L2Z07_17365	COG0617	tRNA 3'-terminal CCA addition
L2Z07_17370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z07_17390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z07_17395	COG3028	Belongs to the UPF0307 family
L2Z07_17400	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z07_17415	COG0625	glutathione transferase activity
L2Z07_17420	COG1238	metal cluster binding
L2Z07_17460	COG0072	phenylalanine-tRNA ligase activity
L2Z07_17490	COG0248	Ppx GppA phosphatase
L2Z07_17500	COG0037	tRNA processing
L2Z07_17540	COG1764	response to oxidative stress
L2Z07_17545	COG1846	Transcriptional regulator
L2Z07_17555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z07_17615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z07_17620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z07_17625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z07_17635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z07_17685	COG1214	PFAM Peptidase M22, glycoprotease
L2Z07_17700	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L2Z07_17710	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z07_17715	COG0561	phosphatase activity
L2Z07_17725	COG2132	Multicopper oxidase
L2Z07_17730	COG3667	copper resistance
L2Z07_17745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z07_17750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z07_17755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z07_17785	COG1063	alcohol dehydrogenase
L2Z07_17790	COG0583	DNA-binding transcription factor activity
L2Z07_17795	COG1960	acyl-CoA dehydrogenase activity
L2Z07_17800	COG2814	Major facilitator Superfamily
L2Z07_17805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z07_17815	COG1053	succinate dehydrogenase
L2Z07_17820	COG0583	DNA-binding transcription factor activity
L2Z07_17835	COG0583	DNA-binding transcription factor activity
L2Z07_17865	COG0583	DNA-binding transcription factor activity
L2Z07_17880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z07_17885	COG1309	transcriptional regulator
L2Z07_17905	COG0384	phenazine biosynthesis protein PhzF
L2Z07_17915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z07_17935	COG0745	RESPONSE REGULATOR receiver
L2Z07_17975	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z07_18005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z07_18010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z07_18035	COG0583	DNA-binding transcription factor activity
L2Z07_18055	COG0668	transmembrane transport
L2Z07_18065	COG2081	HI0933 family
L2Z07_18070	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z07_18100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z07_18100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z07_18110	COG0489	protein tyrosine kinase activity
L2Z07_18160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z07_18170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z07_18185	COG0730	response to heat
L2Z07_18195	COG1196	nuclear chromosome segregation
L2Z07_18215	COG2223	nitrite transmembrane transporter activity
L2Z07_18220	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z07_18230	COG0596	Alpha beta hydrolase
L2Z07_18230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z07_18230	COG2226	methyltransferase
L2Z07_18245	COG4106	trans-aconitate 2-methyltransferase activity
L2Z07_18260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z07_18265	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z07_18270	COG0009	L-threonylcarbamoyladenylate synthase
L2Z07_18275	COG3101	peptidyl-lysine hydroxylation
L2Z07_18280	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z07_18305	COG1652	LysM domain
L2Z07_18310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z07_18310	COG0352	thiamine-phosphate diphosphorylase activity
L2Z07_18310	COG0351	phosphomethylpyrimidine kinase
L2Z07_18320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z07_18350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z07_18380	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z07_18395	COG0358	DNA primase activity
L2Z07_18405	COG0564	pseudouridine synthase activity
L2Z07_18430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z07_18450	COG0583	DNA-binding transcription factor activity
L2Z07_18455	COG0473	3-isopropylmalate dehydrogenase activity
L2Z07_18465	COG0657	acetylesterase activity
L2Z07_18475	COG1012	belongs to the aldehyde dehydrogenase family
L2Z07_18495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z07_18495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z07_18510	COG1981	membrane
L2Z07_18555	COG0456	acetyltransferase
L2Z07_18565	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z07_18570	COG0492	ferredoxin-NADP+ reductase activity
L2Z07_18575	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z07_18575	COG1674	ftsk spoiiie
L2Z07_18580	COG1280	lysine exporter protein (LysE YggA)
L2Z07_18595	COG2894	cell division
L2Z07_18610	COG0204	Acyl-transferase
L2Z07_18615	COG2885	chlorophyll binding
L2Z07_18620	COG0210	DNA helicase
L2Z07_18630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z07_18645	COG0121	glutamine amidotransferase
L2Z07_18665	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z07_18670	COG0735	belongs to the Fur family
L2Z07_18695	COG0420	3'-5' exonuclease activity
L2Z07_18715	COG1090	epimerase
L2Z07_18730	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z07_18740	COG2814	Major facilitator Superfamily
L2Z07_18745	COG0405	Gamma-glutamyltransferase
L2Z07_18755	COG0582	viral genome integration into host DNA
L2Z07_18810	COG0629	single-stranded DNA binding
L2Z07_18850	COG0084	hydrolase, TatD family'
L2Z07_18870	COG0477	Major facilitator Superfamily
L2Z07_18875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z07_18885	COG1595	DNA-templated transcription, initiation
L2Z07_18940	COG0531	amino acid
L2Z07_18945	COG2040	homocysteine
L2Z07_18970	COG1309	transcriptional regulator
L2Z07_18975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z07_18980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z07_18990	COG1607	acyl-coa hydrolase
L2Z07_19000	COG0523	cobalamin synthesis protein
L2Z07_19010	COG4681	YaeQ
L2Z07_19020	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z07_19020	COG0726	polysaccharide deacetylase
L2Z07_19025	COG1215	transferase activity, transferring glycosyl groups
L2Z07_19035	COG1024	Enoyl-CoA hydratase
L2Z07_19050	COG1414	Transcriptional regulator
L2Z07_19070	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_19080	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z07_19085	COG2271	Major facilitator Superfamily
L2Z07_19095	COG2267	carboxylic ester hydrolase activity
L2Z07_19100	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_19115	COG0028	Belongs to the TPP enzyme family
L2Z07_19125	COG0477	Major facilitator Superfamily
L2Z07_19130	COG0242	peptide deformylase activity
L2Z07_19135	COG2066	Belongs to the glutaminase family
L2Z07_19140	COG2207	Transcriptional regulator
L2Z07_19145	COG2223	nitrite transmembrane transporter activity
L2Z07_19160	COG0583	DNA-binding transcription factor activity
L2Z07_19165	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z07_19170	COG2271	Major facilitator Superfamily
L2Z07_19175	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z07_19180	COG3958	Transketolase
L2Z07_19190	COG0306	phosphate transporter
L2Z07_19210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z07_19255	COG4181	ATPase activity
L2Z07_19260	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z07_19290	COG0583	DNA-binding transcription factor activity
L2Z07_19300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z07_19305	COG1773	rubredoxin
L2Z07_19355	COG2851	Citrate transporter
L2Z07_19360	COG1253	flavin adenine dinucleotide binding
L2Z07_19400	COG0804	urea catabolic process
L2Z07_19410	COG0830	nickel cation binding
L2Z07_19425	COG0742	ribosomal rna small subunit methyltransferase
L2Z07_19430	COG0768	penicillin binding
L2Z07_19455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z07_19460	COG2878	Part of a membrane complex involved in electron transport
L2Z07_19465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z07_19480	COG3384	dioxygenase
L2Z07_19500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z07_19595	COG0305	Participates in initiation and elongation during chromosome replication