locus-tag	class	description
L2Z33_00010	COG1074	ATP-dependent DNA helicase activity
L2Z33_00015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z33_00020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z33_00035	COG0598	Magnesium transport protein CorA
L2Z33_00040	COG0789	Transcriptional regulator
L2Z33_00045	COG0484	heat shock protein binding
L2Z33_00055	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z33_00060	COG0475	glutathione-regulated potassium exporter activity
L2Z33_00060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z33_00065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z33_00085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z33_00095	COG4535	Mg2 and Co2 transporter CorC
L2Z33_00100	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z33_00105	COG0644	oxidoreductase
L2Z33_00105	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z33_00115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z33_00130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z33_00135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z33_00175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z33_00190	COG0534	Mate efflux family protein
L2Z33_00200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z33_00205	COG4221	oxidoreductase activity
L2Z33_00210	COG0583	DNA-binding transcription factor activity
L2Z33_00225	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z33_00230	COG1530	ribonuclease E activity
L2Z33_00240	COG0546	phosphoglycolate phosphatase activity
L2Z33_00245	COG2378	regulation of single-species biofilm formation
L2Z33_00250	COG0625	glutathione transferase activity
L2Z33_00260	COG0583	DNA-binding transcription factor activity
L2Z33_00325	COG0473	3-isopropylmalate dehydrogenase activity
L2Z33_00380	COG1301	dicarboxylic acid transport
L2Z33_00390	COG1560	Kdo2-lipid A biosynthetic process
L2Z33_00395	COG1280	lysine exporter protein (LysE YggA)
L2Z33_00400	COG0488	(ABC) transporter
L2Z33_00405	COG2900	Belongs to the SlyX family
L2Z33_00415	COG1733	regulation of RNA biosynthetic process
L2Z33_00440	COG0210	DNA helicase
L2Z33_00445	COG0724	RNA recognition motif
L2Z33_00465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z33_00465	COG4651	solute:proton antiporter activity
L2Z33_00490	COG0788	formyltetrahydrofolate deformylase activity
L2Z33_00590	COG2813	Specifically methylates the guanine in position
L2Z33_00590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z33_00600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z33_00610	COG4774	siderophore transport
L2Z33_00620	COG0740	serine-type endopeptidase activity
L2Z33_00640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z33_00640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z33_00645	COG0280	phosphate acetyltransferase
L2Z33_00645	COG0857	belongs to the CobB CobQ family
L2Z33_00650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z33_00660	COG0800	Aldolase
L2Z33_00670	COG3265	gluconokinase activity
L2Z33_00675	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_00685	COG2267	carboxylic ester hydrolase activity
L2Z33_00700	COG0793	Belongs to the peptidase S41A family
L2Z33_00735	COG1426	Protein conserved in bacteria
L2Z33_00780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z33_00790	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z33_00805	COG2986	histidine ammonia-lyase
L2Z33_00845	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_00850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z33_00870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z33_00880	COG1162	GTPase activity
L2Z33_00885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z33_00900	COG1538	Outer membrane efflux protein
L2Z33_00905	COG0577	efflux transmembrane transporter activity
L2Z33_00905	COG1136	(ABC) transporter
L2Z33_00910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z33_00935	COG0028	Belongs to the TPP enzyme family
L2Z33_00940	COG0440	acetolactate synthase activity
L2Z33_00970	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z33_00985	COG0084	hydrolase, TatD family'
L2Z33_01000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z33_01010	COG0583	DNA-binding transcription factor activity
L2Z33_01020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z33_01025	COG2814	Major facilitator Superfamily
L2Z33_01075	COG3622	Belongs to the hyi family
L2Z33_01080	COG2084	Dehydrogenase
L2Z33_01085	COG1024	Enoyl-CoA hydratase
L2Z33_01090	COG5002	protein histidine kinase activity
L2Z33_01090	COG2205	protein histidine kinase activity
L2Z33_01090	COG0784	Response regulator, receiver
L2Z33_01110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z33_01120	COG3956	TIGRFAM MazG family protein
L2Z33_01125	COG1555	photosystem II stabilization
L2Z33_01130	COG0617	tRNA 3'-terminal CCA addition
L2Z33_01135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z33_01155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z33_01160	COG3028	Belongs to the UPF0307 family
L2Z33_01165	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z33_01180	COG0625	glutathione transferase activity
L2Z33_01185	COG1238	metal cluster binding
L2Z33_01230	COG0072	phenylalanine-tRNA ligase activity
L2Z33_01260	COG0248	Ppx GppA phosphatase
L2Z33_01270	COG0037	tRNA processing
L2Z33_01310	COG1764	response to oxidative stress
L2Z33_01315	COG1846	Transcriptional regulator
L2Z33_01325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z33_01385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z33_01390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z33_01395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z33_01405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z33_01470	COG1214	PFAM Peptidase M22, glycoprotease
L2Z33_01495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z33_01500	COG0561	phosphatase activity
L2Z33_01510	COG2132	Multicopper oxidase
L2Z33_01515	COG3667	copper resistance
L2Z33_01530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z33_01535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z33_01540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z33_01570	COG1063	alcohol dehydrogenase
L2Z33_01575	COG0583	DNA-binding transcription factor activity
L2Z33_01580	COG1960	acyl-CoA dehydrogenase activity
L2Z33_01585	COG2814	Major facilitator Superfamily
L2Z33_01590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z33_01600	COG1053	succinate dehydrogenase
L2Z33_01605	COG0583	DNA-binding transcription factor activity
L2Z33_01620	COG0583	DNA-binding transcription factor activity
L2Z33_01650	COG0583	DNA-binding transcription factor activity
L2Z33_01665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z33_01690	COG0384	phenazine biosynthesis protein PhzF
L2Z33_01710	COG4993	Dehydrogenase
L2Z33_01785	COG2205	protein histidine kinase activity
L2Z33_01795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z33_01815	COG0745	RESPONSE REGULATOR receiver
L2Z33_01855	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z33_01885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z33_01890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z33_01910	COG0583	DNA-binding transcription factor activity
L2Z33_01930	COG0668	transmembrane transport
L2Z33_01940	COG2081	HI0933 family
L2Z33_01945	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z33_01975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z33_01975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z33_01985	COG0489	protein tyrosine kinase activity
L2Z33_02035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z33_02045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z33_02060	COG0730	response to heat
L2Z33_02070	COG1196	nuclear chromosome segregation
L2Z33_02090	COG2223	nitrite transmembrane transporter activity
L2Z33_02095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z33_02100	COG1877	trehalose-phosphatase activity
L2Z33_02105	COG2226	methyltransferase
L2Z33_02105	COG0596	Alpha beta hydrolase
L2Z33_02105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z33_02120	COG4106	trans-aconitate 2-methyltransferase activity
L2Z33_02135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z33_02140	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z33_02145	COG0009	L-threonylcarbamoyladenylate synthase
L2Z33_02150	COG3101	peptidyl-lysine hydroxylation
L2Z33_02155	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z33_02180	COG1652	LysM domain
L2Z33_02185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z33_02185	COG0351	phosphomethylpyrimidine kinase
L2Z33_02185	COG0352	thiamine-phosphate diphosphorylase activity
L2Z33_02195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z33_02225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z33_02255	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z33_02270	COG0358	DNA primase activity
L2Z33_02280	COG0564	pseudouridine synthase activity
L2Z33_02290	COG2826	transposase and inactivated derivatives, IS30 family
L2Z33_02310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z33_02330	COG0583	DNA-binding transcription factor activity
L2Z33_02335	COG0473	3-isopropylmalate dehydrogenase activity
L2Z33_02345	COG0657	acetylesterase activity
L2Z33_02355	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_02375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z33_02375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z33_02390	COG1981	membrane
L2Z33_02435	COG0456	acetyltransferase
L2Z33_02445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z33_02450	COG0492	ferredoxin-NADP+ reductase activity
L2Z33_02455	COG1674	ftsk spoiiie
L2Z33_02455	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z33_02465	COG4372	Transposase
L2Z33_02505	COG2894	cell division
L2Z33_02520	COG0204	Acyl-transferase
L2Z33_02525	COG2885	chlorophyll binding
L2Z33_02530	COG0210	DNA helicase
L2Z33_02540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z33_02555	COG0121	glutamine amidotransferase
L2Z33_02575	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z33_02580	COG0735	belongs to the Fur family
L2Z33_02605	COG0420	3'-5' exonuclease activity
L2Z33_02625	COG1090	epimerase
L2Z33_02640	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z33_02650	COG2814	Major facilitator Superfamily
L2Z33_02655	COG0405	Gamma-glutamyltransferase
L2Z33_02695	COG0477	Major facilitator Superfamily
L2Z33_02700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z33_02710	COG1595	DNA-templated transcription, initiation
L2Z33_02770	COG0531	amino acid
L2Z33_02775	COG2040	homocysteine
L2Z33_02800	COG1309	transcriptional regulator
L2Z33_02805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z33_02810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z33_02820	COG1607	acyl-coa hydrolase
L2Z33_02830	COG0523	cobalamin synthesis protein
L2Z33_02840	COG4681	YaeQ
L2Z33_02850	COG0726	polysaccharide deacetylase
L2Z33_02850	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z33_02855	COG1215	transferase activity, transferring glycosyl groups
L2Z33_02865	COG1024	Enoyl-CoA hydratase
L2Z33_02880	COG1414	Transcriptional regulator
L2Z33_02900	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_02910	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z33_02915	COG2271	Major facilitator Superfamily
L2Z33_02925	COG2267	carboxylic ester hydrolase activity
L2Z33_02930	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_02945	COG0028	Belongs to the TPP enzyme family
L2Z33_02955	COG0477	Major facilitator Superfamily
L2Z33_02960	COG0242	peptide deformylase activity
L2Z33_02965	COG2066	Belongs to the glutaminase family
L2Z33_02970	COG2207	Transcriptional regulator
L2Z33_02975	COG2223	nitrite transmembrane transporter activity
L2Z33_02990	COG0583	DNA-binding transcription factor activity
L2Z33_02995	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_03000	COG2271	Major facilitator Superfamily
L2Z33_03005	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z33_03010	COG3958	Transketolase
L2Z33_03020	COG0306	phosphate transporter
L2Z33_03040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z33_03085	COG4181	ATPase activity
L2Z33_03090	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z33_03120	COG0583	DNA-binding transcription factor activity
L2Z33_03130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z33_03135	COG1773	rubredoxin
L2Z33_03185	COG2851	Citrate transporter
L2Z33_03190	COG1253	flavin adenine dinucleotide binding
L2Z33_03230	COG0804	urea catabolic process
L2Z33_03240	COG0830	nickel cation binding
L2Z33_03255	COG0742	ribosomal rna small subunit methyltransferase
L2Z33_03260	COG0768	penicillin binding
L2Z33_03285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z33_03290	COG2878	Part of a membrane complex involved in electron transport
L2Z33_03295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z33_03305	COG3384	dioxygenase
L2Z33_03330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z33_03515	COG5410	chromosome segregation
L2Z33_03630	COG0739	heme binding
L2Z33_03675	COG2194	sulfuric ester hydrolase activity
L2Z33_03715	COG0006	proline dipeptidase activity
L2Z33_03720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z33_03725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z33_03745	COG1279	arginine transmembrane transporter activity
L2Z33_03750	COG0583	DNA-binding transcription factor activity
L2Z33_03790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z33_03795	COG0741	lytic transglycosylase activity
L2Z33_03795	COG1388	LysM domain
L2Z33_03795	COG1388	LysM domain
L2Z33_03795	COG0741	lytic transglycosylase activity
L2Z33_03805	COG4174	ABC transporter (Permease)
L2Z33_03810	COG4239	(ABC) transporter, permease
L2Z33_03815	COG4172	Belongs to the ABC transporter superfamily
L2Z33_03835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z33_03845	COG3706	GGDEF domain
L2Z33_03845	COG4251	negative regulation of phosphorylation
L2Z33_03845	COG5001	Diguanylate cyclase
L2Z33_03845	COG2203	Gaf domain
L2Z33_03855	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z33_03855	COG1902	pentaerythritol trinitrate reductase activity
L2Z33_03870	COG4269	membrane
L2Z33_03915	COG1309	transcriptional regulator
L2Z33_03920	COG1741	Belongs to the pirin family
L2Z33_03935	COG2072	flavoprotein involved in K transport
L2Z33_03945	COG2252	PERMEase
L2Z33_03950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z33_03955	COG3038	cytochrome b561
L2Z33_03965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z33_03975	COG0527	aspartate kinase activity
L2Z33_03985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z33_03995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z33_04010	COG0667	Aldo Keto reductase
L2Z33_04025	COG1765	OsmC-like protein
L2Z33_04040	COG0542	response to heat
L2Z33_04075	COG2885	chlorophyll binding
L2Z33_04085	COG0625	glutathione transferase activity
L2Z33_04090	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z33_04120	COG3634	alkyl hydroperoxide reductase activity
L2Z33_04130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z33_04140	COG0450	alkyl hydroperoxide reductase
L2Z33_04145	COG1643	Atp-dependent helicase
L2Z33_04160	COG2814	Major facilitator Superfamily
L2Z33_04165	COG3135	benzoate transporter
L2Z33_04170	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_04175	COG0543	2 iron, 2 sulfur cluster binding
L2Z33_04175	COG0633	Ferredoxin
L2Z33_04180	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z33_04185	COG4638	Rieske (2fe-2S)
L2Z33_04195	COG0583	DNA-binding transcription factor activity
L2Z33_04250	COG1570	exodeoxyribonuclease VII activity
L2Z33_04280	COG1280	lysine exporter protein (LysE YggA)
L2Z33_04285	COG1278	Cold shock
L2Z33_04325	COG2814	Major facilitator Superfamily
L2Z33_04340	COG2826	transposase and inactivated derivatives, IS30 family
L2Z33_04375	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z33_04375	COG0517	IMP dehydrogenase activity
L2Z33_04380	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z33_04390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z33_04395	COG1137	ATPase activity
L2Z33_04400	COG1538	Outer membrane efflux protein
L2Z33_04430	COG4122	O-methyltransferase activity
L2Z33_04440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z33_04455	COG1522	sequence-specific DNA binding
L2Z33_04460	COG5006	permease, DMT superfamily
L2Z33_04470	COG1560	Kdo2-lipid A biosynthetic process
L2Z33_04485	COG2814	Major facilitator Superfamily
L2Z33_04505	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z33_04570	COG0583	DNA-binding transcription factor activity
L2Z33_04575	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z33_04595	COG4770	biotin carboxylase activity
L2Z33_04600	COG0038	chloride channel
L2Z33_04620	COG1309	transcriptional regulator
L2Z33_04655	COG0439	Biotin carboxylase
L2Z33_04660	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z33_04680	COG0864	Transcriptional regulator
L2Z33_04690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z33_04695	COG1116	anion transmembrane transporter activity
L2Z33_04820	COG0590	tRNA wobble adenosine to inosine editing
L2Z33_04825	COG2807	transmembrane transport
L2Z33_04840	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z33_04850	COG0789	Transcriptional regulator
L2Z33_04860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z33_04880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z33_04890	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z33_04905	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_04910	COG0531	amino acid
L2Z33_04915	COG1760	l-serine dehydratase
L2Z33_04920	COG2030	dehydratase
L2Z33_04920	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_04930	COG3396	Phenylacetate-CoA oxygenase
L2Z33_04935	COG3460	Phenylacetate-CoA oxygenase
L2Z33_04940	COG3396	Phenylacetate-CoA oxygenase
L2Z33_04945	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z33_04950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z33_04955	COG1024	Enoyl-CoA hydratase
L2Z33_04960	COG1024	Enoyl-CoA hydratase
L2Z33_04965	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z33_04970	COG0183	Belongs to the thiolase family
L2Z33_04975	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z33_04980	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z33_04990	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z33_05000	COG0556	nucleotide-excision repair
L2Z33_05035	COG1278	Cold shock
L2Z33_05045	COG2207	Transcriptional regulator
L2Z33_05115	COG1414	Transcriptional regulator
L2Z33_05120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z33_05135	COG3842	ATPase activity
L2Z33_05150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z33_05155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z33_05160	COG2814	Major facilitator Superfamily
L2Z33_05165	COG1960	acyl-CoA dehydrogenase activity
L2Z33_05180	COG1024	Enoyl-CoA hydratase
L2Z33_05190	COG2814	Major facilitator Superfamily
L2Z33_05200	COG0183	Belongs to the thiolase family
L2Z33_05205	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z33_05210	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_05215	COG1024	Enoyl-CoA hydratase
L2Z33_05220	COG1960	acyl-CoA dehydrogenase activity
L2Z33_05225	COG2814	Major facilitator Superfamily
L2Z33_05230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z33_05235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z33_05245	COG2814	Major facilitator Superfamily
L2Z33_05255	COG1960	acyl-CoA dehydrogenase activity
L2Z33_05270	COG0583	DNA-binding transcription factor activity
L2Z33_05280	COG4770	biotin carboxylase activity
L2Z33_05285	COG1024	Enoyl-CoA hydratase
L2Z33_05290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z33_05295	COG1960	acyl-CoA dehydrogenase activity
L2Z33_05300	COG1309	transcriptional regulator
L2Z33_05305	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z33_05325	COG0583	DNA-binding transcription factor activity
L2Z33_05375	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_05395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z33_05415	COG2205	protein histidine kinase activity
L2Z33_05415	COG0784	Response regulator, receiver
L2Z33_05435	COG0765	amino acid transport
L2Z33_05440	COG0765	amino acid transport
L2Z33_05445	COG1126	abc transporter atp-binding protein
L2Z33_05450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z33_05455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z33_05470	COG1280	lysine exporter protein (LysE YggA)
L2Z33_05480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z33_05485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z33_05490	COG1045	serine acetyltransferase
L2Z33_05505	COG0583	DNA-binding transcription factor activity
L2Z33_05510	COG0625	glutathione transferase activity
L2Z33_05515	COG0625	glutathione transferase activity
L2Z33_05520	COG0583	DNA-binding transcription factor activity
L2Z33_05530	COG1346	cytolysis
L2Z33_05550	COG2814	Major facilitator Superfamily
L2Z33_05560	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z33_05565	COG3052	prosthetic group binding
L2Z33_05585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z33_05605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z33_05615	COG1294	oxidase, subunit
L2Z33_05620	COG1271	oxidase subunit
L2Z33_05640	COG0477	Major facilitator Superfamily
L2Z33_05660	COG4521	taurine ABC transporter
L2Z33_05665	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z33_05670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z33_05675	COG2175	clavaminate synthase activity
L2Z33_05685	COG1953	Uracil, thiamine, allantoin
L2Z33_05695	COG0583	DNA-binding transcription factor activity
L2Z33_05705	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z33_05720	COG0640	Transcriptional regulator
L2Z33_05725	COG0798	PFAM Bile acid sodium symporter
L2Z33_05730	COG0583	DNA-binding transcription factor activity
L2Z33_05745	COG3634	alkyl hydroperoxide reductase activity
L2Z33_05780	COG0436	Aminotransferase
L2Z33_05790	COG0386	Belongs to the glutathione peroxidase family
L2Z33_05830	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z33_05855	COG0012	GTP binding
L2Z33_05860	COG2011	ABC-type metal ion transport system permease component
L2Z33_05865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z33_05875	COG1464	Belongs to the NlpA lipoprotein family
L2Z33_05905	COG0765	amino acid transport
L2Z33_05910	COG0765	amino acid transport
L2Z33_05915	COG1126	abc transporter atp-binding protein
L2Z33_05925	COG1522	sequence-specific DNA binding
L2Z33_05945	COG1309	transcriptional regulator
L2Z33_05975	COG0583	DNA-binding transcription factor activity
L2Z33_05985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z33_05995	COG0697	spore germination
L2Z33_06025	COG3121	Chaperone
L2Z33_06030	COG3539	Fimbrial protein
L2Z33_06055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z33_06055	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z33_06105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z33_06115	COG2353	YceI-like domain
L2Z33_06125	COG3698	Phosphodiester glycosidase
L2Z33_06140	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z33_06145	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z33_06145	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z33_06145	COG0506	proline dehydrogenase activity
L2Z33_06155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z33_06160	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z33_06180	COG1132	(ABC) transporter
L2Z33_06185	COG3122	Protein conserved in bacteria
L2Z33_06190	COG3619	membrane
L2Z33_06200	COG0640	Transcriptional regulator
L2Z33_06210	COG2850	peptidyl-arginine hydroxylation
L2Z33_06215	COG0424	maF-like protein
L2Z33_06235	COG0191	fructose-bisphosphate aldolase activity
L2Z33_06240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z33_06255	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z33_06265	COG1192	Involved in chromosome partitioning
L2Z33_06270	COG1475	DNA binding
L2Z33_06275	COG0811	peptide transport
L2Z33_06285	COG1132	(ABC) transporter
L2Z33_06290	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z33_06310	COG0084	hydrolase, TatD family'
L2Z33_06375	COG0776	regulation of translation
L2Z33_06405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z33_06470	COG0305	Participates in initiation and elongation during chromosome replication
L2Z33_06555	COG4695	Portal protein
L2Z33_06615	COG0739	heme binding
L2Z33_06615	COG0741	lytic transglycosylase activity
L2Z33_06615	COG1196	nuclear chromosome segregation
L2Z33_06675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z33_06725	COG0339	signal peptide processing
L2Z33_06735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z33_06780	COG0702	epimerase
L2Z33_06785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z33_06805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z33_06835	COG0316	Belongs to the HesB IscA family
L2Z33_06840	COG0822	iron-sulfur transferase activity
L2Z33_06865	COG0776	regulation of translation
L2Z33_06870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z33_06875	COG2207	Transcriptional regulator
L2Z33_06880	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z33_06885	COG1960	acyl-CoA dehydrogenase activity
L2Z33_06890	COG1960	acyl-CoA dehydrogenase activity
L2Z33_06905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z33_06925	COG4264	IucA IucC family
L2Z33_06930	COG4264	IucA IucC family
L2Z33_06970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z33_06985	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z33_07005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z33_07010	COG0730	response to heat
L2Z33_07030	COG4773	Receptor
L2Z33_07035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z33_07070	COG1131	(ABC) transporter
L2Z33_07075	COG0842	Transport permease protein
L2Z33_07080	COG0842	Transport permease protein
L2Z33_07135	COG2226	methyltransferase
L2Z33_07160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z33_07195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z33_07205	COG0133	tryptophan synthase activity
L2Z33_07235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z33_07240	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z33_07245	COG0022	dehydrogenase e1 component
L2Z33_07250	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z33_07255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z33_07265	COG1063	alcohol dehydrogenase
L2Z33_07270	COG3781	membrane
L2Z33_07280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z33_07280	COG3453	Protein conserved in bacteria
L2Z33_07295	COG0730	response to heat
L2Z33_07310	COG3708	Transcriptional regulator
L2Z33_07310	COG2207	Transcriptional regulator
L2Z33_07315	COG1733	regulation of RNA biosynthetic process
L2Z33_07320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z33_07330	COG2188	Transcriptional regulator
L2Z33_07345	COG4521	taurine ABC transporter
L2Z33_07350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z33_07370	COG0477	Major facilitator Superfamily
L2Z33_07380	COG1027	Aspartate ammonia-lyase
L2Z33_07395	COG0583	DNA-binding transcription factor activity
L2Z33_07400	COG0583	DNA-binding transcription factor activity
L2Z33_07405	COG0183	Belongs to the thiolase family
L2Z33_07410	COG2031	fatty acid transporter
L2Z33_07415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z33_07425	COG0583	DNA-binding transcription factor activity
L2Z33_07435	COG2610	gluconate transmembrane transporter activity
L2Z33_07440	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_07445	COG2207	Transcriptional regulator
L2Z33_07460	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_07485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z33_07485	COG0543	2 iron, 2 sulfur cluster binding
L2Z33_07490	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z33_07495	COG4638	Rieske (2fe-2S)
L2Z33_07505	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z33_07510	COG4149	molybdate abc transporter
L2Z33_07515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z33_07520	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_07525	COG3433	isochorismatase activity
L2Z33_07525	COG1535	isochorismatase
L2Z33_07600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z33_07615	COG0753	catalase activity
L2Z33_07625	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z33_07655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z33_07675	COG2072	flavoprotein involved in K transport
L2Z33_07685	COG1538	Outer membrane efflux protein
L2Z33_07690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z33_07695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z33_07700	COG0745	RESPONSE REGULATOR receiver
L2Z33_07705	COG2205	protein histidine kinase activity
L2Z33_07715	COG2207	Transcriptional regulator
L2Z33_07730	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_07790	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z33_07920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z33_07940	COG1120	ATPase activity
L2Z33_07945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z33_07955	COG1064	alcohol dehydrogenase
L2Z33_07970	COG2207	Transcriptional regulator
L2Z33_07975	COG2084	Dehydrogenase
L2Z33_07985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z33_07990	COG0583	DNA-binding transcription factor activity
L2Z33_08000	COG0129	dihydroxy-acid dehydratase activity
L2Z33_08005	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_08020	COG1566	PFAM secretion protein HlyD family protein
L2Z33_08050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z33_08080	COG0583	DNA-binding transcription factor activity
L2Z33_08095	COG2188	Transcriptional regulator
L2Z33_08140	COG2831	hemolysin activation secretion protein
L2Z33_08150	COG1473	amidohydrolase
L2Z33_08160	COG0475	glutathione-regulated potassium exporter activity
L2Z33_08160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z33_08175	COG1309	transcriptional regulator
L2Z33_08205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z33_08215	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z33_08215	COG1902	pentaerythritol trinitrate reductase activity
L2Z33_08220	COG1846	Transcriptional regulator
L2Z33_08240	COG0753	catalase activity
L2Z33_08255	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_08270	COG3162	membrane
L2Z33_08280	COG3829	transcription factor binding
L2Z33_08285	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_08290	COG1960	acyl-CoA dehydrogenase activity
L2Z33_08310	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_08330	COG2186	Transcriptional regulator
L2Z33_08340	COG0583	DNA-binding transcription factor activity
L2Z33_08345	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z33_08350	COG4829	muconolactone delta-isomerase
L2Z33_08360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z33_08365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z33_08370	COG0183	Belongs to the thiolase family
L2Z33_08375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z33_08385	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_08395	COG3733	amine oxidase
L2Z33_08405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z33_08415	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_08425	COG4638	Rieske (2fe-2S)
L2Z33_08445	COG0154	amidase activity
L2Z33_08455	COG2814	Major facilitator Superfamily
L2Z33_08480	COG1960	acyl-CoA dehydrogenase activity
L2Z33_08485	COG0583	DNA-binding transcription factor activity
L2Z33_08490	COG1414	Transcriptional regulator
L2Z33_08505	COG2391	methyltransferase activity
L2Z33_08515	COG4993	Dehydrogenase
L2Z33_08520	COG3659	wide pore channel activity
L2Z33_08525	COG3420	alginic acid biosynthetic process
L2Z33_08530	COG0710	3-dehydroquinate dehydratase activity
L2Z33_08535	COG3485	protocatechuate 3,4-dioxygenase
L2Z33_08540	COG3485	protocatechuate 3,4-dioxygenase
L2Z33_08545	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z33_08550	COG2271	Major facilitator Superfamily
L2Z33_08555	COG0596	Alpha beta hydrolase
L2Z33_08560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z33_08565	COG0183	Belongs to the thiolase family
L2Z33_08570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z33_08575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z33_08585	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z33_08590	COG2323	membrane
L2Z33_08635	COG1902	pentaerythritol trinitrate reductase activity
L2Z33_08635	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z33_08660	COG0542	response to heat
L2Z33_08665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z33_08695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z33_08700	COG0569	domain protein
L2Z33_08705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z33_08720	COG4774	siderophore transport
L2Z33_08725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z33_08735	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z33_08740	COG2826	transposase and inactivated derivatives, IS30 family
L2Z33_08760	COG1294	oxidase, subunit
L2Z33_08765	COG4890	Cyd operon protein YbgT
L2Z33_08780	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z33_08790	COG0552	protein localization to endoplasmic reticulum
L2Z33_08815	COG0516	GMP reductase activity
L2Z33_08815	COG0517	IMP dehydrogenase activity
L2Z33_08820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z33_08825	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z33_08835	COG0583	DNA-binding transcription factor activity
L2Z33_08840	COG0024	Methionine aminopeptidase
L2Z33_08870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z33_08870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z33_08875	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z33_08880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z33_08880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z33_08880	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z33_08900	COG3300	MHYT domain
L2Z33_08900	COG5001	Diguanylate cyclase
L2Z33_08915	COG2135	peptidase activity
L2Z33_08920	COG0659	secondary active sulfate transmembrane transporter activity
L2Z33_08940	COG1113	amino acid transport
L2Z33_08950	COG1522	sequence-specific DNA binding
L2Z33_08975	COG1011	Hydrolase
L2Z33_08980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z33_08990	COG2137	regulation of response to DNA damage stimulus
L2Z33_09005	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z33_09040	COG0575	Belongs to the CDS family
L2Z33_09045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z33_09065	COG3852	Histidine kinase
L2Z33_09070	COG2204	response regulator
L2Z33_09125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z33_09130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z33_09150	COG0697	spore germination
L2Z33_09155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z33_09165	COG0303	'Molybdopterin
L2Z33_09170	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z33_09170	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z33_09185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z33_09190	COG0243	molybdopterin cofactor binding
L2Z33_09200	COG0243	molybdopterin cofactor binding
L2Z33_09205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z33_09210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z33_09210	COG2146	nitrite reductase [NAD(P)H] activity
L2Z33_09220	COG0745	RESPONSE REGULATOR receiver
L2Z33_09225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z33_09225	COG1116	anion transmembrane transporter activity
L2Z33_09245	COG0511	ligase activity, forming carbon-carbon bonds
L2Z33_09260	COG2814	Major facilitator Superfamily
L2Z33_09265	COG2194	sulfuric ester hydrolase activity
L2Z33_09280	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z33_09355	COG4372	Transposase
L2Z33_09395	COG5410	chromosome segregation
L2Z33_09555	COG0069	glutamate synthase activity
L2Z33_09575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z33_09585	COG1454	alcohol dehydrogenase
L2Z33_09590	COG0824	Thioesterase
L2Z33_09600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z33_09615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z33_09620	COG2030	dehydratase
L2Z33_09630	COG0183	Belongs to the thiolase family
L2Z33_09640	COG0583	DNA-binding transcription factor activity
L2Z33_09645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z33_09655	COG1522	sequence-specific DNA binding
L2Z33_09660	COG3135	benzoate transporter
L2Z33_09670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z33_09695	COG0589	response to stress
L2Z33_09700	COG0488	(ABC) transporter
L2Z33_09720	COG4773	Receptor
L2Z33_09755	COG0668	transmembrane transport
L2Z33_09765	COG1309	transcriptional regulator
L2Z33_09785	COG1605	Chorismate mutase
L2Z33_09795	COG4221	oxidoreductase activity
L2Z33_09805	COG0308	aminopeptidase N
L2Z33_09825	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z33_09835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z33_09840	COG1454	alcohol dehydrogenase
L2Z33_09860	COG0531	amino acid
L2Z33_09865	COG4303	Ethanolamine ammonia lyase large subunit
L2Z33_09870	COG4302	ethanolamine ammonia-lyase activity
L2Z33_09890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z33_09900	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z33_09915	COG0697	spore germination
L2Z33_09920	COG1923	regulation of RNA biosynthetic process
L2Z33_09930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z33_09935	COG0802	atpase or kinase
L2Z33_09955	COG1187	pseudouridine synthase activity
L2Z33_09970	COG0583	DNA-binding transcription factor activity
L2Z33_09985	COG2814	Major facilitator Superfamily
L2Z33_09990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z33_10015	COG0729	surface antigen
L2Z33_10035	COG0174	glutamine synthetase
L2Z33_10040	COG0745	RESPONSE REGULATOR receiver
L2Z33_10045	COG2205	protein histidine kinase activity
L2Z33_10055	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z33_10060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z33_10085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z33_10090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z33_10095	COG1960	acyl-CoA dehydrogenase activity
L2Z33_10110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z33_10115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z33_10135	COG0583	DNA-binding transcription factor activity
L2Z33_10150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z33_10160	COG3658	cytochrome
L2Z33_10165	COG1215	transferase activity, transferring glycosyl groups
L2Z33_10170	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z33_10170	COG0726	polysaccharide deacetylase
L2Z33_10195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z33_10200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z33_10210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z33_10235	COG0305	Participates in initiation and elongation during chromosome replication
L2Z33_10240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z33_10250	COG1305	Transglutaminase-like
L2Z33_10260	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z33_10290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z33_10295	COG0138	bifunctional purine biosynthesis protein purh
L2Z33_10300	COG0151	Belongs to the GarS family
L2Z33_10305	COG1464	Belongs to the NlpA lipoprotein family
L2Z33_10310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z33_10315	COG2011	ABC-type metal ion transport system permease component
L2Z33_10320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z33_10330	COG1301	dicarboxylic acid transport
L2Z33_10360	COG1794	racemase activity, acting on amino acids and derivatives
L2Z33_10370	COG3008	intermembrane lipid transfer
L2Z33_10370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z33_10375	COG2995	paraquat-inducible protein a
L2Z33_10385	COG2985	domain, Protein
L2Z33_10415	COG0477	Major facilitator Superfamily
L2Z33_10450	COG2186	Transcriptional regulator
L2Z33_10460	COG0786	glutamate:sodium symporter activity
L2Z33_10465	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z33_10490	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z33_10590	COG1610	YqeY-like protein
L2Z33_10595	COG4783	chaperone-mediated protein folding
L2Z33_10620	COG1286	toxin biosynthetic process
L2Z33_10650	COG0778	Nitroreductase
L2Z33_10660	COG0513	Belongs to the DEAD box helicase family
L2Z33_10685	COG2363	Small membrane protein
L2Z33_10715	COG1234	tRNA 3'-trailer cleavage
L2Z33_10720	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z33_10730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z33_10740	COG2819	hydrolase of the alpha beta superfamily
L2Z33_10745	COG1960	acyl-CoA dehydrogenase activity
L2Z33_10755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z33_10760	COG3139	Protein of unknown function (DUF1315)
L2Z33_10765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z33_10770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z33_10780	COG0494	nUDIX hydrolase
L2Z33_10790	COG0642	Histidine kinase
L2Z33_10805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z33_10815	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z33_10830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z33_10835	COG0826	peptidase U32
L2Z33_10840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z33_10850	COG4598	ABC transporter
L2Z33_10855	COG4160	amino acid transport
L2Z33_10860	COG4215	(ABC) transporter
L2Z33_10875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z33_10920	COG1131	(ABC) transporter
L2Z33_10925	COG0842	Transport permease protein
L2Z33_10940	COG0772	Belongs to the SEDS family
L2Z33_10945	COG2951	lytic endotransglycosylase activity
L2Z33_10970	COG2207	Transcriptional regulator
L2Z33_10985	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z33_10990	COG0024	Methionine aminopeptidase
L2Z33_11000	COG2223	nitrite transmembrane transporter activity
L2Z33_11010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z33_11015	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z33_11020	COG1960	acyl-CoA dehydrogenase activity
L2Z33_11035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z33_11040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z33_11045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z33_11065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z33_11070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z33_11075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z33_11110	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z33_11120	COG0174	glutamine synthetase
L2Z33_11135	COG0582	viral genome integration into host DNA
L2Z33_11470	COG3620	sequence-specific DNA binding
L2Z33_11535	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z33_11540	COG0308	aminopeptidase N
L2Z33_11570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z33_11580	COG0302	gtp cyclohydrolase
L2Z33_11605	COG3739	integral membrane protein
L2Z33_11620	COG1169	isochorismate synthase
L2Z33_11630	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z33_11635	COG1132	(ABC) transporter
L2Z33_11640	COG1132	(ABC) transporter
L2Z33_11650	COG3433	isochorismatase activity
L2Z33_11650	COG1535	isochorismatase
L2Z33_11655	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z33_11660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z33_11675	COG4774	siderophore transport
L2Z33_11680	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z33_11685	COG4604	ABC transporter, ATP-binding protein
L2Z33_11690	COG4605	iron ion homeostasis
L2Z33_11695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z33_11700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z33_11715	COG2964	Protein conserved in bacteria
L2Z33_11725	COG1741	Belongs to the pirin family
L2Z33_11745	COG1309	transcriptional regulator
L2Z33_11755	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z33_11760	COG2814	Major facilitator Superfamily
L2Z33_11795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z33_11795	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z33_11800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z33_11810	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_11825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z33_11830	COG0583	DNA-binding transcription factor activity
L2Z33_11835	COG1113	amino acid transport
L2Z33_11855	COG2508	Transcriptional regulator
L2Z33_11855	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z33_11890	COG2879	small protein
L2Z33_11895	COG1966	Carbon starvation protein
L2Z33_11940	COG1067	ATP-dependent peptidase activity
L2Z33_11945	COG0583	DNA-binding transcription factor activity
L2Z33_11970	COG1686	Belongs to the peptidase S11 family
L2Z33_11975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z33_12010	COG0616	signal peptide processing
L2Z33_12015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z33_12025	COG0573	inorganic phosphate transmembrane transporter activity
L2Z33_12030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z33_12035	COG1113	amino acid transport
L2Z33_12040	COG3961	Belongs to the TPP enzyme family
L2Z33_12045	COG1522	sequence-specific DNA binding
L2Z33_12055	COG0076	glutamate decarboxylase activity
L2Z33_12060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z33_12070	COG1309	transcriptional regulator
L2Z33_12085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z33_12120	COG0352	thiamine-phosphate diphosphorylase activity
L2Z33_12145	COG0612	Peptidase, M16
L2Z33_12155	COG1823	symporter activity
L2Z33_12160	COG0583	DNA-binding transcription factor activity
L2Z33_12165	COG0477	Major facilitator Superfamily
L2Z33_12190	COG1187	pseudouridine synthase activity
L2Z33_12205	COG1686	Belongs to the peptidase S11 family
L2Z33_12210	COG1252	NADH dehydrogenase
L2Z33_12220	COG0415	Belongs to the DNA photolyase family
L2Z33_12235	COG1215	transferase activity, transferring glycosyl groups
L2Z33_12265	COG2070	2-Nitropropane dioxygenase
L2Z33_12320	COG0556	nucleotide-excision repair
L2Z33_12340	COG0436	Aminotransferase
L2Z33_12370	COG4221	oxidoreductase activity
L2Z33_12380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z33_12385	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z33_12395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z33_12410	COG0681	Belongs to the peptidase S26 family
L2Z33_12425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z33_12445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z33_12450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z33_12455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z33_12465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z33_12470	COG4208	sulfate ABC transporter
L2Z33_12475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z33_12480	COG0583	DNA-binding transcription factor activity
L2Z33_12485	COG4625	pathogenesis
L2Z33_12500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z33_12515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z33_12525	COG1051	belongs to the nudix hydrolase family
L2Z33_12525	COG1056	cytidyltransferase-related domain
L2Z33_12530	COG1024	Enoyl-CoA hydratase
L2Z33_12540	COG2814	Major facilitator Superfamily
L2Z33_12545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z33_12545	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z33_12565	COG1473	amidohydrolase
L2Z33_12570	COG0824	Thioesterase
L2Z33_12590	COG0823	Involved in the tonB-independent uptake of proteins
L2Z33_12610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z33_12655	COG0628	permease
L2Z33_12665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z33_12670	COG0596	Alpha beta hydrolase
L2Z33_12675	COG0616	signal peptide processing
L2Z33_12675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z33_12685	COG0658	competence protein
L2Z33_12685	COG2333	competence protein COMEC
L2Z33_12690	COG1136	(ABC) transporter
L2Z33_12695	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z33_12730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z33_12750	COG0463	Glycosyl transferase, family 2
L2Z33_12780	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z33_12785	COG1280	lysine exporter protein (LysE YggA)
L2Z33_12795	COG0019	diaminopimelate decarboxylase activity
L2Z33_12805	COG1113	amino acid transport
L2Z33_12820	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z33_12830	COG3339	Conserved Protein
L2Z33_12835	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z33_12840	COG0243	molybdopterin cofactor binding
L2Z33_12845	COG1929	Belongs to the glycerate kinase type-1 family
L2Z33_12860	COG0778	Nitroreductase
L2Z33_12895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z33_12910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z33_12930	COG0741	lytic transglycosylase activity
L2Z33_12950	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z33_12955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z33_12980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z33_12985	COG1597	lipid kinase activity
L2Z33_13000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z33_13005	COG0477	Major facilitator Superfamily
L2Z33_13060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z33_13065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z33_13090	COG0505	Belongs to the CarA family
L2Z33_13110	COG0589	response to stress
L2Z33_13125	COG2843	Capsule synthesis protein
L2Z33_13135	COG2826	transposase and inactivated derivatives, IS30 family
L2Z33_13155	COG2321	neutral zinc metallopeptidase
L2Z33_13160	COG2354	Protein conserved in bacteria
L2Z33_13180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z33_13205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z33_13210	COG1053	succinate dehydrogenase
L2Z33_13215	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z33_13220	COG2009	succinate dehydrogenase
L2Z33_13260	COG2921	Belongs to the UPF0250 family
L2Z33_13265	COG0321	lipoyl(octanoyl) transferase activity
L2Z33_13280	COG0531	amino acid
L2Z33_13290	COG1733	regulation of RNA biosynthetic process
L2Z33_13295	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z33_13300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z33_13300	COG1648	precorrin-2 dehydrogenase activity
L2Z33_13315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z33_13345	COG0671	phosphoesterase, PA-phosphatase related
L2Z33_13350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z33_13360	COG1538	Outer membrane efflux protein
L2Z33_13365	COG0393	Putative heavy-metal-binding
L2Z33_13370	COG0393	Putative heavy-metal-binding
L2Z33_13380	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_13390	COG0525	valine-tRNA ligase activity
L2Z33_13410	COG0583	DNA-binding transcription factor activity
L2Z33_13415	COG0004	ammonium transporteR
L2Z33_13425	COG0642	Histidine kinase
L2Z33_13430	COG0745	RESPONSE REGULATOR receiver
L2Z33_13435	COG2194	sulfuric ester hydrolase activity
L2Z33_13455	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z33_13470	COG2315	Protein conserved in bacteria
L2Z33_13475	COG0142	geranyltranstransferase activity
L2Z33_13480	COG2828	Protein conserved in bacteria
L2Z33_13485	COG1113	amino acid transport
L2Z33_13505	COG2207	Transcriptional regulator
L2Z33_13530	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z33_13550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z33_13560	COG1530	ribonuclease E activity
L2Z33_13565	COG0424	maF-like protein
L2Z33_13570	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z33_13575	COG1792	Involved in formation and maintenance of cell shape
L2Z33_13580	COG1077	Cell shape determining protein MreB Mrl
L2Z33_13585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z33_13595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z33_13625	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z33_13630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z33_13635	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z33_13640	COG1115	amino acid carrier protein
L2Z33_13660	COG2814	Major facilitator Superfamily
L2Z33_13665	COG1289	transmembrane transporter activity
L2Z33_13675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z33_13715	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z33_13720	COG2832	Protein of unknown function (DUF454)
L2Z33_13730	COG5510	response to toxic substance
L2Z33_13750	COG0840	transmembrane signaling receptor activity
L2Z33_13790	COG3422	double-strand break repair
L2Z33_13795	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z33_13800	COG3189	MarR family transcriptional regulator
L2Z33_13810	COG0354	folic acid binding
L2Z33_13815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z33_13825	COG0679	Auxin Efflux Carrier
L2Z33_13830	COG1902	pentaerythritol trinitrate reductase activity
L2Z33_13840	COG2094	Belongs to the DNA glycosylase MPG family
L2Z33_13865	COG1217	gtp-binding protein TYPA
L2Z33_13880	COG0833	amino acid
L2Z33_13885	COG1690	Belongs to the RtcB family
L2Z33_13895	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z33_13895	COG2885	chlorophyll binding
L2Z33_13905	COG0183	Belongs to the thiolase family
L2Z33_13925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z33_13945	COG2207	Transcriptional regulator
L2Z33_13950	COG0183	Belongs to the thiolase family
L2Z33_13980	COG1272	protein, Hemolysin III
L2Z33_13985	COG0477	Major facilitator Superfamily
L2Z33_14000	COG0450	alkyl hydroperoxide reductase
L2Z33_14020	COG0285	dihydrofolate synthase activity
L2Z33_14070	COG2096	Adenosyltransferase
L2Z33_14075	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z33_14090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z33_14095	COG0745	RESPONSE REGULATOR receiver
L2Z33_14100	COG2205	protein histidine kinase activity
L2Z33_14110	COG1960	acyl-CoA dehydrogenase activity
L2Z33_14115	COG1960	acyl-CoA dehydrogenase activity
L2Z33_14185	COG0438	transferase activity, transferring glycosyl groups
L2Z33_14190	COG0463	Glycosyl transferase, family 2
L2Z33_14195	COG0726	polysaccharide deacetylase
L2Z33_14215	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z33_14220	COG2205	protein histidine kinase activity
L2Z33_14250	COG1862	Preprotein translocase
L2Z33_14260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z33_14265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z33_14275	COG3781	membrane
L2Z33_14280	COG0613	PHP domain protein
L2Z33_14290	COG2350	Protein conserved in bacteria
L2Z33_14320	COG1607	acyl-coa hydrolase
L2Z33_14380	COG2199	diguanylate cyclase activity
L2Z33_14395	COG1408	metallophosphoesterase
L2Z33_14400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z33_14410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z33_14430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z33_14435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z33_14450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z33_14460	COG2969	positive regulation of protein catabolic process
L2Z33_14480	COG1960	acyl-CoA dehydrogenase activity
L2Z33_14485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z33_14500	COG1309	transcriptional regulator
L2Z33_14505	COG1960	acyl-CoA dehydrogenase activity
L2Z33_14550	COG1183	phosphatidylcholine synthase activity
L2Z33_14555	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z33_14585	COG0741	lytic transglycosylase activity
L2Z33_14585	COG1196	nuclear chromosome segregation
L2Z33_14585	COG0739	heme binding
L2Z33_14595	COG1702	phosphate starvation-inducible protein PhoH
L2Z33_14630	COG1295	ribonuclease BN
L2Z33_14635	COG0697	spore germination
L2Z33_14640	COG2169	Transcriptional regulator
L2Z33_14645	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z33_14690	COG0557	exoribonuclease II activity
L2Z33_14695	COG0339	signal peptide processing
L2Z33_14700	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z33_14730	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z33_14735	COG1960	acyl-CoA dehydrogenase activity
L2Z33_14890	COG0626	cystathionine gamma-synthase activity
L2Z33_14895	COG0433	COG0433 Predicted ATPase
L2Z33_14900	COG1017	nitric oxide dioxygenase activity
L2Z33_14900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z33_14905	COG1959	2 iron, 2 sulfur cluster binding
L2Z33_14920	COG1301	dicarboxylic acid transport
L2Z33_14925	COG1946	Acyl-CoA thioesterase
L2Z33_14945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z33_14950	COG1040	competence protein
L2Z33_14955	COG0494	nUDIX hydrolase
L2Z33_14965	COG0598	Magnesium transport protein CorA
L2Z33_14975	COG2854	intermembrane phospholipid transfer
L2Z33_14985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z33_14990	COG1127	ABC transporter
L2Z33_15000	COG0513	Belongs to the DEAD box helicase family
L2Z33_15020	COG0408	coproporphyrinogen oxidase activity
L2Z33_15035	COG1960	acyl-CoA dehydrogenase activity
L2Z33_15045	COG1983	PspC domain protein
L2Z33_15050	COG0517	IMP dehydrogenase activity
L2Z33_15100	COG0583	DNA-binding transcription factor activity
L2Z33_15140	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_15150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z33_15155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z33_15160	COG0833	amino acid
L2Z33_15190	COG1192	Involved in chromosome partitioning
L2Z33_15195	COG0628	permease
L2Z33_15205	COG1289	transmembrane transporter activity
L2Z33_15220	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z33_15225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z33_15235	COG0277	FAD linked oxidase domain protein
L2Z33_15240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z33_15265	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z33_15270	COG5380	lipid catabolic process
L2Z33_15290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z33_15340	COG0194	GDP metabolic process
L2Z33_15355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z33_15375	COG3307	-O-antigen
L2Z33_15390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z33_15395	COG1704	LemA family
L2Z33_15405	COG0493	'glutamate synthase
L2Z33_15410	COG0070	glutamate synthase
L2Z33_15410	COG0067	glutamate synthase
L2Z33_15410	COG0069	glutamate synthase activity
L2Z33_15460	COG2226	methyltransferase
L2Z33_15475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z33_15480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z33_15525	COG0833	amino acid
L2Z33_15610	COG0488	(ABC) transporter
L2Z33_15615	COG2873	o-acetylhomoserine
L2Z33_15620	COG4221	oxidoreductase activity
L2Z33_15625	COG0659	secondary active sulfate transmembrane transporter activity
L2Z33_15650	COG0427	acetyl-CoA hydrolase
L2Z33_15680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z33_15710	COG2329	Antibiotic biosynthesis monooxygenase
L2Z33_15725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z33_15790	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z33_15795	COG1733	regulation of RNA biosynthetic process
L2Z33_15830	COG0667	Aldo Keto reductase
L2Z33_15850	COG0583	DNA-binding transcription factor activity
L2Z33_15855	COG2814	Major facilitator Superfamily
L2Z33_15890	COG4372	Transposase
L2Z33_15905	COG1335	isochorismatase
L2Z33_15915	COG1012	belongs to the aldehyde dehydrogenase family
L2Z33_15920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z33_15930	COG1113	amino acid transport
L2Z33_15940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z33_15955	COG2814	Major facilitator Superfamily
L2Z33_15965	COG0351	phosphomethylpyrimidine kinase
L2Z33_15965	COG0352	thiamine-phosphate diphosphorylase activity
L2Z33_15965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z33_15985	COG1309	transcriptional regulator
L2Z33_15990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z33_16010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z33_16020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z33_16025	COG3162	membrane
L2Z33_16030	COG2198	Histidine kinase
L2Z33_16030	COG2205	protein histidine kinase activity
L2Z33_16030	COG0784	Response regulator, receiver
L2Z33_16055	COG1522	sequence-specific DNA binding
L2Z33_16060	COG1335	isochorismatase
L2Z33_16065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z33_16075	COG0668	transmembrane transport
L2Z33_16080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z33_16085	COG1519	Transferase
L2Z33_16090	COG1902	pentaerythritol trinitrate reductase activity
L2Z33_16110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z33_16135	COG0426	domain, Protein
L2Z33_16135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z33_16140	COG4774	siderophore transport
L2Z33_16145	COG2119	membrane
L2Z33_16155	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z33_16165	COG4942	peptidase
L2Z33_16180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z33_16190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z33_16210	COG0189	ligase activity
L2Z33_16230	COG0708	Exodeoxyribonuclease III
L2Z33_16235	COG1393	Belongs to the ArsC family
L2Z33_16250	COG3706	GGDEF domain
L2Z33_16285	COG2351	hydroxyisourate hydrolase activity
L2Z33_16290	COG2233	PERMEase
L2Z33_16300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z33_16310	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z33_16315	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_16325	COG3150	esterase
L2Z33_16345	COG4372	Transposase
L2Z33_16380	COG2918	glutathione biosynthetic process
L2Z33_16395	COG2733	membrane
L2Z33_16400	COG0436	Aminotransferase
L2Z33_16405	COG0534	Mate efflux family protein
L2Z33_16465	COG0753	catalase activity
L2Z33_16510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z33_16515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z33_16525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z33_16570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z33_16585	COG0010	Belongs to the arginase family
L2Z33_16615	COG2188	Transcriptional regulator
L2Z33_16625	COG0523	cobalamin synthesis protein
L2Z33_16635	COG1113	amino acid transport
L2Z33_16645	COG0625	glutathione transferase activity
L2Z33_16665	COG1683	Conserved Protein
L2Z33_16670	COG0534	Mate efflux family protein
L2Z33_16675	COG0385	Bile acid
L2Z33_16680	COG1335	isochorismatase
L2Z33_16685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z33_16705	COG2116	formate transmembrane transporter activity
L2Z33_16710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z33_16715	COG2133	pyrroloquinoline quinone binding
L2Z33_16720	COG2983	Belongs to the UPF0260 family
L2Z33_16730	COG0400	carboxylic ester hydrolase activity
L2Z33_16740	COG1194	a g-specific adenine glycosylase
L2Z33_16755	COG2818	Glycosylase
L2Z33_16760	COG1064	alcohol dehydrogenase
L2Z33_16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z33_16780	COG0583	DNA-binding transcription factor activity
L2Z33_16785	COG0656	L-ascorbic acid biosynthetic process
L2Z33_16790	COG2814	Major facilitator Superfamily
L2Z33_16825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z33_16840	COG2233	PERMEase
L2Z33_16845	COG0583	DNA-binding transcription factor activity
L2Z33_16870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L2Z33_16880	COG0733	neurotransmitter:sodium symporter activity
L2Z33_16920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z33_16925	COG0657	acetylesterase activity
L2Z33_16945	COG0583	DNA-binding transcription factor activity
L2Z33_16975	COG2951	lytic endotransglycosylase activity
L2Z33_16980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z33_16995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z33_17005	COG0671	phosphoesterase, PA-phosphatase related
L2Z33_17010	COG0861	Integral membrane protein TerC family
L2Z33_17020	COG0754	glutathionylspermidine amidase activity
L2Z33_17030	COG0402	S-adenosylhomocysteine deaminase activity
L2Z33_17045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z33_17050	COG1230	cation diffusion facilitator family transporter
L2Z33_17065	COG0706	membrane insertase activity
L2Z33_17090	COG0592	DNA-directed DNA polymerase activity
L2Z33_17100	COG0187	DNA topoisomerase II activity
L2Z33_17110	COG0586	Pfam SNARE associated Golgi protein
L2Z33_17115	COG0488	(ABC) transporter
L2Z33_17140	COG0596	Alpha beta hydrolase
L2Z33_17145	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z33_17150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z33_17190	COG1047	Peptidyl-prolyl cis-trans
L2Z33_17200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z33_17205	COG0196	riboflavin kinase activity
L2Z33_17215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z33_17220	COG1309	transcriptional regulator
L2Z33_17225	COG1116	anion transmembrane transporter activity
L2Z33_17230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z33_17235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z33_17240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z33_17245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z33_17265	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z33_17270	COG0546	phosphoglycolate phosphatase activity
L2Z33_17325	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z33_17330	COG0728	peptidoglycan biosynthetic process
L2Z33_17360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z33_17390	COG0438	transferase activity, transferring glycosyl groups
L2Z33_17410	COG1216	Glycosyl transferase, family 2
L2Z33_17415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z33_17420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z33_17435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z33_17445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z33_17455	COG2186	Transcriptional regulator
L2Z33_17465	COG0277	FAD linked oxidase domain protein
L2Z33_17470	COG1448	Aminotransferase
L2Z33_17480	COG1802	Transcriptional regulator
L2Z33_17495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z33_17540	COG0564	pseudouridine synthase activity
L2Z33_17580	COG0251	oxidation-reduction process
L2Z33_17585	COG1113	amino acid transport
L2Z33_17590	COG1113	amino acid transport
L2Z33_17610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z33_17615	COG1960	acyl-CoA dehydrogenase activity
L2Z33_17620	COG1024	Enoyl-CoA hydratase
L2Z33_17625	COG1024	Enoyl-CoA hydratase
L2Z33_17630	COG0477	Major facilitator Superfamily
L2Z33_17635	COG3916	Acyl-homoserine-lactone synthase
L2Z33_17645	COG2197	response regulator
L2Z33_17655	COG1960	acyl-CoA dehydrogenase activity
L2Z33_17660	COG3321	synthase
L2Z33_17660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z33_17660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z33_17660	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z33_17700	COG0271	Belongs to the BolA IbaG family
L2Z33_17710	COG1192	Involved in chromosome partitioning
L2Z33_17725	COG0586	Pfam SNARE associated Golgi protein
L2Z33_17730	COG2259	Doxx family
L2Z33_17735	COG4399	Belongs to the UPF0754 family
L2Z33_17740	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z33_17740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z33_17795	COG0281	malic enzyme
L2Z33_17800	COG2837	iron assimilation
L2Z33_17805	COG1280	lysine exporter protein (LysE YggA)
L2Z33_17810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z33_17815	COG1121	(ABC) transporter
L2Z33_17885	COG0386	Belongs to the glutathione peroxidase family
L2Z33_17900	COG1309	transcriptional regulator
L2Z33_17905	COG0697	spore germination
L2Z33_17915	COG0758	DNA mediated transformation
L2Z33_17985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z33_17995	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z33_18035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z33_18045	COG2814	Major facilitator Superfamily
L2Z33_18055	COG1253	flavin adenine dinucleotide binding
L2Z33_18060	COG3012	SEC-C Motif Domain Protein
L2Z33_18065	COG2860	membrane
L2Z33_18070	COG0477	Major facilitator Superfamily
L2Z33_18080	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z33_18095	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z33_18115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z33_18170	COG0589	response to stress
L2Z33_18175	COG0659	secondary active sulfate transmembrane transporter activity
L2Z33_18185	COG1002	Type II restriction enzyme, methylase subunits
L2Z33_18190	COG1061	Type III restriction enzyme res subunit
L2Z33_18225	COG0347	Belongs to the P(II) protein family
L2Z33_18230	COG0004	ammonium transporteR
L2Z33_18240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z33_18240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z33_18280	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z33_18285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z33_18290	COG0793	Belongs to the peptidase S41A family
L2Z33_18305	COG2197	response regulator
L2Z33_18315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z33_18325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z33_18330	COG4974	Belongs to the 'phage' integrase family
L2Z33_18355	COG0772	Belongs to the SEDS family
L2Z33_18360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z33_18365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z33_18370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z33_18395	COG0697	spore germination
L2Z33_18400	COG1538	Outer membrane efflux protein
L2Z33_18420	COG3275	phosphorelay sensor kinase activity
L2Z33_18430	COG0181	hydroxymethylbilane synthase activity
L2Z33_18475	COG1716	ATPase activity
L2Z33_18480	COG0546	phosphoglycolate phosphatase activity
L2Z33_18580	COG0596	Alpha beta hydrolase
L2Z33_18585	COG2056	Na+-H+ antiporter family
L2Z33_18600	COG0326	Molecular chaperone. Has ATPase activity
L2Z33_18615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z33_18680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z33_18685	COG2169	Transcriptional regulator
L2Z33_18685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z33_18715	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z33_18725	COG0497	DNA recombination
L2Z33_18740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z33_18750	COG0237	dephospho-CoA kinase activity
L2Z33_18755	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z33_18805	COG0195	Participates in both transcription termination and antitermination
L2Z33_18820	COG1320	monovalent cation:proton antiporter activity
L2Z33_18825	COG2212	antiporter activity
L2Z33_18830	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z33_18835	COG0651	ATP synthesis coupled electron transport
L2Z33_18840	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z33_18845	COG2111	Na H antiporter
L2Z33_18845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z33_18860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z33_18865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z33_18880	COG2226	methyltransferase