locus-tag	class	description
L2Z31_00040	COG0589	response to stress
L2Z31_00045	COG0659	secondary active sulfate transmembrane transporter activity
L2Z31_00105	COG0347	Belongs to the P(II) protein family
L2Z31_00110	COG0004	ammonium transporteR
L2Z31_00120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z31_00120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z31_00165	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z31_00170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z31_00175	COG0793	Belongs to the peptidase S41A family
L2Z31_00190	COG2197	response regulator
L2Z31_00200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z31_00210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z31_00215	COG4974	Belongs to the 'phage' integrase family
L2Z31_00240	COG0772	Belongs to the SEDS family
L2Z31_00245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z31_00250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z31_00255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z31_00280	COG0697	spore germination
L2Z31_00285	COG1538	Outer membrane efflux protein
L2Z31_00305	COG3275	phosphorelay sensor kinase activity
L2Z31_00315	COG0181	hydroxymethylbilane synthase activity
L2Z31_00360	COG1716	ATPase activity
L2Z31_00365	COG0546	phosphoglycolate phosphatase activity
L2Z31_00460	COG0596	Alpha beta hydrolase
L2Z31_00465	COG2056	Na+-H+ antiporter family
L2Z31_00480	COG0326	Molecular chaperone. Has ATPase activity
L2Z31_00495	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z31_00560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z31_00565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z31_00565	COG2169	Transcriptional regulator
L2Z31_00595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z31_00605	COG0497	DNA recombination
L2Z31_00620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z31_00630	COG0237	dephospho-CoA kinase activity
L2Z31_00635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z31_00685	COG0195	Participates in both transcription termination and antitermination
L2Z31_00700	COG1320	monovalent cation:proton antiporter activity
L2Z31_00705	COG2212	antiporter activity
L2Z31_00710	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z31_00715	COG0651	ATP synthesis coupled electron transport
L2Z31_00720	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z31_00725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z31_00725	COG2111	Na H antiporter
L2Z31_00740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z31_00745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z31_00760	COG2226	methyltransferase
L2Z31_00780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z31_00785	COG1074	ATP-dependent DNA helicase activity
L2Z31_00790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z31_00795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z31_00810	COG0598	Magnesium transport protein CorA
L2Z31_00815	COG0789	Transcriptional regulator
L2Z31_00820	COG0484	heat shock protein binding
L2Z31_00830	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z31_00835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z31_00835	COG0475	glutathione-regulated potassium exporter activity
L2Z31_00840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z31_00860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z31_00870	COG4535	Mg2 and Co2 transporter CorC
L2Z31_00875	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z31_00880	COG0644	oxidoreductase
L2Z31_00880	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z31_00890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z31_00905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z31_00910	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z31_00950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z31_00965	COG0534	Mate efflux family protein
L2Z31_00975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z31_00980	COG4221	oxidoreductase activity
L2Z31_00985	COG0583	DNA-binding transcription factor activity
L2Z31_01000	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z31_01005	COG1530	ribonuclease E activity
L2Z31_01015	COG0546	phosphoglycolate phosphatase activity
L2Z31_01020	COG2378	regulation of single-species biofilm formation
L2Z31_01025	COG0625	glutathione transferase activity
L2Z31_01035	COG0583	DNA-binding transcription factor activity
L2Z31_01100	COG0473	3-isopropylmalate dehydrogenase activity
L2Z31_01155	COG1301	dicarboxylic acid transport
L2Z31_01165	COG1560	Kdo2-lipid A biosynthetic process
L2Z31_01170	COG1280	lysine exporter protein (LysE YggA)
L2Z31_01175	COG0488	(ABC) transporter
L2Z31_01180	COG2900	Belongs to the SlyX family
L2Z31_01190	COG1733	regulation of RNA biosynthetic process
L2Z31_01215	COG0210	DNA helicase
L2Z31_01220	COG0724	RNA recognition motif
L2Z31_01240	COG4651	solute:proton antiporter activity
L2Z31_01240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z31_01265	COG0788	formyltetrahydrofolate deformylase activity
L2Z31_01365	COG2813	Specifically methylates the guanine in position
L2Z31_01365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z31_01375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z31_01385	COG4774	siderophore transport
L2Z31_01395	COG0740	serine-type endopeptidase activity
L2Z31_01415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z31_01415	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z31_01420	COG0857	belongs to the CobB CobQ family
L2Z31_01420	COG0280	phosphate acetyltransferase
L2Z31_01425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z31_01435	COG0800	Aldolase
L2Z31_01445	COG3265	gluconokinase activity
L2Z31_01450	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_01460	COG2267	carboxylic ester hydrolase activity
L2Z31_01475	COG0793	Belongs to the peptidase S41A family
L2Z31_01510	COG1426	Protein conserved in bacteria
L2Z31_01555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z31_01565	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z31_01580	COG2986	histidine ammonia-lyase
L2Z31_01620	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_01625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z31_01645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z31_01655	COG1162	GTPase activity
L2Z31_01660	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z31_01675	COG1538	Outer membrane efflux protein
L2Z31_01680	COG1136	(ABC) transporter
L2Z31_01680	COG0577	efflux transmembrane transporter activity
L2Z31_01685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z31_01710	COG0028	Belongs to the TPP enzyme family
L2Z31_01715	COG0440	acetolactate synthase activity
L2Z31_01745	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z31_01760	COG0084	hydrolase, TatD family'
L2Z31_01775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z31_01785	COG0583	DNA-binding transcription factor activity
L2Z31_01795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z31_01800	COG2814	Major facilitator Superfamily
L2Z31_01810	COG0697	spore germination
L2Z31_01840	COG3622	Belongs to the hyi family
L2Z31_01845	COG2084	Dehydrogenase
L2Z31_01850	COG1024	Enoyl-CoA hydratase
L2Z31_01855	COG5002	protein histidine kinase activity
L2Z31_01855	COG0784	Response regulator, receiver
L2Z31_01855	COG2205	protein histidine kinase activity
L2Z31_01875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z31_01885	COG3956	TIGRFAM MazG family protein
L2Z31_01890	COG1555	photosystem II stabilization
L2Z31_01895	COG0617	tRNA 3'-terminal CCA addition
L2Z31_01900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z31_01920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z31_01925	COG3028	Belongs to the UPF0307 family
L2Z31_01930	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z31_01945	COG0625	glutathione transferase activity
L2Z31_01950	COG1238	metal cluster binding
L2Z31_01995	COG0072	phenylalanine-tRNA ligase activity
L2Z31_02025	COG0248	Ppx GppA phosphatase
L2Z31_02035	COG0037	tRNA processing
L2Z31_02075	COG1764	response to oxidative stress
L2Z31_02080	COG1846	Transcriptional regulator
L2Z31_02090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z31_02150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z31_02155	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z31_02160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z31_02220	COG1214	PFAM Peptidase M22, glycoprotease
L2Z31_02245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z31_02250	COG0561	phosphatase activity
L2Z31_02260	COG2132	Multicopper oxidase
L2Z31_02265	COG3667	copper resistance
L2Z31_02280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z31_02285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z31_02290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z31_02320	COG1063	alcohol dehydrogenase
L2Z31_02325	COG0583	DNA-binding transcription factor activity
L2Z31_02330	COG1960	acyl-CoA dehydrogenase activity
L2Z31_02335	COG2814	Major facilitator Superfamily
L2Z31_02340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z31_02350	COG1053	succinate dehydrogenase
L2Z31_02355	COG0583	DNA-binding transcription factor activity
L2Z31_02370	COG0583	DNA-binding transcription factor activity
L2Z31_02400	COG0583	DNA-binding transcription factor activity
L2Z31_02415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z31_02435	COG0384	phenazine biosynthesis protein PhzF
L2Z31_02455	COG4993	Dehydrogenase
L2Z31_02525	COG2205	protein histidine kinase activity
L2Z31_02535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z31_02555	COG0745	RESPONSE REGULATOR receiver
L2Z31_02595	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z31_02625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z31_02630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z31_02650	COG0583	DNA-binding transcription factor activity
L2Z31_02670	COG0668	transmembrane transport
L2Z31_02680	COG2081	HI0933 family
L2Z31_02685	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z31_02715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z31_02715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z31_02725	COG0489	protein tyrosine kinase activity
L2Z31_02775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z31_02785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z31_02800	COG0730	response to heat
L2Z31_02810	COG1196	nuclear chromosome segregation
L2Z31_02830	COG2223	nitrite transmembrane transporter activity
L2Z31_02835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z31_02840	COG1877	trehalose-phosphatase activity
L2Z31_02845	COG0596	Alpha beta hydrolase
L2Z31_02845	COG2226	methyltransferase
L2Z31_02845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z31_02860	COG4106	trans-aconitate 2-methyltransferase activity
L2Z31_02875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z31_02880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z31_02885	COG0009	L-threonylcarbamoyladenylate synthase
L2Z31_02890	COG3101	peptidyl-lysine hydroxylation
L2Z31_02895	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z31_02920	COG1652	LysM domain
L2Z31_02925	COG0351	phosphomethylpyrimidine kinase
L2Z31_02925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z31_02925	COG0352	thiamine-phosphate diphosphorylase activity
L2Z31_02935	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z31_02965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z31_02995	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z31_03010	COG0358	DNA primase activity
L2Z31_03020	COG0564	pseudouridine synthase activity
L2Z31_03045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z31_03065	COG0583	DNA-binding transcription factor activity
L2Z31_03070	COG0473	3-isopropylmalate dehydrogenase activity
L2Z31_03090	COG0657	acetylesterase activity
L2Z31_03100	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_03120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z31_03120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z31_03135	COG1981	membrane
L2Z31_03180	COG0456	acetyltransferase
L2Z31_03190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z31_03195	COG0492	ferredoxin-NADP+ reductase activity
L2Z31_03200	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z31_03200	COG1674	ftsk spoiiie
L2Z31_03205	COG1280	lysine exporter protein (LysE YggA)
L2Z31_03225	COG2894	cell division
L2Z31_03240	COG0204	Acyl-transferase
L2Z31_03245	COG2885	chlorophyll binding
L2Z31_03250	COG0210	DNA helicase
L2Z31_03260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z31_03275	COG0121	glutamine amidotransferase
L2Z31_03295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z31_03300	COG0735	belongs to the Fur family
L2Z31_03325	COG0420	3'-5' exonuclease activity
L2Z31_03345	COG1090	epimerase
L2Z31_03360	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z31_03370	COG2814	Major facilitator Superfamily
L2Z31_03375	COG0405	Gamma-glutamyltransferase
L2Z31_03415	COG0477	Major facilitator Superfamily
L2Z31_03420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z31_03445	COG0531	amino acid
L2Z31_03450	COG2040	homocysteine
L2Z31_03475	COG1309	transcriptional regulator
L2Z31_03480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z31_03485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z31_03495	COG1607	acyl-coa hydrolase
L2Z31_03505	COG0523	cobalamin synthesis protein
L2Z31_03515	COG4681	YaeQ
L2Z31_03525	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z31_03525	COG0726	polysaccharide deacetylase
L2Z31_03530	COG1215	transferase activity, transferring glycosyl groups
L2Z31_03540	COG1024	Enoyl-CoA hydratase
L2Z31_03555	COG1414	Transcriptional regulator
L2Z31_03575	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_03585	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z31_03590	COG2271	Major facilitator Superfamily
L2Z31_03600	COG2267	carboxylic ester hydrolase activity
L2Z31_03605	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_03620	COG0028	Belongs to the TPP enzyme family
L2Z31_03630	COG0477	Major facilitator Superfamily
L2Z31_03635	COG0242	peptide deformylase activity
L2Z31_03640	COG2066	Belongs to the glutaminase family
L2Z31_03645	COG2207	Transcriptional regulator
L2Z31_03650	COG2223	nitrite transmembrane transporter activity
L2Z31_03665	COG0583	DNA-binding transcription factor activity
L2Z31_03670	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_03675	COG2271	Major facilitator Superfamily
L2Z31_03680	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z31_03685	COG3958	Transketolase
L2Z31_03695	COG0306	phosphate transporter
L2Z31_03715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z31_03760	COG4181	ATPase activity
L2Z31_03765	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z31_03790	COG0583	DNA-binding transcription factor activity
L2Z31_03800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z31_03805	COG1773	rubredoxin
L2Z31_03910	COG0488	(ABC) transporter
L2Z31_03915	COG3173	Aminoglycoside phosphotransferase
L2Z31_03925	COG2433	Pfam Transposase IS66
L2Z31_03950	COG1301	dicarboxylic acid transport
L2Z31_03960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z31_03965	COG2011	ABC-type metal ion transport system permease component
L2Z31_03970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z31_03975	COG1464	Belongs to the NlpA lipoprotein family
L2Z31_03980	COG0151	Belongs to the GarS family
L2Z31_03985	COG0138	bifunctional purine biosynthesis protein purh
L2Z31_03990	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z31_04020	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z31_04030	COG1305	Transglutaminase-like
L2Z31_04040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z31_04045	COG0305	Participates in initiation and elongation during chromosome replication
L2Z31_04070	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z31_04080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z31_04085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z31_04110	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z31_04110	COG0726	polysaccharide deacetylase
L2Z31_04115	COG1215	transferase activity, transferring glycosyl groups
L2Z31_04120	COG3658	cytochrome
L2Z31_04130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z31_04145	COG0583	DNA-binding transcription factor activity
L2Z31_04165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z31_04170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z31_04185	COG1960	acyl-CoA dehydrogenase activity
L2Z31_04190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z31_04195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z31_04220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z31_04225	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z31_04235	COG2205	protein histidine kinase activity
L2Z31_04240	COG0745	RESPONSE REGULATOR receiver
L2Z31_04245	COG0174	glutamine synthetase
L2Z31_04265	COG0729	surface antigen
L2Z31_04290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z31_04295	COG2814	Major facilitator Superfamily
L2Z31_04310	COG0583	DNA-binding transcription factor activity
L2Z31_04325	COG1187	pseudouridine synthase activity
L2Z31_04345	COG0802	atpase or kinase
L2Z31_04350	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z31_04360	COG1923	regulation of RNA biosynthetic process
L2Z31_04365	COG0697	spore germination
L2Z31_04380	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z31_04390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z31_04395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z31_04395	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z31_04400	COG4302	ethanolamine ammonia-lyase activity
L2Z31_04405	COG4303	Ethanolamine ammonia lyase large subunit
L2Z31_04410	COG0531	amino acid
L2Z31_04430	COG1454	alcohol dehydrogenase
L2Z31_04435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z31_04445	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z31_04465	COG0308	aminopeptidase N
L2Z31_04475	COG4221	oxidoreductase activity
L2Z31_04485	COG1605	Chorismate mutase
L2Z31_04505	COG1309	transcriptional regulator
L2Z31_04515	COG0668	transmembrane transport
L2Z31_04550	COG4773	Receptor
L2Z31_04570	COG0488	(ABC) transporter
L2Z31_04575	COG0589	response to stress
L2Z31_04600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z31_04610	COG3135	benzoate transporter
L2Z31_04615	COG1522	sequence-specific DNA binding
L2Z31_04625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z31_04630	COG0583	DNA-binding transcription factor activity
L2Z31_04640	COG0183	Belongs to the thiolase family
L2Z31_04650	COG2030	dehydratase
L2Z31_04655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z31_04670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z31_04680	COG0824	Thioesterase
L2Z31_04685	COG1454	alcohol dehydrogenase
L2Z31_04695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z31_04715	COG0069	glutamate synthase activity
L2Z31_04775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z31_04865	COG1484	DNA-dependent DNA replication
L2Z31_05060	COG2026	Addiction module toxin, RelE StbE family
L2Z31_05100	COG0592	DNA-directed DNA polymerase activity
L2Z31_05220	COG2814	Major facilitator Superfamily
L2Z31_05235	COG0511	ligase activity, forming carbon-carbon bonds
L2Z31_05255	COG1116	anion transmembrane transporter activity
L2Z31_05255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z31_05260	COG0745	RESPONSE REGULATOR receiver
L2Z31_05270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z31_05270	COG2146	nitrite reductase [NAD(P)H] activity
L2Z31_05275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z31_05280	COG0243	molybdopterin cofactor binding
L2Z31_05290	COG0243	molybdopterin cofactor binding
L2Z31_05295	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z31_05310	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z31_05310	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z31_05315	COG0303	'Molybdopterin
L2Z31_05325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z31_05330	COG0697	spore germination
L2Z31_05350	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z31_05355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z31_05410	COG2204	response regulator
L2Z31_05415	COG3852	Histidine kinase
L2Z31_05435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z31_05440	COG0575	Belongs to the CDS family
L2Z31_05475	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z31_05490	COG2137	regulation of response to DNA damage stimulus
L2Z31_05500	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z31_05505	COG1011	Hydrolase
L2Z31_05530	COG1522	sequence-specific DNA binding
L2Z31_05540	COG1113	amino acid transport
L2Z31_05560	COG0659	secondary active sulfate transmembrane transporter activity
L2Z31_05565	COG2135	peptidase activity
L2Z31_05580	COG3300	MHYT domain
L2Z31_05580	COG5001	Diguanylate cyclase
L2Z31_05600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z31_05600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z31_05600	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z31_05605	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z31_05610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z31_05610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z31_05640	COG0024	Methionine aminopeptidase
L2Z31_05645	COG0583	DNA-binding transcription factor activity
L2Z31_05655	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z31_05660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z31_05665	COG0517	IMP dehydrogenase activity
L2Z31_05665	COG0516	GMP reductase activity
L2Z31_05690	COG0552	protein localization to endoplasmic reticulum
L2Z31_05700	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z31_05715	COG4890	Cyd operon protein YbgT
L2Z31_05720	COG1294	oxidase, subunit
L2Z31_05740	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z31_05750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z31_05755	COG4774	siderophore transport
L2Z31_05770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z31_05775	COG0569	domain protein
L2Z31_05780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z31_05810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z31_05815	COG0542	response to heat
L2Z31_05840	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z31_05840	COG1902	pentaerythritol trinitrate reductase activity
L2Z31_05885	COG2323	membrane
L2Z31_05890	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z31_05900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z31_05905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z31_05910	COG0183	Belongs to the thiolase family
L2Z31_05915	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z31_05920	COG0596	Alpha beta hydrolase
L2Z31_05925	COG2271	Major facilitator Superfamily
L2Z31_05930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z31_05935	COG3485	protocatechuate 3,4-dioxygenase
L2Z31_05940	COG3485	protocatechuate 3,4-dioxygenase
L2Z31_05945	COG0710	3-dehydroquinate dehydratase activity
L2Z31_05950	COG3420	alginic acid biosynthetic process
L2Z31_05955	COG3659	wide pore channel activity
L2Z31_05960	COG4993	Dehydrogenase
L2Z31_05970	COG2391	methyltransferase activity
L2Z31_05985	COG1414	Transcriptional regulator
L2Z31_05990	COG0583	DNA-binding transcription factor activity
L2Z31_05995	COG1960	acyl-CoA dehydrogenase activity
L2Z31_06020	COG2814	Major facilitator Superfamily
L2Z31_06030	COG0154	amidase activity
L2Z31_06050	COG4638	Rieske (2fe-2S)
L2Z31_06060	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_06070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z31_06080	COG3733	amine oxidase
L2Z31_06090	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_06100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z31_06105	COG0183	Belongs to the thiolase family
L2Z31_06110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z31_06115	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z31_06125	COG4829	muconolactone delta-isomerase
L2Z31_06130	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z31_06135	COG0583	DNA-binding transcription factor activity
L2Z31_06145	COG2186	Transcriptional regulator
L2Z31_06165	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_06185	COG1960	acyl-CoA dehydrogenase activity
L2Z31_06190	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_06205	COG3162	membrane
L2Z31_06220	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_06235	COG0753	catalase activity
L2Z31_06255	COG1846	Transcriptional regulator
L2Z31_06260	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z31_06260	COG1902	pentaerythritol trinitrate reductase activity
L2Z31_06270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z31_06300	COG1309	transcriptional regulator
L2Z31_06310	COG1335	isochorismatase
L2Z31_06315	COG0583	DNA-binding transcription factor activity
L2Z31_06325	COG0475	glutathione-regulated potassium exporter activity
L2Z31_06325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z31_06335	COG1473	amidohydrolase
L2Z31_06345	COG2831	hemolysin activation secretion protein
L2Z31_06390	COG2188	Transcriptional regulator
L2Z31_06405	COG0583	DNA-binding transcription factor activity
L2Z31_06435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z31_06465	COG1566	PFAM secretion protein HlyD family protein
L2Z31_06480	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_06485	COG0129	dihydroxy-acid dehydratase activity
L2Z31_06495	COG0583	DNA-binding transcription factor activity
L2Z31_06500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z31_06510	COG2084	Dehydrogenase
L2Z31_06515	COG2207	Transcriptional regulator
L2Z31_06530	COG1064	alcohol dehydrogenase
L2Z31_06540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z31_06545	COG1120	ATPase activity
L2Z31_06565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z31_06685	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z31_06735	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_06750	COG2207	Transcriptional regulator
L2Z31_06760	COG2205	protein histidine kinase activity
L2Z31_06765	COG0745	RESPONSE REGULATOR receiver
L2Z31_06775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z31_06780	COG1538	Outer membrane efflux protein
L2Z31_06790	COG2072	flavoprotein involved in K transport
L2Z31_06810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z31_06830	COG3539	Fimbrial protein
L2Z31_06860	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z31_06870	COG0753	catalase activity
L2Z31_06885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z31_06945	COG3433	isochorismatase activity
L2Z31_06945	COG1535	isochorismatase
L2Z31_06950	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_06955	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z31_06960	COG4149	molybdate abc transporter
L2Z31_06965	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z31_06975	COG4638	Rieske (2fe-2S)
L2Z31_06980	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z31_06985	COG0543	2 iron, 2 sulfur cluster binding
L2Z31_06985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z31_07010	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_07025	COG2207	Transcriptional regulator
L2Z31_07035	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_07040	COG2610	gluconate transmembrane transporter activity
L2Z31_07050	COG0583	DNA-binding transcription factor activity
L2Z31_07060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z31_07065	COG2031	fatty acid transporter
L2Z31_07070	COG0183	Belongs to the thiolase family
L2Z31_07075	COG0583	DNA-binding transcription factor activity
L2Z31_07080	COG0583	DNA-binding transcription factor activity
L2Z31_07095	COG1027	Aspartate ammonia-lyase
L2Z31_07105	COG0477	Major facilitator Superfamily
L2Z31_07125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z31_07130	COG4521	taurine ABC transporter
L2Z31_07145	COG2188	Transcriptional regulator
L2Z31_07155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z31_07160	COG1733	regulation of RNA biosynthetic process
L2Z31_07165	COG3708	Transcriptional regulator
L2Z31_07165	COG2207	Transcriptional regulator
L2Z31_07180	COG0730	response to heat
L2Z31_07195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z31_07195	COG3453	Protein conserved in bacteria
L2Z31_07205	COG3781	membrane
L2Z31_07210	COG1063	alcohol dehydrogenase
L2Z31_07220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z31_07225	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z31_07230	COG0022	dehydrogenase e1 component
L2Z31_07235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z31_07240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z31_07255	COG3706	GGDEF domain
L2Z31_07270	COG0133	tryptophan synthase activity
L2Z31_07280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z31_07315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z31_07340	COG2226	methyltransferase
L2Z31_07395	COG0842	Transport permease protein
L2Z31_07400	COG0842	Transport permease protein
L2Z31_07405	COG1131	(ABC) transporter
L2Z31_07420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z31_07425	COG4773	Receptor
L2Z31_07445	COG0730	response to heat
L2Z31_07450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z31_07470	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z31_07485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z31_07525	COG4264	IucA IucC family
L2Z31_07530	COG4264	IucA IucC family
L2Z31_07550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z31_07565	COG1960	acyl-CoA dehydrogenase activity
L2Z31_07570	COG1960	acyl-CoA dehydrogenase activity
L2Z31_07575	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z31_07580	COG2207	Transcriptional regulator
L2Z31_07585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z31_07590	COG0776	regulation of translation
L2Z31_07615	COG0822	iron-sulfur transferase activity
L2Z31_07620	COG0316	Belongs to the HesB IscA family
L2Z31_07650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z31_07670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z31_07675	COG0702	epimerase
L2Z31_07710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z31_07720	COG0339	signal peptide processing
L2Z31_07770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z31_07775	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z31_07805	COG0776	regulation of translation
L2Z31_07870	COG0084	hydrolase, TatD family'
L2Z31_07890	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z31_07895	COG1132	(ABC) transporter
L2Z31_07905	COG0811	peptide transport
L2Z31_07910	COG1475	DNA binding
L2Z31_07915	COG1192	Involved in chromosome partitioning
L2Z31_07925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z31_07940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z31_07945	COG0191	fructose-bisphosphate aldolase activity
L2Z31_07965	COG0424	maF-like protein
L2Z31_07970	COG2850	peptidyl-arginine hydroxylation
L2Z31_07980	COG0640	Transcriptional regulator
L2Z31_07990	COG3619	membrane
L2Z31_07995	COG3122	Protein conserved in bacteria
L2Z31_08000	COG1132	(ABC) transporter
L2Z31_08020	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z31_08025	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z31_08035	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z31_08035	COG0506	proline dehydrogenase activity
L2Z31_08035	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z31_08040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z31_08055	COG3698	Phosphodiester glycosidase
L2Z31_08065	COG2353	YceI-like domain
L2Z31_08075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z31_08120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z31_08120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z31_08145	COG3539	Fimbrial protein
L2Z31_08150	COG3121	Chaperone
L2Z31_08175	COG0697	spore germination
L2Z31_08185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z31_08195	COG0583	DNA-binding transcription factor activity
L2Z31_08215	COG1309	transcriptional regulator
L2Z31_08230	COG1522	sequence-specific DNA binding
L2Z31_08240	COG1126	abc transporter atp-binding protein
L2Z31_08245	COG0765	amino acid transport
L2Z31_08250	COG0765	amino acid transport
L2Z31_08280	COG1464	Belongs to the NlpA lipoprotein family
L2Z31_08290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z31_08295	COG2011	ABC-type metal ion transport system permease component
L2Z31_08300	COG0012	GTP binding
L2Z31_08325	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z31_08365	COG0386	Belongs to the glutathione peroxidase family
L2Z31_08375	COG0436	Aminotransferase
L2Z31_08415	COG3634	alkyl hydroperoxide reductase activity
L2Z31_08430	COG0583	DNA-binding transcription factor activity
L2Z31_08435	COG0798	PFAM Bile acid sodium symporter
L2Z31_08440	COG0640	Transcriptional regulator
L2Z31_08475	COG0583	DNA-binding transcription factor activity
L2Z31_08485	COG1953	Uracil, thiamine, allantoin
L2Z31_08495	COG2175	clavaminate synthase activity
L2Z31_08500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z31_08505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z31_08510	COG4521	taurine ABC transporter
L2Z31_08520	COG0477	Major facilitator Superfamily
L2Z31_08540	COG1271	oxidase subunit
L2Z31_08545	COG1294	oxidase, subunit
L2Z31_08555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z31_08575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z31_08595	COG3052	prosthetic group binding
L2Z31_08600	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z31_08610	COG2814	Major facilitator Superfamily
L2Z31_08630	COG1346	cytolysis
L2Z31_08640	COG0583	DNA-binding transcription factor activity
L2Z31_08645	COG0625	glutathione transferase activity
L2Z31_08650	COG0625	glutathione transferase activity
L2Z31_08655	COG0583	DNA-binding transcription factor activity
L2Z31_08670	COG1045	serine acetyltransferase
L2Z31_08675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z31_08680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z31_08690	COG1280	lysine exporter protein (LysE YggA)
L2Z31_08705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z31_08710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z31_08715	COG1126	abc transporter atp-binding protein
L2Z31_08720	COG0765	amino acid transport
L2Z31_08725	COG0765	amino acid transport
L2Z31_08745	COG0784	Response regulator, receiver
L2Z31_08745	COG2205	protein histidine kinase activity
L2Z31_08765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z31_08785	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_08835	COG0583	DNA-binding transcription factor activity
L2Z31_08855	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z31_08860	COG1309	transcriptional regulator
L2Z31_08865	COG1960	acyl-CoA dehydrogenase activity
L2Z31_08870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z31_08875	COG1024	Enoyl-CoA hydratase
L2Z31_08880	COG4770	biotin carboxylase activity
L2Z31_08890	COG0583	DNA-binding transcription factor activity
L2Z31_08905	COG1960	acyl-CoA dehydrogenase activity
L2Z31_08915	COG2814	Major facilitator Superfamily
L2Z31_08925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z31_08930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z31_08935	COG2814	Major facilitator Superfamily
L2Z31_08940	COG1960	acyl-CoA dehydrogenase activity
L2Z31_08945	COG1024	Enoyl-CoA hydratase
L2Z31_08950	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_08955	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z31_08960	COG0183	Belongs to the thiolase family
L2Z31_08970	COG2814	Major facilitator Superfamily
L2Z31_08980	COG1024	Enoyl-CoA hydratase
L2Z31_08995	COG1960	acyl-CoA dehydrogenase activity
L2Z31_09000	COG2814	Major facilitator Superfamily
L2Z31_09005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z31_09010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z31_09025	COG3842	ATPase activity
L2Z31_09030	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z31_09040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z31_09045	COG1414	Transcriptional regulator
L2Z31_09055	COG0583	DNA-binding transcription factor activity
L2Z31_09060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z31_09065	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_09075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z31_09085	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_09090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z31_09095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z31_09100	COG2267	carboxylic ester hydrolase activity
L2Z31_09120	COG3038	cytochrome b561
L2Z31_09125	COG0753	catalase activity
L2Z31_09160	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z31_09170	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z31_09175	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z31_09180	COG0183	Belongs to the thiolase family
L2Z31_09185	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z31_09190	COG1024	Enoyl-CoA hydratase
L2Z31_09195	COG1024	Enoyl-CoA hydratase
L2Z31_09200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z31_09205	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z31_09210	COG3396	Phenylacetate-CoA oxygenase
L2Z31_09215	COG3460	Phenylacetate-CoA oxygenase
L2Z31_09220	COG3396	Phenylacetate-CoA oxygenase
L2Z31_09225	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_09225	COG2030	dehydratase
L2Z31_09230	COG1760	l-serine dehydratase
L2Z31_09235	COG0531	amino acid
L2Z31_09240	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_09255	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z31_09265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z31_09285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z31_09295	COG0789	Transcriptional regulator
L2Z31_09310	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z31_09325	COG2807	transmembrane transport
L2Z31_09330	COG0590	tRNA wobble adenosine to inosine editing
L2Z31_09450	COG1116	anion transmembrane transporter activity
L2Z31_09455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z31_09465	COG0864	Transcriptional regulator
L2Z31_09485	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z31_09490	COG0439	Biotin carboxylase
L2Z31_09505	COG1063	alcohol dehydrogenase
L2Z31_09515	COG1309	transcriptional regulator
L2Z31_09535	COG0038	chloride channel
L2Z31_09540	COG4770	biotin carboxylase activity
L2Z31_09560	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z31_09565	COG0583	DNA-binding transcription factor activity
L2Z31_09615	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z31_09635	COG2814	Major facilitator Superfamily
L2Z31_09650	COG1560	Kdo2-lipid A biosynthetic process
L2Z31_09660	COG5006	permease, DMT superfamily
L2Z31_09665	COG1522	sequence-specific DNA binding
L2Z31_09680	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z31_09690	COG4122	O-methyltransferase activity
L2Z31_09720	COG1538	Outer membrane efflux protein
L2Z31_09725	COG1137	ATPase activity
L2Z31_09730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z31_09740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z31_09745	COG0517	IMP dehydrogenase activity
L2Z31_09745	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z31_09780	COG2814	Major facilitator Superfamily
L2Z31_09815	COG1278	Cold shock
L2Z31_09820	COG1280	lysine exporter protein (LysE YggA)
L2Z31_09850	COG1570	exodeoxyribonuclease VII activity
L2Z31_09900	COG0583	DNA-binding transcription factor activity
L2Z31_09910	COG4638	Rieske (2fe-2S)
L2Z31_09915	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z31_09920	COG0543	2 iron, 2 sulfur cluster binding
L2Z31_09920	COG0633	Ferredoxin
L2Z31_09925	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_09930	COG3135	benzoate transporter
L2Z31_09935	COG2814	Major facilitator Superfamily
L2Z31_09950	COG1643	Atp-dependent helicase
L2Z31_09955	COG0450	alkyl hydroperoxide reductase
L2Z31_09965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z31_09975	COG3634	alkyl hydroperoxide reductase activity
L2Z31_09995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z31_10000	COG0625	glutathione transferase activity
L2Z31_10010	COG2885	chlorophyll binding
L2Z31_10045	COG0542	response to heat
L2Z31_10060	COG1765	OsmC-like protein
L2Z31_10080	COG0667	Aldo Keto reductase
L2Z31_10095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z31_10105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z31_10115	COG0527	aspartate kinase activity
L2Z31_10125	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z31_10135	COG3038	cytochrome b561
L2Z31_10140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z31_10145	COG2252	PERMEase
L2Z31_10165	COG4269	membrane
L2Z31_10180	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z31_10180	COG1902	pentaerythritol trinitrate reductase activity
L2Z31_10190	COG3706	GGDEF domain
L2Z31_10190	COG2203	Gaf domain
L2Z31_10190	COG5001	Diguanylate cyclase
L2Z31_10190	COG4251	negative regulation of phosphorylation
L2Z31_10200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z31_10220	COG4172	Belongs to the ABC transporter superfamily
L2Z31_10225	COG4239	(ABC) transporter, permease
L2Z31_10230	COG4174	ABC transporter (Permease)
L2Z31_10240	COG0741	lytic transglycosylase activity
L2Z31_10240	COG1388	LysM domain
L2Z31_10240	COG0741	lytic transglycosylase activity
L2Z31_10240	COG1388	LysM domain
L2Z31_10245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z31_10285	COG0583	DNA-binding transcription factor activity
L2Z31_10290	COG1279	arginine transmembrane transporter activity
L2Z31_10310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z31_10315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z31_10320	COG0006	proline dipeptidase activity
L2Z31_10360	COG2194	sulfuric ester hydrolase activity
L2Z31_10405	COG0739	heme binding
L2Z31_10730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z31_10755	COG3384	dioxygenase
L2Z31_10765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z31_10770	COG2878	Part of a membrane complex involved in electron transport
L2Z31_10775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z31_10800	COG0768	penicillin binding
L2Z31_10805	COG0742	ribosomal rna small subunit methyltransferase
L2Z31_10820	COG0830	nickel cation binding
L2Z31_10830	COG0804	urea catabolic process
L2Z31_10870	COG1253	flavin adenine dinucleotide binding
L2Z31_10875	COG2851	Citrate transporter
L2Z31_10920	COG1794	racemase activity, acting on amino acids and derivatives
L2Z31_10930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z31_10930	COG3008	intermembrane lipid transfer
L2Z31_10935	COG2995	paraquat-inducible protein a
L2Z31_10945	COG2985	domain, Protein
L2Z31_10975	COG0477	Major facilitator Superfamily
L2Z31_11025	COG2186	Transcriptional regulator
L2Z31_11035	COG0786	glutamate:sodium symporter activity
L2Z31_11040	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z31_11065	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z31_11165	COG1610	YqeY-like protein
L2Z31_11170	COG4783	chaperone-mediated protein folding
L2Z31_11195	COG1286	toxin biosynthetic process
L2Z31_11225	COG0778	Nitroreductase
L2Z31_11235	COG0513	Belongs to the DEAD box helicase family
L2Z31_11260	COG2363	Small membrane protein
L2Z31_11290	COG1234	tRNA 3'-trailer cleavage
L2Z31_11295	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z31_11305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z31_11315	COG2819	hydrolase of the alpha beta superfamily
L2Z31_11320	COG1960	acyl-CoA dehydrogenase activity
L2Z31_11325	COG1301	dicarboxylic acid transport
L2Z31_11330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z31_11335	COG3139	Protein of unknown function (DUF1315)
L2Z31_11340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z31_11345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z31_11355	COG0494	nUDIX hydrolase
L2Z31_11365	COG0642	Histidine kinase
L2Z31_11380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z31_11390	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z31_11405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z31_11410	COG0826	peptidase U32
L2Z31_11415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z31_11425	COG4598	ABC transporter
L2Z31_11430	COG4160	amino acid transport
L2Z31_11435	COG4215	(ABC) transporter
L2Z31_11450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z31_11495	COG1131	(ABC) transporter
L2Z31_11500	COG0842	Transport permease protein
L2Z31_11515	COG0772	Belongs to the SEDS family
L2Z31_11520	COG2951	lytic endotransglycosylase activity
L2Z31_11545	COG2207	Transcriptional regulator
L2Z31_11560	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z31_11565	COG0024	Methionine aminopeptidase
L2Z31_11575	COG2223	nitrite transmembrane transporter activity
L2Z31_11585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z31_11590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z31_11595	COG1960	acyl-CoA dehydrogenase activity
L2Z31_11610	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z31_11615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z31_11620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z31_11640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z31_11645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z31_11650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z31_11685	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z31_11695	COG0174	glutamine synthetase
L2Z31_11710	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z31_11715	COG0308	aminopeptidase N
L2Z31_11745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z31_11755	COG0302	gtp cyclohydrolase
L2Z31_11780	COG3739	integral membrane protein
L2Z31_11795	COG1169	isochorismate synthase
L2Z31_11805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z31_11810	COG1132	(ABC) transporter
L2Z31_11815	COG1132	(ABC) transporter
L2Z31_11830	COG3433	isochorismatase activity
L2Z31_11830	COG1535	isochorismatase
L2Z31_11835	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z31_11840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z31_11850	COG4774	siderophore transport
L2Z31_11855	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z31_11860	COG4604	ABC transporter, ATP-binding protein
L2Z31_11865	COG4605	iron ion homeostasis
L2Z31_11870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z31_11875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z31_11890	COG2964	Protein conserved in bacteria
L2Z31_11900	COG1741	Belongs to the pirin family
L2Z31_11920	COG1309	transcriptional regulator
L2Z31_11930	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z31_11935	COG2814	Major facilitator Superfamily
L2Z31_11970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z31_11970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z31_11975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z31_11985	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_11995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z31_12000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z31_12005	COG0583	DNA-binding transcription factor activity
L2Z31_12010	COG1113	amino acid transport
L2Z31_12030	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z31_12030	COG2508	Transcriptional regulator
L2Z31_12065	COG2879	small protein
L2Z31_12070	COG1966	Carbon starvation protein
L2Z31_12115	COG1067	ATP-dependent peptidase activity
L2Z31_12120	COG0583	DNA-binding transcription factor activity
L2Z31_12145	COG1686	Belongs to the peptidase S11 family
L2Z31_12150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z31_12200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z31_12210	COG0573	inorganic phosphate transmembrane transporter activity
L2Z31_12215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z31_12220	COG1113	amino acid transport
L2Z31_12225	COG3961	Belongs to the TPP enzyme family
L2Z31_12230	COG1522	sequence-specific DNA binding
L2Z31_12240	COG0076	glutamate decarboxylase activity
L2Z31_12245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z31_12255	COG1309	transcriptional regulator
L2Z31_12270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z31_12305	COG0352	thiamine-phosphate diphosphorylase activity
L2Z31_12330	COG0612	Peptidase, M16
L2Z31_12340	COG1823	symporter activity
L2Z31_12345	COG0583	DNA-binding transcription factor activity
L2Z31_12350	COG0477	Major facilitator Superfamily
L2Z31_12375	COG1187	pseudouridine synthase activity
L2Z31_12390	COG1686	Belongs to the peptidase S11 family
L2Z31_12395	COG1252	NADH dehydrogenase
L2Z31_12405	COG0415	Belongs to the DNA photolyase family
L2Z31_12420	COG1215	transferase activity, transferring glycosyl groups
L2Z31_12450	COG2070	2-Nitropropane dioxygenase
L2Z31_12640	COG5410	chromosome segregation
L2Z31_12845	COG0556	nucleotide-excision repair
L2Z31_12865	COG0436	Aminotransferase
L2Z31_12895	COG4221	oxidoreductase activity
L2Z31_12905	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z31_12910	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z31_12920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z31_12935	COG0681	Belongs to the peptidase S26 family
L2Z31_12950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z31_12970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z31_12975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z31_12980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z31_12990	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z31_12995	COG4208	sulfate ABC transporter
L2Z31_13000	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z31_13005	COG0583	DNA-binding transcription factor activity
L2Z31_13010	COG4625	pathogenesis
L2Z31_13025	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z31_13040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z31_13050	COG1051	belongs to the nudix hydrolase family
L2Z31_13050	COG1056	cytidyltransferase-related domain
L2Z31_13055	COG1024	Enoyl-CoA hydratase
L2Z31_13065	COG2814	Major facilitator Superfamily
L2Z31_13070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z31_13070	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z31_13090	COG1473	amidohydrolase
L2Z31_13095	COG0824	Thioesterase
L2Z31_13115	COG0823	Involved in the tonB-independent uptake of proteins
L2Z31_13135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z31_13170	COG0628	permease
L2Z31_13180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z31_13185	COG0596	Alpha beta hydrolase
L2Z31_13190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z31_13190	COG0616	signal peptide processing
L2Z31_13200	COG2333	competence protein COMEC
L2Z31_13200	COG0658	competence protein
L2Z31_13205	COG1136	(ABC) transporter
L2Z31_13210	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z31_13245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z31_13265	COG0463	Glycosyl transferase, family 2
L2Z31_13295	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z31_13300	COG1280	lysine exporter protein (LysE YggA)
L2Z31_13310	COG0019	diaminopimelate decarboxylase activity
L2Z31_13320	COG1113	amino acid transport
L2Z31_13335	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z31_13345	COG3339	Conserved Protein
L2Z31_13350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z31_13355	COG0243	molybdopterin cofactor binding
L2Z31_13360	COG1929	Belongs to the glycerate kinase type-1 family
L2Z31_13375	COG0778	Nitroreductase
L2Z31_13405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z31_13420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z31_13440	COG0741	lytic transglycosylase activity
L2Z31_13460	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z31_13465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z31_13490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z31_13495	COG1597	lipid kinase activity
L2Z31_13510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z31_13515	COG0477	Major facilitator Superfamily
L2Z31_13565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z31_13570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z31_13595	COG0505	Belongs to the CarA family
L2Z31_13615	COG0589	response to stress
L2Z31_13630	COG2843	Capsule synthesis protein
L2Z31_13650	COG2321	neutral zinc metallopeptidase
L2Z31_13655	COG2354	Protein conserved in bacteria
L2Z31_13675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z31_13700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z31_13705	COG1053	succinate dehydrogenase
L2Z31_13710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z31_13715	COG2009	succinate dehydrogenase
L2Z31_13755	COG2921	Belongs to the UPF0250 family
L2Z31_13760	COG0321	lipoyl(octanoyl) transferase activity
L2Z31_13775	COG0531	amino acid
L2Z31_13785	COG1733	regulation of RNA biosynthetic process
L2Z31_13790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z31_13795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z31_13795	COG1648	precorrin-2 dehydrogenase activity
L2Z31_13810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z31_13840	COG0671	phosphoesterase, PA-phosphatase related
L2Z31_13845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z31_13855	COG1538	Outer membrane efflux protein
L2Z31_13860	COG0393	Putative heavy-metal-binding
L2Z31_13865	COG0393	Putative heavy-metal-binding
L2Z31_13875	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_13885	COG0525	valine-tRNA ligase activity
L2Z31_13905	COG0583	DNA-binding transcription factor activity
L2Z31_13910	COG0004	ammonium transporteR
L2Z31_13920	COG0642	Histidine kinase
L2Z31_13925	COG0745	RESPONSE REGULATOR receiver
L2Z31_13930	COG2194	sulfuric ester hydrolase activity
L2Z31_13950	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z31_13965	COG2315	Protein conserved in bacteria
L2Z31_13970	COG0142	geranyltranstransferase activity
L2Z31_13975	COG2828	Protein conserved in bacteria
L2Z31_13980	COG1113	amino acid transport
L2Z31_14000	COG2207	Transcriptional regulator
L2Z31_14025	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z31_14035	COG0560	Phosphoserine phosphatase
L2Z31_14045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z31_14055	COG1530	ribonuclease E activity
L2Z31_14060	COG0424	maF-like protein
L2Z31_14065	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z31_14070	COG1792	Involved in formation and maintenance of cell shape
L2Z31_14075	COG1077	Cell shape determining protein MreB Mrl
L2Z31_14080	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z31_14090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z31_14120	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z31_14125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z31_14130	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z31_14135	COG1115	amino acid carrier protein
L2Z31_14155	COG2814	Major facilitator Superfamily
L2Z31_14160	COG1289	transmembrane transporter activity
L2Z31_14170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z31_14210	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z31_14215	COG2832	Protein of unknown function (DUF454)
L2Z31_14225	COG5510	response to toxic substance
L2Z31_14245	COG0840	transmembrane signaling receptor activity
L2Z31_14285	COG3422	double-strand break repair
L2Z31_14290	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z31_14295	COG3189	MarR family transcriptional regulator
L2Z31_14305	COG0354	folic acid binding
L2Z31_14310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z31_14320	COG0679	Auxin Efflux Carrier
L2Z31_14325	COG1902	pentaerythritol trinitrate reductase activity
L2Z31_14345	COG2094	Belongs to the DNA glycosylase MPG family
L2Z31_14370	COG1217	gtp-binding protein TYPA
L2Z31_14375	COG2233	PERMEase
L2Z31_14385	COG0833	amino acid
L2Z31_14390	COG1690	Belongs to the RtcB family
L2Z31_14400	COG2885	chlorophyll binding
L2Z31_14400	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z31_14410	COG0183	Belongs to the thiolase family
L2Z31_14430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z31_14450	COG2207	Transcriptional regulator
L2Z31_14455	COG0183	Belongs to the thiolase family
L2Z31_14485	COG1272	protein, Hemolysin III
L2Z31_14490	COG0477	Major facilitator Superfamily
L2Z31_14505	COG0450	alkyl hydroperoxide reductase
L2Z31_14525	COG0285	dihydrofolate synthase activity
L2Z31_14575	COG2096	Adenosyltransferase
L2Z31_14595	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z31_14600	COG0745	RESPONSE REGULATOR receiver
L2Z31_14605	COG2205	protein histidine kinase activity
L2Z31_14615	COG1960	acyl-CoA dehydrogenase activity
L2Z31_14620	COG1960	acyl-CoA dehydrogenase activity
L2Z31_14625	COG0583	DNA-binding transcription factor activity
L2Z31_14630	COG0625	glutathione transferase activity
L2Z31_14695	COG0438	transferase activity, transferring glycosyl groups
L2Z31_14700	COG0463	Glycosyl transferase, family 2
L2Z31_14705	COG0726	polysaccharide deacetylase
L2Z31_14725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z31_14730	COG2205	protein histidine kinase activity
L2Z31_14780	COG1862	Preprotein translocase
L2Z31_14790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z31_14795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z31_14805	COG3781	membrane
L2Z31_14810	COG0613	PHP domain protein
L2Z31_14820	COG2350	Protein conserved in bacteria
L2Z31_14850	COG1607	acyl-coa hydrolase
L2Z31_14910	COG2199	diguanylate cyclase activity
L2Z31_14920	COG1408	metallophosphoesterase
L2Z31_14925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z31_14935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z31_14955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z31_14960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z31_14975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z31_14985	COG2969	positive regulation of protein catabolic process
L2Z31_15005	COG1960	acyl-CoA dehydrogenase activity
L2Z31_15010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z31_15025	COG1309	transcriptional regulator
L2Z31_15030	COG1960	acyl-CoA dehydrogenase activity
L2Z31_15075	COG1183	phosphatidylcholine synthase activity
L2Z31_15080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z31_15110	COG0739	heme binding
L2Z31_15110	COG0741	lytic transglycosylase activity
L2Z31_15110	COG1196	nuclear chromosome segregation
L2Z31_15120	COG1702	phosphate starvation-inducible protein PhoH
L2Z31_15155	COG1295	ribonuclease BN
L2Z31_15160	COG0697	spore germination
L2Z31_15165	COG2169	Transcriptional regulator
L2Z31_15170	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z31_15215	COG0557	exoribonuclease II activity
L2Z31_15220	COG0339	signal peptide processing
L2Z31_15225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z31_15255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z31_15260	COG1960	acyl-CoA dehydrogenase activity
L2Z31_15415	COG0626	cystathionine gamma-synthase activity
L2Z31_15420	COG0433	COG0433 Predicted ATPase
L2Z31_15425	COG1017	nitric oxide dioxygenase activity
L2Z31_15425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z31_15430	COG1959	2 iron, 2 sulfur cluster binding
L2Z31_15445	COG1301	dicarboxylic acid transport
L2Z31_15450	COG1946	Acyl-CoA thioesterase
L2Z31_15470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z31_15475	COG1040	competence protein
L2Z31_15480	COG0494	nUDIX hydrolase
L2Z31_15490	COG0598	Magnesium transport protein CorA
L2Z31_15500	COG2854	intermembrane phospholipid transfer
L2Z31_15510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z31_15515	COG1127	ABC transporter
L2Z31_15525	COG0513	Belongs to the DEAD box helicase family
L2Z31_15545	COG0408	coproporphyrinogen oxidase activity
L2Z31_15565	COG1960	acyl-CoA dehydrogenase activity
L2Z31_15575	COG1983	PspC domain protein
L2Z31_15580	COG0517	IMP dehydrogenase activity
L2Z31_15625	COG0583	DNA-binding transcription factor activity
L2Z31_15665	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_15675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z31_15680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z31_15685	COG0833	amino acid
L2Z31_15715	COG1192	Involved in chromosome partitioning
L2Z31_15720	COG0628	permease
L2Z31_15730	COG1289	transmembrane transporter activity
L2Z31_15745	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z31_15750	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z31_15760	COG0277	FAD linked oxidase domain protein
L2Z31_15765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z31_15790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z31_15795	COG5380	lipid catabolic process
L2Z31_15815	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z31_15865	COG0194	GDP metabolic process
L2Z31_15880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z31_15900	COG3307	-O-antigen
L2Z31_15920	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z31_15925	COG1704	LemA family
L2Z31_15935	COG0493	'glutamate synthase
L2Z31_15940	COG0067	glutamate synthase
L2Z31_15940	COG0069	glutamate synthase activity
L2Z31_15940	COG0070	glutamate synthase
L2Z31_15990	COG2226	methyltransferase
L2Z31_16005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z31_16010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z31_16055	COG0833	amino acid
L2Z31_16140	COG0488	(ABC) transporter
L2Z31_16145	COG2873	o-acetylhomoserine
L2Z31_16150	COG4221	oxidoreductase activity
L2Z31_16155	COG0659	secondary active sulfate transmembrane transporter activity
L2Z31_16180	COG0427	acetyl-CoA hydrolase
L2Z31_16210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z31_16240	COG2329	Antibiotic biosynthesis monooxygenase
L2Z31_16255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z31_16320	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z31_16325	COG1733	regulation of RNA biosynthetic process
L2Z31_16360	COG0667	Aldo Keto reductase
L2Z31_16380	COG0583	DNA-binding transcription factor activity
L2Z31_16385	COG2814	Major facilitator Superfamily
L2Z31_16415	COG1335	isochorismatase
L2Z31_16425	COG1012	belongs to the aldehyde dehydrogenase family
L2Z31_16430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z31_16440	COG1113	amino acid transport
L2Z31_16450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z31_16465	COG2814	Major facilitator Superfamily
L2Z31_16475	COG0351	phosphomethylpyrimidine kinase
L2Z31_16475	COG0352	thiamine-phosphate diphosphorylase activity
L2Z31_16475	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z31_16495	COG1309	transcriptional regulator
L2Z31_16500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z31_16515	COG1002	Type II restriction enzyme, methylase subunits
L2Z31_16520	COG1061	Type III restriction enzyme res subunit
L2Z31_16555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z31_16565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z31_16570	COG3162	membrane
L2Z31_16575	COG0784	Response regulator, receiver
L2Z31_16575	COG2198	Histidine kinase
L2Z31_16575	COG2205	protein histidine kinase activity
L2Z31_16600	COG3328	transposase activity
L2Z31_16605	COG1522	sequence-specific DNA binding
L2Z31_16610	COG1335	isochorismatase
L2Z31_16615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z31_16625	COG0668	transmembrane transport
L2Z31_16630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z31_16635	COG1519	Transferase
L2Z31_16640	COG1902	pentaerythritol trinitrate reductase activity
L2Z31_16660	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z31_16685	COG0426	domain, Protein
L2Z31_16685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z31_16705	COG2119	membrane
L2Z31_16715	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z31_16725	COG4942	peptidase
L2Z31_16740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z31_16750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z31_16770	COG0189	ligase activity
L2Z31_16790	COG0708	Exodeoxyribonuclease III
L2Z31_16795	COG1393	Belongs to the ArsC family
L2Z31_16810	COG3706	GGDEF domain
L2Z31_16845	COG2351	hydroxyisourate hydrolase activity
L2Z31_16850	COG2233	PERMEase
L2Z31_16860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z31_16870	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z31_16875	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_16885	COG3150	esterase
L2Z31_16900	COG0791	NLP P60 protein
L2Z31_16900	COG1388	LysM domain
L2Z31_16915	COG2918	glutathione biosynthetic process
L2Z31_16930	COG2733	membrane
L2Z31_16935	COG0436	Aminotransferase
L2Z31_16940	COG0534	Mate efflux family protein
L2Z31_17040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z31_17045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z31_17055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z31_17060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z31_17075	COG0010	Belongs to the arginase family
L2Z31_17105	COG2188	Transcriptional regulator
L2Z31_17115	COG0523	cobalamin synthesis protein
L2Z31_17125	COG1113	amino acid transport
L2Z31_17135	COG0625	glutathione transferase activity
L2Z31_17155	COG1683	Conserved Protein
L2Z31_17160	COG0534	Mate efflux family protein
L2Z31_17165	COG0385	Bile acid
L2Z31_17170	COG1335	isochorismatase
L2Z31_17175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z31_17195	COG2116	formate transmembrane transporter activity
L2Z31_17200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z31_17205	COG2133	pyrroloquinoline quinone binding
L2Z31_17210	COG2983	Belongs to the UPF0260 family
L2Z31_17230	COG1194	a g-specific adenine glycosylase
L2Z31_17245	COG2818	Glycosylase
L2Z31_17250	COG1064	alcohol dehydrogenase
L2Z31_17255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z31_17270	COG0583	DNA-binding transcription factor activity
L2Z31_17275	COG0656	L-ascorbic acid biosynthetic process
L2Z31_17280	COG2814	Major facilitator Superfamily
L2Z31_17315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z31_17330	COG2233	PERMEase
L2Z31_17370	COG0733	neurotransmitter:sodium symporter activity
L2Z31_17410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z31_17415	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z31_17420	COG0596	Alpha beta hydrolase
L2Z31_17445	COG0488	(ABC) transporter
L2Z31_17450	COG0586	Pfam SNARE associated Golgi protein
L2Z31_17460	COG0187	DNA topoisomerase II activity
L2Z31_17470	COG0592	DNA-directed DNA polymerase activity
L2Z31_17495	COG0706	membrane insertase activity
L2Z31_17510	COG1230	cation diffusion facilitator family transporter
L2Z31_17515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z31_17530	COG0402	S-adenosylhomocysteine deaminase activity
L2Z31_17540	COG0754	glutathionylspermidine amidase activity
L2Z31_17550	COG0861	Integral membrane protein TerC family
L2Z31_17555	COG0671	phosphoesterase, PA-phosphatase related
L2Z31_17565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z31_17580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z31_17585	COG2951	lytic endotransglycosylase activity
L2Z31_17615	COG0583	DNA-binding transcription factor activity
L2Z31_17635	COG0657	acetylesterase activity
L2Z31_17640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z31_17685	COG1047	Peptidyl-prolyl cis-trans
L2Z31_17695	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z31_17700	COG0196	riboflavin kinase activity
L2Z31_17710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z31_17715	COG1309	transcriptional regulator
L2Z31_17720	COG1116	anion transmembrane transporter activity
L2Z31_17725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z31_17730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z31_17735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z31_17740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z31_17760	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z31_17765	COG0546	phosphoglycolate phosphatase activity
L2Z31_17820	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z31_17825	COG0728	peptidoglycan biosynthetic process
L2Z31_17850	COG1596	polysaccharide export
L2Z31_17855	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z31_17910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z31_17915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z31_17920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z31_17935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z31_17940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z31_17950	COG2186	Transcriptional regulator
L2Z31_17960	COG0277	FAD linked oxidase domain protein
L2Z31_17965	COG1448	Aminotransferase
L2Z31_17975	COG1802	Transcriptional regulator
L2Z31_17990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z31_18060	COG0564	pseudouridine synthase activity
L2Z31_18100	COG0251	oxidation-reduction process
L2Z31_18105	COG1113	amino acid transport
L2Z31_18110	COG1113	amino acid transport
L2Z31_18130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z31_18135	COG1960	acyl-CoA dehydrogenase activity
L2Z31_18140	COG1024	Enoyl-CoA hydratase
L2Z31_18145	COG1024	Enoyl-CoA hydratase
L2Z31_18150	COG0477	Major facilitator Superfamily
L2Z31_18155	COG0019	diaminopimelate decarboxylase activity
L2Z31_18160	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z31_18170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z31_18175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
L2Z31_18180	COG1846	Transcriptional regulator
L2Z31_18185	COG3916	Acyl-homoserine-lactone synthase
L2Z31_18195	COG2197	response regulator
L2Z31_18205	COG1960	acyl-CoA dehydrogenase activity
L2Z31_18210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z31_18210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z31_18210	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z31_18210	COG3321	synthase
L2Z31_18250	COG0271	Belongs to the BolA IbaG family
L2Z31_18260	COG1192	Involved in chromosome partitioning
L2Z31_18275	COG0586	Pfam SNARE associated Golgi protein
L2Z31_18280	COG2259	Doxx family
L2Z31_18285	COG4399	Belongs to the UPF0754 family
L2Z31_18290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z31_18290	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z31_18335	COG0281	malic enzyme
L2Z31_18340	COG2837	iron assimilation
L2Z31_18345	COG1280	lysine exporter protein (LysE YggA)
L2Z31_18350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z31_18355	COG1121	(ABC) transporter
L2Z31_18420	COG0386	Belongs to the glutathione peroxidase family
L2Z31_18435	COG1309	transcriptional regulator
L2Z31_18440	COG0697	spore germination
L2Z31_18450	COG0758	DNA mediated transformation
L2Z31_18520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z31_18530	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z31_18570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z31_18590	COG1253	flavin adenine dinucleotide binding
L2Z31_18600	COG2860	membrane
L2Z31_18605	COG0477	Major facilitator Superfamily
L2Z31_18615	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z31_18630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z31_18650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z31_18660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z31_18705	COG0589	response to stress
L2Z31_18710	COG0659	secondary active sulfate transmembrane transporter activity
L2Z31_18740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z31_18785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate