locus-tag	class	description
L2Z19_00035	COG0739	heme binding
L2Z19_00035	COG0741	lytic transglycosylase activity
L2Z19_00035	COG1196	nuclear chromosome segregation
L2Z19_00050	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z19_00140	COG5410	chromosome segregation
L2Z19_00340	COG0069	glutamate synthase activity
L2Z19_00370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z19_00380	COG1454	alcohol dehydrogenase
L2Z19_00385	COG0824	Thioesterase
L2Z19_00395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z19_00420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z19_00425	COG2030	dehydratase
L2Z19_00435	COG0183	Belongs to the thiolase family
L2Z19_00445	COG0583	DNA-binding transcription factor activity
L2Z19_00450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z19_00460	COG1522	sequence-specific DNA binding
L2Z19_00465	COG3135	benzoate transporter
L2Z19_00475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z19_00500	COG0589	response to stress
L2Z19_00505	COG0488	(ABC) transporter
L2Z19_00525	COG4773	Receptor
L2Z19_00550	COG3293	Transposase
L2Z19_00560	COG0668	transmembrane transport
L2Z19_00570	COG1309	transcriptional regulator
L2Z19_00590	COG1605	Chorismate mutase
L2Z19_00630	COG0308	aminopeptidase N
L2Z19_00655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z19_00660	COG1454	alcohol dehydrogenase
L2Z19_00680	COG0531	amino acid
L2Z19_00685	COG4303	Ethanolamine ammonia lyase large subunit
L2Z19_00690	COG4302	ethanolamine ammonia-lyase activity
L2Z19_00695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z19_00695	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z19_00700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z19_00725	COG0697	spore germination
L2Z19_00730	COG1923	regulation of RNA biosynthetic process
L2Z19_00740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z19_00745	COG0802	atpase or kinase
L2Z19_00765	COG1187	pseudouridine synthase activity
L2Z19_00780	COG0583	DNA-binding transcription factor activity
L2Z19_00795	COG2814	Major facilitator Superfamily
L2Z19_00800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z19_00825	COG0729	surface antigen
L2Z19_00845	COG0174	glutamine synthetase
L2Z19_00850	COG3293	Transposase
L2Z19_00855	COG0745	RESPONSE REGULATOR receiver
L2Z19_00860	COG2205	protein histidine kinase activity
L2Z19_00870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z19_00875	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z19_00900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z19_00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z19_00910	COG1960	acyl-CoA dehydrogenase activity
L2Z19_00955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z19_00965	COG3658	cytochrome
L2Z19_00970	COG1215	transferase activity, transferring glycosyl groups
L2Z19_00975	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z19_00975	COG0726	polysaccharide deacetylase
L2Z19_01000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z19_01005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z19_01015	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z19_01040	COG0305	Participates in initiation and elongation during chromosome replication
L2Z19_01045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z19_01055	COG1305	Transglutaminase-like
L2Z19_01065	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z19_01095	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z19_01100	COG0138	bifunctional purine biosynthesis protein purh
L2Z19_01105	COG0151	Belongs to the GarS family
L2Z19_01110	COG1464	Belongs to the NlpA lipoprotein family
L2Z19_01115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z19_01120	COG2011	ABC-type metal ion transport system permease component
L2Z19_01125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z19_01135	COG1301	dicarboxylic acid transport
L2Z19_01165	COG1794	racemase activity, acting on amino acids and derivatives
L2Z19_01185	COG0745	RESPONSE REGULATOR receiver
L2Z19_01190	COG0642	Histidine kinase
L2Z19_01195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2Z19_01205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2Z19_01245	COG2351	hydroxyisourate hydrolase activity
L2Z19_01255	COG3008	intermembrane lipid transfer
L2Z19_01255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z19_01260	COG2995	paraquat-inducible protein a
L2Z19_01275	COG2985	domain, Protein
L2Z19_01300	COG0477	Major facilitator Superfamily
L2Z19_01355	COG2186	Transcriptional regulator
L2Z19_01365	COG0786	glutamate:sodium symporter activity
L2Z19_01370	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z19_01395	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z19_01480	COG3210	domain, Protein
L2Z19_01480	COG3210	domain, Protein
L2Z19_01485	COG2831	hemolysin activation secretion protein
L2Z19_01540	COG1610	YqeY-like protein
L2Z19_01545	COG4783	chaperone-mediated protein folding
L2Z19_01570	COG1286	toxin biosynthetic process
L2Z19_01600	COG0778	Nitroreductase
L2Z19_01610	COG0513	Belongs to the DEAD box helicase family
L2Z19_01635	COG2363	Small membrane protein
L2Z19_01665	COG1234	tRNA 3'-trailer cleavage
L2Z19_01670	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z19_01680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z19_01690	COG2819	hydrolase of the alpha beta superfamily
L2Z19_01695	COG1960	acyl-CoA dehydrogenase activity
L2Z19_01700	COG1301	dicarboxylic acid transport
L2Z19_01705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z19_01710	COG3139	Protein of unknown function (DUF1315)
L2Z19_01715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z19_01720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z19_01730	COG0494	nUDIX hydrolase
L2Z19_01740	COG0642	Histidine kinase
L2Z19_01755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z19_01765	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z19_01780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z19_01785	COG0826	peptidase U32
L2Z19_01790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z19_01800	COG4598	ABC transporter
L2Z19_01805	COG4160	amino acid transport
L2Z19_01810	COG4215	(ABC) transporter
L2Z19_01825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z19_01870	COG1131	(ABC) transporter
L2Z19_01875	COG0842	Transport permease protein
L2Z19_01890	COG0772	Belongs to the SEDS family
L2Z19_01895	COG2951	lytic endotransglycosylase activity
L2Z19_01920	COG2207	Transcriptional regulator
L2Z19_01935	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z19_01940	COG0024	Methionine aminopeptidase
L2Z19_01970	COG2801	Transposase and inactivated derivatives
L2Z19_01990	COG1116	anion transmembrane transporter activity
L2Z19_01995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z19_02005	COG0864	Transcriptional regulator
L2Z19_02015	COG1733	regulation of RNA biosynthetic process
L2Z19_02020	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z19_02025	COG0439	Biotin carboxylase
L2Z19_02040	COG1063	alcohol dehydrogenase
L2Z19_02050	COG1309	transcriptional regulator
L2Z19_02070	COG0038	chloride channel
L2Z19_02075	COG4770	biotin carboxylase activity
L2Z19_02095	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z19_02100	COG0583	DNA-binding transcription factor activity
L2Z19_02150	COG1011	Hydrolase
L2Z19_02170	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z19_02190	COG2814	Major facilitator Superfamily
L2Z19_02210	COG0598	Magnesium transport protein CorA
L2Z19_02215	COG1560	Kdo2-lipid A biosynthetic process
L2Z19_02230	COG1522	sequence-specific DNA binding
L2Z19_02245	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z19_02255	COG4122	O-methyltransferase activity
L2Z19_02290	COG1137	ATPase activity
L2Z19_02295	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z19_02305	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z19_02310	COG0517	IMP dehydrogenase activity
L2Z19_02310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z19_02350	COG2814	Major facilitator Superfamily
L2Z19_02385	COG1278	Cold shock
L2Z19_02390	COG1280	lysine exporter protein (LysE YggA)
L2Z19_02420	COG1570	exodeoxyribonuclease VII activity
L2Z19_02505	COG2871	sodium ion transport
L2Z19_02515	COG0583	DNA-binding transcription factor activity
L2Z19_02525	COG4638	Rieske (2fe-2S)
L2Z19_02535	COG0543	2 iron, 2 sulfur cluster binding
L2Z19_02535	COG0633	Ferredoxin
L2Z19_02540	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_02545	COG3135	benzoate transporter
L2Z19_02550	COG2814	Major facilitator Superfamily
L2Z19_02565	COG1643	Atp-dependent helicase
L2Z19_02570	COG0450	alkyl hydroperoxide reductase
L2Z19_02580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z19_02590	COG3634	alkyl hydroperoxide reductase activity
L2Z19_02615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z19_02620	COG0625	glutathione transferase activity
L2Z19_02630	COG2885	chlorophyll binding
L2Z19_02665	COG0542	response to heat
L2Z19_02680	COG1765	OsmC-like protein
L2Z19_02695	COG0667	Aldo Keto reductase
L2Z19_02710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z19_02725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z19_02735	COG0527	aspartate kinase activity
L2Z19_02745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z19_02755	COG3038	cytochrome b561
L2Z19_02760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z19_02765	COG2252	PERMEase
L2Z19_02775	COG2072	flavoprotein involved in K transport
L2Z19_02790	COG1741	Belongs to the pirin family
L2Z19_02795	COG1309	transcriptional regulator
L2Z19_02805	COG0300	oxidoreductase activity
L2Z19_02810	COG2072	flavoprotein involved in K transport
L2Z19_02815	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L2Z19_02860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z19_02875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z19_02890	COG2814	Major facilitator Superfamily
L2Z19_02895	COG1024	Enoyl-CoA hydratase
L2Z19_02900	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_02910	COG1960	acyl-CoA dehydrogenase activity
L2Z19_02935	COG2186	Transcriptional regulator
L2Z19_02940	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_02950	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z19_02955	COG2271	Major facilitator Superfamily
L2Z19_02965	COG0697	spore germination
L2Z19_03000	COG1113	amino acid transport
L2Z19_03020	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_03040	COG0531	amino acid
L2Z19_03050	COG1113	amino acid transport
L2Z19_03085	COG3209	COG3209 Rhs family protein
L2Z19_03105	COG4269	membrane
L2Z19_03120	COG1902	pentaerythritol trinitrate reductase activity
L2Z19_03120	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z19_03130	COG3706	GGDEF domain
L2Z19_03130	COG5001	Diguanylate cyclase
L2Z19_03130	COG4251	negative regulation of phosphorylation
L2Z19_03130	COG2203	Gaf domain
L2Z19_03140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z19_03160	COG4172	Belongs to the ABC transporter superfamily
L2Z19_03165	COG4239	(ABC) transporter, permease
L2Z19_03170	COG4174	ABC transporter (Permease)
L2Z19_03180	COG0741	lytic transglycosylase activity
L2Z19_03180	COG0741	lytic transglycosylase activity
L2Z19_03180	COG1388	LysM domain
L2Z19_03180	COG1388	LysM domain
L2Z19_03185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z19_03225	COG0583	DNA-binding transcription factor activity
L2Z19_03230	COG1279	arginine transmembrane transporter activity
L2Z19_03250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z19_03255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z19_03260	COG0006	proline dipeptidase activity
L2Z19_03380	COG1196	nuclear chromosome segregation
L2Z19_03380	COG0741	lytic transglycosylase activity
L2Z19_03380	COG0739	heme binding
L2Z19_03650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z19_03670	COG3384	dioxygenase
L2Z19_03680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z19_03685	COG2878	Part of a membrane complex involved in electron transport
L2Z19_03690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z19_03715	COG0768	penicillin binding
L2Z19_03720	COG0742	ribosomal rna small subunit methyltransferase
L2Z19_03735	COG0830	nickel cation binding
L2Z19_03745	COG0804	urea catabolic process
L2Z19_03785	COG1253	flavin adenine dinucleotide binding
L2Z19_03790	COG2851	Citrate transporter
L2Z19_03840	COG1773	rubredoxin
L2Z19_03845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z19_03855	COG0583	DNA-binding transcription factor activity
L2Z19_03885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z19_03890	COG4181	ATPase activity
L2Z19_03935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z19_03955	COG0306	phosphate transporter
L2Z19_03965	COG3958	Transketolase
L2Z19_03970	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z19_03975	COG2271	Major facilitator Superfamily
L2Z19_03980	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_03985	COG0583	DNA-binding transcription factor activity
L2Z19_04000	COG2223	nitrite transmembrane transporter activity
L2Z19_04005	COG2207	Transcriptional regulator
L2Z19_04010	COG2066	Belongs to the glutaminase family
L2Z19_04015	COG0242	peptide deformylase activity
L2Z19_04020	COG0477	Major facilitator Superfamily
L2Z19_04030	COG0028	Belongs to the TPP enzyme family
L2Z19_04035	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_04045	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_04050	COG2267	carboxylic ester hydrolase activity
L2Z19_04060	COG2271	Major facilitator Superfamily
L2Z19_04075	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_04095	COG1414	Transcriptional regulator
L2Z19_04110	COG1024	Enoyl-CoA hydratase
L2Z19_04120	COG1215	transferase activity, transferring glycosyl groups
L2Z19_04125	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z19_04125	COG0726	polysaccharide deacetylase
L2Z19_04135	COG4681	YaeQ
L2Z19_04145	COG0523	cobalamin synthesis protein
L2Z19_04155	COG1607	acyl-coa hydrolase
L2Z19_04165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z19_04170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z19_04175	COG1309	transcriptional regulator
L2Z19_04200	COG2040	homocysteine
L2Z19_04205	COG0531	amino acid
L2Z19_04230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z19_04235	COG0477	Major facilitator Superfamily
L2Z19_04295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z19_04375	COG0582	viral genome integration into host DNA
L2Z19_04385	COG0405	Gamma-glutamyltransferase
L2Z19_04390	COG2814	Major facilitator Superfamily
L2Z19_04400	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z19_04415	COG1090	epimerase
L2Z19_04435	COG0420	3'-5' exonuclease activity
L2Z19_04460	COG0735	belongs to the Fur family
L2Z19_04465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z19_04485	COG0121	glutamine amidotransferase
L2Z19_04500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z19_04510	COG0210	DNA helicase
L2Z19_04515	COG2885	chlorophyll binding
L2Z19_04520	COG0204	Acyl-transferase
L2Z19_04535	COG2894	cell division
L2Z19_04555	COG1280	lysine exporter protein (LysE YggA)
L2Z19_04560	COG1674	ftsk spoiiie
L2Z19_04565	COG0492	ferredoxin-NADP+ reductase activity
L2Z19_04570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z19_04580	COG0456	acetyltransferase
L2Z19_04625	COG1981	membrane
L2Z19_04640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z19_04640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z19_04660	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_04670	COG0657	acetylesterase activity
L2Z19_04680	COG0473	3-isopropylmalate dehydrogenase activity
L2Z19_04685	COG0583	DNA-binding transcription factor activity
L2Z19_04705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z19_04730	COG0564	pseudouridine synthase activity
L2Z19_04740	COG0358	DNA primase activity
L2Z19_04755	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z19_04785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z19_04815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z19_04825	COG0351	phosphomethylpyrimidine kinase
L2Z19_04825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z19_04825	COG0352	thiamine-phosphate diphosphorylase activity
L2Z19_04830	COG1652	LysM domain
L2Z19_04855	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z19_04860	COG3101	peptidyl-lysine hydroxylation
L2Z19_04865	COG0009	L-threonylcarbamoyladenylate synthase
L2Z19_04870	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z19_04875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z19_04890	COG4106	trans-aconitate 2-methyltransferase activity
L2Z19_04905	COG2226	methyltransferase
L2Z19_04905	COG0596	Alpha beta hydrolase
L2Z19_04905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z19_04910	COG1877	trehalose-phosphatase activity
L2Z19_04915	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z19_04920	COG2223	nitrite transmembrane transporter activity
L2Z19_04940	COG1196	nuclear chromosome segregation
L2Z19_04950	COG0730	response to heat
L2Z19_04965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z19_04975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z19_05025	COG0489	protein tyrosine kinase activity
L2Z19_05035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z19_05035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z19_05065	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z19_05070	COG2081	HI0933 family
L2Z19_05080	COG0668	transmembrane transport
L2Z19_05100	COG0583	DNA-binding transcription factor activity
L2Z19_05120	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z19_05125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z19_05155	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z19_05180	COG3706	GGDEF domain
L2Z19_05195	COG0745	RESPONSE REGULATOR receiver
L2Z19_05215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z19_05255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z19_05270	COG0583	DNA-binding transcription factor activity
L2Z19_05280	COG0583	DNA-binding transcription factor activity
L2Z19_05295	COG0583	DNA-binding transcription factor activity
L2Z19_05300	COG1053	succinate dehydrogenase
L2Z19_05315	COG1309	transcriptional regulator
L2Z19_05320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z19_05325	COG2814	Major facilitator Superfamily
L2Z19_05330	COG1960	acyl-CoA dehydrogenase activity
L2Z19_05335	COG0583	DNA-binding transcription factor activity
L2Z19_05340	COG1063	alcohol dehydrogenase
L2Z19_05370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z19_05375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z19_05380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z19_05400	COG2132	Multicopper oxidase
L2Z19_05410	COG0561	phosphatase activity
L2Z19_05415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z19_05440	COG1214	PFAM Peptidase M22, glycoprotease
L2Z19_05515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z19_05520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z19_05525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z19_05585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z19_05595	COG1846	Transcriptional regulator
L2Z19_05600	COG1764	response to oxidative stress
L2Z19_05625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L2Z19_05625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L2Z19_05640	COG0037	tRNA processing
L2Z19_05650	COG0248	Ppx GppA phosphatase
L2Z19_05680	COG0072	phenylalanine-tRNA ligase activity
L2Z19_05725	COG1238	metal cluster binding
L2Z19_05730	COG0625	glutathione transferase activity
L2Z19_05745	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z19_05750	COG3028	Belongs to the UPF0307 family
L2Z19_05755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z19_05775	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z19_05780	COG0617	tRNA 3'-terminal CCA addition
L2Z19_05785	COG1555	photosystem II stabilization
L2Z19_05790	COG3956	TIGRFAM MazG family protein
L2Z19_05800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z19_05820	COG5002	protein histidine kinase activity
L2Z19_05820	COG2205	protein histidine kinase activity
L2Z19_05820	COG0784	Response regulator, receiver
L2Z19_05825	COG1024	Enoyl-CoA hydratase
L2Z19_05830	COG2084	Dehydrogenase
L2Z19_05835	COG3622	Belongs to the hyi family
L2Z19_05865	COG0697	spore germination
L2Z19_05875	COG2814	Major facilitator Superfamily
L2Z19_05880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z19_05890	COG0583	DNA-binding transcription factor activity
L2Z19_05900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z19_05910	COG0084	hydrolase, TatD family'
L2Z19_05925	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z19_05955	COG0440	acetolactate synthase activity
L2Z19_05960	COG0028	Belongs to the TPP enzyme family
L2Z19_05985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z19_05990	COG0577	efflux transmembrane transporter activity
L2Z19_05990	COG1136	(ABC) transporter
L2Z19_05995	COG1538	Outer membrane efflux protein
L2Z19_06010	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z19_06015	COG1162	GTPase activity
L2Z19_06025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z19_06065	COG1426	Protein conserved in bacteria
L2Z19_06100	COG0793	Belongs to the peptidase S41A family
L2Z19_06125	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_06130	COG3265	gluconokinase activity
L2Z19_06140	COG0800	Aldolase
L2Z19_06150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z19_06155	COG0280	phosphate acetyltransferase
L2Z19_06155	COG0857	belongs to the CobB CobQ family
L2Z19_06160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z19_06160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z19_06180	COG0740	serine-type endopeptidase activity
L2Z19_06190	COG4774	siderophore transport
L2Z19_06200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z19_06210	COG2813	Specifically methylates the guanine in position
L2Z19_06210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z19_06310	COG0788	formyltetrahydrofolate deformylase activity
L2Z19_06335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z19_06335	COG4651	solute:proton antiporter activity
L2Z19_06355	COG0724	RNA recognition motif
L2Z19_06360	COG0210	DNA helicase
L2Z19_06385	COG1733	regulation of RNA biosynthetic process
L2Z19_06395	COG2900	Belongs to the SlyX family
L2Z19_06400	COG0488	(ABC) transporter
L2Z19_06405	COG1280	lysine exporter protein (LysE YggA)
L2Z19_06410	COG1560	Kdo2-lipid A biosynthetic process
L2Z19_06420	COG1301	dicarboxylic acid transport
L2Z19_06445	COG0252	asparaginase activity
L2Z19_06475	COG0473	3-isopropylmalate dehydrogenase activity
L2Z19_06530	COG0583	DNA-binding transcription factor activity
L2Z19_06540	COG0625	glutathione transferase activity
L2Z19_06545	COG2378	regulation of single-species biofilm formation
L2Z19_06550	COG0546	phosphoglycolate phosphatase activity
L2Z19_06560	COG1530	ribonuclease E activity
L2Z19_06565	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z19_06580	COG0583	DNA-binding transcription factor activity
L2Z19_06585	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_06590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z19_06600	COG0534	Mate efflux family protein
L2Z19_06615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z19_06645	COG0493	'glutamate synthase
L2Z19_06645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z19_06655	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z19_06660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z19_06675	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z19_06685	COG0644	oxidoreductase
L2Z19_06685	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z19_06695	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z19_06700	COG4535	Mg2 and Co2 transporter CorC
L2Z19_06710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z19_06730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z19_06735	COG0475	glutathione-regulated potassium exporter activity
L2Z19_06735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z19_06750	COG0484	heat shock protein binding
L2Z19_06755	COG0789	Transcriptional regulator
L2Z19_06760	COG0598	Magnesium transport protein CorA
L2Z19_06775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z19_06780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z19_06785	COG1074	ATP-dependent DNA helicase activity
L2Z19_06790	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z19_06810	COG2226	methyltransferase
L2Z19_06820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z19_06835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z19_06850	COG2111	Na H antiporter
L2Z19_06850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z19_06855	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z19_06860	COG0651	ATP synthesis coupled electron transport
L2Z19_06865	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z19_06870	COG2212	antiporter activity
L2Z19_06875	COG1320	monovalent cation:proton antiporter activity
L2Z19_06890	COG0195	Participates in both transcription termination and antitermination
L2Z19_06945	COG0237	dephospho-CoA kinase activity
L2Z19_06955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z19_06970	COG0497	DNA recombination
L2Z19_06980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z19_07010	COG2169	Transcriptional regulator
L2Z19_07010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z19_07015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z19_07070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z19_07085	COG0326	Molecular chaperone. Has ATPase activity
L2Z19_07100	COG2056	Na+-H+ antiporter family
L2Z19_07200	COG0546	phosphoglycolate phosphatase activity
L2Z19_07205	COG1716	ATPase activity
L2Z19_07255	COG0181	hydroxymethylbilane synthase activity
L2Z19_07265	COG3275	phosphorelay sensor kinase activity
L2Z19_07290	COG0697	spore germination
L2Z19_07315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z19_07320	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z19_07325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z19_07330	COG0772	Belongs to the SEDS family
L2Z19_07355	COG4974	Belongs to the 'phage' integrase family
L2Z19_07360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z19_07370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z19_07380	COG2197	response regulator
L2Z19_07395	COG0793	Belongs to the peptidase S41A family
L2Z19_07400	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z19_07405	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z19_07445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z19_07445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z19_07455	COG0004	ammonium transporteR
L2Z19_07460	COG0347	Belongs to the P(II) protein family
L2Z19_07480	COG0659	secondary active sulfate transmembrane transporter activity
L2Z19_07485	COG0589	response to stress
L2Z19_07540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z19_07560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z19_07575	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z19_07585	COG0477	Major facilitator Superfamily
L2Z19_07590	COG2860	membrane
L2Z19_07600	COG1253	flavin adenine dinucleotide binding
L2Z19_07610	COG0477	Major facilitator Superfamily
L2Z19_07620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z19_07660	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z19_07670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z19_07740	COG0758	DNA mediated transformation
L2Z19_07750	COG0697	spore germination
L2Z19_07755	COG1309	transcriptional regulator
L2Z19_07770	COG0386	Belongs to the glutathione peroxidase family
L2Z19_07835	COG1121	(ABC) transporter
L2Z19_07840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z19_07845	COG1280	lysine exporter protein (LysE YggA)
L2Z19_07850	COG2837	iron assimilation
L2Z19_07860	COG0281	malic enzyme
L2Z19_07905	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z19_07905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z19_07910	COG4399	Belongs to the UPF0754 family
L2Z19_07915	COG2259	Doxx family
L2Z19_07920	COG0586	Pfam SNARE associated Golgi protein
L2Z19_07935	COG1192	Involved in chromosome partitioning
L2Z19_07945	COG0271	Belongs to the BolA IbaG family
L2Z19_07965	COG2267	carboxylic ester hydrolase activity
L2Z19_07985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z19_07985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z19_07985	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z19_07985	COG3321	synthase
L2Z19_07990	COG1960	acyl-CoA dehydrogenase activity
L2Z19_08000	COG2197	response regulator
L2Z19_08010	COG3916	Acyl-homoserine-lactone synthase
L2Z19_08015	COG0477	Major facilitator Superfamily
L2Z19_08020	COG1024	Enoyl-CoA hydratase
L2Z19_08025	COG1024	Enoyl-CoA hydratase
L2Z19_08030	COG1960	acyl-CoA dehydrogenase activity
L2Z19_08035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z19_08065	COG1113	amino acid transport
L2Z19_08070	COG1113	amino acid transport
L2Z19_08075	COG0251	oxidation-reduction process
L2Z19_08115	COG0564	pseudouridine synthase activity
L2Z19_08140	COG1051	belongs to the nudix hydrolase family
L2Z19_08160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z19_08175	COG1802	Transcriptional regulator
L2Z19_08185	COG1448	Aminotransferase
L2Z19_08190	COG0277	FAD linked oxidase domain protein
L2Z19_08200	COG2186	Transcriptional regulator
L2Z19_08210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z19_08215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z19_08230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z19_08245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z19_08260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z19_08295	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_08305	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_08310	COG1083	cytidylyl-transferase
L2Z19_08315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z19_08325	COG2089	acid synthase
L2Z19_08330	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z19_08335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L2Z19_08345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z19_08380	COG0728	peptidoglycan biosynthetic process
L2Z19_08385	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z19_08445	COG0546	phosphoglycolate phosphatase activity
L2Z19_08450	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_08475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z19_08480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z19_08485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z19_08490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z19_08495	COG1116	anion transmembrane transporter activity
L2Z19_08500	COG1309	transcriptional regulator
L2Z19_08505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z19_08515	COG0196	riboflavin kinase activity
L2Z19_08520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z19_08530	COG1047	Peptidyl-prolyl cis-trans
L2Z19_08570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z19_08575	COG0657	acetylesterase activity
L2Z19_08600	COG0583	DNA-binding transcription factor activity
L2Z19_08630	COG2951	lytic endotransglycosylase activity
L2Z19_08635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z19_08650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z19_08660	COG0671	phosphoesterase, PA-phosphatase related
L2Z19_08665	COG0861	Integral membrane protein TerC family
L2Z19_08680	COG0754	glutathionylspermidine amidase activity
L2Z19_08690	COG0402	S-adenosylhomocysteine deaminase activity
L2Z19_08705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z19_08710	COG1230	cation diffusion facilitator family transporter
L2Z19_08725	COG0706	membrane insertase activity
L2Z19_08750	COG0592	DNA-directed DNA polymerase activity
L2Z19_08760	COG0187	DNA topoisomerase II activity
L2Z19_08770	COG0586	Pfam SNARE associated Golgi protein
L2Z19_08775	COG0488	(ABC) transporter
L2Z19_08800	COG0596	Alpha beta hydrolase
L2Z19_08805	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z19_08810	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z19_08850	COG0733	neurotransmitter:sodium symporter activity
L2Z19_08860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L2Z19_08885	COG0583	DNA-binding transcription factor activity
L2Z19_08890	COG2233	PERMEase
L2Z19_08905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z19_08940	COG2814	Major facilitator Superfamily
L2Z19_08945	COG0656	L-ascorbic acid biosynthetic process
L2Z19_08950	COG0583	DNA-binding transcription factor activity
L2Z19_08965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z19_08970	COG1064	alcohol dehydrogenase
L2Z19_08975	COG2818	Glycosylase
L2Z19_08990	COG1194	a g-specific adenine glycosylase
L2Z19_09010	COG2983	Belongs to the UPF0260 family
L2Z19_09015	COG2133	pyrroloquinoline quinone binding
L2Z19_09020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z19_09025	COG2116	formate transmembrane transporter activity
L2Z19_09045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z19_09050	COG1335	isochorismatase
L2Z19_09055	COG0385	Bile acid
L2Z19_09060	COG0534	Mate efflux family protein
L2Z19_09065	COG1683	Conserved Protein
L2Z19_09085	COG0625	glutathione transferase activity
L2Z19_09095	COG1113	amino acid transport
L2Z19_09105	COG0523	cobalamin synthesis protein
L2Z19_09115	COG2188	Transcriptional regulator
L2Z19_09145	COG0010	Belongs to the arginase family
L2Z19_09160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z19_09165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z19_09175	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z19_09180	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z19_09280	COG0534	Mate efflux family protein
L2Z19_09285	COG0436	Aminotransferase
L2Z19_09290	COG2733	membrane
L2Z19_09305	COG2918	glutathione biosynthetic process
L2Z19_09320	COG5632	N-Acetylmuramoyl-L-alanine amidase
L2Z19_09320	COG1388	LysM domain
L2Z19_09320	COG3409	Peptidoglycan-binding domain 1 protein
L2Z19_09350	COG3150	esterase
L2Z19_09360	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z19_09370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z19_09380	COG2233	PERMEase
L2Z19_09420	COG3706	GGDEF domain
L2Z19_09435	COG1393	Belongs to the ArsC family
L2Z19_09440	COG0708	Exodeoxyribonuclease III
L2Z19_09460	COG0189	ligase activity
L2Z19_09480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z19_09490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z19_09505	COG4942	peptidase
L2Z19_09515	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z19_09525	COG2119	membrane
L2Z19_09530	COG4774	siderophore transport
L2Z19_09535	COG0426	domain, Protein
L2Z19_09535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z19_09560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z19_09580	COG1902	pentaerythritol trinitrate reductase activity
L2Z19_09585	COG1519	Transferase
L2Z19_09590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z19_09595	COG0668	transmembrane transport
L2Z19_09605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z19_09610	COG1335	isochorismatase
L2Z19_09615	COG1522	sequence-specific DNA binding
L2Z19_09640	COG0784	Response regulator, receiver
L2Z19_09640	COG2198	Histidine kinase
L2Z19_09640	COG2205	protein histidine kinase activity
L2Z19_09645	COG3162	membrane
L2Z19_09650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z19_09660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z19_09675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z19_09680	COG1309	transcriptional regulator
L2Z19_09700	COG0351	phosphomethylpyrimidine kinase
L2Z19_09700	COG0352	thiamine-phosphate diphosphorylase activity
L2Z19_09700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z19_09710	COG2814	Major facilitator Superfamily
L2Z19_09725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z19_09735	COG1113	amino acid transport
L2Z19_09745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z19_09750	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_09760	COG1335	isochorismatase
L2Z19_09790	COG2814	Major facilitator Superfamily
L2Z19_09795	COG0583	DNA-binding transcription factor activity
L2Z19_09815	COG0667	Aldo Keto reductase
L2Z19_09835	COG1733	regulation of RNA biosynthetic process
L2Z19_09840	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z19_09850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2Z19_09910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z19_09925	COG2329	Antibiotic biosynthesis monooxygenase
L2Z19_09955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z19_09985	COG0427	acetyl-CoA hydrolase
L2Z19_10010	COG0659	secondary active sulfate transmembrane transporter activity
L2Z19_10015	COG4221	oxidoreductase activity
L2Z19_10020	COG2873	o-acetylhomoserine
L2Z19_10025	COG0488	(ABC) transporter
L2Z19_10215	COG0582	viral genome integration into host DNA
L2Z19_10235	COG0833	amino acid
L2Z19_10280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z19_10285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z19_10300	COG2226	methyltransferase
L2Z19_10350	COG0067	glutamate synthase
L2Z19_10350	COG0069	glutamate synthase activity
L2Z19_10350	COG0070	glutamate synthase
L2Z19_10355	COG0493	'glutamate synthase
L2Z19_10365	COG1704	LemA family
L2Z19_10370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z19_10390	COG3307	-O-antigen
L2Z19_10410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z19_10425	COG0194	GDP metabolic process
L2Z19_10475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z19_10495	COG5380	lipid catabolic process
L2Z19_10500	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z19_10525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z19_10530	COG0277	FAD linked oxidase domain protein
L2Z19_10540	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z19_10545	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z19_10560	COG1289	transmembrane transporter activity
L2Z19_10570	COG0628	permease
L2Z19_10575	COG1192	Involved in chromosome partitioning
L2Z19_10605	COG0833	amino acid
L2Z19_10610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z19_10615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z19_10625	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_10665	COG0583	DNA-binding transcription factor activity
L2Z19_10710	COG0517	IMP dehydrogenase activity
L2Z19_10715	COG1983	PspC domain protein
L2Z19_10725	COG1960	acyl-CoA dehydrogenase activity
L2Z19_10740	COG0408	coproporphyrinogen oxidase activity
L2Z19_10760	COG0513	Belongs to the DEAD box helicase family
L2Z19_10770	COG1127	ABC transporter
L2Z19_10775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z19_10785	COG2854	intermembrane phospholipid transfer
L2Z19_10795	COG0598	Magnesium transport protein CorA
L2Z19_10805	COG0494	nUDIX hydrolase
L2Z19_10810	COG1040	competence protein
L2Z19_10815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z19_10835	COG1946	Acyl-CoA thioesterase
L2Z19_10840	COG1301	dicarboxylic acid transport
L2Z19_10855	COG1959	2 iron, 2 sulfur cluster binding
L2Z19_10860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z19_10860	COG1017	nitric oxide dioxygenase activity
L2Z19_10870	COG0433	COG0433 Predicted ATPase
L2Z19_10875	COG0626	cystathionine gamma-synthase activity
L2Z19_11030	COG1960	acyl-CoA dehydrogenase activity
L2Z19_11035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z19_11065	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z19_11070	COG0339	signal peptide processing
L2Z19_11075	COG0557	exoribonuclease II activity
L2Z19_11120	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z19_11130	COG0697	spore germination
L2Z19_11135	COG1295	ribonuclease BN
L2Z19_11170	COG1702	phosphate starvation-inducible protein PhoH
L2Z19_11180	COG0739	heme binding
L2Z19_11180	COG0741	lytic transglycosylase activity
L2Z19_11180	COG1196	nuclear chromosome segregation
L2Z19_11210	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z19_11215	COG1183	phosphatidylcholine synthase activity
L2Z19_11260	COG1960	acyl-CoA dehydrogenase activity
L2Z19_11265	COG1309	transcriptional regulator
L2Z19_11280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z19_11285	COG1960	acyl-CoA dehydrogenase activity
L2Z19_11325	COG2969	positive regulation of protein catabolic process
L2Z19_11335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z19_11350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z19_11355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z19_11375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z19_11385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z19_11390	COG1408	metallophosphoesterase
L2Z19_11400	COG2199	diguanylate cyclase activity
L2Z19_11460	COG1607	acyl-coa hydrolase
L2Z19_11490	COG2350	Protein conserved in bacteria
L2Z19_11500	COG0613	PHP domain protein
L2Z19_11505	COG3781	membrane
L2Z19_11515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z19_11520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z19_11530	COG1862	Preprotein translocase
L2Z19_11565	COG2205	protein histidine kinase activity
L2Z19_11570	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z19_11585	COG0726	polysaccharide deacetylase
L2Z19_11605	COG1091	dTDP-4-dehydrorhamnose reductase activity
L2Z19_11670	COG1960	acyl-CoA dehydrogenase activity
L2Z19_11675	COG1960	acyl-CoA dehydrogenase activity
L2Z19_11685	COG2205	protein histidine kinase activity
L2Z19_11690	COG0745	RESPONSE REGULATOR receiver
L2Z19_11695	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z19_11715	COG2096	Adenosyltransferase
L2Z19_11765	COG0285	dihydrofolate synthase activity
L2Z19_11785	COG0450	alkyl hydroperoxide reductase
L2Z19_11800	COG0477	Major facilitator Superfamily
L2Z19_11805	COG1272	protein, Hemolysin III
L2Z19_11835	COG0183	Belongs to the thiolase family
L2Z19_11840	COG2207	Transcriptional regulator
L2Z19_11860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z19_11880	COG0183	Belongs to the thiolase family
L2Z19_11890	COG2885	chlorophyll binding
L2Z19_11890	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z19_11900	COG1690	Belongs to the RtcB family
L2Z19_11905	COG0833	amino acid
L2Z19_11915	COG2233	PERMEase
L2Z19_11920	COG1217	gtp-binding protein TYPA
L2Z19_11945	COG2094	Belongs to the DNA glycosylase MPG family
L2Z19_11950	COG4772	TonB-dependent receptor
L2Z19_11955	COG1902	pentaerythritol trinitrate reductase activity
L2Z19_11970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z19_11975	COG0354	folic acid binding
L2Z19_11985	COG3189	MarR family transcriptional regulator
L2Z19_11990	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z19_11995	COG3422	double-strand break repair
L2Z19_12035	COG0840	transmembrane signaling receptor activity
L2Z19_12050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z19_12065	COG5510	response to toxic substance
L2Z19_12075	COG2832	Protein of unknown function (DUF454)
L2Z19_12080	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z19_12120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z19_12130	COG1289	transmembrane transporter activity
L2Z19_12135	COG2814	Major facilitator Superfamily
L2Z19_12155	COG1115	amino acid carrier protein
L2Z19_12160	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z19_12165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z19_12170	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z19_12175	COG3590	peptidase
L2Z19_12200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z19_12210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z19_12215	COG1077	Cell shape determining protein MreB Mrl
L2Z19_12220	COG1792	Involved in formation and maintenance of cell shape
L2Z19_12225	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z19_12230	COG0424	maF-like protein
L2Z19_12235	COG1530	ribonuclease E activity
L2Z19_12245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z19_12255	COG0560	Phosphoserine phosphatase
L2Z19_12265	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z19_12290	COG2207	Transcriptional regulator
L2Z19_12310	COG1113	amino acid transport
L2Z19_12315	COG2828	Protein conserved in bacteria
L2Z19_12320	COG0142	geranyltranstransferase activity
L2Z19_12325	COG2315	Protein conserved in bacteria
L2Z19_12340	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z19_12360	COG2194	sulfuric ester hydrolase activity
L2Z19_12365	COG0745	RESPONSE REGULATOR receiver
L2Z19_12370	COG0642	Histidine kinase
L2Z19_12380	COG0004	ammonium transporteR
L2Z19_12385	COG0583	DNA-binding transcription factor activity
L2Z19_12405	COG0525	valine-tRNA ligase activity
L2Z19_12415	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_12425	COG0393	Putative heavy-metal-binding
L2Z19_12430	COG0393	Putative heavy-metal-binding
L2Z19_12435	COG1538	Outer membrane efflux protein
L2Z19_12445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z19_12450	COG0671	phosphoesterase, PA-phosphatase related
L2Z19_12480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z19_12495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z19_12495	COG1648	precorrin-2 dehydrogenase activity
L2Z19_12500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z19_12505	COG1733	regulation of RNA biosynthetic process
L2Z19_12515	COG0531	amino acid
L2Z19_12530	COG0321	lipoyl(octanoyl) transferase activity
L2Z19_12535	COG2921	Belongs to the UPF0250 family
L2Z19_12570	COG2009	succinate dehydrogenase
L2Z19_12575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z19_12580	COG1053	succinate dehydrogenase
L2Z19_12585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z19_12610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z19_12630	COG2354	Protein conserved in bacteria
L2Z19_12635	COG2321	neutral zinc metallopeptidase
L2Z19_12655	COG2843	Capsule synthesis protein
L2Z19_12670	COG0589	response to stress
L2Z19_12680	COG0251	oxidation-reduction process
L2Z19_12700	COG0505	Belongs to the CarA family
L2Z19_12725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z19_12730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z19_12780	COG0477	Major facilitator Superfamily
L2Z19_12785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z19_12800	COG1597	lipid kinase activity
L2Z19_12805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z19_12830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z19_12835	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z19_12855	COG0741	lytic transglycosylase activity
L2Z19_12875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z19_12890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z19_12915	COG3811	Belongs to the UPF0386 family
L2Z19_12935	COG0778	Nitroreductase
L2Z19_12950	COG1929	Belongs to the glycerate kinase type-1 family
L2Z19_12955	COG0243	molybdopterin cofactor binding
L2Z19_12960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z19_12965	COG3339	Conserved Protein
L2Z19_12975	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z19_12990	COG1113	amino acid transport
L2Z19_13000	COG0019	diaminopimelate decarboxylase activity
L2Z19_13010	COG1280	lysine exporter protein (LysE YggA)
L2Z19_13015	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z19_13045	COG0463	Glycosyl transferase, family 2
L2Z19_13065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z19_13100	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z19_13105	COG1136	(ABC) transporter
L2Z19_13110	COG2333	competence protein COMEC
L2Z19_13110	COG0658	competence protein
L2Z19_13120	COG0616	signal peptide processing
L2Z19_13120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z19_13125	COG0596	Alpha beta hydrolase
L2Z19_13130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z19_13140	COG0628	permease
L2Z19_13175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z19_13195	COG0823	Involved in the tonB-independent uptake of proteins
L2Z19_13215	COG0824	Thioesterase
L2Z19_13220	COG1473	amidohydrolase
L2Z19_13240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z19_13240	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z19_13245	COG2814	Major facilitator Superfamily
L2Z19_13255	COG1024	Enoyl-CoA hydratase
L2Z19_13260	COG1051	belongs to the nudix hydrolase family
L2Z19_13260	COG1056	cytidyltransferase-related domain
L2Z19_13270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z19_13285	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z19_13300	COG4625	pathogenesis
L2Z19_13305	COG0583	DNA-binding transcription factor activity
L2Z19_13310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z19_13315	COG4208	sulfate ABC transporter
L2Z19_13320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z19_13330	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z19_13335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z19_13340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z19_13360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z19_13375	COG0681	Belongs to the peptidase S26 family
L2Z19_13390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z19_13400	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z19_13405	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z19_13415	COG4221	oxidoreductase activity
L2Z19_13445	COG0443	Heat shock 70 kDa protein
L2Z19_13455	COG0436	Aminotransferase
L2Z19_13475	COG0556	nucleotide-excision repair
L2Z19_13530	COG2070	2-Nitropropane dioxygenase
L2Z19_13560	COG1215	transferase activity, transferring glycosyl groups
L2Z19_13575	COG0415	Belongs to the DNA photolyase family
L2Z19_13585	COG1252	NADH dehydrogenase
L2Z19_13590	COG1686	Belongs to the peptidase S11 family
L2Z19_13605	COG1187	pseudouridine synthase activity
L2Z19_13630	COG0477	Major facilitator Superfamily
L2Z19_13635	COG0583	DNA-binding transcription factor activity
L2Z19_13640	COG1823	symporter activity
L2Z19_13650	COG0612	Peptidase, M16
L2Z19_13675	COG0352	thiamine-phosphate diphosphorylase activity
L2Z19_13710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z19_13720	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z19_13735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z19_13740	COG0076	glutamate decarboxylase activity
L2Z19_13750	COG1522	sequence-specific DNA binding
L2Z19_13755	COG3961	Belongs to the TPP enzyme family
L2Z19_13760	COG1113	amino acid transport
L2Z19_13765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z19_13770	COG0573	inorganic phosphate transmembrane transporter activity
L2Z19_13780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z19_13785	COG0616	signal peptide processing
L2Z19_13820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z19_13825	COG1686	Belongs to the peptidase S11 family
L2Z19_13850	COG0583	DNA-binding transcription factor activity
L2Z19_13855	COG1067	ATP-dependent peptidase activity
L2Z19_13880	COG4943	cyclic-guanylate-specific phosphodiesterase activity
L2Z19_13900	COG1966	Carbon starvation protein
L2Z19_13905	COG2879	small protein
L2Z19_13915	COG2130	NADP-dependent
L2Z19_13945	COG1741	Belongs to the pirin family
L2Z19_13955	COG2964	Protein conserved in bacteria
L2Z19_13970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z19_13975	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z19_13980	COG4605	iron ion homeostasis
L2Z19_13985	COG4604	ABC transporter, ATP-binding protein
L2Z19_13990	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z19_13995	COG4774	siderophore transport
L2Z19_14005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z19_14010	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z19_14015	COG1535	isochorismatase
L2Z19_14015	COG3433	isochorismatase activity
L2Z19_14030	COG1132	(ABC) transporter
L2Z19_14035	COG1132	(ABC) transporter
L2Z19_14040	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z19_14045	COG2977	Belongs to the P-Pant transferase superfamily
L2Z19_14050	COG1169	isochorismate synthase
L2Z19_14065	COG3739	integral membrane protein
L2Z19_14085	COG0302	gtp cyclohydrolase
L2Z19_14095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z19_14125	COG0308	aminopeptidase N
L2Z19_14130	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z19_14145	COG0174	glutamine synthetase
L2Z19_14155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z19_14190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z19_14195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z19_14200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z19_14220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z19_14225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z19_14230	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z19_14245	COG1960	acyl-CoA dehydrogenase activity
L2Z19_14250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z19_14255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z19_14265	COG2223	nitrite transmembrane transporter activity
L2Z19_14290	COG3173	Aminoglycoside phosphotransferase
L2Z19_14295	COG0488	(ABC) transporter
L2Z19_14310	COG2801	Transposase and inactivated derivatives
L2Z19_14320	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z19_14325	COG3657	addiction module killer protein
L2Z19_14365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z19_14415	COG0590	tRNA wobble adenosine to inosine editing
L2Z19_14420	COG2807	transmembrane transport
L2Z19_14435	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z19_14445	COG0789	Transcriptional regulator
L2Z19_14455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z19_14475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z19_14500	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_14505	COG0531	amino acid
L2Z19_14515	COG1760	l-serine dehydratase
L2Z19_14520	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_14520	COG2030	dehydratase
L2Z19_14525	COG3396	Phenylacetate-CoA oxygenase
L2Z19_14530	COG3460	Phenylacetate-CoA oxygenase
L2Z19_14535	COG3396	Phenylacetate-CoA oxygenase
L2Z19_14540	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z19_14545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z19_14550	COG1024	Enoyl-CoA hydratase
L2Z19_14555	COG1024	Enoyl-CoA hydratase
L2Z19_14560	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z19_14565	COG0183	Belongs to the thiolase family
L2Z19_14570	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z19_14575	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z19_14585	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z19_14610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z19_14615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z19_14620	COG2271	Major facilitator Superfamily
L2Z19_14625	COG0753	catalase activity
L2Z19_14630	COG3038	cytochrome b561
L2Z19_14650	COG2267	carboxylic ester hydrolase activity
L2Z19_14655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z19_14660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z19_14665	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_14675	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z19_14685	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_14690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z19_14695	COG0583	DNA-binding transcription factor activity
L2Z19_14705	COG1414	Transcriptional regulator
L2Z19_14710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z19_14725	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z19_14730	COG3842	ATPase activity
L2Z19_14745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z19_14750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z19_14755	COG2814	Major facilitator Superfamily
L2Z19_14760	COG1960	acyl-CoA dehydrogenase activity
L2Z19_14775	COG1024	Enoyl-CoA hydratase
L2Z19_14785	COG2814	Major facilitator Superfamily
L2Z19_14795	COG0183	Belongs to the thiolase family
L2Z19_14800	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z19_14805	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_14810	COG1024	Enoyl-CoA hydratase
L2Z19_14815	COG1960	acyl-CoA dehydrogenase activity
L2Z19_14820	COG2814	Major facilitator Superfamily
L2Z19_14825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z19_14830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z19_14840	COG2814	Major facilitator Superfamily
L2Z19_14850	COG1960	acyl-CoA dehydrogenase activity
L2Z19_14865	COG0583	DNA-binding transcription factor activity
L2Z19_14875	COG4770	biotin carboxylase activity
L2Z19_14880	COG1024	Enoyl-CoA hydratase
L2Z19_14885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z19_14890	COG1960	acyl-CoA dehydrogenase activity
L2Z19_14895	COG1309	transcriptional regulator
L2Z19_14930	COG0583	DNA-binding transcription factor activity
L2Z19_14980	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_15005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z19_15025	COG2205	protein histidine kinase activity
L2Z19_15025	COG0784	Response regulator, receiver
L2Z19_15045	COG0765	amino acid transport
L2Z19_15050	COG0765	amino acid transport
L2Z19_15060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z19_15065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z19_15080	COG1280	lysine exporter protein (LysE YggA)
L2Z19_15085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z19_15090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z19_15095	COG1045	serine acetyltransferase
L2Z19_15110	COG0583	DNA-binding transcription factor activity
L2Z19_15115	COG0625	glutathione transferase activity
L2Z19_15120	COG0625	glutathione transferase activity
L2Z19_15125	COG0583	DNA-binding transcription factor activity
L2Z19_15135	COG1346	cytolysis
L2Z19_15155	COG2814	Major facilitator Superfamily
L2Z19_15165	COG0583	DNA-binding transcription factor activity
L2Z19_15175	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z19_15180	COG3052	prosthetic group binding
L2Z19_15200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z19_15220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z19_15230	COG1294	oxidase, subunit
L2Z19_15235	COG1271	oxidase subunit
L2Z19_15255	COG0477	Major facilitator Superfamily
L2Z19_15270	COG4521	taurine ABC transporter
L2Z19_15275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z19_15280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z19_15285	COG2175	clavaminate synthase activity
L2Z19_15295	COG1953	Uracil, thiamine, allantoin
L2Z19_15305	COG0583	DNA-binding transcription factor activity
L2Z19_15315	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z19_15330	COG0640	Transcriptional regulator
L2Z19_15335	COG0798	PFAM Bile acid sodium symporter
L2Z19_15340	COG0583	DNA-binding transcription factor activity
L2Z19_15355	COG3634	alkyl hydroperoxide reductase activity
L2Z19_15395	COG0436	Aminotransferase
L2Z19_15405	COG0386	Belongs to the glutathione peroxidase family
L2Z19_15445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z19_15470	COG0012	GTP binding
L2Z19_15475	COG2011	ABC-type metal ion transport system permease component
L2Z19_15480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z19_15490	COG1464	Belongs to the NlpA lipoprotein family
L2Z19_15520	COG0765	amino acid transport
L2Z19_15525	COG0765	amino acid transport
L2Z19_15530	COG1126	abc transporter atp-binding protein
L2Z19_15540	COG1522	sequence-specific DNA binding
L2Z19_15555	COG1309	transcriptional regulator
L2Z19_15575	COG0583	DNA-binding transcription factor activity
L2Z19_15585	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z19_15595	COG0697	spore germination
L2Z19_15620	COG3121	Chaperone
L2Z19_15625	COG3539	Fimbrial protein
L2Z19_15650	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z19_15650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z19_15695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z19_15705	COG2353	YceI-like domain
L2Z19_15715	COG3698	Phosphodiester glycosidase
L2Z19_15730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z19_15735	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z19_15735	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z19_15735	COG0506	proline dehydrogenase activity
L2Z19_15745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z19_15750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z19_15770	COG1132	(ABC) transporter
L2Z19_15775	COG3122	Protein conserved in bacteria
L2Z19_15780	COG3619	membrane
L2Z19_15790	COG0640	Transcriptional regulator
L2Z19_15800	COG2850	peptidyl-arginine hydroxylation
L2Z19_15805	COG0424	maF-like protein
L2Z19_15825	COG0191	fructose-bisphosphate aldolase activity
L2Z19_15830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z19_15845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z19_15855	COG1192	Involved in chromosome partitioning
L2Z19_15860	COG1475	DNA binding
L2Z19_15865	COG0811	peptide transport
L2Z19_15875	COG1132	(ABC) transporter
L2Z19_15880	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z19_15900	COG0084	hydrolase, TatD family'
L2Z19_15965	COG0776	regulation of translation
L2Z19_15995	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z19_16000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z19_16045	COG0339	signal peptide processing
L2Z19_16055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z19_16090	COG0702	epimerase
L2Z19_16095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z19_16115	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z19_16145	COG0316	Belongs to the HesB IscA family
L2Z19_16150	COG0822	iron-sulfur transferase activity
L2Z19_16175	COG0776	regulation of translation
L2Z19_16180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z19_16185	COG2207	Transcriptional regulator
L2Z19_16190	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z19_16195	COG1960	acyl-CoA dehydrogenase activity
L2Z19_16200	COG1960	acyl-CoA dehydrogenase activity
L2Z19_16215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z19_16230	COG2814	Major facilitator Superfamily
L2Z19_16235	COG4264	IucA IucC family
L2Z19_16240	COG4264	IucA IucC family
L2Z19_16250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z19_16280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z19_16295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z19_16300	COG0406	alpha-ribazole phosphatase activity
L2Z19_16315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z19_16320	COG0730	response to heat
L2Z19_16340	COG4773	Receptor
L2Z19_16345	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z19_16360	COG1131	(ABC) transporter
L2Z19_16365	COG0842	Transport permease protein
L2Z19_16370	COG0842	Transport permease protein
L2Z19_16425	COG2226	methyltransferase
L2Z19_16450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z19_16485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z19_16495	COG0133	tryptophan synthase activity
L2Z19_16525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z19_16530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z19_16535	COG0022	dehydrogenase e1 component
L2Z19_16540	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z19_16545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z19_16555	COG1063	alcohol dehydrogenase
L2Z19_16560	COG3781	membrane
L2Z19_16585	COG0730	response to heat
L2Z19_16600	COG3708	Transcriptional regulator
L2Z19_16600	COG2207	Transcriptional regulator
L2Z19_16605	COG1733	regulation of RNA biosynthetic process
L2Z19_16610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z19_16620	COG2188	Transcriptional regulator
L2Z19_16635	COG4521	taurine ABC transporter
L2Z19_16640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z19_16660	COG0477	Major facilitator Superfamily
L2Z19_16670	COG1027	Aspartate ammonia-lyase
L2Z19_16685	COG0583	DNA-binding transcription factor activity
L2Z19_16690	COG0583	DNA-binding transcription factor activity
L2Z19_16695	COG0183	Belongs to the thiolase family
L2Z19_16700	COG2031	fatty acid transporter
L2Z19_16715	COG0583	DNA-binding transcription factor activity
L2Z19_16745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z19_16750	COG2610	gluconate transmembrane transporter activity
L2Z19_16755	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_16760	COG2207	Transcriptional regulator
L2Z19_16775	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_16785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z19_16800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z19_16800	COG0543	2 iron, 2 sulfur cluster binding
L2Z19_16805	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z19_16810	COG4638	Rieske (2fe-2S)
L2Z19_16820	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z19_16825	COG4149	molybdate abc transporter
L2Z19_16830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z19_16835	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_16840	COG3433	isochorismatase activity
L2Z19_16840	COG1535	isochorismatase
L2Z19_16900	COG3293	Transposase
L2Z19_16910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z19_16925	COG0753	catalase activity
L2Z19_16935	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z19_16945	COG3293	Transposase
L2Z19_16965	COG3539	Fimbrial protein
L2Z19_16980	COG4372	Transposase
L2Z19_17050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z19_17055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z19_17060	COG0745	RESPONSE REGULATOR receiver
L2Z19_17075	COG2207	Transcriptional regulator
L2Z19_17085	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_17090	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_17180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z19_17200	COG1120	ATPase activity
L2Z19_17205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z19_17215	COG1064	alcohol dehydrogenase
L2Z19_17220	COG2207	Transcriptional regulator
L2Z19_17225	COG2084	Dehydrogenase
L2Z19_17235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z19_17240	COG0583	DNA-binding transcription factor activity
L2Z19_17250	COG0129	dihydroxy-acid dehydratase activity
L2Z19_17255	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_17260	COG1846	Transcriptional regulator
L2Z19_17265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z19_17270	COG1960	acyl-CoA dehydrogenase activity
L2Z19_17275	COG0477	Major facilitator Superfamily
L2Z19_17290	COG3971	2-oxopent-4-enoate hydratase activity
L2Z19_17300	COG3384	dioxygenase
L2Z19_17305	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_17315	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z19_17325	COG2814	Major facilitator Superfamily
L2Z19_17330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z19_17365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z19_17385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z19_17415	COG1566	PFAM secretion protein HlyD family protein
L2Z19_17450	COG0583	DNA-binding transcription factor activity
L2Z19_17465	COG2188	Transcriptional regulator
L2Z19_17515	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z19_17525	COG1960	acyl-CoA dehydrogenase activity
L2Z19_17535	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_17540	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_17545	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_17550	COG0583	DNA-binding transcription factor activity
L2Z19_17555	COG1309	transcriptional regulator
L2Z19_17585	COG0789	Transcriptional regulator
L2Z19_17600	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z19_17600	COG1902	pentaerythritol trinitrate reductase activity
L2Z19_17615	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_17635	COG2186	Transcriptional regulator
L2Z19_17645	COG0583	DNA-binding transcription factor activity
L2Z19_17650	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z19_17655	COG4829	muconolactone delta-isomerase
L2Z19_17665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z19_17670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z19_17675	COG0183	Belongs to the thiolase family
L2Z19_17680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z19_17685	COG1012	belongs to the aldehyde dehydrogenase family
L2Z19_17695	COG3733	amine oxidase
L2Z19_17705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z19_17715	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z19_17725	COG4638	Rieske (2fe-2S)
L2Z19_17745	COG0154	amidase activity
L2Z19_17755	COG2814	Major facilitator Superfamily
L2Z19_17780	COG1960	acyl-CoA dehydrogenase activity
L2Z19_17785	COG0583	DNA-binding transcription factor activity
L2Z19_17790	COG1414	Transcriptional regulator
L2Z19_17805	COG2391	methyltransferase activity
L2Z19_17815	COG4993	Dehydrogenase
L2Z19_17820	COG3659	wide pore channel activity
L2Z19_17825	COG3420	alginic acid biosynthetic process
L2Z19_17830	COG0710	3-dehydroquinate dehydratase activity
L2Z19_17835	COG3485	protocatechuate 3,4-dioxygenase
L2Z19_17840	COG3485	protocatechuate 3,4-dioxygenase
L2Z19_17845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z19_17850	COG2271	Major facilitator Superfamily
L2Z19_17855	COG0596	Alpha beta hydrolase
L2Z19_17860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z19_17865	COG0183	Belongs to the thiolase family
L2Z19_17870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z19_17875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z19_17885	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z19_17890	COG2323	membrane
L2Z19_17935	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z19_17935	COG1902	pentaerythritol trinitrate reductase activity
L2Z19_17960	COG0542	response to heat
L2Z19_17965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z19_17995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z19_18000	COG0569	domain protein
L2Z19_18005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z19_18020	COG4774	siderophore transport
L2Z19_18025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z19_18035	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z19_18050	COG1294	oxidase, subunit
L2Z19_18055	COG4890	Cyd operon protein YbgT
L2Z19_18065	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z19_18075	COG0552	protein localization to endoplasmic reticulum
L2Z19_18100	COG0516	GMP reductase activity
L2Z19_18100	COG0517	IMP dehydrogenase activity
L2Z19_18105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z19_18110	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z19_18120	COG0583	DNA-binding transcription factor activity
L2Z19_18125	COG0024	Methionine aminopeptidase
L2Z19_18155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z19_18155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z19_18160	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z19_18165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z19_18165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z19_18165	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z19_18200	COG2135	peptidase activity
L2Z19_18205	COG0659	secondary active sulfate transmembrane transporter activity
L2Z19_18225	COG1113	amino acid transport
L2Z19_18235	COG1522	sequence-specific DNA binding
L2Z19_18260	COG1011	Hydrolase
L2Z19_18265	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z19_18275	COG2137	regulation of response to DNA damage stimulus
L2Z19_18290	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z19_18310	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z19_18325	COG0575	Belongs to the CDS family
L2Z19_18330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z19_18355	COG3852	Histidine kinase
L2Z19_18360	COG2204	response regulator
L2Z19_18415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z19_18420	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z19_18440	COG0697	spore germination
L2Z19_18445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z19_18455	COG0303	'Molybdopterin
L2Z19_18460	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z19_18460	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z19_18475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z19_18480	COG0243	molybdopterin cofactor binding
L2Z19_18490	COG0243	molybdopterin cofactor binding
L2Z19_18495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z19_18500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z19_18500	COG2146	nitrite reductase [NAD(P)H] activity
L2Z19_18510	COG0745	RESPONSE REGULATOR receiver
L2Z19_18515	COG1116	anion transmembrane transporter activity
L2Z19_18515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z19_18535	COG0511	ligase activity, forming carbon-carbon bonds
L2Z19_18550	COG2814	Major facilitator Superfamily
L2Z19_18645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z19_18720	COG1525	nuclease
L2Z19_18785	COG1192	Involved in chromosome partitioning
L2Z19_18795	COG1475	DNA binding
L2Z19_18810	COG3853	Toxic anion resistance protein (TelA)
L2Z19_18925	COG0484	heat shock protein binding
L2Z19_19080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process