locus-tag	class	description
L2Z24_00055	COG1607	acyl-coa hydrolase
L2Z24_00085	COG2350	Protein conserved in bacteria
L2Z24_00095	COG0613	PHP domain protein
L2Z24_00100	COG3781	membrane
L2Z24_00110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z24_00115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z24_00125	COG1862	Preprotein translocase
L2Z24_00175	COG2205	protein histidine kinase activity
L2Z24_00180	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z24_00200	COG0726	polysaccharide deacetylase
L2Z24_00205	COG0463	Glycosyl transferase, family 2
L2Z24_00210	COG0438	transferase activity, transferring glycosyl groups
L2Z24_00275	COG0625	glutathione transferase activity
L2Z24_00280	COG0583	DNA-binding transcription factor activity
L2Z24_00285	COG1960	acyl-CoA dehydrogenase activity
L2Z24_00290	COG1960	acyl-CoA dehydrogenase activity
L2Z24_00300	COG2205	protein histidine kinase activity
L2Z24_00305	COG0745	RESPONSE REGULATOR receiver
L2Z24_00310	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z24_00330	COG2096	Adenosyltransferase
L2Z24_00380	COG0285	dihydrofolate synthase activity
L2Z24_00400	COG0450	alkyl hydroperoxide reductase
L2Z24_00415	COG0477	Major facilitator Superfamily
L2Z24_00420	COG1272	protein, Hemolysin III
L2Z24_00450	COG0183	Belongs to the thiolase family
L2Z24_00455	COG2207	Transcriptional regulator
L2Z24_00475	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z24_00500	COG0183	Belongs to the thiolase family
L2Z24_00510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z24_00510	COG2885	chlorophyll binding
L2Z24_00520	COG1690	Belongs to the RtcB family
L2Z24_00525	COG0833	amino acid
L2Z24_00535	COG2233	PERMEase
L2Z24_00540	COG1217	gtp-binding protein TYPA
L2Z24_00565	COG2094	Belongs to the DNA glycosylase MPG family
L2Z24_00570	COG4772	TonB-dependent receptor
L2Z24_00575	COG1902	pentaerythritol trinitrate reductase activity
L2Z24_00590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z24_00595	COG0354	folic acid binding
L2Z24_00605	COG3189	MarR family transcriptional regulator
L2Z24_00610	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z24_00615	COG3422	double-strand break repair
L2Z24_00655	COG0840	transmembrane signaling receptor activity
L2Z24_00675	COG5510	response to toxic substance
L2Z24_00685	COG2832	Protein of unknown function (DUF454)
L2Z24_00690	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z24_00730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z24_00740	COG1289	transmembrane transporter activity
L2Z24_00745	COG2814	Major facilitator Superfamily
L2Z24_00765	COG1115	amino acid carrier protein
L2Z24_00770	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z24_00775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z24_00780	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z24_00810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z24_00820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z24_00825	COG1077	Cell shape determining protein MreB Mrl
L2Z24_00830	COG1792	Involved in formation and maintenance of cell shape
L2Z24_00835	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z24_00840	COG0424	maF-like protein
L2Z24_00845	COG1530	ribonuclease E activity
L2Z24_00855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z24_00865	COG0560	Phosphoserine phosphatase
L2Z24_00875	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z24_00900	COG2207	Transcriptional regulator
L2Z24_00920	COG1113	amino acid transport
L2Z24_00925	COG2828	Protein conserved in bacteria
L2Z24_00930	COG0142	geranyltranstransferase activity
L2Z24_00935	COG2315	Protein conserved in bacteria
L2Z24_00950	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z24_00970	COG2194	sulfuric ester hydrolase activity
L2Z24_00975	COG0745	RESPONSE REGULATOR receiver
L2Z24_00980	COG0642	Histidine kinase
L2Z24_00990	COG0004	ammonium transporteR
L2Z24_00995	COG0583	DNA-binding transcription factor activity
L2Z24_01015	COG0525	valine-tRNA ligase activity
L2Z24_01025	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_01035	COG0393	Putative heavy-metal-binding
L2Z24_01040	COG0393	Putative heavy-metal-binding
L2Z24_01045	COG1538	Outer membrane efflux protein
L2Z24_01055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z24_01060	COG0671	phosphoesterase, PA-phosphatase related
L2Z24_01090	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z24_01105	COG1648	precorrin-2 dehydrogenase activity
L2Z24_01105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z24_01110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z24_01115	COG1733	regulation of RNA biosynthetic process
L2Z24_01125	COG0531	amino acid
L2Z24_01140	COG0321	lipoyl(octanoyl) transferase activity
L2Z24_01145	COG2921	Belongs to the UPF0250 family
L2Z24_01190	COG2009	succinate dehydrogenase
L2Z24_01195	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z24_01200	COG1053	succinate dehydrogenase
L2Z24_01205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z24_01230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z24_01250	COG2354	Protein conserved in bacteria
L2Z24_01255	COG2321	neutral zinc metallopeptidase
L2Z24_01275	COG2843	Capsule synthesis protein
L2Z24_01290	COG0589	response to stress
L2Z24_01310	COG0505	Belongs to the CarA family
L2Z24_01335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z24_01340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z24_01390	COG0477	Major facilitator Superfamily
L2Z24_01395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z24_01410	COG1597	lipid kinase activity
L2Z24_01415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z24_01440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z24_01445	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z24_01465	COG0741	lytic transglycosylase activity
L2Z24_01485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z24_01500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z24_01530	COG0778	Nitroreductase
L2Z24_01545	COG1929	Belongs to the glycerate kinase type-1 family
L2Z24_01550	COG0243	molybdopterin cofactor binding
L2Z24_01555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z24_01560	COG3339	Conserved Protein
L2Z24_01570	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z24_01585	COG1113	amino acid transport
L2Z24_01595	COG0019	diaminopimelate decarboxylase activity
L2Z24_01605	COG1280	lysine exporter protein (LysE YggA)
L2Z24_01610	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z24_01640	COG0463	Glycosyl transferase, family 2
L2Z24_01660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z24_01695	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z24_01700	COG1136	(ABC) transporter
L2Z24_01705	COG2333	competence protein COMEC
L2Z24_01705	COG0658	competence protein
L2Z24_01715	COG0616	signal peptide processing
L2Z24_01715	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z24_01720	COG0596	Alpha beta hydrolase
L2Z24_01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z24_01735	COG0628	permease
L2Z24_01770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z24_01790	COG0823	Involved in the tonB-independent uptake of proteins
L2Z24_01810	COG0824	Thioesterase
L2Z24_01815	COG1473	amidohydrolase
L2Z24_01835	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z24_01835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z24_01840	COG2814	Major facilitator Superfamily
L2Z24_01850	COG1024	Enoyl-CoA hydratase
L2Z24_01855	COG1051	belongs to the nudix hydrolase family
L2Z24_01855	COG1056	cytidyltransferase-related domain
L2Z24_01865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z24_01880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z24_01895	COG4625	pathogenesis
L2Z24_01900	COG0583	DNA-binding transcription factor activity
L2Z24_01905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z24_01910	COG4208	sulfate ABC transporter
L2Z24_01915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z24_01925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z24_01930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z24_01935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z24_01955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z24_01970	COG0681	Belongs to the peptidase S26 family
L2Z24_01985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z24_01995	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z24_02000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z24_02010	COG4221	oxidoreductase activity
L2Z24_02040	COG0436	Aminotransferase
L2Z24_02060	COG0556	nucleotide-excision repair
L2Z24_02115	COG2070	2-Nitropropane dioxygenase
L2Z24_02145	COG1215	transferase activity, transferring glycosyl groups
L2Z24_02160	COG0415	Belongs to the DNA photolyase family
L2Z24_02170	COG1252	NADH dehydrogenase
L2Z24_02175	COG1686	Belongs to the peptidase S11 family
L2Z24_02190	COG1187	pseudouridine synthase activity
L2Z24_02215	COG0477	Major facilitator Superfamily
L2Z24_02220	COG0583	DNA-binding transcription factor activity
L2Z24_02225	COG1823	symporter activity
L2Z24_02235	COG0612	Peptidase, M16
L2Z24_02260	COG0352	thiamine-phosphate diphosphorylase activity
L2Z24_02295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z24_02310	COG1309	transcriptional regulator
L2Z24_02320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z24_02325	COG0076	glutamate decarboxylase activity
L2Z24_02335	COG1522	sequence-specific DNA binding
L2Z24_02340	COG3961	Belongs to the TPP enzyme family
L2Z24_02345	COG1113	amino acid transport
L2Z24_02350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z24_02355	COG0573	inorganic phosphate transmembrane transporter activity
L2Z24_02365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z24_02370	COG0616	signal peptide processing
L2Z24_02405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z24_02410	COG1686	Belongs to the peptidase S11 family
L2Z24_02435	COG0583	DNA-binding transcription factor activity
L2Z24_02440	COG1067	ATP-dependent peptidase activity
L2Z24_02485	COG1966	Carbon starvation protein
L2Z24_02490	COG2879	small protein
L2Z24_02525	COG2508	Transcriptional regulator
L2Z24_02525	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z24_02545	COG1113	amino acid transport
L2Z24_02550	COG0583	DNA-binding transcription factor activity
L2Z24_02555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z24_02560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z24_02570	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_02580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z24_02585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z24_02585	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z24_02620	COG2814	Major facilitator Superfamily
L2Z24_02625	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z24_02635	COG1309	transcriptional regulator
L2Z24_02655	COG1741	Belongs to the pirin family
L2Z24_02665	COG2964	Protein conserved in bacteria
L2Z24_02680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z24_02685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z24_02690	COG4605	iron ion homeostasis
L2Z24_02695	COG4604	ABC transporter, ATP-binding protein
L2Z24_02700	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z24_02705	COG4774	siderophore transport
L2Z24_02715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z24_02720	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z24_02725	COG3433	isochorismatase activity
L2Z24_02725	COG1535	isochorismatase
L2Z24_02735	COG1132	(ABC) transporter
L2Z24_02740	COG1132	(ABC) transporter
L2Z24_02745	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z24_02755	COG1169	isochorismate synthase
L2Z24_02770	COG3739	integral membrane protein
L2Z24_02795	COG0302	gtp cyclohydrolase
L2Z24_02860	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z24_02875	COG0174	glutamine synthetase
L2Z24_02885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z24_02920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z24_02925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z24_02930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z24_02950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z24_02955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z24_02960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z24_02975	COG1960	acyl-CoA dehydrogenase activity
L2Z24_02980	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z24_02985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z24_02995	COG2223	nitrite transmembrane transporter activity
L2Z24_03005	COG0024	Methionine aminopeptidase
L2Z24_03010	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z24_03025	COG2207	Transcriptional regulator
L2Z24_03050	COG2951	lytic endotransglycosylase activity
L2Z24_03055	COG0772	Belongs to the SEDS family
L2Z24_03070	COG0842	Transport permease protein
L2Z24_03075	COG1131	(ABC) transporter
L2Z24_03120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z24_03135	COG4215	(ABC) transporter
L2Z24_03140	COG4160	amino acid transport
L2Z24_03145	COG4598	ABC transporter
L2Z24_03155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z24_03160	COG0826	peptidase U32
L2Z24_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z24_03180	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z24_03190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z24_03205	COG0642	Histidine kinase
L2Z24_03215	COG0494	nUDIX hydrolase
L2Z24_03225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z24_03230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z24_03235	COG3139	Protein of unknown function (DUF1315)
L2Z24_03240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z24_03245	COG1301	dicarboxylic acid transport
L2Z24_03250	COG1960	acyl-CoA dehydrogenase activity
L2Z24_03255	COG2819	hydrolase of the alpha beta superfamily
L2Z24_03265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z24_03275	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z24_03280	COG1234	tRNA 3'-trailer cleavage
L2Z24_03315	COG2363	Small membrane protein
L2Z24_03340	COG0513	Belongs to the DEAD box helicase family
L2Z24_03350	COG0778	Nitroreductase
L2Z24_03380	COG1286	toxin biosynthetic process
L2Z24_03405	COG4783	chaperone-mediated protein folding
L2Z24_03410	COG1610	YqeY-like protein
L2Z24_03510	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z24_03535	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z24_03540	COG0786	glutamate:sodium symporter activity
L2Z24_03550	COG2186	Transcriptional regulator
L2Z24_03600	COG0477	Major facilitator Superfamily
L2Z24_03630	COG2985	domain, Protein
L2Z24_03645	COG2995	paraquat-inducible protein a
L2Z24_03650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z24_03650	COG3008	intermembrane lipid transfer
L2Z24_03660	COG1794	racemase activity, acting on amino acids and derivatives
L2Z24_03690	COG1301	dicarboxylic acid transport
L2Z24_03700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z24_03705	COG2011	ABC-type metal ion transport system permease component
L2Z24_03710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z24_03715	COG1464	Belongs to the NlpA lipoprotein family
L2Z24_03720	COG0151	Belongs to the GarS family
L2Z24_03725	COG0138	bifunctional purine biosynthesis protein purh
L2Z24_03730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z24_03760	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z24_03770	COG1305	Transglutaminase-like
L2Z24_03780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z24_03785	COG0305	Participates in initiation and elongation during chromosome replication
L2Z24_03810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z24_03820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z24_03825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z24_03850	COG0726	polysaccharide deacetylase
L2Z24_03850	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z24_03855	COG1215	transferase activity, transferring glycosyl groups
L2Z24_03860	COG3658	cytochrome
L2Z24_03870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z24_03885	COG0583	DNA-binding transcription factor activity
L2Z24_03905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z24_03910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z24_03925	COG1960	acyl-CoA dehydrogenase activity
L2Z24_03935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z24_03960	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z24_03965	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z24_03975	COG2205	protein histidine kinase activity
L2Z24_03980	COG0745	RESPONSE REGULATOR receiver
L2Z24_03985	COG0174	glutamine synthetase
L2Z24_04005	COG0729	surface antigen
L2Z24_04030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z24_04035	COG2814	Major facilitator Superfamily
L2Z24_04050	COG0583	DNA-binding transcription factor activity
L2Z24_04065	COG1187	pseudouridine synthase activity
L2Z24_04085	COG0802	atpase or kinase
L2Z24_04090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z24_04100	COG1923	regulation of RNA biosynthetic process
L2Z24_04105	COG0697	spore germination
L2Z24_04120	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z24_04130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z24_04135	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z24_04135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z24_04140	COG4302	ethanolamine ammonia-lyase activity
L2Z24_04145	COG4303	Ethanolamine ammonia lyase large subunit
L2Z24_04150	COG0531	amino acid
L2Z24_04170	COG1454	alcohol dehydrogenase
L2Z24_04175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z24_04185	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z24_04205	COG0308	aminopeptidase N
L2Z24_04215	COG4221	oxidoreductase activity
L2Z24_04225	COG1605	Chorismate mutase
L2Z24_04245	COG1309	transcriptional regulator
L2Z24_04255	COG0668	transmembrane transport
L2Z24_04285	COG4773	Receptor
L2Z24_04305	COG0488	(ABC) transporter
L2Z24_04310	COG0589	response to stress
L2Z24_04335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z24_04345	COG3135	benzoate transporter
L2Z24_04350	COG1522	sequence-specific DNA binding
L2Z24_04360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z24_04365	COG0583	DNA-binding transcription factor activity
L2Z24_04375	COG0183	Belongs to the thiolase family
L2Z24_04385	COG2030	dehydratase
L2Z24_04390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z24_04405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z24_04415	COG0824	Thioesterase
L2Z24_04420	COG1454	alcohol dehydrogenase
L2Z24_04430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z24_04450	COG0069	glutamate synthase activity
L2Z24_04470	COG2814	Major facilitator Superfamily
L2Z24_04485	COG0511	ligase activity, forming carbon-carbon bonds
L2Z24_04505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z24_04505	COG1116	anion transmembrane transporter activity
L2Z24_04510	COG0745	RESPONSE REGULATOR receiver
L2Z24_04520	COG2146	nitrite reductase [NAD(P)H] activity
L2Z24_04520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z24_04525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z24_04530	COG0243	molybdopterin cofactor binding
L2Z24_04540	COG0243	molybdopterin cofactor binding
L2Z24_04545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z24_04560	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z24_04560	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z24_04565	COG0303	'Molybdopterin
L2Z24_04575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z24_04580	COG0697	spore germination
L2Z24_04600	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z24_04605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z24_04665	COG2204	response regulator
L2Z24_04670	COG3852	Histidine kinase
L2Z24_04690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z24_04695	COG0575	Belongs to the CDS family
L2Z24_04730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z24_04745	COG2137	regulation of response to DNA damage stimulus
L2Z24_04755	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z24_04760	COG1011	Hydrolase
L2Z24_04785	COG1522	sequence-specific DNA binding
L2Z24_04795	COG1113	amino acid transport
L2Z24_04815	COG0659	secondary active sulfate transmembrane transporter activity
L2Z24_04820	COG2135	peptidase activity
L2Z24_04840	COG5001	Diguanylate cyclase
L2Z24_04840	COG3300	MHYT domain
L2Z24_04860	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z24_04860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z24_04860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z24_04865	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z24_04870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z24_04870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z24_04900	COG0024	Methionine aminopeptidase
L2Z24_04905	COG0583	DNA-binding transcription factor activity
L2Z24_04915	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z24_04920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z24_04925	COG0517	IMP dehydrogenase activity
L2Z24_04925	COG0516	GMP reductase activity
L2Z24_04950	COG0552	protein localization to endoplasmic reticulum
L2Z24_04960	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z24_04975	COG4890	Cyd operon protein YbgT
L2Z24_04980	COG1294	oxidase, subunit
L2Z24_05000	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z24_05010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z24_05015	COG4774	siderophore transport
L2Z24_05030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z24_05035	COG0569	domain protein
L2Z24_05040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z24_05070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z24_05075	COG0542	response to heat
L2Z24_05100	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z24_05100	COG1902	pentaerythritol trinitrate reductase activity
L2Z24_05145	COG2323	membrane
L2Z24_05150	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z24_05160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z24_05165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z24_05170	COG0183	Belongs to the thiolase family
L2Z24_05175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z24_05180	COG0596	Alpha beta hydrolase
L2Z24_05185	COG2271	Major facilitator Superfamily
L2Z24_05190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z24_05195	COG3485	protocatechuate 3,4-dioxygenase
L2Z24_05200	COG3485	protocatechuate 3,4-dioxygenase
L2Z24_05205	COG0710	3-dehydroquinate dehydratase activity
L2Z24_05210	COG3420	alginic acid biosynthetic process
L2Z24_05215	COG3659	wide pore channel activity
L2Z24_05220	COG4993	Dehydrogenase
L2Z24_05230	COG2391	methyltransferase activity
L2Z24_05245	COG1414	Transcriptional regulator
L2Z24_05250	COG0583	DNA-binding transcription factor activity
L2Z24_05255	COG1960	acyl-CoA dehydrogenase activity
L2Z24_05280	COG2814	Major facilitator Superfamily
L2Z24_05290	COG0154	amidase activity
L2Z24_05310	COG4638	Rieske (2fe-2S)
L2Z24_05320	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_05330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z24_05340	COG3733	amine oxidase
L2Z24_05350	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_05360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z24_05365	COG0183	Belongs to the thiolase family
L2Z24_05370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z24_05375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z24_05385	COG4829	muconolactone delta-isomerase
L2Z24_05390	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z24_05395	COG0583	DNA-binding transcription factor activity
L2Z24_05405	COG2186	Transcriptional regulator
L2Z24_05425	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_05445	COG1960	acyl-CoA dehydrogenase activity
L2Z24_05450	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_05455	COG3829	transcription factor binding
L2Z24_05465	COG3162	membrane
L2Z24_05480	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_05495	COG0753	catalase activity
L2Z24_05515	COG1846	Transcriptional regulator
L2Z24_05520	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z24_05520	COG1902	pentaerythritol trinitrate reductase activity
L2Z24_05530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z24_05560	COG1309	transcriptional regulator
L2Z24_05570	COG1335	isochorismatase
L2Z24_05575	COG0583	DNA-binding transcription factor activity
L2Z24_05585	COG0475	glutathione-regulated potassium exporter activity
L2Z24_05585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z24_05595	COG1473	amidohydrolase
L2Z24_05605	COG2831	hemolysin activation secretion protein
L2Z24_05610	COG3210	domain, Protein
L2Z24_05640	COG2188	Transcriptional regulator
L2Z24_05655	COG0583	DNA-binding transcription factor activity
L2Z24_05685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z24_05715	COG1566	PFAM secretion protein HlyD family protein
L2Z24_05730	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_05735	COG0129	dihydroxy-acid dehydratase activity
L2Z24_05745	COG0583	DNA-binding transcription factor activity
L2Z24_05750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z24_05760	COG2084	Dehydrogenase
L2Z24_05765	COG2207	Transcriptional regulator
L2Z24_05780	COG1064	alcohol dehydrogenase
L2Z24_05790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z24_05795	COG1120	ATPase activity
L2Z24_05825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z24_05945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z24_05995	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_06010	COG2207	Transcriptional regulator
L2Z24_06020	COG2205	protein histidine kinase activity
L2Z24_06025	COG0745	RESPONSE REGULATOR receiver
L2Z24_06030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z24_06035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z24_06040	COG1538	Outer membrane efflux protein
L2Z24_06050	COG2072	flavoprotein involved in K transport
L2Z24_06075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z24_06095	COG3539	Fimbrial protein
L2Z24_06125	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z24_06135	COG0753	catalase activity
L2Z24_06150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z24_06210	COG1535	isochorismatase
L2Z24_06210	COG3433	isochorismatase activity
L2Z24_06215	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_06220	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z24_06225	COG4149	molybdate abc transporter
L2Z24_06230	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z24_06240	COG4638	Rieske (2fe-2S)
L2Z24_06245	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z24_06250	COG0543	2 iron, 2 sulfur cluster binding
L2Z24_06250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z24_06275	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_06290	COG2207	Transcriptional regulator
L2Z24_06300	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_06305	COG2610	gluconate transmembrane transporter activity
L2Z24_06315	COG0583	DNA-binding transcription factor activity
L2Z24_06325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z24_06330	COG2031	fatty acid transporter
L2Z24_06335	COG0183	Belongs to the thiolase family
L2Z24_06340	COG0583	DNA-binding transcription factor activity
L2Z24_06345	COG0583	DNA-binding transcription factor activity
L2Z24_06360	COG1027	Aspartate ammonia-lyase
L2Z24_06370	COG0477	Major facilitator Superfamily
L2Z24_06390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z24_06395	COG4521	taurine ABC transporter
L2Z24_06410	COG2188	Transcriptional regulator
L2Z24_06420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z24_06425	COG1733	regulation of RNA biosynthetic process
L2Z24_06430	COG2207	Transcriptional regulator
L2Z24_06430	COG3708	Transcriptional regulator
L2Z24_06445	COG0730	response to heat
L2Z24_06460	COG3453	Protein conserved in bacteria
L2Z24_06460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z24_06470	COG3781	membrane
L2Z24_06475	COG1063	alcohol dehydrogenase
L2Z24_06485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z24_06490	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z24_06495	COG0022	dehydrogenase e1 component
L2Z24_06500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z24_06505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z24_06525	COG3706	GGDEF domain
L2Z24_06540	COG0133	tryptophan synthase activity
L2Z24_06550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z24_06585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z24_06610	COG2226	methyltransferase
L2Z24_06665	COG0842	Transport permease protein
L2Z24_06670	COG0842	Transport permease protein
L2Z24_06675	COG1131	(ABC) transporter
L2Z24_06690	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z24_06695	COG4773	Receptor
L2Z24_06715	COG0730	response to heat
L2Z24_06720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z24_06740	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z24_06755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z24_06795	COG4264	IucA IucC family
L2Z24_06800	COG4264	IucA IucC family
L2Z24_06820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z24_06835	COG1960	acyl-CoA dehydrogenase activity
L2Z24_06840	COG1960	acyl-CoA dehydrogenase activity
L2Z24_06845	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z24_06850	COG2207	Transcriptional regulator
L2Z24_06855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z24_06860	COG0776	regulation of translation
L2Z24_06885	COG0822	iron-sulfur transferase activity
L2Z24_06890	COG0316	Belongs to the HesB IscA family
L2Z24_06920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z24_06940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z24_06945	COG0702	epimerase
L2Z24_06985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z24_06995	COG0339	signal peptide processing
L2Z24_07045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z24_07050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z24_07070	COG2826	transposase and inactivated derivatives, IS30 family
L2Z24_07090	COG0776	regulation of translation
L2Z24_07155	COG0084	hydrolase, TatD family'
L2Z24_07175	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z24_07180	COG1132	(ABC) transporter
L2Z24_07190	COG0811	peptide transport
L2Z24_07195	COG1475	DNA binding
L2Z24_07200	COG1192	Involved in chromosome partitioning
L2Z24_07210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z24_07225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z24_07230	COG0191	fructose-bisphosphate aldolase activity
L2Z24_07250	COG0424	maF-like protein
L2Z24_07255	COG2850	peptidyl-arginine hydroxylation
L2Z24_07265	COG0640	Transcriptional regulator
L2Z24_07275	COG3619	membrane
L2Z24_07280	COG3122	Protein conserved in bacteria
L2Z24_07285	COG1132	(ABC) transporter
L2Z24_07305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z24_07310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z24_07320	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z24_07320	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z24_07320	COG0506	proline dehydrogenase activity
L2Z24_07325	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z24_07340	COG3698	Phosphodiester glycosidase
L2Z24_07350	COG2353	YceI-like domain
L2Z24_07360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z24_07405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z24_07405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z24_07430	COG3539	Fimbrial protein
L2Z24_07435	COG3121	Chaperone
L2Z24_07455	COG0697	spore germination
L2Z24_07465	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z24_07475	COG0583	DNA-binding transcription factor activity
L2Z24_07495	COG1309	transcriptional regulator
L2Z24_07510	COG1522	sequence-specific DNA binding
L2Z24_07520	COG1126	abc transporter atp-binding protein
L2Z24_07525	COG0765	amino acid transport
L2Z24_07530	COG0765	amino acid transport
L2Z24_07560	COG1464	Belongs to the NlpA lipoprotein family
L2Z24_07570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z24_07575	COG2011	ABC-type metal ion transport system permease component
L2Z24_07580	COG0012	GTP binding
L2Z24_07605	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z24_07645	COG0386	Belongs to the glutathione peroxidase family
L2Z24_07655	COG0436	Aminotransferase
L2Z24_07695	COG3634	alkyl hydroperoxide reductase activity
L2Z24_07710	COG0583	DNA-binding transcription factor activity
L2Z24_07715	COG0798	PFAM Bile acid sodium symporter
L2Z24_07720	COG0640	Transcriptional regulator
L2Z24_07735	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z24_07745	COG0583	DNA-binding transcription factor activity
L2Z24_07755	COG1953	Uracil, thiamine, allantoin
L2Z24_07765	COG2175	clavaminate synthase activity
L2Z24_07770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z24_07775	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z24_07780	COG4521	taurine ABC transporter
L2Z24_07790	COG0477	Major facilitator Superfamily
L2Z24_07810	COG1271	oxidase subunit
L2Z24_07815	COG1294	oxidase, subunit
L2Z24_07825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z24_07845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z24_07865	COG3052	prosthetic group binding
L2Z24_07870	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z24_07880	COG3293	Transposase
L2Z24_07885	COG2814	Major facilitator Superfamily
L2Z24_07905	COG1346	cytolysis
L2Z24_07915	COG0583	DNA-binding transcription factor activity
L2Z24_07920	COG0625	glutathione transferase activity
L2Z24_07925	COG0625	glutathione transferase activity
L2Z24_07930	COG0583	DNA-binding transcription factor activity
L2Z24_07945	COG1045	serine acetyltransferase
L2Z24_07950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z24_07955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z24_07965	COG1280	lysine exporter protein (LysE YggA)
L2Z24_07980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z24_07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z24_07990	COG1126	abc transporter atp-binding protein
L2Z24_07995	COG0765	amino acid transport
L2Z24_08000	COG0765	amino acid transport
L2Z24_08020	COG2205	protein histidine kinase activity
L2Z24_08020	COG0784	Response regulator, receiver
L2Z24_08040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z24_08060	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_08110	COG0583	DNA-binding transcription factor activity
L2Z24_08130	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z24_08135	COG1309	transcriptional regulator
L2Z24_08140	COG1960	acyl-CoA dehydrogenase activity
L2Z24_08145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z24_08150	COG1024	Enoyl-CoA hydratase
L2Z24_08155	COG4770	biotin carboxylase activity
L2Z24_08165	COG0583	DNA-binding transcription factor activity
L2Z24_08180	COG1960	acyl-CoA dehydrogenase activity
L2Z24_08190	COG2814	Major facilitator Superfamily
L2Z24_08200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z24_08205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z24_08210	COG2814	Major facilitator Superfamily
L2Z24_08215	COG1960	acyl-CoA dehydrogenase activity
L2Z24_08220	COG1024	Enoyl-CoA hydratase
L2Z24_08225	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_08230	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z24_08235	COG0183	Belongs to the thiolase family
L2Z24_08245	COG2814	Major facilitator Superfamily
L2Z24_08255	COG1024	Enoyl-CoA hydratase
L2Z24_08270	COG1960	acyl-CoA dehydrogenase activity
L2Z24_08275	COG2814	Major facilitator Superfamily
L2Z24_08280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z24_08285	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z24_08300	COG3842	ATPase activity
L2Z24_08305	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z24_08315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z24_08320	COG1414	Transcriptional regulator
L2Z24_08330	COG0583	DNA-binding transcription factor activity
L2Z24_08335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z24_08340	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_08350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z24_08360	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_08365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z24_08370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z24_08375	COG2267	carboxylic ester hydrolase activity
L2Z24_08395	COG3038	cytochrome b561
L2Z24_08400	COG0753	catalase activity
L2Z24_08435	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z24_08445	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z24_08450	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z24_08455	COG0183	Belongs to the thiolase family
L2Z24_08460	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z24_08465	COG1024	Enoyl-CoA hydratase
L2Z24_08470	COG1024	Enoyl-CoA hydratase
L2Z24_08475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z24_08480	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z24_08485	COG3396	Phenylacetate-CoA oxygenase
L2Z24_08490	COG3460	Phenylacetate-CoA oxygenase
L2Z24_08495	COG3396	Phenylacetate-CoA oxygenase
L2Z24_08500	COG2030	dehydratase
L2Z24_08500	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_08505	COG1760	l-serine dehydratase
L2Z24_08510	COG0531	amino acid
L2Z24_08515	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_08530	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z24_08540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z24_08560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z24_08570	COG0789	Transcriptional regulator
L2Z24_08585	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z24_08600	COG2807	transmembrane transport
L2Z24_08605	COG0590	tRNA wobble adenosine to inosine editing
L2Z24_08725	COG1116	anion transmembrane transporter activity
L2Z24_08730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z24_08740	COG0864	Transcriptional regulator
L2Z24_08760	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z24_08765	COG0439	Biotin carboxylase
L2Z24_08780	COG1063	alcohol dehydrogenase
L2Z24_08790	COG1309	transcriptional regulator
L2Z24_08810	COG0038	chloride channel
L2Z24_08815	COG4770	biotin carboxylase activity
L2Z24_08835	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z24_08840	COG0583	DNA-binding transcription factor activity
L2Z24_08890	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z24_08910	COG2814	Major facilitator Superfamily
L2Z24_08925	COG1560	Kdo2-lipid A biosynthetic process
L2Z24_08935	COG5006	permease, DMT superfamily
L2Z24_08940	COG1522	sequence-specific DNA binding
L2Z24_08955	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z24_08965	COG4122	O-methyltransferase activity
L2Z24_08995	COG1538	Outer membrane efflux protein
L2Z24_09000	COG1137	ATPase activity
L2Z24_09005	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z24_09015	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z24_09020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z24_09020	COG0517	IMP dehydrogenase activity
L2Z24_09055	COG2814	Major facilitator Superfamily
L2Z24_09090	COG1278	Cold shock
L2Z24_09095	COG1280	lysine exporter protein (LysE YggA)
L2Z24_09125	COG1570	exodeoxyribonuclease VII activity
L2Z24_09175	COG0583	DNA-binding transcription factor activity
L2Z24_09185	COG4638	Rieske (2fe-2S)
L2Z24_09190	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z24_09195	COG0543	2 iron, 2 sulfur cluster binding
L2Z24_09195	COG0633	Ferredoxin
L2Z24_09200	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_09205	COG3135	benzoate transporter
L2Z24_09210	COG2814	Major facilitator Superfamily
L2Z24_09225	COG1643	Atp-dependent helicase
L2Z24_09230	COG0450	alkyl hydroperoxide reductase
L2Z24_09240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z24_09250	COG3634	alkyl hydroperoxide reductase activity
L2Z24_09270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z24_09275	COG0625	glutathione transferase activity
L2Z24_09285	COG2885	chlorophyll binding
L2Z24_09320	COG0542	response to heat
L2Z24_09335	COG1765	OsmC-like protein
L2Z24_09355	COG0667	Aldo Keto reductase
L2Z24_09370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z24_09380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z24_09390	COG0527	aspartate kinase activity
L2Z24_09400	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z24_09410	COG3038	cytochrome b561
L2Z24_09415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z24_09420	COG2252	PERMEase
L2Z24_09430	COG2072	flavoprotein involved in K transport
L2Z24_09445	COG1741	Belongs to the pirin family
L2Z24_09450	COG1309	transcriptional regulator
L2Z24_09460	COG0300	oxidoreductase activity
L2Z24_09480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2Z24_09555	COG0789	Transcriptional regulator
L2Z24_09620	COG4269	membrane
L2Z24_09635	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z24_09635	COG1902	pentaerythritol trinitrate reductase activity
L2Z24_09645	COG2203	Gaf domain
L2Z24_09645	COG3706	GGDEF domain
L2Z24_09645	COG4251	negative regulation of phosphorylation
L2Z24_09645	COG5001	Diguanylate cyclase
L2Z24_09655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z24_09675	COG4172	Belongs to the ABC transporter superfamily
L2Z24_09680	COG4239	(ABC) transporter, permease
L2Z24_09685	COG4174	ABC transporter (Permease)
L2Z24_09695	COG0741	lytic transglycosylase activity
L2Z24_09695	COG1388	LysM domain
L2Z24_09695	COG0741	lytic transglycosylase activity
L2Z24_09695	COG1388	LysM domain
L2Z24_09700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z24_09740	COG0583	DNA-binding transcription factor activity
L2Z24_09745	COG1279	arginine transmembrane transporter activity
L2Z24_09765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z24_09770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z24_09775	COG0006	proline dipeptidase activity
L2Z24_09815	COG2194	sulfuric ester hydrolase activity
L2Z24_09860	COG0739	heme binding
L2Z24_10185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z24_10215	COG3384	dioxygenase
L2Z24_10225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z24_10230	COG2878	Part of a membrane complex involved in electron transport
L2Z24_10235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z24_10260	COG0768	penicillin binding
L2Z24_10265	COG0742	ribosomal rna small subunit methyltransferase
L2Z24_10280	COG0830	nickel cation binding
L2Z24_10290	COG0804	urea catabolic process
L2Z24_10330	COG1253	flavin adenine dinucleotide binding
L2Z24_10340	COG2851	Citrate transporter
L2Z24_10390	COG1773	rubredoxin
L2Z24_10395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z24_10405	COG0583	DNA-binding transcription factor activity
L2Z24_10430	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z24_10435	COG4181	ATPase activity
L2Z24_10480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z24_10500	COG0306	phosphate transporter
L2Z24_10510	COG3958	Transketolase
L2Z24_10515	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z24_10520	COG2271	Major facilitator Superfamily
L2Z24_10525	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_10530	COG0583	DNA-binding transcription factor activity
L2Z24_10545	COG2223	nitrite transmembrane transporter activity
L2Z24_10550	COG2207	Transcriptional regulator
L2Z24_10555	COG2066	Belongs to the glutaminase family
L2Z24_10560	COG0242	peptide deformylase activity
L2Z24_10565	COG0477	Major facilitator Superfamily
L2Z24_10575	COG0028	Belongs to the TPP enzyme family
L2Z24_10590	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_10595	COG2267	carboxylic ester hydrolase activity
L2Z24_10605	COG2271	Major facilitator Superfamily
L2Z24_10610	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z24_10620	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_10640	COG1414	Transcriptional regulator
L2Z24_10655	COG1024	Enoyl-CoA hydratase
L2Z24_10665	COG1215	transferase activity, transferring glycosyl groups
L2Z24_10670	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z24_10670	COG0726	polysaccharide deacetylase
L2Z24_10680	COG4681	YaeQ
L2Z24_10690	COG0523	cobalamin synthesis protein
L2Z24_10700	COG1607	acyl-coa hydrolase
L2Z24_10710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z24_10715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z24_10720	COG1309	transcriptional regulator
L2Z24_10745	COG2040	homocysteine
L2Z24_10750	COG0531	amino acid
L2Z24_10775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z24_10780	COG0477	Major facilitator Superfamily
L2Z24_10820	COG0405	Gamma-glutamyltransferase
L2Z24_10825	COG2814	Major facilitator Superfamily
L2Z24_10835	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z24_10850	COG1090	epimerase
L2Z24_10870	COG0420	3'-5' exonuclease activity
L2Z24_10895	COG0735	belongs to the Fur family
L2Z24_10900	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z24_10920	COG0121	glutamine amidotransferase
L2Z24_10935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z24_10945	COG0210	DNA helicase
L2Z24_10950	COG2885	chlorophyll binding
L2Z24_10955	COG0204	Acyl-transferase
L2Z24_10970	COG2894	cell division
L2Z24_10990	COG1280	lysine exporter protein (LysE YggA)
L2Z24_10995	COG1674	ftsk spoiiie
L2Z24_10995	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z24_11000	COG0492	ferredoxin-NADP+ reductase activity
L2Z24_11005	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z24_11015	COG0456	acetyltransferase
L2Z24_11060	COG1981	membrane
L2Z24_11075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z24_11075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z24_11095	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_11105	COG0657	acetylesterase activity
L2Z24_11115	COG0473	3-isopropylmalate dehydrogenase activity
L2Z24_11120	COG0583	DNA-binding transcription factor activity
L2Z24_11140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z24_11165	COG0564	pseudouridine synthase activity
L2Z24_11175	COG0358	DNA primase activity
L2Z24_11190	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z24_11220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z24_11250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z24_11260	COG0351	phosphomethylpyrimidine kinase
L2Z24_11260	COG0352	thiamine-phosphate diphosphorylase activity
L2Z24_11260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z24_11265	COG1652	LysM domain
L2Z24_11290	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z24_11295	COG3101	peptidyl-lysine hydroxylation
L2Z24_11300	COG0009	L-threonylcarbamoyladenylate synthase
L2Z24_11305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z24_11310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z24_11325	COG4106	trans-aconitate 2-methyltransferase activity
L2Z24_11340	COG0596	Alpha beta hydrolase
L2Z24_11340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z24_11340	COG2226	methyltransferase
L2Z24_11345	COG1877	trehalose-phosphatase activity
L2Z24_11350	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z24_11355	COG2223	nitrite transmembrane transporter activity
L2Z24_11375	COG1196	nuclear chromosome segregation
L2Z24_11385	COG0730	response to heat
L2Z24_11400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z24_11410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z24_11460	COG0489	protein tyrosine kinase activity
L2Z24_11470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z24_11470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z24_11500	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z24_11505	COG2081	HI0933 family
L2Z24_11515	COG0668	transmembrane transport
L2Z24_11535	COG0583	DNA-binding transcription factor activity
L2Z24_11555	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z24_11560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z24_11590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z24_11630	COG0745	RESPONSE REGULATOR receiver
L2Z24_11650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z24_11660	COG2205	protein histidine kinase activity
L2Z24_11730	COG4993	Dehydrogenase
L2Z24_11750	COG0384	phenazine biosynthesis protein PhzF
L2Z24_11785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z24_11800	COG0583	DNA-binding transcription factor activity
L2Z24_11830	COG0583	DNA-binding transcription factor activity
L2Z24_11845	COG0583	DNA-binding transcription factor activity
L2Z24_11850	COG1053	succinate dehydrogenase
L2Z24_11860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z24_11865	COG2814	Major facilitator Superfamily
L2Z24_11870	COG1960	acyl-CoA dehydrogenase activity
L2Z24_11875	COG0583	DNA-binding transcription factor activity
L2Z24_11880	COG1063	alcohol dehydrogenase
L2Z24_11910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z24_11915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z24_11920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z24_11935	COG3667	copper resistance
L2Z24_11940	COG2132	Multicopper oxidase
L2Z24_11950	COG0561	phosphatase activity
L2Z24_11955	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z24_11980	COG1214	PFAM Peptidase M22, glycoprotease
L2Z24_12030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z24_12040	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z24_12045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z24_12050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z24_12110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z24_12120	COG1846	Transcriptional regulator
L2Z24_12125	COG1764	response to oxidative stress
L2Z24_12165	COG0037	tRNA processing
L2Z24_12175	COG0248	Ppx GppA phosphatase
L2Z24_12205	COG0072	phenylalanine-tRNA ligase activity
L2Z24_12250	COG1238	metal cluster binding
L2Z24_12255	COG0625	glutathione transferase activity
L2Z24_12270	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z24_12275	COG3028	Belongs to the UPF0307 family
L2Z24_12280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z24_12300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z24_12305	COG0617	tRNA 3'-terminal CCA addition
L2Z24_12310	COG1555	photosystem II stabilization
L2Z24_12315	COG3956	TIGRFAM MazG family protein
L2Z24_12325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z24_12345	COG0784	Response regulator, receiver
L2Z24_12345	COG2205	protein histidine kinase activity
L2Z24_12345	COG5002	protein histidine kinase activity
L2Z24_12350	COG1024	Enoyl-CoA hydratase
L2Z24_12370	COG3622	Belongs to the hyi family
L2Z24_12400	COG0697	spore germination
L2Z24_12410	COG2814	Major facilitator Superfamily
L2Z24_12415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z24_12425	COG0583	DNA-binding transcription factor activity
L2Z24_12435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z24_12450	COG0084	hydrolase, TatD family'
L2Z24_12465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z24_12495	COG0440	acetolactate synthase activity
L2Z24_12500	COG0028	Belongs to the TPP enzyme family
L2Z24_12525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z24_12530	COG0577	efflux transmembrane transporter activity
L2Z24_12530	COG1136	(ABC) transporter
L2Z24_12535	COG1538	Outer membrane efflux protein
L2Z24_12550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z24_12555	COG1162	GTPase activity
L2Z24_12565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z24_12585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z24_12590	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_12630	COG2986	histidine ammonia-lyase
L2Z24_12645	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z24_12655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z24_12700	COG1426	Protein conserved in bacteria
L2Z24_12735	COG0793	Belongs to the peptidase S41A family
L2Z24_12750	COG2267	carboxylic ester hydrolase activity
L2Z24_12760	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_12765	COG3265	gluconokinase activity
L2Z24_12775	COG0800	Aldolase
L2Z24_12785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z24_12790	COG0280	phosphate acetyltransferase
L2Z24_12790	COG0857	belongs to the CobB CobQ family
L2Z24_12795	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z24_12795	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z24_12815	COG0740	serine-type endopeptidase activity
L2Z24_12825	COG4774	siderophore transport
L2Z24_12835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z24_12845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z24_12845	COG2813	Specifically methylates the guanine in position
L2Z24_12945	COG0788	formyltetrahydrofolate deformylase activity
L2Z24_12970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z24_12970	COG4651	solute:proton antiporter activity
L2Z24_12990	COG0724	RNA recognition motif
L2Z24_12995	COG0210	DNA helicase
L2Z24_13020	COG1733	regulation of RNA biosynthetic process
L2Z24_13030	COG2900	Belongs to the SlyX family
L2Z24_13035	COG0488	(ABC) transporter
L2Z24_13040	COG1280	lysine exporter protein (LysE YggA)
L2Z24_13045	COG1560	Kdo2-lipid A biosynthetic process
L2Z24_13055	COG1301	dicarboxylic acid transport
L2Z24_13110	COG0473	3-isopropylmalate dehydrogenase activity
L2Z24_13175	COG3293	Transposase
L2Z24_13180	COG0583	DNA-binding transcription factor activity
L2Z24_13190	COG0625	glutathione transferase activity
L2Z24_13195	COG2378	regulation of single-species biofilm formation
L2Z24_13200	COG0546	phosphoglycolate phosphatase activity
L2Z24_13210	COG1530	ribonuclease E activity
L2Z24_13215	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z24_13230	COG0583	DNA-binding transcription factor activity
L2Z24_13235	COG4221	oxidoreductase activity
L2Z24_13240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z24_13250	COG0534	Mate efflux family protein
L2Z24_13265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z24_13305	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z24_13310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z24_13325	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z24_13335	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z24_13335	COG0644	oxidoreductase
L2Z24_13340	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z24_13345	COG4535	Mg2 and Co2 transporter CorC
L2Z24_13355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z24_13375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z24_13380	COG0475	glutathione-regulated potassium exporter activity
L2Z24_13380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z24_13385	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z24_13395	COG0484	heat shock protein binding
L2Z24_13400	COG0789	Transcriptional regulator
L2Z24_13405	COG0598	Magnesium transport protein CorA
L2Z24_13420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z24_13425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z24_13430	COG1074	ATP-dependent DNA helicase activity
L2Z24_13435	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z24_13455	COG2226	methyltransferase
L2Z24_13470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z24_13475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z24_13490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z24_13490	COG2111	Na H antiporter
L2Z24_13495	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z24_13500	COG0651	ATP synthesis coupled electron transport
L2Z24_13505	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z24_13510	COG2212	antiporter activity
L2Z24_13515	COG1320	monovalent cation:proton antiporter activity
L2Z24_13530	COG0195	Participates in both transcription termination and antitermination
L2Z24_13585	COG0237	dephospho-CoA kinase activity
L2Z24_13595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z24_13610	COG0497	DNA recombination
L2Z24_13620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z24_13650	COG2169	Transcriptional regulator
L2Z24_13650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z24_13655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z24_13720	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z24_13735	COG0326	Molecular chaperone. Has ATPase activity
L2Z24_13750	COG2056	Na+-H+ antiporter family
L2Z24_13755	COG0596	Alpha beta hydrolase
L2Z24_13860	COG0546	phosphoglycolate phosphatase activity
L2Z24_13865	COG1716	ATPase activity
L2Z24_13910	COG0181	hydroxymethylbilane synthase activity
L2Z24_13920	COG3275	phosphorelay sensor kinase activity
L2Z24_13940	COG1538	Outer membrane efflux protein
L2Z24_13945	COG0697	spore germination
L2Z24_13970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z24_13975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z24_13980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z24_13985	COG0772	Belongs to the SEDS family
L2Z24_14010	COG4974	Belongs to the 'phage' integrase family
L2Z24_14015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z24_14025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z24_14035	COG2197	response regulator
L2Z24_14050	COG0793	Belongs to the peptidase S41A family
L2Z24_14055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z24_14060	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z24_14100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z24_14100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z24_14110	COG0004	ammonium transporteR
L2Z24_14115	COG0347	Belongs to the P(II) protein family
L2Z24_14175	COG0659	secondary active sulfate transmembrane transporter activity
L2Z24_14180	COG0589	response to stress
L2Z24_14220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z24_14255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z24_14265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z24_14285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z24_14300	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z24_14310	COG0477	Major facilitator Superfamily
L2Z24_14315	COG2860	membrane
L2Z24_14325	COG1253	flavin adenine dinucleotide binding
L2Z24_14335	COG0477	Major facilitator Superfamily
L2Z24_14345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z24_14385	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z24_14395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z24_14465	COG0758	DNA mediated transformation
L2Z24_14475	COG0697	spore germination
L2Z24_14480	COG1309	transcriptional regulator
L2Z24_14495	COG0386	Belongs to the glutathione peroxidase family
L2Z24_14560	COG1121	(ABC) transporter
L2Z24_14565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z24_14570	COG1280	lysine exporter protein (LysE YggA)
L2Z24_14575	COG2837	iron assimilation
L2Z24_14580	COG0281	malic enzyme
L2Z24_14625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z24_14625	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z24_14630	COG4399	Belongs to the UPF0754 family
L2Z24_14635	COG2259	Doxx family
L2Z24_14640	COG0586	Pfam SNARE associated Golgi protein
L2Z24_14655	COG1192	Involved in chromosome partitioning
L2Z24_14665	COG0271	Belongs to the BolA IbaG family
L2Z24_14685	COG2267	carboxylic ester hydrolase activity
L2Z24_14705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z24_14705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z24_14705	COG3321	synthase
L2Z24_14705	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z24_14710	COG1960	acyl-CoA dehydrogenase activity
L2Z24_14720	COG2197	response regulator
L2Z24_14730	COG3916	Acyl-homoserine-lactone synthase
L2Z24_14735	COG0477	Major facilitator Superfamily
L2Z24_14740	COG1024	Enoyl-CoA hydratase
L2Z24_14745	COG1024	Enoyl-CoA hydratase
L2Z24_14750	COG1960	acyl-CoA dehydrogenase activity
L2Z24_14755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z24_14775	COG1113	amino acid transport
L2Z24_14780	COG1113	amino acid transport
L2Z24_14785	COG0251	oxidation-reduction process
L2Z24_14825	COG0564	pseudouridine synthase activity
L2Z24_14875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z24_14890	COG1802	Transcriptional regulator
L2Z24_14895	COG1448	Aminotransferase
L2Z24_14900	COG0277	FAD linked oxidase domain protein
L2Z24_14910	COG2186	Transcriptional regulator
L2Z24_14920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z24_14925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z24_14940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z24_14950	COG0110	maltose O-acetyltransferase activity
L2Z24_14955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z24_14985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z24_14990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z24_14995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z24_15035	COG0728	peptidoglycan biosynthetic process
L2Z24_15040	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z24_15095	COG0546	phosphoglycolate phosphatase activity
L2Z24_15100	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z24_15120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z24_15125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z24_15130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z24_15135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z24_15140	COG1116	anion transmembrane transporter activity
L2Z24_15145	COG1309	transcriptional regulator
L2Z24_15150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z24_15160	COG0196	riboflavin kinase activity
L2Z24_15165	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z24_15175	COG1047	Peptidyl-prolyl cis-trans
L2Z24_15215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z24_15220	COG0657	acetylesterase activity
L2Z24_15240	COG0583	DNA-binding transcription factor activity
L2Z24_15270	COG2951	lytic endotransglycosylase activity
L2Z24_15275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z24_15290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z24_15300	COG0671	phosphoesterase, PA-phosphatase related
L2Z24_15305	COG0861	Integral membrane protein TerC family
L2Z24_15315	COG0754	glutathionylspermidine amidase activity
L2Z24_15325	COG0402	S-adenosylhomocysteine deaminase activity
L2Z24_15340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z24_15345	COG1230	cation diffusion facilitator family transporter
L2Z24_15360	COG0706	membrane insertase activity
L2Z24_15385	COG0592	DNA-directed DNA polymerase activity
L2Z24_15395	COG0187	DNA topoisomerase II activity
L2Z24_15405	COG0586	Pfam SNARE associated Golgi protein
L2Z24_15410	COG0488	(ABC) transporter
L2Z24_15435	COG0596	Alpha beta hydrolase
L2Z24_15440	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z24_15445	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z24_15485	COG0733	neurotransmitter:sodium symporter activity
L2Z24_15525	COG2233	PERMEase
L2Z24_15540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z24_15575	COG2814	Major facilitator Superfamily
L2Z24_15580	COG0656	L-ascorbic acid biosynthetic process
L2Z24_15585	COG0583	DNA-binding transcription factor activity
L2Z24_15600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z24_15605	COG1064	alcohol dehydrogenase
L2Z24_15610	COG2818	Glycosylase
L2Z24_15625	COG1194	a g-specific adenine glycosylase
L2Z24_15645	COG2983	Belongs to the UPF0260 family
L2Z24_15650	COG2133	pyrroloquinoline quinone binding
L2Z24_15655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z24_15660	COG2116	formate transmembrane transporter activity
L2Z24_15680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z24_15685	COG1335	isochorismatase
L2Z24_15690	COG0385	Bile acid
L2Z24_15695	COG0534	Mate efflux family protein
L2Z24_15700	COG1683	Conserved Protein
L2Z24_15720	COG0625	glutathione transferase activity
L2Z24_15730	COG1113	amino acid transport
L2Z24_15740	COG0523	cobalamin synthesis protein
L2Z24_15750	COG2188	Transcriptional regulator
L2Z24_15780	COG0010	Belongs to the arginase family
L2Z24_15795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z24_15800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z24_15810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z24_15815	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z24_15915	COG0534	Mate efflux family protein
L2Z24_15920	COG0436	Aminotransferase
L2Z24_15925	COG2733	membrane
L2Z24_15940	COG2918	glutathione biosynthetic process
L2Z24_15955	COG0791	NLP P60 protein
L2Z24_15955	COG1388	LysM domain
L2Z24_15970	COG3150	esterase
L2Z24_15980	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z24_15990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z24_16000	COG2233	PERMEase
L2Z24_16005	COG2351	hydroxyisourate hydrolase activity
L2Z24_16040	COG3706	GGDEF domain
L2Z24_16055	COG1393	Belongs to the ArsC family
L2Z24_16060	COG0708	Exodeoxyribonuclease III
L2Z24_16080	COG0189	ligase activity
L2Z24_16100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z24_16110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z24_16125	COG4942	peptidase
L2Z24_16135	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z24_16145	COG2119	membrane
L2Z24_16150	COG4774	siderophore transport
L2Z24_16155	COG0426	domain, Protein
L2Z24_16155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z24_16180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z24_16205	COG1902	pentaerythritol trinitrate reductase activity
L2Z24_16210	COG1519	Transferase
L2Z24_16215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z24_16220	COG0668	transmembrane transport
L2Z24_16230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z24_16235	COG1335	isochorismatase
L2Z24_16240	COG1522	sequence-specific DNA binding
L2Z24_16245	COG3328	transposase activity
L2Z24_16270	COG0784	Response regulator, receiver
L2Z24_16270	COG2198	Histidine kinase
L2Z24_16270	COG2205	protein histidine kinase activity
L2Z24_16275	COG3162	membrane
L2Z24_16280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z24_16290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z24_16310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z24_16315	COG1309	transcriptional regulator
L2Z24_16335	COG0352	thiamine-phosphate diphosphorylase activity
L2Z24_16335	COG0351	phosphomethylpyrimidine kinase
L2Z24_16335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z24_16345	COG2814	Major facilitator Superfamily
L2Z24_16360	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z24_16370	COG1113	amino acid transport
L2Z24_16380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z24_16385	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_16395	COG1335	isochorismatase
L2Z24_16425	COG2814	Major facilitator Superfamily
L2Z24_16430	COG0583	DNA-binding transcription factor activity
L2Z24_16450	COG0667	Aldo Keto reductase
L2Z24_16485	COG1733	regulation of RNA biosynthetic process
L2Z24_16490	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z24_16555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z24_16570	COG2329	Antibiotic biosynthesis monooxygenase
L2Z24_16600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z24_16630	COG0427	acetyl-CoA hydrolase
L2Z24_16655	COG0659	secondary active sulfate transmembrane transporter activity
L2Z24_16660	COG4221	oxidoreductase activity
L2Z24_16665	COG2873	o-acetylhomoserine
L2Z24_16670	COG0488	(ABC) transporter
L2Z24_16755	COG0833	amino acid
L2Z24_16800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z24_16805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z24_16820	COG2226	methyltransferase
L2Z24_16870	COG0067	glutamate synthase
L2Z24_16870	COG0069	glutamate synthase activity
L2Z24_16870	COG0070	glutamate synthase
L2Z24_16875	COG0493	'glutamate synthase
L2Z24_16885	COG1704	LemA family
L2Z24_16890	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z24_16910	COG3307	-O-antigen
L2Z24_16930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z24_16945	COG0194	GDP metabolic process
L2Z24_16995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z24_17015	COG5380	lipid catabolic process
L2Z24_17020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z24_17045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z24_17050	COG0277	FAD linked oxidase domain protein
L2Z24_17060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z24_17065	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z24_17080	COG1289	transmembrane transporter activity
L2Z24_17090	COG0628	permease
L2Z24_17095	COG1192	Involved in chromosome partitioning
L2Z24_17125	COG3293	Transposase
L2Z24_17130	COG0833	amino acid
L2Z24_17135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z24_17140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z24_17150	COG1012	belongs to the aldehyde dehydrogenase family
L2Z24_17190	COG0583	DNA-binding transcription factor activity
L2Z24_17235	COG0517	IMP dehydrogenase activity
L2Z24_17240	COG1983	PspC domain protein
L2Z24_17250	COG1960	acyl-CoA dehydrogenase activity
L2Z24_17265	COG0408	coproporphyrinogen oxidase activity
L2Z24_17285	COG0513	Belongs to the DEAD box helicase family
L2Z24_17295	COG1127	ABC transporter
L2Z24_17300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z24_17310	COG2854	intermembrane phospholipid transfer
L2Z24_17320	COG0598	Magnesium transport protein CorA
L2Z24_17330	COG0494	nUDIX hydrolase
L2Z24_17335	COG1040	competence protein
L2Z24_17340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z24_17360	COG1946	Acyl-CoA thioesterase
L2Z24_17365	COG1301	dicarboxylic acid transport
L2Z24_17380	COG1959	2 iron, 2 sulfur cluster binding
L2Z24_17385	COG1017	nitric oxide dioxygenase activity
L2Z24_17385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z24_17390	COG0433	COG0433 Predicted ATPase
L2Z24_17395	COG0626	cystathionine gamma-synthase activity
L2Z24_17550	COG1960	acyl-CoA dehydrogenase activity
L2Z24_17555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z24_17585	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z24_17590	COG0339	signal peptide processing
L2Z24_17595	COG0557	exoribonuclease II activity
L2Z24_17640	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z24_17645	COG2169	Transcriptional regulator
L2Z24_17650	COG0697	spore germination
L2Z24_17655	COG1295	ribonuclease BN
L2Z24_17690	COG1702	phosphate starvation-inducible protein PhoH
L2Z24_17700	COG1196	nuclear chromosome segregation
L2Z24_17700	COG0741	lytic transglycosylase activity
L2Z24_17700	COG0739	heme binding
L2Z24_17735	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z24_17740	COG1183	phosphatidylcholine synthase activity
L2Z24_17785	COG1960	acyl-CoA dehydrogenase activity
L2Z24_17790	COG1309	transcriptional regulator
L2Z24_17805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z24_17810	COG1960	acyl-CoA dehydrogenase activity
L2Z24_17830	COG2969	positive regulation of protein catabolic process
L2Z24_17840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z24_17855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z24_17860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z24_18025	COG5410	chromosome segregation
L2Z24_18130	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z24_18290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z24_18300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z24_18305	COG1408	metallophosphoesterase
L2Z24_18315	COG2199	diguanylate cyclase activity
L2Z24_18385	COG3293	Transposase
