locus-tag	class	description
L2Z14_00005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z14_00020	COG0497	DNA recombination
L2Z14_00030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z14_00060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z14_00060	COG2169	Transcriptional regulator
L2Z14_00065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z14_00125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z14_00140	COG0326	Molecular chaperone. Has ATPase activity
L2Z14_00155	COG2056	Na+-H+ antiporter family
L2Z14_00160	COG0596	Alpha beta hydrolase
L2Z14_00255	COG0546	phosphoglycolate phosphatase activity
L2Z14_00260	COG1716	ATPase activity
L2Z14_00305	COG0181	hydroxymethylbilane synthase activity
L2Z14_00315	COG3275	phosphorelay sensor kinase activity
L2Z14_00335	COG1538	Outer membrane efflux protein
L2Z14_00340	COG0697	spore germination
L2Z14_00365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z14_00370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z14_00375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z14_00380	COG0772	Belongs to the SEDS family
L2Z14_00405	COG4974	Belongs to the 'phage' integrase family
L2Z14_00410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z14_00420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z14_00430	COG2197	response regulator
L2Z14_00445	COG0793	Belongs to the peptidase S41A family
L2Z14_00450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z14_00455	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z14_00495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z14_00495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z14_00505	COG0004	ammonium transporteR
L2Z14_00510	COG0347	Belongs to the P(II) protein family
L2Z14_00520	COG0606	chelatase, subunit chli
L2Z14_00530	COG0235	Class ii aldolase
L2Z14_00535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z14_00555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z14_00570	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z14_00580	COG0477	Major facilitator Superfamily
L2Z14_00585	COG2860	membrane
L2Z14_00590	COG3012	SEC-C Motif Domain Protein
L2Z14_00595	COG1253	flavin adenine dinucleotide binding
L2Z14_00605	COG2814	Major facilitator Superfamily
L2Z14_00615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z14_00655	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z14_00665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z14_00735	COG0758	DNA mediated transformation
L2Z14_00745	COG0697	spore germination
L2Z14_00750	COG1309	transcriptional regulator
L2Z14_00765	COG0386	Belongs to the glutathione peroxidase family
L2Z14_00835	COG1121	(ABC) transporter
L2Z14_00840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z14_00845	COG1280	lysine exporter protein (LysE YggA)
L2Z14_00850	COG2837	iron assimilation
L2Z14_00860	COG0281	malic enzyme
L2Z14_00905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z14_00905	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z14_00910	COG4399	Belongs to the UPF0754 family
L2Z14_00915	COG2259	Doxx family
L2Z14_00920	COG0586	Pfam SNARE associated Golgi protein
L2Z14_00935	COG1192	Involved in chromosome partitioning
L2Z14_00945	COG0271	Belongs to the BolA IbaG family
L2Z14_00965	COG1024	Enoyl-CoA hydratase
L2Z14_00970	COG1024	Enoyl-CoA hydratase
L2Z14_00975	COG1960	acyl-CoA dehydrogenase activity
L2Z14_00980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z14_01000	COG1113	amino acid transport
L2Z14_01005	COG1113	amino acid transport
L2Z14_01010	COG0251	oxidation-reduction process
L2Z14_01050	COG0564	pseudouridine synthase activity
L2Z14_01120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z14_01135	COG1802	Transcriptional regulator
L2Z14_01145	COG1448	Aminotransferase
L2Z14_01150	COG0277	FAD linked oxidase domain protein
L2Z14_01160	COG2186	Transcriptional regulator
L2Z14_01170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z14_01185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z14_01200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z14_01205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z14_01230	COG2244	polysaccharide biosynthetic process
L2Z14_01235	COG2089	acid synthase
L2Z14_01250	COG1083	cytidylyl-transferase
L2Z14_01255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L2Z14_01260	COG1086	Polysaccharide biosynthesis protein
L2Z14_01265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z14_01270	COG1596	polysaccharide export
L2Z14_01295	COG0728	peptidoglycan biosynthetic process
L2Z14_01300	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z14_01360	COG0546	phosphoglycolate phosphatase activity
L2Z14_01365	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_01385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z14_01390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z14_01395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z14_01400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z14_01405	COG1116	anion transmembrane transporter activity
L2Z14_01410	COG1309	transcriptional regulator
L2Z14_01415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z14_01425	COG0196	riboflavin kinase activity
L2Z14_01430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z14_01440	COG1047	Peptidyl-prolyl cis-trans
L2Z14_01480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z14_01485	COG0657	acetylesterase activity
L2Z14_01495	COG3328	transposase activity
L2Z14_01510	COG0583	DNA-binding transcription factor activity
L2Z14_01540	COG2951	lytic endotransglycosylase activity
L2Z14_01545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z14_01560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z14_01570	COG0671	phosphoesterase, PA-phosphatase related
L2Z14_01575	COG0861	Integral membrane protein TerC family
L2Z14_01585	COG0754	glutathionylspermidine amidase activity
L2Z14_01595	COG0402	S-adenosylhomocysteine deaminase activity
L2Z14_01610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z14_01615	COG1230	cation diffusion facilitator family transporter
L2Z14_01630	COG0706	membrane insertase activity
L2Z14_01655	COG0592	DNA-directed DNA polymerase activity
L2Z14_01665	COG0187	DNA topoisomerase II activity
L2Z14_01675	COG0586	Pfam SNARE associated Golgi protein
L2Z14_01680	COG0488	(ABC) transporter
L2Z14_01705	COG0596	Alpha beta hydrolase
L2Z14_01710	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z14_01715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z14_01755	COG0733	neurotransmitter:sodium symporter activity
L2Z14_01790	COG0583	DNA-binding transcription factor activity
L2Z14_01795	COG2233	PERMEase
L2Z14_01810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z14_01845	COG2814	Major facilitator Superfamily
L2Z14_01850	COG0656	L-ascorbic acid biosynthetic process
L2Z14_01855	COG0583	DNA-binding transcription factor activity
L2Z14_01870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z14_01875	COG1064	alcohol dehydrogenase
L2Z14_01880	COG2818	Glycosylase
L2Z14_01895	COG1194	a g-specific adenine glycosylase
L2Z14_01915	COG2983	Belongs to the UPF0260 family
L2Z14_01920	COG2133	pyrroloquinoline quinone binding
L2Z14_01925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z14_01930	COG2116	formate transmembrane transporter activity
L2Z14_01950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z14_01955	COG1335	isochorismatase
L2Z14_01960	COG0385	Bile acid
L2Z14_01965	COG0534	Mate efflux family protein
L2Z14_01970	COG1683	Conserved Protein
L2Z14_01990	COG0625	glutathione transferase activity
L2Z14_02000	COG1113	amino acid transport
L2Z14_02010	COG0523	cobalamin synthesis protein
L2Z14_02020	COG2188	Transcriptional regulator
L2Z14_02050	COG0010	Belongs to the arginase family
L2Z14_02065	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z14_02080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z14_02090	COG1061	Type III restriction enzyme res subunit
L2Z14_02095	COG1002	Type II restriction enzyme, methylase subunits
L2Z14_02100	COG1002	Type II restriction enzyme, methylase subunits
L2Z14_02135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z14_02145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z14_02150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z14_02235	COG0534	Mate efflux family protein
L2Z14_02240	COG0436	Aminotransferase
L2Z14_02245	COG2733	membrane
L2Z14_02260	COG2918	glutathione biosynthetic process
L2Z14_02310	COG3150	esterase
L2Z14_02320	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_02325	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z14_02335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z14_02345	COG2233	PERMEase
L2Z14_02350	COG2351	hydroxyisourate hydrolase activity
L2Z14_02385	COG3706	GGDEF domain
L2Z14_02400	COG1393	Belongs to the ArsC family
L2Z14_02405	COG0708	Exodeoxyribonuclease III
L2Z14_02430	COG0189	ligase activity
L2Z14_02450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z14_02460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z14_02475	COG4942	peptidase
L2Z14_02485	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z14_02495	COG2119	membrane
L2Z14_02500	COG4774	siderophore transport
L2Z14_02505	COG0426	domain, Protein
L2Z14_02505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z14_02530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z14_02550	COG1902	pentaerythritol trinitrate reductase activity
L2Z14_02555	COG1519	Transferase
L2Z14_02560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z14_02565	COG0668	transmembrane transport
L2Z14_02575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z14_02580	COG1335	isochorismatase
L2Z14_02585	COG1522	sequence-specific DNA binding
L2Z14_02610	COG0784	Response regulator, receiver
L2Z14_02610	COG2198	Histidine kinase
L2Z14_02610	COG2205	protein histidine kinase activity
L2Z14_02615	COG3162	membrane
L2Z14_02620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z14_02630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z14_02645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z14_02650	COG1309	transcriptional regulator
L2Z14_02670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z14_02670	COG0352	thiamine-phosphate diphosphorylase activity
L2Z14_02670	COG0351	phosphomethylpyrimidine kinase
L2Z14_02680	COG2814	Major facilitator Superfamily
L2Z14_02695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z14_02705	COG1113	amino acid transport
L2Z14_02715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z14_02720	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_02730	COG1335	isochorismatase
L2Z14_02760	COG2814	Major facilitator Superfamily
L2Z14_02765	COG0583	DNA-binding transcription factor activity
L2Z14_02805	COG0305	Participates in initiation and elongation during chromosome replication
L2Z14_02840	COG0582	viral genome integration into host DNA
L2Z14_02895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z14_02910	COG2329	Antibiotic biosynthesis monooxygenase
L2Z14_02925	COG1132	(ABC) transporter
L2Z14_02945	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z14_02975	COG0427	acetyl-CoA hydrolase
L2Z14_03000	COG0659	secondary active sulfate transmembrane transporter activity
L2Z14_03005	COG4221	oxidoreductase activity
L2Z14_03015	COG0488	(ABC) transporter
L2Z14_03080	COG0833	amino acid
L2Z14_03125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z14_03130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z14_03145	COG2226	methyltransferase
L2Z14_03195	COG0067	glutamate synthase
L2Z14_03195	COG0070	glutamate synthase
L2Z14_03195	COG0069	glutamate synthase activity
L2Z14_03200	COG0493	'glutamate synthase
L2Z14_03210	COG1704	LemA family
L2Z14_03215	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z14_03245	COG3307	-O-antigen
L2Z14_03265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z14_03280	COG0194	GDP metabolic process
L2Z14_03310	COG3328	transposase activity
L2Z14_03340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z14_03360	COG5380	lipid catabolic process
L2Z14_03365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z14_03390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z14_03395	COG0277	FAD linked oxidase domain protein
L2Z14_03405	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z14_03410	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z14_03425	COG1289	transmembrane transporter activity
L2Z14_03435	COG0628	permease
L2Z14_03440	COG1192	Involved in chromosome partitioning
L2Z14_03470	COG0833	amino acid
L2Z14_03475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z14_03480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z14_03490	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_03575	COG0517	IMP dehydrogenase activity
L2Z14_03580	COG1983	PspC domain protein
L2Z14_03590	COG1960	acyl-CoA dehydrogenase activity
L2Z14_03605	COG0408	coproporphyrinogen oxidase activity
L2Z14_03625	COG0513	Belongs to the DEAD box helicase family
L2Z14_03635	COG1127	ABC transporter
L2Z14_03640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z14_03650	COG2854	intermembrane phospholipid transfer
L2Z14_03660	COG0598	Magnesium transport protein CorA
L2Z14_03670	COG0494	nUDIX hydrolase
L2Z14_03675	COG1040	competence protein
L2Z14_03680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z14_03700	COG1946	Acyl-CoA thioesterase
L2Z14_03705	COG1301	dicarboxylic acid transport
L2Z14_03720	COG1959	2 iron, 2 sulfur cluster binding
L2Z14_03725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z14_03725	COG1017	nitric oxide dioxygenase activity
L2Z14_03735	COG0433	COG0433 Predicted ATPase
L2Z14_03740	COG0626	cystathionine gamma-synthase activity
L2Z14_03895	COG1960	acyl-CoA dehydrogenase activity
L2Z14_03900	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z14_03930	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z14_03935	COG0339	signal peptide processing
L2Z14_03940	COG0557	exoribonuclease II activity
L2Z14_03970	COG3328	transposase activity
L2Z14_03995	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z14_04000	COG2169	Transcriptional regulator
L2Z14_04010	COG1295	ribonuclease BN
L2Z14_04045	COG1702	phosphate starvation-inducible protein PhoH
L2Z14_04055	COG0739	heme binding
L2Z14_04055	COG0741	lytic transglycosylase activity
L2Z14_04055	COG1196	nuclear chromosome segregation
L2Z14_04085	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z14_04090	COG1183	phosphatidylcholine synthase activity
L2Z14_04135	COG1960	acyl-CoA dehydrogenase activity
L2Z14_04155	COG3328	transposase activity
L2Z14_04165	COG2969	positive regulation of protein catabolic process
L2Z14_04175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z14_04185	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
L2Z14_04190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z14_04195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z14_04215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z14_04225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z14_04230	COG1408	metallophosphoesterase
L2Z14_04240	COG2199	diguanylate cyclase activity
L2Z14_04300	COG1607	acyl-coa hydrolase
L2Z14_04330	COG2350	Protein conserved in bacteria
L2Z14_04340	COG0613	PHP domain protein
L2Z14_04345	COG3781	membrane
L2Z14_04355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z14_04360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z14_04370	COG1862	Preprotein translocase
L2Z14_04405	COG2205	protein histidine kinase activity
L2Z14_04410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z14_04430	COG0726	polysaccharide deacetylase
L2Z14_04435	COG0463	Glycosyl transferase, family 2
L2Z14_04440	COG0438	transferase activity, transferring glycosyl groups
L2Z14_04505	COG1960	acyl-CoA dehydrogenase activity
L2Z14_04510	COG1960	acyl-CoA dehydrogenase activity
L2Z14_04520	COG2205	protein histidine kinase activity
L2Z14_04525	COG0745	RESPONSE REGULATOR receiver
L2Z14_04530	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z14_04545	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z14_04550	COG2096	Adenosyltransferase
L2Z14_04555	COG4206	TonB-dependent receptor
L2Z14_04600	COG0285	dihydrofolate synthase activity
L2Z14_04620	COG0450	alkyl hydroperoxide reductase
L2Z14_04635	COG0477	Major facilitator Superfamily
L2Z14_04640	COG1272	protein, Hemolysin III
L2Z14_04670	COG0183	Belongs to the thiolase family
L2Z14_04675	COG2207	Transcriptional regulator
L2Z14_04695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z14_04715	COG0183	Belongs to the thiolase family
L2Z14_04725	COG2885	chlorophyll binding
L2Z14_04725	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z14_04735	COG1690	Belongs to the RtcB family
L2Z14_04740	COG0833	amino acid
L2Z14_04750	COG2233	PERMEase
L2Z14_04755	COG1217	gtp-binding protein TYPA
L2Z14_04780	COG2094	Belongs to the DNA glycosylase MPG family
L2Z14_04785	COG4772	TonB-dependent receptor
L2Z14_04790	COG1902	pentaerythritol trinitrate reductase activity
L2Z14_04810	COG0354	folic acid binding
L2Z14_04820	COG3189	MarR family transcriptional regulator
L2Z14_04825	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z14_04830	COG3422	double-strand break repair
L2Z14_04875	COG3328	transposase activity
L2Z14_04900	COG5510	response to toxic substance
L2Z14_04910	COG2832	Protein of unknown function (DUF454)
L2Z14_04915	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z14_04955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z14_04965	COG1289	transmembrane transporter activity
L2Z14_04970	COG2814	Major facilitator Superfamily
L2Z14_04990	COG1115	amino acid carrier protein
L2Z14_04995	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z14_05000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z14_05005	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z14_05010	COG3590	peptidase
L2Z14_05035	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z14_05045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z14_05050	COG1077	Cell shape determining protein MreB Mrl
L2Z14_05055	COG1792	Involved in formation and maintenance of cell shape
L2Z14_05060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z14_05065	COG0424	maF-like protein
L2Z14_05070	COG1530	ribonuclease E activity
L2Z14_05080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z14_05090	COG0560	Phosphoserine phosphatase
L2Z14_05100	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z14_05125	COG2207	Transcriptional regulator
L2Z14_05160	COG1113	amino acid transport
L2Z14_05165	COG2828	Protein conserved in bacteria
L2Z14_05170	COG0142	geranyltranstransferase activity
L2Z14_05175	COG2315	Protein conserved in bacteria
L2Z14_05190	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z14_05210	COG2194	sulfuric ester hydrolase activity
L2Z14_05215	COG0745	RESPONSE REGULATOR receiver
L2Z14_05220	COG0642	Histidine kinase
L2Z14_05230	COG0004	ammonium transporteR
L2Z14_05235	COG0583	DNA-binding transcription factor activity
L2Z14_05245	COG2226	methyltransferase
L2Z14_05250	COG0525	valine-tRNA ligase activity
L2Z14_05260	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_05270	COG0393	Putative heavy-metal-binding
L2Z14_05275	COG0393	Putative heavy-metal-binding
L2Z14_05280	COG1538	Outer membrane efflux protein
L2Z14_05290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z14_05295	COG0671	phosphoesterase, PA-phosphatase related
L2Z14_05325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z14_05340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z14_05340	COG1648	precorrin-2 dehydrogenase activity
L2Z14_05345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z14_05360	COG0531	amino acid
L2Z14_05375	COG0321	lipoyl(octanoyl) transferase activity
L2Z14_05380	COG2921	Belongs to the UPF0250 family
L2Z14_05415	COG2009	succinate dehydrogenase
L2Z14_05420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z14_05425	COG1053	succinate dehydrogenase
L2Z14_05430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z14_05455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z14_05475	COG2354	Protein conserved in bacteria
L2Z14_05480	COG2321	neutral zinc metallopeptidase
L2Z14_05500	COG2843	Capsule synthesis protein
L2Z14_05515	COG0589	response to stress
L2Z14_05525	COG0251	oxidation-reduction process
L2Z14_05545	COG0505	Belongs to the CarA family
L2Z14_05570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z14_05575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z14_05625	COG0477	Major facilitator Superfamily
L2Z14_05630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z14_05645	COG1597	lipid kinase activity
L2Z14_05650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z14_05675	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z14_05695	COG0741	lytic transglycosylase activity
L2Z14_05715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z14_05765	COG0210	DNA helicase
L2Z14_05780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z14_05795	COG0778	Nitroreductase
L2Z14_05810	COG1929	Belongs to the glycerate kinase type-1 family
L2Z14_05815	COG0243	molybdopterin cofactor binding
L2Z14_05820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z14_05825	COG3339	Conserved Protein
L2Z14_05835	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z14_05850	COG1115	amino acid carrier protein
L2Z14_05855	COG1113	amino acid transport
L2Z14_05865	COG0019	diaminopimelate decarboxylase activity
L2Z14_05875	COG2267	carboxylic ester hydrolase activity
L2Z14_05880	COG1280	lysine exporter protein (LysE YggA)
L2Z14_05885	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z14_05915	COG0463	Glycosyl transferase, family 2
L2Z14_05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z14_05970	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z14_05975	COG1136	(ABC) transporter
L2Z14_05980	COG0658	competence protein
L2Z14_05980	COG2333	competence protein COMEC
L2Z14_05990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z14_05990	COG0616	signal peptide processing
L2Z14_05995	COG0596	Alpha beta hydrolase
L2Z14_06000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z14_06010	COG0628	permease
L2Z14_06045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z14_06065	COG0823	Involved in the tonB-independent uptake of proteins
L2Z14_06085	COG0824	Thioesterase
L2Z14_06095	COG3328	transposase activity
L2Z14_06120	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z14_06120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z14_06125	COG2814	Major facilitator Superfamily
L2Z14_06135	COG1024	Enoyl-CoA hydratase
L2Z14_06140	COG1056	cytidyltransferase-related domain
L2Z14_06140	COG1051	belongs to the nudix hydrolase family
L2Z14_06150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z14_06165	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z14_06180	COG4625	pathogenesis
L2Z14_06185	COG0583	DNA-binding transcription factor activity
L2Z14_06190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z14_06195	COG4208	sulfate ABC transporter
L2Z14_06200	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z14_06210	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z14_06215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z14_06220	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z14_06240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z14_06255	COG0681	Belongs to the peptidase S26 family
L2Z14_06270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z14_06280	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z14_06285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z14_06295	COG4221	oxidoreductase activity
L2Z14_06325	COG0443	Heat shock 70 kDa protein
L2Z14_06340	COG0436	Aminotransferase
L2Z14_06360	COG0556	nucleotide-excision repair
L2Z14_06415	COG2070	2-Nitropropane dioxygenase
L2Z14_06445	COG3328	transposase activity
L2Z14_06455	COG1215	transferase activity, transferring glycosyl groups
L2Z14_06470	COG0415	Belongs to the DNA photolyase family
L2Z14_06480	COG1252	NADH dehydrogenase
L2Z14_06485	COG1686	Belongs to the peptidase S11 family
L2Z14_06500	COG1187	pseudouridine synthase activity
L2Z14_06525	COG0477	Major facilitator Superfamily
L2Z14_06530	COG0583	DNA-binding transcription factor activity
L2Z14_06535	COG1823	symporter activity
L2Z14_06545	COG0612	Peptidase, M16
L2Z14_06570	COG0352	thiamine-phosphate diphosphorylase activity
L2Z14_06605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z14_06620	COG1309	transcriptional regulator
L2Z14_06630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z14_06635	COG0076	glutamate decarboxylase activity
L2Z14_06645	COG1522	sequence-specific DNA binding
L2Z14_06650	COG3961	Belongs to the TPP enzyme family
L2Z14_06655	COG1113	amino acid transport
L2Z14_06660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z14_06665	COG0573	inorganic phosphate transmembrane transporter activity
L2Z14_06675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z14_06680	COG0616	signal peptide processing
L2Z14_06715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z14_06720	COG1686	Belongs to the peptidase S11 family
L2Z14_06745	COG0583	DNA-binding transcription factor activity
L2Z14_06750	COG1067	ATP-dependent peptidase activity
L2Z14_06775	COG4943	cyclic-guanylate-specific phosphodiesterase activity
L2Z14_06795	COG1966	Carbon starvation protein
L2Z14_06800	COG2879	small protein
L2Z14_06830	COG3328	transposase activity
L2Z14_06875	COG0006	proline dipeptidase activity
L2Z14_06880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z14_06885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z14_06905	COG1279	arginine transmembrane transporter activity
L2Z14_06910	COG0583	DNA-binding transcription factor activity
L2Z14_06950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z14_06955	COG0741	lytic transglycosylase activity
L2Z14_06955	COG1388	LysM domain
L2Z14_06965	COG4174	ABC transporter (Permease)
L2Z14_06970	COG4239	(ABC) transporter, permease
L2Z14_06975	COG4172	Belongs to the ABC transporter superfamily
L2Z14_06995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z14_07005	COG3706	GGDEF domain
L2Z14_07005	COG4251	negative regulation of phosphorylation
L2Z14_07005	COG5001	Diguanylate cyclase
L2Z14_07005	COG2203	Gaf domain
L2Z14_07015	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z14_07015	COG1902	pentaerythritol trinitrate reductase activity
L2Z14_07030	COG0251	oxidation-reduction process
L2Z14_07040	COG0583	DNA-binding transcription factor activity
L2Z14_07120	COG1113	amino acid transport
L2Z14_07130	COG0531	amino acid
L2Z14_07150	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_07185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
L2Z14_07190	COG0697	spore germination
L2Z14_07215	COG1960	acyl-CoA dehydrogenase activity
L2Z14_07225	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_07230	COG1024	Enoyl-CoA hydratase
L2Z14_07235	COG2814	Major facilitator Superfamily
L2Z14_07250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z14_07265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z14_07310	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L2Z14_07315	COG2072	flavoprotein involved in K transport
L2Z14_07320	COG0300	oxidoreductase activity
L2Z14_07330	COG1309	transcriptional regulator
L2Z14_07335	COG1741	Belongs to the pirin family
L2Z14_07350	COG2072	flavoprotein involved in K transport
L2Z14_07360	COG2252	PERMEase
L2Z14_07365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z14_07370	COG3038	cytochrome b561
L2Z14_07380	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z14_07390	COG0527	aspartate kinase activity
L2Z14_07400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z14_07410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z14_07425	COG0667	Aldo Keto reductase
L2Z14_07440	COG1765	OsmC-like protein
L2Z14_07450	COG3328	transposase activity
L2Z14_07460	COG0542	response to heat
L2Z14_07495	COG2885	chlorophyll binding
L2Z14_07505	COG0625	glutathione transferase activity
L2Z14_07525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z14_07545	COG3634	alkyl hydroperoxide reductase activity
L2Z14_07555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z14_07565	COG0450	alkyl hydroperoxide reductase
L2Z14_07570	COG1643	Atp-dependent helicase
L2Z14_07585	COG2814	Major facilitator Superfamily
L2Z14_07590	COG3135	benzoate transporter
L2Z14_07595	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_07600	COG0543	2 iron, 2 sulfur cluster binding
L2Z14_07600	COG0633	Ferredoxin
L2Z14_07610	COG4638	Rieske (2fe-2S)
L2Z14_07620	COG0583	DNA-binding transcription factor activity
L2Z14_07670	COG1570	exodeoxyribonuclease VII activity
L2Z14_07705	COG1278	Cold shock
L2Z14_07740	COG2814	Major facilitator Superfamily
L2Z14_07790	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z14_07800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z14_07805	COG1137	ATPase activity
L2Z14_07840	COG4122	O-methyltransferase activity
L2Z14_07850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z14_07865	COG1522	sequence-specific DNA binding
L2Z14_07870	COG5006	permease, DMT superfamily
L2Z14_07880	COG1560	Kdo2-lipid A biosynthetic process
L2Z14_07895	COG2814	Major facilitator Superfamily
L2Z14_07915	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z14_07945	COG0583	DNA-binding transcription factor activity
L2Z14_07950	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z14_07970	COG4770	biotin carboxylase activity
L2Z14_07975	COG0038	chloride channel
L2Z14_07990	COG1309	transcriptional regulator
L2Z14_08000	COG1063	alcohol dehydrogenase
L2Z14_08015	COG0439	Biotin carboxylase
L2Z14_08020	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z14_08025	COG1733	regulation of RNA biosynthetic process
L2Z14_08040	COG0864	Transcriptional regulator
L2Z14_08050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z14_08055	COG1116	anion transmembrane transporter activity
L2Z14_08135	COG0590	tRNA wobble adenosine to inosine editing
L2Z14_08140	COG2807	transmembrane transport
L2Z14_08155	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z14_08170	COG0789	Transcriptional regulator
L2Z14_08180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z14_08225	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_08230	COG0531	amino acid
L2Z14_08235	COG1760	l-serine dehydratase
L2Z14_08240	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_08240	COG2030	dehydratase
L2Z14_08245	COG3396	Phenylacetate-CoA oxygenase
L2Z14_08250	COG3460	Phenylacetate-CoA oxygenase
L2Z14_08255	COG3396	Phenylacetate-CoA oxygenase
L2Z14_08260	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z14_08265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z14_08270	COG1024	Enoyl-CoA hydratase
L2Z14_08275	COG1024	Enoyl-CoA hydratase
L2Z14_08280	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z14_08285	COG0183	Belongs to the thiolase family
L2Z14_08290	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z14_08295	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z14_08305	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z14_08320	COG3328	transposase activity
L2Z14_08340	COG0753	catalase activity
L2Z14_08345	COG3038	cytochrome b561
L2Z14_08350	COG0583	DNA-binding transcription factor activity
L2Z14_08360	COG1414	Transcriptional regulator
L2Z14_08365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z14_08380	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z14_08385	COG3842	ATPase activity
L2Z14_08400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z14_08405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z14_08410	COG2814	Major facilitator Superfamily
L2Z14_08415	COG1960	acyl-CoA dehydrogenase activity
L2Z14_08430	COG1024	Enoyl-CoA hydratase
L2Z14_08440	COG2814	Major facilitator Superfamily
L2Z14_08450	COG0183	Belongs to the thiolase family
L2Z14_08455	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z14_08460	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_08465	COG1024	Enoyl-CoA hydratase
L2Z14_08470	COG1960	acyl-CoA dehydrogenase activity
L2Z14_08475	COG2814	Major facilitator Superfamily
L2Z14_08480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z14_08485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z14_08495	COG2814	Major facilitator Superfamily
L2Z14_08505	COG1960	acyl-CoA dehydrogenase activity
L2Z14_08520	COG0583	DNA-binding transcription factor activity
L2Z14_08530	COG4770	biotin carboxylase activity
L2Z14_08535	COG1024	Enoyl-CoA hydratase
L2Z14_08540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z14_08545	COG1960	acyl-CoA dehydrogenase activity
L2Z14_08550	COG1309	transcriptional regulator
L2Z14_08555	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z14_08575	COG0583	DNA-binding transcription factor activity
L2Z14_08605	COG0732	type I restriction modification DNA specificity domain
L2Z14_08610	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
L2Z14_08635	COG4584	PFAM Integrase catalytic
L2Z14_08640	COG1484	DNA-dependent DNA replication
L2Z14_08680	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_08705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z14_08725	COG2205	protein histidine kinase activity
L2Z14_08725	COG0784	Response regulator, receiver
L2Z14_08745	COG0765	amino acid transport
L2Z14_08750	COG0765	amino acid transport
L2Z14_08755	COG1126	abc transporter atp-binding protein
L2Z14_08760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z14_08765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z14_08775	COG1280	lysine exporter protein (LysE YggA)
L2Z14_08780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z14_08785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z14_08790	COG1045	serine acetyltransferase
L2Z14_08800	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_08805	COG0583	DNA-binding transcription factor activity
L2Z14_08810	COG0625	glutathione transferase activity
L2Z14_08815	COG0625	glutathione transferase activity
L2Z14_08820	COG0583	DNA-binding transcription factor activity
L2Z14_08830	COG1346	cytolysis
L2Z14_08835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z14_08865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z14_08875	COG1294	oxidase, subunit
L2Z14_08880	COG1271	oxidase subunit
L2Z14_08900	COG0477	Major facilitator Superfamily
L2Z14_08910	COG4521	taurine ABC transporter
L2Z14_08915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z14_08920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z14_08925	COG2175	clavaminate synthase activity
L2Z14_08935	COG1953	Uracil, thiamine, allantoin
L2Z14_08970	COG0640	Transcriptional regulator
L2Z14_08975	COG0798	PFAM Bile acid sodium symporter
L2Z14_08980	COG0583	DNA-binding transcription factor activity
L2Z14_08995	COG3634	alkyl hydroperoxide reductase activity
L2Z14_09030	COG1301	dicarboxylic acid transport
L2Z14_09035	COG0436	Aminotransferase
L2Z14_09045	COG0386	Belongs to the glutathione peroxidase family
L2Z14_09085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z14_09110	COG0012	GTP binding
L2Z14_09115	COG2011	ABC-type metal ion transport system permease component
L2Z14_09120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z14_09130	COG1464	Belongs to the NlpA lipoprotein family
L2Z14_09160	COG0765	amino acid transport
L2Z14_09165	COG0765	amino acid transport
L2Z14_09170	COG1126	abc transporter atp-binding protein
L2Z14_09180	COG1522	sequence-specific DNA binding
L2Z14_09215	COG0583	DNA-binding transcription factor activity
L2Z14_09225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z14_09235	COG0697	spore germination
L2Z14_09255	COG3121	Chaperone
L2Z14_09260	COG3539	Fimbrial protein
L2Z14_09285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z14_09285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z14_09330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z14_09340	COG2353	YceI-like domain
L2Z14_09350	COG3698	Phosphodiester glycosidase
L2Z14_09365	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z14_09370	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z14_09370	COG0506	proline dehydrogenase activity
L2Z14_09370	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z14_09380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z14_09385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z14_09405	COG1132	(ABC) transporter
L2Z14_09410	COG3328	transposase activity
L2Z14_09415	COG3122	Protein conserved in bacteria
L2Z14_09420	COG3619	membrane
L2Z14_09430	COG0640	Transcriptional regulator
L2Z14_09440	COG2850	peptidyl-arginine hydroxylation
L2Z14_09445	COG0424	maF-like protein
L2Z14_09465	COG0191	fructose-bisphosphate aldolase activity
L2Z14_09470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z14_09485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z14_09495	COG1192	Involved in chromosome partitioning
L2Z14_09500	COG1475	DNA binding
L2Z14_09505	COG0811	peptide transport
L2Z14_09515	COG1132	(ABC) transporter
L2Z14_09520	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z14_09540	COG0084	hydrolase, TatD family'
L2Z14_09605	COG0776	regulation of translation
L2Z14_09635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z14_09640	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z14_09680	COG4166	transmembrane transport
L2Z14_09685	COG0339	signal peptide processing
L2Z14_09690	COG0601	transmembrane transport
L2Z14_09730	COG0702	epimerase
L2Z14_09735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z14_09755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z14_09785	COG0316	Belongs to the HesB IscA family
L2Z14_09790	COG0822	iron-sulfur transferase activity
L2Z14_09815	COG0776	regulation of translation
L2Z14_09820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z14_09825	COG2207	Transcriptional regulator
L2Z14_09830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z14_09835	COG1960	acyl-CoA dehydrogenase activity
L2Z14_09840	COG1960	acyl-CoA dehydrogenase activity
L2Z14_09855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z14_09870	COG2814	Major facilitator Superfamily
L2Z14_09875	COG4264	IucA IucC family
L2Z14_09880	COG4264	IucA IucC family
L2Z14_09890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z14_09920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z14_09935	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z14_09940	COG0406	alpha-ribazole phosphatase activity
L2Z14_09955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z14_09960	COG0730	response to heat
L2Z14_09980	COG4773	Receptor
L2Z14_09985	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z14_10005	COG0842	Transport permease protein
L2Z14_10010	COG0842	Transport permease protein
L2Z14_10035	COG0537	adenosine 5'-monophosphoramidase activity
L2Z14_10065	COG2226	methyltransferase
L2Z14_10090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z14_10125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z14_10135	COG0133	tryptophan synthase activity
L2Z14_10150	COG3706	GGDEF domain
L2Z14_10165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z14_10170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z14_10175	COG0022	dehydrogenase e1 component
L2Z14_10180	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z14_10185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z14_10195	COG1063	alcohol dehydrogenase
L2Z14_10200	COG3781	membrane
L2Z14_10205	COG3328	transposase activity
L2Z14_10215	COG3453	Protein conserved in bacteria
L2Z14_10215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z14_10230	COG0730	response to heat
L2Z14_10245	COG2207	Transcriptional regulator
L2Z14_10245	COG3708	Transcriptional regulator
L2Z14_10250	COG1733	regulation of RNA biosynthetic process
L2Z14_10255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z14_10265	COG2188	Transcriptional regulator
L2Z14_10280	COG4521	taurine ABC transporter
L2Z14_10285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z14_10305	COG0477	Major facilitator Superfamily
L2Z14_10315	COG1027	Aspartate ammonia-lyase
L2Z14_10330	COG0583	DNA-binding transcription factor activity
L2Z14_10335	COG0583	DNA-binding transcription factor activity
L2Z14_10340	COG0183	Belongs to the thiolase family
L2Z14_10345	COG2031	fatty acid transporter
L2Z14_10360	COG0583	DNA-binding transcription factor activity
L2Z14_10375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z14_10400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z14_10415	COG0543	2 iron, 2 sulfur cluster binding
L2Z14_10415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z14_10420	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z14_10425	COG4638	Rieske (2fe-2S)
L2Z14_10435	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z14_10440	COG4149	molybdate abc transporter
L2Z14_10445	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z14_10450	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_10455	COG3433	isochorismatase activity
L2Z14_10455	COG1535	isochorismatase
L2Z14_10515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z14_10530	COG0753	catalase activity
L2Z14_10540	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z14_10580	COG2072	flavoprotein involved in K transport
L2Z14_10630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z14_10675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z14_10695	COG1120	ATPase activity
L2Z14_10700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z14_10710	COG1064	alcohol dehydrogenase
L2Z14_10715	COG2207	Transcriptional regulator
L2Z14_10720	COG2084	Dehydrogenase
L2Z14_10730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z14_10735	COG0583	DNA-binding transcription factor activity
L2Z14_10745	COG0129	dihydroxy-acid dehydratase activity
L2Z14_10750	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_10765	COG1566	PFAM secretion protein HlyD family protein
L2Z14_10785	COG3328	transposase activity
L2Z14_10800	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z14_10810	COG1960	acyl-CoA dehydrogenase activity
L2Z14_10820	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_10825	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_10830	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_10840	COG1309	transcriptional regulator
L2Z14_10880	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z14_10880	COG1902	pentaerythritol trinitrate reductase activity
L2Z14_10895	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_10915	COG2186	Transcriptional regulator
L2Z14_10925	COG0583	DNA-binding transcription factor activity
L2Z14_10930	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z14_10935	COG4829	muconolactone delta-isomerase
L2Z14_10945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z14_10950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z14_10955	COG0183	Belongs to the thiolase family
L2Z14_10960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z14_10970	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_10980	COG3733	amine oxidase
L2Z14_10990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z14_11000	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_11010	COG4638	Rieske (2fe-2S)
L2Z14_11030	COG0154	amidase activity
L2Z14_11040	COG2814	Major facilitator Superfamily
L2Z14_11065	COG1960	acyl-CoA dehydrogenase activity
L2Z14_11070	COG0583	DNA-binding transcription factor activity
L2Z14_11075	COG1414	Transcriptional regulator
L2Z14_11090	COG2391	methyltransferase activity
L2Z14_11100	COG4993	Dehydrogenase
L2Z14_11105	COG3659	wide pore channel activity
L2Z14_11110	COG3420	alginic acid biosynthetic process
L2Z14_11115	COG0710	3-dehydroquinate dehydratase activity
L2Z14_11120	COG3485	protocatechuate 3,4-dioxygenase
L2Z14_11125	COG3485	protocatechuate 3,4-dioxygenase
L2Z14_11130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z14_11135	COG2271	Major facilitator Superfamily
L2Z14_11140	COG0596	Alpha beta hydrolase
L2Z14_11145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z14_11150	COG0183	Belongs to the thiolase family
L2Z14_11155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z14_11160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z14_11170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z14_11175	COG2323	membrane
L2Z14_11220	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z14_11220	COG1902	pentaerythritol trinitrate reductase activity
L2Z14_11245	COG0542	response to heat
L2Z14_11250	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z14_11280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z14_11285	COG0569	domain protein
L2Z14_11290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z14_11305	COG4774	siderophore transport
L2Z14_11310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z14_11320	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z14_11335	COG1294	oxidase, subunit
L2Z14_11340	COG4890	Cyd operon protein YbgT
L2Z14_11355	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z14_11365	COG0552	protein localization to endoplasmic reticulum
L2Z14_11390	COG0517	IMP dehydrogenase activity
L2Z14_11390	COG0516	GMP reductase activity
L2Z14_11395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z14_11400	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z14_11410	COG0583	DNA-binding transcription factor activity
L2Z14_11415	COG0024	Methionine aminopeptidase
L2Z14_11445	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z14_11445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z14_11450	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z14_11455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z14_11455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z14_11455	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z14_11485	COG2135	peptidase activity
L2Z14_11490	COG0659	secondary active sulfate transmembrane transporter activity
L2Z14_11510	COG1113	amino acid transport
L2Z14_11545	COG1011	Hydrolase
L2Z14_11550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z14_11560	COG2137	regulation of response to DNA damage stimulus
L2Z14_11575	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z14_11595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z14_11610	COG0575	Belongs to the CDS family
L2Z14_11615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z14_11640	COG3852	Histidine kinase
L2Z14_11645	COG2204	response regulator
L2Z14_11700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z14_11705	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z14_11725	COG0697	spore germination
L2Z14_11730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z14_11740	COG0303	'Molybdopterin
L2Z14_11745	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z14_11745	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z14_11760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z14_11765	COG0243	molybdopterin cofactor binding
L2Z14_11775	COG0243	molybdopterin cofactor binding
L2Z14_11780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z14_11785	COG2146	nitrite reductase [NAD(P)H] activity
L2Z14_11785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z14_11795	COG0745	RESPONSE REGULATOR receiver
L2Z14_11800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z14_11800	COG1116	anion transmembrane transporter activity
L2Z14_11820	COG0511	ligase activity, forming carbon-carbon bonds
L2Z14_11835	COG2814	Major facilitator Superfamily
L2Z14_11845	COG3293	Transposase
L2Z14_11850	COG1063	alcohol dehydrogenase
L2Z14_11860	COG3179	chitinase
L2Z14_11910	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z14_12070	COG0069	glutamate synthase activity
L2Z14_12100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z14_12110	COG1454	alcohol dehydrogenase
L2Z14_12115	COG0824	Thioesterase
L2Z14_12130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z14_12155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z14_12160	COG2030	dehydratase
L2Z14_12170	COG0183	Belongs to the thiolase family
L2Z14_12180	COG0583	DNA-binding transcription factor activity
L2Z14_12185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z14_12195	COG1522	sequence-specific DNA binding
L2Z14_12200	COG3135	benzoate transporter
L2Z14_12205	COG3328	transposase activity
L2Z14_12230	COG0589	response to stress
L2Z14_12235	COG0488	(ABC) transporter
L2Z14_12255	COG4773	Receptor
L2Z14_12275	COG3328	transposase activity
L2Z14_12290	COG0668	transmembrane transport
L2Z14_12300	COG1309	transcriptional regulator
L2Z14_12320	COG1605	Chorismate mutase
L2Z14_12350	COG0308	aminopeptidase N
L2Z14_12375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z14_12380	COG1454	alcohol dehydrogenase
L2Z14_12400	COG0531	amino acid
L2Z14_12405	COG4303	Ethanolamine ammonia lyase large subunit
L2Z14_12410	COG4302	ethanolamine ammonia-lyase activity
L2Z14_12415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z14_12415	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z14_12420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z14_12430	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z14_12445	COG0697	spore germination
L2Z14_12450	COG1923	regulation of RNA biosynthetic process
L2Z14_12460	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z14_12465	COG0802	atpase or kinase
L2Z14_12485	COG1187	pseudouridine synthase activity
L2Z14_12500	COG0583	DNA-binding transcription factor activity
L2Z14_12515	COG2814	Major facilitator Superfamily
L2Z14_12520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z14_12620	COG0729	surface antigen
L2Z14_12640	COG0174	glutamine synthetase
L2Z14_12645	COG0745	RESPONSE REGULATOR receiver
L2Z14_12655	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
L2Z14_12660	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z14_12665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z14_12690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z14_12695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z14_12700	COG1960	acyl-CoA dehydrogenase activity
L2Z14_12745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z14_12755	COG3658	cytochrome
L2Z14_12760	COG1215	transferase activity, transferring glycosyl groups
L2Z14_12765	COG0726	polysaccharide deacetylase
L2Z14_12765	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z14_12790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z14_12795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z14_12805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z14_12830	COG0305	Participates in initiation and elongation during chromosome replication
L2Z14_12835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z14_12845	COG1305	Transglutaminase-like
L2Z14_12855	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z14_12885	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z14_12890	COG0138	bifunctional purine biosynthesis protein purh
L2Z14_12895	COG0151	Belongs to the GarS family
L2Z14_12900	COG1464	Belongs to the NlpA lipoprotein family
L2Z14_12905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z14_12910	COG2011	ABC-type metal ion transport system permease component
L2Z14_12915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z14_12925	COG1301	dicarboxylic acid transport
L2Z14_12955	COG1794	racemase activity, acting on amino acids and derivatives
L2Z14_12975	COG0745	RESPONSE REGULATOR receiver
L2Z14_12980	COG0642	Histidine kinase
L2Z14_12985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2Z14_12995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2Z14_13035	COG2351	hydroxyisourate hydrolase activity
L2Z14_13045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z14_13045	COG3008	intermembrane lipid transfer
L2Z14_13050	COG2995	paraquat-inducible protein a
L2Z14_13070	COG2186	Transcriptional regulator
L2Z14_13080	COG0786	glutamate:sodium symporter activity
L2Z14_13085	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z14_13110	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z14_13210	COG1610	YqeY-like protein
L2Z14_13215	COG4783	chaperone-mediated protein folding
L2Z14_13240	COG1286	toxin biosynthetic process
L2Z14_13270	COG0778	Nitroreductase
L2Z14_13280	COG0513	Belongs to the DEAD box helicase family
L2Z14_13305	COG2363	Small membrane protein
L2Z14_13335	COG4650	regulator
L2Z14_13340	COG1234	tRNA 3'-trailer cleavage
L2Z14_13345	COG1690	Belongs to the RtcB family
L2Z14_13365	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z14_13375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z14_13390	COG1960	acyl-CoA dehydrogenase activity
L2Z14_13395	COG1301	dicarboxylic acid transport
L2Z14_13400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z14_13405	COG3139	Protein of unknown function (DUF1315)
L2Z14_13410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z14_13415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z14_13425	COG0494	nUDIX hydrolase
L2Z14_13435	COG0642	Histidine kinase
L2Z14_13450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z14_13460	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z14_13470	COG0384	phenazine biosynthesis protein PhzF
L2Z14_13475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z14_13480	COG0826	peptidase U32
L2Z14_13485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z14_13495	COG4598	ABC transporter
L2Z14_13500	COG4160	amino acid transport
L2Z14_13505	COG4215	(ABC) transporter
L2Z14_13520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z14_13565	COG1131	(ABC) transporter
L2Z14_13570	COG0842	Transport permease protein
L2Z14_13585	COG0772	Belongs to the SEDS family
L2Z14_13590	COG2951	lytic endotransglycosylase activity
L2Z14_13615	COG2207	Transcriptional regulator
L2Z14_13630	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z14_13635	COG0024	Methionine aminopeptidase
L2Z14_13645	COG3328	transposase activity
L2Z14_13650	COG2223	nitrite transmembrane transporter activity
L2Z14_13660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z14_13665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z14_13670	COG1960	acyl-CoA dehydrogenase activity
L2Z14_13685	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z14_13690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z14_13695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z14_13715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z14_13720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z14_13725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z14_13760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z14_13770	COG0174	glutamine synthetase
L2Z14_13785	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z14_13790	COG0308	aminopeptidase N
L2Z14_13820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z14_13830	COG0302	gtp cyclohydrolase
L2Z14_13850	COG3739	integral membrane protein
L2Z14_13865	COG1169	isochorismate synthase
L2Z14_13875	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z14_13880	COG1132	(ABC) transporter
L2Z14_13885	COG1132	(ABC) transporter
L2Z14_13895	COG3433	isochorismatase activity
L2Z14_13895	COG1535	isochorismatase
L2Z14_13900	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z14_13905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z14_13915	COG4774	siderophore transport
L2Z14_13920	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z14_13925	COG4604	ABC transporter, ATP-binding protein
L2Z14_13930	COG4605	iron ion homeostasis
L2Z14_13935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z14_13940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z14_13955	COG2964	Protein conserved in bacteria
L2Z14_13965	COG1741	Belongs to the pirin family
L2Z14_14110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z14_14130	COG3384	dioxygenase
L2Z14_14140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z14_14145	COG2878	Part of a membrane complex involved in electron transport
L2Z14_14150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z14_14175	COG0768	penicillin binding
L2Z14_14180	COG0742	ribosomal rna small subunit methyltransferase
L2Z14_14195	COG0830	nickel cation binding
L2Z14_14205	COG0804	urea catabolic process
L2Z14_14250	COG1253	flavin adenine dinucleotide binding
L2Z14_14255	COG2851	Citrate transporter
L2Z14_14305	COG1773	rubredoxin
L2Z14_14310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z14_14320	COG0583	DNA-binding transcription factor activity
L2Z14_14350	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z14_14355	COG4181	ATPase activity
L2Z14_14400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z14_14420	COG0306	phosphate transporter
L2Z14_14445	COG2223	nitrite transmembrane transporter activity
L2Z14_14450	COG2207	Transcriptional regulator
L2Z14_14455	COG2066	Belongs to the glutaminase family
L2Z14_14460	COG0242	peptide deformylase activity
L2Z14_14465	COG0477	Major facilitator Superfamily
L2Z14_14475	COG0028	Belongs to the TPP enzyme family
L2Z14_14490	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_14495	COG2267	carboxylic ester hydrolase activity
L2Z14_14505	COG2271	Major facilitator Superfamily
L2Z14_14520	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z14_14540	COG1414	Transcriptional regulator
L2Z14_14555	COG1024	Enoyl-CoA hydratase
L2Z14_14565	COG1215	transferase activity, transferring glycosyl groups
L2Z14_14570	COG0726	polysaccharide deacetylase
L2Z14_14570	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z14_14580	COG4681	YaeQ
L2Z14_14590	COG0523	cobalamin synthesis protein
L2Z14_14600	COG1607	acyl-coa hydrolase
L2Z14_14610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z14_14615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z14_14620	COG1309	transcriptional regulator
L2Z14_14645	COG2040	homocysteine
L2Z14_14650	COG0531	amino acid
L2Z14_14705	COG1595	DNA-templated transcription, initiation
L2Z14_14715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z14_14720	COG0477	Major facilitator Superfamily
L2Z14_14740	COG0367	asparagine synthase
L2Z14_14760	COG0156	8-amino-7-oxononanoate synthase activity
L2Z14_14765	COG2814	Major facilitator Superfamily
L2Z14_14770	COG1733	regulation of RNA biosynthetic process
L2Z14_14780	COG0582	viral genome integration into host DNA
L2Z14_14790	COG0405	Gamma-glutamyltransferase
L2Z14_14795	COG2814	Major facilitator Superfamily
L2Z14_14805	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z14_14820	COG1090	epimerase
L2Z14_14840	COG0420	3'-5' exonuclease activity
L2Z14_14865	COG0735	belongs to the Fur family
L2Z14_14870	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z14_14890	COG0121	glutamine amidotransferase
L2Z14_14905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z14_14920	COG2885	chlorophyll binding
L2Z14_14925	COG0204	Acyl-transferase
L2Z14_14940	COG2894	cell division
L2Z14_14955	COG1280	lysine exporter protein (LysE YggA)
L2Z14_14960	COG1674	ftsk spoiiie
L2Z14_14960	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z14_14965	COG0492	ferredoxin-NADP+ reductase activity
L2Z14_14970	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z14_14980	COG0456	acetyltransferase
L2Z14_15025	COG1981	membrane
L2Z14_15040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z14_15040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z14_15060	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_15070	COG0657	acetylesterase activity
L2Z14_15080	COG0473	3-isopropylmalate dehydrogenase activity
L2Z14_15085	COG0583	DNA-binding transcription factor activity
L2Z14_15105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z14_15130	COG0564	pseudouridine synthase activity
L2Z14_15140	COG0358	DNA primase activity
L2Z14_15155	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z14_15185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z14_15215	COG3328	transposase activity
L2Z14_15220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z14_15230	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z14_15230	COG0352	thiamine-phosphate diphosphorylase activity
L2Z14_15230	COG0351	phosphomethylpyrimidine kinase
L2Z14_15235	COG1652	LysM domain
L2Z14_15260	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z14_15265	COG3101	peptidyl-lysine hydroxylation
L2Z14_15270	COG0009	L-threonylcarbamoyladenylate synthase
L2Z14_15275	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z14_15280	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z14_15295	COG4106	trans-aconitate 2-methyltransferase activity
L2Z14_15310	COG0596	Alpha beta hydrolase
L2Z14_15310	COG2226	methyltransferase
L2Z14_15310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z14_15320	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z14_15325	COG2223	nitrite transmembrane transporter activity
L2Z14_15345	COG1196	nuclear chromosome segregation
L2Z14_15355	COG0730	response to heat
L2Z14_15370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z14_15380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z14_15425	COG0489	protein tyrosine kinase activity
L2Z14_15435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z14_15435	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z14_15465	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z14_15470	COG2081	HI0933 family
L2Z14_15480	COG0668	transmembrane transport
L2Z14_15500	COG0583	DNA-binding transcription factor activity
L2Z14_15520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z14_15525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z14_15555	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z14_15595	COG0745	RESPONSE REGULATOR receiver
L2Z14_15615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z14_15630	COG0384	phenazine biosynthesis protein PhzF
L2Z14_15650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z14_15665	COG0583	DNA-binding transcription factor activity
L2Z14_15695	COG0583	DNA-binding transcription factor activity
L2Z14_15710	COG0583	DNA-binding transcription factor activity
L2Z14_15715	COG1053	succinate dehydrogenase
L2Z14_15725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z14_15730	COG2814	Major facilitator Superfamily
L2Z14_15735	COG1960	acyl-CoA dehydrogenase activity
L2Z14_15740	COG0583	DNA-binding transcription factor activity
L2Z14_15770	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z14_15775	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z14_15780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z14_15795	COG3667	copper resistance
L2Z14_15800	COG2132	Multicopper oxidase
L2Z14_15810	COG0561	phosphatase activity
L2Z14_15815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z14_15825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L2Z14_15840	COG1214	PFAM Peptidase M22, glycoprotease
L2Z14_15865	COG3328	transposase activity
L2Z14_15875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z14_15885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z14_15890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z14_15895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z14_15955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z14_15965	COG1846	Transcriptional regulator
L2Z14_15970	COG1764	response to oxidative stress
L2Z14_16010	COG0037	tRNA processing
L2Z14_16020	COG0248	Ppx GppA phosphatase
L2Z14_16050	COG0072	phenylalanine-tRNA ligase activity
L2Z14_16095	COG1238	metal cluster binding
L2Z14_16100	COG0625	glutathione transferase activity
L2Z14_16115	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z14_16120	COG3028	Belongs to the UPF0307 family
L2Z14_16125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z14_16145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z14_16150	COG0617	tRNA 3'-terminal CCA addition
L2Z14_16155	COG1555	photosystem II stabilization
L2Z14_16160	COG3956	TIGRFAM MazG family protein
L2Z14_16170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z14_16190	COG2205	protein histidine kinase activity
L2Z14_16190	COG5002	protein histidine kinase activity
L2Z14_16190	COG0784	Response regulator, receiver
L2Z14_16195	COG1024	Enoyl-CoA hydratase
L2Z14_16200	COG2084	Dehydrogenase
L2Z14_16205	COG3622	Belongs to the hyi family
L2Z14_16235	COG0697	spore germination
L2Z14_16245	COG2814	Major facilitator Superfamily
L2Z14_16250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z14_16260	COG0583	DNA-binding transcription factor activity
L2Z14_16270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z14_16280	COG0084	hydrolase, TatD family'
L2Z14_16295	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z14_16320	COG2130	NADP-dependent
L2Z14_16325	COG1309	transcriptional regulator
L2Z14_16335	COG1902	pentaerythritol trinitrate reductase activity
L2Z14_16345	COG1979	alcohol dehydrogenase
L2Z14_16360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L2Z14_16375	COG0604	alcohol dehydrogenase
L2Z14_16375	COG3321	synthase
L2Z14_16380	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z14_16385	COG0583	DNA-binding transcription factor activity
L2Z14_16390	COG4221	oxidoreductase activity
L2Z14_16450	COG0440	acetolactate synthase activity
L2Z14_16455	COG0028	Belongs to the TPP enzyme family
L2Z14_16480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z14_16485	COG1136	(ABC) transporter
L2Z14_16485	COG0577	efflux transmembrane transporter activity
L2Z14_16490	COG1538	Outer membrane efflux protein
L2Z14_16505	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z14_16510	COG1162	GTPase activity
L2Z14_16520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z14_16560	COG1426	Protein conserved in bacteria
L2Z14_16595	COG0793	Belongs to the peptidase S41A family
L2Z14_16610	COG2267	carboxylic ester hydrolase activity
L2Z14_16620	COG1012	belongs to the aldehyde dehydrogenase family
L2Z14_16625	COG3265	gluconokinase activity
L2Z14_16635	COG0800	Aldolase
L2Z14_16645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z14_16650	COG0280	phosphate acetyltransferase
L2Z14_16650	COG0857	belongs to the CobB CobQ family
L2Z14_16655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z14_16655	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z14_16675	COG0740	serine-type endopeptidase activity
L2Z14_16685	COG4774	siderophore transport
L2Z14_16695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z14_16705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z14_16705	COG2813	Specifically methylates the guanine in position
L2Z14_16810	COG0788	formyltetrahydrofolate deformylase activity
L2Z14_16835	COG4651	solute:proton antiporter activity
L2Z14_16835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z14_16855	COG0724	RNA recognition motif
L2Z14_16860	COG0210	DNA helicase
L2Z14_16885	COG1733	regulation of RNA biosynthetic process
L2Z14_16895	COG2900	Belongs to the SlyX family
L2Z14_16900	COG0488	(ABC) transporter
L2Z14_16905	COG1280	lysine exporter protein (LysE YggA)
L2Z14_16910	COG1560	Kdo2-lipid A biosynthetic process
L2Z14_16920	COG1301	dicarboxylic acid transport
L2Z14_16975	COG0473	3-isopropylmalate dehydrogenase activity
L2Z14_17040	COG0583	DNA-binding transcription factor activity
L2Z14_17050	COG0625	glutathione transferase activity
L2Z14_17055	COG2378	regulation of single-species biofilm formation
L2Z14_17060	COG0546	phosphoglycolate phosphatase activity
L2Z14_17070	COG1530	ribonuclease E activity
L2Z14_17075	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z14_17090	COG0583	DNA-binding transcription factor activity
L2Z14_17100	COG3328	transposase activity
L2Z14_17110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z14_17120	COG0534	Mate efflux family protein
L2Z14_17135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z14_17165	COG0493	'glutamate synthase
L2Z14_17165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z14_17175	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z14_17180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z14_17195	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z14_17205	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z14_17205	COG0644	oxidoreductase
L2Z14_17215	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z14_17220	COG4535	Mg2 and Co2 transporter CorC
L2Z14_17230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z14_17250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z14_17255	COG0475	glutathione-regulated potassium exporter activity
L2Z14_17255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z14_17270	COG0484	heat shock protein binding
L2Z14_17275	COG0789	Transcriptional regulator
L2Z14_17280	COG0598	Magnesium transport protein CorA
L2Z14_17295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z14_17300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z14_17305	COG1074	ATP-dependent DNA helicase activity
L2Z14_17310	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z14_17330	COG2226	methyltransferase
L2Z14_17345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z14_17350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z14_17365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z14_17365	COG2111	Na H antiporter
L2Z14_17370	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z14_17375	COG0651	ATP synthesis coupled electron transport
L2Z14_17380	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z14_17385	COG2212	antiporter activity
L2Z14_17390	COG1320	monovalent cation:proton antiporter activity
L2Z14_17405	COG0195	Participates in both transcription termination and antitermination
L2Z14_17455	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z14_17460	COG0237	dephospho-CoA kinase activity