locus-tag	class	description
L2Z45_00040	COG1960	acyl-CoA dehydrogenase activity
L2Z45_00045	COG1309	transcriptional regulator
L2Z45_00060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z45_00065	COG1960	acyl-CoA dehydrogenase activity
L2Z45_00085	COG2969	positive regulation of protein catabolic process
L2Z45_00095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z45_00110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z45_00115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z45_00135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z45_00145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z45_00150	COG1408	metallophosphoesterase
L2Z45_00160	COG2199	diguanylate cyclase activity
L2Z45_00220	COG1607	acyl-coa hydrolase
L2Z45_00250	COG2350	Protein conserved in bacteria
L2Z45_00260	COG0613	PHP domain protein
L2Z45_00265	COG3781	membrane
L2Z45_00275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z45_00290	COG1862	Preprotein translocase
L2Z45_00320	COG2205	protein histidine kinase activity
L2Z45_00325	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z45_00345	COG0726	polysaccharide deacetylase
L2Z45_00350	COG0463	Glycosyl transferase, family 2
L2Z45_00355	COG0438	transferase activity, transferring glycosyl groups
L2Z45_00370	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z45_00420	COG1960	acyl-CoA dehydrogenase activity
L2Z45_00425	COG1960	acyl-CoA dehydrogenase activity
L2Z45_00435	COG2205	protein histidine kinase activity
L2Z45_00440	COG0745	RESPONSE REGULATOR receiver
L2Z45_00445	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z45_00465	COG2096	Adenosyltransferase
L2Z45_00515	COG0285	dihydrofolate synthase activity
L2Z45_00535	COG0450	alkyl hydroperoxide reductase
L2Z45_00550	COG0477	Major facilitator Superfamily
L2Z45_00555	COG1272	protein, Hemolysin III
L2Z45_00565	COG2153	protein acetylation
L2Z45_00585	COG0183	Belongs to the thiolase family
L2Z45_00590	COG2207	Transcriptional regulator
L2Z45_00610	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z45_00630	COG0183	Belongs to the thiolase family
L2Z45_00640	COG2885	chlorophyll binding
L2Z45_00640	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z45_00650	COG1690	Belongs to the RtcB family
L2Z45_00655	COG0833	amino acid
L2Z45_00665	COG2233	PERMEase
L2Z45_00670	COG1217	gtp-binding protein TYPA
L2Z45_00695	COG2094	Belongs to the DNA glycosylase MPG family
L2Z45_00700	COG4772	TonB-dependent receptor
L2Z45_00705	COG1902	pentaerythritol trinitrate reductase activity
L2Z45_00720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z45_00725	COG0354	folic acid binding
L2Z45_00735	COG3189	MarR family transcriptional regulator
L2Z45_00740	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z45_00745	COG3422	double-strand break repair
L2Z45_00785	COG0840	transmembrane signaling receptor activity
L2Z45_00815	COG5510	response to toxic substance
L2Z45_00825	COG2832	Protein of unknown function (DUF454)
L2Z45_00830	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z45_00870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z45_00880	COG1289	transmembrane transporter activity
L2Z45_00885	COG2814	Major facilitator Superfamily
L2Z45_00905	COG1115	amino acid carrier protein
L2Z45_00910	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z45_00915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z45_00920	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z45_00945	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z45_00955	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z45_00960	COG1077	Cell shape determining protein MreB Mrl
L2Z45_00965	COG1792	Involved in formation and maintenance of cell shape
L2Z45_00970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z45_00975	COG0424	maF-like protein
L2Z45_00980	COG1530	ribonuclease E activity
L2Z45_00990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z45_01000	COG0560	Phosphoserine phosphatase
L2Z45_01010	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z45_01035	COG2207	Transcriptional regulator
L2Z45_01055	COG1113	amino acid transport
L2Z45_01060	COG2828	Protein conserved in bacteria
L2Z45_01065	COG0142	geranyltranstransferase activity
L2Z45_01070	COG2315	Protein conserved in bacteria
L2Z45_01085	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z45_01120	COG4372	Transposase
L2Z45_01130	COG0745	RESPONSE REGULATOR receiver
L2Z45_01135	COG0642	Histidine kinase
L2Z45_01145	COG0004	ammonium transporteR
L2Z45_01150	COG0583	DNA-binding transcription factor activity
L2Z45_01170	COG0525	valine-tRNA ligase activity
L2Z45_01180	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_01190	COG0393	Putative heavy-metal-binding
L2Z45_01195	COG0393	Putative heavy-metal-binding
L2Z45_01200	COG1538	Outer membrane efflux protein
L2Z45_01210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z45_01220	COG0671	phosphoesterase, PA-phosphatase related
L2Z45_01250	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z45_01265	COG1648	precorrin-2 dehydrogenase activity
L2Z45_01265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z45_01270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z45_01275	COG1733	regulation of RNA biosynthetic process
L2Z45_01285	COG0531	amino acid
L2Z45_01300	COG0321	lipoyl(octanoyl) transferase activity
L2Z45_01305	COG2921	Belongs to the UPF0250 family
L2Z45_01345	COG2009	succinate dehydrogenase
L2Z45_01350	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z45_01355	COG1053	succinate dehydrogenase
L2Z45_01360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z45_01385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z45_01405	COG2354	Protein conserved in bacteria
L2Z45_01410	COG2321	neutral zinc metallopeptidase
L2Z45_01430	COG2843	Capsule synthesis protein
L2Z45_01445	COG0589	response to stress
L2Z45_01465	COG0505	Belongs to the CarA family
L2Z45_01490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z45_01495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z45_01545	COG0477	Major facilitator Superfamily
L2Z45_01550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z45_01565	COG1597	lipid kinase activity
L2Z45_01570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z45_01595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z45_01600	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z45_01620	COG0741	lytic transglycosylase activity
L2Z45_01640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z45_01655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z45_01685	COG0778	Nitroreductase
L2Z45_01700	COG1929	Belongs to the glycerate kinase type-1 family
L2Z45_01705	COG0243	molybdopterin cofactor binding
L2Z45_01710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z45_01715	COG3339	Conserved Protein
L2Z45_01725	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z45_01740	COG1113	amino acid transport
L2Z45_01750	COG0019	diaminopimelate decarboxylase activity
L2Z45_01760	COG2267	carboxylic ester hydrolase activity
L2Z45_01765	COG1280	lysine exporter protein (LysE YggA)
L2Z45_01770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z45_01820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z45_01850	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z45_01855	COG1136	(ABC) transporter
L2Z45_01860	COG0658	competence protein
L2Z45_01860	COG2333	competence protein COMEC
L2Z45_01870	COG0616	signal peptide processing
L2Z45_01870	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z45_01875	COG0596	Alpha beta hydrolase
L2Z45_01880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z45_01890	COG0628	permease
L2Z45_01925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z45_01945	COG0823	Involved in the tonB-independent uptake of proteins
L2Z45_01965	COG0824	Thioesterase
L2Z45_01970	COG1473	amidohydrolase
L2Z45_01990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z45_01990	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z45_01995	COG2814	Major facilitator Superfamily
L2Z45_02005	COG1024	Enoyl-CoA hydratase
L2Z45_02010	COG1051	belongs to the nudix hydrolase family
L2Z45_02010	COG1056	cytidyltransferase-related domain
L2Z45_02020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z45_02035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z45_02050	COG4625	pathogenesis
L2Z45_02055	COG0583	DNA-binding transcription factor activity
L2Z45_02060	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z45_02065	COG4208	sulfate ABC transporter
L2Z45_02070	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z45_02080	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z45_02085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z45_02090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z45_02110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z45_02125	COG0681	Belongs to the peptidase S26 family
L2Z45_02140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z45_02150	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z45_02155	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z45_02165	COG4221	oxidoreductase activity
L2Z45_02195	COG0436	Aminotransferase
L2Z45_02215	COG0556	nucleotide-excision repair
L2Z45_02270	COG2070	2-Nitropropane dioxygenase
L2Z45_02300	COG1215	transferase activity, transferring glycosyl groups
L2Z45_02315	COG0415	Belongs to the DNA photolyase family
L2Z45_02325	COG1252	NADH dehydrogenase
L2Z45_02330	COG1686	Belongs to the peptidase S11 family
L2Z45_02345	COG1187	pseudouridine synthase activity
L2Z45_02365	COG0477	Major facilitator Superfamily
L2Z45_02370	COG0583	DNA-binding transcription factor activity
L2Z45_02375	COG1823	symporter activity
L2Z45_02385	COG0612	Peptidase, M16
L2Z45_02410	COG0352	thiamine-phosphate diphosphorylase activity
L2Z45_02445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z45_02460	COG1309	transcriptional regulator
L2Z45_02470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z45_02475	COG0076	glutamate decarboxylase activity
L2Z45_02485	COG1522	sequence-specific DNA binding
L2Z45_02490	COG3961	Belongs to the TPP enzyme family
L2Z45_02495	COG1113	amino acid transport
L2Z45_02500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z45_02505	COG0573	inorganic phosphate transmembrane transporter activity
L2Z45_02515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z45_02520	COG0616	signal peptide processing
L2Z45_02555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z45_02560	COG1686	Belongs to the peptidase S11 family
L2Z45_02585	COG0583	DNA-binding transcription factor activity
L2Z45_02590	COG1067	ATP-dependent peptidase activity
L2Z45_02635	COG1966	Carbon starvation protein
L2Z45_02640	COG2879	small protein
L2Z45_02675	COG2508	Transcriptional regulator
L2Z45_02675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z45_02725	COG1113	amino acid transport
L2Z45_02730	COG0583	DNA-binding transcription factor activity
L2Z45_02735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z45_02740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z45_02750	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_02760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z45_02765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z45_02765	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z45_02800	COG2814	Major facilitator Superfamily
L2Z45_02805	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z45_02815	COG1309	transcriptional regulator
L2Z45_02835	COG1741	Belongs to the pirin family
L2Z45_02845	COG2964	Protein conserved in bacteria
L2Z45_02860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z45_02865	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z45_02870	COG4605	iron ion homeostasis
L2Z45_02875	COG4604	ABC transporter, ATP-binding protein
L2Z45_02880	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z45_02885	COG4774	siderophore transport
L2Z45_02895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z45_02900	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z45_02905	COG1535	isochorismatase
L2Z45_02905	COG3433	isochorismatase activity
L2Z45_02920	COG1132	(ABC) transporter
L2Z45_02925	COG1132	(ABC) transporter
L2Z45_02930	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z45_02940	COG1169	isochorismate synthase
L2Z45_02955	COG3739	integral membrane protein
L2Z45_02980	COG0302	gtp cyclohydrolase
L2Z45_02990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z45_03025	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z45_03040	COG0174	glutamine synthetase
L2Z45_03050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z45_03085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z45_03090	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z45_03100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z45_03120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z45_03125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z45_03130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z45_03145	COG1960	acyl-CoA dehydrogenase activity
L2Z45_03150	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z45_03155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z45_03165	COG2223	nitrite transmembrane transporter activity
L2Z45_03175	COG0024	Methionine aminopeptidase
L2Z45_03180	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z45_03195	COG2207	Transcriptional regulator
L2Z45_03220	COG2951	lytic endotransglycosylase activity
L2Z45_03225	COG0772	Belongs to the SEDS family
L2Z45_03240	COG0842	Transport permease protein
L2Z45_03245	COG1131	(ABC) transporter
L2Z45_03290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z45_03305	COG4215	(ABC) transporter
L2Z45_03310	COG4160	amino acid transport
L2Z45_03315	COG4598	ABC transporter
L2Z45_03325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z45_03330	COG0826	peptidase U32
L2Z45_03335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z45_03350	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z45_03360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z45_03375	COG0642	Histidine kinase
L2Z45_03385	COG0494	nUDIX hydrolase
L2Z45_03395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z45_03400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z45_03405	COG3139	Protein of unknown function (DUF1315)
L2Z45_03410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z45_03415	COG1301	dicarboxylic acid transport
L2Z45_03420	COG1960	acyl-CoA dehydrogenase activity
L2Z45_03425	COG2819	hydrolase of the alpha beta superfamily
L2Z45_03435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z45_03445	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z45_03450	COG1234	tRNA 3'-trailer cleavage
L2Z45_03480	COG2363	Small membrane protein
L2Z45_03505	COG0513	Belongs to the DEAD box helicase family
L2Z45_03515	COG0778	Nitroreductase
L2Z45_03545	COG1286	toxin biosynthetic process
L2Z45_03570	COG4783	chaperone-mediated protein folding
L2Z45_03575	COG1610	YqeY-like protein
L2Z45_03675	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z45_03700	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z45_03705	COG0786	glutamate:sodium symporter activity
L2Z45_03715	COG2186	Transcriptional regulator
L2Z45_03765	COG0477	Major facilitator Superfamily
L2Z45_03795	COG2985	domain, Protein
L2Z45_03805	COG2995	paraquat-inducible protein a
L2Z45_03810	COG3008	intermembrane lipid transfer
L2Z45_03810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z45_03820	COG1794	racemase activity, acting on amino acids and derivatives
L2Z45_03850	COG1301	dicarboxylic acid transport
L2Z45_03860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z45_03865	COG2011	ABC-type metal ion transport system permease component
L2Z45_03870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z45_03875	COG1464	Belongs to the NlpA lipoprotein family
L2Z45_03880	COG0151	Belongs to the GarS family
L2Z45_03885	COG0138	bifunctional purine biosynthesis protein purh
L2Z45_03890	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z45_03920	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z45_03930	COG1305	Transglutaminase-like
L2Z45_03940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z45_03945	COG0305	Participates in initiation and elongation during chromosome replication
L2Z45_03975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z45_03985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z45_03990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z45_04015	COG0726	polysaccharide deacetylase
L2Z45_04015	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z45_04020	COG1215	transferase activity, transferring glycosyl groups
L2Z45_04025	COG3658	cytochrome
L2Z45_04035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z45_04050	COG0583	DNA-binding transcription factor activity
L2Z45_04070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z45_04075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z45_04090	COG1960	acyl-CoA dehydrogenase activity
L2Z45_04095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z45_04100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z45_04125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z45_04130	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z45_04140	COG2205	protein histidine kinase activity
L2Z45_04145	COG0745	RESPONSE REGULATOR receiver
L2Z45_04150	COG0174	glutamine synthetase
L2Z45_04170	COG0729	surface antigen
L2Z45_04195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z45_04200	COG2814	Major facilitator Superfamily
L2Z45_04215	COG0583	DNA-binding transcription factor activity
L2Z45_04230	COG1187	pseudouridine synthase activity
L2Z45_04250	COG0802	atpase or kinase
L2Z45_04255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z45_04265	COG1923	regulation of RNA biosynthetic process
L2Z45_04270	COG0697	spore germination
L2Z45_04285	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z45_04295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z45_04300	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z45_04300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z45_04305	COG4302	ethanolamine ammonia-lyase activity
L2Z45_04310	COG4303	Ethanolamine ammonia lyase large subunit
L2Z45_04315	COG0531	amino acid
L2Z45_04335	COG1454	alcohol dehydrogenase
L2Z45_04340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z45_04350	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z45_04370	COG0308	aminopeptidase N
L2Z45_04380	COG4221	oxidoreductase activity
L2Z45_04390	COG1605	Chorismate mutase
L2Z45_04410	COG1309	transcriptional regulator
L2Z45_04420	COG0668	transmembrane transport
L2Z45_04450	COG4773	Receptor
L2Z45_04470	COG0488	(ABC) transporter
L2Z45_04475	COG0589	response to stress
L2Z45_04500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z45_04510	COG3135	benzoate transporter
L2Z45_04515	COG1522	sequence-specific DNA binding
L2Z45_04525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z45_04530	COG0583	DNA-binding transcription factor activity
L2Z45_04540	COG0183	Belongs to the thiolase family
L2Z45_04550	COG2030	dehydratase
L2Z45_04555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z45_04570	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z45_04580	COG0824	Thioesterase
L2Z45_04585	COG1454	alcohol dehydrogenase
L2Z45_04595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z45_04615	COG0069	glutamate synthase activity
L2Z45_04635	COG2814	Major facilitator Superfamily
L2Z45_04650	COG0511	ligase activity, forming carbon-carbon bonds
L2Z45_04670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z45_04670	COG1116	anion transmembrane transporter activity
L2Z45_04675	COG0745	RESPONSE REGULATOR receiver
L2Z45_04685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z45_04685	COG2146	nitrite reductase [NAD(P)H] activity
L2Z45_04690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z45_04695	COG0243	molybdopterin cofactor binding
L2Z45_04705	COG0243	molybdopterin cofactor binding
L2Z45_04710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z45_04725	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z45_04725	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z45_04730	COG0303	'Molybdopterin
L2Z45_04740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z45_04745	COG0697	spore germination
L2Z45_04765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z45_04770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z45_04825	COG2204	response regulator
L2Z45_04830	COG3852	Histidine kinase
L2Z45_04850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z45_04855	COG0575	Belongs to the CDS family
L2Z45_04890	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z45_04905	COG2137	regulation of response to DNA damage stimulus
L2Z45_04915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z45_04920	COG1011	Hydrolase
L2Z45_04945	COG1522	sequence-specific DNA binding
L2Z45_04955	COG1113	amino acid transport
L2Z45_04975	COG0659	secondary active sulfate transmembrane transporter activity
L2Z45_04980	COG2135	peptidase activity
L2Z45_04990	COG4372	Transposase
L2Z45_05010	COG3300	MHYT domain
L2Z45_05010	COG5001	Diguanylate cyclase
L2Z45_05030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z45_05030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z45_05030	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z45_05035	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z45_05040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z45_05040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z45_05070	COG0024	Methionine aminopeptidase
L2Z45_05075	COG0583	DNA-binding transcription factor activity
L2Z45_05085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z45_05090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z45_05095	COG0517	IMP dehydrogenase activity
L2Z45_05095	COG0516	GMP reductase activity
L2Z45_05120	COG0552	protein localization to endoplasmic reticulum
L2Z45_05130	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z45_05145	COG4890	Cyd operon protein YbgT
L2Z45_05150	COG1294	oxidase, subunit
L2Z45_05170	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z45_05180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z45_05185	COG4774	siderophore transport
L2Z45_05200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z45_05205	COG0569	domain protein
L2Z45_05210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z45_05240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z45_05245	COG0542	response to heat
L2Z45_05270	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z45_05270	COG1902	pentaerythritol trinitrate reductase activity
L2Z45_05315	COG2323	membrane
L2Z45_05320	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z45_05330	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z45_05335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z45_05340	COG0183	Belongs to the thiolase family
L2Z45_05345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z45_05350	COG0596	Alpha beta hydrolase
L2Z45_05355	COG2271	Major facilitator Superfamily
L2Z45_05360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z45_05365	COG3485	protocatechuate 3,4-dioxygenase
L2Z45_05370	COG3485	protocatechuate 3,4-dioxygenase
L2Z45_05375	COG0710	3-dehydroquinate dehydratase activity
L2Z45_05380	COG3420	alginic acid biosynthetic process
L2Z45_05385	COG3659	wide pore channel activity
L2Z45_05390	COG4993	Dehydrogenase
L2Z45_05400	COG2391	methyltransferase activity
L2Z45_05420	COG1414	Transcriptional regulator
L2Z45_05425	COG0583	DNA-binding transcription factor activity
L2Z45_05430	COG1960	acyl-CoA dehydrogenase activity
L2Z45_05455	COG2814	Major facilitator Superfamily
L2Z45_05465	COG0154	amidase activity
L2Z45_05485	COG4638	Rieske (2fe-2S)
L2Z45_05495	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_05505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z45_05515	COG3733	amine oxidase
L2Z45_05525	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_05535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z45_05540	COG0183	Belongs to the thiolase family
L2Z45_05545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z45_05550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z45_05560	COG4829	muconolactone delta-isomerase
L2Z45_05565	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z45_05570	COG0583	DNA-binding transcription factor activity
L2Z45_05580	COG2186	Transcriptional regulator
L2Z45_05600	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_05620	COG1960	acyl-CoA dehydrogenase activity
L2Z45_05625	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_05640	COG3162	membrane
L2Z45_05655	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_05670	COG0753	catalase activity
L2Z45_05695	COG1846	Transcriptional regulator
L2Z45_05700	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z45_05700	COG1902	pentaerythritol trinitrate reductase activity
L2Z45_05715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z45_05745	COG1309	transcriptional regulator
L2Z45_05755	COG1335	isochorismatase
L2Z45_05760	COG0583	DNA-binding transcription factor activity
L2Z45_05770	COG0475	glutathione-regulated potassium exporter activity
L2Z45_05770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z45_05780	COG1473	amidohydrolase
L2Z45_05795	COG4372	Transposase
L2Z45_05815	COG3210	domain, Protein
L2Z45_05845	COG2188	Transcriptional regulator
L2Z45_05860	COG0583	DNA-binding transcription factor activity
L2Z45_05890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z45_05920	COG1566	PFAM secretion protein HlyD family protein
L2Z45_05935	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_05940	COG0129	dihydroxy-acid dehydratase activity
L2Z45_05950	COG0583	DNA-binding transcription factor activity
L2Z45_05955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z45_05965	COG2084	Dehydrogenase
L2Z45_05970	COG2207	Transcriptional regulator
L2Z45_05985	COG1064	alcohol dehydrogenase
L2Z45_05995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z45_06000	COG1120	ATPase activity
L2Z45_06020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z45_06145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z45_06195	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_06210	COG2207	Transcriptional regulator
L2Z45_06220	COG2205	protein histidine kinase activity
L2Z45_06225	COG0745	RESPONSE REGULATOR receiver
L2Z45_06230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z45_06235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z45_06240	COG1538	Outer membrane efflux protein
L2Z45_06250	COG2072	flavoprotein involved in K transport
L2Z45_06270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z45_06290	COG3539	Fimbrial protein
L2Z45_06315	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z45_06325	COG0753	catalase activity
L2Z45_06400	COG1535	isochorismatase
L2Z45_06400	COG3433	isochorismatase activity
L2Z45_06405	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_06410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z45_06415	COG4149	molybdate abc transporter
L2Z45_06420	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z45_06430	COG4638	Rieske (2fe-2S)
L2Z45_06435	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z45_06440	COG0543	2 iron, 2 sulfur cluster binding
L2Z45_06440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z45_06465	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_06480	COG2207	Transcriptional regulator
L2Z45_06485	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_06490	COG2610	gluconate transmembrane transporter activity
L2Z45_06500	COG0583	DNA-binding transcription factor activity
L2Z45_06510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z45_06515	COG2031	fatty acid transporter
L2Z45_06520	COG0183	Belongs to the thiolase family
L2Z45_06525	COG0583	DNA-binding transcription factor activity
L2Z45_06530	COG0583	DNA-binding transcription factor activity
L2Z45_06545	COG1027	Aspartate ammonia-lyase
L2Z45_06555	COG0477	Major facilitator Superfamily
L2Z45_06575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z45_06580	COG4521	taurine ABC transporter
L2Z45_06595	COG2188	Transcriptional regulator
L2Z45_06605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z45_06610	COG1733	regulation of RNA biosynthetic process
L2Z45_06615	COG2207	Transcriptional regulator
L2Z45_06615	COG3708	Transcriptional regulator
L2Z45_06630	COG0730	response to heat
L2Z45_06645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z45_06645	COG3453	Protein conserved in bacteria
L2Z45_06655	COG3781	membrane
L2Z45_06660	COG1063	alcohol dehydrogenase
L2Z45_06670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z45_06675	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z45_06680	COG0022	dehydrogenase e1 component
L2Z45_06685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z45_06690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z45_06705	COG3706	GGDEF domain
L2Z45_06720	COG0133	tryptophan synthase activity
L2Z45_06730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z45_06765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z45_06790	COG2226	methyltransferase
L2Z45_06845	COG0842	Transport permease protein
L2Z45_06850	COG0842	Transport permease protein
L2Z45_06855	COG1131	(ABC) transporter
L2Z45_06870	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z45_06875	COG4773	Receptor
L2Z45_06895	COG0730	response to heat
L2Z45_06900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z45_06920	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z45_06935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z45_06975	COG4264	IucA IucC family
L2Z45_06980	COG4264	IucA IucC family
L2Z45_07000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z45_07015	COG1960	acyl-CoA dehydrogenase activity
L2Z45_07020	COG1960	acyl-CoA dehydrogenase activity
L2Z45_07025	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z45_07030	COG2207	Transcriptional regulator
L2Z45_07035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z45_07040	COG0776	regulation of translation
L2Z45_07065	COG0822	iron-sulfur transferase activity
L2Z45_07070	COG0316	Belongs to the HesB IscA family
L2Z45_07100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z45_07120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z45_07125	COG0702	epimerase
L2Z45_07160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z45_07170	COG0339	signal peptide processing
L2Z45_07220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z45_07340	COG5484	DNA packaging
L2Z45_07340	COG3728	DNA packaging
L2Z45_07440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z45_07470	COG0776	regulation of translation
L2Z45_07535	COG0084	hydrolase, TatD family'
L2Z45_07555	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z45_07560	COG1132	(ABC) transporter
L2Z45_07570	COG0811	peptide transport
L2Z45_07575	COG1475	DNA binding
L2Z45_07580	COG1192	Involved in chromosome partitioning
L2Z45_07590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z45_07605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z45_07610	COG0191	fructose-bisphosphate aldolase activity
L2Z45_07630	COG0424	maF-like protein
L2Z45_07635	COG2850	peptidyl-arginine hydroxylation
L2Z45_07645	COG0640	Transcriptional regulator
L2Z45_07655	COG3619	membrane
L2Z45_07660	COG3122	Protein conserved in bacteria
L2Z45_07665	COG1132	(ABC) transporter
L2Z45_07685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z45_07700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z45_07710	COG0506	proline dehydrogenase activity
L2Z45_07710	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z45_07710	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z45_07715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z45_07730	COG3698	Phosphodiester glycosidase
L2Z45_07740	COG2353	YceI-like domain
L2Z45_07750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z45_07800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z45_07800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z45_07825	COG3539	Fimbrial protein
L2Z45_07830	COG3121	Chaperone
L2Z45_07855	COG0697	spore germination
L2Z45_07865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z45_07875	COG0583	DNA-binding transcription factor activity
L2Z45_07905	COG1309	transcriptional regulator
L2Z45_07920	COG1522	sequence-specific DNA binding
L2Z45_07930	COG1126	abc transporter atp-binding protein
L2Z45_07935	COG0765	amino acid transport
L2Z45_07940	COG0765	amino acid transport
L2Z45_07970	COG1464	Belongs to the NlpA lipoprotein family
L2Z45_07980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z45_07985	COG2011	ABC-type metal ion transport system permease component
L2Z45_07990	COG0012	GTP binding
L2Z45_08015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z45_08055	COG0386	Belongs to the glutathione peroxidase family
L2Z45_08065	COG0436	Aminotransferase
L2Z45_08105	COG3634	alkyl hydroperoxide reductase activity
L2Z45_08120	COG0583	DNA-binding transcription factor activity
L2Z45_08125	COG0798	PFAM Bile acid sodium symporter
L2Z45_08130	COG0640	Transcriptional regulator
L2Z45_08145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z45_08155	COG0583	DNA-binding transcription factor activity
L2Z45_08165	COG1953	Uracil, thiamine, allantoin
L2Z45_08175	COG2175	clavaminate synthase activity
L2Z45_08180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z45_08185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z45_08190	COG4521	taurine ABC transporter
L2Z45_08200	COG0477	Major facilitator Superfamily
L2Z45_08220	COG1271	oxidase subunit
L2Z45_08225	COG1294	oxidase, subunit
L2Z45_08235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z45_08255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z45_08275	COG3052	prosthetic group binding
L2Z45_08280	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z45_08290	COG2814	Major facilitator Superfamily
L2Z45_08310	COG1346	cytolysis
L2Z45_08320	COG0583	DNA-binding transcription factor activity
L2Z45_08325	COG0625	glutathione transferase activity
L2Z45_08330	COG0625	glutathione transferase activity
L2Z45_08335	COG0583	DNA-binding transcription factor activity
L2Z45_08350	COG1045	serine acetyltransferase
L2Z45_08355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z45_08360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z45_08370	COG1280	lysine exporter protein (LysE YggA)
L2Z45_08385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z45_08390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z45_08395	COG1126	abc transporter atp-binding protein
L2Z45_08400	COG0765	amino acid transport
L2Z45_08405	COG0765	amino acid transport
L2Z45_08425	COG0784	Response regulator, receiver
L2Z45_08425	COG2205	protein histidine kinase activity
L2Z45_08445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z45_08465	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_08515	COG0583	DNA-binding transcription factor activity
L2Z45_08535	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z45_08540	COG1309	transcriptional regulator
L2Z45_08545	COG1960	acyl-CoA dehydrogenase activity
L2Z45_08550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z45_08555	COG1024	Enoyl-CoA hydratase
L2Z45_08560	COG4770	biotin carboxylase activity
L2Z45_08570	COG0583	DNA-binding transcription factor activity
L2Z45_08585	COG1960	acyl-CoA dehydrogenase activity
L2Z45_08595	COG2814	Major facilitator Superfamily
L2Z45_08605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z45_08610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z45_08615	COG2814	Major facilitator Superfamily
L2Z45_08620	COG1960	acyl-CoA dehydrogenase activity
L2Z45_08625	COG1024	Enoyl-CoA hydratase
L2Z45_08630	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_08635	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z45_08640	COG0183	Belongs to the thiolase family
L2Z45_08650	COG2814	Major facilitator Superfamily
L2Z45_08660	COG1024	Enoyl-CoA hydratase
L2Z45_08675	COG1960	acyl-CoA dehydrogenase activity
L2Z45_08680	COG2814	Major facilitator Superfamily
L2Z45_08685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z45_08690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z45_08705	COG3842	ATPase activity
L2Z45_08710	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z45_08720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z45_08725	COG1414	Transcriptional regulator
L2Z45_08735	COG0583	DNA-binding transcription factor activity
L2Z45_08740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z45_08745	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_08755	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z45_08765	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_08770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z45_08775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z45_08780	COG2267	carboxylic ester hydrolase activity
L2Z45_08800	COG3038	cytochrome b561
L2Z45_08805	COG0753	catalase activity
L2Z45_08840	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z45_08850	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z45_08855	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z45_08860	COG0183	Belongs to the thiolase family
L2Z45_08865	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z45_08870	COG1024	Enoyl-CoA hydratase
L2Z45_08875	COG1024	Enoyl-CoA hydratase
L2Z45_08880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z45_08885	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z45_08890	COG3396	Phenylacetate-CoA oxygenase
L2Z45_08895	COG3460	Phenylacetate-CoA oxygenase
L2Z45_08900	COG3396	Phenylacetate-CoA oxygenase
L2Z45_08905	COG2030	dehydratase
L2Z45_08905	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_08910	COG1760	l-serine dehydratase
L2Z45_08915	COG0531	amino acid
L2Z45_08920	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_08935	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z45_08945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z45_08965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z45_08975	COG0789	Transcriptional regulator
L2Z45_08985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z45_09000	COG2807	transmembrane transport
L2Z45_09005	COG0590	tRNA wobble adenosine to inosine editing
L2Z45_09125	COG1116	anion transmembrane transporter activity
L2Z45_09130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z45_09140	COG0864	Transcriptional regulator
L2Z45_09160	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z45_09165	COG0439	Biotin carboxylase
L2Z45_09180	COG1063	alcohol dehydrogenase
L2Z45_09190	COG1309	transcriptional regulator
L2Z45_09210	COG0038	chloride channel
L2Z45_09215	COG4770	biotin carboxylase activity
L2Z45_09235	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z45_09240	COG0583	DNA-binding transcription factor activity
L2Z45_09280	COG4372	Transposase
L2Z45_09320	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z45_09340	COG2814	Major facilitator Superfamily
L2Z45_09355	COG1560	Kdo2-lipid A biosynthetic process
L2Z45_09365	COG5006	permease, DMT superfamily
L2Z45_09370	COG1522	sequence-specific DNA binding
L2Z45_09385	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z45_09395	COG4122	O-methyltransferase activity
L2Z45_09440	COG4372	Transposase
L2Z45_09450	COG1137	ATPase activity
L2Z45_09455	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z45_09465	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z45_09470	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z45_09470	COG0517	IMP dehydrogenase activity
L2Z45_09505	COG2814	Major facilitator Superfamily
L2Z45_09540	COG1278	Cold shock
L2Z45_09545	COG1280	lysine exporter protein (LysE YggA)
L2Z45_09575	COG1570	exodeoxyribonuclease VII activity
L2Z45_09625	COG0583	DNA-binding transcription factor activity
L2Z45_09635	COG4638	Rieske (2fe-2S)
L2Z45_09640	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z45_09645	COG0543	2 iron, 2 sulfur cluster binding
L2Z45_09645	COG0633	Ferredoxin
L2Z45_09650	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_09655	COG3135	benzoate transporter
L2Z45_09660	COG2814	Major facilitator Superfamily
L2Z45_09675	COG1643	Atp-dependent helicase
L2Z45_09680	COG0450	alkyl hydroperoxide reductase
L2Z45_09690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z45_09700	COG3634	alkyl hydroperoxide reductase activity
L2Z45_09720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z45_09725	COG0625	glutathione transferase activity
L2Z45_09735	COG2885	chlorophyll binding
L2Z45_09770	COG0542	response to heat
L2Z45_09785	COG1765	OsmC-like protein
L2Z45_09800	COG0667	Aldo Keto reductase
L2Z45_09815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z45_09825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z45_09835	COG0527	aspartate kinase activity
L2Z45_09845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z45_09855	COG3038	cytochrome b561
L2Z45_09860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z45_09865	COG2252	PERMEase
L2Z45_09875	COG2072	flavoprotein involved in K transport
L2Z45_09890	COG1741	Belongs to the pirin family
L2Z45_09895	COG1309	transcriptional regulator
L2Z45_09905	COG0300	oxidoreductase activity
L2Z45_10025	COG2186	Transcriptional regulator
L2Z45_10030	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_10040	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z45_10045	COG2271	Major facilitator Superfamily
L2Z45_10050	COG2721	sulfolactate sulfo-lyase activity
L2Z45_10055	COG0697	spore germination
L2Z45_10070	COG1113	amino acid transport
L2Z45_10090	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_10110	COG0531	amino acid
L2Z45_10120	COG1113	amino acid transport
L2Z45_10160	COG3209	COG3209 Rhs family protein
L2Z45_10190	COG4269	membrane
L2Z45_10205	COG1902	pentaerythritol trinitrate reductase activity
L2Z45_10205	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z45_10215	COG2203	Gaf domain
L2Z45_10215	COG3706	GGDEF domain
L2Z45_10215	COG4251	negative regulation of phosphorylation
L2Z45_10215	COG5001	Diguanylate cyclase
L2Z45_10225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z45_10245	COG4172	Belongs to the ABC transporter superfamily
L2Z45_10250	COG4239	(ABC) transporter, permease
L2Z45_10255	COG4174	ABC transporter (Permease)
L2Z45_10270	COG1388	LysM domain
L2Z45_10270	COG0741	lytic transglycosylase activity
L2Z45_10270	COG1388	LysM domain
L2Z45_10270	COG0741	lytic transglycosylase activity
L2Z45_10275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z45_10315	COG0583	DNA-binding transcription factor activity
L2Z45_10320	COG1279	arginine transmembrane transporter activity
L2Z45_10340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z45_10345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z45_10350	COG0006	proline dipeptidase activity
L2Z45_10400	COG4372	Transposase
L2Z45_10405	COG2194	sulfuric ester hydrolase activity
L2Z45_10450	COG0739	heme binding
L2Z45_10775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z45_10800	COG3384	dioxygenase
L2Z45_10810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z45_10815	COG2878	Part of a membrane complex involved in electron transport
L2Z45_10820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z45_10845	COG0768	penicillin binding
L2Z45_10850	COG0742	ribosomal rna small subunit methyltransferase
L2Z45_10865	COG0830	nickel cation binding
L2Z45_10875	COG0804	urea catabolic process
L2Z45_10915	COG1253	flavin adenine dinucleotide binding
L2Z45_10920	COG2851	Citrate transporter
L2Z45_10970	COG1773	rubredoxin
L2Z45_10975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z45_10985	COG0583	DNA-binding transcription factor activity
L2Z45_11010	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z45_11015	COG4181	ATPase activity
L2Z45_11060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z45_11080	COG0306	phosphate transporter
L2Z45_11090	COG3958	Transketolase
L2Z45_11095	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z45_11100	COG2271	Major facilitator Superfamily
L2Z45_11105	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_11110	COG0583	DNA-binding transcription factor activity
L2Z45_11125	COG2223	nitrite transmembrane transporter activity
L2Z45_11130	COG2207	Transcriptional regulator
L2Z45_11135	COG2066	Belongs to the glutaminase family
L2Z45_11140	COG0242	peptide deformylase activity
L2Z45_11145	COG0477	Major facilitator Superfamily
L2Z45_11155	COG0028	Belongs to the TPP enzyme family
L2Z45_11170	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_11175	COG2267	carboxylic ester hydrolase activity
L2Z45_11185	COG2271	Major facilitator Superfamily
L2Z45_11190	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z45_11200	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_11220	COG1414	Transcriptional regulator
L2Z45_11235	COG1024	Enoyl-CoA hydratase
L2Z45_11245	COG1215	transferase activity, transferring glycosyl groups
L2Z45_11250	COG0726	polysaccharide deacetylase
L2Z45_11250	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z45_11260	COG4681	YaeQ
L2Z45_11270	COG0523	cobalamin synthesis protein
L2Z45_11280	COG1607	acyl-coa hydrolase
L2Z45_11290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z45_11295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z45_11300	COG1309	transcriptional regulator
L2Z45_11325	COG2040	homocysteine
L2Z45_11330	COG0531	amino acid
L2Z45_11385	COG1595	DNA-templated transcription, initiation
L2Z45_11395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z45_11400	COG0477	Major facilitator Superfamily
L2Z45_11420	COG0084	hydrolase, TatD family'
L2Z45_11445	COG2826	transposase and inactivated derivatives, IS30 family
L2Z45_11480	COG0629	single-stranded DNA binding
L2Z45_11535	COG0582	viral genome integration into host DNA
L2Z45_11640	COG0592	DNA-directed DNA polymerase activity
L2Z45_11680	COG2026	Addiction module toxin, RelE StbE family
L2Z45_11885	COG1484	DNA-dependent DNA replication
L2Z45_11980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z45_12050	COG0405	Gamma-glutamyltransferase
L2Z45_12055	COG2814	Major facilitator Superfamily
L2Z45_12065	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z45_12080	COG1090	epimerase
L2Z45_12100	COG0420	3'-5' exonuclease activity
L2Z45_12125	COG0735	belongs to the Fur family
L2Z45_12130	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z45_12150	COG0121	glutamine amidotransferase
L2Z45_12165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z45_12175	COG0210	DNA helicase
L2Z45_12180	COG2885	chlorophyll binding
L2Z45_12185	COG0204	Acyl-transferase
L2Z45_12200	COG2894	cell division
L2Z45_12215	COG1280	lysine exporter protein (LysE YggA)
L2Z45_12220	COG1674	ftsk spoiiie
L2Z45_12220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z45_12225	COG0492	ferredoxin-NADP+ reductase activity
L2Z45_12230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z45_12240	COG0456	acetyltransferase
L2Z45_12285	COG1981	membrane
L2Z45_12300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z45_12300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z45_12320	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_12330	COG0657	acetylesterase activity
L2Z45_12340	COG0473	3-isopropylmalate dehydrogenase activity
L2Z45_12345	COG0583	DNA-binding transcription factor activity
L2Z45_12365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z45_12390	COG0564	pseudouridine synthase activity
L2Z45_12400	COG0358	DNA primase activity
L2Z45_12415	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z45_12445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z45_12475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z45_12485	COG0351	phosphomethylpyrimidine kinase
L2Z45_12485	COG0352	thiamine-phosphate diphosphorylase activity
L2Z45_12485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z45_12490	COG1652	LysM domain
L2Z45_12515	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z45_12520	COG3101	peptidyl-lysine hydroxylation
L2Z45_12525	COG0009	L-threonylcarbamoyladenylate synthase
L2Z45_12530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z45_12535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z45_12550	COG4106	trans-aconitate 2-methyltransferase activity
L2Z45_12565	COG0596	Alpha beta hydrolase
L2Z45_12565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z45_12565	COG2226	methyltransferase
L2Z45_12575	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z45_12580	COG2223	nitrite transmembrane transporter activity
L2Z45_12600	COG1196	nuclear chromosome segregation
L2Z45_12610	COG0730	response to heat
L2Z45_12625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z45_12635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z45_12685	COG0489	protein tyrosine kinase activity
L2Z45_12695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z45_12695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z45_12725	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z45_12730	COG2081	HI0933 family
L2Z45_12740	COG0668	transmembrane transport
L2Z45_12760	COG0583	DNA-binding transcription factor activity
L2Z45_12785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z45_12790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z45_12820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z45_12860	COG0745	RESPONSE REGULATOR receiver
L2Z45_12880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z45_12890	COG0384	phenazine biosynthesis protein PhzF
L2Z45_12910	COG2826	transposase and inactivated derivatives, IS30 family
L2Z45_12925	COG1309	transcriptional regulator
L2Z45_12935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z45_12950	COG0583	DNA-binding transcription factor activity
L2Z45_12980	COG0583	DNA-binding transcription factor activity
L2Z45_12995	COG0583	DNA-binding transcription factor activity
L2Z45_13000	COG1053	succinate dehydrogenase
L2Z45_13010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z45_13015	COG2814	Major facilitator Superfamily
L2Z45_13020	COG1960	acyl-CoA dehydrogenase activity
L2Z45_13025	COG0583	DNA-binding transcription factor activity
L2Z45_13030	COG1063	alcohol dehydrogenase
L2Z45_13060	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z45_13065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z45_13070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z45_13085	COG3667	copper resistance
L2Z45_13090	COG2132	Multicopper oxidase
L2Z45_13100	COG0561	phosphatase activity
L2Z45_13105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z45_13115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L2Z45_13130	COG1214	PFAM Peptidase M22, glycoprotease
L2Z45_13180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z45_13190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z45_13195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z45_13200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z45_13260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z45_13270	COG1846	Transcriptional regulator
L2Z45_13275	COG1764	response to oxidative stress
L2Z45_13315	COG0037	tRNA processing
L2Z45_13325	COG0248	Ppx GppA phosphatase
L2Z45_13355	COG0072	phenylalanine-tRNA ligase activity
L2Z45_13405	COG1238	metal cluster binding
L2Z45_13410	COG0625	glutathione transferase activity
L2Z45_13425	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z45_13430	COG3028	Belongs to the UPF0307 family
L2Z45_13435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z45_13455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z45_13460	COG0617	tRNA 3'-terminal CCA addition
L2Z45_13465	COG1555	photosystem II stabilization
L2Z45_13470	COG3956	TIGRFAM MazG family protein
L2Z45_13480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z45_13500	COG0784	Response regulator, receiver
L2Z45_13500	COG5002	protein histidine kinase activity
L2Z45_13500	COG2205	protein histidine kinase activity
L2Z45_13505	COG1024	Enoyl-CoA hydratase
L2Z45_13510	COG2084	Dehydrogenase
L2Z45_13515	COG3622	Belongs to the hyi family
L2Z45_13545	COG0697	spore germination
L2Z45_13555	COG2814	Major facilitator Superfamily
L2Z45_13560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z45_13570	COG0583	DNA-binding transcription factor activity
L2Z45_13580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z45_13590	COG0084	hydrolase, TatD family'
L2Z45_13605	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z45_13635	COG0440	acetolactate synthase activity
L2Z45_13640	COG0028	Belongs to the TPP enzyme family
L2Z45_13665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z45_13670	COG0577	efflux transmembrane transporter activity
L2Z45_13670	COG1136	(ABC) transporter
L2Z45_13675	COG1538	Outer membrane efflux protein
L2Z45_13690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z45_13695	COG1162	GTPase activity
L2Z45_13705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z45_13745	COG1426	Protein conserved in bacteria
L2Z45_13780	COG0793	Belongs to the peptidase S41A family
L2Z45_13795	COG2267	carboxylic ester hydrolase activity
L2Z45_13805	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_13810	COG3265	gluconokinase activity
L2Z45_13820	COG0800	Aldolase
L2Z45_13830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z45_13835	COG0857	belongs to the CobB CobQ family
L2Z45_13835	COG0280	phosphate acetyltransferase
L2Z45_13840	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z45_13840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z45_13860	COG0740	serine-type endopeptidase activity
L2Z45_13870	COG4774	siderophore transport
L2Z45_13880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z45_13890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z45_13890	COG2813	Specifically methylates the guanine in position
L2Z45_13990	COG0788	formyltetrahydrofolate deformylase activity
L2Z45_14015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z45_14015	COG4651	solute:proton antiporter activity
L2Z45_14035	COG0724	RNA recognition motif
L2Z45_14040	COG0210	DNA helicase
L2Z45_14065	COG1733	regulation of RNA biosynthetic process
L2Z45_14075	COG2900	Belongs to the SlyX family
L2Z45_14080	COG0488	(ABC) transporter
L2Z45_14085	COG1280	lysine exporter protein (LysE YggA)
L2Z45_14090	COG1560	Kdo2-lipid A biosynthetic process
L2Z45_14100	COG1301	dicarboxylic acid transport
L2Z45_14155	COG0473	3-isopropylmalate dehydrogenase activity
L2Z45_14210	COG0583	DNA-binding transcription factor activity
L2Z45_14220	COG0625	glutathione transferase activity
L2Z45_14225	COG2378	regulation of single-species biofilm formation
L2Z45_14230	COG0546	phosphoglycolate phosphatase activity
L2Z45_14245	COG1530	ribonuclease E activity
L2Z45_14250	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z45_14265	COG0583	DNA-binding transcription factor activity
L2Z45_14270	COG4221	oxidoreductase activity
L2Z45_14275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z45_14285	COG0534	Mate efflux family protein
L2Z45_14300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z45_14325	COG0493	'glutamate synthase
L2Z45_14325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z45_14335	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z45_14340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z45_14355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z45_14365	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z45_14365	COG0644	oxidoreductase
L2Z45_14375	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z45_14380	COG4535	Mg2 and Co2 transporter CorC
L2Z45_14390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z45_14410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z45_14415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z45_14415	COG0475	glutathione-regulated potassium exporter activity
L2Z45_14430	COG0484	heat shock protein binding
L2Z45_14435	COG0789	Transcriptional regulator
L2Z45_14440	COG0598	Magnesium transport protein CorA
L2Z45_14455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z45_14460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z45_14465	COG1074	ATP-dependent DNA helicase activity
L2Z45_14470	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z45_14490	COG2226	methyltransferase
L2Z45_14505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z45_14510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z45_14525	COG2111	Na H antiporter
L2Z45_14525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z45_14530	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z45_14535	COG0651	ATP synthesis coupled electron transport
L2Z45_14540	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z45_14545	COG2212	antiporter activity
L2Z45_14550	COG1320	monovalent cation:proton antiporter activity
L2Z45_14565	COG0195	Participates in both transcription termination and antitermination
L2Z45_14620	COG0237	dephospho-CoA kinase activity
L2Z45_14630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z45_14645	COG0497	DNA recombination
L2Z45_14655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z45_14685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z45_14685	COG2169	Transcriptional regulator
L2Z45_14690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z45_14750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z45_14765	COG0326	Molecular chaperone. Has ATPase activity
L2Z45_14780	COG2056	Na+-H+ antiporter family
L2Z45_14880	COG0546	phosphoglycolate phosphatase activity
L2Z45_14885	COG1716	ATPase activity
L2Z45_14930	COG0181	hydroxymethylbilane synthase activity
L2Z45_14940	COG3275	phosphorelay sensor kinase activity
L2Z45_14960	COG1538	Outer membrane efflux protein
L2Z45_14965	COG0697	spore germination
L2Z45_14990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z45_14995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z45_15000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z45_15005	COG0772	Belongs to the SEDS family
L2Z45_15030	COG4974	Belongs to the 'phage' integrase family
L2Z45_15035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z45_15045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z45_15055	COG2197	response regulator
L2Z45_15070	COG0793	Belongs to the peptidase S41A family
L2Z45_15075	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z45_15080	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z45_15120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z45_15120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z45_15130	COG0004	ammonium transporteR
L2Z45_15150	COG0347	Belongs to the P(II) protein family
L2Z45_15235	COG0789	Transcriptional regulator
L2Z45_15260	COG0659	secondary active sulfate transmembrane transporter activity
L2Z45_15330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z45_15350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z45_15365	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z45_15375	COG0477	Major facilitator Superfamily
L2Z45_15380	COG2860	membrane
L2Z45_15385	COG3012	SEC-C Motif Domain Protein
L2Z45_15390	COG1253	flavin adenine dinucleotide binding
L2Z45_15400	COG0477	Major facilitator Superfamily
L2Z45_15410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z45_15450	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z45_15460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z45_15530	COG0758	DNA mediated transformation
L2Z45_15540	COG0697	spore germination
L2Z45_15545	COG1309	transcriptional regulator
L2Z45_15560	COG0386	Belongs to the glutathione peroxidase family
L2Z45_15625	COG1121	(ABC) transporter
L2Z45_15630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z45_15635	COG1280	lysine exporter protein (LysE YggA)
L2Z45_15640	COG2837	iron assimilation
L2Z45_15645	COG0281	malic enzyme
L2Z45_15690	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z45_15690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z45_15695	COG4399	Belongs to the UPF0754 family
L2Z45_15700	COG2259	Doxx family
L2Z45_15705	COG0586	Pfam SNARE associated Golgi protein
L2Z45_15720	COG1192	Involved in chromosome partitioning
L2Z45_15730	COG0271	Belongs to the BolA IbaG family
L2Z45_15750	COG2267	carboxylic ester hydrolase activity
L2Z45_15770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z45_15770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z45_15770	COG3321	synthase
L2Z45_15770	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z45_15775	COG1960	acyl-CoA dehydrogenase activity
L2Z45_15785	COG2197	response regulator
L2Z45_15795	COG3916	Acyl-homoserine-lactone synthase
L2Z45_15800	COG0477	Major facilitator Superfamily
L2Z45_15805	COG1024	Enoyl-CoA hydratase
L2Z45_15810	COG1024	Enoyl-CoA hydratase
L2Z45_15815	COG1960	acyl-CoA dehydrogenase activity
L2Z45_15820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z45_15840	COG1113	amino acid transport
L2Z45_15845	COG1113	amino acid transport
L2Z45_15850	COG0251	oxidation-reduction process
L2Z45_15890	COG0564	pseudouridine synthase activity
L2Z45_15940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z45_15955	COG1802	Transcriptional regulator
L2Z45_15960	COG1448	Aminotransferase
L2Z45_15965	COG0277	FAD linked oxidase domain protein
L2Z45_15975	COG2186	Transcriptional regulator
L2Z45_15985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z45_15990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z45_16005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z45_16015	COG0110	maltose O-acetyltransferase activity
L2Z45_16020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z45_16050	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z45_16055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z45_16060	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z45_16100	COG0728	peptidoglycan biosynthetic process
L2Z45_16105	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z45_16160	COG0546	phosphoglycolate phosphatase activity
L2Z45_16165	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z45_16185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z45_16190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z45_16195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z45_16200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z45_16205	COG1116	anion transmembrane transporter activity
L2Z45_16210	COG1309	transcriptional regulator
L2Z45_16215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z45_16225	COG0196	riboflavin kinase activity
L2Z45_16230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z45_16240	COG1047	Peptidyl-prolyl cis-trans
L2Z45_16280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z45_16285	COG0657	acetylesterase activity
L2Z45_16305	COG0583	DNA-binding transcription factor activity
L2Z45_16335	COG2951	lytic endotransglycosylase activity
L2Z45_16340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z45_16355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z45_16365	COG0671	phosphoesterase, PA-phosphatase related
L2Z45_16370	COG0861	Integral membrane protein TerC family
L2Z45_16380	COG0754	glutathionylspermidine amidase activity
L2Z45_16390	COG0402	S-adenosylhomocysteine deaminase activity
L2Z45_16405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z45_16410	COG1230	cation diffusion facilitator family transporter
L2Z45_16425	COG0706	membrane insertase activity
L2Z45_16450	COG0592	DNA-directed DNA polymerase activity
L2Z45_16460	COG0187	DNA topoisomerase II activity
L2Z45_16470	COG0586	Pfam SNARE associated Golgi protein
L2Z45_16475	COG0488	(ABC) transporter
L2Z45_16500	COG0596	Alpha beta hydrolase
L2Z45_16505	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z45_16510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z45_16550	COG0733	neurotransmitter:sodium symporter activity
L2Z45_16585	COG0583	DNA-binding transcription factor activity
L2Z45_16590	COG2233	PERMEase
L2Z45_16605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z45_16640	COG2814	Major facilitator Superfamily
L2Z45_16645	COG0656	L-ascorbic acid biosynthetic process
L2Z45_16650	COG0583	DNA-binding transcription factor activity
L2Z45_16680	COG1064	alcohol dehydrogenase
L2Z45_16685	COG2818	Glycosylase
L2Z45_16700	COG1194	a g-specific adenine glycosylase
L2Z45_16720	COG2983	Belongs to the UPF0260 family
L2Z45_16725	COG2133	pyrroloquinoline quinone binding
L2Z45_16730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z45_16735	COG2116	formate transmembrane transporter activity
L2Z45_16755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z45_16760	COG1335	isochorismatase
L2Z45_16765	COG0385	Bile acid
L2Z45_16770	COG0534	Mate efflux family protein
L2Z45_16775	COG1683	Conserved Protein
L2Z45_16795	COG0625	glutathione transferase activity
L2Z45_16805	COG1113	amino acid transport
L2Z45_16815	COG0523	cobalamin synthesis protein
L2Z45_16825	COG2188	Transcriptional regulator
L2Z45_16855	COG0010	Belongs to the arginase family
L2Z45_16870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z45_16875	COG2826	transposase and inactivated derivatives, IS30 family
L2Z45_16880	COG2205	protein histidine kinase activity
L2Z45_16890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z45_16900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z45_16905	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z45_16990	COG0534	Mate efflux family protein
L2Z45_16995	COG0436	Aminotransferase
L2Z45_17000	COG2733	membrane
L2Z45_17015	COG2918	glutathione biosynthetic process
L2Z45_17070	COG3150	esterase
L2Z45_17080	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z45_17090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z45_17100	COG2233	PERMEase
L2Z45_17105	COG2351	hydroxyisourate hydrolase activity
L2Z45_17140	COG3706	GGDEF domain
L2Z45_17155	COG1393	Belongs to the ArsC family
L2Z45_17160	COG0708	Exodeoxyribonuclease III
L2Z45_17180	COG0189	ligase activity
L2Z45_17200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z45_17210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z45_17225	COG4942	peptidase
L2Z45_17235	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z45_17245	COG2119	membrane
L2Z45_17250	COG4774	siderophore transport
L2Z45_17255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z45_17255	COG0426	domain, Protein
L2Z45_17280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z45_17300	COG1902	pentaerythritol trinitrate reductase activity
L2Z45_17305	COG1519	Transferase
L2Z45_17310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z45_17315	COG0668	transmembrane transport
L2Z45_17325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z45_17330	COG1335	isochorismatase
L2Z45_17335	COG1522	sequence-specific DNA binding
L2Z45_17360	COG0784	Response regulator, receiver
L2Z45_17360	COG2198	Histidine kinase
L2Z45_17360	COG2205	protein histidine kinase activity
L2Z45_17365	COG3162	membrane
L2Z45_17370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z45_17380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z45_17395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z45_17400	COG1309	transcriptional regulator
L2Z45_17420	COG0352	thiamine-phosphate diphosphorylase activity
L2Z45_17420	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z45_17420	COG0351	phosphomethylpyrimidine kinase
L2Z45_17430	COG2814	Major facilitator Superfamily
L2Z45_17445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z45_17455	COG1113	amino acid transport
L2Z45_17465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z45_17470	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_17480	COG1335	isochorismatase
L2Z45_17510	COG2814	Major facilitator Superfamily
L2Z45_17515	COG0583	DNA-binding transcription factor activity
L2Z45_17535	COG0667	Aldo Keto reductase
L2Z45_17555	COG1733	regulation of RNA biosynthetic process
L2Z45_17570	COG1733	regulation of RNA biosynthetic process
L2Z45_17575	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z45_17585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2Z45_17645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z45_17685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z45_17715	COG0427	acetyl-CoA hydrolase
L2Z45_17740	COG0659	secondary active sulfate transmembrane transporter activity
L2Z45_17745	COG4221	oxidoreductase activity
L2Z45_17750	COG2873	o-acetylhomoserine
L2Z45_17755	COG0488	(ABC) transporter
L2Z45_17820	COG0833	amino acid
L2Z45_17865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z45_17870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z45_17885	COG2226	methyltransferase
L2Z45_17935	COG0069	glutamate synthase activity
L2Z45_17935	COG0067	glutamate synthase
L2Z45_17935	COG0070	glutamate synthase
L2Z45_17940	COG0493	'glutamate synthase
L2Z45_17950	COG1704	LemA family
L2Z45_17955	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z45_17970	COG3307	-O-antigen
L2Z45_17990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z45_18005	COG0194	GDP metabolic process
L2Z45_18055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z45_18075	COG5380	lipid catabolic process
L2Z45_18080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z45_18105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z45_18110	COG0277	FAD linked oxidase domain protein
L2Z45_18120	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z45_18125	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z45_18140	COG1289	transmembrane transporter activity
L2Z45_18150	COG0628	permease
L2Z45_18155	COG1192	Involved in chromosome partitioning
L2Z45_18190	COG0833	amino acid
L2Z45_18195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z45_18200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z45_18210	COG1012	belongs to the aldehyde dehydrogenase family
L2Z45_18250	COG0583	DNA-binding transcription factor activity
L2Z45_18300	COG0517	IMP dehydrogenase activity
L2Z45_18305	COG1983	PspC domain protein
L2Z45_18315	COG1960	acyl-CoA dehydrogenase activity
L2Z45_18330	COG0408	coproporphyrinogen oxidase activity
L2Z45_18350	COG0513	Belongs to the DEAD box helicase family
L2Z45_18360	COG1127	ABC transporter
L2Z45_18365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z45_18375	COG2854	intermembrane phospholipid transfer
L2Z45_18385	COG0598	Magnesium transport protein CorA
L2Z45_18395	COG0494	nUDIX hydrolase
L2Z45_18400	COG1040	competence protein
L2Z45_18405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z45_18425	COG1946	Acyl-CoA thioesterase
L2Z45_18430	COG1301	dicarboxylic acid transport
L2Z45_18445	COG1959	2 iron, 2 sulfur cluster binding
L2Z45_18450	COG1017	nitric oxide dioxygenase activity
L2Z45_18450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z45_18455	COG0433	COG0433 Predicted ATPase
L2Z45_18460	COG0626	cystathionine gamma-synthase activity
L2Z45_18615	COG1960	acyl-CoA dehydrogenase activity
L2Z45_18620	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z45_18650	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z45_18655	COG0339	signal peptide processing
L2Z45_18660	COG0557	exoribonuclease II activity
L2Z45_18705	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z45_18710	COG2169	Transcriptional regulator
L2Z45_18715	COG0697	spore germination
L2Z45_18720	COG1295	ribonuclease BN
L2Z45_18755	COG1702	phosphate starvation-inducible protein PhoH
L2Z45_18765	COG0741	lytic transglycosylase activity
L2Z45_18765	COG1196	nuclear chromosome segregation
L2Z45_18765	COG0739	heme binding
L2Z45_18795	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z45_18800	COG1183	phosphatidylcholine synthase activity
L2Z45_18860	COG3293	Transposase