locus-tag	class	description
L2Z12_00090	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z12_00140	COG0339	signal peptide processing
L2Z12_00150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z12_00185	COG0702	epimerase
L2Z12_00190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z12_00210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z12_00240	COG0316	Belongs to the HesB IscA family
L2Z12_00245	COG0822	iron-sulfur transferase activity
L2Z12_00270	COG0776	regulation of translation
L2Z12_00275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z12_00280	COG2207	Transcriptional regulator
L2Z12_00285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z12_00290	COG1960	acyl-CoA dehydrogenase activity
L2Z12_00295	COG1960	acyl-CoA dehydrogenase activity
L2Z12_00310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z12_00330	COG4264	IucA IucC family
L2Z12_00335	COG4264	IucA IucC family
L2Z12_00375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z12_00390	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z12_00410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z12_00415	COG0730	response to heat
L2Z12_00435	COG4773	Receptor
L2Z12_00440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z12_00455	COG1131	(ABC) transporter
L2Z12_00460	COG0842	Transport permease protein
L2Z12_00465	COG0842	Transport permease protein
L2Z12_00520	COG2226	methyltransferase
L2Z12_00545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z12_00550	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
L2Z12_00580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z12_00590	COG0133	tryptophan synthase activity
L2Z12_00605	COG3706	GGDEF domain
L2Z12_00620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z12_00625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z12_00630	COG0022	dehydrogenase e1 component
L2Z12_00635	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z12_00640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z12_00650	COG1063	alcohol dehydrogenase
L2Z12_00655	COG3781	membrane
L2Z12_00665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z12_00665	COG3453	Protein conserved in bacteria
L2Z12_00680	COG0730	response to heat
L2Z12_00700	COG3708	Transcriptional regulator
L2Z12_00700	COG2207	Transcriptional regulator
L2Z12_00705	COG1733	regulation of RNA biosynthetic process
L2Z12_00710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z12_00720	COG2188	Transcriptional regulator
L2Z12_00735	COG4521	taurine ABC transporter
L2Z12_00740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z12_00760	COG0477	Major facilitator Superfamily
L2Z12_00770	COG1027	Aspartate ammonia-lyase
L2Z12_00785	COG0583	DNA-binding transcription factor activity
L2Z12_00790	COG0583	DNA-binding transcription factor activity
L2Z12_00795	COG0183	Belongs to the thiolase family
L2Z12_00800	COG2031	fatty acid transporter
L2Z12_00805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z12_00815	COG0583	DNA-binding transcription factor activity
L2Z12_00825	COG2610	gluconate transmembrane transporter activity
L2Z12_00830	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_00835	COG2207	Transcriptional regulator
L2Z12_00850	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_00875	COG0543	2 iron, 2 sulfur cluster binding
L2Z12_00875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z12_00880	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z12_00885	COG4638	Rieske (2fe-2S)
L2Z12_00895	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z12_00900	COG4149	molybdate abc transporter
L2Z12_00905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z12_00910	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_00915	COG3433	isochorismatase activity
L2Z12_00915	COG1535	isochorismatase
L2Z12_00975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z12_00990	COG0753	catalase activity
L2Z12_01000	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z12_01025	COG3539	Fimbrial protein
L2Z12_01045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z12_01065	COG2072	flavoprotein involved in K transport
L2Z12_01075	COG1538	Outer membrane efflux protein
L2Z12_01080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z12_01085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z12_01105	COG2205	protein histidine kinase activity
L2Z12_01115	COG2207	Transcriptional regulator
L2Z12_01130	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_01185	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z12_01310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z12_01330	COG1120	ATPase activity
L2Z12_01335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z12_01345	COG1064	alcohol dehydrogenase
L2Z12_01360	COG2207	Transcriptional regulator
L2Z12_01365	COG2084	Dehydrogenase
L2Z12_01375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z12_01380	COG0583	DNA-binding transcription factor activity
L2Z12_01390	COG0129	dihydroxy-acid dehydratase activity
L2Z12_01395	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_01410	COG1566	PFAM secretion protein HlyD family protein
L2Z12_01430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z12_01460	COG0583	DNA-binding transcription factor activity
L2Z12_01475	COG2188	Transcriptional regulator
L2Z12_01545	COG1473	amidohydrolase
L2Z12_01555	COG0475	glutathione-regulated potassium exporter activity
L2Z12_01555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z12_01565	COG0583	DNA-binding transcription factor activity
L2Z12_01570	COG1335	isochorismatase
L2Z12_01580	COG1309	transcriptional regulator
L2Z12_01610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z12_01620	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z12_01620	COG1902	pentaerythritol trinitrate reductase activity
L2Z12_01625	COG1846	Transcriptional regulator
L2Z12_01650	COG0753	catalase activity
L2Z12_01665	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_01680	COG3162	membrane
L2Z12_01690	COG3829	transcription factor binding
L2Z12_01695	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_01700	COG1960	acyl-CoA dehydrogenase activity
L2Z12_01720	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_01740	COG2186	Transcriptional regulator
L2Z12_01750	COG0583	DNA-binding transcription factor activity
L2Z12_01755	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z12_01760	COG4829	muconolactone delta-isomerase
L2Z12_01770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z12_01775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z12_01780	COG0183	Belongs to the thiolase family
L2Z12_01785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z12_01795	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_01805	COG3733	amine oxidase
L2Z12_01815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z12_01825	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_01835	COG4638	Rieske (2fe-2S)
L2Z12_01855	COG0154	amidase activity
L2Z12_01865	COG2814	Major facilitator Superfamily
L2Z12_01890	COG1960	acyl-CoA dehydrogenase activity
L2Z12_01895	COG0583	DNA-binding transcription factor activity
L2Z12_01900	COG1414	Transcriptional regulator
L2Z12_01915	COG2391	methyltransferase activity
L2Z12_01925	COG4993	Dehydrogenase
L2Z12_01930	COG3659	wide pore channel activity
L2Z12_01935	COG3420	alginic acid biosynthetic process
L2Z12_01940	COG0710	3-dehydroquinate dehydratase activity
L2Z12_01945	COG3485	protocatechuate 3,4-dioxygenase
L2Z12_01950	COG3485	protocatechuate 3,4-dioxygenase
L2Z12_01955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z12_01960	COG2271	Major facilitator Superfamily
L2Z12_01965	COG0596	Alpha beta hydrolase
L2Z12_01970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z12_01975	COG0183	Belongs to the thiolase family
L2Z12_01980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z12_01985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z12_01995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z12_02000	COG2323	membrane
L2Z12_02045	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z12_02045	COG1902	pentaerythritol trinitrate reductase activity
L2Z12_02070	COG0542	response to heat
L2Z12_02075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z12_02105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z12_02110	COG0569	domain protein
L2Z12_02115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z12_02130	COG4774	siderophore transport
L2Z12_02135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z12_02145	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z12_02165	COG1294	oxidase, subunit
L2Z12_02170	COG4890	Cyd operon protein YbgT
L2Z12_02185	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z12_02195	COG0552	protein localization to endoplasmic reticulum
L2Z12_02220	COG0517	IMP dehydrogenase activity
L2Z12_02220	COG0516	GMP reductase activity
L2Z12_02225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z12_02230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z12_02240	COG0583	DNA-binding transcription factor activity
L2Z12_02245	COG0024	Methionine aminopeptidase
L2Z12_02275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z12_02275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z12_02280	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z12_02285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z12_02285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z12_02285	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z12_02310	COG3300	MHYT domain
L2Z12_02310	COG5001	Diguanylate cyclase
L2Z12_02340	COG2135	peptidase activity
L2Z12_02345	COG0659	secondary active sulfate transmembrane transporter activity
L2Z12_02365	COG1113	amino acid transport
L2Z12_02400	COG1011	Hydrolase
L2Z12_02405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z12_02415	COG2137	regulation of response to DNA damage stimulus
L2Z12_02430	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z12_02465	COG0575	Belongs to the CDS family
L2Z12_02470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z12_02490	COG3852	Histidine kinase
L2Z12_02495	COG2204	response regulator
L2Z12_02550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z12_02555	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z12_02575	COG0697	spore germination
L2Z12_02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z12_02590	COG0303	'Molybdopterin
L2Z12_02595	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z12_02595	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z12_02610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z12_02615	COG0243	molybdopterin cofactor binding
L2Z12_02625	COG0243	molybdopterin cofactor binding
L2Z12_02630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z12_02635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z12_02635	COG2146	nitrite reductase [NAD(P)H] activity
L2Z12_02645	COG0745	RESPONSE REGULATOR receiver
L2Z12_02650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z12_02650	COG1116	anion transmembrane transporter activity
L2Z12_02670	COG0511	ligase activity, forming carbon-carbon bonds
L2Z12_02685	COG2814	Major facilitator Superfamily
L2Z12_02705	COG0069	glutamate synthase activity
L2Z12_02725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z12_02735	COG1454	alcohol dehydrogenase
L2Z12_02740	COG0824	Thioesterase
L2Z12_02750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z12_02765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z12_02770	COG2030	dehydratase
L2Z12_02780	COG0183	Belongs to the thiolase family
L2Z12_02790	COG0583	DNA-binding transcription factor activity
L2Z12_02795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z12_02805	COG1522	sequence-specific DNA binding
L2Z12_02810	COG3135	benzoate transporter
L2Z12_02820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z12_02845	COG0589	response to stress
L2Z12_02850	COG0488	(ABC) transporter
L2Z12_02870	COG4773	Receptor
L2Z12_02900	COG0668	transmembrane transport
L2Z12_02910	COG1309	transcriptional regulator
L2Z12_02930	COG1605	Chorismate mutase
L2Z12_02940	COG4221	oxidoreductase activity
L2Z12_02950	COG0308	aminopeptidase N
L2Z12_02970	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z12_02980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z12_02985	COG1454	alcohol dehydrogenase
L2Z12_03005	COG0531	amino acid
L2Z12_03010	COG4303	Ethanolamine ammonia lyase large subunit
L2Z12_03015	COG4302	ethanolamine ammonia-lyase activity
L2Z12_03020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z12_03020	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z12_03025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z12_03035	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z12_03050	COG0697	spore germination
L2Z12_03055	COG1923	regulation of RNA biosynthetic process
L2Z12_03065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z12_03070	COG0802	atpase or kinase
L2Z12_03090	COG1187	pseudouridine synthase activity
L2Z12_03105	COG0583	DNA-binding transcription factor activity
L2Z12_03120	COG2814	Major facilitator Superfamily
L2Z12_03125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z12_03150	COG0729	surface antigen
L2Z12_03185	COG0745	RESPONSE REGULATOR receiver
L2Z12_03190	COG2205	protein histidine kinase activity
L2Z12_03200	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z12_03205	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z12_03230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z12_03235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z12_03240	COG1960	acyl-CoA dehydrogenase activity
L2Z12_03255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z12_03260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z12_03280	COG0583	DNA-binding transcription factor activity
L2Z12_03295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z12_03305	COG3658	cytochrome
L2Z12_03310	COG1215	transferase activity, transferring glycosyl groups
L2Z12_03315	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z12_03315	COG0726	polysaccharide deacetylase
L2Z12_03340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z12_03345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z12_03355	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z12_03385	COG0305	Participates in initiation and elongation during chromosome replication
L2Z12_03390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z12_03400	COG1305	Transglutaminase-like
L2Z12_03410	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z12_03440	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z12_03445	COG0138	bifunctional purine biosynthesis protein purh
L2Z12_03450	COG0151	Belongs to the GarS family
L2Z12_03455	COG1464	Belongs to the NlpA lipoprotein family
L2Z12_03460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z12_03465	COG2011	ABC-type metal ion transport system permease component
L2Z12_03470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z12_03480	COG1301	dicarboxylic acid transport
L2Z12_03510	COG1794	racemase activity, acting on amino acids and derivatives
L2Z12_03520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z12_03520	COG3008	intermembrane lipid transfer
L2Z12_03525	COG2995	paraquat-inducible protein a
L2Z12_03535	COG2985	domain, Protein
L2Z12_03565	COG0477	Major facilitator Superfamily
L2Z12_03620	COG2186	Transcriptional regulator
L2Z12_03630	COG0786	glutamate:sodium symporter activity
L2Z12_03635	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z12_03660	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z12_03760	COG1610	YqeY-like protein
L2Z12_03765	COG4783	chaperone-mediated protein folding
L2Z12_03790	COG1286	toxin biosynthetic process
L2Z12_03820	COG0778	Nitroreductase
L2Z12_03830	COG0513	Belongs to the DEAD box helicase family
L2Z12_03855	COG2363	Small membrane protein
L2Z12_03885	COG1234	tRNA 3'-trailer cleavage
L2Z12_03890	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z12_03900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z12_03910	COG2819	hydrolase of the alpha beta superfamily
L2Z12_03915	COG1960	acyl-CoA dehydrogenase activity
L2Z12_03920	COG1301	dicarboxylic acid transport
L2Z12_03925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z12_03930	COG3139	Protein of unknown function (DUF1315)
L2Z12_03935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z12_03940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z12_03950	COG0494	nUDIX hydrolase
L2Z12_03960	COG0642	Histidine kinase
L2Z12_03975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z12_03985	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z12_04000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z12_04005	COG0826	peptidase U32
L2Z12_04010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z12_04020	COG4598	ABC transporter
L2Z12_04025	COG4160	amino acid transport
L2Z12_04030	COG4215	(ABC) transporter
L2Z12_04045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z12_04090	COG1131	(ABC) transporter
L2Z12_04095	COG0842	Transport permease protein
L2Z12_04110	COG0772	Belongs to the SEDS family
L2Z12_04115	COG2951	lytic endotransglycosylase activity
L2Z12_04140	COG2207	Transcriptional regulator
L2Z12_04155	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z12_04160	COG0024	Methionine aminopeptidase
L2Z12_04170	COG2223	nitrite transmembrane transporter activity
L2Z12_04180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z12_04185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z12_04190	COG1960	acyl-CoA dehydrogenase activity
L2Z12_04205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z12_04210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z12_04215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z12_04235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z12_04245	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z12_04250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z12_04285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z12_04295	COG0174	glutamine synthetase
L2Z12_04310	COG0582	viral genome integration into host DNA
L2Z12_04405	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z12_04510	COG5410	chromosome segregation
L2Z12_04685	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z12_04720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z12_04730	COG0302	gtp cyclohydrolase
L2Z12_04760	COG3739	integral membrane protein
L2Z12_04775	COG1169	isochorismate synthase
L2Z12_04785	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z12_04790	COG1132	(ABC) transporter
L2Z12_04795	COG1132	(ABC) transporter
L2Z12_04805	COG1535	isochorismatase
L2Z12_04805	COG3433	isochorismatase activity
L2Z12_04810	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z12_04815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z12_04825	COG4774	siderophore transport
L2Z12_04830	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z12_04835	COG4604	ABC transporter, ATP-binding protein
L2Z12_04840	COG4605	iron ion homeostasis
L2Z12_04845	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z12_04850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z12_04865	COG2964	Protein conserved in bacteria
L2Z12_04875	COG1741	Belongs to the pirin family
L2Z12_04895	COG1309	transcriptional regulator
L2Z12_04905	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z12_04910	COG2814	Major facilitator Superfamily
L2Z12_04945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z12_04945	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z12_04950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z12_04960	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_04970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z12_04975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z12_04980	COG0583	DNA-binding transcription factor activity
L2Z12_04985	COG1113	amino acid transport
L2Z12_05035	COG2508	Transcriptional regulator
L2Z12_05035	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z12_05070	COG2879	small protein
L2Z12_05075	COG1966	Carbon starvation protein
L2Z12_05120	COG1067	ATP-dependent peptidase activity
L2Z12_05125	COG0583	DNA-binding transcription factor activity
L2Z12_05150	COG1686	Belongs to the peptidase S11 family
L2Z12_05155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z12_05190	COG0616	signal peptide processing
L2Z12_05195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z12_05205	COG0573	inorganic phosphate transmembrane transporter activity
L2Z12_05210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z12_05215	COG1113	amino acid transport
L2Z12_05220	COG3961	Belongs to the TPP enzyme family
L2Z12_05225	COG1522	sequence-specific DNA binding
L2Z12_05235	COG0076	glutamate decarboxylase activity
L2Z12_05240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z12_05250	COG1309	transcriptional regulator
L2Z12_05265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z12_05300	COG0352	thiamine-phosphate diphosphorylase activity
L2Z12_05325	COG0612	Peptidase, M16
L2Z12_05335	COG1823	symporter activity
L2Z12_05340	COG0583	DNA-binding transcription factor activity
L2Z12_05345	COG0477	Major facilitator Superfamily
L2Z12_05365	COG1187	pseudouridine synthase activity
L2Z12_05380	COG1686	Belongs to the peptidase S11 family
L2Z12_05385	COG1252	NADH dehydrogenase
L2Z12_05395	COG0415	Belongs to the DNA photolyase family
L2Z12_05410	COG1215	transferase activity, transferring glycosyl groups
L2Z12_05440	COG2070	2-Nitropropane dioxygenase
L2Z12_05495	COG0556	nucleotide-excision repair
L2Z12_05515	COG0436	Aminotransferase
L2Z12_05545	COG4221	oxidoreductase activity
L2Z12_05555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z12_05560	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z12_05570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z12_05585	COG0681	Belongs to the peptidase S26 family
L2Z12_05600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z12_05620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z12_05625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z12_05630	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z12_05640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z12_05645	COG4208	sulfate ABC transporter
L2Z12_05650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z12_05655	COG0583	DNA-binding transcription factor activity
L2Z12_05660	COG4625	pathogenesis
L2Z12_05675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z12_05690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z12_05700	COG1051	belongs to the nudix hydrolase family
L2Z12_05700	COG1056	cytidyltransferase-related domain
L2Z12_05705	COG1024	Enoyl-CoA hydratase
L2Z12_05715	COG2814	Major facilitator Superfamily
L2Z12_05720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z12_05720	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z12_05740	COG1473	amidohydrolase
L2Z12_05745	COG0824	Thioesterase
L2Z12_05765	COG0823	Involved in the tonB-independent uptake of proteins
L2Z12_05785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z12_05820	COG0628	permease
L2Z12_05830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z12_05835	COG0596	Alpha beta hydrolase
L2Z12_05840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z12_05840	COG0616	signal peptide processing
L2Z12_05850	COG2333	competence protein COMEC
L2Z12_05850	COG0658	competence protein
L2Z12_05855	COG1136	(ABC) transporter
L2Z12_05860	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z12_05890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z12_05940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z12_05945	COG1280	lysine exporter protein (LysE YggA)
L2Z12_05960	COG0019	diaminopimelate decarboxylase activity
L2Z12_05970	COG1113	amino acid transport
L2Z12_05985	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z12_05995	COG3339	Conserved Protein
L2Z12_06000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z12_06005	COG0243	molybdopterin cofactor binding
L2Z12_06010	COG1929	Belongs to the glycerate kinase type-1 family
L2Z12_06025	COG0778	Nitroreductase
L2Z12_06060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z12_06075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z12_06095	COG0741	lytic transglycosylase activity
L2Z12_06115	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z12_06120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z12_06145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z12_06150	COG1597	lipid kinase activity
L2Z12_06165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z12_06170	COG0477	Major facilitator Superfamily
L2Z12_06220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z12_06225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z12_06250	COG0505	Belongs to the CarA family
L2Z12_06270	COG0589	response to stress
L2Z12_06305	COG2321	neutral zinc metallopeptidase
L2Z12_06310	COG2354	Protein conserved in bacteria
L2Z12_06330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z12_06355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z12_06360	COG1053	succinate dehydrogenase
L2Z12_06365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z12_06370	COG2009	succinate dehydrogenase
L2Z12_06410	COG2921	Belongs to the UPF0250 family
L2Z12_06415	COG0321	lipoyl(octanoyl) transferase activity
L2Z12_06430	COG0531	amino acid
L2Z12_06440	COG1733	regulation of RNA biosynthetic process
L2Z12_06445	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z12_06450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z12_06450	COG1648	precorrin-2 dehydrogenase activity
L2Z12_06465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z12_06495	COG0671	phosphoesterase, PA-phosphatase related
L2Z12_06500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z12_06510	COG1538	Outer membrane efflux protein
L2Z12_06515	COG0393	Putative heavy-metal-binding
L2Z12_06520	COG0393	Putative heavy-metal-binding
L2Z12_06530	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_06540	COG0525	valine-tRNA ligase activity
L2Z12_06560	COG0583	DNA-binding transcription factor activity
L2Z12_06565	COG0004	ammonium transporteR
L2Z12_06575	COG0642	Histidine kinase
L2Z12_06580	COG0745	RESPONSE REGULATOR receiver
L2Z12_06625	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z12_06640	COG2315	Protein conserved in bacteria
L2Z12_06645	COG0142	geranyltranstransferase activity
L2Z12_06650	COG2828	Protein conserved in bacteria
L2Z12_06655	COG1113	amino acid transport
L2Z12_06675	COG2207	Transcriptional regulator
L2Z12_06700	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z12_06710	COG0560	Phosphoserine phosphatase
L2Z12_06720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z12_06730	COG1530	ribonuclease E activity
L2Z12_06735	COG0424	maF-like protein
L2Z12_06740	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z12_06745	COG1792	Involved in formation and maintenance of cell shape
L2Z12_06750	COG1077	Cell shape determining protein MreB Mrl
L2Z12_06755	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z12_06765	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z12_06790	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z12_06795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z12_06800	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z12_06805	COG1115	amino acid carrier protein
L2Z12_06825	COG2814	Major facilitator Superfamily
L2Z12_06830	COG1289	transmembrane transporter activity
L2Z12_06840	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z12_06880	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z12_06885	COG2832	Protein of unknown function (DUF454)
L2Z12_06895	COG5510	response to toxic substance
L2Z12_06925	COG0840	transmembrane signaling receptor activity
L2Z12_06965	COG3422	double-strand break repair
L2Z12_06970	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z12_06975	COG3189	MarR family transcriptional regulator
L2Z12_06985	COG0354	folic acid binding
L2Z12_06990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z12_07000	COG0679	Auxin Efflux Carrier
L2Z12_07005	COG1902	pentaerythritol trinitrate reductase activity
L2Z12_07010	COG4772	TonB-dependent receptor
L2Z12_07015	COG2094	Belongs to the DNA glycosylase MPG family
L2Z12_07040	COG1217	gtp-binding protein TYPA
L2Z12_07045	COG2233	PERMEase
L2Z12_07055	COG0833	amino acid
L2Z12_07060	COG1690	Belongs to the RtcB family
L2Z12_07070	COG2885	chlorophyll binding
L2Z12_07070	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z12_07080	COG0183	Belongs to the thiolase family
L2Z12_07100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z12_07120	COG2207	Transcriptional regulator
L2Z12_07125	COG0183	Belongs to the thiolase family
L2Z12_07145	COG2153	protein acetylation
L2Z12_07155	COG1272	protein, Hemolysin III
L2Z12_07160	COG0477	Major facilitator Superfamily
L2Z12_07175	COG0450	alkyl hydroperoxide reductase
L2Z12_07195	COG0285	dihydrofolate synthase activity
L2Z12_07245	COG2096	Adenosyltransferase
L2Z12_07265	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z12_07270	COG0745	RESPONSE REGULATOR receiver
L2Z12_07275	COG2205	protein histidine kinase activity
L2Z12_07285	COG1960	acyl-CoA dehydrogenase activity
L2Z12_07290	COG1960	acyl-CoA dehydrogenase activity
L2Z12_07355	COG0438	transferase activity, transferring glycosyl groups
L2Z12_07360	COG0463	Glycosyl transferase, family 2
L2Z12_07365	COG0726	polysaccharide deacetylase
L2Z12_07385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z12_07390	COG2205	protein histidine kinase activity
L2Z12_07395	COG4695	Portal protein
L2Z12_07530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L2Z12_07540	COG3646	Phage regulatory protein
L2Z12_07585	COG0629	single-stranded DNA binding
L2Z12_07590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z12_07635	COG1862	Preprotein translocase
L2Z12_07650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z12_07660	COG3781	membrane
L2Z12_07665	COG0613	PHP domain protein
L2Z12_07675	COG2350	Protein conserved in bacteria
L2Z12_07705	COG1607	acyl-coa hydrolase
L2Z12_07765	COG2199	diguanylate cyclase activity
L2Z12_07775	COG1408	metallophosphoesterase
L2Z12_07780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z12_07790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z12_07810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z12_07815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z12_07830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z12_07840	COG2969	positive regulation of protein catabolic process
L2Z12_07860	COG1960	acyl-CoA dehydrogenase activity
L2Z12_07865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z12_07880	COG1309	transcriptional regulator
L2Z12_07885	COG1960	acyl-CoA dehydrogenase activity
L2Z12_07930	COG1183	phosphatidylcholine synthase activity
L2Z12_07935	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z12_07965	COG0739	heme binding
L2Z12_07965	COG0741	lytic transglycosylase activity
L2Z12_07965	COG1196	nuclear chromosome segregation
L2Z12_07975	COG1702	phosphate starvation-inducible protein PhoH
L2Z12_08010	COG1295	ribonuclease BN
L2Z12_08020	COG2169	Transcriptional regulator
L2Z12_08025	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z12_08070	COG0557	exoribonuclease II activity
L2Z12_08075	COG0339	signal peptide processing
L2Z12_08080	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z12_08110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z12_08115	COG1960	acyl-CoA dehydrogenase activity
L2Z12_08270	COG0626	cystathionine gamma-synthase activity
L2Z12_08275	COG0433	COG0433 Predicted ATPase
L2Z12_08280	COG1017	nitric oxide dioxygenase activity
L2Z12_08280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z12_08285	COG1959	2 iron, 2 sulfur cluster binding
L2Z12_08300	COG1301	dicarboxylic acid transport
L2Z12_08305	COG1946	Acyl-CoA thioesterase
L2Z12_08325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z12_08330	COG1040	competence protein
L2Z12_08335	COG0494	nUDIX hydrolase
L2Z12_08345	COG0598	Magnesium transport protein CorA
L2Z12_08355	COG2854	intermembrane phospholipid transfer
L2Z12_08365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z12_08370	COG1127	ABC transporter
L2Z12_08380	COG0513	Belongs to the DEAD box helicase family
L2Z12_08400	COG0408	coproporphyrinogen oxidase activity
L2Z12_08415	COG1960	acyl-CoA dehydrogenase activity
L2Z12_08425	COG1983	PspC domain protein
L2Z12_08430	COG0517	IMP dehydrogenase activity
L2Z12_08460	COG3293	Transposase
L2Z12_08485	COG0583	DNA-binding transcription factor activity
L2Z12_08525	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_08535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z12_08540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z12_08545	COG0833	amino acid
L2Z12_08580	COG1192	Involved in chromosome partitioning
L2Z12_08585	COG0628	permease
L2Z12_08595	COG1289	transmembrane transporter activity
L2Z12_08610	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z12_08615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z12_08625	COG0277	FAD linked oxidase domain protein
L2Z12_08630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z12_08655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z12_08660	COG5380	lipid catabolic process
L2Z12_08680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z12_08730	COG0194	GDP metabolic process
L2Z12_08745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z12_08765	COG3307	-O-antigen
L2Z12_08780	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z12_08785	COG1704	LemA family
L2Z12_08795	COG0493	'glutamate synthase
L2Z12_08800	COG0067	glutamate synthase
L2Z12_08800	COG0069	glutamate synthase activity
L2Z12_08800	COG0070	glutamate synthase
L2Z12_08850	COG2226	methyltransferase
L2Z12_08865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z12_08870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z12_08915	COG0833	amino acid
L2Z12_08980	COG0488	(ABC) transporter
L2Z12_08985	COG2873	o-acetylhomoserine
L2Z12_08990	COG4221	oxidoreductase activity
L2Z12_08995	COG0659	secondary active sulfate transmembrane transporter activity
L2Z12_09020	COG0427	acetyl-CoA hydrolase
L2Z12_09050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z12_09090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z12_09150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2Z12_09165	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z12_09170	COG1733	regulation of RNA biosynthetic process
L2Z12_09185	COG1733	regulation of RNA biosynthetic process
L2Z12_09205	COG0667	Aldo Keto reductase
L2Z12_09225	COG0583	DNA-binding transcription factor activity
L2Z12_09230	COG2814	Major facilitator Superfamily
L2Z12_09260	COG1335	isochorismatase
L2Z12_09270	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_09275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z12_09285	COG1113	amino acid transport
L2Z12_09295	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z12_09310	COG2814	Major facilitator Superfamily
L2Z12_09320	COG0351	phosphomethylpyrimidine kinase
L2Z12_09320	COG0352	thiamine-phosphate diphosphorylase activity
L2Z12_09320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z12_09340	COG1309	transcriptional regulator
L2Z12_09345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z12_09360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z12_09370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z12_09375	COG3162	membrane
L2Z12_09380	COG0784	Response regulator, receiver
L2Z12_09380	COG2198	Histidine kinase
L2Z12_09380	COG2205	protein histidine kinase activity
L2Z12_09405	COG1522	sequence-specific DNA binding
L2Z12_09410	COG1335	isochorismatase
L2Z12_09415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z12_09425	COG0668	transmembrane transport
L2Z12_09430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z12_09435	COG1519	Transferase
L2Z12_09440	COG1902	pentaerythritol trinitrate reductase activity
L2Z12_09460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z12_09485	COG0426	domain, Protein
L2Z12_09485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z12_09490	COG4774	siderophore transport
L2Z12_09495	COG2119	membrane
L2Z12_09505	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z12_09515	COG4942	peptidase
L2Z12_09530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z12_09540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z12_09560	COG0189	ligase activity
L2Z12_09580	COG0708	Exodeoxyribonuclease III
L2Z12_09585	COG1393	Belongs to the ArsC family
L2Z12_09600	COG3706	GGDEF domain
L2Z12_09635	COG2351	hydroxyisourate hydrolase activity
L2Z12_09640	COG2233	PERMEase
L2Z12_09650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z12_09660	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z12_09670	COG3150	esterase
L2Z12_09735	COG2918	glutathione biosynthetic process
L2Z12_09750	COG2733	membrane
L2Z12_09755	COG0436	Aminotransferase
L2Z12_09760	COG0534	Mate efflux family protein
L2Z12_09845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z12_09850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z12_09860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z12_09870	COG2205	protein histidine kinase activity
L2Z12_09880	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z12_09895	COG0010	Belongs to the arginase family
L2Z12_09925	COG2188	Transcriptional regulator
L2Z12_09935	COG0523	cobalamin synthesis protein
L2Z12_09945	COG1113	amino acid transport
L2Z12_09955	COG0625	glutathione transferase activity
L2Z12_09975	COG1683	Conserved Protein
L2Z12_09980	COG0534	Mate efflux family protein
L2Z12_09985	COG0385	Bile acid
L2Z12_09990	COG1335	isochorismatase
L2Z12_09995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z12_10015	COG2116	formate transmembrane transporter activity
L2Z12_10020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z12_10025	COG2133	pyrroloquinoline quinone binding
L2Z12_10030	COG2983	Belongs to the UPF0260 family
L2Z12_10050	COG1194	a g-specific adenine glycosylase
L2Z12_10065	COG2818	Glycosylase
L2Z12_10070	COG1064	alcohol dehydrogenase
L2Z12_10100	COG0583	DNA-binding transcription factor activity
L2Z12_10105	COG0656	L-ascorbic acid biosynthetic process
L2Z12_10110	COG2814	Major facilitator Superfamily
L2Z12_10145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z12_10160	COG2233	PERMEase
L2Z12_10165	COG0583	DNA-binding transcription factor activity
L2Z12_10200	COG0733	neurotransmitter:sodium symporter activity
L2Z12_10240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z12_10245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z12_10250	COG0596	Alpha beta hydrolase
L2Z12_10275	COG0488	(ABC) transporter
L2Z12_10280	COG4372	Transposase
L2Z12_10295	COG0586	Pfam SNARE associated Golgi protein
L2Z12_10305	COG0187	DNA topoisomerase II activity
L2Z12_10315	COG0592	DNA-directed DNA polymerase activity
L2Z12_10340	COG0706	membrane insertase activity
L2Z12_10355	COG1230	cation diffusion facilitator family transporter
L2Z12_10360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z12_10375	COG0402	S-adenosylhomocysteine deaminase activity
L2Z12_10385	COG0754	glutathionylspermidine amidase activity
L2Z12_10395	COG0861	Integral membrane protein TerC family
L2Z12_10410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z12_10425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z12_10430	COG2951	lytic endotransglycosylase activity
L2Z12_10460	COG0583	DNA-binding transcription factor activity
L2Z12_10480	COG0657	acetylesterase activity
L2Z12_10485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z12_10525	COG1047	Peptidyl-prolyl cis-trans
L2Z12_10535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z12_10540	COG0196	riboflavin kinase activity
L2Z12_10550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z12_10555	COG1309	transcriptional regulator
L2Z12_10560	COG1116	anion transmembrane transporter activity
L2Z12_10565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z12_10570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z12_10575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z12_10580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z12_10600	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_10605	COG0546	phosphoglycolate phosphatase activity
L2Z12_10660	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z12_10665	COG0728	peptidoglycan biosynthetic process
L2Z12_10705	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z12_10710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z12_10715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z12_10755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z12_10760	COG0110	maltose O-acetyltransferase activity
L2Z12_10770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z12_10785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z12_10790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z12_10800	COG2186	Transcriptional regulator
L2Z12_10810	COG0277	FAD linked oxidase domain protein
L2Z12_10815	COG1448	Aminotransferase
L2Z12_10820	COG1802	Transcriptional regulator
L2Z12_10835	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z12_10890	COG0564	pseudouridine synthase activity
L2Z12_10930	COG0251	oxidation-reduction process
L2Z12_10935	COG1113	amino acid transport
L2Z12_10940	COG1113	amino acid transport
L2Z12_10960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z12_10965	COG1960	acyl-CoA dehydrogenase activity
L2Z12_10970	COG1024	Enoyl-CoA hydratase
L2Z12_10975	COG1024	Enoyl-CoA hydratase
L2Z12_10980	COG0477	Major facilitator Superfamily
L2Z12_10985	COG3916	Acyl-homoserine-lactone synthase
L2Z12_10995	COG2197	response regulator
L2Z12_11005	COG1960	acyl-CoA dehydrogenase activity
L2Z12_11010	COG3321	synthase
L2Z12_11010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z12_11010	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z12_11010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z12_11030	COG2267	carboxylic ester hydrolase activity
L2Z12_11050	COG0271	Belongs to the BolA IbaG family
L2Z12_11060	COG1192	Involved in chromosome partitioning
L2Z12_11075	COG0586	Pfam SNARE associated Golgi protein
L2Z12_11080	COG2259	Doxx family
L2Z12_11085	COG4399	Belongs to the UPF0754 family
L2Z12_11090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z12_11090	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z12_11135	COG0281	malic enzyme
L2Z12_11140	COG2837	iron assimilation
L2Z12_11145	COG1280	lysine exporter protein (LysE YggA)
L2Z12_11150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z12_11155	COG1121	(ABC) transporter
L2Z12_11220	COG0386	Belongs to the glutathione peroxidase family
L2Z12_11235	COG1309	transcriptional regulator
L2Z12_11240	COG0697	spore germination
L2Z12_11250	COG0758	DNA mediated transformation
L2Z12_11320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z12_11330	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z12_11370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z12_11380	COG0477	Major facilitator Superfamily
L2Z12_11390	COG1253	flavin adenine dinucleotide binding
L2Z12_11395	COG3012	SEC-C Motif Domain Protein
L2Z12_11400	COG2860	membrane
L2Z12_11405	COG0477	Major facilitator Superfamily
L2Z12_11415	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z12_11430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z12_11440	COG3293	Transposase
L2Z12_11455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z12_11525	COG0659	secondary active sulfate transmembrane transporter activity
L2Z12_11550	COG0789	Transcriptional regulator
L2Z12_11635	COG0347	Belongs to the P(II) protein family
L2Z12_11665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z12_11665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z12_11705	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z12_11710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z12_11715	COG0793	Belongs to the peptidase S41A family
L2Z12_11730	COG2197	response regulator
L2Z12_11740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z12_11750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z12_11755	COG4974	Belongs to the 'phage' integrase family
L2Z12_11780	COG0772	Belongs to the SEDS family
L2Z12_11785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z12_11790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z12_11795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z12_11820	COG0697	spore germination
L2Z12_11825	COG1538	Outer membrane efflux protein
L2Z12_11845	COG3275	phosphorelay sensor kinase activity
L2Z12_11855	COG0181	hydroxymethylbilane synthase activity
L2Z12_11900	COG1716	ATPase activity
L2Z12_11905	COG0546	phosphoglycolate phosphatase activity
L2Z12_12005	COG2056	Na+-H+ antiporter family
L2Z12_12030	COG0326	Molecular chaperone. Has ATPase activity
L2Z12_12045	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z12_12105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z12_12110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z12_12110	COG2169	Transcriptional regulator
L2Z12_12140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z12_12150	COG0497	DNA recombination
L2Z12_12165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z12_12175	COG0237	dephospho-CoA kinase activity
L2Z12_12230	COG0195	Participates in both transcription termination and antitermination
L2Z12_12245	COG1320	monovalent cation:proton antiporter activity
L2Z12_12250	COG2212	antiporter activity
L2Z12_12255	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z12_12260	COG0651	ATP synthesis coupled electron transport
L2Z12_12265	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z12_12270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z12_12270	COG2111	Na H antiporter
L2Z12_12285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z12_12290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z12_12305	COG2226	methyltransferase
L2Z12_12325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z12_12330	COG1074	ATP-dependent DNA helicase activity
L2Z12_12335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z12_12340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z12_12355	COG0598	Magnesium transport protein CorA
L2Z12_12360	COG0789	Transcriptional regulator
L2Z12_12365	COG0484	heat shock protein binding
L2Z12_12380	COG0475	glutathione-regulated potassium exporter activity
L2Z12_12380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z12_12385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z12_12405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z12_12415	COG4535	Mg2 and Co2 transporter CorC
L2Z12_12420	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z12_12430	COG0644	oxidoreductase
L2Z12_12430	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z12_12440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z12_12455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z12_12460	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z12_12470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z12_12470	COG0493	'glutamate synthase
L2Z12_12495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z12_12510	COG0534	Mate efflux family protein
L2Z12_12520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z12_12525	COG4221	oxidoreductase activity
L2Z12_12530	COG0583	DNA-binding transcription factor activity
L2Z12_12545	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z12_12550	COG1530	ribonuclease E activity
L2Z12_12565	COG0546	phosphoglycolate phosphatase activity
L2Z12_12570	COG2378	regulation of single-species biofilm formation
L2Z12_12575	COG0625	glutathione transferase activity
L2Z12_12585	COG0583	DNA-binding transcription factor activity
L2Z12_12640	COG0473	3-isopropylmalate dehydrogenase activity
L2Z12_12695	COG1301	dicarboxylic acid transport
L2Z12_12705	COG1560	Kdo2-lipid A biosynthetic process
L2Z12_12710	COG1280	lysine exporter protein (LysE YggA)
L2Z12_12715	COG0488	(ABC) transporter
L2Z12_12720	COG2900	Belongs to the SlyX family
L2Z12_12730	COG1733	regulation of RNA biosynthetic process
L2Z12_12755	COG0210	DNA helicase
L2Z12_12760	COG0724	RNA recognition motif
L2Z12_12780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z12_12780	COG4651	solute:proton antiporter activity
L2Z12_12805	COG0788	formyltetrahydrofolate deformylase activity
L2Z12_12905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z12_12905	COG2813	Specifically methylates the guanine in position
L2Z12_12915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z12_12945	COG0740	serine-type endopeptidase activity
L2Z12_12965	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z12_12965	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z12_12970	COG0857	belongs to the CobB CobQ family
L2Z12_12970	COG0280	phosphate acetyltransferase
L2Z12_12975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z12_12985	COG0800	Aldolase
L2Z12_12995	COG3265	gluconokinase activity
L2Z12_13000	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_13010	COG2267	carboxylic ester hydrolase activity
L2Z12_13025	COG0793	Belongs to the peptidase S41A family
L2Z12_13060	COG1426	Protein conserved in bacteria
L2Z12_13100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z12_13110	COG1162	GTPase activity
L2Z12_13115	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z12_13130	COG1538	Outer membrane efflux protein
L2Z12_13135	COG0577	efflux transmembrane transporter activity
L2Z12_13135	COG1136	(ABC) transporter
L2Z12_13140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z12_13165	COG0028	Belongs to the TPP enzyme family
L2Z12_13170	COG0440	acetolactate synthase activity
L2Z12_13200	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z12_13215	COG0084	hydrolase, TatD family'
L2Z12_13225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z12_13235	COG0583	DNA-binding transcription factor activity
L2Z12_13245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z12_13250	COG2814	Major facilitator Superfamily
L2Z12_13260	COG0697	spore germination
L2Z12_13290	COG3622	Belongs to the hyi family
L2Z12_13295	COG2084	Dehydrogenase
L2Z12_13300	COG1024	Enoyl-CoA hydratase
L2Z12_13305	COG2205	protein histidine kinase activity
L2Z12_13305	COG5002	protein histidine kinase activity
L2Z12_13305	COG0784	Response regulator, receiver
L2Z12_13325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z12_13335	COG3956	TIGRFAM MazG family protein
L2Z12_13340	COG1555	photosystem II stabilization
L2Z12_13345	COG0617	tRNA 3'-terminal CCA addition
L2Z12_13350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z12_13370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z12_13375	COG3028	Belongs to the UPF0307 family
L2Z12_13380	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z12_13395	COG0625	glutathione transferase activity
L2Z12_13400	COG1238	metal cluster binding
L2Z12_13445	COG0072	phenylalanine-tRNA ligase activity
L2Z12_13475	COG0248	Ppx GppA phosphatase
L2Z12_13485	COG0037	tRNA processing
L2Z12_13525	COG1764	response to oxidative stress
L2Z12_13530	COG1846	Transcriptional regulator
L2Z12_13540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z12_13600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z12_13605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z12_13610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z12_13670	COG1214	PFAM Peptidase M22, glycoprotease
L2Z12_13685	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L2Z12_13695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z12_13700	COG0561	phosphatase activity
L2Z12_13710	COG2132	Multicopper oxidase
L2Z12_13715	COG3667	copper resistance
L2Z12_13730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z12_13735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z12_13740	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z12_13770	COG1063	alcohol dehydrogenase
L2Z12_13775	COG0583	DNA-binding transcription factor activity
L2Z12_13780	COG1960	acyl-CoA dehydrogenase activity
L2Z12_13785	COG2814	Major facilitator Superfamily
L2Z12_13790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z12_13800	COG1053	succinate dehydrogenase
L2Z12_13805	COG0583	DNA-binding transcription factor activity
L2Z12_13825	COG0583	DNA-binding transcription factor activity
L2Z12_13855	COG0583	DNA-binding transcription factor activity
L2Z12_13870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z12_13875	COG1309	transcriptional regulator
L2Z12_13905	COG0384	phenazine biosynthesis protein PhzF
L2Z12_13915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z12_13935	COG0745	RESPONSE REGULATOR receiver
L2Z12_13975	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z12_14005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z12_14010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z12_14035	COG0583	DNA-binding transcription factor activity
L2Z12_14055	COG0668	transmembrane transport
L2Z12_14065	COG2081	HI0933 family
L2Z12_14070	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z12_14100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z12_14100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z12_14110	COG0489	protein tyrosine kinase activity
L2Z12_14160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z12_14170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z12_14185	COG0730	response to heat
L2Z12_14195	COG1196	nuclear chromosome segregation
L2Z12_14215	COG2223	nitrite transmembrane transporter activity
L2Z12_14220	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z12_14230	COG0596	Alpha beta hydrolase
L2Z12_14230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z12_14230	COG2226	methyltransferase
L2Z12_14245	COG4106	trans-aconitate 2-methyltransferase activity
L2Z12_14260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z12_14265	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z12_14270	COG0009	L-threonylcarbamoyladenylate synthase
L2Z12_14275	COG3101	peptidyl-lysine hydroxylation
L2Z12_14280	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z12_14305	COG1652	LysM domain
L2Z12_14310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z12_14310	COG0352	thiamine-phosphate diphosphorylase activity
L2Z12_14310	COG0351	phosphomethylpyrimidine kinase
L2Z12_14320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z12_14350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z12_14380	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z12_14395	COG0358	DNA primase activity
L2Z12_14405	COG0564	pseudouridine synthase activity
L2Z12_14430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z12_14450	COG0583	DNA-binding transcription factor activity
L2Z12_14455	COG0473	3-isopropylmalate dehydrogenase activity
L2Z12_14465	COG0657	acetylesterase activity
L2Z12_14475	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_14495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z12_14495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z12_14510	COG1981	membrane
L2Z12_14555	COG0456	acetyltransferase
L2Z12_14565	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z12_14570	COG0492	ferredoxin-NADP+ reductase activity
L2Z12_14575	COG1674	ftsk spoiiie
L2Z12_14575	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z12_14580	COG1280	lysine exporter protein (LysE YggA)
L2Z12_14595	COG2894	cell division
L2Z12_14610	COG0204	Acyl-transferase
L2Z12_14615	COG2885	chlorophyll binding
L2Z12_14620	COG0210	DNA helicase
L2Z12_14630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z12_14645	COG0121	glutamine amidotransferase
L2Z12_14665	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z12_14670	COG0735	belongs to the Fur family
L2Z12_14695	COG0420	3'-5' exonuclease activity
L2Z12_14715	COG1090	epimerase
L2Z12_14730	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z12_14740	COG2814	Major facilitator Superfamily
L2Z12_14745	COG0405	Gamma-glutamyltransferase
L2Z12_14820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z12_14915	COG1484	DNA-dependent DNA replication
L2Z12_15120	COG2026	Addiction module toxin, RelE StbE family
L2Z12_15160	COG0592	DNA-directed DNA polymerase activity
L2Z12_15270	COG0582	viral genome integration into host DNA
L2Z12_15325	COG0629	single-stranded DNA binding
L2Z12_15345	COG4372	Transposase
L2Z12_15390	COG0084	hydrolase, TatD family'
L2Z12_15410	COG0477	Major facilitator Superfamily
L2Z12_15415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z12_15425	COG1595	DNA-templated transcription, initiation
L2Z12_15480	COG0531	amino acid
L2Z12_15485	COG2040	homocysteine
L2Z12_15510	COG1309	transcriptional regulator
L2Z12_15515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z12_15520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z12_15530	COG1607	acyl-coa hydrolase
L2Z12_15540	COG0523	cobalamin synthesis protein
L2Z12_15550	COG4681	YaeQ
L2Z12_15560	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z12_15560	COG0726	polysaccharide deacetylase
L2Z12_15565	COG1215	transferase activity, transferring glycosyl groups
L2Z12_15575	COG1024	Enoyl-CoA hydratase
L2Z12_15590	COG1414	Transcriptional regulator
L2Z12_15610	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_15620	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z12_15625	COG2271	Major facilitator Superfamily
L2Z12_15635	COG2267	carboxylic ester hydrolase activity
L2Z12_15640	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_15655	COG0028	Belongs to the TPP enzyme family
L2Z12_15665	COG0477	Major facilitator Superfamily
L2Z12_15670	COG0242	peptide deformylase activity
L2Z12_15675	COG2066	Belongs to the glutaminase family
L2Z12_15680	COG2207	Transcriptional regulator
L2Z12_15685	COG2223	nitrite transmembrane transporter activity
L2Z12_15700	COG0583	DNA-binding transcription factor activity
L2Z12_15705	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_15710	COG2271	Major facilitator Superfamily
L2Z12_15715	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z12_15720	COG3958	Transketolase
L2Z12_15730	COG0306	phosphate transporter
L2Z12_15750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z12_15795	COG4181	ATPase activity
L2Z12_15800	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z12_15825	COG0583	DNA-binding transcription factor activity
L2Z12_15835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z12_15840	COG1773	rubredoxin
L2Z12_15890	COG2851	Citrate transporter
L2Z12_15895	COG1253	flavin adenine dinucleotide binding
L2Z12_15935	COG0804	urea catabolic process
L2Z12_15945	COG0830	nickel cation binding
L2Z12_15960	COG0742	ribosomal rna small subunit methyltransferase
L2Z12_15965	COG0768	penicillin binding
L2Z12_15990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z12_15995	COG2878	Part of a membrane complex involved in electron transport
L2Z12_16000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z12_16010	COG3384	dioxygenase
L2Z12_16360	COG0739	heme binding
L2Z12_16460	COG0006	proline dipeptidase activity
L2Z12_16465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z12_16470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z12_16490	COG1279	arginine transmembrane transporter activity
L2Z12_16495	COG0583	DNA-binding transcription factor activity
L2Z12_16535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z12_16540	COG0741	lytic transglycosylase activity
L2Z12_16540	COG1388	LysM domain
L2Z12_16540	COG0741	lytic transglycosylase activity
L2Z12_16540	COG1388	LysM domain
L2Z12_16550	COG4174	ABC transporter (Permease)
L2Z12_16555	COG4239	(ABC) transporter, permease
L2Z12_16560	COG4172	Belongs to the ABC transporter superfamily
L2Z12_16580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z12_16590	COG2203	Gaf domain
L2Z12_16590	COG3706	GGDEF domain
L2Z12_16590	COG4251	negative regulation of phosphorylation
L2Z12_16590	COG5001	Diguanylate cyclase
L2Z12_16600	COG1902	pentaerythritol trinitrate reductase activity
L2Z12_16600	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z12_16615	COG4269	membrane
L2Z12_16645	COG3209	COG3209 Rhs family protein
L2Z12_16685	COG1113	amino acid transport
L2Z12_16695	COG0531	amino acid
L2Z12_16715	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_16735	COG1113	amino acid transport
L2Z12_16750	COG0697	spore germination
L2Z12_16755	COG2721	sulfolactate sulfo-lyase activity
L2Z12_16760	COG2271	Major facilitator Superfamily
L2Z12_16765	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z12_16775	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_16780	COG2186	Transcriptional regulator
L2Z12_16820	COG0300	oxidoreductase activity
L2Z12_16830	COG1309	transcriptional regulator
L2Z12_16835	COG1741	Belongs to the pirin family
L2Z12_16850	COG2072	flavoprotein involved in K transport
L2Z12_16860	COG2252	PERMEase
L2Z12_16865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z12_16870	COG3038	cytochrome b561
L2Z12_16880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z12_16890	COG0527	aspartate kinase activity
L2Z12_16900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z12_16910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z12_16925	COG0667	Aldo Keto reductase
L2Z12_16940	COG1765	OsmC-like protein
L2Z12_16955	COG0542	response to heat
L2Z12_16990	COG2885	chlorophyll binding
L2Z12_17000	COG0625	glutathione transferase activity
L2Z12_17005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z12_17025	COG3634	alkyl hydroperoxide reductase activity
L2Z12_17035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z12_17045	COG0450	alkyl hydroperoxide reductase
L2Z12_17050	COG1643	Atp-dependent helicase
L2Z12_17065	COG2814	Major facilitator Superfamily
L2Z12_17070	COG3135	benzoate transporter
L2Z12_17075	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_17080	COG0543	2 iron, 2 sulfur cluster binding
L2Z12_17080	COG0633	Ferredoxin
L2Z12_17085	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z12_17090	COG4638	Rieske (2fe-2S)
L2Z12_17100	COG0583	DNA-binding transcription factor activity
L2Z12_17150	COG1570	exodeoxyribonuclease VII activity
L2Z12_17185	COG1278	Cold shock
L2Z12_17220	COG2814	Major facilitator Superfamily
L2Z12_17255	COG0517	IMP dehydrogenase activity
L2Z12_17255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z12_17260	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z12_17270	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z12_17275	COG1137	ATPase activity
L2Z12_17330	COG4122	O-methyltransferase activity
L2Z12_17340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z12_17355	COG1522	sequence-specific DNA binding
L2Z12_17360	COG5006	permease, DMT superfamily
L2Z12_17370	COG1560	Kdo2-lipid A biosynthetic process
L2Z12_17405	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z12_17485	COG0583	DNA-binding transcription factor activity
L2Z12_17490	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z12_17510	COG4770	biotin carboxylase activity
L2Z12_17515	COG0038	chloride channel
L2Z12_17530	COG1309	transcriptional regulator
L2Z12_17555	COG0439	Biotin carboxylase
L2Z12_17560	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z12_17580	COG0864	Transcriptional regulator
L2Z12_17590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z12_17595	COG1116	anion transmembrane transporter activity
L2Z12_17715	COG0590	tRNA wobble adenosine to inosine editing
L2Z12_17720	COG2807	transmembrane transport
L2Z12_17735	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z12_17745	COG0789	Transcriptional regulator
L2Z12_17755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z12_17775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z12_17785	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z12_17800	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_17810	COG0531	amino acid
L2Z12_17815	COG1760	l-serine dehydratase
L2Z12_17820	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_17820	COG2030	dehydratase
L2Z12_17825	COG3396	Phenylacetate-CoA oxygenase
L2Z12_17830	COG3460	Phenylacetate-CoA oxygenase
L2Z12_17835	COG3396	Phenylacetate-CoA oxygenase
L2Z12_17840	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z12_17845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z12_17850	COG1024	Enoyl-CoA hydratase
L2Z12_17855	COG1024	Enoyl-CoA hydratase
L2Z12_17860	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z12_17865	COG0183	Belongs to the thiolase family
L2Z12_17870	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z12_17875	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z12_17885	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z12_17925	COG0753	catalase activity
L2Z12_17930	COG3038	cytochrome b561
L2Z12_17950	COG2267	carboxylic ester hydrolase activity
L2Z12_17955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z12_17960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z12_17965	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_17975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z12_17985	COG1012	belongs to the aldehyde dehydrogenase family
L2Z12_17990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z12_17995	COG0583	DNA-binding transcription factor activity
L2Z12_18005	COG1414	Transcriptional regulator
L2Z12_18010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z12_18025	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z12_18030	COG3842	ATPase activity
L2Z12_18045	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z12_18050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z12_18055	COG2814	Major facilitator Superfamily
L2Z12_18060	COG1960	acyl-CoA dehydrogenase activity
L2Z12_18075	COG1024	Enoyl-CoA hydratase
L2Z12_18085	COG2814	Major facilitator Superfamily
L2Z12_18095	COG0183	Belongs to the thiolase family
L2Z12_18100	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z12_18105	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_18110	COG1024	Enoyl-CoA hydratase
L2Z12_18115	COG1960	acyl-CoA dehydrogenase activity
L2Z12_18120	COG2814	Major facilitator Superfamily
L2Z12_18125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z12_18130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z12_18140	COG2814	Major facilitator Superfamily
L2Z12_18150	COG1960	acyl-CoA dehydrogenase activity
L2Z12_18165	COG0583	DNA-binding transcription factor activity
L2Z12_18175	COG4770	biotin carboxylase activity
L2Z12_18180	COG1024	Enoyl-CoA hydratase
L2Z12_18185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z12_18190	COG1960	acyl-CoA dehydrogenase activity
L2Z12_18195	COG1309	transcriptional regulator
L2Z12_18200	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z12_18220	COG0583	DNA-binding transcription factor activity
L2Z12_18270	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z12_18310	COG2205	protein histidine kinase activity
L2Z12_18310	COG0784	Response regulator, receiver
L2Z12_18330	COG0765	amino acid transport
L2Z12_18335	COG0765	amino acid transport
L2Z12_18340	COG1126	abc transporter atp-binding protein
L2Z12_18345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z12_18350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z12_18365	COG1280	lysine exporter protein (LysE YggA)
L2Z12_18375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z12_18380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z12_18385	COG1045	serine acetyltransferase
L2Z12_18400	COG0583	DNA-binding transcription factor activity
L2Z12_18405	COG0625	glutathione transferase activity
L2Z12_18410	COG0625	glutathione transferase activity
L2Z12_18415	COG0583	DNA-binding transcription factor activity
L2Z12_18425	COG1346	cytolysis
L2Z12_18445	COG2814	Major facilitator Superfamily
L2Z12_18455	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z12_18460	COG3052	prosthetic group binding
L2Z12_18480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z12_18500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z12_18510	COG1294	oxidase, subunit
L2Z12_18515	COG1271	oxidase subunit
L2Z12_18535	COG0477	Major facilitator Superfamily
L2Z12_18545	COG4521	taurine ABC transporter
L2Z12_18550	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z12_18555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z12_18560	COG2175	clavaminate synthase activity
L2Z12_18570	COG1953	Uracil, thiamine, allantoin
L2Z12_18590	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z12_18605	COG0640	Transcriptional regulator
L2Z12_18610	COG0798	PFAM Bile acid sodium symporter
L2Z12_18615	COG0583	DNA-binding transcription factor activity
L2Z12_18630	COG3634	alkyl hydroperoxide reductase activity
L2Z12_18670	COG0436	Aminotransferase
L2Z12_18680	COG0386	Belongs to the glutathione peroxidase family
L2Z12_18720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z12_18745	COG0012	GTP binding
L2Z12_18750	COG2011	ABC-type metal ion transport system permease component
L2Z12_18755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z12_18765	COG1464	Belongs to the NlpA lipoprotein family
L2Z12_18795	COG0765	amino acid transport
L2Z12_18805	COG1126	abc transporter atp-binding protein
L2Z12_18815	COG1522	sequence-specific DNA binding
L2Z12_18860	COG0583	DNA-binding transcription factor activity
L2Z12_18870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z12_18880	COG0697	spore germination
L2Z12_18935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z12_18935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z12_18980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z12_18990	COG2353	YceI-like domain
L2Z12_19020	COG0506	proline dehydrogenase activity
L2Z12_19020	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z12_19020	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z12_19030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z12_19045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z12_19065	COG1132	(ABC) transporter
L2Z12_19070	COG3122	Protein conserved in bacteria
L2Z12_19075	COG3619	membrane
L2Z12_19085	COG0640	Transcriptional regulator
L2Z12_19095	COG2850	peptidyl-arginine hydroxylation
L2Z12_19100	COG0424	maF-like protein
L2Z12_19120	COG0191	fructose-bisphosphate aldolase activity
L2Z12_19125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z12_19140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z12_19150	COG1192	Involved in chromosome partitioning
L2Z12_19155	COG1475	DNA binding
L2Z12_19160	COG0811	peptide transport
L2Z12_19170	COG1132	(ABC) transporter
L2Z12_19175	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z12_19195	COG0084	hydrolase, TatD family'
L2Z12_19260	COG0776	regulation of translation
L2Z12_19290	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z12_19390	COG5484	DNA packaging
L2Z12_19390	COG3728	DNA packaging
L2Z12_19490	COG3293	Transposase