locus-tag	class	description
L2Z20_00035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z20_00045	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z20_00085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z20_00095	COG0477	Major facilitator Superfamily
L2Z20_00105	COG1253	flavin adenine dinucleotide binding
L2Z20_00110	COG3012	SEC-C Motif Domain Protein
L2Z20_00115	COG2860	membrane
L2Z20_00120	COG0477	Major facilitator Superfamily
L2Z20_00130	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z20_00145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z20_00165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z20_00235	COG0659	secondary active sulfate transmembrane transporter activity
L2Z20_00260	COG0789	Transcriptional regulator
L2Z20_00345	COG0347	Belongs to the P(II) protein family
L2Z20_00365	COG0004	ammonium transporteR
L2Z20_00375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z20_00375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z20_00415	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z20_00420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z20_00425	COG0793	Belongs to the peptidase S41A family
L2Z20_00440	COG2197	response regulator
L2Z20_00450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z20_00460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z20_00465	COG4974	Belongs to the 'phage' integrase family
L2Z20_00490	COG0772	Belongs to the SEDS family
L2Z20_00495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z20_00500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z20_00505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z20_00530	COG0697	spore germination
L2Z20_00535	COG1538	Outer membrane efflux protein
L2Z20_00555	COG3275	phosphorelay sensor kinase activity
L2Z20_00565	COG0181	hydroxymethylbilane synthase activity
L2Z20_00610	COG1716	ATPase activity
L2Z20_00615	COG0546	phosphoglycolate phosphatase activity
L2Z20_00715	COG2056	Na+-H+ antiporter family
L2Z20_00730	COG0326	Molecular chaperone. Has ATPase activity
L2Z20_00745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z20_00805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z20_00810	COG2169	Transcriptional regulator
L2Z20_00810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z20_00840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z20_00850	COG0497	DNA recombination
L2Z20_00865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z20_00875	COG0237	dephospho-CoA kinase activity
L2Z20_00930	COG0195	Participates in both transcription termination and antitermination
L2Z20_00945	COG1320	monovalent cation:proton antiporter activity
L2Z20_00950	COG2212	antiporter activity
L2Z20_00955	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z20_00960	COG0651	ATP synthesis coupled electron transport
L2Z20_00965	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z20_00970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z20_00970	COG2111	Na H antiporter
L2Z20_00985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z20_00990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z20_01005	COG2226	methyltransferase
L2Z20_01025	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z20_01030	COG1074	ATP-dependent DNA helicase activity
L2Z20_01035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z20_01040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z20_01055	COG0598	Magnesium transport protein CorA
L2Z20_01060	COG0789	Transcriptional regulator
L2Z20_01065	COG0484	heat shock protein binding
L2Z20_01080	COG0475	glutathione-regulated potassium exporter activity
L2Z20_01080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z20_01085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z20_01105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z20_01115	COG4535	Mg2 and Co2 transporter CorC
L2Z20_01120	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z20_01130	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z20_01130	COG0644	oxidoreductase
L2Z20_01140	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z20_01155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z20_01160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z20_01170	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z20_01170	COG0493	'glutamate synthase
L2Z20_01195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z20_01210	COG0534	Mate efflux family protein
L2Z20_01220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z20_01225	COG4221	oxidoreductase activity
L2Z20_01230	COG0583	DNA-binding transcription factor activity
L2Z20_01245	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z20_01250	COG1530	ribonuclease E activity
L2Z20_01265	COG0546	phosphoglycolate phosphatase activity
L2Z20_01270	COG2378	regulation of single-species biofilm formation
L2Z20_01275	COG0625	glutathione transferase activity
L2Z20_01285	COG0583	DNA-binding transcription factor activity
L2Z20_01340	COG0473	3-isopropylmalate dehydrogenase activity
L2Z20_01395	COG1301	dicarboxylic acid transport
L2Z20_01405	COG1560	Kdo2-lipid A biosynthetic process
L2Z20_01410	COG1280	lysine exporter protein (LysE YggA)
L2Z20_01415	COG0488	(ABC) transporter
L2Z20_01420	COG2900	Belongs to the SlyX family
L2Z20_01430	COG1733	regulation of RNA biosynthetic process
L2Z20_01455	COG0210	DNA helicase
L2Z20_01460	COG0724	RNA recognition motif
L2Z20_01480	COG4651	solute:proton antiporter activity
L2Z20_01480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z20_01505	COG0788	formyltetrahydrofolate deformylase activity
L2Z20_01605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z20_01605	COG2813	Specifically methylates the guanine in position
L2Z20_01615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z20_01625	COG4774	siderophore transport
L2Z20_01635	COG0740	serine-type endopeptidase activity
L2Z20_01655	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z20_01655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z20_01660	COG0280	phosphate acetyltransferase
L2Z20_01660	COG0857	belongs to the CobB CobQ family
L2Z20_01665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z20_01675	COG0800	Aldolase
L2Z20_01685	COG3265	gluconokinase activity
L2Z20_01690	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_01700	COG2267	carboxylic ester hydrolase activity
L2Z20_01715	COG0793	Belongs to the peptidase S41A family
L2Z20_01750	COG1426	Protein conserved in bacteria
L2Z20_01790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z20_01800	COG1162	GTPase activity
L2Z20_01805	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z20_01820	COG1538	Outer membrane efflux protein
L2Z20_01825	COG0577	efflux transmembrane transporter activity
L2Z20_01825	COG1136	(ABC) transporter
L2Z20_01830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z20_01855	COG0028	Belongs to the TPP enzyme family
L2Z20_01860	COG0440	acetolactate synthase activity
L2Z20_01890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z20_01905	COG0084	hydrolase, TatD family'
L2Z20_01915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z20_01925	COG0583	DNA-binding transcription factor activity
L2Z20_01935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z20_01940	COG2814	Major facilitator Superfamily
L2Z20_01950	COG0697	spore germination
L2Z20_01980	COG3622	Belongs to the hyi family
L2Z20_01985	COG2084	Dehydrogenase
L2Z20_01990	COG1024	Enoyl-CoA hydratase
L2Z20_01995	COG5002	protein histidine kinase activity
L2Z20_01995	COG2205	protein histidine kinase activity
L2Z20_01995	COG0784	Response regulator, receiver
L2Z20_02015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z20_02025	COG3956	TIGRFAM MazG family protein
L2Z20_02030	COG1555	photosystem II stabilization
L2Z20_02035	COG0617	tRNA 3'-terminal CCA addition
L2Z20_02040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z20_02060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z20_02065	COG3028	Belongs to the UPF0307 family
L2Z20_02070	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z20_02085	COG0625	glutathione transferase activity
L2Z20_02090	COG1238	metal cluster binding
L2Z20_02095	COG2826	transposase and inactivated derivatives, IS30 family
L2Z20_02135	COG0072	phenylalanine-tRNA ligase activity
L2Z20_02165	COG0248	Ppx GppA phosphatase
L2Z20_02175	COG0037	tRNA processing
L2Z20_02215	COG1764	response to oxidative stress
L2Z20_02220	COG1846	Transcriptional regulator
L2Z20_02230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z20_02290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z20_02295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z20_02300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z20_02310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z20_02360	COG1214	PFAM Peptidase M22, glycoprotease
L2Z20_02375	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L2Z20_02385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z20_02390	COG0561	phosphatase activity
L2Z20_02400	COG2132	Multicopper oxidase
L2Z20_02405	COG3667	copper resistance
L2Z20_02420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z20_02425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z20_02430	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z20_02460	COG1063	alcohol dehydrogenase
L2Z20_02465	COG0583	DNA-binding transcription factor activity
L2Z20_02470	COG1960	acyl-CoA dehydrogenase activity
L2Z20_02475	COG2814	Major facilitator Superfamily
L2Z20_02480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z20_02490	COG1053	succinate dehydrogenase
L2Z20_02495	COG0583	DNA-binding transcription factor activity
L2Z20_02510	COG0583	DNA-binding transcription factor activity
L2Z20_02540	COG0583	DNA-binding transcription factor activity
L2Z20_02555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z20_02560	COG1309	transcriptional regulator
L2Z20_02570	COG2826	transposase and inactivated derivatives, IS30 family
L2Z20_02590	COG0384	phenazine biosynthesis protein PhzF
L2Z20_02600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z20_02620	COG0745	RESPONSE REGULATOR receiver
L2Z20_02660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z20_02690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z20_02695	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z20_02720	COG0583	DNA-binding transcription factor activity
L2Z20_02740	COG0668	transmembrane transport
L2Z20_02750	COG2081	HI0933 family
L2Z20_02755	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z20_02785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z20_02785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z20_02795	COG0489	protein tyrosine kinase activity
L2Z20_02845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z20_02855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z20_02870	COG0730	response to heat
L2Z20_02880	COG1196	nuclear chromosome segregation
L2Z20_02900	COG2223	nitrite transmembrane transporter activity
L2Z20_02905	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z20_02915	COG2226	methyltransferase
L2Z20_02915	COG0596	Alpha beta hydrolase
L2Z20_02915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z20_02930	COG4106	trans-aconitate 2-methyltransferase activity
L2Z20_02945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z20_02950	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z20_02955	COG0009	L-threonylcarbamoyladenylate synthase
L2Z20_02960	COG3101	peptidyl-lysine hydroxylation
L2Z20_02965	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z20_02990	COG1652	LysM domain
L2Z20_02995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z20_02995	COG0352	thiamine-phosphate diphosphorylase activity
L2Z20_02995	COG0351	phosphomethylpyrimidine kinase
L2Z20_03005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z20_03035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z20_03065	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z20_03080	COG0358	DNA primase activity
L2Z20_03090	COG0564	pseudouridine synthase activity
L2Z20_03115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z20_03135	COG0583	DNA-binding transcription factor activity
L2Z20_03140	COG0473	3-isopropylmalate dehydrogenase activity
L2Z20_03150	COG0657	acetylesterase activity
L2Z20_03160	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_03180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z20_03180	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z20_03195	COG1981	membrane
L2Z20_03240	COG0456	acetyltransferase
L2Z20_03250	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z20_03255	COG0492	ferredoxin-NADP+ reductase activity
L2Z20_03260	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z20_03260	COG1674	ftsk spoiiie
L2Z20_03265	COG1280	lysine exporter protein (LysE YggA)
L2Z20_03280	COG2894	cell division
L2Z20_03295	COG0204	Acyl-transferase
L2Z20_03300	COG2885	chlorophyll binding
L2Z20_03305	COG0210	DNA helicase
L2Z20_03315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z20_03330	COG0121	glutamine amidotransferase
L2Z20_03350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z20_03355	COG0735	belongs to the Fur family
L2Z20_03380	COG0420	3'-5' exonuclease activity
L2Z20_03400	COG1090	epimerase
L2Z20_03415	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z20_03425	COG2814	Major facilitator Superfamily
L2Z20_03430	COG0405	Gamma-glutamyltransferase
L2Z20_03440	COG0582	viral genome integration into host DNA
L2Z20_03495	COG0629	single-stranded DNA binding
L2Z20_03500	COG2826	transposase and inactivated derivatives, IS30 family
L2Z20_03520	COG2826	transposase and inactivated derivatives, IS30 family
L2Z20_03550	COG0084	hydrolase, TatD family'
L2Z20_03570	COG0477	Major facilitator Superfamily
L2Z20_03575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z20_03585	COG1595	DNA-templated transcription, initiation
L2Z20_03640	COG0531	amino acid
L2Z20_03645	COG2040	homocysteine
L2Z20_03670	COG1309	transcriptional regulator
L2Z20_03675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z20_03680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z20_03690	COG1607	acyl-coa hydrolase
L2Z20_03700	COG0523	cobalamin synthesis protein
L2Z20_03710	COG4681	YaeQ
L2Z20_03720	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z20_03720	COG0726	polysaccharide deacetylase
L2Z20_03725	COG1215	transferase activity, transferring glycosyl groups
L2Z20_03735	COG1024	Enoyl-CoA hydratase
L2Z20_03750	COG1414	Transcriptional regulator
L2Z20_03770	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_03780	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z20_03785	COG2271	Major facilitator Superfamily
L2Z20_03795	COG2267	carboxylic ester hydrolase activity
L2Z20_03800	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_03815	COG0028	Belongs to the TPP enzyme family
L2Z20_03825	COG0477	Major facilitator Superfamily
L2Z20_03830	COG0242	peptide deformylase activity
L2Z20_03835	COG2066	Belongs to the glutaminase family
L2Z20_03840	COG2207	Transcriptional regulator
L2Z20_03845	COG2223	nitrite transmembrane transporter activity
L2Z20_03860	COG0583	DNA-binding transcription factor activity
L2Z20_03865	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_03870	COG2271	Major facilitator Superfamily
L2Z20_03875	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z20_03880	COG3958	Transketolase
L2Z20_03890	COG0306	phosphate transporter
L2Z20_03910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z20_03955	COG4181	ATPase activity
L2Z20_03960	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z20_03985	COG0583	DNA-binding transcription factor activity
L2Z20_03995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z20_04000	COG1773	rubredoxin
L2Z20_04050	COG2851	Citrate transporter
L2Z20_04055	COG1253	flavin adenine dinucleotide binding
L2Z20_04100	COG0804	urea catabolic process
L2Z20_04110	COG0830	nickel cation binding
L2Z20_04125	COG0742	ribosomal rna small subunit methyltransferase
L2Z20_04130	COG0768	penicillin binding
L2Z20_04155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z20_04160	COG2878	Part of a membrane complex involved in electron transport
L2Z20_04165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z20_04175	COG3384	dioxygenase
L2Z20_04200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z20_04525	COG0739	heme binding
L2Z20_04575	COG4372	Transposase
L2Z20_04625	COG0006	proline dipeptidase activity
L2Z20_04630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z20_04635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z20_04655	COG1279	arginine transmembrane transporter activity
L2Z20_04660	COG0583	DNA-binding transcription factor activity
L2Z20_04700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z20_04705	COG0741	lytic transglycosylase activity
L2Z20_04705	COG1388	LysM domain
L2Z20_04705	COG1388	LysM domain
L2Z20_04705	COG0741	lytic transglycosylase activity
L2Z20_04715	COG4174	ABC transporter (Permease)
L2Z20_04720	COG4239	(ABC) transporter, permease
L2Z20_04725	COG4172	Belongs to the ABC transporter superfamily
L2Z20_04745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z20_04755	COG3706	GGDEF domain
L2Z20_04755	COG2203	Gaf domain
L2Z20_04755	COG5001	Diguanylate cyclase
L2Z20_04755	COG4251	negative regulation of phosphorylation
L2Z20_04765	COG1902	pentaerythritol trinitrate reductase activity
L2Z20_04765	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z20_04780	COG4269	membrane
L2Z20_04810	COG3209	COG3209 Rhs family protein
L2Z20_04850	COG1113	amino acid transport
L2Z20_04860	COG0531	amino acid
L2Z20_04880	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_04900	COG1113	amino acid transport
L2Z20_04915	COG0697	spore germination
L2Z20_04920	COG2721	sulfolactate sulfo-lyase activity
L2Z20_04925	COG2271	Major facilitator Superfamily
L2Z20_04930	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z20_04940	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_04945	COG2186	Transcriptional regulator
L2Z20_05115	COG0300	oxidoreductase activity
L2Z20_05125	COG1309	transcriptional regulator
L2Z20_05130	COG1741	Belongs to the pirin family
L2Z20_05145	COG2072	flavoprotein involved in K transport
L2Z20_05155	COG2252	PERMEase
L2Z20_05160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z20_05165	COG3038	cytochrome b561
L2Z20_05175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z20_05185	COG0527	aspartate kinase activity
L2Z20_05195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z20_05205	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z20_05220	COG0667	Aldo Keto reductase
L2Z20_05240	COG1765	OsmC-like protein
L2Z20_05255	COG0542	response to heat
L2Z20_05290	COG2885	chlorophyll binding
L2Z20_05300	COG0625	glutathione transferase activity
L2Z20_05305	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z20_05325	COG3634	alkyl hydroperoxide reductase activity
L2Z20_05335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z20_05345	COG0450	alkyl hydroperoxide reductase
L2Z20_05350	COG1643	Atp-dependent helicase
L2Z20_05365	COG2814	Major facilitator Superfamily
L2Z20_05370	COG3135	benzoate transporter
L2Z20_05375	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_05380	COG0633	Ferredoxin
L2Z20_05380	COG0543	2 iron, 2 sulfur cluster binding
L2Z20_05385	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z20_05390	COG4638	Rieske (2fe-2S)
L2Z20_05400	COG0583	DNA-binding transcription factor activity
L2Z20_05450	COG1570	exodeoxyribonuclease VII activity
L2Z20_05480	COG1280	lysine exporter protein (LysE YggA)
L2Z20_05485	COG1278	Cold shock
L2Z20_05520	COG2814	Major facilitator Superfamily
L2Z20_05555	COG0517	IMP dehydrogenase activity
L2Z20_05555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z20_05560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z20_05570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z20_05575	COG1137	ATPase activity
L2Z20_05585	COG4372	Transposase
L2Z20_05630	COG4122	O-methyltransferase activity
L2Z20_05640	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z20_05655	COG1522	sequence-specific DNA binding
L2Z20_05660	COG5006	permease, DMT superfamily
L2Z20_05670	COG1560	Kdo2-lipid A biosynthetic process
L2Z20_05685	COG2814	Major facilitator Superfamily
L2Z20_05705	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z20_05735	COG4372	Transposase
L2Z20_05775	COG0583	DNA-binding transcription factor activity
L2Z20_05780	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z20_05800	COG4770	biotin carboxylase activity
L2Z20_05805	COG0038	chloride channel
L2Z20_05825	COG1309	transcriptional regulator
L2Z20_05835	COG1063	alcohol dehydrogenase
L2Z20_05850	COG0439	Biotin carboxylase
L2Z20_05855	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z20_05875	COG0864	Transcriptional regulator
L2Z20_05885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z20_05890	COG1116	anion transmembrane transporter activity
L2Z20_06010	COG0590	tRNA wobble adenosine to inosine editing
L2Z20_06015	COG2807	transmembrane transport
L2Z20_06030	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z20_06040	COG0789	Transcriptional regulator
L2Z20_06050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z20_06070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z20_06080	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z20_06095	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_06100	COG0531	amino acid
L2Z20_06105	COG1760	l-serine dehydratase
L2Z20_06110	COG2030	dehydratase
L2Z20_06110	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_06115	COG3396	Phenylacetate-CoA oxygenase
L2Z20_06120	COG3460	Phenylacetate-CoA oxygenase
L2Z20_06125	COG3396	Phenylacetate-CoA oxygenase
L2Z20_06130	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z20_06135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z20_06145	COG3293	Transposase
L2Z20_06155	COG1024	Enoyl-CoA hydratase
L2Z20_06160	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z20_06165	COG0183	Belongs to the thiolase family
L2Z20_06170	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z20_06175	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z20_06185	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z20_06220	COG0753	catalase activity
L2Z20_06225	COG3038	cytochrome b561
L2Z20_06245	COG2267	carboxylic ester hydrolase activity
L2Z20_06250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z20_06255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z20_06260	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_06270	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z20_06280	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_06285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z20_06290	COG0583	DNA-binding transcription factor activity
L2Z20_06300	COG1414	Transcriptional regulator
L2Z20_06305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z20_06315	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z20_06320	COG3842	ATPase activity
L2Z20_06335	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z20_06340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z20_06345	COG2814	Major facilitator Superfamily
L2Z20_06350	COG1960	acyl-CoA dehydrogenase activity
L2Z20_06365	COG1024	Enoyl-CoA hydratase
L2Z20_06375	COG2814	Major facilitator Superfamily
L2Z20_06385	COG0183	Belongs to the thiolase family
L2Z20_06390	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z20_06395	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_06400	COG1024	Enoyl-CoA hydratase
L2Z20_06405	COG1960	acyl-CoA dehydrogenase activity
L2Z20_06410	COG2814	Major facilitator Superfamily
L2Z20_06415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z20_06420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z20_06430	COG2814	Major facilitator Superfamily
L2Z20_06440	COG1960	acyl-CoA dehydrogenase activity
L2Z20_06455	COG0583	DNA-binding transcription factor activity
L2Z20_06465	COG4770	biotin carboxylase activity
L2Z20_06470	COG1024	Enoyl-CoA hydratase
L2Z20_06475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z20_06480	COG1960	acyl-CoA dehydrogenase activity
L2Z20_06485	COG1309	transcriptional regulator
L2Z20_06490	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z20_06510	COG0583	DNA-binding transcription factor activity
L2Z20_06560	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_06580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z20_06600	COG0784	Response regulator, receiver
L2Z20_06600	COG2205	protein histidine kinase activity
L2Z20_06620	COG0765	amino acid transport
L2Z20_06625	COG0765	amino acid transport
L2Z20_06630	COG1126	abc transporter atp-binding protein
L2Z20_06635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z20_06640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z20_06655	COG1280	lysine exporter protein (LysE YggA)
L2Z20_06665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z20_06670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z20_06675	COG1045	serine acetyltransferase
L2Z20_06690	COG0583	DNA-binding transcription factor activity
L2Z20_06695	COG0625	glutathione transferase activity
L2Z20_06700	COG0625	glutathione transferase activity
L2Z20_06705	COG0583	DNA-binding transcription factor activity
L2Z20_06715	COG1346	cytolysis
L2Z20_06735	COG2814	Major facilitator Superfamily
L2Z20_06745	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z20_06750	COG3052	prosthetic group binding
L2Z20_06770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z20_06790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z20_06800	COG1294	oxidase, subunit
L2Z20_06805	COG1271	oxidase subunit
L2Z20_06830	COG0477	Major facilitator Superfamily
L2Z20_06840	COG4521	taurine ABC transporter
L2Z20_06845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z20_06850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z20_06855	COG2175	clavaminate synthase activity
L2Z20_06865	COG1953	Uracil, thiamine, allantoin
L2Z20_06875	COG0583	DNA-binding transcription factor activity
L2Z20_06885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z20_06900	COG0640	Transcriptional regulator
L2Z20_06905	COG0798	PFAM Bile acid sodium symporter
L2Z20_06910	COG0583	DNA-binding transcription factor activity
L2Z20_06925	COG3634	alkyl hydroperoxide reductase activity
L2Z20_06965	COG0436	Aminotransferase
L2Z20_06975	COG0386	Belongs to the glutathione peroxidase family
L2Z20_07015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z20_07040	COG0012	GTP binding
L2Z20_07045	COG2011	ABC-type metal ion transport system permease component
L2Z20_07050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z20_07060	COG1464	Belongs to the NlpA lipoprotein family
L2Z20_07090	COG0765	amino acid transport
L2Z20_07095	COG0765	amino acid transport
L2Z20_07100	COG1126	abc transporter atp-binding protein
L2Z20_07110	COG1522	sequence-specific DNA binding
L2Z20_07155	COG0583	DNA-binding transcription factor activity
L2Z20_07165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z20_07175	COG0697	spore germination
L2Z20_07200	COG3121	Chaperone
L2Z20_07205	COG3539	Fimbrial protein
L2Z20_07230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z20_07230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z20_07275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z20_07285	COG2353	YceI-like domain
L2Z20_07310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z20_07315	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z20_07315	COG0506	proline dehydrogenase activity
L2Z20_07315	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z20_07325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z20_07340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z20_07360	COG1132	(ABC) transporter
L2Z20_07365	COG3122	Protein conserved in bacteria
L2Z20_07370	COG3619	membrane
L2Z20_07380	COG0640	Transcriptional regulator
L2Z20_07390	COG2850	peptidyl-arginine hydroxylation
L2Z20_07395	COG0424	maF-like protein
L2Z20_07415	COG0191	fructose-bisphosphate aldolase activity
L2Z20_07420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z20_07435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z20_07445	COG1192	Involved in chromosome partitioning
L2Z20_07450	COG1475	DNA binding
L2Z20_07455	COG0811	peptide transport
L2Z20_07465	COG1132	(ABC) transporter
L2Z20_07470	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z20_07490	COG0084	hydrolase, TatD family'
L2Z20_07555	COG0776	regulation of translation
L2Z20_07585	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z20_07590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z20_07640	COG0339	signal peptide processing
L2Z20_07650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z20_07685	COG0702	epimerase
L2Z20_07690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z20_07710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z20_07740	COG0316	Belongs to the HesB IscA family
L2Z20_07745	COG0822	iron-sulfur transferase activity
L2Z20_07770	COG0776	regulation of translation
L2Z20_07775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z20_07780	COG2207	Transcriptional regulator
L2Z20_07785	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z20_07790	COG1960	acyl-CoA dehydrogenase activity
L2Z20_07795	COG1960	acyl-CoA dehydrogenase activity
L2Z20_07810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z20_07830	COG4264	IucA IucC family
L2Z20_07835	COG4264	IucA IucC family
L2Z20_07875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z20_07890	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z20_07910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z20_07915	COG0730	response to heat
L2Z20_07935	COG4773	Receptor
L2Z20_07940	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z20_07955	COG1131	(ABC) transporter
L2Z20_07960	COG0842	Transport permease protein
L2Z20_07965	COG0842	Transport permease protein
L2Z20_08020	COG2226	methyltransferase
L2Z20_08050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z20_08085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z20_08095	COG0133	tryptophan synthase activity
L2Z20_08110	COG3706	GGDEF domain
L2Z20_08125	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z20_08130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z20_08135	COG0022	dehydrogenase e1 component
L2Z20_08140	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z20_08145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z20_08155	COG1063	alcohol dehydrogenase
L2Z20_08160	COG3781	membrane
L2Z20_08170	COG3453	Protein conserved in bacteria
L2Z20_08170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z20_08185	COG0730	response to heat
L2Z20_08200	COG2207	Transcriptional regulator
L2Z20_08200	COG3708	Transcriptional regulator
L2Z20_08205	COG1733	regulation of RNA biosynthetic process
L2Z20_08210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z20_08220	COG2188	Transcriptional regulator
L2Z20_08235	COG4521	taurine ABC transporter
L2Z20_08240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z20_08260	COG0477	Major facilitator Superfamily
L2Z20_08270	COG1027	Aspartate ammonia-lyase
L2Z20_08285	COG0583	DNA-binding transcription factor activity
L2Z20_08290	COG0583	DNA-binding transcription factor activity
L2Z20_08295	COG0183	Belongs to the thiolase family
L2Z20_08300	COG2031	fatty acid transporter
L2Z20_08305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z20_08315	COG0583	DNA-binding transcription factor activity
L2Z20_08325	COG2610	gluconate transmembrane transporter activity
L2Z20_08330	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_08335	COG2207	Transcriptional regulator
L2Z20_08350	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_08375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z20_08375	COG0543	2 iron, 2 sulfur cluster binding
L2Z20_08380	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z20_08385	COG4638	Rieske (2fe-2S)
L2Z20_08395	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z20_08400	COG4149	molybdate abc transporter
L2Z20_08405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z20_08410	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_08415	COG1535	isochorismatase
L2Z20_08415	COG3433	isochorismatase activity
L2Z20_08475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z20_08490	COG0753	catalase activity
L2Z20_08500	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z20_08525	COG3539	Fimbrial protein
L2Z20_08540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z20_08560	COG2072	flavoprotein involved in K transport
L2Z20_08570	COG1538	Outer membrane efflux protein
L2Z20_08575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z20_08580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z20_08585	COG0745	RESPONSE REGULATOR receiver
L2Z20_08590	COG2205	protein histidine kinase activity
L2Z20_08600	COG2207	Transcriptional regulator
L2Z20_08615	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_08660	COG3293	Transposase
L2Z20_08675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z20_08795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z20_08815	COG1120	ATPase activity
L2Z20_08820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z20_08830	COG1064	alcohol dehydrogenase
L2Z20_08845	COG2207	Transcriptional regulator
L2Z20_08850	COG2084	Dehydrogenase
L2Z20_08860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z20_08865	COG0583	DNA-binding transcription factor activity
L2Z20_08875	COG0129	dihydroxy-acid dehydratase activity
L2Z20_08880	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_08895	COG1566	PFAM secretion protein HlyD family protein
L2Z20_08925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z20_08955	COG0583	DNA-binding transcription factor activity
L2Z20_08970	COG2188	Transcriptional regulator
L2Z20_09000	COG3210	domain, Protein
L2Z20_09020	COG4372	Transposase
L2Z20_09035	COG1473	amidohydrolase
L2Z20_09045	COG0475	glutathione-regulated potassium exporter activity
L2Z20_09045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z20_09055	COG0583	DNA-binding transcription factor activity
L2Z20_09060	COG1335	isochorismatase
L2Z20_09070	COG1309	transcriptional regulator
L2Z20_09100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z20_09110	COG1902	pentaerythritol trinitrate reductase activity
L2Z20_09110	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z20_09115	COG1846	Transcriptional regulator
L2Z20_09140	COG0753	catalase activity
L2Z20_09155	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_09170	COG3162	membrane
L2Z20_09180	COG3829	transcription factor binding
L2Z20_09185	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_09190	COG1960	acyl-CoA dehydrogenase activity
L2Z20_09210	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_09230	COG2186	Transcriptional regulator
L2Z20_09240	COG0583	DNA-binding transcription factor activity
L2Z20_09245	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z20_09250	COG4829	muconolactone delta-isomerase
L2Z20_09260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z20_09265	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z20_09270	COG0183	Belongs to the thiolase family
L2Z20_09275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z20_09285	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_09295	COG3733	amine oxidase
L2Z20_09305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z20_09315	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_09325	COG4638	Rieske (2fe-2S)
L2Z20_09345	COG0154	amidase activity
L2Z20_09355	COG2814	Major facilitator Superfamily
L2Z20_09380	COG1960	acyl-CoA dehydrogenase activity
L2Z20_09385	COG0583	DNA-binding transcription factor activity
L2Z20_09390	COG1414	Transcriptional regulator
L2Z20_09405	COG2391	methyltransferase activity
L2Z20_09415	COG4993	Dehydrogenase
L2Z20_09420	COG3659	wide pore channel activity
L2Z20_09425	COG3420	alginic acid biosynthetic process
L2Z20_09430	COG0710	3-dehydroquinate dehydratase activity
L2Z20_09435	COG3485	protocatechuate 3,4-dioxygenase
L2Z20_09440	COG3485	protocatechuate 3,4-dioxygenase
L2Z20_09445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z20_09450	COG2271	Major facilitator Superfamily
L2Z20_09455	COG0596	Alpha beta hydrolase
L2Z20_09460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z20_09465	COG0183	Belongs to the thiolase family
L2Z20_09470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z20_09475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z20_09485	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z20_09490	COG2323	membrane
L2Z20_09535	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z20_09535	COG1902	pentaerythritol trinitrate reductase activity
L2Z20_09560	COG0542	response to heat
L2Z20_09565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z20_09595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z20_09600	COG0569	domain protein
L2Z20_09605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z20_09620	COG4774	siderophore transport
L2Z20_09625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z20_09635	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z20_09650	COG1294	oxidase, subunit
L2Z20_09655	COG4890	Cyd operon protein YbgT
L2Z20_09670	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z20_09680	COG0552	protein localization to endoplasmic reticulum
L2Z20_09705	COG0517	IMP dehydrogenase activity
L2Z20_09705	COG0516	GMP reductase activity
L2Z20_09710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z20_09715	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z20_09725	COG0583	DNA-binding transcription factor activity
L2Z20_09730	COG0024	Methionine aminopeptidase
L2Z20_09760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z20_09760	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z20_09765	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z20_09770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z20_09770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z20_09770	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z20_09790	COG3300	MHYT domain
L2Z20_09790	COG5001	Diguanylate cyclase
L2Z20_09810	COG4372	Transposase
L2Z20_09820	COG2135	peptidase activity
L2Z20_09825	COG0659	secondary active sulfate transmembrane transporter activity
L2Z20_09845	COG1113	amino acid transport
L2Z20_09855	COG1522	sequence-specific DNA binding
L2Z20_09880	COG1011	Hydrolase
L2Z20_09885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z20_09895	COG2137	regulation of response to DNA damage stimulus
L2Z20_09910	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z20_09945	COG0575	Belongs to the CDS family
L2Z20_09950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z20_09970	COG3852	Histidine kinase
L2Z20_09975	COG2204	response regulator
L2Z20_10030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z20_10035	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z20_10055	COG0697	spore germination
L2Z20_10060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z20_10070	COG0303	'Molybdopterin
L2Z20_10075	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z20_10075	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z20_10090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z20_10095	COG0243	molybdopterin cofactor binding
L2Z20_10105	COG0243	molybdopterin cofactor binding
L2Z20_10110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z20_10115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z20_10115	COG2146	nitrite reductase [NAD(P)H] activity
L2Z20_10125	COG0745	RESPONSE REGULATOR receiver
L2Z20_10130	COG1116	anion transmembrane transporter activity
L2Z20_10130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z20_10150	COG0511	ligase activity, forming carbon-carbon bonds
L2Z20_10165	COG2814	Major facilitator Superfamily
L2Z20_10185	COG0069	glutamate synthase activity
L2Z20_10205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z20_10215	COG1454	alcohol dehydrogenase
L2Z20_10220	COG0824	Thioesterase
L2Z20_10230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z20_10245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z20_10250	COG2030	dehydratase
L2Z20_10260	COG0183	Belongs to the thiolase family
L2Z20_10270	COG0583	DNA-binding transcription factor activity
L2Z20_10275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z20_10285	COG1522	sequence-specific DNA binding
L2Z20_10290	COG3135	benzoate transporter
L2Z20_10300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z20_10325	COG0589	response to stress
L2Z20_10330	COG0488	(ABC) transporter
L2Z20_10350	COG4773	Receptor
L2Z20_10380	COG0668	transmembrane transport
L2Z20_10390	COG1309	transcriptional regulator
L2Z20_10410	COG1605	Chorismate mutase
L2Z20_10420	COG4221	oxidoreductase activity
L2Z20_10430	COG0308	aminopeptidase N
L2Z20_10450	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z20_10460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z20_10465	COG1454	alcohol dehydrogenase
L2Z20_10485	COG0531	amino acid
L2Z20_10490	COG4303	Ethanolamine ammonia lyase large subunit
L2Z20_10495	COG4302	ethanolamine ammonia-lyase activity
L2Z20_10500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z20_10500	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z20_10505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z20_10515	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z20_10530	COG0697	spore germination
L2Z20_10535	COG1923	regulation of RNA biosynthetic process
L2Z20_10545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z20_10550	COG0802	atpase or kinase
L2Z20_10570	COG1187	pseudouridine synthase activity
L2Z20_10585	COG0583	DNA-binding transcription factor activity
L2Z20_10600	COG2814	Major facilitator Superfamily
L2Z20_10605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z20_10630	COG0729	surface antigen
L2Z20_10650	COG0174	glutamine synthetase
L2Z20_10655	COG0745	RESPONSE REGULATOR receiver
L2Z20_10660	COG2205	protein histidine kinase activity
L2Z20_10670	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z20_10675	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z20_10700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z20_10705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z20_10710	COG1960	acyl-CoA dehydrogenase activity
L2Z20_10725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z20_10730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z20_10750	COG0583	DNA-binding transcription factor activity
L2Z20_10765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z20_10775	COG3658	cytochrome
L2Z20_10780	COG1215	transferase activity, transferring glycosyl groups
L2Z20_10785	COG0726	polysaccharide deacetylase
L2Z20_10785	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z20_10810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z20_10815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z20_10825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z20_10855	COG0305	Participates in initiation and elongation during chromosome replication
L2Z20_10860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z20_10870	COG1305	Transglutaminase-like
L2Z20_10880	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z20_10910	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z20_10915	COG0138	bifunctional purine biosynthesis protein purh
L2Z20_10920	COG0151	Belongs to the GarS family
L2Z20_10925	COG1464	Belongs to the NlpA lipoprotein family
L2Z20_10930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z20_10935	COG2011	ABC-type metal ion transport system permease component
L2Z20_10940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z20_10950	COG1301	dicarboxylic acid transport
L2Z20_10980	COG1794	racemase activity, acting on amino acids and derivatives
L2Z20_10990	COG3008	intermembrane lipid transfer
L2Z20_10990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z20_10995	COG2995	paraquat-inducible protein a
L2Z20_11005	COG2985	domain, Protein
L2Z20_11035	COG0477	Major facilitator Superfamily
L2Z20_11085	COG2186	Transcriptional regulator
L2Z20_11095	COG0786	glutamate:sodium symporter activity
L2Z20_11100	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z20_11125	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z20_11225	COG1610	YqeY-like protein
L2Z20_11230	COG4783	chaperone-mediated protein folding
L2Z20_11255	COG1286	toxin biosynthetic process
L2Z20_11285	COG0778	Nitroreductase
L2Z20_11295	COG0513	Belongs to the DEAD box helicase family
L2Z20_11325	COG2363	Small membrane protein
L2Z20_11355	COG1234	tRNA 3'-trailer cleavage
L2Z20_11360	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z20_11370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z20_11380	COG2819	hydrolase of the alpha beta superfamily
L2Z20_11385	COG1960	acyl-CoA dehydrogenase activity
L2Z20_11390	COG1301	dicarboxylic acid transport
L2Z20_11395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z20_11400	COG3139	Protein of unknown function (DUF1315)
L2Z20_11405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z20_11410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z20_11420	COG0494	nUDIX hydrolase
L2Z20_11430	COG0642	Histidine kinase
L2Z20_11445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z20_11455	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z20_11470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z20_11475	COG0826	peptidase U32
L2Z20_11480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z20_11490	COG4598	ABC transporter
L2Z20_11495	COG4160	amino acid transport
L2Z20_11500	COG4215	(ABC) transporter
L2Z20_11515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z20_11560	COG1131	(ABC) transporter
L2Z20_11565	COG0842	Transport permease protein
L2Z20_11580	COG0772	Belongs to the SEDS family
L2Z20_11585	COG2951	lytic endotransglycosylase activity
L2Z20_11610	COG2207	Transcriptional regulator
L2Z20_11625	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z20_11630	COG0024	Methionine aminopeptidase
L2Z20_11640	COG2223	nitrite transmembrane transporter activity
L2Z20_11650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z20_11655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z20_11660	COG1960	acyl-CoA dehydrogenase activity
L2Z20_11675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z20_11680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z20_11685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z20_11705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z20_11715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z20_11720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z20_11755	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z20_11765	COG0174	glutamine synthetase
L2Z20_11780	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z20_11815	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z20_11825	COG0302	gtp cyclohydrolase
L2Z20_11850	COG3739	integral membrane protein
L2Z20_11865	COG1169	isochorismate synthase
L2Z20_11875	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z20_11880	COG1132	(ABC) transporter
L2Z20_11885	COG1132	(ABC) transporter
L2Z20_11900	COG1535	isochorismatase
L2Z20_11900	COG3433	isochorismatase activity
L2Z20_11905	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z20_11910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z20_11920	COG4774	siderophore transport
L2Z20_11925	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z20_11930	COG4604	ABC transporter, ATP-binding protein
L2Z20_11935	COG4605	iron ion homeostasis
L2Z20_11940	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z20_11945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z20_11960	COG2964	Protein conserved in bacteria
L2Z20_11970	COG1741	Belongs to the pirin family
L2Z20_11990	COG1309	transcriptional regulator
L2Z20_12000	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z20_12005	COG2814	Major facilitator Superfamily
L2Z20_12040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z20_12040	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z20_12045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z20_12055	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_12065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z20_12070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z20_12075	COG0583	DNA-binding transcription factor activity
L2Z20_12080	COG1113	amino acid transport
L2Z20_12090	COG4372	Transposase
L2Z20_12120	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z20_12120	COG2508	Transcriptional regulator
L2Z20_12155	COG2879	small protein
L2Z20_12160	COG1966	Carbon starvation protein
L2Z20_12205	COG1067	ATP-dependent peptidase activity
L2Z20_12210	COG0583	DNA-binding transcription factor activity
L2Z20_12235	COG1686	Belongs to the peptidase S11 family
L2Z20_12240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z20_12275	COG0616	signal peptide processing
L2Z20_12280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z20_12290	COG0573	inorganic phosphate transmembrane transporter activity
L2Z20_12295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z20_12300	COG1113	amino acid transport
L2Z20_12305	COG3961	Belongs to the TPP enzyme family
L2Z20_12310	COG1522	sequence-specific DNA binding
L2Z20_12320	COG0076	glutamate decarboxylase activity
L2Z20_12325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z20_12335	COG1309	transcriptional regulator
L2Z20_12350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z20_12385	COG0352	thiamine-phosphate diphosphorylase activity
L2Z20_12410	COG0612	Peptidase, M16
L2Z20_12420	COG1823	symporter activity
L2Z20_12425	COG0583	DNA-binding transcription factor activity
L2Z20_12430	COG0477	Major facilitator Superfamily
L2Z20_12450	COG1187	pseudouridine synthase activity
L2Z20_12480	COG1252	NADH dehydrogenase
L2Z20_12490	COG0415	Belongs to the DNA photolyase family
L2Z20_12505	COG1215	transferase activity, transferring glycosyl groups
L2Z20_12535	COG2070	2-Nitropropane dioxygenase
L2Z20_12590	COG0556	nucleotide-excision repair
L2Z20_12610	COG0436	Aminotransferase
L2Z20_12640	COG4221	oxidoreductase activity
L2Z20_12650	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z20_12655	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z20_12665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z20_12680	COG0681	Belongs to the peptidase S26 family
L2Z20_12695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z20_12715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z20_12720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z20_12725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z20_12735	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z20_12740	COG4208	sulfate ABC transporter
L2Z20_12745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z20_12750	COG0583	DNA-binding transcription factor activity
L2Z20_12755	COG4625	pathogenesis
L2Z20_12770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z20_12785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z20_12795	COG1051	belongs to the nudix hydrolase family
L2Z20_12795	COG1056	cytidyltransferase-related domain
L2Z20_12800	COG1024	Enoyl-CoA hydratase
L2Z20_12810	COG2814	Major facilitator Superfamily
L2Z20_12815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z20_12815	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z20_12835	COG1473	amidohydrolase
L2Z20_12840	COG0824	Thioesterase
L2Z20_12860	COG0823	Involved in the tonB-independent uptake of proteins
L2Z20_12880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z20_12915	COG0628	permease
L2Z20_12925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z20_12930	COG0596	Alpha beta hydrolase
L2Z20_12935	COG0616	signal peptide processing
L2Z20_12935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z20_12945	COG0658	competence protein
L2Z20_12945	COG2333	competence protein COMEC
L2Z20_12950	COG1136	(ABC) transporter
L2Z20_12955	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z20_12985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z20_13035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z20_13040	COG1280	lysine exporter protein (LysE YggA)
L2Z20_13045	COG2267	carboxylic ester hydrolase activity
L2Z20_13055	COG0019	diaminopimelate decarboxylase activity
L2Z20_13065	COG1113	amino acid transport
L2Z20_13080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z20_13090	COG3339	Conserved Protein
L2Z20_13095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z20_13100	COG0243	molybdopterin cofactor binding
L2Z20_13105	COG1929	Belongs to the glycerate kinase type-1 family
L2Z20_13120	COG0778	Nitroreductase
L2Z20_13150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z20_13165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z20_13185	COG0741	lytic transglycosylase activity
L2Z20_13205	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z20_13210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z20_13235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z20_13240	COG1597	lipid kinase activity
L2Z20_13255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z20_13260	COG0477	Major facilitator Superfamily
L2Z20_13310	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z20_13315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z20_13340	COG0505	Belongs to the CarA family
L2Z20_13360	COG0589	response to stress
L2Z20_13375	COG2843	Capsule synthesis protein
L2Z20_13395	COG2321	neutral zinc metallopeptidase
L2Z20_13400	COG2354	Protein conserved in bacteria
L2Z20_13420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z20_13445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z20_13450	COG1053	succinate dehydrogenase
L2Z20_13455	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z20_13460	COG2009	succinate dehydrogenase
L2Z20_13500	COG2921	Belongs to the UPF0250 family
L2Z20_13505	COG0321	lipoyl(octanoyl) transferase activity
L2Z20_13520	COG0531	amino acid
L2Z20_13530	COG1733	regulation of RNA biosynthetic process
L2Z20_13535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z20_13540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z20_13540	COG1648	precorrin-2 dehydrogenase activity
L2Z20_13555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z20_13585	COG0671	phosphoesterase, PA-phosphatase related
L2Z20_13590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z20_13600	COG1538	Outer membrane efflux protein
L2Z20_13605	COG0393	Putative heavy-metal-binding
L2Z20_13610	COG0393	Putative heavy-metal-binding
L2Z20_13620	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_13630	COG0525	valine-tRNA ligase activity
L2Z20_13650	COG0583	DNA-binding transcription factor activity
L2Z20_13655	COG0004	ammonium transporteR
L2Z20_13665	COG0642	Histidine kinase
L2Z20_13670	COG0745	RESPONSE REGULATOR receiver
L2Z20_13680	COG4372	Transposase
L2Z20_13715	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z20_13730	COG2315	Protein conserved in bacteria
L2Z20_13735	COG0142	geranyltranstransferase activity
L2Z20_13740	COG2828	Protein conserved in bacteria
L2Z20_13745	COG1113	amino acid transport
L2Z20_13765	COG2207	Transcriptional regulator
L2Z20_13790	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z20_13800	COG0560	Phosphoserine phosphatase
L2Z20_13810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z20_13820	COG1530	ribonuclease E activity
L2Z20_13825	COG0424	maF-like protein
L2Z20_13830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z20_13835	COG1792	Involved in formation and maintenance of cell shape
L2Z20_13840	COG1077	Cell shape determining protein MreB Mrl
L2Z20_13845	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z20_13855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z20_13880	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z20_13885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z20_13890	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z20_13895	COG1115	amino acid carrier protein
L2Z20_13915	COG2814	Major facilitator Superfamily
L2Z20_13920	COG1289	transmembrane transporter activity
L2Z20_13930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z20_13970	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z20_13975	COG2832	Protein of unknown function (DUF454)
L2Z20_13985	COG5510	response to toxic substance
L2Z20_14015	COG0840	transmembrane signaling receptor activity
L2Z20_14055	COG3422	double-strand break repair
L2Z20_14060	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z20_14065	COG3189	MarR family transcriptional regulator
L2Z20_14075	COG0354	folic acid binding
L2Z20_14080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z20_14090	COG0679	Auxin Efflux Carrier
L2Z20_14095	COG1902	pentaerythritol trinitrate reductase activity
L2Z20_14100	COG4772	TonB-dependent receptor
L2Z20_14105	COG2094	Belongs to the DNA glycosylase MPG family
L2Z20_14130	COG1217	gtp-binding protein TYPA
L2Z20_14135	COG2233	PERMEase
L2Z20_14145	COG0833	amino acid
L2Z20_14150	COG1690	Belongs to the RtcB family
L2Z20_14160	COG2885	chlorophyll binding
L2Z20_14160	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z20_14170	COG0183	Belongs to the thiolase family
L2Z20_14190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z20_14210	COG2207	Transcriptional regulator
L2Z20_14215	COG0183	Belongs to the thiolase family
L2Z20_14235	COG2153	protein acetylation
L2Z20_14245	COG1272	protein, Hemolysin III
L2Z20_14250	COG0477	Major facilitator Superfamily
L2Z20_14265	COG0450	alkyl hydroperoxide reductase
L2Z20_14285	COG0285	dihydrofolate synthase activity
L2Z20_14335	COG2096	Adenosyltransferase
L2Z20_14355	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z20_14360	COG0745	RESPONSE REGULATOR receiver
L2Z20_14365	COG2205	protein histidine kinase activity
L2Z20_14375	COG1960	acyl-CoA dehydrogenase activity
L2Z20_14380	COG1960	acyl-CoA dehydrogenase activity
L2Z20_14430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z20_14445	COG0438	transferase activity, transferring glycosyl groups
L2Z20_14450	COG0463	Glycosyl transferase, family 2
L2Z20_14455	COG0726	polysaccharide deacetylase
L2Z20_14475	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z20_14480	COG2205	protein histidine kinase activity
L2Z20_14630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L2Z20_14640	COG3646	Phage regulatory protein
L2Z20_14685	COG0629	single-stranded DNA binding
L2Z20_14690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z20_14735	COG1862	Preprotein translocase
L2Z20_14750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z20_14760	COG3781	membrane
L2Z20_14765	COG0613	PHP domain protein
L2Z20_14775	COG2350	Protein conserved in bacteria
L2Z20_14805	COG1607	acyl-coa hydrolase
L2Z20_14865	COG2199	diguanylate cyclase activity
L2Z20_14875	COG1408	metallophosphoesterase
L2Z20_14880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z20_14890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z20_14910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z20_14915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z20_14930	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z20_14940	COG2969	positive regulation of protein catabolic process
L2Z20_14960	COG1960	acyl-CoA dehydrogenase activity
L2Z20_14965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z20_14980	COG1309	transcriptional regulator
L2Z20_14985	COG1960	acyl-CoA dehydrogenase activity
L2Z20_15030	COG1183	phosphatidylcholine synthase activity
L2Z20_15035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z20_15065	COG0739	heme binding
L2Z20_15065	COG1196	nuclear chromosome segregation
L2Z20_15065	COG0741	lytic transglycosylase activity
L2Z20_15075	COG1702	phosphate starvation-inducible protein PhoH
L2Z20_15110	COG1295	ribonuclease BN
L2Z20_15115	COG0697	spore germination
L2Z20_15120	COG2169	Transcriptional regulator
L2Z20_15125	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z20_15170	COG0557	exoribonuclease II activity
L2Z20_15175	COG0339	signal peptide processing
L2Z20_15180	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z20_15210	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z20_15215	COG1960	acyl-CoA dehydrogenase activity
L2Z20_15370	COG0626	cystathionine gamma-synthase activity
L2Z20_15375	COG0433	COG0433 Predicted ATPase
L2Z20_15380	COG1017	nitric oxide dioxygenase activity
L2Z20_15380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z20_15385	COG1959	2 iron, 2 sulfur cluster binding
L2Z20_15400	COG1301	dicarboxylic acid transport
L2Z20_15405	COG1946	Acyl-CoA thioesterase
L2Z20_15425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z20_15430	COG1040	competence protein
L2Z20_15435	COG0494	nUDIX hydrolase
L2Z20_15445	COG0598	Magnesium transport protein CorA
L2Z20_15455	COG2854	intermembrane phospholipid transfer
L2Z20_15465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z20_15470	COG1127	ABC transporter
L2Z20_15480	COG0513	Belongs to the DEAD box helicase family
L2Z20_15500	COG0408	coproporphyrinogen oxidase activity
L2Z20_15515	COG1960	acyl-CoA dehydrogenase activity
L2Z20_15525	COG1983	PspC domain protein
L2Z20_15530	COG0517	IMP dehydrogenase activity
L2Z20_15580	COG0583	DNA-binding transcription factor activity
L2Z20_15620	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_15630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z20_15635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z20_15640	COG0833	amino acid
L2Z20_15670	COG1192	Involved in chromosome partitioning
L2Z20_15675	COG0628	permease
L2Z20_15685	COG1289	transmembrane transporter activity
L2Z20_15700	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z20_15705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z20_15715	COG0277	FAD linked oxidase domain protein
L2Z20_15720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z20_15745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z20_15750	COG5380	lipid catabolic process
L2Z20_15770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z20_15820	COG0194	GDP metabolic process
L2Z20_15835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z20_15870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z20_15875	COG1704	LemA family
L2Z20_15885	COG0493	'glutamate synthase
L2Z20_15890	COG0069	glutamate synthase activity
L2Z20_15890	COG0067	glutamate synthase
L2Z20_15890	COG0070	glutamate synthase
L2Z20_15940	COG2226	methyltransferase
L2Z20_15955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z20_15960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z20_16005	COG0833	amino acid
L2Z20_16070	COG0488	(ABC) transporter
L2Z20_16075	COG2873	o-acetylhomoserine
L2Z20_16080	COG4221	oxidoreductase activity
L2Z20_16085	COG0659	secondary active sulfate transmembrane transporter activity
L2Z20_16110	COG0427	acetyl-CoA hydrolase
L2Z20_16140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z20_16180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z20_16240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2Z20_16250	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z20_16255	COG1733	regulation of RNA biosynthetic process
L2Z20_16270	COG1733	regulation of RNA biosynthetic process
L2Z20_16290	COG0667	Aldo Keto reductase
L2Z20_16310	COG0583	DNA-binding transcription factor activity
L2Z20_16315	COG2814	Major facilitator Superfamily
L2Z20_16345	COG1335	isochorismatase
L2Z20_16355	COG1012	belongs to the aldehyde dehydrogenase family
L2Z20_16360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z20_16370	COG1113	amino acid transport
L2Z20_16380	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z20_16395	COG2814	Major facilitator Superfamily
L2Z20_16405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z20_16405	COG0352	thiamine-phosphate diphosphorylase activity
L2Z20_16405	COG0351	phosphomethylpyrimidine kinase
L2Z20_16425	COG1309	transcriptional regulator
L2Z20_16430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z20_16445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z20_16455	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z20_16460	COG3162	membrane
L2Z20_16465	COG0784	Response regulator, receiver
L2Z20_16465	COG2198	Histidine kinase
L2Z20_16465	COG2205	protein histidine kinase activity
L2Z20_16490	COG1522	sequence-specific DNA binding
L2Z20_16495	COG1335	isochorismatase
L2Z20_16500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z20_16510	COG0668	transmembrane transport
L2Z20_16515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z20_16520	COG1519	Transferase
L2Z20_16525	COG1902	pentaerythritol trinitrate reductase activity
L2Z20_16545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z20_16570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z20_16570	COG0426	domain, Protein
L2Z20_16575	COG4774	siderophore transport
L2Z20_16580	COG2119	membrane
L2Z20_16590	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z20_16600	COG4942	peptidase
L2Z20_16615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z20_16625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z20_16645	COG0189	ligase activity
L2Z20_16665	COG0708	Exodeoxyribonuclease III
L2Z20_16670	COG1393	Belongs to the ArsC family
L2Z20_16685	COG3706	GGDEF domain
L2Z20_16720	COG2351	hydroxyisourate hydrolase activity
L2Z20_16725	COG2233	PERMEase
L2Z20_16735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z20_16745	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z20_16755	COG3150	esterase
L2Z20_16810	COG2918	glutathione biosynthetic process
L2Z20_16825	COG2733	membrane
L2Z20_16830	COG0436	Aminotransferase
L2Z20_16835	COG0534	Mate efflux family protein
L2Z20_16920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z20_16925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z20_16935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z20_16945	COG2205	protein histidine kinase activity
L2Z20_16950	COG2826	transposase and inactivated derivatives, IS30 family
L2Z20_16955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z20_16970	COG0010	Belongs to the arginase family
L2Z20_17000	COG2188	Transcriptional regulator
L2Z20_17010	COG0523	cobalamin synthesis protein
L2Z20_17020	COG1113	amino acid transport
L2Z20_17030	COG0625	glutathione transferase activity
L2Z20_17050	COG1683	Conserved Protein
L2Z20_17055	COG0534	Mate efflux family protein
L2Z20_17060	COG0385	Bile acid
L2Z20_17065	COG1335	isochorismatase
L2Z20_17070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z20_17090	COG2116	formate transmembrane transporter activity
L2Z20_17095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z20_17100	COG2133	pyrroloquinoline quinone binding
L2Z20_17105	COG2983	Belongs to the UPF0260 family
L2Z20_17125	COG1194	a g-specific adenine glycosylase
L2Z20_17140	COG2818	Glycosylase
L2Z20_17145	COG1064	alcohol dehydrogenase
L2Z20_17150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z20_17165	COG0583	DNA-binding transcription factor activity
L2Z20_17170	COG0656	L-ascorbic acid biosynthetic process
L2Z20_17175	COG2814	Major facilitator Superfamily
L2Z20_17210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z20_17225	COG2233	PERMEase
L2Z20_17230	COG0583	DNA-binding transcription factor activity
L2Z20_17265	COG0733	neurotransmitter:sodium symporter activity
L2Z20_17305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z20_17310	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z20_17315	COG0596	Alpha beta hydrolase
L2Z20_17340	COG0488	(ABC) transporter
L2Z20_17345	COG0586	Pfam SNARE associated Golgi protein
L2Z20_17355	COG0187	DNA topoisomerase II activity
L2Z20_17365	COG0592	DNA-directed DNA polymerase activity
L2Z20_17390	COG0706	membrane insertase activity
L2Z20_17405	COG1230	cation diffusion facilitator family transporter
L2Z20_17410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z20_17425	COG0402	S-adenosylhomocysteine deaminase activity
L2Z20_17435	COG0754	glutathionylspermidine amidase activity
L2Z20_17445	COG0861	Integral membrane protein TerC family
L2Z20_17450	COG0671	phosphoesterase, PA-phosphatase related
L2Z20_17460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z20_17475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z20_17480	COG2951	lytic endotransglycosylase activity
L2Z20_17510	COG0583	DNA-binding transcription factor activity
L2Z20_17530	COG0657	acetylesterase activity
L2Z20_17535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z20_17575	COG1047	Peptidyl-prolyl cis-trans
L2Z20_17585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z20_17590	COG0196	riboflavin kinase activity
L2Z20_17600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z20_17605	COG1309	transcriptional regulator
L2Z20_17610	COG1116	anion transmembrane transporter activity
L2Z20_17615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z20_17620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z20_17625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z20_17630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z20_17650	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z20_17655	COG0546	phosphoglycolate phosphatase activity
L2Z20_17710	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z20_17715	COG0728	peptidoglycan biosynthetic process
L2Z20_17755	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z20_17760	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z20_17765	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z20_17795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z20_17800	COG0110	maltose O-acetyltransferase activity
L2Z20_17810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z20_17825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z20_17830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z20_17840	COG2186	Transcriptional regulator
L2Z20_17850	COG0277	FAD linked oxidase domain protein
L2Z20_17855	COG1448	Aminotransferase
L2Z20_17860	COG1802	Transcriptional regulator
L2Z20_17875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z20_17925	COG0564	pseudouridine synthase activity
L2Z20_17965	COG0251	oxidation-reduction process
L2Z20_17970	COG1113	amino acid transport
L2Z20_17975	COG1113	amino acid transport
L2Z20_17995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z20_18000	COG1960	acyl-CoA dehydrogenase activity
L2Z20_18005	COG1024	Enoyl-CoA hydratase
L2Z20_18010	COG1024	Enoyl-CoA hydratase
L2Z20_18015	COG0477	Major facilitator Superfamily
L2Z20_18020	COG3916	Acyl-homoserine-lactone synthase
L2Z20_18030	COG2197	response regulator
L2Z20_18040	COG1960	acyl-CoA dehydrogenase activity
L2Z20_18045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z20_18045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z20_18045	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z20_18045	COG3321	synthase
L2Z20_18065	COG2267	carboxylic ester hydrolase activity
L2Z20_18085	COG0271	Belongs to the BolA IbaG family
L2Z20_18095	COG1192	Involved in chromosome partitioning
L2Z20_18110	COG0586	Pfam SNARE associated Golgi protein
L2Z20_18115	COG2259	Doxx family
L2Z20_18120	COG4399	Belongs to the UPF0754 family
L2Z20_18125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z20_18125	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z20_18170	COG0281	malic enzyme
L2Z20_18175	COG2837	iron assimilation
L2Z20_18180	COG1280	lysine exporter protein (LysE YggA)
L2Z20_18185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z20_18190	COG1121	(ABC) transporter
L2Z20_18255	COG0386	Belongs to the glutathione peroxidase family
L2Z20_18270	COG1309	transcriptional regulator
L2Z20_18275	COG0697	spore germination
L2Z20_18285	COG0758	DNA mediated transformation
L2Z20_18395	COG3293	Transposase