locus-tag	class	description
L2Z17_00030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z17_00035	COG0657	acetylesterase activity
L2Z17_00055	COG0583	DNA-binding transcription factor activity
L2Z17_00085	COG2951	lytic endotransglycosylase activity
L2Z17_00090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z17_00105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z17_00115	COG0671	phosphoesterase, PA-phosphatase related
L2Z17_00120	COG0861	Integral membrane protein TerC family
L2Z17_00130	COG0754	glutathionylspermidine amidase activity
L2Z17_00140	COG0402	S-adenosylhomocysteine deaminase activity
L2Z17_00155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z17_00160	COG1230	cation diffusion facilitator family transporter
L2Z17_00175	COG0706	membrane insertase activity
L2Z17_00200	COG0592	DNA-directed DNA polymerase activity
L2Z17_00210	COG0187	DNA topoisomerase II activity
L2Z17_00220	COG0586	Pfam SNARE associated Golgi protein
L2Z17_00225	COG0488	(ABC) transporter
L2Z17_00250	COG0596	Alpha beta hydrolase
L2Z17_00255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z17_00260	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z17_00300	COG1047	Peptidyl-prolyl cis-trans
L2Z17_00310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z17_00315	COG0196	riboflavin kinase activity
L2Z17_00325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z17_00330	COG1309	transcriptional regulator
L2Z17_00335	COG1116	anion transmembrane transporter activity
L2Z17_00340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z17_00345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z17_00350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z17_00355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z17_00375	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_00380	COG0546	phosphoglycolate phosphatase activity
L2Z17_00435	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z17_00440	COG0728	peptidoglycan biosynthetic process
L2Z17_00465	COG1596	polysaccharide export
L2Z17_00470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z17_00475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z17_00480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z17_00530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z17_00545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z17_00560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z17_00565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z17_00575	COG2186	Transcriptional regulator
L2Z17_00585	COG0277	FAD linked oxidase domain protein
L2Z17_00590	COG1448	Aminotransferase
L2Z17_00600	COG1802	Transcriptional regulator
L2Z17_00615	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z17_00645	COG3328	transposase activity
L2Z17_00660	COG0564	pseudouridine synthase activity
L2Z17_00700	COG0251	oxidation-reduction process
L2Z17_00705	COG1113	amino acid transport
L2Z17_00710	COG1113	amino acid transport
L2Z17_00730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z17_00735	COG1960	acyl-CoA dehydrogenase activity
L2Z17_00740	COG1024	Enoyl-CoA hydratase
L2Z17_00745	COG1024	Enoyl-CoA hydratase
L2Z17_00750	COG0477	Major facilitator Superfamily
L2Z17_00755	COG3916	Acyl-homoserine-lactone synthase
L2Z17_00765	COG2197	response regulator
L2Z17_00775	COG1960	acyl-CoA dehydrogenase activity
L2Z17_00780	COG3321	synthase
L2Z17_00780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z17_00780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z17_00780	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z17_00800	COG2267	carboxylic ester hydrolase activity
L2Z17_00820	COG0271	Belongs to the BolA IbaG family
L2Z17_00830	COG1192	Involved in chromosome partitioning
L2Z17_00845	COG0586	Pfam SNARE associated Golgi protein
L2Z17_00850	COG2259	Doxx family
L2Z17_00855	COG4399	Belongs to the UPF0754 family
L2Z17_00860	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z17_00860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z17_00905	COG0281	malic enzyme
L2Z17_00910	COG2837	iron assimilation
L2Z17_00915	COG1280	lysine exporter protein (LysE YggA)
L2Z17_00920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z17_00925	COG1121	(ABC) transporter
L2Z17_00990	COG0386	Belongs to the glutathione peroxidase family
L2Z17_01005	COG1309	transcriptional regulator
L2Z17_01010	COG0697	spore germination
L2Z17_01020	COG0758	DNA mediated transformation
L2Z17_01090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z17_01100	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z17_01140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z17_01150	COG0477	Major facilitator Superfamily
L2Z17_01160	COG1253	flavin adenine dinucleotide binding
L2Z17_01165	COG3012	SEC-C Motif Domain Protein
L2Z17_01170	COG2860	membrane
L2Z17_01175	COG0477	Major facilitator Superfamily
L2Z17_01185	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z17_01200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z17_01220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z17_01230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z17_01265	COG0589	response to stress
L2Z17_01270	COG0659	secondary active sulfate transmembrane transporter activity
L2Z17_01280	COG1002	Type II restriction enzyme, methylase subunits
L2Z17_01285	COG1061	Type III restriction enzyme res subunit
L2Z17_01330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z17_01375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z17_01415	COG0589	response to stress
L2Z17_01420	COG0659	secondary active sulfate transmembrane transporter activity
L2Z17_01430	COG1002	Type II restriction enzyme, methylase subunits
L2Z17_01435	COG1061	Type III restriction enzyme res subunit
L2Z17_01515	COG2814	Major facilitator Superfamily
L2Z17_01520	COG0583	DNA-binding transcription factor activity
L2Z17_01540	COG0667	Aldo Keto reductase
L2Z17_01575	COG1733	regulation of RNA biosynthetic process
L2Z17_01580	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z17_01645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z17_01660	COG2329	Antibiotic biosynthesis monooxygenase
L2Z17_01690	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z17_01720	COG0427	acetyl-CoA hydrolase
L2Z17_01745	COG0659	secondary active sulfate transmembrane transporter activity
L2Z17_01750	COG4221	oxidoreductase activity
L2Z17_01755	COG2873	o-acetylhomoserine
L2Z17_01760	COG0488	(ABC) transporter
L2Z17_01845	COG0833	amino acid
L2Z17_01890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z17_01895	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z17_01910	COG2226	methyltransferase
L2Z17_01960	COG0070	glutamate synthase
L2Z17_01960	COG0069	glutamate synthase activity
L2Z17_01960	COG0067	glutamate synthase
L2Z17_01965	COG0493	'glutamate synthase
L2Z17_01975	COG1704	LemA family
L2Z17_01980	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z17_02000	COG3307	-O-antigen
L2Z17_02025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z17_02040	COG0194	GDP metabolic process
L2Z17_02090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z17_02110	COG5380	lipid catabolic process
L2Z17_02115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z17_02140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z17_02145	COG0277	FAD linked oxidase domain protein
L2Z17_02155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z17_02160	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z17_02175	COG1289	transmembrane transporter activity
L2Z17_02185	COG0628	permease
L2Z17_02190	COG1192	Involved in chromosome partitioning
L2Z17_02220	COG0833	amino acid
L2Z17_02225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z17_02230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z17_02240	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_02285	COG0583	DNA-binding transcription factor activity
L2Z17_02330	COG0517	IMP dehydrogenase activity
L2Z17_02335	COG1983	PspC domain protein
L2Z17_02345	COG1960	acyl-CoA dehydrogenase activity
L2Z17_02365	COG0408	coproporphyrinogen oxidase activity
L2Z17_02385	COG0513	Belongs to the DEAD box helicase family
L2Z17_02395	COG1127	ABC transporter
L2Z17_02400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z17_02410	COG2854	intermembrane phospholipid transfer
L2Z17_02420	COG0598	Magnesium transport protein CorA
L2Z17_02430	COG0494	nUDIX hydrolase
L2Z17_02435	COG1040	competence protein
L2Z17_02440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z17_02460	COG1946	Acyl-CoA thioesterase
L2Z17_02465	COG1301	dicarboxylic acid transport
L2Z17_02480	COG1959	2 iron, 2 sulfur cluster binding
L2Z17_02485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z17_02485	COG1017	nitric oxide dioxygenase activity
L2Z17_02495	COG0433	COG0433 Predicted ATPase
L2Z17_02500	COG0626	cystathionine gamma-synthase activity
L2Z17_02655	COG1960	acyl-CoA dehydrogenase activity
L2Z17_02660	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z17_02690	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z17_02695	COG0339	signal peptide processing
L2Z17_02700	COG0557	exoribonuclease II activity
L2Z17_02745	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z17_02750	COG2169	Transcriptional regulator
L2Z17_02755	COG0697	spore germination
L2Z17_02760	COG1295	ribonuclease BN
L2Z17_02795	COG1702	phosphate starvation-inducible protein PhoH
L2Z17_02805	COG1196	nuclear chromosome segregation
L2Z17_02805	COG0739	heme binding
L2Z17_02805	COG0741	lytic transglycosylase activity
L2Z17_02835	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z17_02840	COG1183	phosphatidylcholine synthase activity
L2Z17_02885	COG1960	acyl-CoA dehydrogenase activity
L2Z17_02890	COG1309	transcriptional regulator
L2Z17_02905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z17_02910	COG1960	acyl-CoA dehydrogenase activity
L2Z17_02930	COG2969	positive regulation of protein catabolic process
L2Z17_02940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z17_02955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z17_02960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z17_02980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z17_02990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z17_02995	COG1408	metallophosphoesterase
L2Z17_03005	COG2199	diguanylate cyclase activity
L2Z17_03065	COG1607	acyl-coa hydrolase
L2Z17_03095	COG2350	Protein conserved in bacteria
L2Z17_03105	COG0613	PHP domain protein
L2Z17_03110	COG3781	membrane
L2Z17_03120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z17_03125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z17_03135	COG1862	Preprotein translocase
L2Z17_03165	COG2205	protein histidine kinase activity
L2Z17_03170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z17_03190	COG0726	polysaccharide deacetylase
L2Z17_03195	COG0463	Glycosyl transferase, family 2
L2Z17_03200	COG0438	transferase activity, transferring glycosyl groups
L2Z17_03265	COG0625	glutathione transferase activity
L2Z17_03270	COG0583	DNA-binding transcription factor activity
L2Z17_03275	COG1960	acyl-CoA dehydrogenase activity
L2Z17_03280	COG1960	acyl-CoA dehydrogenase activity
L2Z17_03290	COG2205	protein histidine kinase activity
L2Z17_03295	COG0745	RESPONSE REGULATOR receiver
L2Z17_03300	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z17_03320	COG2096	Adenosyltransferase
L2Z17_03370	COG0285	dihydrofolate synthase activity
L2Z17_03390	COG0450	alkyl hydroperoxide reductase
L2Z17_03405	COG0477	Major facilitator Superfamily
L2Z17_03410	COG1272	protein, Hemolysin III
L2Z17_03440	COG0183	Belongs to the thiolase family
L2Z17_03445	COG2207	Transcriptional regulator
L2Z17_03465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z17_03485	COG0183	Belongs to the thiolase family
L2Z17_03495	COG2885	chlorophyll binding
L2Z17_03495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z17_03505	COG1690	Belongs to the RtcB family
L2Z17_03510	COG0833	amino acid
L2Z17_03520	COG2233	PERMEase
L2Z17_03525	COG1217	gtp-binding protein TYPA
L2Z17_03550	COG2094	Belongs to the DNA glycosylase MPG family
L2Z17_03570	COG1902	pentaerythritol trinitrate reductase activity
L2Z17_03585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z17_03590	COG0354	folic acid binding
L2Z17_03600	COG3189	MarR family transcriptional regulator
L2Z17_03605	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z17_03610	COG3422	double-strand break repair
L2Z17_03650	COG0840	transmembrane signaling receptor activity
L2Z17_03670	COG5510	response to toxic substance
L2Z17_03680	COG2832	Protein of unknown function (DUF454)
L2Z17_03685	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z17_03725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z17_03735	COG1289	transmembrane transporter activity
L2Z17_03740	COG2814	Major facilitator Superfamily
L2Z17_03760	COG1115	amino acid carrier protein
L2Z17_03765	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z17_03770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z17_03775	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z17_03805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z17_03815	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z17_03820	COG1077	Cell shape determining protein MreB Mrl
L2Z17_03825	COG1792	Involved in formation and maintenance of cell shape
L2Z17_03830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z17_03835	COG0424	maF-like protein
L2Z17_03840	COG1530	ribonuclease E activity
L2Z17_03850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z17_03860	COG0560	Phosphoserine phosphatase
L2Z17_03870	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z17_03895	COG2207	Transcriptional regulator
L2Z17_03915	COG1113	amino acid transport
L2Z17_03920	COG2828	Protein conserved in bacteria
L2Z17_03925	COG0142	geranyltranstransferase activity
L2Z17_03930	COG2315	Protein conserved in bacteria
L2Z17_03945	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z17_03965	COG2194	sulfuric ester hydrolase activity
L2Z17_03970	COG0745	RESPONSE REGULATOR receiver
L2Z17_03975	COG0642	Histidine kinase
L2Z17_03985	COG0004	ammonium transporteR
L2Z17_03990	COG0583	DNA-binding transcription factor activity
L2Z17_04010	COG0525	valine-tRNA ligase activity
L2Z17_04020	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_04030	COG0393	Putative heavy-metal-binding
L2Z17_04035	COG0393	Putative heavy-metal-binding
L2Z17_04040	COG1538	Outer membrane efflux protein
L2Z17_04050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z17_04055	COG0671	phosphoesterase, PA-phosphatase related
L2Z17_04085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z17_04100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z17_04100	COG1648	precorrin-2 dehydrogenase activity
L2Z17_04105	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z17_04110	COG1733	regulation of RNA biosynthetic process
L2Z17_04120	COG0531	amino acid
L2Z17_04135	COG0321	lipoyl(octanoyl) transferase activity
L2Z17_04140	COG2921	Belongs to the UPF0250 family
L2Z17_04180	COG2009	succinate dehydrogenase
L2Z17_04185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z17_04190	COG1053	succinate dehydrogenase
L2Z17_04195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z17_04220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z17_04240	COG2354	Protein conserved in bacteria
L2Z17_04245	COG2321	neutral zinc metallopeptidase
L2Z17_04265	COG2843	Capsule synthesis protein
L2Z17_04280	COG0589	response to stress
L2Z17_04300	COG0505	Belongs to the CarA family
L2Z17_04325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z17_04330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z17_04380	COG0477	Major facilitator Superfamily
L2Z17_04385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z17_04400	COG1597	lipid kinase activity
L2Z17_04405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z17_04435	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z17_04455	COG0741	lytic transglycosylase activity
L2Z17_04475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z17_04490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z17_04510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z17_04535	COG2390	Transcriptional regulator
L2Z17_04535	COG4584	PFAM Integrase catalytic
L2Z17_04540	COG1484	DNA-dependent DNA replication
L2Z17_04565	COG0778	Nitroreductase
L2Z17_04580	COG1929	Belongs to the glycerate kinase type-1 family
L2Z17_04585	COG0243	molybdopterin cofactor binding
L2Z17_04590	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z17_04595	COG3339	Conserved Protein
L2Z17_04605	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z17_04620	COG1113	amino acid transport
L2Z17_04630	COG0019	diaminopimelate decarboxylase activity
L2Z17_04640	COG1280	lysine exporter protein (LysE YggA)
L2Z17_04645	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z17_04675	COG0463	Glycosyl transferase, family 2
L2Z17_04695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z17_04730	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z17_04735	COG1136	(ABC) transporter
L2Z17_04740	COG2333	competence protein COMEC
L2Z17_04740	COG0658	competence protein
L2Z17_04750	COG0616	signal peptide processing
L2Z17_04750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z17_04755	COG0596	Alpha beta hydrolase
L2Z17_04760	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z17_04770	COG0628	permease
L2Z17_04805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z17_04825	COG0823	Involved in the tonB-independent uptake of proteins
L2Z17_04845	COG0824	Thioesterase
L2Z17_04850	COG1473	amidohydrolase
L2Z17_04870	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z17_04870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z17_04875	COG2814	Major facilitator Superfamily
L2Z17_04885	COG1024	Enoyl-CoA hydratase
L2Z17_04890	COG1056	cytidyltransferase-related domain
L2Z17_04890	COG1051	belongs to the nudix hydrolase family
L2Z17_04900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z17_04915	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z17_04930	COG4625	pathogenesis
L2Z17_04935	COG0583	DNA-binding transcription factor activity
L2Z17_04940	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z17_04945	COG4208	sulfate ABC transporter
L2Z17_04950	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z17_04960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z17_04965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z17_04970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z17_04990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z17_05005	COG0681	Belongs to the peptidase S26 family
L2Z17_05020	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z17_05030	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z17_05035	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z17_05045	COG4221	oxidoreductase activity
L2Z17_05075	COG0436	Aminotransferase
L2Z17_05095	COG0556	nucleotide-excision repair
L2Z17_05150	COG2070	2-Nitropropane dioxygenase
L2Z17_05180	COG1215	transferase activity, transferring glycosyl groups
L2Z17_05195	COG0415	Belongs to the DNA photolyase family
L2Z17_05205	COG1252	NADH dehydrogenase
L2Z17_05210	COG1686	Belongs to the peptidase S11 family
L2Z17_05225	COG1187	pseudouridine synthase activity
L2Z17_05250	COG0477	Major facilitator Superfamily
L2Z17_05255	COG0583	DNA-binding transcription factor activity
L2Z17_05260	COG1823	symporter activity
L2Z17_05270	COG0612	Peptidase, M16
L2Z17_05295	COG0352	thiamine-phosphate diphosphorylase activity
L2Z17_05330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z17_05345	COG1309	transcriptional regulator
L2Z17_05355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z17_05360	COG0076	glutamate decarboxylase activity
L2Z17_05370	COG1522	sequence-specific DNA binding
L2Z17_05375	COG3961	Belongs to the TPP enzyme family
L2Z17_05380	COG1113	amino acid transport
L2Z17_05385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z17_05390	COG0573	inorganic phosphate transmembrane transporter activity
L2Z17_05400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z17_05405	COG0616	signal peptide processing
L2Z17_05440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z17_05445	COG1686	Belongs to the peptidase S11 family
L2Z17_05470	COG0583	DNA-binding transcription factor activity
L2Z17_05475	COG1067	ATP-dependent peptidase activity
L2Z17_05520	COG1966	Carbon starvation protein
L2Z17_05525	COG2879	small protein
L2Z17_05560	COG2508	Transcriptional regulator
L2Z17_05560	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z17_05580	COG1113	amino acid transport
L2Z17_05585	COG0583	DNA-binding transcription factor activity
L2Z17_05590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z17_05595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z17_05605	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_05615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z17_05620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z17_05620	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z17_05655	COG2814	Major facilitator Superfamily
L2Z17_05660	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z17_05670	COG1309	transcriptional regulator
L2Z17_05690	COG1741	Belongs to the pirin family
L2Z17_05700	COG2964	Protein conserved in bacteria
L2Z17_05715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z17_05720	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z17_05725	COG4605	iron ion homeostasis
L2Z17_05730	COG4604	ABC transporter, ATP-binding protein
L2Z17_05735	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z17_05740	COG4774	siderophore transport
L2Z17_05750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z17_05755	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z17_05760	COG1535	isochorismatase
L2Z17_05760	COG3433	isochorismatase activity
L2Z17_05770	COG1132	(ABC) transporter
L2Z17_05775	COG1132	(ABC) transporter
L2Z17_05780	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z17_05790	COG1169	isochorismate synthase
L2Z17_05805	COG3739	integral membrane protein
L2Z17_05830	COG0302	gtp cyclohydrolase
L2Z17_05840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z17_05870	COG0308	aminopeptidase N
L2Z17_05875	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z17_06055	COG5410	chromosome segregation
L2Z17_06210	COG0582	viral genome integration into host DNA
L2Z17_06225	COG0174	glutamine synthetase
L2Z17_06235	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z17_06270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z17_06275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z17_06280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z17_06300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z17_06305	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z17_06310	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z17_06325	COG1960	acyl-CoA dehydrogenase activity
L2Z17_06330	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z17_06335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z17_06345	COG2223	nitrite transmembrane transporter activity
L2Z17_06355	COG0024	Methionine aminopeptidase
L2Z17_06360	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z17_06375	COG2207	Transcriptional regulator
L2Z17_06400	COG2951	lytic endotransglycosylase activity
L2Z17_06405	COG0772	Belongs to the SEDS family
L2Z17_06420	COG0842	Transport permease protein
L2Z17_06425	COG1131	(ABC) transporter
L2Z17_06470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z17_06485	COG4215	(ABC) transporter
L2Z17_06490	COG4160	amino acid transport
L2Z17_06495	COG4598	ABC transporter
L2Z17_06505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z17_06510	COG0826	peptidase U32
L2Z17_06515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z17_06530	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z17_06540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z17_06555	COG0642	Histidine kinase
L2Z17_06565	COG0494	nUDIX hydrolase
L2Z17_06575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z17_06580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z17_06585	COG3139	Protein of unknown function (DUF1315)
L2Z17_06590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z17_06595	COG1301	dicarboxylic acid transport
L2Z17_06600	COG1960	acyl-CoA dehydrogenase activity
L2Z17_06605	COG2819	hydrolase of the alpha beta superfamily
L2Z17_06615	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z17_06625	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z17_06630	COG1234	tRNA 3'-trailer cleavage
L2Z17_06660	COG2363	Small membrane protein
L2Z17_06685	COG0513	Belongs to the DEAD box helicase family
L2Z17_06695	COG0778	Nitroreductase
L2Z17_06725	COG1286	toxin biosynthetic process
L2Z17_06750	COG4783	chaperone-mediated protein folding
L2Z17_06755	COG1610	YqeY-like protein
L2Z17_06855	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z17_06935	COG0300	oxidoreductase activity
L2Z17_06945	COG1309	transcriptional regulator
L2Z17_06950	COG1741	Belongs to the pirin family
L2Z17_06965	COG2072	flavoprotein involved in K transport
L2Z17_06975	COG2252	PERMEase
L2Z17_06980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z17_06985	COG3038	cytochrome b561
L2Z17_06995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z17_07005	COG0527	aspartate kinase activity
L2Z17_07015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z17_07025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z17_07040	COG0667	Aldo Keto reductase
L2Z17_07060	COG1765	OsmC-like protein
L2Z17_07075	COG0542	response to heat
L2Z17_07110	COG2885	chlorophyll binding
L2Z17_07120	COG0625	glutathione transferase activity
L2Z17_07125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z17_07145	COG3634	alkyl hydroperoxide reductase activity
L2Z17_07160	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z17_07170	COG0450	alkyl hydroperoxide reductase
L2Z17_07175	COG1643	Atp-dependent helicase
L2Z17_07190	COG2814	Major facilitator Superfamily
L2Z17_07195	COG3135	benzoate transporter
L2Z17_07200	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_07205	COG0543	2 iron, 2 sulfur cluster binding
L2Z17_07205	COG0633	Ferredoxin
L2Z17_07210	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z17_07215	COG4638	Rieske (2fe-2S)
L2Z17_07225	COG0583	DNA-binding transcription factor activity
L2Z17_07275	COG1570	exodeoxyribonuclease VII activity
L2Z17_07305	COG1280	lysine exporter protein (LysE YggA)
L2Z17_07310	COG1278	Cold shock
L2Z17_07345	COG2814	Major facilitator Superfamily
L2Z17_07380	COG0517	IMP dehydrogenase activity
L2Z17_07380	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z17_07385	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z17_07395	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z17_07400	COG1137	ATPase activity
L2Z17_07405	COG1538	Outer membrane efflux protein
L2Z17_07435	COG4122	O-methyltransferase activity
L2Z17_07445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z17_07460	COG1522	sequence-specific DNA binding
L2Z17_07465	COG5006	permease, DMT superfamily
L2Z17_07475	COG1560	Kdo2-lipid A biosynthetic process
L2Z17_07490	COG2814	Major facilitator Superfamily
L2Z17_07510	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z17_07560	COG0583	DNA-binding transcription factor activity
L2Z17_07565	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z17_07585	COG4770	biotin carboxylase activity
L2Z17_07590	COG0038	chloride channel
L2Z17_07610	COG1309	transcriptional regulator
L2Z17_07620	COG1063	alcohol dehydrogenase
L2Z17_07635	COG0439	Biotin carboxylase
L2Z17_07640	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z17_07660	COG0864	Transcriptional regulator
L2Z17_07670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z17_07675	COG1116	anion transmembrane transporter activity
L2Z17_07795	COG0590	tRNA wobble adenosine to inosine editing
L2Z17_07800	COG2807	transmembrane transport
L2Z17_07815	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z17_07830	COG0789	Transcriptional regulator
L2Z17_07840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z17_07860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z17_07870	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z17_07885	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_07890	COG0531	amino acid
L2Z17_07895	COG1760	l-serine dehydratase
L2Z17_07900	COG2030	dehydratase
L2Z17_07900	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_07905	COG3396	Phenylacetate-CoA oxygenase
L2Z17_07910	COG3460	Phenylacetate-CoA oxygenase
L2Z17_07915	COG3396	Phenylacetate-CoA oxygenase
L2Z17_07920	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z17_07925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z17_07930	COG1024	Enoyl-CoA hydratase
L2Z17_07935	COG1024	Enoyl-CoA hydratase
L2Z17_07940	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z17_07945	COG0183	Belongs to the thiolase family
L2Z17_07950	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z17_07955	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z17_07965	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z17_08000	COG0753	catalase activity
L2Z17_08005	COG3038	cytochrome b561
L2Z17_08025	COG2267	carboxylic ester hydrolase activity
L2Z17_08030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z17_08035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z17_08040	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_08050	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z17_08060	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_08065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z17_08070	COG0583	DNA-binding transcription factor activity
L2Z17_08080	COG1414	Transcriptional regulator
L2Z17_08085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z17_08095	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z17_08100	COG3842	ATPase activity
L2Z17_08115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z17_08120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z17_08125	COG2814	Major facilitator Superfamily
L2Z17_08130	COG1960	acyl-CoA dehydrogenase activity
L2Z17_08145	COG1024	Enoyl-CoA hydratase
L2Z17_08155	COG2814	Major facilitator Superfamily
L2Z17_08165	COG0183	Belongs to the thiolase family
L2Z17_08170	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z17_08175	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_08180	COG1024	Enoyl-CoA hydratase
L2Z17_08185	COG1960	acyl-CoA dehydrogenase activity
L2Z17_08190	COG2814	Major facilitator Superfamily
L2Z17_08195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z17_08200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z17_08210	COG2814	Major facilitator Superfamily
L2Z17_08220	COG1960	acyl-CoA dehydrogenase activity
L2Z17_08235	COG0583	DNA-binding transcription factor activity
L2Z17_08245	COG4770	biotin carboxylase activity
L2Z17_08250	COG1024	Enoyl-CoA hydratase
L2Z17_08255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z17_08260	COG1960	acyl-CoA dehydrogenase activity
L2Z17_08265	COG1309	transcriptional regulator
L2Z17_08270	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z17_08290	COG0583	DNA-binding transcription factor activity
L2Z17_08340	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_08360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z17_08380	COG2205	protein histidine kinase activity
L2Z17_08380	COG0784	Response regulator, receiver
L2Z17_08400	COG0765	amino acid transport
L2Z17_08405	COG0765	amino acid transport
L2Z17_08410	COG1126	abc transporter atp-binding protein
L2Z17_08415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z17_08420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z17_08435	COG1280	lysine exporter protein (LysE YggA)
L2Z17_08445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z17_08450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z17_08455	COG1045	serine acetyltransferase
L2Z17_08470	COG0583	DNA-binding transcription factor activity
L2Z17_08475	COG0625	glutathione transferase activity
L2Z17_08480	COG0625	glutathione transferase activity
L2Z17_08485	COG0583	DNA-binding transcription factor activity
L2Z17_08495	COG1346	cytolysis
L2Z17_08515	COG2814	Major facilitator Superfamily
L2Z17_08525	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z17_08530	COG3052	prosthetic group binding
L2Z17_08550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z17_08570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z17_08580	COG1294	oxidase, subunit
L2Z17_08585	COG1271	oxidase subunit
L2Z17_08605	COG0477	Major facilitator Superfamily
L2Z17_08615	COG4521	taurine ABC transporter
L2Z17_08620	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z17_08625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z17_08630	COG2175	clavaminate synthase activity
L2Z17_08640	COG1953	Uracil, thiamine, allantoin
L2Z17_08650	COG0583	DNA-binding transcription factor activity
L2Z17_08660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z17_08675	COG0640	Transcriptional regulator
L2Z17_08680	COG0798	PFAM Bile acid sodium symporter
L2Z17_08685	COG0583	DNA-binding transcription factor activity
L2Z17_08700	COG3634	alkyl hydroperoxide reductase activity
L2Z17_08740	COG0436	Aminotransferase
L2Z17_08750	COG0386	Belongs to the glutathione peroxidase family
L2Z17_08790	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z17_08815	COG0012	GTP binding
L2Z17_08820	COG2011	ABC-type metal ion transport system permease component
L2Z17_08825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z17_08835	COG1464	Belongs to the NlpA lipoprotein family
L2Z17_08865	COG0765	amino acid transport
L2Z17_08870	COG0765	amino acid transport
L2Z17_08875	COG1126	abc transporter atp-binding protein
L2Z17_08885	COG1522	sequence-specific DNA binding
L2Z17_08900	COG1309	transcriptional regulator
L2Z17_08920	COG0583	DNA-binding transcription factor activity
L2Z17_08930	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z17_08940	COG0697	spore germination
L2Z17_08965	COG3121	Chaperone
L2Z17_08970	COG3539	Fimbrial protein
L2Z17_08995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z17_08995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z17_09040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z17_09050	COG2353	YceI-like domain
L2Z17_09060	COG3698	Phosphodiester glycosidase
L2Z17_09075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z17_09080	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z17_09080	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z17_09080	COG0506	proline dehydrogenase activity
L2Z17_09090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z17_09095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z17_09115	COG1132	(ABC) transporter
L2Z17_09120	COG3122	Protein conserved in bacteria
L2Z17_09125	COG3619	membrane
L2Z17_09135	COG0640	Transcriptional regulator
L2Z17_09145	COG2850	peptidyl-arginine hydroxylation
L2Z17_09150	COG0424	maF-like protein
L2Z17_09170	COG0191	fructose-bisphosphate aldolase activity
L2Z17_09175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z17_09190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z17_09200	COG1192	Involved in chromosome partitioning
L2Z17_09205	COG1475	DNA binding
L2Z17_09210	COG0811	peptide transport
L2Z17_09220	COG1132	(ABC) transporter
L2Z17_09225	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z17_09245	COG0084	hydrolase, TatD family'
L2Z17_09310	COG0776	regulation of translation
L2Z17_09340	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z17_09400	COG0305	Participates in initiation and elongation during chromosome replication
L2Z17_09500	COG4695	Portal protein
L2Z17_09560	COG0739	heme binding
L2Z17_09560	COG1196	nuclear chromosome segregation
L2Z17_09560	COG0741	lytic transglycosylase activity
L2Z17_09630	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z17_09680	COG0339	signal peptide processing
L2Z17_09690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z17_09725	COG0702	epimerase
L2Z17_09730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z17_09750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z17_09780	COG0316	Belongs to the HesB IscA family
L2Z17_09785	COG0822	iron-sulfur transferase activity
L2Z17_09810	COG0776	regulation of translation
L2Z17_09815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z17_09820	COG2207	Transcriptional regulator
L2Z17_09825	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z17_09830	COG1960	acyl-CoA dehydrogenase activity
L2Z17_09835	COG1960	acyl-CoA dehydrogenase activity
L2Z17_09850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z17_09870	COG4264	IucA IucC family
L2Z17_09875	COG4264	IucA IucC family
L2Z17_09915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z17_09930	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z17_09950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z17_09955	COG0730	response to heat
L2Z17_09975	COG4773	Receptor
L2Z17_09980	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z17_09995	COG1131	(ABC) transporter
L2Z17_10000	COG0842	Transport permease protein
L2Z17_10005	COG0842	Transport permease protein
L2Z17_10060	COG2226	methyltransferase
L2Z17_10085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z17_10125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z17_10135	COG0133	tryptophan synthase activity
L2Z17_10150	COG3706	GGDEF domain
L2Z17_10165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z17_10170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z17_10175	COG0022	dehydrogenase e1 component
L2Z17_10180	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z17_10185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z17_10195	COG1063	alcohol dehydrogenase
L2Z17_10200	COG3781	membrane
L2Z17_10210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z17_10210	COG3453	Protein conserved in bacteria
L2Z17_10225	COG0730	response to heat
L2Z17_10240	COG2207	Transcriptional regulator
L2Z17_10240	COG3708	Transcriptional regulator
L2Z17_10245	COG1733	regulation of RNA biosynthetic process
L2Z17_10250	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z17_10260	COG2188	Transcriptional regulator
L2Z17_10275	COG4521	taurine ABC transporter
L2Z17_10280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z17_10300	COG0477	Major facilitator Superfamily
L2Z17_10310	COG1027	Aspartate ammonia-lyase
L2Z17_10325	COG0583	DNA-binding transcription factor activity
L2Z17_10330	COG0583	DNA-binding transcription factor activity
L2Z17_10335	COG0183	Belongs to the thiolase family
L2Z17_10340	COG2031	fatty acid transporter
L2Z17_10345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z17_10355	COG0583	DNA-binding transcription factor activity
L2Z17_10365	COG2610	gluconate transmembrane transporter activity
L2Z17_10370	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_10380	COG2207	Transcriptional regulator
L2Z17_10395	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_10420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z17_10420	COG0543	2 iron, 2 sulfur cluster binding
L2Z17_10425	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z17_10430	COG4638	Rieske (2fe-2S)
L2Z17_10440	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z17_10445	COG4149	molybdate abc transporter
L2Z17_10450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z17_10455	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_10460	COG3433	isochorismatase activity
L2Z17_10460	COG1535	isochorismatase
L2Z17_10520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z17_10535	COG0753	catalase activity
L2Z17_10545	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z17_10575	COG3539	Fimbrial protein
L2Z17_10595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z17_10615	COG2072	flavoprotein involved in K transport
L2Z17_10625	COG1538	Outer membrane efflux protein
L2Z17_10630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z17_10635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z17_10640	COG0745	RESPONSE REGULATOR receiver
L2Z17_10645	COG2205	protein histidine kinase activity
L2Z17_10655	COG2207	Transcriptional regulator
L2Z17_10670	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_10720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z17_10840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z17_10860	COG1120	ATPase activity
L2Z17_10865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z17_10875	COG1064	alcohol dehydrogenase
L2Z17_10890	COG2207	Transcriptional regulator
L2Z17_10895	COG2084	Dehydrogenase
L2Z17_10905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z17_10910	COG0583	DNA-binding transcription factor activity
L2Z17_10920	COG0129	dihydroxy-acid dehydratase activity
L2Z17_10925	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_10940	COG1566	PFAM secretion protein HlyD family protein
L2Z17_10975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z17_11005	COG0583	DNA-binding transcription factor activity
L2Z17_11020	COG2188	Transcriptional regulator
L2Z17_11050	COG3210	domain, Protein
L2Z17_11055	COG2831	hemolysin activation secretion protein
L2Z17_11065	COG1473	amidohydrolase
L2Z17_11075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z17_11075	COG0475	glutathione-regulated potassium exporter activity
L2Z17_11085	COG0583	DNA-binding transcription factor activity
L2Z17_11090	COG1335	isochorismatase
L2Z17_11100	COG1309	transcriptional regulator
L2Z17_11130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z17_11140	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z17_11140	COG1902	pentaerythritol trinitrate reductase activity
L2Z17_11145	COG1846	Transcriptional regulator
L2Z17_11165	COG0753	catalase activity
L2Z17_11180	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_11195	COG3162	membrane
L2Z17_11210	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_11215	COG1960	acyl-CoA dehydrogenase activity
L2Z17_11235	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_11255	COG2186	Transcriptional regulator
L2Z17_11265	COG0583	DNA-binding transcription factor activity
L2Z17_11270	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z17_11275	COG4829	muconolactone delta-isomerase
L2Z17_11285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z17_11290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z17_11295	COG0183	Belongs to the thiolase family
L2Z17_11300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z17_11310	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_11320	COG3733	amine oxidase
L2Z17_11330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z17_11340	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_11350	COG4638	Rieske (2fe-2S)
L2Z17_11370	COG0154	amidase activity
L2Z17_11380	COG2814	Major facilitator Superfamily
L2Z17_11405	COG1960	acyl-CoA dehydrogenase activity
L2Z17_11410	COG0583	DNA-binding transcription factor activity
L2Z17_11415	COG1414	Transcriptional regulator
L2Z17_11430	COG2391	methyltransferase activity
L2Z17_11440	COG4993	Dehydrogenase
L2Z17_11445	COG3659	wide pore channel activity
L2Z17_11455	COG0710	3-dehydroquinate dehydratase activity
L2Z17_11460	COG3485	protocatechuate 3,4-dioxygenase
L2Z17_11465	COG3485	protocatechuate 3,4-dioxygenase
L2Z17_11470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z17_11475	COG2271	Major facilitator Superfamily
L2Z17_11480	COG0596	Alpha beta hydrolase
L2Z17_11485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z17_11490	COG0183	Belongs to the thiolase family
L2Z17_11495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z17_11500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z17_11510	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z17_11515	COG2323	membrane
L2Z17_11560	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z17_11560	COG1902	pentaerythritol trinitrate reductase activity
L2Z17_11585	COG0542	response to heat
L2Z17_11590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z17_11620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z17_11625	COG0569	domain protein
L2Z17_11630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z17_11645	COG4774	siderophore transport
L2Z17_11650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z17_11660	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z17_11680	COG1294	oxidase, subunit
L2Z17_11685	COG4890	Cyd operon protein YbgT
L2Z17_11700	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z17_11710	COG0552	protein localization to endoplasmic reticulum
L2Z17_11735	COG0517	IMP dehydrogenase activity
L2Z17_11735	COG0516	GMP reductase activity
L2Z17_11740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z17_11745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z17_11755	COG0583	DNA-binding transcription factor activity
L2Z17_11760	COG0024	Methionine aminopeptidase
L2Z17_11790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z17_11790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z17_11795	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z17_11800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z17_11800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z17_11800	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z17_11820	COG3300	MHYT domain
L2Z17_11820	COG5001	Diguanylate cyclase
L2Z17_11835	COG2135	peptidase activity
L2Z17_11840	COG0659	secondary active sulfate transmembrane transporter activity
L2Z17_11860	COG1113	amino acid transport
L2Z17_11870	COG1522	sequence-specific DNA binding
L2Z17_11895	COG1011	Hydrolase
L2Z17_11900	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z17_11910	COG2137	regulation of response to DNA damage stimulus
L2Z17_11925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z17_11960	COG0575	Belongs to the CDS family
L2Z17_11965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z17_11985	COG3852	Histidine kinase
L2Z17_11990	COG2204	response regulator
L2Z17_12045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z17_12050	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z17_12070	COG0697	spore germination
L2Z17_12075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z17_12085	COG0303	'Molybdopterin
L2Z17_12090	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z17_12090	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z17_12105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z17_12110	COG0243	molybdopterin cofactor binding
L2Z17_12120	COG0243	molybdopterin cofactor binding
L2Z17_12125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z17_12130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z17_12130	COG2146	nitrite reductase [NAD(P)H] activity
L2Z17_12140	COG0745	RESPONSE REGULATOR receiver
L2Z17_12145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z17_12145	COG1116	anion transmembrane transporter activity
L2Z17_12165	COG0511	ligase activity, forming carbon-carbon bonds
L2Z17_12180	COG2814	Major facilitator Superfamily
L2Z17_12185	COG2194	sulfuric ester hydrolase activity
L2Z17_12250	COG0739	heme binding
L2Z17_12370	COG5410	chromosome segregation
L2Z17_12560	COG0069	glutamate synthase activity
L2Z17_12580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z17_12590	COG1454	alcohol dehydrogenase
L2Z17_12595	COG0824	Thioesterase
L2Z17_12605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z17_12620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z17_12625	COG2030	dehydratase
L2Z17_12635	COG0183	Belongs to the thiolase family
L2Z17_12645	COG0583	DNA-binding transcription factor activity
L2Z17_12650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z17_12660	COG1522	sequence-specific DNA binding
L2Z17_12665	COG3135	benzoate transporter
L2Z17_12675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z17_12700	COG0589	response to stress
L2Z17_12705	COG0488	(ABC) transporter
L2Z17_12725	COG4773	Receptor
L2Z17_12760	COG0668	transmembrane transport
L2Z17_12770	COG1309	transcriptional regulator
L2Z17_12790	COG1605	Chorismate mutase
L2Z17_12800	COG4221	oxidoreductase activity
L2Z17_12810	COG0308	aminopeptidase N
L2Z17_12830	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z17_12840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z17_12845	COG1454	alcohol dehydrogenase
L2Z17_12865	COG0531	amino acid
L2Z17_12870	COG4303	Ethanolamine ammonia lyase large subunit
L2Z17_12875	COG4302	ethanolamine ammonia-lyase activity
L2Z17_12880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z17_12880	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z17_12885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z17_12895	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z17_12910	COG0697	spore germination
L2Z17_12915	COG1923	regulation of RNA biosynthetic process
L2Z17_12925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z17_12930	COG0802	atpase or kinase
L2Z17_12950	COG1187	pseudouridine synthase activity
L2Z17_12965	COG0583	DNA-binding transcription factor activity
L2Z17_12980	COG2814	Major facilitator Superfamily
L2Z17_12985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z17_13010	COG0729	surface antigen
L2Z17_13030	COG0174	glutamine synthetase
L2Z17_13035	COG0745	RESPONSE REGULATOR receiver
L2Z17_13040	COG2205	protein histidine kinase activity
L2Z17_13050	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z17_13055	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z17_13080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z17_13085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z17_13090	COG1960	acyl-CoA dehydrogenase activity
L2Z17_13105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z17_13110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z17_13130	COG0583	DNA-binding transcription factor activity
L2Z17_13145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z17_13155	COG3658	cytochrome
L2Z17_13160	COG1215	transferase activity, transferring glycosyl groups
L2Z17_13165	COG0726	polysaccharide deacetylase
L2Z17_13165	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z17_13190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z17_13195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z17_13205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z17_13230	COG0305	Participates in initiation and elongation during chromosome replication
L2Z17_13235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z17_13245	COG1305	Transglutaminase-like
L2Z17_13255	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z17_13285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z17_13290	COG0138	bifunctional purine biosynthesis protein purh
L2Z17_13295	COG0151	Belongs to the GarS family
L2Z17_13300	COG1464	Belongs to the NlpA lipoprotein family
L2Z17_13305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z17_13310	COG2011	ABC-type metal ion transport system permease component
L2Z17_13315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z17_13325	COG1301	dicarboxylic acid transport
L2Z17_13365	COG2433	Pfam Transposase IS66
L2Z17_13375	COG3173	Aminoglycoside phosphotransferase
L2Z17_13380	COG0488	(ABC) transporter
L2Z17_13490	COG4269	membrane
L2Z17_13505	COG1902	pentaerythritol trinitrate reductase activity
L2Z17_13505	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z17_13515	COG2203	Gaf domain
L2Z17_13515	COG3706	GGDEF domain
L2Z17_13515	COG4251	negative regulation of phosphorylation
L2Z17_13515	COG5001	Diguanylate cyclase
L2Z17_13525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z17_13555	COG4172	Belongs to the ABC transporter superfamily
L2Z17_13560	COG4239	(ABC) transporter, permease
L2Z17_13565	COG4174	ABC transporter (Permease)
L2Z17_13575	COG0741	lytic transglycosylase activity
L2Z17_13575	COG1388	LysM domain
L2Z17_13575	COG0741	lytic transglycosylase activity
L2Z17_13575	COG1388	LysM domain
L2Z17_13580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z17_13620	COG0583	DNA-binding transcription factor activity
L2Z17_13625	COG1279	arginine transmembrane transporter activity
L2Z17_13645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z17_13650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z17_13655	COG0006	proline dipeptidase activity
L2Z17_13740	COG0739	heme binding
L2Z17_14065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z17_14090	COG3384	dioxygenase
L2Z17_14100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z17_14105	COG2878	Part of a membrane complex involved in electron transport
L2Z17_14110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z17_14135	COG0768	penicillin binding
L2Z17_14140	COG0742	ribosomal rna small subunit methyltransferase
L2Z17_14155	COG0830	nickel cation binding
L2Z17_14165	COG0804	urea catabolic process
L2Z17_14205	COG1253	flavin adenine dinucleotide binding
L2Z17_14210	COG2851	Citrate transporter
L2Z17_14260	COG1773	rubredoxin
L2Z17_14265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z17_14275	COG0583	DNA-binding transcription factor activity
L2Z17_14310	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z17_14315	COG4181	ATPase activity
L2Z17_14360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z17_14380	COG0306	phosphate transporter
L2Z17_14390	COG3958	Transketolase
L2Z17_14395	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z17_14400	COG2271	Major facilitator Superfamily
L2Z17_14405	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_14410	COG0583	DNA-binding transcription factor activity
L2Z17_14425	COG2223	nitrite transmembrane transporter activity
L2Z17_14430	COG2207	Transcriptional regulator
L2Z17_14435	COG2066	Belongs to the glutaminase family
L2Z17_14440	COG0242	peptide deformylase activity
L2Z17_14445	COG0477	Major facilitator Superfamily
L2Z17_14455	COG0028	Belongs to the TPP enzyme family
L2Z17_14470	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_14475	COG2267	carboxylic ester hydrolase activity
L2Z17_14485	COG2271	Major facilitator Superfamily
L2Z17_14490	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z17_14500	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_14520	COG1414	Transcriptional regulator
L2Z17_14535	COG1024	Enoyl-CoA hydratase
L2Z17_14545	COG1215	transferase activity, transferring glycosyl groups
L2Z17_14550	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z17_14550	COG0726	polysaccharide deacetylase
L2Z17_14560	COG4681	YaeQ
L2Z17_14570	COG0523	cobalamin synthesis protein
L2Z17_14580	COG1607	acyl-coa hydrolase
L2Z17_14590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z17_14595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z17_14600	COG1309	transcriptional regulator
L2Z17_14625	COG2040	homocysteine
L2Z17_14630	COG0531	amino acid
L2Z17_14685	COG1595	DNA-templated transcription, initiation
L2Z17_14695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z17_14700	COG0477	Major facilitator Superfamily
L2Z17_14720	COG0084	hydrolase, TatD family'
L2Z17_14830	COG0592	DNA-directed DNA polymerase activity
L2Z17_14870	COG2026	Addiction module toxin, RelE StbE family
L2Z17_15030	COG3755	Protein conserved in bacteria
L2Z17_15075	COG1484	DNA-dependent DNA replication
L2Z17_15165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z17_15235	COG0405	Gamma-glutamyltransferase
L2Z17_15240	COG2814	Major facilitator Superfamily
L2Z17_15250	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z17_15265	COG1090	epimerase
L2Z17_15285	COG0420	3'-5' exonuclease activity
L2Z17_15310	COG0735	belongs to the Fur family
L2Z17_15315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z17_15335	COG0121	glutamine amidotransferase
L2Z17_15350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z17_15360	COG0210	DNA helicase
L2Z17_15365	COG2885	chlorophyll binding
L2Z17_15370	COG0204	Acyl-transferase
L2Z17_15385	COG2894	cell division
L2Z17_15405	COG1280	lysine exporter protein (LysE YggA)
L2Z17_15410	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z17_15410	COG1674	ftsk spoiiie
L2Z17_15415	COG0492	ferredoxin-NADP+ reductase activity
L2Z17_15420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z17_15430	COG0456	acetyltransferase
L2Z17_15475	COG1981	membrane
L2Z17_15490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z17_15490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z17_15510	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_15520	COG0657	acetylesterase activity
L2Z17_15530	COG0473	3-isopropylmalate dehydrogenase activity
L2Z17_15535	COG0583	DNA-binding transcription factor activity
L2Z17_15555	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z17_15580	COG0564	pseudouridine synthase activity
L2Z17_15590	COG0358	DNA primase activity
L2Z17_15605	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z17_15635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z17_15665	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z17_15675	COG0351	phosphomethylpyrimidine kinase
L2Z17_15675	COG0352	thiamine-phosphate diphosphorylase activity
L2Z17_15675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z17_15680	COG1652	LysM domain
L2Z17_15705	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z17_15710	COG3101	peptidyl-lysine hydroxylation
L2Z17_15715	COG0009	L-threonylcarbamoyladenylate synthase
L2Z17_15720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z17_15725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z17_15740	COG4106	trans-aconitate 2-methyltransferase activity
L2Z17_15755	COG0596	Alpha beta hydrolase
L2Z17_15755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z17_15755	COG2226	methyltransferase
L2Z17_15760	COG1877	trehalose-phosphatase activity
L2Z17_15765	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z17_15770	COG2223	nitrite transmembrane transporter activity
L2Z17_15790	COG1196	nuclear chromosome segregation
L2Z17_15800	COG0730	response to heat
L2Z17_15815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z17_15825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z17_15875	COG0489	protein tyrosine kinase activity
L2Z17_15885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z17_15885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z17_15915	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z17_15920	COG2081	HI0933 family
L2Z17_15930	COG0668	transmembrane transport
L2Z17_15950	COG0583	DNA-binding transcription factor activity
L2Z17_15970	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z17_15975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z17_16005	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z17_16045	COG0745	RESPONSE REGULATOR receiver
L2Z17_16065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z17_16075	COG2205	protein histidine kinase activity
L2Z17_16140	COG4993	Dehydrogenase
L2Z17_16160	COG0384	phenazine biosynthesis protein PhzF
L2Z17_16185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z17_16200	COG0583	DNA-binding transcription factor activity
L2Z17_16230	COG0583	DNA-binding transcription factor activity
L2Z17_16245	COG0583	DNA-binding transcription factor activity
L2Z17_16250	COG1053	succinate dehydrogenase
L2Z17_16260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z17_16265	COG2814	Major facilitator Superfamily
L2Z17_16270	COG1960	acyl-CoA dehydrogenase activity
L2Z17_16275	COG0583	DNA-binding transcription factor activity
L2Z17_16280	COG1063	alcohol dehydrogenase
L2Z17_16310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z17_16315	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z17_16320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z17_16345	COG3667	copper resistance
L2Z17_16350	COG2132	Multicopper oxidase
L2Z17_16360	COG0561	phosphatase activity
L2Z17_16365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z17_16390	COG1214	PFAM Peptidase M22, glycoprotease
L2Z17_16440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z17_16450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z17_16455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z17_16460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z17_16520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z17_16530	COG1846	Transcriptional regulator
L2Z17_16535	COG1764	response to oxidative stress
L2Z17_16575	COG0037	tRNA processing
L2Z17_16585	COG0248	Ppx GppA phosphatase
L2Z17_16615	COG0072	phenylalanine-tRNA ligase activity
L2Z17_16660	COG1238	metal cluster binding
L2Z17_16665	COG0625	glutathione transferase activity
L2Z17_16680	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z17_16685	COG3028	Belongs to the UPF0307 family
L2Z17_16690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z17_16710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z17_16715	COG0617	tRNA 3'-terminal CCA addition
L2Z17_16720	COG1555	photosystem II stabilization
L2Z17_16725	COG3956	TIGRFAM MazG family protein
L2Z17_16735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z17_16755	COG0784	Response regulator, receiver
L2Z17_16755	COG2205	protein histidine kinase activity
L2Z17_16755	COG5002	protein histidine kinase activity
L2Z17_16760	COG1024	Enoyl-CoA hydratase
L2Z17_16765	COG2084	Dehydrogenase
L2Z17_16770	COG3622	Belongs to the hyi family
L2Z17_16800	COG0697	spore germination
L2Z17_16810	COG2814	Major facilitator Superfamily
L2Z17_16820	COG4772	TonB-dependent receptor
L2Z17_16825	COG4774	siderophore transport
L2Z17_16840	COG1271	oxidase subunit
L2Z17_16845	COG1294	oxidase, subunit
L2Z17_16915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z17_16925	COG0583	DNA-binding transcription factor activity
L2Z17_16935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z17_16950	COG0084	hydrolase, TatD family'
L2Z17_16965	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z17_16995	COG0440	acetolactate synthase activity
L2Z17_17000	COG0028	Belongs to the TPP enzyme family
L2Z17_17025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z17_17030	COG0577	efflux transmembrane transporter activity
L2Z17_17030	COG1136	(ABC) transporter
L2Z17_17035	COG1538	Outer membrane efflux protein
L2Z17_17050	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z17_17055	COG1162	GTPase activity
L2Z17_17065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z17_17085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z17_17090	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_17130	COG2986	histidine ammonia-lyase
L2Z17_17145	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z17_17155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z17_17200	COG1426	Protein conserved in bacteria
L2Z17_17235	COG0793	Belongs to the peptidase S41A family
L2Z17_17250	COG2267	carboxylic ester hydrolase activity
L2Z17_17260	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_17265	COG3265	gluconokinase activity
L2Z17_17275	COG0800	Aldolase
L2Z17_17285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z17_17290	COG0280	phosphate acetyltransferase
L2Z17_17290	COG0857	belongs to the CobB CobQ family
L2Z17_17295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z17_17295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z17_17315	COG0740	serine-type endopeptidase activity
L2Z17_17325	COG4774	siderophore transport
L2Z17_17335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z17_17345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z17_17345	COG2813	Specifically methylates the guanine in position
L2Z17_17445	COG0788	formyltetrahydrofolate deformylase activity
L2Z17_17470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z17_17470	COG4651	solute:proton antiporter activity
L2Z17_17490	COG0724	RNA recognition motif
L2Z17_17495	COG0210	DNA helicase
L2Z17_17520	COG1733	regulation of RNA biosynthetic process
L2Z17_17530	COG2900	Belongs to the SlyX family
L2Z17_17535	COG0488	(ABC) transporter
L2Z17_17540	COG1280	lysine exporter protein (LysE YggA)
L2Z17_17545	COG1560	Kdo2-lipid A biosynthetic process
L2Z17_17555	COG1301	dicarboxylic acid transport
L2Z17_17610	COG0473	3-isopropylmalate dehydrogenase activity
L2Z17_17675	COG0583	DNA-binding transcription factor activity
L2Z17_17685	COG0625	glutathione transferase activity
L2Z17_17690	COG2378	regulation of single-species biofilm formation
L2Z17_17695	COG0546	phosphoglycolate phosphatase activity
L2Z17_17705	COG1530	ribonuclease E activity
L2Z17_17710	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z17_17725	COG0583	DNA-binding transcription factor activity
L2Z17_17730	COG4221	oxidoreductase activity
L2Z17_17735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z17_17745	COG0534	Mate efflux family protein
L2Z17_17760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z17_17800	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z17_17805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z17_17820	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z17_17830	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z17_17830	COG0644	oxidoreductase
L2Z17_17835	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z17_17840	COG4535	Mg2 and Co2 transporter CorC
L2Z17_17850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z17_17870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z17_17875	COG0475	glutathione-regulated potassium exporter activity
L2Z17_17875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z17_17880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z17_17890	COG0484	heat shock protein binding
L2Z17_17895	COG0789	Transcriptional regulator
L2Z17_17900	COG0598	Magnesium transport protein CorA
L2Z17_17915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z17_17920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z17_17925	COG1074	ATP-dependent DNA helicase activity
L2Z17_17930	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z17_17950	COG2226	methyltransferase
L2Z17_17965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z17_17970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z17_17985	COG2111	Na H antiporter
L2Z17_17985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z17_17990	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z17_17995	COG0651	ATP synthesis coupled electron transport
L2Z17_18000	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z17_18005	COG2212	antiporter activity
L2Z17_18010	COG1320	monovalent cation:proton antiporter activity
L2Z17_18025	COG0195	Participates in both transcription termination and antitermination
L2Z17_18075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z17_18080	COG0237	dephospho-CoA kinase activity
L2Z17_18090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z17_18105	COG0497	DNA recombination
L2Z17_18115	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z17_18145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z17_18145	COG2169	Transcriptional regulator
L2Z17_18150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z17_18215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z17_18230	COG0326	Molecular chaperone. Has ATPase activity
L2Z17_18245	COG2056	Na+-H+ antiporter family
L2Z17_18250	COG0596	Alpha beta hydrolase
L2Z17_18345	COG0546	phosphoglycolate phosphatase activity
L2Z17_18350	COG1716	ATPase activity
L2Z17_18395	COG0181	hydroxymethylbilane synthase activity
L2Z17_18405	COG3275	phosphorelay sensor kinase activity
L2Z17_18425	COG1538	Outer membrane efflux protein
L2Z17_18430	COG0697	spore germination
L2Z17_18455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z17_18460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z17_18465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z17_18470	COG0772	Belongs to the SEDS family
L2Z17_18495	COG4974	Belongs to the 'phage' integrase family
L2Z17_18500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z17_18510	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z17_18520	COG2197	response regulator
L2Z17_18535	COG0793	Belongs to the peptidase S41A family
L2Z17_18540	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z17_18545	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z17_18585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z17_18585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z17_18595	COG0004	ammonium transporteR
L2Z17_18600	COG0347	Belongs to the P(II) protein family
L2Z17_18640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z17_18655	COG1192	Involved in chromosome partitioning
L2Z17_18815	COG0488	(ABC) transporter
L2Z17_18820	COG3173	Aminoglycoside phosphotransferase
L2Z17_18850	COG1335	isochorismatase
L2Z17_18860	COG1012	belongs to the aldehyde dehydrogenase family
L2Z17_18865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z17_18875	COG1113	amino acid transport
L2Z17_18885	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z17_18900	COG2814	Major facilitator Superfamily
L2Z17_18910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z17_18910	COG0352	thiamine-phosphate diphosphorylase activity
L2Z17_18910	COG0351	phosphomethylpyrimidine kinase
L2Z17_18930	COG1309	transcriptional regulator
L2Z17_18935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z17_18955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z17_18965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z17_18970	COG3162	membrane
L2Z17_18975	COG2205	protein histidine kinase activity
L2Z17_18975	COG0784	Response regulator, receiver
L2Z17_18975	COG2198	Histidine kinase
L2Z17_19000	COG3328	transposase activity
L2Z17_19005	COG1522	sequence-specific DNA binding
L2Z17_19010	COG1335	isochorismatase
L2Z17_19015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z17_19025	COG0668	transmembrane transport
L2Z17_19030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z17_19035	COG1519	Transferase
L2Z17_19040	COG1902	pentaerythritol trinitrate reductase activity
L2Z17_19060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z17_19085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z17_19085	COG0426	domain, Protein
L2Z17_19090	COG4774	siderophore transport
L2Z17_19095	COG2119	membrane
L2Z17_19105	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z17_19115	COG4942	peptidase
L2Z17_19130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z17_19140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z17_19160	COG0189	ligase activity
L2Z17_19180	COG0708	Exodeoxyribonuclease III
L2Z17_19185	COG1393	Belongs to the ArsC family
L2Z17_19200	COG3706	GGDEF domain
L2Z17_19235	COG2351	hydroxyisourate hydrolase activity
L2Z17_19240	COG2233	PERMEase
L2Z17_19250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z17_19260	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z17_19265	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z17_19275	COG3150	esterase
L2Z17_19330	COG2918	glutathione biosynthetic process
L2Z17_19345	COG2733	membrane
L2Z17_19350	COG0436	Aminotransferase
L2Z17_19355	COG0534	Mate efflux family protein
L2Z17_19440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z17_19445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z17_19455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z17_19510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z17_19525	COG0010	Belongs to the arginase family
L2Z17_19555	COG2188	Transcriptional regulator
L2Z17_19565	COG0523	cobalamin synthesis protein
L2Z17_19575	COG1113	amino acid transport
L2Z17_19585	COG0625	glutathione transferase activity
L2Z17_19605	COG1683	Conserved Protein
L2Z17_19610	COG0534	Mate efflux family protein
L2Z17_19615	COG0385	Bile acid
L2Z17_19620	COG1335	isochorismatase
L2Z17_19625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z17_19645	COG2116	formate transmembrane transporter activity
L2Z17_19650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z17_19655	COG2133	pyrroloquinoline quinone binding
L2Z17_19660	COG2983	Belongs to the UPF0260 family
L2Z17_19680	COG1194	a g-specific adenine glycosylase
L2Z17_19695	COG2818	Glycosylase
L2Z17_19700	COG1064	alcohol dehydrogenase
L2Z17_19705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z17_19720	COG0583	DNA-binding transcription factor activity
L2Z17_19725	COG0656	L-ascorbic acid biosynthetic process
L2Z17_19730	COG2814	Major facilitator Superfamily
L2Z17_19765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z17_19780	COG2233	PERMEase
L2Z17_19785	COG0583	DNA-binding transcription factor activity
L2Z17_19820	COG0733	neurotransmitter:sodium symporter activity