locus-tag	class	description
L2Z23_00045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z23_00055	COG1846	Transcriptional regulator
L2Z23_00060	COG1764	response to oxidative stress
L2Z23_00110	COG0037	tRNA processing
L2Z23_00120	COG0248	Ppx GppA phosphatase
L2Z23_00150	COG0072	phenylalanine-tRNA ligase activity
L2Z23_00195	COG1238	metal cluster binding
L2Z23_00200	COG0625	glutathione transferase activity
L2Z23_00215	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z23_00220	COG3028	Belongs to the UPF0307 family
L2Z23_00225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z23_00245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z23_00250	COG0617	tRNA 3'-terminal CCA addition
L2Z23_00255	COG1555	photosystem II stabilization
L2Z23_00260	COG3956	TIGRFAM MazG family protein
L2Z23_00270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z23_00290	COG0784	Response regulator, receiver
L2Z23_00290	COG2205	protein histidine kinase activity
L2Z23_00290	COG5002	protein histidine kinase activity
L2Z23_00295	COG1024	Enoyl-CoA hydratase
L2Z23_00300	COG2084	Dehydrogenase
L2Z23_00305	COG3622	Belongs to the hyi family
L2Z23_00335	COG0697	spore germination
L2Z23_00345	COG2814	Major facilitator Superfamily
L2Z23_00350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z23_00360	COG0583	DNA-binding transcription factor activity
L2Z23_00370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z23_00385	COG0084	hydrolase, TatD family'
L2Z23_00400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z23_00430	COG0440	acetolactate synthase activity
L2Z23_00435	COG0028	Belongs to the TPP enzyme family
L2Z23_00460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z23_00465	COG0577	efflux transmembrane transporter activity
L2Z23_00465	COG1136	(ABC) transporter
L2Z23_00470	COG1538	Outer membrane efflux protein
L2Z23_00485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z23_00490	COG1162	GTPase activity
L2Z23_00500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z23_00520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z23_00525	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_00565	COG2986	histidine ammonia-lyase
L2Z23_00580	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z23_00590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z23_00635	COG1426	Protein conserved in bacteria
L2Z23_00670	COG0793	Belongs to the peptidase S41A family
L2Z23_00685	COG2267	carboxylic ester hydrolase activity
L2Z23_00695	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_00700	COG3265	gluconokinase activity
L2Z23_00710	COG0800	Aldolase
L2Z23_00725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z23_00730	COG0280	phosphate acetyltransferase
L2Z23_00730	COG0857	belongs to the CobB CobQ family
L2Z23_00735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z23_00735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z23_00755	COG0740	serine-type endopeptidase activity
L2Z23_00765	COG4774	siderophore transport
L2Z23_00775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z23_00785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z23_00785	COG2813	Specifically methylates the guanine in position
L2Z23_00885	COG0788	formyltetrahydrofolate deformylase activity
L2Z23_00910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z23_00910	COG4651	solute:proton antiporter activity
L2Z23_00930	COG0724	RNA recognition motif
L2Z23_00935	COG0210	DNA helicase
L2Z23_00960	COG1733	regulation of RNA biosynthetic process
L2Z23_00970	COG2900	Belongs to the SlyX family
L2Z23_00975	COG0488	(ABC) transporter
L2Z23_00980	COG1280	lysine exporter protein (LysE YggA)
L2Z23_00985	COG1560	Kdo2-lipid A biosynthetic process
L2Z23_00995	COG1301	dicarboxylic acid transport
L2Z23_01050	COG0473	3-isopropylmalate dehydrogenase activity
L2Z23_01115	COG0583	DNA-binding transcription factor activity
L2Z23_01125	COG0625	glutathione transferase activity
L2Z23_01130	COG2378	regulation of single-species biofilm formation
L2Z23_01135	COG0546	phosphoglycolate phosphatase activity
L2Z23_01145	COG1530	ribonuclease E activity
L2Z23_01150	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z23_01165	COG0583	DNA-binding transcription factor activity
L2Z23_01170	COG4221	oxidoreductase activity
L2Z23_01175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z23_01185	COG0534	Mate efflux family protein
L2Z23_01200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z23_01240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z23_01245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z23_01260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z23_01270	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z23_01270	COG0644	oxidoreductase
L2Z23_01275	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z23_01280	COG4535	Mg2 and Co2 transporter CorC
L2Z23_01290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z23_01310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z23_01315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z23_01315	COG0475	glutathione-regulated potassium exporter activity
L2Z23_01320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z23_01330	COG0484	heat shock protein binding
L2Z23_01335	COG0789	Transcriptional regulator
L2Z23_01340	COG0598	Magnesium transport protein CorA
L2Z23_01355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z23_01360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z23_01365	COG1074	ATP-dependent DNA helicase activity
L2Z23_01370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z23_01390	COG2226	methyltransferase
L2Z23_01405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z23_01410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z23_01425	COG2111	Na H antiporter
L2Z23_01425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z23_01430	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z23_01435	COG0651	ATP synthesis coupled electron transport
L2Z23_01440	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z23_01445	COG2212	antiporter activity
L2Z23_01450	COG1320	monovalent cation:proton antiporter activity
L2Z23_01465	COG0195	Participates in both transcription termination and antitermination
L2Z23_01515	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z23_01520	COG0237	dephospho-CoA kinase activity
L2Z23_01530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z23_01545	COG0497	DNA recombination
L2Z23_01555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z23_01585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z23_01585	COG2169	Transcriptional regulator
L2Z23_01590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z23_01655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z23_01670	COG0326	Molecular chaperone. Has ATPase activity
L2Z23_01685	COG2056	Na+-H+ antiporter family
L2Z23_01690	COG0596	Alpha beta hydrolase
L2Z23_01785	COG0546	phosphoglycolate phosphatase activity
L2Z23_01790	COG1716	ATPase activity
L2Z23_01835	COG0181	hydroxymethylbilane synthase activity
L2Z23_01845	COG3275	phosphorelay sensor kinase activity
L2Z23_01865	COG1538	Outer membrane efflux protein
L2Z23_01870	COG0697	spore germination
L2Z23_01895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z23_01900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z23_01905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z23_01910	COG0772	Belongs to the SEDS family
L2Z23_01935	COG4974	Belongs to the 'phage' integrase family
L2Z23_01940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z23_01950	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z23_01960	COG2197	response regulator
L2Z23_01975	COG0793	Belongs to the peptidase S41A family
L2Z23_01980	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z23_01985	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z23_02025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z23_02025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z23_02035	COG0004	ammonium transporteR
L2Z23_02040	COG0347	Belongs to the P(II) protein family
L2Z23_02115	COG1061	Type III restriction enzyme res subunit
L2Z23_02120	COG1002	Type II restriction enzyme, methylase subunits
L2Z23_02130	COG0659	secondary active sulfate transmembrane transporter activity
L2Z23_02135	COG0589	response to stress
L2Z23_02180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z23_02200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z23_02215	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z23_02225	COG0477	Major facilitator Superfamily
L2Z23_02230	COG2860	membrane
L2Z23_02240	COG1253	flavin adenine dinucleotide binding
L2Z23_02260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z23_02300	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z23_02310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z23_02380	COG0758	DNA mediated transformation
L2Z23_02390	COG0697	spore germination
L2Z23_02395	COG1309	transcriptional regulator
L2Z23_02410	COG0386	Belongs to the glutathione peroxidase family
L2Z23_02475	COG1121	(ABC) transporter
L2Z23_02480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z23_02485	COG1280	lysine exporter protein (LysE YggA)
L2Z23_02490	COG2837	iron assimilation
L2Z23_02500	COG0281	malic enzyme
L2Z23_02545	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z23_02545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z23_02550	COG4399	Belongs to the UPF0754 family
L2Z23_02555	COG2259	Doxx family
L2Z23_02560	COG0586	Pfam SNARE associated Golgi protein
L2Z23_02575	COG1192	Involved in chromosome partitioning
L2Z23_02585	COG0271	Belongs to the BolA IbaG family
L2Z23_02605	COG2267	carboxylic ester hydrolase activity
L2Z23_02625	COG3321	synthase
L2Z23_02625	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z23_02625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z23_02625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z23_02630	COG1960	acyl-CoA dehydrogenase activity
L2Z23_02640	COG2197	response regulator
L2Z23_02650	COG3916	Acyl-homoserine-lactone synthase
L2Z23_02655	COG0477	Major facilitator Superfamily
L2Z23_02660	COG1024	Enoyl-CoA hydratase
L2Z23_02665	COG1024	Enoyl-CoA hydratase
L2Z23_02670	COG1960	acyl-CoA dehydrogenase activity
L2Z23_02675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z23_02695	COG1113	amino acid transport
L2Z23_02700	COG1113	amino acid transport
L2Z23_02705	COG0251	oxidation-reduction process
L2Z23_02745	COG0564	pseudouridine synthase activity
L2Z23_02805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z23_02820	COG1802	Transcriptional regulator
L2Z23_02825	COG1448	Aminotransferase
L2Z23_02830	COG0277	FAD linked oxidase domain protein
L2Z23_02840	COG2186	Transcriptional regulator
L2Z23_02850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z23_02855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z23_02870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z23_02880	COG0110	maltose O-acetyltransferase activity
L2Z23_02885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z23_02915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z23_02920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z23_02925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z23_02965	COG0728	peptidoglycan biosynthetic process
L2Z23_02970	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z23_03025	COG0546	phosphoglycolate phosphatase activity
L2Z23_03030	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_03050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z23_03055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z23_03060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z23_03065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z23_03070	COG1116	anion transmembrane transporter activity
L2Z23_03075	COG1309	transcriptional regulator
L2Z23_03080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z23_03090	COG0196	riboflavin kinase activity
L2Z23_03095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z23_03105	COG1047	Peptidyl-prolyl cis-trans
L2Z23_03145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z23_03150	COG0657	acetylesterase activity
L2Z23_03170	COG0583	DNA-binding transcription factor activity
L2Z23_03200	COG2951	lytic endotransglycosylase activity
L2Z23_03205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z23_03220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z23_03230	COG0671	phosphoesterase, PA-phosphatase related
L2Z23_03235	COG0861	Integral membrane protein TerC family
L2Z23_03245	COG0754	glutathionylspermidine amidase activity
L2Z23_03255	COG0402	S-adenosylhomocysteine deaminase activity
L2Z23_03270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z23_03275	COG1230	cation diffusion facilitator family transporter
L2Z23_03290	COG0706	membrane insertase activity
L2Z23_03315	COG0592	DNA-directed DNA polymerase activity
L2Z23_03325	COG0187	DNA topoisomerase II activity
L2Z23_03335	COG0586	Pfam SNARE associated Golgi protein
L2Z23_03340	COG0488	(ABC) transporter
L2Z23_03365	COG0596	Alpha beta hydrolase
L2Z23_03370	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z23_03375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z23_03415	COG0733	neurotransmitter:sodium symporter activity
L2Z23_03455	COG2233	PERMEase
L2Z23_03470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z23_03505	COG2814	Major facilitator Superfamily
L2Z23_03510	COG0656	L-ascorbic acid biosynthetic process
L2Z23_03515	COG0583	DNA-binding transcription factor activity
L2Z23_03530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z23_03535	COG1064	alcohol dehydrogenase
L2Z23_03540	COG2818	Glycosylase
L2Z23_03555	COG1194	a g-specific adenine glycosylase
L2Z23_03575	COG2983	Belongs to the UPF0260 family
L2Z23_03580	COG2133	pyrroloquinoline quinone binding
L2Z23_03585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z23_03590	COG2116	formate transmembrane transporter activity
L2Z23_03610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z23_03615	COG1335	isochorismatase
L2Z23_03620	COG0385	Bile acid
L2Z23_03625	COG0534	Mate efflux family protein
L2Z23_03630	COG1683	Conserved Protein
L2Z23_03650	COG0625	glutathione transferase activity
L2Z23_03660	COG1113	amino acid transport
L2Z23_03670	COG0523	cobalamin synthesis protein
L2Z23_03680	COG2188	Transcriptional regulator
L2Z23_03710	COG0010	Belongs to the arginase family
L2Z23_03725	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z23_03730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z23_03740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z23_03745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z23_03845	COG0534	Mate efflux family protein
L2Z23_03850	COG0436	Aminotransferase
L2Z23_03855	COG2733	membrane
L2Z23_03870	COG2918	glutathione biosynthetic process
L2Z23_03900	COG3150	esterase
L2Z23_03910	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_03915	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z23_03925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z23_03935	COG2233	PERMEase
L2Z23_03940	COG2351	hydroxyisourate hydrolase activity
L2Z23_03975	COG3706	GGDEF domain
L2Z23_03990	COG1393	Belongs to the ArsC family
L2Z23_03995	COG0708	Exodeoxyribonuclease III
L2Z23_04015	COG0189	ligase activity
L2Z23_04035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z23_04045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z23_04060	COG4942	peptidase
L2Z23_04070	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z23_04080	COG2119	membrane
L2Z23_04085	COG4774	siderophore transport
L2Z23_04090	COG0426	domain, Protein
L2Z23_04090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z23_04115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z23_04135	COG1902	pentaerythritol trinitrate reductase activity
L2Z23_04140	COG1519	Transferase
L2Z23_04145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z23_04150	COG0668	transmembrane transport
L2Z23_04160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z23_04165	COG1335	isochorismatase
L2Z23_04170	COG1522	sequence-specific DNA binding
L2Z23_04175	COG3328	transposase activity
L2Z23_04200	COG0784	Response regulator, receiver
L2Z23_04200	COG2198	Histidine kinase
L2Z23_04200	COG2205	protein histidine kinase activity
L2Z23_04205	COG3162	membrane
L2Z23_04210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z23_04220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z23_04240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z23_04245	COG1309	transcriptional regulator
L2Z23_04265	COG0351	phosphomethylpyrimidine kinase
L2Z23_04265	COG0352	thiamine-phosphate diphosphorylase activity
L2Z23_04265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z23_04275	COG2814	Major facilitator Superfamily
L2Z23_04290	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z23_04300	COG1113	amino acid transport
L2Z23_04310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z23_04315	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_04325	COG1335	isochorismatase
L2Z23_04355	COG2814	Major facilitator Superfamily
L2Z23_04360	COG0583	DNA-binding transcription factor activity
L2Z23_04380	COG0667	Aldo Keto reductase
L2Z23_04415	COG1733	regulation of RNA biosynthetic process
L2Z23_04420	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z23_04485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z23_04500	COG2329	Antibiotic biosynthesis monooxygenase
L2Z23_04530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z23_04560	COG0427	acetyl-CoA hydrolase
L2Z23_04585	COG0659	secondary active sulfate transmembrane transporter activity
L2Z23_04590	COG4221	oxidoreductase activity
L2Z23_04595	COG2873	o-acetylhomoserine
L2Z23_04600	COG0488	(ABC) transporter
L2Z23_04685	COG0833	amino acid
L2Z23_04730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z23_04735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z23_04750	COG2226	methyltransferase
L2Z23_04800	COG0067	glutamate synthase
L2Z23_04800	COG0069	glutamate synthase activity
L2Z23_04800	COG0070	glutamate synthase
L2Z23_04805	COG0493	'glutamate synthase
L2Z23_04815	COG1704	LemA family
L2Z23_04820	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z23_04840	COG3307	-O-antigen
L2Z23_04860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z23_04875	COG0194	GDP metabolic process
L2Z23_04925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z23_04945	COG5380	lipid catabolic process
L2Z23_04950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z23_04975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z23_04980	COG0277	FAD linked oxidase domain protein
L2Z23_04990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z23_04995	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z23_05010	COG1289	transmembrane transporter activity
L2Z23_05020	COG0628	permease
L2Z23_05025	COG1192	Involved in chromosome partitioning
L2Z23_05055	COG0833	amino acid
L2Z23_05060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z23_05075	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_05115	COG0583	DNA-binding transcription factor activity
L2Z23_05160	COG0517	IMP dehydrogenase activity
L2Z23_05165	COG1983	PspC domain protein
L2Z23_05175	COG1960	acyl-CoA dehydrogenase activity
L2Z23_05190	COG0408	coproporphyrinogen oxidase activity
L2Z23_05210	COG0513	Belongs to the DEAD box helicase family
L2Z23_05220	COG1127	ABC transporter
L2Z23_05225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z23_05235	COG2854	intermembrane phospholipid transfer
L2Z23_05245	COG0598	Magnesium transport protein CorA
L2Z23_05255	COG0494	nUDIX hydrolase
L2Z23_05260	COG1040	competence protein
L2Z23_05265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z23_05285	COG1946	Acyl-CoA thioesterase
L2Z23_05290	COG1301	dicarboxylic acid transport
L2Z23_05305	COG1959	2 iron, 2 sulfur cluster binding
L2Z23_05310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z23_05310	COG1017	nitric oxide dioxygenase activity
L2Z23_05315	COG0433	COG0433 Predicted ATPase
L2Z23_05320	COG0626	cystathionine gamma-synthase activity
L2Z23_05475	COG1960	acyl-CoA dehydrogenase activity
L2Z23_05480	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z23_05510	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z23_05515	COG0339	signal peptide processing
L2Z23_05520	COG0557	exoribonuclease II activity
L2Z23_05565	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z23_05570	COG2169	Transcriptional regulator
L2Z23_05575	COG0697	spore germination
L2Z23_05580	COG1295	ribonuclease BN
L2Z23_05615	COG1702	phosphate starvation-inducible protein PhoH
L2Z23_05625	COG1196	nuclear chromosome segregation
L2Z23_05625	COG0739	heme binding
L2Z23_05625	COG0741	lytic transglycosylase activity
L2Z23_05655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z23_05660	COG1183	phosphatidylcholine synthase activity
L2Z23_05705	COG1960	acyl-CoA dehydrogenase activity
L2Z23_05710	COG1309	transcriptional regulator
L2Z23_05725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z23_05730	COG1960	acyl-CoA dehydrogenase activity
L2Z23_05750	COG2969	positive regulation of protein catabolic process
L2Z23_05760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z23_05775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z23_05780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z23_05800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z23_05810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z23_05815	COG1408	metallophosphoesterase
L2Z23_05825	COG2199	diguanylate cyclase activity
L2Z23_05895	COG1607	acyl-coa hydrolase
L2Z23_05925	COG2350	Protein conserved in bacteria
L2Z23_05935	COG0613	PHP domain protein
L2Z23_05940	COG3781	membrane
L2Z23_05950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z23_05955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z23_05965	COG1862	Preprotein translocase
L2Z23_05995	COG2205	protein histidine kinase activity
L2Z23_06000	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z23_06020	COG0726	polysaccharide deacetylase
L2Z23_06025	COG0463	Glycosyl transferase, family 2
L2Z23_06030	COG0438	transferase activity, transferring glycosyl groups
L2Z23_06095	COG0625	glutathione transferase activity
L2Z23_06100	COG0583	DNA-binding transcription factor activity
L2Z23_06105	COG1960	acyl-CoA dehydrogenase activity
L2Z23_06110	COG1960	acyl-CoA dehydrogenase activity
L2Z23_06120	COG2205	protein histidine kinase activity
L2Z23_06125	COG0745	RESPONSE REGULATOR receiver
L2Z23_06130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z23_06150	COG2096	Adenosyltransferase
L2Z23_06205	COG0285	dihydrofolate synthase activity
L2Z23_06225	COG0450	alkyl hydroperoxide reductase
L2Z23_06240	COG0477	Major facilitator Superfamily
L2Z23_06245	COG1272	protein, Hemolysin III
L2Z23_06275	COG0183	Belongs to the thiolase family
L2Z23_06280	COG2207	Transcriptional regulator
L2Z23_06300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z23_06320	COG0183	Belongs to the thiolase family
L2Z23_06330	COG2885	chlorophyll binding
L2Z23_06330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z23_06340	COG1690	Belongs to the RtcB family
L2Z23_06345	COG0833	amino acid
L2Z23_06355	COG2233	PERMEase
L2Z23_06360	COG1217	gtp-binding protein TYPA
L2Z23_06385	COG2094	Belongs to the DNA glycosylase MPG family
L2Z23_06405	COG1902	pentaerythritol trinitrate reductase activity
L2Z23_06420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z23_06425	COG0354	folic acid binding
L2Z23_06435	COG3189	MarR family transcriptional regulator
L2Z23_06440	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z23_06445	COG3422	double-strand break repair
L2Z23_06485	COG0840	transmembrane signaling receptor activity
L2Z23_06505	COG5510	response to toxic substance
L2Z23_06515	COG2832	Protein of unknown function (DUF454)
L2Z23_06520	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z23_06560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z23_06570	COG1289	transmembrane transporter activity
L2Z23_06575	COG2814	Major facilitator Superfamily
L2Z23_06595	COG1115	amino acid carrier protein
L2Z23_06600	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z23_06605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z23_06610	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z23_06650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z23_06660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z23_06665	COG1077	Cell shape determining protein MreB Mrl
L2Z23_06670	COG1792	Involved in formation and maintenance of cell shape
L2Z23_06675	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z23_06680	COG0424	maF-like protein
L2Z23_06685	COG1530	ribonuclease E activity
L2Z23_06695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z23_06705	COG0560	Phosphoserine phosphatase
L2Z23_06715	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z23_06740	COG2207	Transcriptional regulator
L2Z23_06760	COG1113	amino acid transport
L2Z23_06765	COG2828	Protein conserved in bacteria
L2Z23_06770	COG0142	geranyltranstransferase activity
L2Z23_06775	COG2315	Protein conserved in bacteria
L2Z23_06790	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z23_06810	COG2194	sulfuric ester hydrolase activity
L2Z23_06815	COG0745	RESPONSE REGULATOR receiver
L2Z23_06820	COG0642	Histidine kinase
L2Z23_06830	COG0004	ammonium transporteR
L2Z23_06835	COG0583	DNA-binding transcription factor activity
L2Z23_06855	COG0525	valine-tRNA ligase activity
L2Z23_06865	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_06875	COG0393	Putative heavy-metal-binding
L2Z23_06880	COG0393	Putative heavy-metal-binding
L2Z23_06885	COG1538	Outer membrane efflux protein
L2Z23_06895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z23_06900	COG0671	phosphoesterase, PA-phosphatase related
L2Z23_06930	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z23_06945	COG1648	precorrin-2 dehydrogenase activity
L2Z23_06945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z23_06950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z23_06955	COG1733	regulation of RNA biosynthetic process
L2Z23_06965	COG0531	amino acid
L2Z23_06980	COG0321	lipoyl(octanoyl) transferase activity
L2Z23_06985	COG2921	Belongs to the UPF0250 family
L2Z23_07025	COG2009	succinate dehydrogenase
L2Z23_07030	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z23_07035	COG1053	succinate dehydrogenase
L2Z23_07040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z23_07065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z23_07085	COG2354	Protein conserved in bacteria
L2Z23_07090	COG2321	neutral zinc metallopeptidase
L2Z23_07110	COG2843	Capsule synthesis protein
L2Z23_07125	COG0589	response to stress
L2Z23_07145	COG0505	Belongs to the CarA family
L2Z23_07170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z23_07175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z23_07225	COG0477	Major facilitator Superfamily
L2Z23_07230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z23_07245	COG1597	lipid kinase activity
L2Z23_07250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z23_07280	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z23_07300	COG0741	lytic transglycosylase activity
L2Z23_07320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z23_07335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z23_07370	COG0778	Nitroreductase
L2Z23_07385	COG1929	Belongs to the glycerate kinase type-1 family
L2Z23_07390	COG0243	molybdopterin cofactor binding
L2Z23_07395	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z23_07400	COG3339	Conserved Protein
L2Z23_07410	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z23_07425	COG1113	amino acid transport
L2Z23_07435	COG0019	diaminopimelate decarboxylase activity
L2Z23_07445	COG1280	lysine exporter protein (LysE YggA)
L2Z23_07450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z23_07480	COG0463	Glycosyl transferase, family 2
L2Z23_07500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z23_07535	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z23_07540	COG1136	(ABC) transporter
L2Z23_07545	COG2333	competence protein COMEC
L2Z23_07545	COG0658	competence protein
L2Z23_07555	COG0616	signal peptide processing
L2Z23_07555	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z23_07560	COG0596	Alpha beta hydrolase
L2Z23_07565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z23_07575	COG0628	permease
L2Z23_07610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z23_07630	COG0823	Involved in the tonB-independent uptake of proteins
L2Z23_07650	COG0824	Thioesterase
L2Z23_07655	COG1473	amidohydrolase
L2Z23_07675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z23_07675	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z23_07680	COG2814	Major facilitator Superfamily
L2Z23_07690	COG1024	Enoyl-CoA hydratase
L2Z23_07695	COG1056	cytidyltransferase-related domain
L2Z23_07695	COG1051	belongs to the nudix hydrolase family
L2Z23_07705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z23_07720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z23_07735	COG4625	pathogenesis
L2Z23_07740	COG0583	DNA-binding transcription factor activity
L2Z23_07745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z23_07750	COG4208	sulfate ABC transporter
L2Z23_07755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z23_07765	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z23_07770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z23_07775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z23_07795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z23_07810	COG0681	Belongs to the peptidase S26 family
L2Z23_07825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z23_07835	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z23_07840	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z23_07850	COG4221	oxidoreductase activity
L2Z23_07880	COG0436	Aminotransferase
L2Z23_07900	COG0556	nucleotide-excision repair
L2Z23_07955	COG2070	2-Nitropropane dioxygenase
L2Z23_07985	COG1215	transferase activity, transferring glycosyl groups
L2Z23_08000	COG0415	Belongs to the DNA photolyase family
L2Z23_08010	COG1252	NADH dehydrogenase
L2Z23_08015	COG1686	Belongs to the peptidase S11 family
L2Z23_08030	COG1187	pseudouridine synthase activity
L2Z23_08055	COG0477	Major facilitator Superfamily
L2Z23_08060	COG0583	DNA-binding transcription factor activity
L2Z23_08065	COG1823	symporter activity
L2Z23_08075	COG0612	Peptidase, M16
L2Z23_08100	COG0352	thiamine-phosphate diphosphorylase activity
L2Z23_08135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z23_08150	COG1309	transcriptional regulator
L2Z23_08160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z23_08165	COG0076	glutamate decarboxylase activity
L2Z23_08175	COG1522	sequence-specific DNA binding
L2Z23_08180	COG3961	Belongs to the TPP enzyme family
L2Z23_08185	COG1113	amino acid transport
L2Z23_08190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z23_08195	COG0573	inorganic phosphate transmembrane transporter activity
L2Z23_08205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z23_08210	COG0616	signal peptide processing
L2Z23_08220	COG3328	transposase activity
L2Z23_08250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z23_08255	COG1686	Belongs to the peptidase S11 family
L2Z23_08280	COG0583	DNA-binding transcription factor activity
L2Z23_08285	COG1067	ATP-dependent peptidase activity
L2Z23_08330	COG1966	Carbon starvation protein
L2Z23_08335	COG2879	small protein
L2Z23_08370	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z23_08370	COG2508	Transcriptional regulator
L2Z23_08390	COG1113	amino acid transport
L2Z23_08395	COG0583	DNA-binding transcription factor activity
L2Z23_08400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z23_08405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z23_08415	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_08425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z23_08430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z23_08430	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z23_08465	COG2814	Major facilitator Superfamily
L2Z23_08470	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z23_08480	COG1309	transcriptional regulator
L2Z23_08500	COG1741	Belongs to the pirin family
L2Z23_08510	COG2964	Protein conserved in bacteria
L2Z23_08525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z23_08530	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z23_08535	COG4605	iron ion homeostasis
L2Z23_08540	COG4604	ABC transporter, ATP-binding protein
L2Z23_08545	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z23_08550	COG4774	siderophore transport
L2Z23_08560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z23_08565	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z23_08570	COG3433	isochorismatase activity
L2Z23_08570	COG1535	isochorismatase
L2Z23_08585	COG1132	(ABC) transporter
L2Z23_08590	COG1132	(ABC) transporter
L2Z23_08595	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z23_08605	COG1169	isochorismate synthase
L2Z23_08620	COG3739	integral membrane protein
L2Z23_08645	COG0302	gtp cyclohydrolase
L2Z23_08655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z23_08685	COG0308	aminopeptidase N
L2Z23_08690	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z23_08705	COG0174	glutamine synthetase
L2Z23_08715	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z23_08750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z23_08755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z23_08760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z23_08780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z23_08785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z23_08790	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z23_08805	COG1960	acyl-CoA dehydrogenase activity
L2Z23_08810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z23_08815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z23_08825	COG2223	nitrite transmembrane transporter activity
L2Z23_08835	COG0024	Methionine aminopeptidase
L2Z23_08840	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z23_08855	COG2207	Transcriptional regulator
L2Z23_08880	COG2951	lytic endotransglycosylase activity
L2Z23_08885	COG0772	Belongs to the SEDS family
L2Z23_08900	COG0842	Transport permease protein
L2Z23_08905	COG1131	(ABC) transporter
L2Z23_08950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z23_08965	COG4215	(ABC) transporter
L2Z23_08970	COG4160	amino acid transport
L2Z23_08975	COG4598	ABC transporter
L2Z23_08985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z23_08990	COG0826	peptidase U32
L2Z23_08995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z23_09010	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z23_09020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z23_09035	COG0642	Histidine kinase
L2Z23_09045	COG0494	nUDIX hydrolase
L2Z23_09055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z23_09060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z23_09065	COG3139	Protein of unknown function (DUF1315)
L2Z23_09070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z23_09075	COG1301	dicarboxylic acid transport
L2Z23_09080	COG1960	acyl-CoA dehydrogenase activity
L2Z23_09085	COG2819	hydrolase of the alpha beta superfamily
L2Z23_09095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z23_09105	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z23_09110	COG1234	tRNA 3'-trailer cleavage
L2Z23_09140	COG2363	Small membrane protein
L2Z23_09165	COG0513	Belongs to the DEAD box helicase family
L2Z23_09175	COG0778	Nitroreductase
L2Z23_09205	COG1286	toxin biosynthetic process
L2Z23_09230	COG4783	chaperone-mediated protein folding
L2Z23_09235	COG1610	YqeY-like protein
L2Z23_09335	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z23_09360	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z23_09365	COG0786	glutamate:sodium symporter activity
L2Z23_09375	COG2186	Transcriptional regulator
L2Z23_09425	COG0477	Major facilitator Superfamily
L2Z23_09455	COG2985	domain, Protein
L2Z23_09465	COG2995	paraquat-inducible protein a
L2Z23_09470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z23_09470	COG3008	intermembrane lipid transfer
L2Z23_09530	COG0138	bifunctional purine biosynthesis protein purh
L2Z23_09535	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z23_09565	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z23_09575	COG1305	Transglutaminase-like
L2Z23_09585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z23_09590	COG0305	Participates in initiation and elongation during chromosome replication
L2Z23_09615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z23_09625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z23_09630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z23_09655	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z23_09655	COG0726	polysaccharide deacetylase
L2Z23_09660	COG1215	transferase activity, transferring glycosyl groups
L2Z23_09665	COG3658	cytochrome
L2Z23_09675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z23_09690	COG0583	DNA-binding transcription factor activity
L2Z23_09710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z23_09715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z23_09730	COG1960	acyl-CoA dehydrogenase activity
L2Z23_09735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z23_09740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z23_09765	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z23_09770	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z23_09780	COG2205	protein histidine kinase activity
L2Z23_09785	COG0745	RESPONSE REGULATOR receiver
L2Z23_09790	COG0174	glutamine synthetase
L2Z23_09810	COG0729	surface antigen
L2Z23_09835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z23_09840	COG2814	Major facilitator Superfamily
L2Z23_09855	COG0583	DNA-binding transcription factor activity
L2Z23_09870	COG1187	pseudouridine synthase activity
L2Z23_09890	COG0802	atpase or kinase
L2Z23_09895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z23_09905	COG1923	regulation of RNA biosynthetic process
L2Z23_09910	COG0697	spore germination
L2Z23_09925	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z23_09935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z23_09940	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z23_09940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z23_09945	COG4302	ethanolamine ammonia-lyase activity
L2Z23_09950	COG4303	Ethanolamine ammonia lyase large subunit
L2Z23_09955	COG0531	amino acid
L2Z23_09975	COG1454	alcohol dehydrogenase
L2Z23_09980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z23_09990	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z23_10010	COG0308	aminopeptidase N
L2Z23_10040	COG1605	Chorismate mutase
L2Z23_10060	COG1309	transcriptional regulator
L2Z23_10070	COG0668	transmembrane transport
L2Z23_10105	COG4773	Receptor
L2Z23_10125	COG0488	(ABC) transporter
L2Z23_10130	COG0589	response to stress
L2Z23_10155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z23_10165	COG3135	benzoate transporter
L2Z23_10170	COG1522	sequence-specific DNA binding
L2Z23_10180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z23_10185	COG0583	DNA-binding transcription factor activity
L2Z23_10195	COG0183	Belongs to the thiolase family
L2Z23_10205	COG2030	dehydratase
L2Z23_10210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z23_10225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z23_10235	COG0824	Thioesterase
L2Z23_10240	COG1454	alcohol dehydrogenase
L2Z23_10250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z23_10270	COG0069	glutamate synthase activity
L2Z23_10435	COG5410	chromosome segregation
L2Z23_10555	COG0739	heme binding
L2Z23_10620	COG2814	Major facilitator Superfamily
L2Z23_10635	COG0511	ligase activity, forming carbon-carbon bonds
L2Z23_10655	COG1116	anion transmembrane transporter activity
L2Z23_10655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z23_10660	COG0745	RESPONSE REGULATOR receiver
L2Z23_10670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z23_10670	COG2146	nitrite reductase [NAD(P)H] activity
L2Z23_10675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z23_10680	COG0243	molybdopterin cofactor binding
L2Z23_10690	COG0243	molybdopterin cofactor binding
L2Z23_10695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z23_10710	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z23_10710	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z23_10715	COG0303	'Molybdopterin
L2Z23_10725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z23_10730	COG0697	spore germination
L2Z23_10750	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z23_10755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z23_10810	COG2204	response regulator
L2Z23_10815	COG3852	Histidine kinase
L2Z23_10835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z23_10840	COG0575	Belongs to the CDS family
L2Z23_10875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z23_10890	COG2137	regulation of response to DNA damage stimulus
L2Z23_10900	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z23_10905	COG1011	Hydrolase
L2Z23_10930	COG1522	sequence-specific DNA binding
L2Z23_10940	COG1113	amino acid transport
L2Z23_10960	COG0659	secondary active sulfate transmembrane transporter activity
L2Z23_10965	COG2135	peptidase activity
L2Z23_10980	COG3300	MHYT domain
L2Z23_10980	COG5001	Diguanylate cyclase
L2Z23_11000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z23_11000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z23_11000	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z23_11005	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z23_11010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z23_11010	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z23_11040	COG0024	Methionine aminopeptidase
L2Z23_11045	COG0583	DNA-binding transcription factor activity
L2Z23_11055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z23_11060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z23_11065	COG0516	GMP reductase activity
L2Z23_11065	COG0517	IMP dehydrogenase activity
L2Z23_11090	COG0552	protein localization to endoplasmic reticulum
L2Z23_11100	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z23_11115	COG4890	Cyd operon protein YbgT
L2Z23_11120	COG1294	oxidase, subunit
L2Z23_11140	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z23_11150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z23_11155	COG4774	siderophore transport
L2Z23_11170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z23_11175	COG0569	domain protein
L2Z23_11180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z23_11210	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z23_11215	COG0542	response to heat
L2Z23_11240	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z23_11240	COG1902	pentaerythritol trinitrate reductase activity
L2Z23_11285	COG2323	membrane
L2Z23_11290	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z23_11300	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z23_11305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z23_11310	COG0183	Belongs to the thiolase family
L2Z23_11315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z23_11320	COG0596	Alpha beta hydrolase
L2Z23_11325	COG2271	Major facilitator Superfamily
L2Z23_11330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z23_11335	COG3485	protocatechuate 3,4-dioxygenase
L2Z23_11340	COG3485	protocatechuate 3,4-dioxygenase
L2Z23_11345	COG0710	3-dehydroquinate dehydratase activity
L2Z23_11350	COG3420	alginic acid biosynthetic process
L2Z23_11355	COG3659	wide pore channel activity
L2Z23_11360	COG4993	Dehydrogenase
L2Z23_11370	COG2391	methyltransferase activity
L2Z23_11385	COG1414	Transcriptional regulator
L2Z23_11390	COG0583	DNA-binding transcription factor activity
L2Z23_11395	COG1960	acyl-CoA dehydrogenase activity
L2Z23_11420	COG2814	Major facilitator Superfamily
L2Z23_11430	COG0154	amidase activity
L2Z23_11450	COG4638	Rieske (2fe-2S)
L2Z23_11460	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_11470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z23_11480	COG3733	amine oxidase
L2Z23_11490	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_11500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z23_11505	COG0183	Belongs to the thiolase family
L2Z23_11510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z23_11515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z23_11525	COG4829	muconolactone delta-isomerase
L2Z23_11530	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z23_11535	COG0583	DNA-binding transcription factor activity
L2Z23_11545	COG2186	Transcriptional regulator
L2Z23_11565	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_11585	COG1960	acyl-CoA dehydrogenase activity
L2Z23_11590	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_11595	COG3829	transcription factor binding
L2Z23_11605	COG3162	membrane
L2Z23_11620	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_11635	COG0753	catalase activity
L2Z23_11655	COG1846	Transcriptional regulator
L2Z23_11660	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z23_11660	COG1902	pentaerythritol trinitrate reductase activity
L2Z23_11670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z23_11700	COG1309	transcriptional regulator
L2Z23_11710	COG1335	isochorismatase
L2Z23_11715	COG0583	DNA-binding transcription factor activity
L2Z23_11725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z23_11725	COG0475	glutathione-regulated potassium exporter activity
L2Z23_11735	COG1473	amidohydrolase
L2Z23_11745	COG2831	hemolysin activation secretion protein
L2Z23_11750	COG3210	domain, Protein
L2Z23_11780	COG2188	Transcriptional regulator
L2Z23_11795	COG0583	DNA-binding transcription factor activity
L2Z23_11825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z23_11855	COG1566	PFAM secretion protein HlyD family protein
L2Z23_11870	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_11875	COG0129	dihydroxy-acid dehydratase activity
L2Z23_11885	COG0583	DNA-binding transcription factor activity
L2Z23_11890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z23_11900	COG2084	Dehydrogenase
L2Z23_11905	COG2207	Transcriptional regulator
L2Z23_11920	COG1064	alcohol dehydrogenase
L2Z23_11930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z23_11935	COG1120	ATPase activity
L2Z23_11955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z23_12075	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z23_12125	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_12140	COG2207	Transcriptional regulator
L2Z23_12150	COG2205	protein histidine kinase activity
L2Z23_12155	COG0745	RESPONSE REGULATOR receiver
L2Z23_12160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z23_12165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z23_12170	COG1538	Outer membrane efflux protein
L2Z23_12180	COG2072	flavoprotein involved in K transport
L2Z23_12200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z23_12220	COG3539	Fimbrial protein
L2Z23_12250	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z23_12260	COG0753	catalase activity
L2Z23_12275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z23_12335	COG1535	isochorismatase
L2Z23_12335	COG3433	isochorismatase activity
L2Z23_12340	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_12345	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z23_12350	COG4149	molybdate abc transporter
L2Z23_12355	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z23_12365	COG4638	Rieske (2fe-2S)
L2Z23_12370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z23_12375	COG0543	2 iron, 2 sulfur cluster binding
L2Z23_12375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z23_12400	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_12415	COG2207	Transcriptional regulator
L2Z23_12425	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_12430	COG2610	gluconate transmembrane transporter activity
L2Z23_12440	COG0583	DNA-binding transcription factor activity
L2Z23_12450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z23_12455	COG2031	fatty acid transporter
L2Z23_12460	COG0183	Belongs to the thiolase family
L2Z23_12465	COG0583	DNA-binding transcription factor activity
L2Z23_12470	COG0583	DNA-binding transcription factor activity
L2Z23_12485	COG1027	Aspartate ammonia-lyase
L2Z23_12495	COG0477	Major facilitator Superfamily
L2Z23_12515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z23_12520	COG4521	taurine ABC transporter
L2Z23_12535	COG2188	Transcriptional regulator
L2Z23_12545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z23_12550	COG1733	regulation of RNA biosynthetic process
L2Z23_12555	COG2207	Transcriptional regulator
L2Z23_12555	COG3708	Transcriptional regulator
L2Z23_12570	COG0730	response to heat
L2Z23_12585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z23_12585	COG3453	Protein conserved in bacteria
L2Z23_12595	COG3781	membrane
L2Z23_12600	COG1063	alcohol dehydrogenase
L2Z23_12610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z23_12615	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z23_12620	COG0022	dehydrogenase e1 component
L2Z23_12625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z23_12630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z23_12645	COG3706	GGDEF domain
L2Z23_12660	COG0133	tryptophan synthase activity
L2Z23_12670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z23_12705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z23_12730	COG2226	methyltransferase
L2Z23_12785	COG0842	Transport permease protein
L2Z23_12790	COG0842	Transport permease protein
L2Z23_12795	COG1131	(ABC) transporter
L2Z23_12810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z23_12815	COG4773	Receptor
L2Z23_12835	COG0730	response to heat
L2Z23_12840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z23_12860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z23_12875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z23_12915	COG4264	IucA IucC family
L2Z23_12920	COG4264	IucA IucC family
L2Z23_12940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z23_12955	COG1960	acyl-CoA dehydrogenase activity
L2Z23_12960	COG1960	acyl-CoA dehydrogenase activity
L2Z23_12965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z23_12970	COG2207	Transcriptional regulator
L2Z23_12975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z23_12980	COG0776	regulation of translation
L2Z23_13005	COG0822	iron-sulfur transferase activity
L2Z23_13010	COG0316	Belongs to the HesB IscA family
L2Z23_13040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z23_13060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z23_13065	COG0702	epimerase
L2Z23_13100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z23_13110	COG0339	signal peptide processing
L2Z23_13180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z23_13185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z23_13215	COG0776	regulation of translation
L2Z23_13280	COG0084	hydrolase, TatD family'
L2Z23_13300	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z23_13305	COG1132	(ABC) transporter
L2Z23_13315	COG0811	peptide transport
L2Z23_13320	COG1475	DNA binding
L2Z23_13325	COG1192	Involved in chromosome partitioning
L2Z23_13335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z23_13350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z23_13355	COG0191	fructose-bisphosphate aldolase activity
L2Z23_13375	COG0424	maF-like protein
L2Z23_13380	COG2850	peptidyl-arginine hydroxylation
L2Z23_13390	COG0640	Transcriptional regulator
L2Z23_13400	COG3619	membrane
L2Z23_13405	COG3122	Protein conserved in bacteria
L2Z23_13410	COG1132	(ABC) transporter
L2Z23_13430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z23_13435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z23_13445	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z23_13445	COG0506	proline dehydrogenase activity
L2Z23_13445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z23_13450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z23_13465	COG3698	Phosphodiester glycosidase
L2Z23_13475	COG2353	YceI-like domain
L2Z23_13485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z23_13530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z23_13530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z23_13555	COG3539	Fimbrial protein
L2Z23_13560	COG3121	Chaperone
L2Z23_13585	COG0697	spore germination
L2Z23_13595	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z23_13605	COG0583	DNA-binding transcription factor activity
L2Z23_13625	COG1309	transcriptional regulator
L2Z23_13640	COG1522	sequence-specific DNA binding
L2Z23_13650	COG1126	abc transporter atp-binding protein
L2Z23_13655	COG0765	amino acid transport
L2Z23_13660	COG0765	amino acid transport
L2Z23_13690	COG1464	Belongs to the NlpA lipoprotein family
L2Z23_13700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z23_13705	COG2011	ABC-type metal ion transport system permease component
L2Z23_13710	COG0012	GTP binding
L2Z23_13735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z23_13775	COG0386	Belongs to the glutathione peroxidase family
L2Z23_13785	COG0436	Aminotransferase
L2Z23_13825	COG3634	alkyl hydroperoxide reductase activity
L2Z23_13840	COG0583	DNA-binding transcription factor activity
L2Z23_13845	COG0798	PFAM Bile acid sodium symporter
L2Z23_13850	COG0640	Transcriptional regulator
L2Z23_13865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z23_13885	COG1953	Uracil, thiamine, allantoin
L2Z23_13895	COG2175	clavaminate synthase activity
L2Z23_13900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z23_13905	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z23_13910	COG4521	taurine ABC transporter
L2Z23_13920	COG0477	Major facilitator Superfamily
L2Z23_13940	COG1271	oxidase subunit
L2Z23_13945	COG1294	oxidase, subunit
L2Z23_13955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z23_13975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z23_13995	COG3052	prosthetic group binding
L2Z23_14000	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z23_14010	COG2814	Major facilitator Superfamily
L2Z23_14030	COG1346	cytolysis
L2Z23_14040	COG0583	DNA-binding transcription factor activity
L2Z23_14045	COG0625	glutathione transferase activity
L2Z23_14050	COG0625	glutathione transferase activity
L2Z23_14055	COG0583	DNA-binding transcription factor activity
L2Z23_14070	COG1045	serine acetyltransferase
L2Z23_14075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z23_14080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z23_14090	COG1280	lysine exporter protein (LysE YggA)
L2Z23_14105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z23_14110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z23_14115	COG1126	abc transporter atp-binding protein
L2Z23_14120	COG0765	amino acid transport
L2Z23_14125	COG0765	amino acid transport
L2Z23_14145	COG0784	Response regulator, receiver
L2Z23_14145	COG2205	protein histidine kinase activity
L2Z23_14165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z23_14185	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_14235	COG0583	DNA-binding transcription factor activity
L2Z23_14255	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z23_14260	COG1309	transcriptional regulator
L2Z23_14265	COG1960	acyl-CoA dehydrogenase activity
L2Z23_14270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z23_14275	COG1024	Enoyl-CoA hydratase
L2Z23_14280	COG4770	biotin carboxylase activity
L2Z23_14290	COG0583	DNA-binding transcription factor activity
L2Z23_14305	COG1960	acyl-CoA dehydrogenase activity
L2Z23_14315	COG2814	Major facilitator Superfamily
L2Z23_14325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z23_14330	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z23_14335	COG2814	Major facilitator Superfamily
L2Z23_14340	COG1960	acyl-CoA dehydrogenase activity
L2Z23_14345	COG1024	Enoyl-CoA hydratase
L2Z23_14350	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_14355	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z23_14360	COG0183	Belongs to the thiolase family
L2Z23_14370	COG2814	Major facilitator Superfamily
L2Z23_14380	COG1024	Enoyl-CoA hydratase
L2Z23_14395	COG1960	acyl-CoA dehydrogenase activity
L2Z23_14400	COG2814	Major facilitator Superfamily
L2Z23_14405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z23_14410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z23_14425	COG3842	ATPase activity
L2Z23_14430	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z23_14440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z23_14445	COG1414	Transcriptional regulator
L2Z23_14455	COG0583	DNA-binding transcription factor activity
L2Z23_14460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z23_14465	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_14475	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z23_14485	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_14490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z23_14495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z23_14500	COG2267	carboxylic ester hydrolase activity
L2Z23_14520	COG3038	cytochrome b561
L2Z23_14525	COG0753	catalase activity
L2Z23_14555	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z23_14565	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z23_14570	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z23_14575	COG0183	Belongs to the thiolase family
L2Z23_14580	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z23_14585	COG1024	Enoyl-CoA hydratase
L2Z23_14590	COG1024	Enoyl-CoA hydratase
L2Z23_14595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z23_14600	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z23_14605	COG3396	Phenylacetate-CoA oxygenase
L2Z23_14610	COG3460	Phenylacetate-CoA oxygenase
L2Z23_14615	COG3396	Phenylacetate-CoA oxygenase
L2Z23_14620	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_14620	COG2030	dehydratase
L2Z23_14625	COG1760	l-serine dehydratase
L2Z23_14630	COG0531	amino acid
L2Z23_14635	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_14650	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z23_14660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z23_14680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z23_14690	COG0789	Transcriptional regulator
L2Z23_14705	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z23_14720	COG2807	transmembrane transport
L2Z23_14725	COG0590	tRNA wobble adenosine to inosine editing
L2Z23_14845	COG1116	anion transmembrane transporter activity
L2Z23_14850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z23_14860	COG0864	Transcriptional regulator
L2Z23_14880	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z23_14885	COG0439	Biotin carboxylase
L2Z23_14900	COG1063	alcohol dehydrogenase
L2Z23_14910	COG1309	transcriptional regulator
L2Z23_14930	COG0038	chloride channel
L2Z23_14935	COG4770	biotin carboxylase activity
L2Z23_14955	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z23_14960	COG0583	DNA-binding transcription factor activity
L2Z23_15010	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z23_15030	COG2814	Major facilitator Superfamily
L2Z23_15045	COG1560	Kdo2-lipid A biosynthetic process
L2Z23_15055	COG5006	permease, DMT superfamily
L2Z23_15060	COG1522	sequence-specific DNA binding
L2Z23_15075	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z23_15085	COG4122	O-methyltransferase activity
L2Z23_15115	COG1538	Outer membrane efflux protein
L2Z23_15120	COG1137	ATPase activity
L2Z23_15125	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z23_15135	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z23_15140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z23_15140	COG0517	IMP dehydrogenase activity
L2Z23_15175	COG2814	Major facilitator Superfamily
L2Z23_15210	COG1278	Cold shock
L2Z23_15215	COG1280	lysine exporter protein (LysE YggA)
L2Z23_15245	COG1570	exodeoxyribonuclease VII activity
L2Z23_15295	COG0583	DNA-binding transcription factor activity
L2Z23_15305	COG4638	Rieske (2fe-2S)
L2Z23_15310	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z23_15315	COG0543	2 iron, 2 sulfur cluster binding
L2Z23_15315	COG0633	Ferredoxin
L2Z23_15320	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_15325	COG3135	benzoate transporter
L2Z23_15330	COG2814	Major facilitator Superfamily
L2Z23_15345	COG1643	Atp-dependent helicase
L2Z23_15350	COG0450	alkyl hydroperoxide reductase
L2Z23_15360	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z23_15370	COG3634	alkyl hydroperoxide reductase activity
L2Z23_15390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z23_15395	COG0625	glutathione transferase activity
L2Z23_15405	COG2885	chlorophyll binding
L2Z23_15440	COG0542	response to heat
L2Z23_15455	COG1765	OsmC-like protein
L2Z23_15475	COG0667	Aldo Keto reductase
L2Z23_15490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z23_15500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z23_15510	COG0527	aspartate kinase activity
L2Z23_15520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z23_15530	COG3038	cytochrome b561
L2Z23_15535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z23_15540	COG2252	PERMEase
L2Z23_15550	COG2072	flavoprotein involved in K transport
L2Z23_15565	COG1741	Belongs to the pirin family
L2Z23_15570	COG1309	transcriptional regulator
L2Z23_15595	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2Z23_15635	COG1902	pentaerythritol trinitrate reductase activity
L2Z23_15635	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z23_15645	COG2203	Gaf domain
L2Z23_15645	COG3706	GGDEF domain
L2Z23_15645	COG4251	negative regulation of phosphorylation
L2Z23_15645	COG5001	Diguanylate cyclase
L2Z23_15655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z23_15675	COG4172	Belongs to the ABC transporter superfamily
L2Z23_15680	COG4239	(ABC) transporter, permease
L2Z23_15685	COG4174	ABC transporter (Permease)
L2Z23_15695	COG0741	lytic transglycosylase activity
L2Z23_15695	COG1388	LysM domain
L2Z23_15695	COG0741	lytic transglycosylase activity
L2Z23_15695	COG1388	LysM domain
L2Z23_15700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z23_15740	COG0583	DNA-binding transcription factor activity
L2Z23_15745	COG1279	arginine transmembrane transporter activity
L2Z23_15765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z23_15770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z23_15775	COG0006	proline dipeptidase activity
L2Z23_15815	COG2194	sulfuric ester hydrolase activity
L2Z23_16210	COG3384	dioxygenase
L2Z23_16220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z23_16225	COG2878	Part of a membrane complex involved in electron transport
L2Z23_16230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z23_16255	COG0768	penicillin binding
L2Z23_16260	COG0742	ribosomal rna small subunit methyltransferase
L2Z23_16275	COG0830	nickel cation binding
L2Z23_16285	COG0804	urea catabolic process
L2Z23_16325	COG1253	flavin adenine dinucleotide binding
L2Z23_16330	COG2851	Citrate transporter
L2Z23_16385	COG1773	rubredoxin
L2Z23_16390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z23_16400	COG0583	DNA-binding transcription factor activity
L2Z23_16425	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z23_16430	COG4181	ATPase activity
L2Z23_16475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z23_16495	COG0306	phosphate transporter
L2Z23_16505	COG3958	Transketolase
L2Z23_16510	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z23_16515	COG2271	Major facilitator Superfamily
L2Z23_16520	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_16525	COG0583	DNA-binding transcription factor activity
L2Z23_16540	COG2223	nitrite transmembrane transporter activity
L2Z23_16545	COG2207	Transcriptional regulator
L2Z23_16550	COG2066	Belongs to the glutaminase family
L2Z23_16555	COG0242	peptide deformylase activity
L2Z23_16560	COG0477	Major facilitator Superfamily
L2Z23_16570	COG0028	Belongs to the TPP enzyme family
L2Z23_16585	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_16590	COG2267	carboxylic ester hydrolase activity
L2Z23_16600	COG2271	Major facilitator Superfamily
L2Z23_16605	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z23_16615	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z23_16635	COG1414	Transcriptional regulator
L2Z23_16650	COG1024	Enoyl-CoA hydratase
L2Z23_16660	COG1215	transferase activity, transferring glycosyl groups
L2Z23_16665	COG0726	polysaccharide deacetylase
L2Z23_16665	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z23_16675	COG4681	YaeQ
L2Z23_16685	COG0523	cobalamin synthesis protein
L2Z23_16695	COG1607	acyl-coa hydrolase
L2Z23_16705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z23_16710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z23_16715	COG1309	transcriptional regulator
L2Z23_16740	COG2040	homocysteine
L2Z23_16745	COG0531	amino acid
L2Z23_16810	COG1595	DNA-templated transcription, initiation
L2Z23_16820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z23_16825	COG0477	Major facilitator Superfamily
L2Z23_16845	COG0084	hydrolase, TatD family'
L2Z23_16875	COG2826	transposase and inactivated derivatives, IS30 family
L2Z23_16895	COG0629	single-stranded DNA binding
L2Z23_16950	COG0582	viral genome integration into host DNA
L2Z23_17055	COG0592	DNA-directed DNA polymerase activity
L2Z23_17095	COG2026	Addiction module toxin, RelE StbE family
L2Z23_17290	COG1484	DNA-dependent DNA replication
L2Z23_17380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z23_17450	COG0405	Gamma-glutamyltransferase
L2Z23_17455	COG2814	Major facilitator Superfamily
L2Z23_17465	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z23_17480	COG1090	epimerase
L2Z23_17500	COG0420	3'-5' exonuclease activity
L2Z23_17525	COG0735	belongs to the Fur family
L2Z23_17530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z23_17550	COG0121	glutamine amidotransferase
L2Z23_17565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z23_17575	COG0210	DNA helicase
L2Z23_17580	COG2885	chlorophyll binding
L2Z23_17585	COG0204	Acyl-transferase
L2Z23_17600	COG2894	cell division
L2Z23_17625	COG1280	lysine exporter protein (LysE YggA)
L2Z23_17630	COG1674	ftsk spoiiie
L2Z23_17630	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z23_17635	COG0492	ferredoxin-NADP+ reductase activity
L2Z23_17640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z23_17650	COG0456	acetyltransferase
L2Z23_17695	COG1981	membrane
L2Z23_17710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z23_17710	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z23_17730	COG1012	belongs to the aldehyde dehydrogenase family
L2Z23_17740	COG0657	acetylesterase activity
L2Z23_17750	COG0473	3-isopropylmalate dehydrogenase activity
L2Z23_17755	COG0583	DNA-binding transcription factor activity
L2Z23_17775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z23_17800	COG0564	pseudouridine synthase activity
L2Z23_17810	COG0358	DNA primase activity
L2Z23_17825	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z23_17855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z23_17885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z23_17895	COG0351	phosphomethylpyrimidine kinase
L2Z23_17895	COG0352	thiamine-phosphate diphosphorylase activity
L2Z23_17895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z23_17900	COG1652	LysM domain
L2Z23_17930	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z23_17935	COG3101	peptidyl-lysine hydroxylation
L2Z23_17940	COG0009	L-threonylcarbamoyladenylate synthase
L2Z23_17945	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z23_17950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z23_17965	COG4106	trans-aconitate 2-methyltransferase activity
L2Z23_17980	COG2226	methyltransferase
L2Z23_17980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z23_17980	COG0596	Alpha beta hydrolase
L2Z23_17985	COG1877	trehalose-phosphatase activity
L2Z23_17990	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z23_17995	COG2223	nitrite transmembrane transporter activity
L2Z23_18015	COG1196	nuclear chromosome segregation
L2Z23_18025	COG0730	response to heat
L2Z23_18040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z23_18050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z23_18100	COG0489	protein tyrosine kinase activity
L2Z23_18110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z23_18110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z23_18140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z23_18145	COG2081	HI0933 family
L2Z23_18155	COG0668	transmembrane transport
L2Z23_18175	COG0583	DNA-binding transcription factor activity
L2Z23_18195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z23_18200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z23_18230	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z23_18270	COG0745	RESPONSE REGULATOR receiver
L2Z23_18290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z23_18300	COG2205	protein histidine kinase activity
L2Z23_18365	COG4993	Dehydrogenase
L2Z23_18390	COG0384	phenazine biosynthesis protein PhzF
L2Z23_18415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z23_18430	COG0583	DNA-binding transcription factor activity
L2Z23_18460	COG0583	DNA-binding transcription factor activity
L2Z23_18475	COG0583	DNA-binding transcription factor activity
L2Z23_18480	COG1053	succinate dehydrogenase
L2Z23_18490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z23_18495	COG2814	Major facilitator Superfamily
L2Z23_18500	COG1960	acyl-CoA dehydrogenase activity
L2Z23_18505	COG0583	DNA-binding transcription factor activity
L2Z23_18510	COG1063	alcohol dehydrogenase
L2Z23_18540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z23_18545	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z23_18550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z23_18565	COG3667	copper resistance
L2Z23_18570	COG2132	Multicopper oxidase
L2Z23_18580	COG0561	phosphatase activity
L2Z23_18585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z23_18610	COG1214	PFAM Peptidase M22, glycoprotease
L2Z23_18670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z23_18675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z23_18680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine