locus-tag	class	description
L2Z13_00005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z13_00030	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z13_00045	COG0824	Thioesterase
L2Z13_00050	COG1454	alcohol dehydrogenase
L2Z13_00060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z13_00090	COG0069	glutamate synthase activity
L2Z13_00295	COG5410	chromosome segregation
L2Z13_00385	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z13_00400	COG1196	nuclear chromosome segregation
L2Z13_00400	COG0741	lytic transglycosylase activity
L2Z13_00400	COG0739	heme binding
L2Z13_00470	COG2814	Major facilitator Superfamily
L2Z13_00485	COG0511	ligase activity, forming carbon-carbon bonds
L2Z13_00505	COG1116	anion transmembrane transporter activity
L2Z13_00505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z13_00510	COG0745	RESPONSE REGULATOR receiver
L2Z13_00520	COG2146	nitrite reductase [NAD(P)H] activity
L2Z13_00520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z13_00525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z13_00530	COG0243	molybdopterin cofactor binding
L2Z13_00540	COG0243	molybdopterin cofactor binding
L2Z13_00545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z13_00560	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z13_00560	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z13_00565	COG0303	'Molybdopterin
L2Z13_00575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z13_00580	COG0697	spore germination
L2Z13_00600	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z13_00605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z13_00660	COG2204	response regulator
L2Z13_00665	COG3852	Histidine kinase
L2Z13_00690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z13_00695	COG0575	Belongs to the CDS family
L2Z13_00710	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z13_00730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z13_00745	COG2137	regulation of response to DNA damage stimulus
L2Z13_00755	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z13_00760	COG1011	Hydrolase
L2Z13_00785	COG1522	sequence-specific DNA binding
L2Z13_00795	COG1113	amino acid transport
L2Z13_00815	COG0659	secondary active sulfate transmembrane transporter activity
L2Z13_00820	COG2135	peptidase activity
L2Z13_00845	COG4372	Transposase
L2Z13_00870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z13_00870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z13_00870	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z13_00875	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z13_00880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z13_00880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z13_00910	COG0024	Methionine aminopeptidase
L2Z13_00915	COG0583	DNA-binding transcription factor activity
L2Z13_00925	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z13_00930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z13_00935	COG0516	GMP reductase activity
L2Z13_00935	COG0517	IMP dehydrogenase activity
L2Z13_00960	COG0552	protein localization to endoplasmic reticulum
L2Z13_00970	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z13_00980	COG4890	Cyd operon protein YbgT
L2Z13_00985	COG1294	oxidase, subunit
L2Z13_01000	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z13_01010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z13_01015	COG4774	siderophore transport
L2Z13_01030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z13_01035	COG0569	domain protein
L2Z13_01040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z13_01070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z13_01075	COG0542	response to heat
L2Z13_01100	COG1902	pentaerythritol trinitrate reductase activity
L2Z13_01100	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z13_01145	COG2323	membrane
L2Z13_01150	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z13_01160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z13_01165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z13_01170	COG0183	Belongs to the thiolase family
L2Z13_01175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z13_01180	COG0596	Alpha beta hydrolase
L2Z13_01185	COG2271	Major facilitator Superfamily
L2Z13_01190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z13_01195	COG3485	protocatechuate 3,4-dioxygenase
L2Z13_01200	COG3485	protocatechuate 3,4-dioxygenase
L2Z13_01205	COG0710	3-dehydroquinate dehydratase activity
L2Z13_01210	COG3420	alginic acid biosynthetic process
L2Z13_01215	COG3659	wide pore channel activity
L2Z13_01220	COG4993	Dehydrogenase
L2Z13_01230	COG2391	methyltransferase activity
L2Z13_01245	COG1414	Transcriptional regulator
L2Z13_01250	COG0583	DNA-binding transcription factor activity
L2Z13_01255	COG1960	acyl-CoA dehydrogenase activity
L2Z13_01280	COG2814	Major facilitator Superfamily
L2Z13_01290	COG0154	amidase activity
L2Z13_01310	COG4638	Rieske (2fe-2S)
L2Z13_01320	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_01330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z13_01340	COG3733	amine oxidase
L2Z13_01350	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_01355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z13_01360	COG0183	Belongs to the thiolase family
L2Z13_01365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z13_01370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z13_01380	COG4829	muconolactone delta-isomerase
L2Z13_01385	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z13_01390	COG0583	DNA-binding transcription factor activity
L2Z13_01400	COG2186	Transcriptional regulator
L2Z13_01420	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_01435	COG1902	pentaerythritol trinitrate reductase activity
L2Z13_01435	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z13_01450	COG0789	Transcriptional regulator
L2Z13_01480	COG1309	transcriptional regulator
L2Z13_01485	COG0583	DNA-binding transcription factor activity
L2Z13_01490	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_01495	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_01500	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_01510	COG1960	acyl-CoA dehydrogenase activity
L2Z13_01520	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z13_01570	COG2188	Transcriptional regulator
L2Z13_01585	COG0583	DNA-binding transcription factor activity
L2Z13_01620	COG1566	PFAM secretion protein HlyD family protein
L2Z13_01650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z13_01670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z13_01710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z13_01715	COG2814	Major facilitator Superfamily
L2Z13_01725	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z13_01735	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_01740	COG3384	dioxygenase
L2Z13_01750	COG3971	2-oxopent-4-enoate hydratase activity
L2Z13_01765	COG0477	Major facilitator Superfamily
L2Z13_01770	COG1960	acyl-CoA dehydrogenase activity
L2Z13_01775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z13_01780	COG1846	Transcriptional regulator
L2Z13_01785	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_01790	COG0129	dihydroxy-acid dehydratase activity
L2Z13_01800	COG0583	DNA-binding transcription factor activity
L2Z13_01805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z13_01815	COG2084	Dehydrogenase
L2Z13_01820	COG2207	Transcriptional regulator
L2Z13_01825	COG1064	alcohol dehydrogenase
L2Z13_01835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z13_01840	COG1120	ATPase activity
L2Z13_01860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z13_01955	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_01960	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_01970	COG2207	Transcriptional regulator
L2Z13_01980	COG2205	protein histidine kinase activity
L2Z13_01985	COG0745	RESPONSE REGULATOR receiver
L2Z13_01990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z13_01995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z13_02065	COG3539	Fimbrial protein
L2Z13_02090	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z13_02100	COG0753	catalase activity
L2Z13_02120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z13_02130	COG3293	Transposase
L2Z13_02195	COG3433	isochorismatase activity
L2Z13_02195	COG1535	isochorismatase
L2Z13_02200	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_02205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z13_02210	COG4149	molybdate abc transporter
L2Z13_02215	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z13_02225	COG4638	Rieske (2fe-2S)
L2Z13_02230	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z13_02235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z13_02235	COG0543	2 iron, 2 sulfur cluster binding
L2Z13_02250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z13_02260	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_02275	COG2207	Transcriptional regulator
L2Z13_02280	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_02285	COG2610	gluconate transmembrane transporter activity
L2Z13_02290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z13_02320	COG0583	DNA-binding transcription factor activity
L2Z13_02335	COG2031	fatty acid transporter
L2Z13_02340	COG0183	Belongs to the thiolase family
L2Z13_02345	COG0583	DNA-binding transcription factor activity
L2Z13_02350	COG0583	DNA-binding transcription factor activity
L2Z13_02365	COG1027	Aspartate ammonia-lyase
L2Z13_02375	COG0477	Major facilitator Superfamily
L2Z13_02395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z13_02400	COG4521	taurine ABC transporter
L2Z13_02415	COG2188	Transcriptional regulator
L2Z13_02425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z13_02430	COG1733	regulation of RNA biosynthetic process
L2Z13_02435	COG3708	Transcriptional regulator
L2Z13_02435	COG2207	Transcriptional regulator
L2Z13_02450	COG0730	response to heat
L2Z13_02475	COG3781	membrane
L2Z13_02480	COG1063	alcohol dehydrogenase
L2Z13_02490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z13_02495	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z13_02500	COG0022	dehydrogenase e1 component
L2Z13_02505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z13_02510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z13_02540	COG0133	tryptophan synthase activity
L2Z13_02550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z13_02585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z13_02610	COG2226	methyltransferase
L2Z13_02665	COG0842	Transport permease protein
L2Z13_02670	COG0842	Transport permease protein
L2Z13_02675	COG1131	(ABC) transporter
L2Z13_02690	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z13_02695	COG4773	Receptor
L2Z13_02715	COG0730	response to heat
L2Z13_02720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z13_02735	COG0406	alpha-ribazole phosphatase activity
L2Z13_02740	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z13_02755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z13_02785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z13_02795	COG4264	IucA IucC family
L2Z13_02800	COG4264	IucA IucC family
L2Z13_02805	COG2814	Major facilitator Superfamily
L2Z13_02820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z13_02835	COG1960	acyl-CoA dehydrogenase activity
L2Z13_02840	COG1960	acyl-CoA dehydrogenase activity
L2Z13_02845	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z13_02850	COG2207	Transcriptional regulator
L2Z13_02855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z13_02860	COG0776	regulation of translation
L2Z13_02885	COG0822	iron-sulfur transferase activity
L2Z13_02890	COG0316	Belongs to the HesB IscA family
L2Z13_02920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z13_02940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z13_02945	COG0702	epimerase
L2Z13_02980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z13_02990	COG0339	signal peptide processing
L2Z13_03035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z13_03040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z13_03075	COG0776	regulation of translation
L2Z13_03140	COG0084	hydrolase, TatD family'
L2Z13_03160	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z13_03165	COG1132	(ABC) transporter
L2Z13_03175	COG0811	peptide transport
L2Z13_03180	COG1475	DNA binding
L2Z13_03185	COG1192	Involved in chromosome partitioning
L2Z13_03195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z13_03210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z13_03215	COG0191	fructose-bisphosphate aldolase activity
L2Z13_03235	COG0424	maF-like protein
L2Z13_03240	COG2850	peptidyl-arginine hydroxylation
L2Z13_03250	COG0640	Transcriptional regulator
L2Z13_03260	COG3619	membrane
L2Z13_03265	COG3122	Protein conserved in bacteria
L2Z13_03270	COG1132	(ABC) transporter
L2Z13_03290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z13_03295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z13_03305	COG0506	proline dehydrogenase activity
L2Z13_03305	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z13_03305	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z13_03310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z13_03325	COG3698	Phosphodiester glycosidase
L2Z13_03335	COG2353	YceI-like domain
L2Z13_03345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z13_03395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z13_03395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z13_03420	COG3539	Fimbrial protein
L2Z13_03425	COG3121	Chaperone
L2Z13_03445	COG0697	spore germination
L2Z13_03455	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z13_03465	COG0583	DNA-binding transcription factor activity
L2Z13_03485	COG1309	transcriptional regulator
L2Z13_03500	COG1522	sequence-specific DNA binding
L2Z13_03510	COG1126	abc transporter atp-binding protein
L2Z13_03515	COG0765	amino acid transport
L2Z13_03520	COG0765	amino acid transport
L2Z13_03550	COG1464	Belongs to the NlpA lipoprotein family
L2Z13_03560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z13_03565	COG2011	ABC-type metal ion transport system permease component
L2Z13_03570	COG0012	GTP binding
L2Z13_03595	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z13_03635	COG0386	Belongs to the glutathione peroxidase family
L2Z13_03645	COG0436	Aminotransferase
L2Z13_03685	COG3634	alkyl hydroperoxide reductase activity
L2Z13_03700	COG0583	DNA-binding transcription factor activity
L2Z13_03705	COG0798	PFAM Bile acid sodium symporter
L2Z13_03710	COG0640	Transcriptional regulator
L2Z13_03725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z13_03735	COG0583	DNA-binding transcription factor activity
L2Z13_03745	COG1953	Uracil, thiamine, allantoin
L2Z13_03755	COG2175	clavaminate synthase activity
L2Z13_03760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z13_03765	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z13_03770	COG4521	taurine ABC transporter
L2Z13_03780	COG0477	Major facilitator Superfamily
L2Z13_03800	COG1271	oxidase subunit
L2Z13_03805	COG1294	oxidase, subunit
L2Z13_03815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z13_03835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z13_03855	COG3052	prosthetic group binding
L2Z13_03860	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z13_03870	COG0583	DNA-binding transcription factor activity
L2Z13_03880	COG2814	Major facilitator Superfamily
L2Z13_03900	COG1346	cytolysis
L2Z13_03910	COG0583	DNA-binding transcription factor activity
L2Z13_03915	COG0625	glutathione transferase activity
L2Z13_03920	COG0625	glutathione transferase activity
L2Z13_03925	COG0583	DNA-binding transcription factor activity
L2Z13_03940	COG1045	serine acetyltransferase
L2Z13_03945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z13_03950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z13_03955	COG1280	lysine exporter protein (LysE YggA)
L2Z13_03970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z13_03975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z13_03985	COG0765	amino acid transport
L2Z13_03990	COG0765	amino acid transport
L2Z13_04010	COG2205	protein histidine kinase activity
L2Z13_04010	COG0784	Response regulator, receiver
L2Z13_04030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z13_04055	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_04105	COG0583	DNA-binding transcription factor activity
L2Z13_04125	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z13_04130	COG1309	transcriptional regulator
L2Z13_04135	COG1960	acyl-CoA dehydrogenase activity
L2Z13_04140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z13_04145	COG1024	Enoyl-CoA hydratase
L2Z13_04150	COG4770	biotin carboxylase activity
L2Z13_04160	COG0583	DNA-binding transcription factor activity
L2Z13_04175	COG1960	acyl-CoA dehydrogenase activity
L2Z13_04185	COG2814	Major facilitator Superfamily
L2Z13_04195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z13_04200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z13_04205	COG2814	Major facilitator Superfamily
L2Z13_04210	COG1960	acyl-CoA dehydrogenase activity
L2Z13_04215	COG1024	Enoyl-CoA hydratase
L2Z13_04220	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_04225	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z13_04230	COG0183	Belongs to the thiolase family
L2Z13_04240	COG2814	Major facilitator Superfamily
L2Z13_04250	COG1024	Enoyl-CoA hydratase
L2Z13_04265	COG1960	acyl-CoA dehydrogenase activity
L2Z13_04270	COG2814	Major facilitator Superfamily
L2Z13_04275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z13_04280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z13_04295	COG3842	ATPase activity
L2Z13_04300	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z13_04315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z13_04320	COG1414	Transcriptional regulator
L2Z13_04330	COG0583	DNA-binding transcription factor activity
L2Z13_04335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z13_04340	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_04350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z13_04360	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_04365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z13_04370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z13_04375	COG2267	carboxylic ester hydrolase activity
L2Z13_04395	COG3038	cytochrome b561
L2Z13_04400	COG0753	catalase activity
L2Z13_04405	COG2271	Major facilitator Superfamily
L2Z13_04410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z13_04415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z13_04440	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z13_04450	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z13_04455	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z13_04460	COG0183	Belongs to the thiolase family
L2Z13_04465	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z13_04470	COG1024	Enoyl-CoA hydratase
L2Z13_04475	COG1024	Enoyl-CoA hydratase
L2Z13_04480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z13_04485	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z13_04490	COG3396	Phenylacetate-CoA oxygenase
L2Z13_04495	COG3460	Phenylacetate-CoA oxygenase
L2Z13_04500	COG3396	Phenylacetate-CoA oxygenase
L2Z13_04505	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_04505	COG2030	dehydratase
L2Z13_04510	COG1760	l-serine dehydratase
L2Z13_04515	COG0531	amino acid
L2Z13_04520	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_04545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z13_04565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z13_04575	COG0789	Transcriptional regulator
L2Z13_04585	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z13_04600	COG2807	transmembrane transport
L2Z13_04605	COG0590	tRNA wobble adenosine to inosine editing
L2Z13_04655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z13_04695	COG3657	addiction module killer protein
L2Z13_04700	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z13_04710	COG2801	Transposase and inactivated derivatives
L2Z13_04725	COG0488	(ABC) transporter
L2Z13_04730	COG3173	Aminoglycoside phosphotransferase
L2Z13_04755	COG2223	nitrite transmembrane transporter activity
L2Z13_04765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z13_04770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z13_04775	COG1960	acyl-CoA dehydrogenase activity
L2Z13_04790	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z13_04795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z13_04800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z13_04820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z13_04825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z13_04830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z13_04865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z13_04875	COG0174	glutamine synthetase
L2Z13_04890	COG0582	viral genome integration into host DNA
L2Z13_04955	COG0739	heme binding
L2Z13_04955	COG0741	lytic transglycosylase activity
L2Z13_04955	COG1196	nuclear chromosome segregation
L2Z13_05000	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z13_05115	COG5410	chromosome segregation
L2Z13_05325	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z13_05330	COG0308	aminopeptidase N
L2Z13_05360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z13_05370	COG0302	gtp cyclohydrolase
L2Z13_05390	COG3739	integral membrane protein
L2Z13_05405	COG1169	isochorismate synthase
L2Z13_05415	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z13_05420	COG1132	(ABC) transporter
L2Z13_05425	COG1132	(ABC) transporter
L2Z13_05440	COG3433	isochorismatase activity
L2Z13_05440	COG1535	isochorismatase
L2Z13_05445	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z13_05450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z13_05460	COG4774	siderophore transport
L2Z13_05465	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z13_05470	COG4604	ABC transporter, ATP-binding protein
L2Z13_05475	COG4605	iron ion homeostasis
L2Z13_05480	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z13_05485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z13_05500	COG2964	Protein conserved in bacteria
L2Z13_05510	COG1741	Belongs to the pirin family
L2Z13_05535	COG2130	NADP-dependent
L2Z13_05545	COG2879	small protein
L2Z13_05550	COG1966	Carbon starvation protein
L2Z13_05570	COG4943	cyclic-guanylate-specific phosphodiesterase activity
L2Z13_05595	COG1067	ATP-dependent peptidase activity
L2Z13_05600	COG0583	DNA-binding transcription factor activity
L2Z13_05625	COG1686	Belongs to the peptidase S11 family
L2Z13_05630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z13_05665	COG0616	signal peptide processing
L2Z13_05670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z13_05680	COG0573	inorganic phosphate transmembrane transporter activity
L2Z13_05685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z13_05690	COG1113	amino acid transport
L2Z13_05695	COG3961	Belongs to the TPP enzyme family
L2Z13_05700	COG1522	sequence-specific DNA binding
L2Z13_05710	COG0076	glutamate decarboxylase activity
L2Z13_05715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z13_05730	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z13_05740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z13_05775	COG0352	thiamine-phosphate diphosphorylase activity
L2Z13_05800	COG0612	Peptidase, M16
L2Z13_05810	COG1823	symporter activity
L2Z13_05815	COG0583	DNA-binding transcription factor activity
L2Z13_05820	COG0477	Major facilitator Superfamily
L2Z13_05845	COG1187	pseudouridine synthase activity
L2Z13_05860	COG1686	Belongs to the peptidase S11 family
L2Z13_05865	COG1252	NADH dehydrogenase
L2Z13_05875	COG0415	Belongs to the DNA photolyase family
L2Z13_05890	COG1215	transferase activity, transferring glycosyl groups
L2Z13_05920	COG2070	2-Nitropropane dioxygenase
L2Z13_05975	COG0556	nucleotide-excision repair
L2Z13_05995	COG0436	Aminotransferase
L2Z13_06010	COG0443	Heat shock 70 kDa protein
L2Z13_06040	COG4221	oxidoreductase activity
L2Z13_06050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z13_06055	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z13_06065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z13_06080	COG0681	Belongs to the peptidase S26 family
L2Z13_06095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z13_06115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z13_06120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z13_06125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z13_06135	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z13_06140	COG4208	sulfate ABC transporter
L2Z13_06145	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z13_06150	COG0583	DNA-binding transcription factor activity
L2Z13_06155	COG4625	pathogenesis
L2Z13_06170	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z13_06185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z13_06195	COG1051	belongs to the nudix hydrolase family
L2Z13_06195	COG1056	cytidyltransferase-related domain
L2Z13_06200	COG1024	Enoyl-CoA hydratase
L2Z13_06210	COG2814	Major facilitator Superfamily
L2Z13_06215	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z13_06215	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z13_06235	COG1473	amidohydrolase
L2Z13_06240	COG0824	Thioesterase
L2Z13_06260	COG0823	Involved in the tonB-independent uptake of proteins
L2Z13_06280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z13_06315	COG0628	permease
L2Z13_06325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z13_06330	COG0596	Alpha beta hydrolase
L2Z13_06335	COG0616	signal peptide processing
L2Z13_06335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z13_06345	COG2333	competence protein COMEC
L2Z13_06345	COG0658	competence protein
L2Z13_06350	COG1136	(ABC) transporter
L2Z13_06355	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z13_06390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z13_06410	COG0463	Glycosyl transferase, family 2
L2Z13_06440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z13_06445	COG1280	lysine exporter protein (LysE YggA)
L2Z13_06455	COG0019	diaminopimelate decarboxylase activity
L2Z13_06465	COG1113	amino acid transport
L2Z13_06480	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z13_06490	COG3339	Conserved Protein
L2Z13_06495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z13_06500	COG0243	molybdopterin cofactor binding
L2Z13_06505	COG1929	Belongs to the glycerate kinase type-1 family
L2Z13_06520	COG0778	Nitroreductase
L2Z13_06540	COG3811	Belongs to the UPF0386 family
L2Z13_06565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z13_06580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z13_06600	COG0741	lytic transglycosylase activity
L2Z13_06620	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z13_06625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z13_06650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z13_06655	COG1597	lipid kinase activity
L2Z13_06670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z13_06675	COG0477	Major facilitator Superfamily
L2Z13_06735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z13_06740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z13_06765	COG0505	Belongs to the CarA family
L2Z13_06785	COG0251	oxidation-reduction process
L2Z13_06795	COG0589	response to stress
L2Z13_06810	COG2843	Capsule synthesis protein
L2Z13_06830	COG2321	neutral zinc metallopeptidase
L2Z13_06835	COG2354	Protein conserved in bacteria
L2Z13_06855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z13_06880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z13_06885	COG1053	succinate dehydrogenase
L2Z13_06890	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z13_06895	COG2009	succinate dehydrogenase
L2Z13_06930	COG2921	Belongs to the UPF0250 family
L2Z13_06935	COG0321	lipoyl(octanoyl) transferase activity
L2Z13_06950	COG0531	amino acid
L2Z13_06960	COG1733	regulation of RNA biosynthetic process
L2Z13_06965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z13_06970	COG1648	precorrin-2 dehydrogenase activity
L2Z13_06970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z13_06985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z13_07015	COG0671	phosphoesterase, PA-phosphatase related
L2Z13_07020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z13_07030	COG1538	Outer membrane efflux protein
L2Z13_07035	COG0393	Putative heavy-metal-binding
L2Z13_07040	COG0393	Putative heavy-metal-binding
L2Z13_07050	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_07060	COG0525	valine-tRNA ligase activity
L2Z13_07080	COG0583	DNA-binding transcription factor activity
L2Z13_07085	COG0004	ammonium transporteR
L2Z13_07095	COG0642	Histidine kinase
L2Z13_07100	COG0745	RESPONSE REGULATOR receiver
L2Z13_07105	COG2194	sulfuric ester hydrolase activity
L2Z13_07125	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z13_07140	COG2315	Protein conserved in bacteria
L2Z13_07145	COG0142	geranyltranstransferase activity
L2Z13_07150	COG2828	Protein conserved in bacteria
L2Z13_07155	COG1113	amino acid transport
L2Z13_07175	COG2207	Transcriptional regulator
L2Z13_07200	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z13_07210	COG0560	Phosphoserine phosphatase
L2Z13_07220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z13_07230	COG1530	ribonuclease E activity
L2Z13_07235	COG0424	maF-like protein
L2Z13_07240	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z13_07245	COG1792	Involved in formation and maintenance of cell shape
L2Z13_07250	COG1077	Cell shape determining protein MreB Mrl
L2Z13_07255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z13_07265	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z13_07290	COG3590	peptidase
L2Z13_07300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z13_07305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z13_07310	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z13_07315	COG1115	amino acid carrier protein
L2Z13_07335	COG2814	Major facilitator Superfamily
L2Z13_07340	COG1289	transmembrane transporter activity
L2Z13_07350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z13_07390	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z13_07395	COG2832	Protein of unknown function (DUF454)
L2Z13_07405	COG3293	Transposase
L2Z13_07410	COG5510	response to toxic substance
L2Z13_07425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z13_07440	COG0840	transmembrane signaling receptor activity
L2Z13_07480	COG3422	double-strand break repair
L2Z13_07485	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z13_07490	COG3189	MarR family transcriptional regulator
L2Z13_07500	COG0354	folic acid binding
L2Z13_07505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z13_07515	COG0679	Auxin Efflux Carrier
L2Z13_07520	COG1902	pentaerythritol trinitrate reductase activity
L2Z13_07525	COG4772	TonB-dependent receptor
L2Z13_07530	COG2094	Belongs to the DNA glycosylase MPG family
L2Z13_07555	COG1217	gtp-binding protein TYPA
L2Z13_07560	COG2233	PERMEase
L2Z13_07570	COG0833	amino acid
L2Z13_07575	COG1690	Belongs to the RtcB family
L2Z13_07585	COG2885	chlorophyll binding
L2Z13_07585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z13_07595	COG0183	Belongs to the thiolase family
L2Z13_07615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z13_07635	COG2207	Transcriptional regulator
L2Z13_07640	COG0183	Belongs to the thiolase family
L2Z13_07670	COG1272	protein, Hemolysin III
L2Z13_07675	COG0477	Major facilitator Superfamily
L2Z13_07690	COG0450	alkyl hydroperoxide reductase
L2Z13_07710	COG0285	dihydrofolate synthase activity
L2Z13_07760	COG2096	Adenosyltransferase
L2Z13_07780	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z13_07785	COG0745	RESPONSE REGULATOR receiver
L2Z13_07790	COG2205	protein histidine kinase activity
L2Z13_07800	COG1960	acyl-CoA dehydrogenase activity
L2Z13_07805	COG1960	acyl-CoA dehydrogenase activity
L2Z13_07855	COG1215	transferase activity, transferring glycosyl groups
L2Z13_07870	COG1091	dTDP-4-dehydrorhamnose reductase activity
L2Z13_07890	COG0726	polysaccharide deacetylase
L2Z13_07905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z13_07910	COG2205	protein histidine kinase activity
L2Z13_07945	COG1862	Preprotein translocase
L2Z13_07955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z13_07960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z13_07970	COG3781	membrane
L2Z13_07975	COG0613	PHP domain protein
L2Z13_07985	COG2350	Protein conserved in bacteria
L2Z13_08015	COG1607	acyl-coa hydrolase
L2Z13_08075	COG2199	diguanylate cyclase activity
L2Z13_08085	COG1408	metallophosphoesterase
L2Z13_08090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z13_08100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z13_08120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z13_08125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z13_08140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z13_08150	COG2969	positive regulation of protein catabolic process
L2Z13_08190	COG1960	acyl-CoA dehydrogenase activity
L2Z13_08195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z13_08210	COG1309	transcriptional regulator
L2Z13_08215	COG1960	acyl-CoA dehydrogenase activity
L2Z13_08260	COG1183	phosphatidylcholine synthase activity
L2Z13_08265	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z13_08295	COG0741	lytic transglycosylase activity
L2Z13_08295	COG1196	nuclear chromosome segregation
L2Z13_08295	COG0739	heme binding
L2Z13_08305	COG1702	phosphate starvation-inducible protein PhoH
L2Z13_08340	COG1295	ribonuclease BN
L2Z13_08345	COG0697	spore germination
L2Z13_08355	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z13_08400	COG0557	exoribonuclease II activity
L2Z13_08405	COG0339	signal peptide processing
L2Z13_08410	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z13_08440	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z13_08445	COG1960	acyl-CoA dehydrogenase activity
L2Z13_08600	COG0626	cystathionine gamma-synthase activity
L2Z13_08605	COG0433	COG0433 Predicted ATPase
L2Z13_08615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z13_08615	COG1017	nitric oxide dioxygenase activity
L2Z13_08620	COG1959	2 iron, 2 sulfur cluster binding
L2Z13_08635	COG1301	dicarboxylic acid transport
L2Z13_08640	COG1946	Acyl-CoA thioesterase
L2Z13_08660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z13_08665	COG1040	competence protein
L2Z13_08670	COG0494	nUDIX hydrolase
L2Z13_08680	COG0598	Magnesium transport protein CorA
L2Z13_08690	COG2854	intermembrane phospholipid transfer
L2Z13_08700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z13_08705	COG1127	ABC transporter
L2Z13_08715	COG0513	Belongs to the DEAD box helicase family
L2Z13_08735	COG0408	coproporphyrinogen oxidase activity
L2Z13_08750	COG1960	acyl-CoA dehydrogenase activity
L2Z13_08760	COG1983	PspC domain protein
L2Z13_08765	COG0517	IMP dehydrogenase activity
L2Z13_08810	COG0583	DNA-binding transcription factor activity
L2Z13_08850	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_08860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z13_08865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z13_08870	COG0833	amino acid
L2Z13_08900	COG1192	Involved in chromosome partitioning
L2Z13_08905	COG0628	permease
L2Z13_08930	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z13_08935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z13_08945	COG0277	FAD linked oxidase domain protein
L2Z13_08950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z13_08975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z13_08980	COG5380	lipid catabolic process
L2Z13_09000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z13_09050	COG0194	GDP metabolic process
L2Z13_09065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z13_09085	COG3307	-O-antigen
L2Z13_09105	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z13_09110	COG1704	LemA family
L2Z13_09120	COG0493	'glutamate synthase
L2Z13_09125	COG0069	glutamate synthase activity
L2Z13_09125	COG0070	glutamate synthase
L2Z13_09125	COG0067	glutamate synthase
L2Z13_09175	COG2226	methyltransferase
L2Z13_09190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z13_09195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z13_09240	COG0833	amino acid
L2Z13_09260	COG0582	viral genome integration into host DNA
L2Z13_09325	COG4372	Transposase
L2Z13_09460	COG0488	(ABC) transporter
L2Z13_09465	COG2873	o-acetylhomoserine
L2Z13_09470	COG4221	oxidoreductase activity
L2Z13_09475	COG0659	secondary active sulfate transmembrane transporter activity
L2Z13_09500	COG0427	acetyl-CoA hydrolase
L2Z13_09530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z13_09560	COG2329	Antibiotic biosynthesis monooxygenase
L2Z13_09575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z13_09635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2Z13_09645	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z13_09650	COG1733	regulation of RNA biosynthetic process
L2Z13_09665	COG0667	Aldo Keto reductase
L2Z13_09685	COG0583	DNA-binding transcription factor activity
L2Z13_09690	COG2814	Major facilitator Superfamily
L2Z13_09720	COG1335	isochorismatase
L2Z13_09730	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_09735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z13_09745	COG1113	amino acid transport
L2Z13_09755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z13_09770	COG2814	Major facilitator Superfamily
L2Z13_09780	COG0351	phosphomethylpyrimidine kinase
L2Z13_09780	COG0352	thiamine-phosphate diphosphorylase activity
L2Z13_09780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z13_09800	COG1309	transcriptional regulator
L2Z13_09805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z13_09820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z13_09830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z13_09835	COG3162	membrane
L2Z13_09840	COG2198	Histidine kinase
L2Z13_09840	COG0784	Response regulator, receiver
L2Z13_09840	COG2205	protein histidine kinase activity
L2Z13_09865	COG1522	sequence-specific DNA binding
L2Z13_09870	COG1335	isochorismatase
L2Z13_09875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z13_09885	COG0668	transmembrane transport
L2Z13_09890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z13_09895	COG1519	Transferase
L2Z13_09900	COG1902	pentaerythritol trinitrate reductase activity
L2Z13_09920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z13_09945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z13_09945	COG0426	domain, Protein
L2Z13_09950	COG4774	siderophore transport
L2Z13_09955	COG2119	membrane
L2Z13_09965	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z13_09975	COG4942	peptidase
L2Z13_09990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z13_10000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z13_10020	COG0189	ligase activity
L2Z13_10040	COG0708	Exodeoxyribonuclease III
L2Z13_10045	COG1393	Belongs to the ArsC family
L2Z13_10060	COG3706	GGDEF domain
L2Z13_10100	COG2233	PERMEase
L2Z13_10110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z13_10120	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z13_10130	COG3150	esterase
L2Z13_10185	COG2918	glutathione biosynthetic process
L2Z13_10200	COG2733	membrane
L2Z13_10205	COG0436	Aminotransferase
L2Z13_10210	COG0534	Mate efflux family protein
L2Z13_10310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z13_10315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z13_10325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z13_10375	COG2826	transposase and inactivated derivatives, IS30 family
L2Z13_10385	COG2015	COG2015, Alkyl sulfatase and related hydrolases
L2Z13_10390	COG2826	transposase and inactivated derivatives, IS30 family
L2Z13_10425	COG1484	DNA-dependent DNA replication
L2Z13_10435	COG1324	tolerance protein
L2Z13_10440	COG0673	inositol 2-dehydrogenase activity
L2Z13_10460	COG2826	transposase and inactivated derivatives, IS30 family
L2Z13_10480	COG1484	DNA-dependent DNA replication
L2Z13_10490	COG4584	PFAM Integrase catalytic
L2Z13_10520	COG0732	type I restriction modification DNA specificity domain
L2Z13_10525	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
L2Z13_10535	COG2826	transposase and inactivated derivatives, IS30 family
L2Z13_10540	COG2015	COG2015, Alkyl sulfatase and related hydrolases
L2Z13_10550	COG2826	transposase and inactivated derivatives, IS30 family
L2Z13_10570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z13_10585	COG0010	Belongs to the arginase family
L2Z13_10615	COG2188	Transcriptional regulator
L2Z13_10625	COG0523	cobalamin synthesis protein
L2Z13_10635	COG1113	amino acid transport
L2Z13_10645	COG0625	glutathione transferase activity
L2Z13_10665	COG1683	Conserved Protein
L2Z13_10670	COG0534	Mate efflux family protein
L2Z13_10675	COG0385	Bile acid
L2Z13_10680	COG1335	isochorismatase
L2Z13_10685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z13_10705	COG2116	formate transmembrane transporter activity
L2Z13_10710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z13_10715	COG2133	pyrroloquinoline quinone binding
L2Z13_10720	COG2983	Belongs to the UPF0260 family
L2Z13_10740	COG1194	a g-specific adenine glycosylase
L2Z13_10755	COG2818	Glycosylase
L2Z13_10760	COG1064	alcohol dehydrogenase
L2Z13_10765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z13_10780	COG0583	DNA-binding transcription factor activity
L2Z13_10785	COG0656	L-ascorbic acid biosynthetic process
L2Z13_10790	COG2814	Major facilitator Superfamily
L2Z13_10825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z13_10840	COG2233	PERMEase
L2Z13_10845	COG0583	DNA-binding transcription factor activity
L2Z13_10870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L2Z13_10880	COG0733	neurotransmitter:sodium symporter activity
L2Z13_10920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z13_10925	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z13_10930	COG0596	Alpha beta hydrolase
L2Z13_10955	COG0488	(ABC) transporter
L2Z13_10960	COG0586	Pfam SNARE associated Golgi protein
L2Z13_10970	COG0187	DNA topoisomerase II activity
L2Z13_10980	COG0592	DNA-directed DNA polymerase activity
L2Z13_11005	COG0706	membrane insertase activity
L2Z13_11020	COG1230	cation diffusion facilitator family transporter
L2Z13_11025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z13_11040	COG0402	S-adenosylhomocysteine deaminase activity
L2Z13_11050	COG0754	glutathionylspermidine amidase activity
L2Z13_11060	COG0861	Integral membrane protein TerC family
L2Z13_11065	COG0671	phosphoesterase, PA-phosphatase related
L2Z13_11075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z13_11090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z13_11095	COG2951	lytic endotransglycosylase activity
L2Z13_11125	COG0583	DNA-binding transcription factor activity
L2Z13_11145	COG0657	acetylesterase activity
L2Z13_11150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z13_11190	COG1047	Peptidyl-prolyl cis-trans
L2Z13_11200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z13_11205	COG0196	riboflavin kinase activity
L2Z13_11215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z13_11220	COG1309	transcriptional regulator
L2Z13_11225	COG1116	anion transmembrane transporter activity
L2Z13_11230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z13_11235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z13_11240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z13_11245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z13_11265	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_11270	COG0546	phosphoglycolate phosphatase activity
L2Z13_11325	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z13_11330	COG0728	peptidoglycan biosynthetic process
L2Z13_11360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z13_11370	COG5039	Polysaccharide pyruvyl transferase
L2Z13_11395	COG1215	transferase activity, transferring glycosyl groups
L2Z13_11405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z13_11410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z13_11425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z13_11430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z13_11440	COG2186	Transcriptional regulator
L2Z13_11450	COG0277	FAD linked oxidase domain protein
L2Z13_11455	COG1448	Aminotransferase
L2Z13_11465	COG1802	Transcriptional regulator
L2Z13_11480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z13_11525	COG0564	pseudouridine synthase activity
L2Z13_11565	COG0251	oxidation-reduction process
L2Z13_11570	COG1113	amino acid transport
L2Z13_11575	COG1113	amino acid transport
L2Z13_11595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z13_11600	COG1960	acyl-CoA dehydrogenase activity
L2Z13_11605	COG1024	Enoyl-CoA hydratase
L2Z13_11610	COG1024	Enoyl-CoA hydratase
L2Z13_11615	COG0477	Major facilitator Superfamily
L2Z13_11620	COG3916	Acyl-homoserine-lactone synthase
L2Z13_11630	COG2197	response regulator
L2Z13_11640	COG1960	acyl-CoA dehydrogenase activity
L2Z13_11645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z13_11645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z13_11645	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z13_11645	COG3321	synthase
L2Z13_11685	COG0271	Belongs to the BolA IbaG family
L2Z13_11695	COG1192	Involved in chromosome partitioning
L2Z13_11710	COG0586	Pfam SNARE associated Golgi protein
L2Z13_11715	COG2259	Doxx family
L2Z13_11720	COG4399	Belongs to the UPF0754 family
L2Z13_11725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z13_11725	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z13_11770	COG0281	malic enzyme
L2Z13_11775	COG2837	iron assimilation
L2Z13_11780	COG1280	lysine exporter protein (LysE YggA)
L2Z13_11785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z13_11790	COG1121	(ABC) transporter
L2Z13_11855	COG0386	Belongs to the glutathione peroxidase family
L2Z13_11870	COG1309	transcriptional regulator
L2Z13_11875	COG0697	spore germination
L2Z13_11885	COG0758	DNA mediated transformation
L2Z13_11955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z13_11965	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z13_12005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z13_12015	COG0477	Major facilitator Superfamily
L2Z13_12025	COG1253	flavin adenine dinucleotide binding
L2Z13_12035	COG2860	membrane
L2Z13_12040	COG0477	Major facilitator Superfamily
L2Z13_12050	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z13_12065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z13_12085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z13_12145	COG0589	response to stress
L2Z13_12150	COG0659	secondary active sulfate transmembrane transporter activity
L2Z13_12170	COG0347	Belongs to the P(II) protein family
L2Z13_12175	COG0004	ammonium transporteR
L2Z13_12185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z13_12185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z13_12225	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z13_12230	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z13_12235	COG0793	Belongs to the peptidase S41A family
L2Z13_12250	COG2197	response regulator
L2Z13_12260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z13_12270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z13_12275	COG4974	Belongs to the 'phage' integrase family
L2Z13_12300	COG0772	Belongs to the SEDS family
L2Z13_12305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z13_12310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z13_12315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z13_12340	COG0697	spore germination
L2Z13_12365	COG3275	phosphorelay sensor kinase activity
L2Z13_12375	COG0181	hydroxymethylbilane synthase activity
L2Z13_12420	COG1716	ATPase activity
L2Z13_12425	COG0546	phosphoglycolate phosphatase activity
L2Z13_12525	COG2056	Na+-H+ antiporter family
L2Z13_12540	COG0326	Molecular chaperone. Has ATPase activity
L2Z13_12555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z13_12610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z13_12615	COG2169	Transcriptional regulator
L2Z13_12615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z13_12645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z13_12655	COG0497	DNA recombination
L2Z13_12670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z13_12680	COG0237	dephospho-CoA kinase activity
L2Z13_12685	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z13_12745	COG0195	Participates in both transcription termination and antitermination
L2Z13_12760	COG1320	monovalent cation:proton antiporter activity
L2Z13_12765	COG2212	antiporter activity
L2Z13_12770	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z13_12775	COG0651	ATP synthesis coupled electron transport
L2Z13_12780	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z13_12785	COG2111	Na H antiporter
L2Z13_12785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z13_12800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z13_12815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z13_12825	COG2226	methyltransferase
L2Z13_12845	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z13_12850	COG1074	ATP-dependent DNA helicase activity
L2Z13_12855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z13_12860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z13_12875	COG0598	Magnesium transport protein CorA
L2Z13_12880	COG0789	Transcriptional regulator
L2Z13_12885	COG0484	heat shock protein binding
L2Z13_12900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z13_12900	COG0475	glutathione-regulated potassium exporter activity
L2Z13_12905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z13_12925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z13_12935	COG4535	Mg2 and Co2 transporter CorC
L2Z13_12940	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z13_12950	COG0644	oxidoreductase
L2Z13_12950	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z13_12960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z13_12975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z13_12980	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z13_12990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z13_12990	COG0493	'glutamate synthase
L2Z13_13020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z13_13035	COG0534	Mate efflux family protein
L2Z13_13045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z13_13050	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_13055	COG0583	DNA-binding transcription factor activity
L2Z13_13070	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z13_13075	COG1530	ribonuclease E activity
L2Z13_13085	COG0546	phosphoglycolate phosphatase activity
L2Z13_13090	COG2378	regulation of single-species biofilm formation
L2Z13_13095	COG0625	glutathione transferase activity
L2Z13_13105	COG0583	DNA-binding transcription factor activity
L2Z13_13160	COG0473	3-isopropylmalate dehydrogenase activity
L2Z13_13190	COG0252	asparaginase activity
L2Z13_13215	COG1301	dicarboxylic acid transport
L2Z13_13225	COG1560	Kdo2-lipid A biosynthetic process
L2Z13_13230	COG1280	lysine exporter protein (LysE YggA)
L2Z13_13235	COG0488	(ABC) transporter
L2Z13_13240	COG2900	Belongs to the SlyX family
L2Z13_13250	COG1733	regulation of RNA biosynthetic process
L2Z13_13275	COG0210	DNA helicase
L2Z13_13280	COG0724	RNA recognition motif
L2Z13_13300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z13_13300	COG4651	solute:proton antiporter activity
L2Z13_13325	COG0788	formyltetrahydrofolate deformylase activity
L2Z13_13425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z13_13425	COG2813	Specifically methylates the guanine in position
L2Z13_13435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z13_13465	COG0740	serine-type endopeptidase activity
L2Z13_13485	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z13_13485	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z13_13490	COG0280	phosphate acetyltransferase
L2Z13_13490	COG0857	belongs to the CobB CobQ family
L2Z13_13495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z13_13505	COG0800	Aldolase
L2Z13_13515	COG3265	gluconokinase activity
L2Z13_13520	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_13545	COG0793	Belongs to the peptidase S41A family
L2Z13_13580	COG1426	Protein conserved in bacteria
L2Z13_13620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z13_13630	COG1162	GTPase activity
L2Z13_13635	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z13_13650	COG1538	Outer membrane efflux protein
L2Z13_13655	COG1136	(ABC) transporter
L2Z13_13655	COG0577	efflux transmembrane transporter activity
L2Z13_13660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z13_13685	COG0028	Belongs to the TPP enzyme family
L2Z13_13690	COG0440	acetolactate synthase activity
L2Z13_13720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z13_13735	COG0084	hydrolase, TatD family'
L2Z13_13745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z13_13755	COG0583	DNA-binding transcription factor activity
L2Z13_13765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z13_13790	COG4372	Transposase
L2Z13_13865	COG2205	protein histidine kinase activity
L2Z13_13880	COG2132	Multicopper oxidase
L2Z13_13925	COG0640	Transcriptional regulator
L2Z13_13935	COG0798	PFAM Bile acid sodium symporter
L2Z13_13940	COG0431	NADPH-dependent FMN reductase
L2Z13_13945	COG0492	ferredoxin-NADP+ reductase activity
L2Z13_13950	COG2072	flavoprotein involved in K transport
L2Z13_13960	COG2814	Major facilitator Superfamily
L2Z13_13970	COG0697	spore germination
L2Z13_14000	COG3622	Belongs to the hyi family
L2Z13_14005	COG2084	Dehydrogenase
L2Z13_14010	COG1024	Enoyl-CoA hydratase
L2Z13_14015	COG0784	Response regulator, receiver
L2Z13_14015	COG2205	protein histidine kinase activity
L2Z13_14015	COG5002	protein histidine kinase activity
L2Z13_14035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z13_14045	COG3956	TIGRFAM MazG family protein
L2Z13_14050	COG1555	photosystem II stabilization
L2Z13_14055	COG0617	tRNA 3'-terminal CCA addition
L2Z13_14060	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z13_14080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z13_14085	COG3028	Belongs to the UPF0307 family
L2Z13_14090	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z13_14105	COG0625	glutathione transferase activity
L2Z13_14110	COG1238	metal cluster binding
L2Z13_14155	COG0072	phenylalanine-tRNA ligase activity
L2Z13_14185	COG0248	Ppx GppA phosphatase
L2Z13_14195	COG0037	tRNA processing
L2Z13_14210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L2Z13_14210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L2Z13_14235	COG1764	response to oxidative stress
L2Z13_14240	COG1846	Transcriptional regulator
L2Z13_14250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z13_14310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z13_14315	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z13_14320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z13_14345	COG3293	Transposase
L2Z13_14385	COG1214	PFAM Peptidase M22, glycoprotease
L2Z13_14410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z13_14415	COG0561	phosphatase activity
L2Z13_14425	COG2132	Multicopper oxidase
L2Z13_14445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z13_14450	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z13_14455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z13_14485	COG1063	alcohol dehydrogenase
L2Z13_14490	COG0583	DNA-binding transcription factor activity
L2Z13_14495	COG1960	acyl-CoA dehydrogenase activity
L2Z13_14500	COG2814	Major facilitator Superfamily
L2Z13_14505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z13_14510	COG1309	transcriptional regulator
L2Z13_14525	COG1053	succinate dehydrogenase
L2Z13_14530	COG0583	DNA-binding transcription factor activity
L2Z13_14545	COG0583	DNA-binding transcription factor activity
L2Z13_14555	COG0583	DNA-binding transcription factor activity
L2Z13_14570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z13_14610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z13_14630	COG0745	RESPONSE REGULATOR receiver
L2Z13_14645	COG3706	GGDEF domain
L2Z13_14670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z13_14700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z13_14705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z13_14725	COG0583	DNA-binding transcription factor activity
L2Z13_14745	COG0668	transmembrane transport
L2Z13_14755	COG2081	HI0933 family
L2Z13_14760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z13_14790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z13_14790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z13_14800	COG0489	protein tyrosine kinase activity
L2Z13_14850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z13_14860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z13_14875	COG0730	response to heat
L2Z13_14885	COG1196	nuclear chromosome segregation
L2Z13_14905	COG2223	nitrite transmembrane transporter activity
L2Z13_14910	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z13_14920	COG0596	Alpha beta hydrolase
L2Z13_14920	COG2226	methyltransferase
L2Z13_14920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z13_14935	COG4106	trans-aconitate 2-methyltransferase activity
L2Z13_14950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z13_14955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z13_14960	COG0009	L-threonylcarbamoyladenylate synthase
L2Z13_14965	COG3101	peptidyl-lysine hydroxylation
L2Z13_14970	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z13_14995	COG1652	LysM domain
L2Z13_15000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z13_15000	COG0352	thiamine-phosphate diphosphorylase activity
L2Z13_15000	COG0351	phosphomethylpyrimidine kinase
L2Z13_15010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z13_15040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z13_15070	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z13_15085	COG0358	DNA primase activity
L2Z13_15095	COG0564	pseudouridine synthase activity
L2Z13_15120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z13_15140	COG0583	DNA-binding transcription factor activity
L2Z13_15145	COG0473	3-isopropylmalate dehydrogenase activity
L2Z13_15155	COG0657	acetylesterase activity
L2Z13_15165	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_15185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z13_15185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z13_15200	COG1981	membrane
L2Z13_15245	COG0456	acetyltransferase
L2Z13_15255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z13_15260	COG0492	ferredoxin-NADP+ reductase activity
L2Z13_15265	COG1674	ftsk spoiiie
L2Z13_15270	COG1280	lysine exporter protein (LysE YggA)
L2Z13_15290	COG2894	cell division
L2Z13_15305	COG0204	Acyl-transferase
L2Z13_15310	COG2885	chlorophyll binding
L2Z13_15315	COG0210	DNA helicase
L2Z13_15325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z13_15340	COG0121	glutamine amidotransferase
L2Z13_15360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z13_15365	COG0735	belongs to the Fur family
L2Z13_15390	COG0420	3'-5' exonuclease activity
L2Z13_15410	COG1090	epimerase
L2Z13_15425	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z13_15435	COG2814	Major facilitator Superfamily
L2Z13_15440	COG0405	Gamma-glutamyltransferase
L2Z13_15450	COG0582	viral genome integration into host DNA
L2Z13_15545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z13_15610	COG0477	Major facilitator Superfamily
L2Z13_15615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z13_15640	COG0531	amino acid
L2Z13_15645	COG2040	homocysteine
L2Z13_15670	COG1309	transcriptional regulator
L2Z13_15675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z13_15680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z13_15690	COG1607	acyl-coa hydrolase
L2Z13_15700	COG0523	cobalamin synthesis protein
L2Z13_15710	COG4681	YaeQ
L2Z13_15720	COG0726	polysaccharide deacetylase
L2Z13_15720	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z13_15725	COG1215	transferase activity, transferring glycosyl groups
L2Z13_15735	COG1024	Enoyl-CoA hydratase
L2Z13_15750	COG1414	Transcriptional regulator
L2Z13_15770	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_15785	COG2271	Major facilitator Superfamily
L2Z13_15795	COG2267	carboxylic ester hydrolase activity
L2Z13_15800	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_15810	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_15815	COG0028	Belongs to the TPP enzyme family
L2Z13_15825	COG0477	Major facilitator Superfamily
L2Z13_15830	COG0242	peptide deformylase activity
L2Z13_15835	COG2066	Belongs to the glutaminase family
L2Z13_15840	COG2207	Transcriptional regulator
L2Z13_15845	COG2223	nitrite transmembrane transporter activity
L2Z13_15860	COG0583	DNA-binding transcription factor activity
L2Z13_15865	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_15870	COG2271	Major facilitator Superfamily
L2Z13_15875	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z13_15880	COG3958	Transketolase
L2Z13_15890	COG0306	phosphate transporter
L2Z13_15910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z13_15955	COG4181	ATPase activity
L2Z13_15960	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z13_15990	COG0583	DNA-binding transcription factor activity
L2Z13_16000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z13_16005	COG1773	rubredoxin
L2Z13_16055	COG2851	Citrate transporter
L2Z13_16060	COG1253	flavin adenine dinucleotide binding
L2Z13_16100	COG0804	urea catabolic process
L2Z13_16110	COG0830	nickel cation binding
L2Z13_16125	COG0742	ribosomal rna small subunit methyltransferase
L2Z13_16130	COG0768	penicillin binding
L2Z13_16155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z13_16160	COG2878	Part of a membrane complex involved in electron transport
L2Z13_16165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z13_16175	COG3384	dioxygenase
L2Z13_16460	COG0739	heme binding
L2Z13_16460	COG1196	nuclear chromosome segregation
L2Z13_16460	COG0741	lytic transglycosylase activity
L2Z13_16590	COG0006	proline dipeptidase activity
L2Z13_16595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z13_16600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z13_16620	COG1279	arginine transmembrane transporter activity
L2Z13_16625	COG0583	DNA-binding transcription factor activity
L2Z13_16665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z13_16670	COG0741	lytic transglycosylase activity
L2Z13_16670	COG1388	LysM domain
L2Z13_16670	COG0741	lytic transglycosylase activity
L2Z13_16670	COG1388	LysM domain
L2Z13_16680	COG4174	ABC transporter (Permease)
L2Z13_16685	COG4239	(ABC) transporter, permease
L2Z13_16690	COG4172	Belongs to the ABC transporter superfamily
L2Z13_16710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z13_16720	COG2203	Gaf domain
L2Z13_16720	COG4251	negative regulation of phosphorylation
L2Z13_16720	COG5001	Diguanylate cyclase
L2Z13_16720	COG3706	GGDEF domain
L2Z13_16730	COG1902	pentaerythritol trinitrate reductase activity
L2Z13_16730	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z13_16745	COG4269	membrane
L2Z13_16765	COG3209	COG3209 Rhs family protein
L2Z13_16800	COG1113	amino acid transport
L2Z13_16810	COG0531	amino acid
L2Z13_16830	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_16850	COG1113	amino acid transport
L2Z13_16885	COG0697	spore germination
L2Z13_16890	COG2721	sulfolactate sulfo-lyase activity
L2Z13_16895	COG2271	Major facilitator Superfamily
L2Z13_16900	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z13_16910	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_16915	COG2186	Transcriptional regulator
L2Z13_16940	COG1960	acyl-CoA dehydrogenase activity
L2Z13_16950	COG1012	belongs to the aldehyde dehydrogenase family
L2Z13_16955	COG1024	Enoyl-CoA hydratase
L2Z13_16960	COG2814	Major facilitator Superfamily
L2Z13_16975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z13_16990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z13_17035	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L2Z13_17040	COG2072	flavoprotein involved in K transport
L2Z13_17045	COG0300	oxidoreductase activity
L2Z13_17055	COG1309	transcriptional regulator
L2Z13_17060	COG1741	Belongs to the pirin family
L2Z13_17075	COG2072	flavoprotein involved in K transport
L2Z13_17085	COG2252	PERMEase
L2Z13_17090	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z13_17095	COG3038	cytochrome b561
L2Z13_17105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z13_17115	COG0527	aspartate kinase activity
L2Z13_17125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z13_17140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z13_17155	COG0667	Aldo Keto reductase
L2Z13_17170	COG1765	OsmC-like protein
L2Z13_17185	COG0542	response to heat
L2Z13_17220	COG2885	chlorophyll binding
L2Z13_17230	COG0625	glutathione transferase activity
L2Z13_17235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z13_17260	COG3634	alkyl hydroperoxide reductase activity
L2Z13_17270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z13_17275	COG3293	Transposase
L2Z13_17285	COG0450	alkyl hydroperoxide reductase
L2Z13_17290	COG1643	Atp-dependent helicase
L2Z13_17305	COG2814	Major facilitator Superfamily
L2Z13_17310	COG3135	benzoate transporter
L2Z13_17315	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z13_17320	COG0633	Ferredoxin
L2Z13_17320	COG0543	2 iron, 2 sulfur cluster binding
L2Z13_17330	COG4638	Rieske (2fe-2S)
L2Z13_17340	COG0583	DNA-binding transcription factor activity
L2Z13_17350	COG2871	sodium ion transport
L2Z13_17435	COG1570	exodeoxyribonuclease VII activity
L2Z13_17470	COG1278	Cold shock
L2Z13_17505	COG2814	Major facilitator Superfamily
L2Z13_17545	COG0517	IMP dehydrogenase activity
L2Z13_17545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z13_17550	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z13_17560	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z13_17565	COG1137	ATPase activity
L2Z13_17600	COG4122	O-methyltransferase activity
L2Z13_17610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z13_17625	COG1522	sequence-specific DNA binding
L2Z13_17640	COG1560	Kdo2-lipid A biosynthetic process
L2Z13_17645	COG0598	Magnesium transport protein CorA
L2Z13_17665	COG2814	Major facilitator Superfamily
L2Z13_17685	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z13_17705	COG1011	Hydrolase
L2Z13_17775	COG0583	DNA-binding transcription factor activity
L2Z13_17815	COG0024	Methionine aminopeptidase
L2Z13_17820	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z13_17835	COG2207	Transcriptional regulator
L2Z13_17860	COG2951	lytic endotransglycosylase activity
L2Z13_17865	COG0772	Belongs to the SEDS family
L2Z13_17880	COG0842	Transport permease protein
L2Z13_17885	COG1131	(ABC) transporter
L2Z13_17930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z13_17945	COG4215	(ABC) transporter
L2Z13_17950	COG4160	amino acid transport
L2Z13_17955	COG4598	ABC transporter
L2Z13_17965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z13_17970	COG0826	peptidase U32
L2Z13_17975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z13_17990	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z13_18000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z13_18015	COG0642	Histidine kinase
L2Z13_18025	COG0494	nUDIX hydrolase
L2Z13_18035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z13_18040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z13_18045	COG3139	Protein of unknown function (DUF1315)
L2Z13_18050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z13_18055	COG1301	dicarboxylic acid transport
L2Z13_18060	COG1960	acyl-CoA dehydrogenase activity
L2Z13_18065	COG2819	hydrolase of the alpha beta superfamily
L2Z13_18075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z13_18085	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z13_18090	COG1234	tRNA 3'-trailer cleavage
L2Z13_18125	COG2363	Small membrane protein
L2Z13_18150	COG0513	Belongs to the DEAD box helicase family
L2Z13_18160	COG0778	Nitroreductase
L2Z13_18190	COG1286	toxin biosynthetic process
L2Z13_18215	COG4783	chaperone-mediated protein folding
L2Z13_18220	COG1610	YqeY-like protein
L2Z13_18290	COG3210	domain, Protein
L2Z13_18290	COG3210	domain, Protein
L2Z13_18375	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z13_18400	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z13_18405	COG0786	glutamate:sodium symporter activity
L2Z13_18415	COG2186	Transcriptional regulator
L2Z13_18465	COG0477	Major facilitator Superfamily
L2Z13_18490	COG2985	domain, Protein
L2Z13_18505	COG2995	paraquat-inducible protein a
L2Z13_18510	COG3008	intermembrane lipid transfer
L2Z13_18510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z13_18520	COG2351	hydroxyisourate hydrolase activity
L2Z13_18560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2Z13_18570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2Z13_18575	COG0642	Histidine kinase
L2Z13_18580	COG0745	RESPONSE REGULATOR receiver
L2Z13_18600	COG1794	racemase activity, acting on amino acids and derivatives
L2Z13_18630	COG1301	dicarboxylic acid transport
L2Z13_18640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z13_18645	COG2011	ABC-type metal ion transport system permease component
L2Z13_18650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z13_18655	COG1464	Belongs to the NlpA lipoprotein family
L2Z13_18660	COG0151	Belongs to the GarS family
L2Z13_18665	COG0138	bifunctional purine biosynthesis protein purh
L2Z13_18670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z13_18700	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z13_18710	COG1305	Transglutaminase-like
L2Z13_18720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z13_18725	COG0305	Participates in initiation and elongation during chromosome replication
L2Z13_18750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z13_18760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z13_18765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z13_18790	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z13_18790	COG0726	polysaccharide deacetylase
L2Z13_18795	COG1215	transferase activity, transferring glycosyl groups
L2Z13_18800	COG3658	cytochrome
L2Z13_18810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z13_18855	COG1960	acyl-CoA dehydrogenase activity
L2Z13_18860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z13_18865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z13_18890	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z13_18895	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z13_18905	COG2205	protein histidine kinase activity
L2Z13_18910	COG0745	RESPONSE REGULATOR receiver
L2Z13_18915	COG3293	Transposase
L2Z13_18920	COG0174	glutamine synthetase
L2Z13_18940	COG0729	surface antigen
L2Z13_18965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z13_18970	COG2814	Major facilitator Superfamily
L2Z13_18985	COG0583	DNA-binding transcription factor activity
L2Z13_19000	COG1187	pseudouridine synthase activity
L2Z13_19020	COG0802	atpase or kinase
L2Z13_19025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z13_19035	COG1923	regulation of RNA biosynthetic process
L2Z13_19040	COG0697	spore germination
L2Z13_19065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z13_19070	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z13_19070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z13_19075	COG4302	ethanolamine ammonia-lyase activity
L2Z13_19080	COG4303	Ethanolamine ammonia lyase large subunit
L2Z13_19085	COG0531	amino acid
L2Z13_19110	COG1454	alcohol dehydrogenase
L2Z13_19115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z13_19140	COG0308	aminopeptidase N
L2Z13_19180	COG1605	Chorismate mutase
L2Z13_19200	COG1309	transcriptional regulator
L2Z13_19210	COG0668	transmembrane transport
L2Z13_19220	COG3293	Transposase
L2Z13_19245	COG4773	Receptor
L2Z13_19265	COG0488	(ABC) transporter
L2Z13_19270	COG0589	response to stress
L2Z13_19295	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z13_19305	COG3135	benzoate transporter
L2Z13_19310	COG1522	sequence-specific DNA binding
L2Z13_19320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z13_19325	COG0583	DNA-binding transcription factor activity
L2Z13_19335	COG0183	Belongs to the thiolase family
L2Z13_19345	COG2030	dehydratase