locus-tag	class	description
L2Z36_00040	COG0733	neurotransmitter:sodium symporter activity
L2Z36_00075	COG0583	DNA-binding transcription factor activity
L2Z36_00080	COG2233	PERMEase
L2Z36_00095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z36_00130	COG2814	Major facilitator Superfamily
L2Z36_00135	COG0656	L-ascorbic acid biosynthetic process
L2Z36_00140	COG0583	DNA-binding transcription factor activity
L2Z36_00155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z36_00160	COG1064	alcohol dehydrogenase
L2Z36_00165	COG2818	Glycosylase
L2Z36_00180	COG1194	a g-specific adenine glycosylase
L2Z36_00200	COG2983	Belongs to the UPF0260 family
L2Z36_00205	COG2133	pyrroloquinoline quinone binding
L2Z36_00210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z36_00215	COG2116	formate transmembrane transporter activity
L2Z36_00235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z36_00240	COG1335	isochorismatase
L2Z36_00245	COG0385	Bile acid
L2Z36_00250	COG0534	Mate efflux family protein
L2Z36_00255	COG1683	Conserved Protein
L2Z36_00275	COG0625	glutathione transferase activity
L2Z36_00285	COG1113	amino acid transport
L2Z36_00295	COG0523	cobalamin synthesis protein
L2Z36_00305	COG2188	Transcriptional regulator
L2Z36_00335	COG0010	Belongs to the arginase family
L2Z36_00350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z36_00380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z36_00390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z36_00395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z36_00480	COG0534	Mate efflux family protein
L2Z36_00485	COG0436	Aminotransferase
L2Z36_00490	COG2733	membrane
L2Z36_00505	COG2918	glutathione biosynthetic process
L2Z36_00560	COG3150	esterase
L2Z36_00570	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z36_00580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z36_00590	COG2233	PERMEase
L2Z36_00595	COG2351	hydroxyisourate hydrolase activity
L2Z36_00630	COG3706	GGDEF domain
L2Z36_00645	COG1393	Belongs to the ArsC family
L2Z36_00650	COG0708	Exodeoxyribonuclease III
L2Z36_00670	COG0189	ligase activity
L2Z36_00690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z36_00700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z36_00715	COG4942	peptidase
L2Z36_00725	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z36_00735	COG2119	membrane
L2Z36_00740	COG4774	siderophore transport
L2Z36_00745	COG0426	domain, Protein
L2Z36_00745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z36_00770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z36_00790	COG1902	pentaerythritol trinitrate reductase activity
L2Z36_00795	COG1519	Transferase
L2Z36_00800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z36_00805	COG0668	transmembrane transport
L2Z36_00815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z36_00820	COG1335	isochorismatase
L2Z36_00825	COG1522	sequence-specific DNA binding
L2Z36_00850	COG0784	Response regulator, receiver
L2Z36_00850	COG2205	protein histidine kinase activity
L2Z36_00850	COG2198	Histidine kinase
L2Z36_00855	COG3162	membrane
L2Z36_00860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z36_00870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z36_00885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z36_00890	COG1309	transcriptional regulator
L2Z36_00910	COG0351	phosphomethylpyrimidine kinase
L2Z36_00910	COG0352	thiamine-phosphate diphosphorylase activity
L2Z36_00910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z36_00920	COG2814	Major facilitator Superfamily
L2Z36_00935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z36_00945	COG1113	amino acid transport
L2Z36_00955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z36_00960	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_00970	COG1335	isochorismatase
L2Z36_01000	COG2814	Major facilitator Superfamily
L2Z36_01005	COG0583	DNA-binding transcription factor activity
L2Z36_01025	COG0667	Aldo Keto reductase
L2Z36_01045	COG1733	regulation of RNA biosynthetic process
L2Z36_01060	COG1733	regulation of RNA biosynthetic process
L2Z36_01065	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z36_01075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2Z36_01135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z36_01175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z36_01205	COG0427	acetyl-CoA hydrolase
L2Z36_01235	COG0659	secondary active sulfate transmembrane transporter activity
L2Z36_01240	COG4221	oxidoreductase activity
L2Z36_01245	COG2873	o-acetylhomoserine
L2Z36_01250	COG0488	(ABC) transporter
L2Z36_01315	COG0833	amino acid
L2Z36_01360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z36_01365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z36_01380	COG2226	methyltransferase
L2Z36_01430	COG0069	glutamate synthase activity
L2Z36_01430	COG0067	glutamate synthase
L2Z36_01430	COG0070	glutamate synthase
L2Z36_01435	COG0493	'glutamate synthase
L2Z36_01445	COG1704	LemA family
L2Z36_01450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z36_01465	COG3307	-O-antigen
L2Z36_01485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z36_01500	COG0194	GDP metabolic process
L2Z36_01550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z36_01570	COG5380	lipid catabolic process
L2Z36_01575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z36_01600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z36_01605	COG0277	FAD linked oxidase domain protein
L2Z36_01615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z36_01620	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z36_01635	COG1289	transmembrane transporter activity
L2Z36_01645	COG0628	permease
L2Z36_01650	COG1192	Involved in chromosome partitioning
L2Z36_01680	COG0833	amino acid
L2Z36_01685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z36_01690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z36_01700	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_01740	COG0583	DNA-binding transcription factor activity
L2Z36_01790	COG0517	IMP dehydrogenase activity
L2Z36_01795	COG1983	PspC domain protein
L2Z36_01805	COG1960	acyl-CoA dehydrogenase activity
L2Z36_01820	COG0408	coproporphyrinogen oxidase activity
L2Z36_01840	COG0513	Belongs to the DEAD box helicase family
L2Z36_01850	COG1127	ABC transporter
L2Z36_01855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z36_01865	COG2854	intermembrane phospholipid transfer
L2Z36_01875	COG0598	Magnesium transport protein CorA
L2Z36_01885	COG0494	nUDIX hydrolase
L2Z36_01890	COG1040	competence protein
L2Z36_01895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z36_01915	COG1946	Acyl-CoA thioesterase
L2Z36_01920	COG1301	dicarboxylic acid transport
L2Z36_01935	COG1959	2 iron, 2 sulfur cluster binding
L2Z36_01940	COG1017	nitric oxide dioxygenase activity
L2Z36_01940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z36_01945	COG0433	COG0433 Predicted ATPase
L2Z36_01950	COG0626	cystathionine gamma-synthase activity
L2Z36_02105	COG1960	acyl-CoA dehydrogenase activity
L2Z36_02110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z36_02140	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z36_02145	COG0339	signal peptide processing
L2Z36_02150	COG0557	exoribonuclease II activity
L2Z36_02195	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z36_02200	COG2169	Transcriptional regulator
L2Z36_02205	COG0697	spore germination
L2Z36_02210	COG1295	ribonuclease BN
L2Z36_02245	COG1702	phosphate starvation-inducible protein PhoH
L2Z36_02255	COG0741	lytic transglycosylase activity
L2Z36_02255	COG1196	nuclear chromosome segregation
L2Z36_02255	COG0739	heme binding
L2Z36_02285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z36_02290	COG1183	phosphatidylcholine synthase activity
L2Z36_02335	COG1960	acyl-CoA dehydrogenase activity
L2Z36_02340	COG1309	transcriptional regulator
L2Z36_02355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z36_02360	COG1960	acyl-CoA dehydrogenase activity
L2Z36_02380	COG2969	positive regulation of protein catabolic process
L2Z36_02390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z36_02405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z36_02410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z36_02430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z36_02440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z36_02445	COG1408	metallophosphoesterase
L2Z36_02455	COG2199	diguanylate cyclase activity
L2Z36_02515	COG1607	acyl-coa hydrolase
L2Z36_02545	COG2350	Protein conserved in bacteria
L2Z36_02555	COG0613	PHP domain protein
L2Z36_02560	COG3781	membrane
L2Z36_02570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z36_02585	COG1862	Preprotein translocase
L2Z36_02630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z36_02635	COG0629	single-stranded DNA binding
L2Z36_02680	COG3646	Phage regulatory protein
L2Z36_02690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L2Z36_02820	COG4695	Portal protein
L2Z36_02825	COG2205	protein histidine kinase activity
L2Z36_02830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z36_02850	COG0726	polysaccharide deacetylase
L2Z36_02855	COG0463	Glycosyl transferase, family 2
L2Z36_02860	COG0438	transferase activity, transferring glycosyl groups
L2Z36_02935	COG1960	acyl-CoA dehydrogenase activity
L2Z36_02940	COG1960	acyl-CoA dehydrogenase activity
L2Z36_02950	COG2205	protein histidine kinase activity
L2Z36_02955	COG0745	RESPONSE REGULATOR receiver
L2Z36_02960	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z36_02980	COG2096	Adenosyltransferase
L2Z36_03030	COG0285	dihydrofolate synthase activity
L2Z36_03050	COG0450	alkyl hydroperoxide reductase
L2Z36_03065	COG0477	Major facilitator Superfamily
L2Z36_03070	COG1272	protein, Hemolysin III
L2Z36_03080	COG2153	protein acetylation
L2Z36_03100	COG0183	Belongs to the thiolase family
L2Z36_03105	COG2207	Transcriptional regulator
L2Z36_03125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z36_03145	COG0183	Belongs to the thiolase family
L2Z36_03155	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z36_03155	COG2885	chlorophyll binding
L2Z36_03165	COG1690	Belongs to the RtcB family
L2Z36_03170	COG0833	amino acid
L2Z36_03180	COG2233	PERMEase
L2Z36_03185	COG1217	gtp-binding protein TYPA
L2Z36_03210	COG2094	Belongs to the DNA glycosylase MPG family
L2Z36_03215	COG4772	TonB-dependent receptor
L2Z36_03220	COG1902	pentaerythritol trinitrate reductase activity
L2Z36_03235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z36_03240	COG0354	folic acid binding
L2Z36_03250	COG3189	MarR family transcriptional regulator
L2Z36_03255	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z36_03260	COG3422	double-strand break repair
L2Z36_03300	COG0840	transmembrane signaling receptor activity
L2Z36_03315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z36_03330	COG5510	response to toxic substance
L2Z36_03340	COG2832	Protein of unknown function (DUF454)
L2Z36_03345	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z36_03385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z36_03395	COG1289	transmembrane transporter activity
L2Z36_03400	COG2814	Major facilitator Superfamily
L2Z36_03420	COG1115	amino acid carrier protein
L2Z36_03425	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z36_03430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z36_03435	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z36_03460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z36_03470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z36_03475	COG1077	Cell shape determining protein MreB Mrl
L2Z36_03480	COG1792	Involved in formation and maintenance of cell shape
L2Z36_03485	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z36_03490	COG0424	maF-like protein
L2Z36_03495	COG1530	ribonuclease E activity
L2Z36_03505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z36_03515	COG0560	Phosphoserine phosphatase
L2Z36_03525	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z36_03550	COG2207	Transcriptional regulator
L2Z36_03570	COG1113	amino acid transport
L2Z36_03575	COG2828	Protein conserved in bacteria
L2Z36_03580	COG0142	geranyltranstransferase activity
L2Z36_03585	COG2315	Protein conserved in bacteria
L2Z36_03600	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z36_03615	COG3676	manually curated
L2Z36_03630	COG2194	sulfuric ester hydrolase activity
L2Z36_03635	COG0745	RESPONSE REGULATOR receiver
L2Z36_03640	COG0642	Histidine kinase
L2Z36_03650	COG0004	ammonium transporteR
L2Z36_03655	COG0583	DNA-binding transcription factor activity
L2Z36_03675	COG0525	valine-tRNA ligase activity
L2Z36_03685	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_03695	COG0393	Putative heavy-metal-binding
L2Z36_03700	COG0393	Putative heavy-metal-binding
L2Z36_03705	COG1538	Outer membrane efflux protein
L2Z36_03715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z36_03720	COG0671	phosphoesterase, PA-phosphatase related
L2Z36_03725	COG3676	manually curated
L2Z36_03755	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z36_03770	COG1648	precorrin-2 dehydrogenase activity
L2Z36_03770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z36_03775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z36_03780	COG1733	regulation of RNA biosynthetic process
L2Z36_03790	COG0531	amino acid
L2Z36_03805	COG0321	lipoyl(octanoyl) transferase activity
L2Z36_03810	COG2921	Belongs to the UPF0250 family
L2Z36_03845	COG2009	succinate dehydrogenase
L2Z36_03850	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z36_03855	COG1053	succinate dehydrogenase
L2Z36_03860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z36_03885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z36_03915	COG2354	Protein conserved in bacteria
L2Z36_03920	COG2321	neutral zinc metallopeptidase
L2Z36_03950	COG2843	Capsule synthesis protein
L2Z36_03965	COG0589	response to stress
L2Z36_03985	COG0505	Belongs to the CarA family
L2Z36_04010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z36_04015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z36_04065	COG0477	Major facilitator Superfamily
L2Z36_04070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z36_04085	COG1597	lipid kinase activity
L2Z36_04090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z36_04115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z36_04120	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z36_04140	COG0741	lytic transglycosylase activity
L2Z36_04160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z36_04175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z36_04210	COG0778	Nitroreductase
L2Z36_04225	COG1929	Belongs to the glycerate kinase type-1 family
L2Z36_04230	COG0243	molybdopterin cofactor binding
L2Z36_04235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z36_04240	COG3339	Conserved Protein
L2Z36_04250	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z36_04265	COG1113	amino acid transport
L2Z36_04275	COG0019	diaminopimelate decarboxylase activity
L2Z36_04285	COG1280	lysine exporter protein (LysE YggA)
L2Z36_04290	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z36_04320	COG0463	Glycosyl transferase, family 2
L2Z36_04340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z36_04375	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z36_04380	COG1136	(ABC) transporter
L2Z36_04385	COG0658	competence protein
L2Z36_04385	COG2333	competence protein COMEC
L2Z36_04395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z36_04395	COG0616	signal peptide processing
L2Z36_04400	COG0596	Alpha beta hydrolase
L2Z36_04405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z36_04415	COG0628	permease
L2Z36_04450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z36_04470	COG0823	Involved in the tonB-independent uptake of proteins
L2Z36_04490	COG0824	Thioesterase
L2Z36_04495	COG1473	amidohydrolase
L2Z36_04515	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z36_04515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z36_04520	COG2814	Major facilitator Superfamily
L2Z36_04530	COG1024	Enoyl-CoA hydratase
L2Z36_04535	COG1051	belongs to the nudix hydrolase family
L2Z36_04535	COG1056	cytidyltransferase-related domain
L2Z36_04545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z36_04560	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z36_04575	COG4625	pathogenesis
L2Z36_04580	COG0583	DNA-binding transcription factor activity
L2Z36_04585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z36_04590	COG4208	sulfate ABC transporter
L2Z36_04595	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z36_04605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z36_04610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z36_04615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z36_04635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z36_04650	COG0681	Belongs to the peptidase S26 family
L2Z36_04665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z36_04675	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z36_04680	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z36_04690	COG4221	oxidoreductase activity
L2Z36_04720	COG0436	Aminotransferase
L2Z36_04745	COG0556	nucleotide-excision repair
L2Z36_04800	COG2070	2-Nitropropane dioxygenase
L2Z36_04830	COG1215	transferase activity, transferring glycosyl groups
L2Z36_04845	COG0415	Belongs to the DNA photolyase family
L2Z36_04855	COG1252	NADH dehydrogenase
L2Z36_04860	COG1686	Belongs to the peptidase S11 family
L2Z36_04875	COG1187	pseudouridine synthase activity
L2Z36_04895	COG0477	Major facilitator Superfamily
L2Z36_04900	COG0583	DNA-binding transcription factor activity
L2Z36_04905	COG1823	symporter activity
L2Z36_04915	COG0612	Peptidase, M16
L2Z36_04945	COG1203	CRISPR-associated helicase, Cas3
L2Z36_04970	COG0352	thiamine-phosphate diphosphorylase activity
L2Z36_05005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z36_05020	COG1309	transcriptional regulator
L2Z36_05030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z36_05035	COG0076	glutamate decarboxylase activity
L2Z36_05045	COG1522	sequence-specific DNA binding
L2Z36_05050	COG3961	Belongs to the TPP enzyme family
L2Z36_05055	COG1113	amino acid transport
L2Z36_05060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z36_05065	COG0573	inorganic phosphate transmembrane transporter activity
L2Z36_05075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z36_05080	COG0616	signal peptide processing
L2Z36_05115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z36_05120	COG1686	Belongs to the peptidase S11 family
L2Z36_05145	COG0583	DNA-binding transcription factor activity
L2Z36_05150	COG1067	ATP-dependent peptidase activity
L2Z36_05175	COG4943	cyclic-guanylate-specific phosphodiesterase activity
L2Z36_05195	COG1966	Carbon starvation protein
L2Z36_05200	COG2879	small protein
L2Z36_05210	COG0583	DNA-binding transcription factor activity
L2Z36_05215	COG0006	proline dipeptidase activity
L2Z36_05220	COG0006	proline dipeptidase activity
L2Z36_05225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z36_05230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z36_05240	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_05250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z36_05255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z36_05255	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z36_05315	COG1741	Belongs to the pirin family
L2Z36_05325	COG2964	Protein conserved in bacteria
L2Z36_05340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z36_05345	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z36_05350	COG4605	iron ion homeostasis
L2Z36_05355	COG4604	ABC transporter, ATP-binding protein
L2Z36_05360	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z36_05365	COG4774	siderophore transport
L2Z36_05375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z36_05380	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z36_05385	COG1535	isochorismatase
L2Z36_05385	COG3433	isochorismatase activity
L2Z36_05400	COG1132	(ABC) transporter
L2Z36_05405	COG1132	(ABC) transporter
L2Z36_05410	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z36_05420	COG1169	isochorismate synthase
L2Z36_05435	COG3739	integral membrane protein
L2Z36_05455	COG3676	manually curated
L2Z36_05470	COG0302	gtp cyclohydrolase
L2Z36_05480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z36_05515	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z36_05530	COG0174	glutamine synthetase
L2Z36_05540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z36_05575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z36_05580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z36_05585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z36_05605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z36_05610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z36_05615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z36_05630	COG1960	acyl-CoA dehydrogenase activity
L2Z36_05635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z36_05640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z36_05650	COG2223	nitrite transmembrane transporter activity
L2Z36_05660	COG0024	Methionine aminopeptidase
L2Z36_05665	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z36_05680	COG2207	Transcriptional regulator
L2Z36_05705	COG2951	lytic endotransglycosylase activity
L2Z36_05710	COG0772	Belongs to the SEDS family
L2Z36_05725	COG0842	Transport permease protein
L2Z36_05730	COG1131	(ABC) transporter
L2Z36_05735	COG0582	viral genome integration into host DNA
L2Z36_05775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z36_05840	COG0305	Participates in initiation and elongation during chromosome replication
L2Z36_05940	COG5410	chromosome segregation
L2Z36_06060	COG0739	heme binding
L2Z36_06170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z36_06185	COG4215	(ABC) transporter
L2Z36_06190	COG4160	amino acid transport
L2Z36_06205	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z36_06210	COG0826	peptidase U32
L2Z36_06215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z36_06230	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z36_06240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z36_06255	COG0642	Histidine kinase
L2Z36_06265	COG0494	nUDIX hydrolase
L2Z36_06275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z36_06280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z36_06285	COG3139	Protein of unknown function (DUF1315)
L2Z36_06290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z36_06295	COG1301	dicarboxylic acid transport
L2Z36_06300	COG1960	acyl-CoA dehydrogenase activity
L2Z36_06305	COG2819	hydrolase of the alpha beta superfamily
L2Z36_06315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z36_06325	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z36_06330	COG1234	tRNA 3'-trailer cleavage
L2Z36_06355	COG2363	Small membrane protein
L2Z36_06380	COG0513	Belongs to the DEAD box helicase family
L2Z36_06390	COG0778	Nitroreductase
L2Z36_06420	COG1286	toxin biosynthetic process
L2Z36_06445	COG4783	chaperone-mediated protein folding
L2Z36_06450	COG1610	YqeY-like protein
L2Z36_06550	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z36_06575	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z36_06580	COG0786	glutamate:sodium symporter activity
L2Z36_06590	COG0583	DNA-binding transcription factor activity
L2Z36_06600	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_06615	COG2186	Transcriptional regulator
L2Z36_06675	COG0477	Major facilitator Superfamily
L2Z36_06700	COG2995	paraquat-inducible protein a
L2Z36_06705	COG3008	intermembrane lipid transfer
L2Z36_06705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z36_06715	COG2351	hydroxyisourate hydrolase activity
L2Z36_06755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2Z36_06765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2Z36_06770	COG0642	Histidine kinase
L2Z36_06775	COG0745	RESPONSE REGULATOR receiver
L2Z36_06795	COG1794	racemase activity, acting on amino acids and derivatives
L2Z36_06825	COG1301	dicarboxylic acid transport
L2Z36_06830	COG3676	manually curated
L2Z36_06840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z36_06845	COG2011	ABC-type metal ion transport system permease component
L2Z36_06850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z36_06855	COG1464	Belongs to the NlpA lipoprotein family
L2Z36_06860	COG0151	Belongs to the GarS family
L2Z36_06865	COG0138	bifunctional purine biosynthesis protein purh
L2Z36_06870	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z36_06900	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z36_06910	COG1305	Transglutaminase-like
L2Z36_06920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z36_06925	COG0305	Participates in initiation and elongation during chromosome replication
L2Z36_06950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z36_06960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z36_06965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z36_06990	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z36_06990	COG0726	polysaccharide deacetylase
L2Z36_06995	COG1215	transferase activity, transferring glycosyl groups
L2Z36_07000	COG3658	cytochrome
L2Z36_07010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z36_07025	COG0583	DNA-binding transcription factor activity
L2Z36_07045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z36_07050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z36_07065	COG1960	acyl-CoA dehydrogenase activity
L2Z36_07070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z36_07075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z36_07100	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z36_07105	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z36_07115	COG2205	protein histidine kinase activity
L2Z36_07120	COG0745	RESPONSE REGULATOR receiver
L2Z36_07125	COG0174	glutamine synthetase
L2Z36_07145	COG0729	surface antigen
L2Z36_07170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z36_07175	COG2814	Major facilitator Superfamily
L2Z36_07190	COG0583	DNA-binding transcription factor activity
L2Z36_07205	COG1187	pseudouridine synthase activity
L2Z36_07225	COG0802	atpase or kinase
L2Z36_07230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z36_07240	COG1923	regulation of RNA biosynthetic process
L2Z36_07245	COG0697	spore germination
L2Z36_07270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z36_07275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z36_07275	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z36_07280	COG4302	ethanolamine ammonia-lyase activity
L2Z36_07285	COG4303	Ethanolamine ammonia lyase large subunit
L2Z36_07290	COG0531	amino acid
L2Z36_07310	COG1454	alcohol dehydrogenase
L2Z36_07315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z36_07340	COG0308	aminopeptidase N
L2Z36_07380	COG1605	Chorismate mutase
L2Z36_07395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
L2Z36_07410	COG1309	transcriptional regulator
L2Z36_07420	COG0668	transmembrane transport
L2Z36_07450	COG4773	Receptor
L2Z36_07470	COG0488	(ABC) transporter
L2Z36_07475	COG0589	response to stress
L2Z36_07495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z36_07505	COG3135	benzoate transporter
L2Z36_07510	COG1522	sequence-specific DNA binding
L2Z36_07520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z36_07525	COG0583	DNA-binding transcription factor activity
L2Z36_07535	COG0183	Belongs to the thiolase family
L2Z36_07545	COG2030	dehydratase
L2Z36_07550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z36_07565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z36_07575	COG0824	Thioesterase
L2Z36_07580	COG1454	alcohol dehydrogenase
L2Z36_07590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z36_07610	COG0069	glutamate synthase activity
L2Z36_07630	COG2814	Major facilitator Superfamily
L2Z36_07645	COG0511	ligase activity, forming carbon-carbon bonds
L2Z36_07665	COG1116	anion transmembrane transporter activity
L2Z36_07665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z36_07670	COG0745	RESPONSE REGULATOR receiver
L2Z36_07680	COG2146	nitrite reductase [NAD(P)H] activity
L2Z36_07680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z36_07685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z36_07690	COG0243	molybdopterin cofactor binding
L2Z36_07700	COG0243	molybdopterin cofactor binding
L2Z36_07705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z36_07720	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z36_07720	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z36_07725	COG0303	'Molybdopterin
L2Z36_07745	COG0697	spore germination
L2Z36_07765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z36_07770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z36_07825	COG2204	response regulator
L2Z36_07830	COG3852	Histidine kinase
L2Z36_07855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z36_07860	COG0575	Belongs to the CDS family
L2Z36_07895	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z36_07910	COG2137	regulation of response to DNA damage stimulus
L2Z36_07920	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z36_07925	COG1011	Hydrolase
L2Z36_07960	COG1113	amino acid transport
L2Z36_07980	COG0659	secondary active sulfate transmembrane transporter activity
L2Z36_07985	COG2135	peptidase activity
L2Z36_08020	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z36_08020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z36_08020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z36_08025	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z36_08030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z36_08030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z36_08060	COG0024	Methionine aminopeptidase
L2Z36_08065	COG0583	DNA-binding transcription factor activity
L2Z36_08075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z36_08080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z36_08085	COG0517	IMP dehydrogenase activity
L2Z36_08085	COG0516	GMP reductase activity
L2Z36_08110	COG0552	protein localization to endoplasmic reticulum
L2Z36_08120	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z36_08130	COG4890	Cyd operon protein YbgT
L2Z36_08135	COG1294	oxidase, subunit
L2Z36_08150	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z36_08160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z36_08165	COG4774	siderophore transport
L2Z36_08180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z36_08185	COG0569	domain protein
L2Z36_08190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z36_08220	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z36_08225	COG0542	response to heat
L2Z36_08250	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z36_08250	COG1902	pentaerythritol trinitrate reductase activity
L2Z36_08295	COG2323	membrane
L2Z36_08300	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z36_08310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z36_08315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z36_08320	COG0183	Belongs to the thiolase family
L2Z36_08325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z36_08330	COG0596	Alpha beta hydrolase
L2Z36_08335	COG2271	Major facilitator Superfamily
L2Z36_08340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z36_08345	COG3485	protocatechuate 3,4-dioxygenase
L2Z36_08350	COG3485	protocatechuate 3,4-dioxygenase
L2Z36_08355	COG0710	3-dehydroquinate dehydratase activity
L2Z36_08360	COG3420	alginic acid biosynthetic process
L2Z36_08365	COG3659	wide pore channel activity
L2Z36_08370	COG4993	Dehydrogenase
L2Z36_08380	COG2391	methyltransferase activity
L2Z36_08395	COG1414	Transcriptional regulator
L2Z36_08400	COG0583	DNA-binding transcription factor activity
L2Z36_08405	COG1960	acyl-CoA dehydrogenase activity
L2Z36_08430	COG2814	Major facilitator Superfamily
L2Z36_08440	COG0154	amidase activity
L2Z36_08460	COG4638	Rieske (2fe-2S)
L2Z36_08470	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_08480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z36_08490	COG3733	amine oxidase
L2Z36_08500	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_08510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z36_08515	COG0183	Belongs to the thiolase family
L2Z36_08520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z36_08525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z36_08535	COG4829	muconolactone delta-isomerase
L2Z36_08540	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z36_08545	COG0583	DNA-binding transcription factor activity
L2Z36_08555	COG2186	Transcriptional regulator
L2Z36_08575	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_08590	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z36_08590	COG1902	pentaerythritol trinitrate reductase activity
L2Z36_08630	COG1309	transcriptional regulator
L2Z36_08640	COG4221	oxidoreductase activity
L2Z36_08645	COG4689	acetoacetate decarboxylase
L2Z36_08655	COG1902	pentaerythritol trinitrate reductase activity
L2Z36_08675	COG1335	isochorismatase
L2Z36_08680	COG0583	DNA-binding transcription factor activity
L2Z36_08690	COG0475	glutathione-regulated potassium exporter activity
L2Z36_08690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z36_08700	COG1473	amidohydrolase
L2Z36_08760	COG2188	Transcriptional regulator
L2Z36_08775	COG0583	DNA-binding transcription factor activity
L2Z36_08790	COG1566	PFAM secretion protein HlyD family protein
L2Z36_08805	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_08810	COG0129	dihydroxy-acid dehydratase activity
L2Z36_08820	COG0583	DNA-binding transcription factor activity
L2Z36_08825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z36_08835	COG2084	Dehydrogenase
L2Z36_08850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z36_08910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z36_08925	COG0556	nucleotide-excision repair
L2Z36_08930	COG3676	manually curated
L2Z36_08970	COG1073	alpha beta
L2Z36_08980	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_08995	COG2207	Transcriptional regulator
L2Z36_09005	COG2205	protein histidine kinase activity
L2Z36_09010	COG0745	RESPONSE REGULATOR receiver
L2Z36_09015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z36_09020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z36_09025	COG1538	Outer membrane efflux protein
L2Z36_09035	COG2072	flavoprotein involved in K transport
L2Z36_09045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z36_09085	COG3539	Fimbrial protein
L2Z36_09110	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z36_09120	COG0753	catalase activity
L2Z36_09135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z36_09200	COG3433	isochorismatase activity
L2Z36_09200	COG1535	isochorismatase
L2Z36_09205	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_09210	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z36_09215	COG4149	molybdate abc transporter
L2Z36_09220	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z36_09230	COG4638	Rieske (2fe-2S)
L2Z36_09235	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z36_09240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z36_09240	COG0543	2 iron, 2 sulfur cluster binding
L2Z36_09255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z36_09300	COG0589	response to stress
L2Z36_09305	COG0659	secondary active sulfate transmembrane transporter activity
L2Z36_09315	COG1002	Type II restriction enzyme, methylase subunits
L2Z36_09320	COG1061	Type III restriction enzyme res subunit
L2Z36_09350	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_09365	COG2207	Transcriptional regulator
L2Z36_09370	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_09375	COG2610	gluconate transmembrane transporter activity
L2Z36_09385	COG0583	DNA-binding transcription factor activity
L2Z36_09400	COG2031	fatty acid transporter
L2Z36_09405	COG0183	Belongs to the thiolase family
L2Z36_09410	COG0583	DNA-binding transcription factor activity
L2Z36_09415	COG0583	DNA-binding transcription factor activity
L2Z36_09430	COG1027	Aspartate ammonia-lyase
L2Z36_09440	COG0477	Major facilitator Superfamily
L2Z36_09460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z36_09465	COG4521	taurine ABC transporter
L2Z36_09480	COG2188	Transcriptional regulator
L2Z36_09490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z36_09495	COG1733	regulation of RNA biosynthetic process
L2Z36_09500	COG2207	Transcriptional regulator
L2Z36_09500	COG3708	Transcriptional regulator
L2Z36_09515	COG0730	response to heat
L2Z36_09530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z36_09530	COG3453	Protein conserved in bacteria
L2Z36_09540	COG3781	membrane
L2Z36_09545	COG1063	alcohol dehydrogenase
L2Z36_09555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z36_09560	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z36_09565	COG0022	dehydrogenase e1 component
L2Z36_09570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z36_09575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z36_09590	COG3706	GGDEF domain
L2Z36_09605	COG0133	tryptophan synthase activity
L2Z36_09615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z36_09650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z36_09675	COG2226	methyltransferase
L2Z36_09730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z36_09735	COG4773	Receptor
L2Z36_09755	COG0730	response to heat
L2Z36_09760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z36_09775	COG0406	alpha-ribazole phosphatase activity
L2Z36_09780	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z36_09795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z36_09825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z36_09835	COG4264	IucA IucC family
L2Z36_09840	COG4264	IucA IucC family
L2Z36_09845	COG2814	Major facilitator Superfamily
L2Z36_09860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z36_09875	COG1960	acyl-CoA dehydrogenase activity
L2Z36_09880	COG1960	acyl-CoA dehydrogenase activity
L2Z36_09885	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z36_09890	COG2207	Transcriptional regulator
L2Z36_09895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z36_09900	COG0776	regulation of translation
L2Z36_09925	COG0822	iron-sulfur transferase activity
L2Z36_09930	COG0316	Belongs to the HesB IscA family
L2Z36_09960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z36_09980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z36_09985	COG0702	epimerase
L2Z36_10020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z36_10030	COG0339	signal peptide processing
L2Z36_10050	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
L2Z36_10075	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z36_10080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z36_10110	COG0776	regulation of translation
L2Z36_10175	COG0084	hydrolase, TatD family'
L2Z36_10195	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z36_10200	COG1132	(ABC) transporter
L2Z36_10210	COG0811	peptide transport
L2Z36_10215	COG1475	DNA binding
L2Z36_10220	COG1192	Involved in chromosome partitioning
L2Z36_10230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z36_10245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z36_10250	COG0191	fructose-bisphosphate aldolase activity
L2Z36_10270	COG0424	maF-like protein
L2Z36_10275	COG2850	peptidyl-arginine hydroxylation
L2Z36_10285	COG0640	Transcriptional regulator
L2Z36_10295	COG3619	membrane
L2Z36_10300	COG3122	Protein conserved in bacteria
L2Z36_10305	COG1132	(ABC) transporter
L2Z36_10325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z36_10330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z36_10340	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z36_10340	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z36_10340	COG0506	proline dehydrogenase activity
L2Z36_10345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z36_10360	COG3698	Phosphodiester glycosidase
L2Z36_10370	COG2353	YceI-like domain
L2Z36_10385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z36_10430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z36_10430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z36_10455	COG3539	Fimbrial protein
L2Z36_10460	COG3121	Chaperone
L2Z36_10485	COG0697	spore germination
L2Z36_10495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z36_10505	COG0583	DNA-binding transcription factor activity
L2Z36_10540	COG1522	sequence-specific DNA binding
L2Z36_10550	COG1126	abc transporter atp-binding protein
L2Z36_10555	COG0765	amino acid transport
L2Z36_10560	COG0765	amino acid transport
L2Z36_10590	COG1464	Belongs to the NlpA lipoprotein family
L2Z36_10600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z36_10605	COG2011	ABC-type metal ion transport system permease component
L2Z36_10610	COG0012	GTP binding
L2Z36_10635	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z36_10675	COG0386	Belongs to the glutathione peroxidase family
L2Z36_10685	COG0436	Aminotransferase
L2Z36_10690	COG1301	dicarboxylic acid transport
L2Z36_10725	COG3634	alkyl hydroperoxide reductase activity
L2Z36_10740	COG0583	DNA-binding transcription factor activity
L2Z36_10745	COG0798	PFAM Bile acid sodium symporter
L2Z36_10750	COG0640	Transcriptional regulator
L2Z36_10765	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z36_10775	COG0583	DNA-binding transcription factor activity
L2Z36_10785	COG1953	Uracil, thiamine, allantoin
L2Z36_10795	COG2175	clavaminate synthase activity
L2Z36_10800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z36_10805	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z36_10810	COG4521	taurine ABC transporter
L2Z36_10820	COG0477	Major facilitator Superfamily
L2Z36_10845	COG1271	oxidase subunit
L2Z36_10850	COG1294	oxidase, subunit
L2Z36_10860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z36_10880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z36_10900	COG3052	prosthetic group binding
L2Z36_10905	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z36_10915	COG2814	Major facilitator Superfamily
L2Z36_10930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z36_10935	COG1346	cytolysis
L2Z36_10945	COG0583	DNA-binding transcription factor activity
L2Z36_10950	COG0625	glutathione transferase activity
L2Z36_10955	COG0625	glutathione transferase activity
L2Z36_10960	COG0583	DNA-binding transcription factor activity
L2Z36_10975	COG1045	serine acetyltransferase
L2Z36_10980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z36_10985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z36_10995	COG1280	lysine exporter protein (LysE YggA)
L2Z36_11010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z36_11015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z36_11020	COG1126	abc transporter atp-binding protein
L2Z36_11025	COG0765	amino acid transport
L2Z36_11030	COG0765	amino acid transport
L2Z36_11050	COG0784	Response regulator, receiver
L2Z36_11050	COG2205	protein histidine kinase activity
L2Z36_11095	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_11145	COG0583	DNA-binding transcription factor activity
L2Z36_11165	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z36_11170	COG1309	transcriptional regulator
L2Z36_11175	COG1960	acyl-CoA dehydrogenase activity
L2Z36_11180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z36_11185	COG1024	Enoyl-CoA hydratase
L2Z36_11190	COG4770	biotin carboxylase activity
L2Z36_11200	COG0583	DNA-binding transcription factor activity
L2Z36_11215	COG1960	acyl-CoA dehydrogenase activity
L2Z36_11225	COG2814	Major facilitator Superfamily
L2Z36_11235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z36_11240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z36_11245	COG2814	Major facilitator Superfamily
L2Z36_11250	COG1960	acyl-CoA dehydrogenase activity
L2Z36_11255	COG1024	Enoyl-CoA hydratase
L2Z36_11260	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_11265	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z36_11270	COG0183	Belongs to the thiolase family
L2Z36_11280	COG2814	Major facilitator Superfamily
L2Z36_11290	COG1024	Enoyl-CoA hydratase
L2Z36_11300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z36_11305	COG1960	acyl-CoA dehydrogenase activity
L2Z36_11310	COG2814	Major facilitator Superfamily
L2Z36_11315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z36_11320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z36_11335	COG3842	ATPase activity
L2Z36_11340	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z36_11350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z36_11355	COG1414	Transcriptional regulator
L2Z36_11365	COG0583	DNA-binding transcription factor activity
L2Z36_11370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z36_11375	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_11385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z36_11395	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_11400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z36_11405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z36_11410	COG2267	carboxylic ester hydrolase activity
L2Z36_11430	COG3038	cytochrome b561
L2Z36_11440	COG2271	Major facilitator Superfamily
L2Z36_11445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z36_11450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z36_11480	COG1278	Cold shock
L2Z36_11515	COG0210	DNA helicase
L2Z36_11520	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L2Z36_11525	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z36_11535	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z36_11540	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z36_11545	COG0183	Belongs to the thiolase family
L2Z36_11550	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z36_11555	COG1024	Enoyl-CoA hydratase
L2Z36_11560	COG1024	Enoyl-CoA hydratase
L2Z36_11565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z36_11570	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z36_11575	COG3396	Phenylacetate-CoA oxygenase
L2Z36_11580	COG3460	Phenylacetate-CoA oxygenase
L2Z36_11585	COG3396	Phenylacetate-CoA oxygenase
L2Z36_11590	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_11590	COG2030	dehydratase
L2Z36_11595	COG1760	l-serine dehydratase
L2Z36_11600	COG0531	amino acid
L2Z36_11605	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_11630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z36_11650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z36_11660	COG0789	Transcriptional regulator
L2Z36_11670	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z36_11685	COG2807	transmembrane transport
L2Z36_11690	COG0590	tRNA wobble adenosine to inosine editing
L2Z36_11810	COG1116	anion transmembrane transporter activity
L2Z36_11815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z36_11825	COG0864	Transcriptional regulator
L2Z36_11835	COG1733	regulation of RNA biosynthetic process
L2Z36_11840	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z36_11845	COG0439	Biotin carboxylase
L2Z36_11860	COG1063	alcohol dehydrogenase
L2Z36_11870	COG1309	transcriptional regulator
L2Z36_11895	COG0038	chloride channel
L2Z36_11900	COG4770	biotin carboxylase activity
L2Z36_11920	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z36_11925	COG0583	DNA-binding transcription factor activity
L2Z36_11945	COG3209	COG3209 Rhs family protein
L2Z36_11990	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z36_12010	COG2814	Major facilitator Superfamily
L2Z36_12025	COG1560	Kdo2-lipid A biosynthetic process
L2Z36_12035	COG5006	permease, DMT superfamily
L2Z36_12040	COG1522	sequence-specific DNA binding
L2Z36_12055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z36_12065	COG4122	O-methyltransferase activity
L2Z36_12095	COG1538	Outer membrane efflux protein
L2Z36_12100	COG1137	ATPase activity
L2Z36_12105	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z36_12115	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z36_12175	COG5434	Belongs to the glycosyl hydrolase 28 family
L2Z36_12190	COG3566	protein conserved in bacteria
L2Z36_12210	COG3567	Phage-associated protein, HI1409 family
L2Z36_12215	COG5410	chromosome segregation
L2Z36_12285	COG2814	Major facilitator Superfamily
L2Z36_12320	COG1278	Cold shock
L2Z36_12325	COG1280	lysine exporter protein (LysE YggA)
L2Z36_12355	COG1570	exodeoxyribonuclease VII activity
L2Z36_12405	COG0583	DNA-binding transcription factor activity
L2Z36_12415	COG4638	Rieske (2fe-2S)
L2Z36_12425	COG0543	2 iron, 2 sulfur cluster binding
L2Z36_12425	COG0633	Ferredoxin
L2Z36_12430	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_12435	COG3135	benzoate transporter
L2Z36_12440	COG2814	Major facilitator Superfamily
L2Z36_12455	COG1643	Atp-dependent helicase
L2Z36_12460	COG0450	alkyl hydroperoxide reductase
L2Z36_12480	COG3634	alkyl hydroperoxide reductase activity
L2Z36_12500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z36_12505	COG0625	glutathione transferase activity
L2Z36_12515	COG2885	chlorophyll binding
L2Z36_12550	COG0542	response to heat
L2Z36_12565	COG1765	OsmC-like protein
L2Z36_12580	COG0667	Aldo Keto reductase
L2Z36_12595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z36_12605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z36_12615	COG0527	aspartate kinase activity
L2Z36_12625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z36_12635	COG3038	cytochrome b561
L2Z36_12640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z36_12645	COG2252	PERMEase
L2Z36_12655	COG2072	flavoprotein involved in K transport
L2Z36_12670	COG1741	Belongs to the pirin family
L2Z36_12675	COG1309	transcriptional regulator
L2Z36_12685	COG0300	oxidoreductase activity
L2Z36_12690	COG2072	flavoprotein involved in K transport
L2Z36_12695	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L2Z36_12740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z36_12755	COG2814	Major facilitator Superfamily
L2Z36_12760	COG1024	Enoyl-CoA hydratase
L2Z36_12765	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_12775	COG1960	acyl-CoA dehydrogenase activity
L2Z36_12800	COG2186	Transcriptional regulator
L2Z36_12805	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_12815	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z36_12820	COG2271	Major facilitator Superfamily
L2Z36_12825	COG2721	sulfolactate sulfo-lyase activity
L2Z36_12830	COG0697	spore germination
L2Z36_12860	COG1113	amino acid transport
L2Z36_12880	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_12900	COG0531	amino acid
L2Z36_12910	COG1113	amino acid transport
L2Z36_12945	COG3209	COG3209 Rhs family protein
L2Z36_12975	COG1902	pentaerythritol trinitrate reductase activity
L2Z36_12975	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z36_12985	COG3706	GGDEF domain
L2Z36_12985	COG5001	Diguanylate cyclase
L2Z36_12985	COG2203	Gaf domain
L2Z36_12985	COG4251	negative regulation of phosphorylation
L2Z36_12995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z36_13050	COG4172	Belongs to the ABC transporter superfamily
L2Z36_13055	COG4239	(ABC) transporter, permease
L2Z36_13060	COG4174	ABC transporter (Permease)
L2Z36_13070	COG0741	lytic transglycosylase activity
L2Z36_13070	COG0741	lytic transglycosylase activity
L2Z36_13070	COG1388	LysM domain
L2Z36_13070	COG1388	LysM domain
L2Z36_13075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z36_13115	COG0583	DNA-binding transcription factor activity
L2Z36_13120	COG1279	arginine transmembrane transporter activity
L2Z36_13140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z36_13145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z36_13150	COG0006	proline dipeptidase activity
L2Z36_13190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z36_13210	COG3384	dioxygenase
L2Z36_13220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z36_13225	COG2878	Part of a membrane complex involved in electron transport
L2Z36_13230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z36_13255	COG0768	penicillin binding
L2Z36_13260	COG0742	ribosomal rna small subunit methyltransferase
L2Z36_13275	COG0830	nickel cation binding
L2Z36_13285	COG0804	urea catabolic process
L2Z36_13325	COG1253	flavin adenine dinucleotide binding
L2Z36_13330	COG2851	Citrate transporter
L2Z36_13380	COG1773	rubredoxin
L2Z36_13385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z36_13395	COG0583	DNA-binding transcription factor activity
L2Z36_13425	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z36_13430	COG4181	ATPase activity
L2Z36_13475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z36_13495	COG0306	phosphate transporter
L2Z36_13505	COG3958	Transketolase
L2Z36_13510	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z36_13515	COG2271	Major facilitator Superfamily
L2Z36_13520	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_13525	COG0583	DNA-binding transcription factor activity
L2Z36_13540	COG2223	nitrite transmembrane transporter activity
L2Z36_13545	COG2207	Transcriptional regulator
L2Z36_13550	COG2066	Belongs to the glutaminase family
L2Z36_13555	COG0242	peptide deformylase activity
L2Z36_13560	COG0477	Major facilitator Superfamily
L2Z36_13570	COG0028	Belongs to the TPP enzyme family
L2Z36_13585	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_13590	COG2267	carboxylic ester hydrolase activity
L2Z36_13600	COG2271	Major facilitator Superfamily
L2Z36_13605	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z36_13615	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_13635	COG1414	Transcriptional regulator
L2Z36_13650	COG1024	Enoyl-CoA hydratase
L2Z36_13660	COG1215	transferase activity, transferring glycosyl groups
L2Z36_13665	COG0726	polysaccharide deacetylase
L2Z36_13665	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z36_13675	COG4681	YaeQ
L2Z36_13685	COG0523	cobalamin synthesis protein
L2Z36_13695	COG1607	acyl-coa hydrolase
L2Z36_13705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z36_13710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z36_13715	COG1309	transcriptional regulator
L2Z36_13745	COG2040	homocysteine
L2Z36_13750	COG0531	amino acid
L2Z36_13805	COG1595	DNA-templated transcription, initiation
L2Z36_13815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z36_13820	COG0477	Major facilitator Superfamily
L2Z36_13840	COG0084	hydrolase, TatD family'
L2Z36_13880	COG0629	single-stranded DNA binding
L2Z36_13935	COG0582	viral genome integration into host DNA
L2Z36_13945	COG0405	Gamma-glutamyltransferase
L2Z36_13950	COG2814	Major facilitator Superfamily
L2Z36_13960	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z36_13975	COG1090	epimerase
L2Z36_13995	COG0420	3'-5' exonuclease activity
L2Z36_14020	COG0735	belongs to the Fur family
L2Z36_14025	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z36_14045	COG0121	glutamine amidotransferase
L2Z36_14060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z36_14070	COG0210	DNA helicase
L2Z36_14075	COG2885	chlorophyll binding
L2Z36_14080	COG0204	Acyl-transferase
L2Z36_14095	COG2894	cell division
L2Z36_14110	COG1280	lysine exporter protein (LysE YggA)
L2Z36_14115	COG1674	ftsk spoiiie
L2Z36_14115	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z36_14120	COG0492	ferredoxin-NADP+ reductase activity
L2Z36_14125	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z36_14135	COG0456	acetyltransferase
L2Z36_14180	COG1981	membrane
L2Z36_14195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z36_14195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z36_14215	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_14225	COG0657	acetylesterase activity
L2Z36_14235	COG0473	3-isopropylmalate dehydrogenase activity
L2Z36_14240	COG0583	DNA-binding transcription factor activity
L2Z36_14260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z36_14285	COG0564	pseudouridine synthase activity
L2Z36_14295	COG0358	DNA primase activity
L2Z36_14310	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z36_14340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z36_14370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z36_14380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z36_14380	COG0352	thiamine-phosphate diphosphorylase activity
L2Z36_14380	COG0351	phosphomethylpyrimidine kinase
L2Z36_14385	COG1652	LysM domain
L2Z36_14410	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z36_14415	COG3101	peptidyl-lysine hydroxylation
L2Z36_14420	COG0009	L-threonylcarbamoyladenylate synthase
L2Z36_14425	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z36_14430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z36_14445	COG4106	trans-aconitate 2-methyltransferase activity
L2Z36_14460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z36_14460	COG0596	Alpha beta hydrolase
L2Z36_14460	COG2226	methyltransferase
L2Z36_14470	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z36_14475	COG2223	nitrite transmembrane transporter activity
L2Z36_14495	COG1196	nuclear chromosome segregation
L2Z36_14505	COG0730	response to heat
L2Z36_14520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z36_14530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z36_14580	COG0489	protein tyrosine kinase activity
L2Z36_14590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z36_14590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z36_14620	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z36_14625	COG2081	HI0933 family
L2Z36_14635	COG0668	transmembrane transport
L2Z36_14655	COG0583	DNA-binding transcription factor activity
L2Z36_14680	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z36_14685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z36_14715	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z36_14755	COG0745	RESPONSE REGULATOR receiver
L2Z36_14775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z36_14785	COG0384	phenazine biosynthesis protein PhzF
L2Z36_14815	COG1309	transcriptional regulator
L2Z36_14820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z36_14835	COG0583	DNA-binding transcription factor activity
L2Z36_14865	COG0583	DNA-binding transcription factor activity
L2Z36_14880	COG0583	DNA-binding transcription factor activity
L2Z36_14885	COG1053	succinate dehydrogenase
L2Z36_14895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z36_14900	COG2814	Major facilitator Superfamily
L2Z36_14905	COG1960	acyl-CoA dehydrogenase activity
L2Z36_14910	COG0583	DNA-binding transcription factor activity
L2Z36_14915	COG1063	alcohol dehydrogenase
L2Z36_14945	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z36_14950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z36_14955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z36_14970	COG3667	copper resistance
L2Z36_14975	COG2132	Multicopper oxidase
L2Z36_14985	COG0561	phosphatase activity
L2Z36_14990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z36_15000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L2Z36_15015	COG1214	PFAM Peptidase M22, glycoprotease
L2Z36_15065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z36_15075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z36_15080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z36_15085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z36_15145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z36_15155	COG1846	Transcriptional regulator
L2Z36_15160	COG1764	response to oxidative stress
L2Z36_15200	COG0037	tRNA processing
L2Z36_15210	COG0248	Ppx GppA phosphatase
L2Z36_15240	COG0072	phenylalanine-tRNA ligase activity
L2Z36_15280	COG1238	metal cluster binding
L2Z36_15285	COG0625	glutathione transferase activity
L2Z36_15300	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z36_15305	COG3028	Belongs to the UPF0307 family
L2Z36_15310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z36_15330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z36_15335	COG0617	tRNA 3'-terminal CCA addition
L2Z36_15340	COG1555	photosystem II stabilization
L2Z36_15345	COG3956	TIGRFAM MazG family protein
L2Z36_15355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z36_15375	COG0784	Response regulator, receiver
L2Z36_15375	COG2205	protein histidine kinase activity
L2Z36_15375	COG5002	protein histidine kinase activity
L2Z36_15380	COG1024	Enoyl-CoA hydratase
L2Z36_15385	COG2084	Dehydrogenase
L2Z36_15390	COG3622	Belongs to the hyi family
L2Z36_15420	COG0697	spore germination
L2Z36_15430	COG2814	Major facilitator Superfamily
L2Z36_15450	COG2132	Multicopper oxidase
L2Z36_15465	COG2205	protein histidine kinase activity
L2Z36_15555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z36_15565	COG0583	DNA-binding transcription factor activity
L2Z36_15575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z36_15585	COG0084	hydrolase, TatD family'
L2Z36_15600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z36_15620	COG3676	manually curated
L2Z36_15635	COG0440	acetolactate synthase activity
L2Z36_15640	COG0028	Belongs to the TPP enzyme family
L2Z36_15665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z36_15670	COG0577	efflux transmembrane transporter activity
L2Z36_15670	COG1136	(ABC) transporter
L2Z36_15675	COG1538	Outer membrane efflux protein
L2Z36_15690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z36_15695	COG1162	GTPase activity
L2Z36_15705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z36_15745	COG1426	Protein conserved in bacteria
L2Z36_15780	COG0793	Belongs to the peptidase S41A family
L2Z36_15795	COG2267	carboxylic ester hydrolase activity
L2Z36_15805	COG1012	belongs to the aldehyde dehydrogenase family
L2Z36_15810	COG3265	gluconokinase activity
L2Z36_15820	COG0800	Aldolase
L2Z36_15830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z36_15835	COG0857	belongs to the CobB CobQ family
L2Z36_15835	COG0280	phosphate acetyltransferase
L2Z36_15840	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z36_15840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z36_15860	COG0740	serine-type endopeptidase activity
L2Z36_15870	COG4774	siderophore transport
L2Z36_15880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z36_15890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z36_15890	COG2813	Specifically methylates the guanine in position
L2Z36_15990	COG0788	formyltetrahydrofolate deformylase activity
L2Z36_16015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z36_16015	COG4651	solute:proton antiporter activity
L2Z36_16035	COG0724	RNA recognition motif
L2Z36_16040	COG0210	DNA helicase
L2Z36_16065	COG1733	regulation of RNA biosynthetic process
L2Z36_16075	COG2900	Belongs to the SlyX family
L2Z36_16080	COG0488	(ABC) transporter
L2Z36_16085	COG1280	lysine exporter protein (LysE YggA)
L2Z36_16090	COG1560	Kdo2-lipid A biosynthetic process
L2Z36_16100	COG1301	dicarboxylic acid transport
L2Z36_16155	COG0473	3-isopropylmalate dehydrogenase activity
L2Z36_16210	COG0583	DNA-binding transcription factor activity
L2Z36_16220	COG0625	glutathione transferase activity
L2Z36_16225	COG2378	regulation of single-species biofilm formation
L2Z36_16230	COG0546	phosphoglycolate phosphatase activity
L2Z36_16245	COG1530	ribonuclease E activity
L2Z36_16250	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z36_16265	COG0583	DNA-binding transcription factor activity
L2Z36_16270	COG4221	oxidoreductase activity
L2Z36_16275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z36_16285	COG0534	Mate efflux family protein
L2Z36_16300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z36_16325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z36_16325	COG0493	'glutamate synthase
L2Z36_16335	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z36_16340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z36_16355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z36_16365	COG0644	oxidoreductase
L2Z36_16365	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z36_16375	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z36_16380	COG4535	Mg2 and Co2 transporter CorC
L2Z36_16390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z36_16410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z36_16415	COG0475	glutathione-regulated potassium exporter activity
L2Z36_16415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z36_16430	COG0484	heat shock protein binding
L2Z36_16435	COG0789	Transcriptional regulator
L2Z36_16440	COG0598	Magnesium transport protein CorA
L2Z36_16455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z36_16460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z36_16465	COG1074	ATP-dependent DNA helicase activity
L2Z36_16470	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z36_16490	COG2226	methyltransferase
L2Z36_16505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z36_16510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z36_16525	COG2111	Na H antiporter
L2Z36_16525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z36_16530	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z36_16535	COG0651	ATP synthesis coupled electron transport
L2Z36_16540	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z36_16545	COG2212	antiporter activity
L2Z36_16550	COG1320	monovalent cation:proton antiporter activity
L2Z36_16565	COG0195	Participates in both transcription termination and antitermination
L2Z36_16615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z36_16620	COG0237	dephospho-CoA kinase activity
L2Z36_16630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z36_16645	COG0497	DNA recombination
L2Z36_16655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z36_16685	COG2169	Transcriptional regulator
L2Z36_16685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z36_16690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z36_16750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z36_16765	COG0326	Molecular chaperone. Has ATPase activity
L2Z36_16780	COG2056	Na+-H+ antiporter family
L2Z36_16880	COG0546	phosphoglycolate phosphatase activity
L2Z36_16885	COG1716	ATPase activity
L2Z36_16930	COG0181	hydroxymethylbilane synthase activity
L2Z36_16940	COG3275	phosphorelay sensor kinase activity
L2Z36_16960	COG1538	Outer membrane efflux protein
L2Z36_16965	COG0697	spore germination
L2Z36_16990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z36_16995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z36_17000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z36_17005	COG0772	Belongs to the SEDS family
L2Z36_17030	COG4974	Belongs to the 'phage' integrase family
L2Z36_17035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z36_17045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z36_17055	COG2197	response regulator
L2Z36_17070	COG0793	Belongs to the peptidase S41A family
L2Z36_17075	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z36_17080	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z36_17120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z36_17120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z36_17130	COG0004	ammonium transporteR
L2Z36_17135	COG0347	Belongs to the P(II) protein family
L2Z36_17155	COG0659	secondary active sulfate transmembrane transporter activity
L2Z36_17180	COG0789	Transcriptional regulator
L2Z36_17195	COG0640	Transcriptional regulator
L2Z36_17205	COG0798	PFAM Bile acid sodium symporter
L2Z36_17210	COG0431	NADPH-dependent FMN reductase
L2Z36_17215	COG0492	ferredoxin-NADP+ reductase activity
L2Z36_17220	COG2072	flavoprotein involved in K transport
L2Z36_17265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z36_17280	COG3676	manually curated
L2Z36_17290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z36_17305	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z36_17315	COG0477	Major facilitator Superfamily
L2Z36_17320	COG2860	membrane
L2Z36_17325	COG3012	SEC-C Motif Domain Protein
L2Z36_17330	COG1253	flavin adenine dinucleotide binding
L2Z36_17340	COG0477	Major facilitator Superfamily
L2Z36_17350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z36_17390	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z36_17400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z36_17470	COG0758	DNA mediated transformation
L2Z36_17480	COG0697	spore germination
L2Z36_17485	COG1309	transcriptional regulator
L2Z36_17500	COG0386	Belongs to the glutathione peroxidase family
L2Z36_17565	COG1121	(ABC) transporter
L2Z36_17570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z36_17575	COG1280	lysine exporter protein (LysE YggA)
L2Z36_17580	COG2837	iron assimilation
L2Z36_17585	COG0281	malic enzyme
L2Z36_17630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z36_17630	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z36_17635	COG4399	Belongs to the UPF0754 family
L2Z36_17640	COG2259	Doxx family
L2Z36_17645	COG0586	Pfam SNARE associated Golgi protein
L2Z36_17660	COG1192	Involved in chromosome partitioning
L2Z36_17670	COG0271	Belongs to the BolA IbaG family
L2Z36_17690	COG2267	carboxylic ester hydrolase activity
L2Z36_17710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z36_17710	COG3321	synthase
L2Z36_17710	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z36_17710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z36_17715	COG1960	acyl-CoA dehydrogenase activity
L2Z36_17725	COG2197	response regulator
L2Z36_17735	COG3916	Acyl-homoserine-lactone synthase
L2Z36_17740	COG0477	Major facilitator Superfamily
L2Z36_17745	COG1024	Enoyl-CoA hydratase
L2Z36_17750	COG1024	Enoyl-CoA hydratase
L2Z36_17755	COG1960	acyl-CoA dehydrogenase activity
L2Z36_17760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z36_17780	COG1113	amino acid transport
L2Z36_17785	COG1113	amino acid transport
L2Z36_17790	COG0251	oxidation-reduction process
L2Z36_17830	COG0564	pseudouridine synthase activity
L2Z36_17845	COG3328	transposase activity
L2Z36_17870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z36_17885	COG1802	Transcriptional regulator
L2Z36_17890	COG1448	Aminotransferase
L2Z36_17895	COG0277	FAD linked oxidase domain protein
L2Z36_17905	COG2186	Transcriptional regulator
L2Z36_17915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z36_17920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z36_17935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z36_17950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z36_17960	COG0110	maltose O-acetyltransferase activity
L2Z36_17965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z36_17975	COG0438	transferase activity, transferring glycosyl groups
L2Z36_17980	COG0438	transferase activity, transferring glycosyl groups
L2Z36_17990	COG0438	transferase activity, transferring glycosyl groups
L2Z36_18005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z36_18010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z36_18015	COG1596	polysaccharide export
L2Z36_18040	COG0728	peptidoglycan biosynthetic process
L2Z36_18045	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z36_18100	COG0546	phosphoglycolate phosphatase activity
L2Z36_18105	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z36_18125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z36_18130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z36_18135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z36_18140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z36_18150	COG1309	transcriptional regulator
L2Z36_18155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z36_18165	COG0196	riboflavin kinase activity
L2Z36_18170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z36_18180	COG1047	Peptidyl-prolyl cis-trans
L2Z36_18220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z36_18225	COG0657	acetylesterase activity
L2Z36_18245	COG0583	DNA-binding transcription factor activity
L2Z36_18275	COG2951	lytic endotransglycosylase activity
L2Z36_18280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z36_18295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z36_18305	COG0671	phosphoesterase, PA-phosphatase related
L2Z36_18310	COG0861	Integral membrane protein TerC family
L2Z36_18320	COG0754	glutathionylspermidine amidase activity
L2Z36_18330	COG0402	S-adenosylhomocysteine deaminase activity
L2Z36_18345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z36_18350	COG1230	cation diffusion facilitator family transporter
L2Z36_18365	COG0706	membrane insertase activity
L2Z36_18390	COG0592	DNA-directed DNA polymerase activity
L2Z36_18400	COG0187	DNA topoisomerase II activity
L2Z36_18410	COG0586	Pfam SNARE associated Golgi protein
L2Z36_18415	COG0488	(ABC) transporter
L2Z36_18440	COG0596	Alpha beta hydrolase
L2Z36_18445	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z36_18450	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)