locus-tag	class	description
L2Z34_00055	COG5410	chromosome segregation
L2Z34_00225	COG0069	glutamate synthase activity
L2Z34_00245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z34_00255	COG1454	alcohol dehydrogenase
L2Z34_00260	COG0824	Thioesterase
L2Z34_00270	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z34_00285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z34_00290	COG2030	dehydratase
L2Z34_00300	COG0183	Belongs to the thiolase family
L2Z34_00310	COG0583	DNA-binding transcription factor activity
L2Z34_00315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z34_00325	COG1522	sequence-specific DNA binding
L2Z34_00330	COG3135	benzoate transporter
L2Z34_00350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z34_00375	COG0589	response to stress
L2Z34_00380	COG0488	(ABC) transporter
L2Z34_00400	COG4773	Receptor
L2Z34_00435	COG0668	transmembrane transport
L2Z34_00445	COG1309	transcriptional regulator
L2Z34_00465	COG1605	Chorismate mutase
L2Z34_00495	COG0308	aminopeptidase N
L2Z34_00515	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z34_00525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z34_00530	COG1454	alcohol dehydrogenase
L2Z34_00550	COG0531	amino acid
L2Z34_00555	COG4303	Ethanolamine ammonia lyase large subunit
L2Z34_00560	COG4302	ethanolamine ammonia-lyase activity
L2Z34_00565	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z34_00565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z34_00570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z34_00580	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z34_00595	COG0697	spore germination
L2Z34_00600	COG1923	regulation of RNA biosynthetic process
L2Z34_00610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z34_00615	COG0802	atpase or kinase
L2Z34_00635	COG1187	pseudouridine synthase activity
L2Z34_00650	COG0583	DNA-binding transcription factor activity
L2Z34_00665	COG2814	Major facilitator Superfamily
L2Z34_00670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z34_00695	COG0729	surface antigen
L2Z34_00715	COG0174	glutamine synthetase
L2Z34_00720	COG0745	RESPONSE REGULATOR receiver
L2Z34_00725	COG2205	protein histidine kinase activity
L2Z34_00735	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z34_00740	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z34_00765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z34_00770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z34_00775	COG1960	acyl-CoA dehydrogenase activity
L2Z34_00790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z34_00795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z34_00815	COG0583	DNA-binding transcription factor activity
L2Z34_00830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z34_00840	COG3658	cytochrome
L2Z34_00845	COG1215	transferase activity, transferring glycosyl groups
L2Z34_00850	COG0726	polysaccharide deacetylase
L2Z34_00850	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z34_00875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z34_00880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z34_00890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z34_00915	COG0305	Participates in initiation and elongation during chromosome replication
L2Z34_00920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z34_00930	COG1305	Transglutaminase-like
L2Z34_00940	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z34_00970	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z34_00975	COG0138	bifunctional purine biosynthesis protein purh
L2Z34_00980	COG0151	Belongs to the GarS family
L2Z34_00985	COG1464	Belongs to the NlpA lipoprotein family
L2Z34_00990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z34_00995	COG2011	ABC-type metal ion transport system permease component
L2Z34_01000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z34_01010	COG1301	dicarboxylic acid transport
L2Z34_01050	COG2433	Pfam Transposase IS66
L2Z34_01060	COG3173	Aminoglycoside phosphotransferase
L2Z34_01065	COG0488	(ABC) transporter
L2Z34_01095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z34_01095	COG3008	intermembrane lipid transfer
L2Z34_01100	COG2995	paraquat-inducible protein a
L2Z34_01110	COG2985	domain, Protein
L2Z34_01140	COG0477	Major facilitator Superfamily
L2Z34_01195	COG2186	Transcriptional regulator
L2Z34_01205	COG0786	glutamate:sodium symporter activity
L2Z34_01210	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z34_01235	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z34_01335	COG1610	YqeY-like protein
L2Z34_01340	COG4783	chaperone-mediated protein folding
L2Z34_01350	COG3676	manually curated
L2Z34_01375	COG1286	toxin biosynthetic process
L2Z34_01405	COG0778	Nitroreductase
L2Z34_01415	COG0513	Belongs to the DEAD box helicase family
L2Z34_01440	COG2363	Small membrane protein
L2Z34_01470	COG1234	tRNA 3'-trailer cleavage
L2Z34_01475	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z34_01485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z34_01495	COG2819	hydrolase of the alpha beta superfamily
L2Z34_01500	COG1960	acyl-CoA dehydrogenase activity
L2Z34_01505	COG1301	dicarboxylic acid transport
L2Z34_01510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z34_01515	COG3139	Protein of unknown function (DUF1315)
L2Z34_01520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z34_01525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z34_01535	COG0494	nUDIX hydrolase
L2Z34_01545	COG0642	Histidine kinase
L2Z34_01560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z34_01570	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z34_01585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z34_01590	COG0826	peptidase U32
L2Z34_01595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z34_01605	COG4598	ABC transporter
L2Z34_01610	COG4160	amino acid transport
L2Z34_01615	COG4215	(ABC) transporter
L2Z34_01630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z34_01675	COG1131	(ABC) transporter
L2Z34_01680	COG0842	Transport permease protein
L2Z34_01695	COG0772	Belongs to the SEDS family
L2Z34_01700	COG2951	lytic endotransglycosylase activity
L2Z34_01725	COG2207	Transcriptional regulator
L2Z34_01740	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z34_01745	COG0024	Methionine aminopeptidase
L2Z34_01755	COG2223	nitrite transmembrane transporter activity
L2Z34_01765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z34_01770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z34_01800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z34_01805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z34_01810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z34_01830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z34_01835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z34_01840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z34_01875	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z34_01885	COG0174	glutamine synthetase
L2Z34_01900	COG0582	viral genome integration into host DNA
L2Z34_01995	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z34_02095	COG5410	chromosome segregation
L2Z34_02210	COG0305	Participates in initiation and elongation during chromosome replication
L2Z34_02315	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z34_02320	COG0308	aminopeptidase N
L2Z34_02350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z34_02360	COG0302	gtp cyclohydrolase
L2Z34_02385	COG3739	integral membrane protein
L2Z34_02400	COG1169	isochorismate synthase
L2Z34_02410	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z34_02415	COG1132	(ABC) transporter
L2Z34_02420	COG1132	(ABC) transporter
L2Z34_02435	COG3433	isochorismatase activity
L2Z34_02435	COG1535	isochorismatase
L2Z34_02440	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z34_02445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z34_02455	COG4774	siderophore transport
L2Z34_02460	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z34_02465	COG4604	ABC transporter, ATP-binding protein
L2Z34_02470	COG4605	iron ion homeostasis
L2Z34_02475	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z34_02480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z34_02495	COG2964	Protein conserved in bacteria
L2Z34_02505	COG1741	Belongs to the pirin family
L2Z34_02525	COG1309	transcriptional regulator
L2Z34_02535	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z34_02540	COG2814	Major facilitator Superfamily
L2Z34_02575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z34_02575	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z34_02580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z34_02590	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_02600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z34_02605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z34_02610	COG0583	DNA-binding transcription factor activity
L2Z34_02615	COG1113	amino acid transport
L2Z34_02635	COG2508	Transcriptional regulator
L2Z34_02635	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z34_02670	COG2879	small protein
L2Z34_02675	COG1966	Carbon starvation protein
L2Z34_02720	COG1067	ATP-dependent peptidase activity
L2Z34_02725	COG0583	DNA-binding transcription factor activity
L2Z34_02750	COG1686	Belongs to the peptidase S11 family
L2Z34_02755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z34_02785	COG3328	transposase activity
L2Z34_02800	COG0616	signal peptide processing
L2Z34_02805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z34_02815	COG0573	inorganic phosphate transmembrane transporter activity
L2Z34_02820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z34_02825	COG1113	amino acid transport
L2Z34_02830	COG3961	Belongs to the TPP enzyme family
L2Z34_02835	COG1522	sequence-specific DNA binding
L2Z34_02845	COG0076	glutamate decarboxylase activity
L2Z34_02850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z34_02860	COG1309	transcriptional regulator
L2Z34_02875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z34_02910	COG0352	thiamine-phosphate diphosphorylase activity
L2Z34_02935	COG0612	Peptidase, M16
L2Z34_02955	COG1823	symporter activity
L2Z34_02960	COG0583	DNA-binding transcription factor activity
L2Z34_02965	COG0477	Major facilitator Superfamily
L2Z34_02990	COG1187	pseudouridine synthase activity
L2Z34_03005	COG1686	Belongs to the peptidase S11 family
L2Z34_03010	COG1252	NADH dehydrogenase
L2Z34_03020	COG0415	Belongs to the DNA photolyase family
L2Z34_03035	COG1215	transferase activity, transferring glycosyl groups
L2Z34_03065	COG2070	2-Nitropropane dioxygenase
L2Z34_03120	COG0556	nucleotide-excision repair
L2Z34_03140	COG0436	Aminotransferase
L2Z34_03170	COG4221	oxidoreductase activity
L2Z34_03180	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z34_03185	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z34_03195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z34_03210	COG0681	Belongs to the peptidase S26 family
L2Z34_03225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z34_03250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z34_03255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z34_03260	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z34_03270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z34_03275	COG4208	sulfate ABC transporter
L2Z34_03280	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z34_03285	COG0583	DNA-binding transcription factor activity
L2Z34_03295	COG3676	manually curated
L2Z34_03315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z34_03330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z34_03340	COG1056	cytidyltransferase-related domain
L2Z34_03340	COG1051	belongs to the nudix hydrolase family
L2Z34_03345	COG1024	Enoyl-CoA hydratase
L2Z34_03355	COG2814	Major facilitator Superfamily
L2Z34_03360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z34_03360	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z34_03380	COG1473	amidohydrolase
L2Z34_03385	COG0824	Thioesterase
L2Z34_03405	COG0823	Involved in the tonB-independent uptake of proteins
L2Z34_03425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z34_03460	COG0628	permease
L2Z34_03470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z34_03475	COG0596	Alpha beta hydrolase
L2Z34_03480	COG0616	signal peptide processing
L2Z34_03480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z34_03490	COG2333	competence protein COMEC
L2Z34_03490	COG0658	competence protein
L2Z34_03495	COG1136	(ABC) transporter
L2Z34_03500	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z34_03535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z34_03555	COG0463	Glycosyl transferase, family 2
L2Z34_03585	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z34_03590	COG1280	lysine exporter protein (LysE YggA)
L2Z34_03600	COG0019	diaminopimelate decarboxylase activity
L2Z34_03610	COG1113	amino acid transport
L2Z34_03625	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z34_03635	COG3339	Conserved Protein
L2Z34_03640	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z34_03645	COG0243	molybdopterin cofactor binding
L2Z34_03650	COG1929	Belongs to the glycerate kinase type-1 family
L2Z34_03665	COG0778	Nitroreductase
L2Z34_03680	COG3676	manually curated
L2Z34_03710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z34_03725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z34_03745	COG0741	lytic transglycosylase activity
L2Z34_03765	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z34_03795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z34_03800	COG1597	lipid kinase activity
L2Z34_03815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z34_03820	COG0477	Major facilitator Superfamily
L2Z34_03870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z34_03875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z34_03900	COG0505	Belongs to the CarA family
L2Z34_03920	COG0589	response to stress
L2Z34_03935	COG2843	Capsule synthesis protein
L2Z34_03955	COG2321	neutral zinc metallopeptidase
L2Z34_03960	COG2354	Protein conserved in bacteria
L2Z34_03980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z34_04005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z34_04010	COG1053	succinate dehydrogenase
L2Z34_04015	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z34_04020	COG2009	succinate dehydrogenase
L2Z34_04060	COG2921	Belongs to the UPF0250 family
L2Z34_04065	COG0321	lipoyl(octanoyl) transferase activity
L2Z34_04080	COG0531	amino acid
L2Z34_04090	COG1733	regulation of RNA biosynthetic process
L2Z34_04095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z34_04100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z34_04100	COG1648	precorrin-2 dehydrogenase activity
L2Z34_04115	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z34_04145	COG0671	phosphoesterase, PA-phosphatase related
L2Z34_04150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z34_04160	COG1538	Outer membrane efflux protein
L2Z34_04165	COG0393	Putative heavy-metal-binding
L2Z34_04170	COG0393	Putative heavy-metal-binding
L2Z34_04180	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_04190	COG0525	valine-tRNA ligase activity
L2Z34_04210	COG0583	DNA-binding transcription factor activity
L2Z34_04215	COG0004	ammonium transporteR
L2Z34_04225	COG0642	Histidine kinase
L2Z34_04230	COG0745	RESPONSE REGULATOR receiver
L2Z34_04235	COG2194	sulfuric ester hydrolase activity
L2Z34_04255	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z34_04270	COG2315	Protein conserved in bacteria
L2Z34_04275	COG0142	geranyltranstransferase activity
L2Z34_04280	COG2828	Protein conserved in bacteria
L2Z34_04285	COG1113	amino acid transport
L2Z34_04305	COG2207	Transcriptional regulator
L2Z34_04330	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z34_04340	COG0560	Phosphoserine phosphatase
L2Z34_04350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z34_04360	COG1530	ribonuclease E activity
L2Z34_04365	COG0424	maF-like protein
L2Z34_04370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z34_04375	COG1792	Involved in formation and maintenance of cell shape
L2Z34_04380	COG1077	Cell shape determining protein MreB Mrl
L2Z34_04385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z34_04395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z34_04435	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z34_04440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z34_04445	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z34_04450	COG1115	amino acid carrier protein
L2Z34_04470	COG2814	Major facilitator Superfamily
L2Z34_04475	COG1289	transmembrane transporter activity
L2Z34_04485	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z34_04525	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z34_04530	COG2832	Protein of unknown function (DUF454)
L2Z34_04540	COG5510	response to toxic substance
L2Z34_04560	COG0840	transmembrane signaling receptor activity
L2Z34_04605	COG3422	double-strand break repair
L2Z34_04610	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z34_04615	COG3189	MarR family transcriptional regulator
L2Z34_04625	COG0354	folic acid binding
L2Z34_04630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z34_04640	COG0679	Auxin Efflux Carrier
L2Z34_04645	COG1902	pentaerythritol trinitrate reductase activity
L2Z34_04665	COG2094	Belongs to the DNA glycosylase MPG family
L2Z34_04690	COG1217	gtp-binding protein TYPA
L2Z34_04695	COG2233	PERMEase
L2Z34_04705	COG0833	amino acid
L2Z34_04710	COG1690	Belongs to the RtcB family
L2Z34_04720	COG2885	chlorophyll binding
L2Z34_04720	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z34_04730	COG0183	Belongs to the thiolase family
L2Z34_04750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z34_04770	COG2207	Transcriptional regulator
L2Z34_04775	COG0183	Belongs to the thiolase family
L2Z34_04805	COG1272	protein, Hemolysin III
L2Z34_04810	COG0477	Major facilitator Superfamily
L2Z34_04825	COG0450	alkyl hydroperoxide reductase
L2Z34_04845	COG0285	dihydrofolate synthase activity
L2Z34_04895	COG2096	Adenosyltransferase
L2Z34_04915	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z34_04920	COG0745	RESPONSE REGULATOR receiver
L2Z34_04925	COG2205	protein histidine kinase activity
L2Z34_04935	COG1960	acyl-CoA dehydrogenase activity
L2Z34_04940	COG1960	acyl-CoA dehydrogenase activity
L2Z34_04945	COG0583	DNA-binding transcription factor activity
L2Z34_04950	COG0625	glutathione transferase activity
L2Z34_05015	COG0438	transferase activity, transferring glycosyl groups
L2Z34_05020	COG0463	Glycosyl transferase, family 2
L2Z34_05025	COG0726	polysaccharide deacetylase
L2Z34_05045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z34_05050	COG2205	protein histidine kinase activity
L2Z34_05080	COG1862	Preprotein translocase
L2Z34_05090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z34_05095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z34_05105	COG3781	membrane
L2Z34_05110	COG0613	PHP domain protein
L2Z34_05120	COG2350	Protein conserved in bacteria
L2Z34_05150	COG1607	acyl-coa hydrolase
L2Z34_05210	COG2199	diguanylate cyclase activity
L2Z34_05220	COG1408	metallophosphoesterase
L2Z34_05225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z34_05235	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z34_05255	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z34_05260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z34_05275	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z34_05285	COG2969	positive regulation of protein catabolic process
L2Z34_05305	COG1960	acyl-CoA dehydrogenase activity
L2Z34_05310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z34_05325	COG1309	transcriptional regulator
L2Z34_05330	COG1960	acyl-CoA dehydrogenase activity
L2Z34_05375	COG1183	phosphatidylcholine synthase activity
L2Z34_05380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z34_05410	COG0739	heme binding
L2Z34_05410	COG0741	lytic transglycosylase activity
L2Z34_05410	COG1196	nuclear chromosome segregation
L2Z34_05420	COG1702	phosphate starvation-inducible protein PhoH
L2Z34_05455	COG1295	ribonuclease BN
L2Z34_05460	COG0697	spore germination
L2Z34_05465	COG2169	Transcriptional regulator
L2Z34_05470	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z34_05515	COG0557	exoribonuclease II activity
L2Z34_05520	COG0339	signal peptide processing
L2Z34_05525	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z34_05555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z34_05560	COG1960	acyl-CoA dehydrogenase activity
L2Z34_05715	COG0626	cystathionine gamma-synthase activity
L2Z34_05720	COG0433	COG0433 Predicted ATPase
L2Z34_05725	COG1017	nitric oxide dioxygenase activity
L2Z34_05725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z34_05730	COG1959	2 iron, 2 sulfur cluster binding
L2Z34_05745	COG1301	dicarboxylic acid transport
L2Z34_05750	COG1946	Acyl-CoA thioesterase
L2Z34_05770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z34_05775	COG1040	competence protein
L2Z34_05780	COG0494	nUDIX hydrolase
L2Z34_05790	COG0598	Magnesium transport protein CorA
L2Z34_05800	COG2854	intermembrane phospholipid transfer
L2Z34_05810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z34_05815	COG1127	ABC transporter
L2Z34_05825	COG0513	Belongs to the DEAD box helicase family
L2Z34_05845	COG0408	coproporphyrinogen oxidase activity
L2Z34_05860	COG1960	acyl-CoA dehydrogenase activity
L2Z34_05870	COG1983	PspC domain protein
L2Z34_05875	COG0517	IMP dehydrogenase activity
L2Z34_05920	COG0583	DNA-binding transcription factor activity
L2Z34_05960	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_05970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z34_05975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z34_05980	COG0833	amino acid
L2Z34_06010	COG1192	Involved in chromosome partitioning
L2Z34_06015	COG0628	permease
L2Z34_06030	COG3676	manually curated
L2Z34_06050	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z34_06055	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z34_06065	COG0277	FAD linked oxidase domain protein
L2Z34_06070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z34_06085	COG3676	manually curated
L2Z34_06100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z34_06105	COG5380	lipid catabolic process
L2Z34_06125	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z34_06175	COG0194	GDP metabolic process
L2Z34_06190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z34_06210	COG3307	-O-antigen
L2Z34_06230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z34_06235	COG1704	LemA family
L2Z34_06245	COG0493	'glutamate synthase
L2Z34_06250	COG0070	glutamate synthase
L2Z34_06250	COG0069	glutamate synthase activity
L2Z34_06250	COG0067	glutamate synthase
L2Z34_06300	COG2226	methyltransferase
L2Z34_06315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z34_06320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z34_06365	COG0833	amino acid
L2Z34_06450	COG0488	(ABC) transporter
L2Z34_06455	COG2873	o-acetylhomoserine
L2Z34_06460	COG4221	oxidoreductase activity
L2Z34_06465	COG0659	secondary active sulfate transmembrane transporter activity
L2Z34_06490	COG0427	acetyl-CoA hydrolase
L2Z34_06520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z34_06550	COG2329	Antibiotic biosynthesis monooxygenase
L2Z34_06565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z34_06630	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z34_06635	COG1733	regulation of RNA biosynthetic process
L2Z34_06670	COG0667	Aldo Keto reductase
L2Z34_06690	COG3676	manually curated
L2Z34_06700	COG0583	DNA-binding transcription factor activity
L2Z34_06705	COG2814	Major facilitator Superfamily
L2Z34_06735	COG1335	isochorismatase
L2Z34_06745	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_06750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z34_06760	COG1113	amino acid transport
L2Z34_06770	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z34_06785	COG2814	Major facilitator Superfamily
L2Z34_06795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z34_06795	COG0352	thiamine-phosphate diphosphorylase activity
L2Z34_06795	COG0351	phosphomethylpyrimidine kinase
L2Z34_06815	COG1309	transcriptional regulator
L2Z34_06820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z34_06830	COG3676	manually curated
L2Z34_06850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z34_06860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z34_06865	COG3162	membrane
L2Z34_06870	COG2205	protein histidine kinase activity
L2Z34_06870	COG2198	Histidine kinase
L2Z34_06870	COG0784	Response regulator, receiver
L2Z34_06895	COG3328	transposase activity
L2Z34_06900	COG1522	sequence-specific DNA binding
L2Z34_06905	COG1335	isochorismatase
L2Z34_06910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z34_06920	COG0668	transmembrane transport
L2Z34_06925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z34_06930	COG1519	Transferase
L2Z34_06935	COG1902	pentaerythritol trinitrate reductase activity
L2Z34_06955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z34_06980	COG0426	domain, Protein
L2Z34_06980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z34_06985	COG4774	siderophore transport
L2Z34_06990	COG2119	membrane
L2Z34_07000	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z34_07010	COG4942	peptidase
L2Z34_07025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z34_07035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z34_07055	COG0189	ligase activity
L2Z34_07075	COG0708	Exodeoxyribonuclease III
L2Z34_07080	COG1393	Belongs to the ArsC family
L2Z34_07095	COG3706	GGDEF domain
L2Z34_07130	COG2351	hydroxyisourate hydrolase activity
L2Z34_07135	COG2233	PERMEase
L2Z34_07145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z34_07155	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z34_07160	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_07170	COG3150	esterase
L2Z34_07185	COG1388	LysM domain
L2Z34_07185	COG0791	NLP P60 protein
L2Z34_07200	COG2918	glutathione biosynthetic process
L2Z34_07215	COG2733	membrane
L2Z34_07220	COG0436	Aminotransferase
L2Z34_07225	COG0534	Mate efflux family protein
L2Z34_07325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z34_07330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z34_07340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z34_07410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z34_07420	COG0534	Mate efflux family protein
L2Z34_07435	COG4774	siderophore transport
L2Z34_07440	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z34_07460	COG0019	diaminopimelate decarboxylase activity
L2Z34_07465	COG3486	L-lysine 6-monooxygenase (NADPH) activity
L2Z34_07470	COG3676	manually curated
L2Z34_07480	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z34_07485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z34_07500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z34_07505	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_07515	COG1169	isochorismate synthase
L2Z34_07540	COG0084	hydrolase, TatD family'
L2Z34_07550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z34_07565	COG0010	Belongs to the arginase family
L2Z34_07595	COG2188	Transcriptional regulator
L2Z34_07605	COG0523	cobalamin synthesis protein
L2Z34_07615	COG1113	amino acid transport
L2Z34_07625	COG0625	glutathione transferase activity
L2Z34_07645	COG1683	Conserved Protein
L2Z34_07650	COG0534	Mate efflux family protein
L2Z34_07655	COG0385	Bile acid
L2Z34_07660	COG1335	isochorismatase
L2Z34_07665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z34_07685	COG2116	formate transmembrane transporter activity
L2Z34_07690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z34_07695	COG2133	pyrroloquinoline quinone binding
L2Z34_07700	COG2983	Belongs to the UPF0260 family
L2Z34_07720	COG1194	a g-specific adenine glycosylase
L2Z34_07735	COG2818	Glycosylase
L2Z34_07740	COG1064	alcohol dehydrogenase
L2Z34_07745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z34_07760	COG0583	DNA-binding transcription factor activity
L2Z34_07765	COG0656	L-ascorbic acid biosynthetic process
L2Z34_07770	COG2814	Major facilitator Superfamily
L2Z34_07805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z34_07820	COG2233	PERMEase
L2Z34_07860	COG0733	neurotransmitter:sodium symporter activity
L2Z34_07900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z34_07905	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z34_07910	COG0596	Alpha beta hydrolase
L2Z34_07935	COG0488	(ABC) transporter
L2Z34_07940	COG0586	Pfam SNARE associated Golgi protein
L2Z34_07950	COG0187	DNA topoisomerase II activity
L2Z34_07960	COG0592	DNA-directed DNA polymerase activity
L2Z34_07985	COG0706	membrane insertase activity
L2Z34_08000	COG1230	cation diffusion facilitator family transporter
L2Z34_08005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z34_08020	COG0402	S-adenosylhomocysteine deaminase activity
L2Z34_08030	COG0754	glutathionylspermidine amidase activity
L2Z34_08040	COG0861	Integral membrane protein TerC family
L2Z34_08045	COG0671	phosphoesterase, PA-phosphatase related
L2Z34_08055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z34_08070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z34_08075	COG2951	lytic endotransglycosylase activity
L2Z34_08105	COG0583	DNA-binding transcription factor activity
L2Z34_08125	COG0657	acetylesterase activity
L2Z34_08130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z34_08170	COG1047	Peptidyl-prolyl cis-trans
L2Z34_08180	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z34_08185	COG0196	riboflavin kinase activity
L2Z34_08195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z34_08200	COG1309	transcriptional regulator
L2Z34_08205	COG1116	anion transmembrane transporter activity
L2Z34_08210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z34_08215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z34_08220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z34_08225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z34_08245	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_08250	COG0546	phosphoglycolate phosphatase activity
L2Z34_08305	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z34_08310	COG0728	peptidoglycan biosynthetic process
L2Z34_08335	COG1596	polysaccharide export
L2Z34_08340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z34_08400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z34_08405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z34_08410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z34_08425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z34_08430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z34_08440	COG2186	Transcriptional regulator
L2Z34_08450	COG0277	FAD linked oxidase domain protein
L2Z34_08455	COG1448	Aminotransferase
L2Z34_08465	COG1802	Transcriptional regulator
L2Z34_08480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z34_08540	COG0564	pseudouridine synthase activity
L2Z34_08580	COG0251	oxidation-reduction process
L2Z34_08585	COG1113	amino acid transport
L2Z34_08590	COG1113	amino acid transport
L2Z34_08610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z34_08615	COG1960	acyl-CoA dehydrogenase activity
L2Z34_08620	COG1024	Enoyl-CoA hydratase
L2Z34_08625	COG1024	Enoyl-CoA hydratase
L2Z34_08630	COG0477	Major facilitator Superfamily
L2Z34_08635	COG3916	Acyl-homoserine-lactone synthase
L2Z34_08645	COG2197	response regulator
L2Z34_08655	COG1960	acyl-CoA dehydrogenase activity
L2Z34_08660	COG3321	synthase
L2Z34_08660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z34_08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z34_08660	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z34_08680	COG2267	carboxylic ester hydrolase activity
L2Z34_08700	COG0271	Belongs to the BolA IbaG family
L2Z34_08710	COG1192	Involved in chromosome partitioning
L2Z34_08725	COG0586	Pfam SNARE associated Golgi protein
L2Z34_08730	COG2259	Doxx family
L2Z34_08735	COG4399	Belongs to the UPF0754 family
L2Z34_08740	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z34_08740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z34_08785	COG0281	malic enzyme
L2Z34_08795	COG2837	iron assimilation
L2Z34_08800	COG1280	lysine exporter protein (LysE YggA)
L2Z34_08805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z34_08810	COG1121	(ABC) transporter
L2Z34_08875	COG0386	Belongs to the glutathione peroxidase family
L2Z34_08890	COG1309	transcriptional regulator
L2Z34_08895	COG0697	spore germination
L2Z34_08905	COG0758	DNA mediated transformation
L2Z34_08975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z34_08985	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z34_09025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z34_09045	COG1253	flavin adenine dinucleotide binding
L2Z34_09055	COG2860	membrane
L2Z34_09060	COG0477	Major facilitator Superfamily
L2Z34_09070	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z34_09085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z34_09105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z34_09160	COG0589	response to stress
L2Z34_09165	COG0659	secondary active sulfate transmembrane transporter activity
L2Z34_09175	COG1002	Type II restriction enzyme, methylase subunits
L2Z34_09180	COG1061	Type III restriction enzyme res subunit
L2Z34_09255	COG0347	Belongs to the P(II) protein family
L2Z34_09260	COG0004	ammonium transporteR
L2Z34_09270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z34_09270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z34_09310	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z34_09315	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z34_09320	COG0793	Belongs to the peptidase S41A family
L2Z34_09335	COG2197	response regulator
L2Z34_09345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z34_09355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z34_09360	COG4974	Belongs to the 'phage' integrase family
L2Z34_09385	COG0772	Belongs to the SEDS family
L2Z34_09390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z34_09395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z34_09400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z34_09425	COG0697	spore germination
L2Z34_09430	COG1538	Outer membrane efflux protein
L2Z34_09450	COG3275	phosphorelay sensor kinase activity
L2Z34_09460	COG0181	hydroxymethylbilane synthase activity
L2Z34_09505	COG1716	ATPase activity
L2Z34_09510	COG0546	phosphoglycolate phosphatase activity
L2Z34_09605	COG0596	Alpha beta hydrolase
L2Z34_09610	COG2056	Na+-H+ antiporter family
L2Z34_09625	COG0326	Molecular chaperone. Has ATPase activity
L2Z34_09640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z34_09705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z34_09710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z34_09710	COG2169	Transcriptional regulator
L2Z34_09740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z34_09750	COG0497	DNA recombination
L2Z34_09765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z34_09775	COG0237	dephospho-CoA kinase activity
L2Z34_09780	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z34_09830	COG0195	Participates in both transcription termination and antitermination
L2Z34_09845	COG1320	monovalent cation:proton antiporter activity
L2Z34_09850	COG2212	antiporter activity
L2Z34_09855	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z34_09860	COG0651	ATP synthesis coupled electron transport
L2Z34_09865	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z34_09870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z34_09870	COG2111	Na H antiporter
L2Z34_09885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z34_09890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z34_09905	COG2226	methyltransferase
L2Z34_09925	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z34_09930	COG1074	ATP-dependent DNA helicase activity
L2Z34_09935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z34_09940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z34_09955	COG0598	Magnesium transport protein CorA
L2Z34_09960	COG0789	Transcriptional regulator
L2Z34_09965	COG0484	heat shock protein binding
L2Z34_09975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z34_09980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z34_09980	COG0475	glutathione-regulated potassium exporter activity
L2Z34_09985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z34_10005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z34_10015	COG4535	Mg2 and Co2 transporter CorC
L2Z34_10020	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z34_10025	COG0644	oxidoreductase
L2Z34_10025	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z34_10035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z34_10050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z34_10055	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z34_10095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z34_10110	COG0534	Mate efflux family protein
L2Z34_10120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z34_10125	COG4221	oxidoreductase activity
L2Z34_10130	COG0583	DNA-binding transcription factor activity
L2Z34_10145	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z34_10150	COG1530	ribonuclease E activity
L2Z34_10160	COG0546	phosphoglycolate phosphatase activity
L2Z34_10165	COG2378	regulation of single-species biofilm formation
L2Z34_10170	COG0625	glutathione transferase activity
L2Z34_10180	COG0583	DNA-binding transcription factor activity
L2Z34_10245	COG0473	3-isopropylmalate dehydrogenase activity
L2Z34_10300	COG1301	dicarboxylic acid transport
L2Z34_10310	COG1560	Kdo2-lipid A biosynthetic process
L2Z34_10315	COG1280	lysine exporter protein (LysE YggA)
L2Z34_10320	COG0488	(ABC) transporter
L2Z34_10325	COG2900	Belongs to the SlyX family
L2Z34_10335	COG1733	regulation of RNA biosynthetic process
L2Z34_10360	COG0210	DNA helicase
L2Z34_10365	COG0724	RNA recognition motif
L2Z34_10385	COG4651	solute:proton antiporter activity
L2Z34_10385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z34_10410	COG0788	formyltetrahydrofolate deformylase activity
L2Z34_10510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z34_10510	COG2813	Specifically methylates the guanine in position
L2Z34_10520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z34_10530	COG4774	siderophore transport
L2Z34_10540	COG0740	serine-type endopeptidase activity
L2Z34_10560	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z34_10560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z34_10565	COG0857	belongs to the CobB CobQ family
L2Z34_10565	COG0280	phosphate acetyltransferase
L2Z34_10570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z34_10585	COG0800	Aldolase
L2Z34_10595	COG3265	gluconokinase activity
L2Z34_10600	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_10610	COG2267	carboxylic ester hydrolase activity
L2Z34_10625	COG0793	Belongs to the peptidase S41A family
L2Z34_10660	COG1426	Protein conserved in bacteria
L2Z34_10705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z34_10715	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z34_10730	COG2986	histidine ammonia-lyase
L2Z34_10770	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_10775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z34_10795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z34_10805	COG1162	GTPase activity
L2Z34_10810	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z34_10825	COG1538	Outer membrane efflux protein
L2Z34_10830	COG0577	efflux transmembrane transporter activity
L2Z34_10830	COG1136	(ABC) transporter
L2Z34_10835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z34_10860	COG0028	Belongs to the TPP enzyme family
L2Z34_10865	COG0440	acetolactate synthase activity
L2Z34_10880	COG3676	manually curated
L2Z34_10900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z34_10915	COG0084	hydrolase, TatD family'
L2Z34_10930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z34_10940	COG0583	DNA-binding transcription factor activity
L2Z34_10950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z34_10955	COG2814	Major facilitator Superfamily
L2Z34_10965	COG0697	spore germination
L2Z34_10995	COG3622	Belongs to the hyi family
L2Z34_11000	COG2084	Dehydrogenase
L2Z34_11005	COG1024	Enoyl-CoA hydratase
L2Z34_11010	COG0784	Response regulator, receiver
L2Z34_11010	COG2205	protein histidine kinase activity
L2Z34_11010	COG5002	protein histidine kinase activity
L2Z34_11030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z34_11040	COG3956	TIGRFAM MazG family protein
L2Z34_11045	COG1555	photosystem II stabilization
L2Z34_11050	COG0617	tRNA 3'-terminal CCA addition
L2Z34_11055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z34_11075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z34_11080	COG3028	Belongs to the UPF0307 family
L2Z34_11085	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z34_11100	COG0625	glutathione transferase activity
L2Z34_11105	COG1238	metal cluster binding
L2Z34_11150	COG0072	phenylalanine-tRNA ligase activity
L2Z34_11180	COG0248	Ppx GppA phosphatase
L2Z34_11190	COG0037	tRNA processing
L2Z34_11240	COG1764	response to oxidative stress
L2Z34_11245	COG1846	Transcriptional regulator
L2Z34_11255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z34_11315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z34_11320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z34_11325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z34_11335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z34_11385	COG1214	PFAM Peptidase M22, glycoprotease
L2Z34_11410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z34_11415	COG0561	phosphatase activity
L2Z34_11425	COG2132	Multicopper oxidase
L2Z34_11430	COG3667	copper resistance
L2Z34_11445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z34_11450	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z34_11455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z34_11485	COG1063	alcohol dehydrogenase
L2Z34_11490	COG0583	DNA-binding transcription factor activity
L2Z34_11495	COG1960	acyl-CoA dehydrogenase activity
L2Z34_11500	COG2814	Major facilitator Superfamily
L2Z34_11505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z34_11515	COG1053	succinate dehydrogenase
L2Z34_11520	COG0583	DNA-binding transcription factor activity
L2Z34_11535	COG0583	DNA-binding transcription factor activity
L2Z34_11565	COG0583	DNA-binding transcription factor activity
L2Z34_11580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z34_11605	COG0384	phenazine biosynthesis protein PhzF
L2Z34_11625	COG4993	Dehydrogenase
L2Z34_11695	COG2205	protein histidine kinase activity
L2Z34_11705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z34_11725	COG0745	RESPONSE REGULATOR receiver
L2Z34_11765	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z34_11795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z34_11800	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z34_11820	COG0583	DNA-binding transcription factor activity
L2Z34_11840	COG0668	transmembrane transport
L2Z34_11850	COG2081	HI0933 family
L2Z34_11855	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z34_11885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z34_11885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z34_11895	COG0489	protein tyrosine kinase activity
L2Z34_11945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z34_11955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z34_11970	COG0730	response to heat
L2Z34_11980	COG1196	nuclear chromosome segregation
L2Z34_12000	COG2223	nitrite transmembrane transporter activity
L2Z34_12005	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z34_12010	COG1877	trehalose-phosphatase activity
L2Z34_12015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z34_12015	COG0596	Alpha beta hydrolase
L2Z34_12015	COG2226	methyltransferase
L2Z34_12030	COG4106	trans-aconitate 2-methyltransferase activity
L2Z34_12045	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z34_12050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z34_12055	COG0009	L-threonylcarbamoyladenylate synthase
L2Z34_12060	COG3101	peptidyl-lysine hydroxylation
L2Z34_12065	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z34_12090	COG1652	LysM domain
L2Z34_12095	COG0351	phosphomethylpyrimidine kinase
L2Z34_12095	COG0352	thiamine-phosphate diphosphorylase activity
L2Z34_12095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z34_12105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z34_12135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z34_12165	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z34_12180	COG0358	DNA primase activity
L2Z34_12190	COG0564	pseudouridine synthase activity
L2Z34_12215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z34_12235	COG0583	DNA-binding transcription factor activity
L2Z34_12240	COG0473	3-isopropylmalate dehydrogenase activity
L2Z34_12250	COG0657	acetylesterase activity
L2Z34_12260	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_12280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z34_12280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z34_12295	COG1981	membrane
L2Z34_12340	COG0456	acetyltransferase
L2Z34_12350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z34_12355	COG0492	ferredoxin-NADP+ reductase activity
L2Z34_12360	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z34_12360	COG1674	ftsk spoiiie
L2Z34_12365	COG1280	lysine exporter protein (LysE YggA)
L2Z34_12390	COG2894	cell division
L2Z34_12405	COG0204	Acyl-transferase
L2Z34_12410	COG2885	chlorophyll binding
L2Z34_12415	COG0210	DNA helicase
L2Z34_12425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z34_12440	COG0121	glutamine amidotransferase
L2Z34_12460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z34_12465	COG0735	belongs to the Fur family
L2Z34_12490	COG0420	3'-5' exonuclease activity
L2Z34_12510	COG1090	epimerase
L2Z34_12525	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z34_12535	COG2814	Major facilitator Superfamily
L2Z34_12540	COG0405	Gamma-glutamyltransferase
L2Z34_12610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z34_12700	COG1484	DNA-dependent DNA replication
L2Z34_12905	COG2026	Addiction module toxin, RelE StbE family
L2Z34_12945	COG0592	DNA-directed DNA polymerase activity
L2Z34_13070	COG0084	hydrolase, TatD family'
L2Z34_13090	COG0477	Major facilitator Superfamily
L2Z34_13095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z34_13110	COG1002	Type II restriction enzyme, methylase subunits
L2Z34_13115	COG1061	Type III restriction enzyme res subunit
L2Z34_13135	COG1595	DNA-templated transcription, initiation
L2Z34_13190	COG0531	amino acid
L2Z34_13195	COG2040	homocysteine
L2Z34_13220	COG1309	transcriptional regulator
L2Z34_13225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z34_13230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z34_13240	COG1607	acyl-coa hydrolase
L2Z34_13250	COG0523	cobalamin synthesis protein
L2Z34_13260	COG4681	YaeQ
L2Z34_13270	COG0726	polysaccharide deacetylase
L2Z34_13270	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z34_13275	COG1215	transferase activity, transferring glycosyl groups
L2Z34_13285	COG1024	Enoyl-CoA hydratase
L2Z34_13300	COG1414	Transcriptional regulator
L2Z34_13320	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_13330	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z34_13335	COG2271	Major facilitator Superfamily
L2Z34_13345	COG2267	carboxylic ester hydrolase activity
L2Z34_13350	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_13365	COG0028	Belongs to the TPP enzyme family
L2Z34_13375	COG0477	Major facilitator Superfamily
L2Z34_13380	COG0242	peptide deformylase activity
L2Z34_13385	COG2066	Belongs to the glutaminase family
L2Z34_13390	COG2207	Transcriptional regulator
L2Z34_13395	COG2223	nitrite transmembrane transporter activity
L2Z34_13410	COG0583	DNA-binding transcription factor activity
L2Z34_13415	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_13420	COG2271	Major facilitator Superfamily
L2Z34_13425	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z34_13430	COG3958	Transketolase
L2Z34_13440	COG0306	phosphate transporter
L2Z34_13460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z34_13505	COG4181	ATPase activity
L2Z34_13510	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z34_13535	COG0583	DNA-binding transcription factor activity
L2Z34_13545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z34_13550	COG1773	rubredoxin
L2Z34_13605	COG2851	Citrate transporter
L2Z34_13610	COG1253	flavin adenine dinucleotide binding
L2Z34_13650	COG0804	urea catabolic process
L2Z34_13660	COG0830	nickel cation binding
L2Z34_13675	COG0742	ribosomal rna small subunit methyltransferase
L2Z34_13680	COG0768	penicillin binding
L2Z34_13705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z34_13710	COG2878	Part of a membrane complex involved in electron transport
L2Z34_13715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z34_13725	COG3384	dioxygenase
L2Z34_13755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z34_14080	COG0739	heme binding
L2Z34_14170	COG0006	proline dipeptidase activity
L2Z34_14175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z34_14180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z34_14200	COG1279	arginine transmembrane transporter activity
L2Z34_14205	COG0583	DNA-binding transcription factor activity
L2Z34_14245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z34_14250	COG0741	lytic transglycosylase activity
L2Z34_14250	COG1388	LysM domain
L2Z34_14250	COG1388	LysM domain
L2Z34_14250	COG0741	lytic transglycosylase activity
L2Z34_14260	COG4174	ABC transporter (Permease)
L2Z34_14270	COG4172	Belongs to the ABC transporter superfamily
L2Z34_14295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z34_14305	COG2203	Gaf domain
L2Z34_14305	COG4251	negative regulation of phosphorylation
L2Z34_14305	COG5001	Diguanylate cyclase
L2Z34_14305	COG3706	GGDEF domain
L2Z34_14315	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z34_14315	COG1902	pentaerythritol trinitrate reductase activity
L2Z34_14355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2Z34_14385	COG1741	Belongs to the pirin family
L2Z34_14400	COG2072	flavoprotein involved in K transport
L2Z34_14410	COG2252	PERMEase
L2Z34_14415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z34_14420	COG3038	cytochrome b561
L2Z34_14430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z34_14440	COG0527	aspartate kinase activity
L2Z34_14450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z34_14460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z34_14475	COG0667	Aldo Keto reductase
L2Z34_14495	COG1765	OsmC-like protein
L2Z34_14510	COG0542	response to heat
L2Z34_14545	COG2885	chlorophyll binding
L2Z34_14555	COG0625	glutathione transferase activity
L2Z34_14560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z34_14580	COG3634	alkyl hydroperoxide reductase activity
L2Z34_14590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z34_14600	COG0450	alkyl hydroperoxide reductase
L2Z34_14605	COG1643	Atp-dependent helicase
L2Z34_14620	COG2814	Major facilitator Superfamily
L2Z34_14625	COG3135	benzoate transporter
L2Z34_14630	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_14635	COG0543	2 iron, 2 sulfur cluster binding
L2Z34_14635	COG0633	Ferredoxin
L2Z34_14640	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z34_14645	COG4638	Rieske (2fe-2S)
L2Z34_14655	COG0583	DNA-binding transcription factor activity
L2Z34_14705	COG1570	exodeoxyribonuclease VII activity
L2Z34_14745	COG1278	Cold shock
L2Z34_14780	COG2814	Major facilitator Superfamily
L2Z34_14815	COG0517	IMP dehydrogenase activity
L2Z34_14815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z34_14820	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z34_14830	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z34_14835	COG1137	ATPase activity
L2Z34_14840	COG1538	Outer membrane efflux protein
L2Z34_14870	COG4122	O-methyltransferase activity
L2Z34_14880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z34_14895	COG1522	sequence-specific DNA binding
L2Z34_14900	COG5006	permease, DMT superfamily
L2Z34_14910	COG1560	Kdo2-lipid A biosynthetic process
L2Z34_14925	COG2814	Major facilitator Superfamily
L2Z34_14945	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z34_14995	COG0583	DNA-binding transcription factor activity
L2Z34_15000	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z34_15020	COG4770	biotin carboxylase activity
L2Z34_15025	COG0038	chloride channel
L2Z34_15045	COG1309	transcriptional regulator
L2Z34_15055	COG1063	alcohol dehydrogenase
L2Z34_15070	COG0439	Biotin carboxylase
L2Z34_15075	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z34_15095	COG0864	Transcriptional regulator
L2Z34_15105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z34_15110	COG1116	anion transmembrane transporter activity
L2Z34_15235	COG0590	tRNA wobble adenosine to inosine editing
L2Z34_15240	COG2807	transmembrane transport
L2Z34_15255	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z34_15270	COG0789	Transcriptional regulator
L2Z34_15280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z34_15300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z34_15310	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z34_15325	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_15330	COG0531	amino acid
L2Z34_15335	COG1760	l-serine dehydratase
L2Z34_15340	COG2030	dehydratase
L2Z34_15340	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_15345	COG3396	Phenylacetate-CoA oxygenase
L2Z34_15350	COG3460	Phenylacetate-CoA oxygenase
L2Z34_15355	COG3396	Phenylacetate-CoA oxygenase
L2Z34_15360	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z34_15365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z34_15370	COG1024	Enoyl-CoA hydratase
L2Z34_15375	COG1024	Enoyl-CoA hydratase
L2Z34_15380	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z34_15385	COG0183	Belongs to the thiolase family
L2Z34_15390	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z34_15395	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z34_15405	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z34_15435	COG0753	catalase activity
L2Z34_15440	COG3038	cytochrome b561
L2Z34_15460	COG2267	carboxylic ester hydrolase activity
L2Z34_15465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z34_15470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z34_15475	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_15485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z34_15495	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_15500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z34_15505	COG0583	DNA-binding transcription factor activity
L2Z34_15515	COG1414	Transcriptional regulator
L2Z34_15520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z34_15530	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z34_15535	COG3842	ATPase activity
L2Z34_15550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z34_15555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z34_15560	COG2814	Major facilitator Superfamily
L2Z34_15565	COG1960	acyl-CoA dehydrogenase activity
L2Z34_15580	COG1024	Enoyl-CoA hydratase
L2Z34_15590	COG2814	Major facilitator Superfamily
L2Z34_15600	COG0183	Belongs to the thiolase family
L2Z34_15605	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z34_15610	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_15615	COG1024	Enoyl-CoA hydratase
L2Z34_15620	COG1960	acyl-CoA dehydrogenase activity
L2Z34_15625	COG2814	Major facilitator Superfamily
L2Z34_15630	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z34_15635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z34_15645	COG2814	Major facilitator Superfamily
L2Z34_15655	COG1960	acyl-CoA dehydrogenase activity
L2Z34_15670	COG0583	DNA-binding transcription factor activity
L2Z34_15680	COG4770	biotin carboxylase activity
L2Z34_15685	COG1024	Enoyl-CoA hydratase
L2Z34_15690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z34_15695	COG1960	acyl-CoA dehydrogenase activity
L2Z34_15700	COG1309	transcriptional regulator
L2Z34_15705	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z34_15725	COG0583	DNA-binding transcription factor activity
L2Z34_15775	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_15795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z34_15815	COG2205	protein histidine kinase activity
L2Z34_15815	COG0784	Response regulator, receiver
L2Z34_15835	COG0765	amino acid transport
L2Z34_15840	COG0765	amino acid transport
L2Z34_15845	COG1126	abc transporter atp-binding protein
L2Z34_15850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z34_15855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z34_15870	COG1280	lysine exporter protein (LysE YggA)
L2Z34_15880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z34_15885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z34_15890	COG1045	serine acetyltransferase
L2Z34_15905	COG0583	DNA-binding transcription factor activity
L2Z34_15910	COG0625	glutathione transferase activity
L2Z34_15915	COG0625	glutathione transferase activity
L2Z34_15920	COG0583	DNA-binding transcription factor activity
L2Z34_15930	COG1346	cytolysis
L2Z34_15950	COG2814	Major facilitator Superfamily
L2Z34_15960	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z34_15965	COG3052	prosthetic group binding
L2Z34_15985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z34_16005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z34_16015	COG1294	oxidase, subunit
L2Z34_16020	COG1271	oxidase subunit
L2Z34_16040	COG0477	Major facilitator Superfamily
L2Z34_16050	COG4521	taurine ABC transporter
L2Z34_16055	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z34_16060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z34_16065	COG2175	clavaminate synthase activity
L2Z34_16075	COG1953	Uracil, thiamine, allantoin
L2Z34_16085	COG0583	DNA-binding transcription factor activity
L2Z34_16095	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z34_16110	COG0640	Transcriptional regulator
L2Z34_16115	COG0798	PFAM Bile acid sodium symporter
L2Z34_16120	COG0583	DNA-binding transcription factor activity
L2Z34_16135	COG3634	alkyl hydroperoxide reductase activity
L2Z34_16175	COG0436	Aminotransferase
L2Z34_16185	COG0386	Belongs to the glutathione peroxidase family
L2Z34_16225	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z34_16250	COG0012	GTP binding
L2Z34_16255	COG2011	ABC-type metal ion transport system permease component
L2Z34_16260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z34_16270	COG1464	Belongs to the NlpA lipoprotein family
L2Z34_16300	COG0765	amino acid transport
L2Z34_16305	COG0765	amino acid transport
L2Z34_16310	COG1126	abc transporter atp-binding protein
L2Z34_16320	COG1522	sequence-specific DNA binding
L2Z34_16335	COG1309	transcriptional regulator
L2Z34_16355	COG0583	DNA-binding transcription factor activity
L2Z34_16365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z34_16375	COG0697	spore germination
L2Z34_16400	COG3121	Chaperone
L2Z34_16430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z34_16430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z34_16475	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z34_16485	COG2353	YceI-like domain
L2Z34_16510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z34_16515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z34_16515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z34_16515	COG0506	proline dehydrogenase activity
L2Z34_16525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z34_16530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z34_16550	COG1132	(ABC) transporter
L2Z34_16555	COG3122	Protein conserved in bacteria
L2Z34_16560	COG3619	membrane
L2Z34_16575	COG0640	Transcriptional regulator
L2Z34_16585	COG2850	peptidyl-arginine hydroxylation
L2Z34_16590	COG0424	maF-like protein
L2Z34_16610	COG0191	fructose-bisphosphate aldolase activity
L2Z34_16615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z34_16630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z34_16640	COG1192	Involved in chromosome partitioning
L2Z34_16645	COG1475	DNA binding
L2Z34_16650	COG0811	peptide transport
L2Z34_16660	COG1132	(ABC) transporter
L2Z34_16665	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z34_16685	COG0084	hydrolase, TatD family'
L2Z34_16750	COG0776	regulation of translation
L2Z34_16780	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z34_16785	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z34_16835	COG0339	signal peptide processing
L2Z34_16845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z34_16880	COG0702	epimerase
L2Z34_16885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z34_16905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z34_16935	COG0316	Belongs to the HesB IscA family
L2Z34_16940	COG0822	iron-sulfur transferase activity
L2Z34_16965	COG0776	regulation of translation
L2Z34_16970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z34_16975	COG2207	Transcriptional regulator
L2Z34_16980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z34_16985	COG1960	acyl-CoA dehydrogenase activity
L2Z34_16990	COG1960	acyl-CoA dehydrogenase activity
L2Z34_17005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z34_17025	COG4264	IucA IucC family
L2Z34_17030	COG4264	IucA IucC family
L2Z34_17070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z34_17085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z34_17105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z34_17110	COG0730	response to heat
L2Z34_17135	COG3676	manually curated
L2Z34_17145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z34_17160	COG1131	(ABC) transporter
L2Z34_17165	COG0842	Transport permease protein
L2Z34_17170	COG0842	Transport permease protein
L2Z34_17225	COG2226	methyltransferase
L2Z34_17250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z34_17285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z34_17295	COG0133	tryptophan synthase activity
L2Z34_17310	COG3706	GGDEF domain
L2Z34_17325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z34_17330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z34_17335	COG0022	dehydrogenase e1 component
L2Z34_17340	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z34_17345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z34_17355	COG1063	alcohol dehydrogenase
L2Z34_17360	COG3781	membrane
L2Z34_17370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z34_17370	COG3453	Protein conserved in bacteria
L2Z34_17385	COG0730	response to heat
L2Z34_17400	COG2207	Transcriptional regulator
L2Z34_17400	COG3708	Transcriptional regulator
L2Z34_17405	COG1733	regulation of RNA biosynthetic process
L2Z34_17410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z34_17420	COG2188	Transcriptional regulator
L2Z34_17435	COG4521	taurine ABC transporter
L2Z34_17440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z34_17460	COG0477	Major facilitator Superfamily
L2Z34_17470	COG1027	Aspartate ammonia-lyase
L2Z34_17485	COG0583	DNA-binding transcription factor activity
L2Z34_17490	COG0583	DNA-binding transcription factor activity
L2Z34_17495	COG0183	Belongs to the thiolase family
L2Z34_17500	COG2031	fatty acid transporter
L2Z34_17505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z34_17515	COG0583	DNA-binding transcription factor activity
L2Z34_17525	COG2610	gluconate transmembrane transporter activity
L2Z34_17530	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_17540	COG2207	Transcriptional regulator
L2Z34_17555	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_17580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z34_17580	COG0543	2 iron, 2 sulfur cluster binding
L2Z34_17585	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z34_17590	COG4638	Rieske (2fe-2S)
L2Z34_17600	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z34_17605	COG4149	molybdate abc transporter
L2Z34_17610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z34_17615	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_17620	COG3433	isochorismatase activity
L2Z34_17620	COG1535	isochorismatase
L2Z34_17635	COG3539	Fimbrial protein
L2Z34_17655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z34_17675	COG2072	flavoprotein involved in K transport
L2Z34_17685	COG1538	Outer membrane efflux protein
L2Z34_17690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z34_17695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z34_17700	COG0745	RESPONSE REGULATOR receiver
L2Z34_17705	COG2205	protein histidine kinase activity
L2Z34_17715	COG2207	Transcriptional regulator
L2Z34_17730	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_17780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z34_17900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z34_17920	COG1120	ATPase activity
L2Z34_17925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z34_17935	COG1064	alcohol dehydrogenase
L2Z34_17950	COG2207	Transcriptional regulator
L2Z34_17955	COG2084	Dehydrogenase
L2Z34_17965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z34_17970	COG0583	DNA-binding transcription factor activity
L2Z34_17980	COG0129	dihydroxy-acid dehydratase activity
L2Z34_17985	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_18000	COG1566	PFAM secretion protein HlyD family protein
L2Z34_18020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z34_18050	COG0583	DNA-binding transcription factor activity
L2Z34_18065	COG2188	Transcriptional regulator
L2Z34_18095	COG3210	domain, Protein
L2Z34_18100	COG2831	hemolysin activation secretion protein
L2Z34_18110	COG1473	amidohydrolase
L2Z34_18120	COG0475	glutathione-regulated potassium exporter activity
L2Z34_18120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z34_18130	COG0583	DNA-binding transcription factor activity
L2Z34_18135	COG1335	isochorismatase
L2Z34_18145	COG1309	transcriptional regulator
L2Z34_18175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z34_18185	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z34_18185	COG1902	pentaerythritol trinitrate reductase activity
L2Z34_18190	COG1846	Transcriptional regulator
L2Z34_18210	COG0753	catalase activity
L2Z34_18225	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_18240	COG3162	membrane
L2Z34_18255	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_18260	COG1960	acyl-CoA dehydrogenase activity
L2Z34_18280	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_18300	COG2186	Transcriptional regulator
L2Z34_18310	COG0583	DNA-binding transcription factor activity
L2Z34_18315	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z34_18320	COG4829	muconolactone delta-isomerase
L2Z34_18330	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z34_18335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z34_18340	COG0183	Belongs to the thiolase family
L2Z34_18345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z34_18355	COG1012	belongs to the aldehyde dehydrogenase family
L2Z34_18365	COG3733	amine oxidase
L2Z34_18375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z34_18385	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z34_18395	COG4638	Rieske (2fe-2S)
L2Z34_18415	COG0154	amidase activity
L2Z34_18425	COG2814	Major facilitator Superfamily
L2Z34_18450	COG1960	acyl-CoA dehydrogenase activity
L2Z34_18455	COG0583	DNA-binding transcription factor activity
L2Z34_18460	COG1414	Transcriptional regulator
L2Z34_18475	COG2391	methyltransferase activity
L2Z34_18485	COG4993	Dehydrogenase
L2Z34_18490	COG3659	wide pore channel activity
L2Z34_18495	COG3420	alginic acid biosynthetic process
L2Z34_18500	COG0710	3-dehydroquinate dehydratase activity
L2Z34_18505	COG3485	protocatechuate 3,4-dioxygenase
L2Z34_18510	COG3485	protocatechuate 3,4-dioxygenase
L2Z34_18515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z34_18520	COG2271	Major facilitator Superfamily
L2Z34_18525	COG0596	Alpha beta hydrolase
L2Z34_18530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z34_18535	COG0183	Belongs to the thiolase family
L2Z34_18540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z34_18545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z34_18555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z34_18560	COG2323	membrane
L2Z34_18605	COG1902	pentaerythritol trinitrate reductase activity
L2Z34_18605	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z34_18630	COG0542	response to heat
L2Z34_18635	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z34_18665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z34_18670	COG0569	domain protein
L2Z34_18675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z34_18690	COG4774	siderophore transport
L2Z34_18695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z34_18705	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z34_18720	COG1294	oxidase, subunit
L2Z34_18725	COG4890	Cyd operon protein YbgT
L2Z34_18740	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z34_18750	COG0552	protein localization to endoplasmic reticulum
L2Z34_18775	COG0516	GMP reductase activity
L2Z34_18775	COG0517	IMP dehydrogenase activity
L2Z34_18780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z34_18785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z34_18795	COG0583	DNA-binding transcription factor activity
L2Z34_18800	COG0024	Methionine aminopeptidase
L2Z34_18830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z34_18830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z34_18835	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z34_18840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z34_18840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z34_18840	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z34_18860	COG3300	MHYT domain
L2Z34_18860	COG5001	Diguanylate cyclase
L2Z34_18875	COG2135	peptidase activity
L2Z34_18880	COG0659	secondary active sulfate transmembrane transporter activity
L2Z34_18900	COG1113	amino acid transport
L2Z34_18910	COG1522	sequence-specific DNA binding
L2Z34_18935	COG1011	Hydrolase
L2Z34_18940	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z34_18950	COG2137	regulation of response to DNA damage stimulus
L2Z34_18965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z34_19000	COG0575	Belongs to the CDS family
L2Z34_19005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z34_19025	COG3852	Histidine kinase
L2Z34_19030	COG2204	response regulator
L2Z34_19085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z34_19090	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z34_19110	COG0697	spore germination
L2Z34_19115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z34_19125	COG0303	'Molybdopterin
L2Z34_19130	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z34_19130	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z34_19145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z34_19150	COG0243	molybdopterin cofactor binding
L2Z34_19160	COG0243	molybdopterin cofactor binding
L2Z34_19165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z34_19170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z34_19170	COG2146	nitrite reductase [NAD(P)H] activity
L2Z34_19180	COG0745	RESPONSE REGULATOR receiver
L2Z34_19185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z34_19185	COG1116	anion transmembrane transporter activity
L2Z34_19205	COG0511	ligase activity, forming carbon-carbon bonds
L2Z34_19220	COG2814	Major facilitator Superfamily
L2Z34_19285	COG0739	heme binding