locus-tag	class	description
L2Z41_00010	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_00015	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z41_00025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z41_00035	COG2233	PERMEase
L2Z41_00040	COG2351	hydroxyisourate hydrolase activity
L2Z41_00075	COG3706	GGDEF domain
L2Z41_00090	COG1393	Belongs to the ArsC family
L2Z41_00095	COG0708	Exodeoxyribonuclease III
L2Z41_00115	COG0189	ligase activity
L2Z41_00135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z41_00145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z41_00160	COG4942	peptidase
L2Z41_00170	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z41_00180	COG2119	membrane
L2Z41_00185	COG4774	siderophore transport
L2Z41_00190	COG0426	domain, Protein
L2Z41_00190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z41_00215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z41_00235	COG1902	pentaerythritol trinitrate reductase activity
L2Z41_00240	COG1519	Transferase
L2Z41_00245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z41_00250	COG0668	transmembrane transport
L2Z41_00260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z41_00265	COG1335	isochorismatase
L2Z41_00270	COG1522	sequence-specific DNA binding
L2Z41_00275	COG3328	transposase activity
L2Z41_00300	COG0784	Response regulator, receiver
L2Z41_00300	COG2198	Histidine kinase
L2Z41_00300	COG2205	protein histidine kinase activity
L2Z41_00305	COG3162	membrane
L2Z41_00310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z41_00320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z41_00340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z41_00345	COG1309	transcriptional regulator
L2Z41_00365	COG0352	thiamine-phosphate diphosphorylase activity
L2Z41_00365	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z41_00365	COG0351	phosphomethylpyrimidine kinase
L2Z41_00375	COG2814	Major facilitator Superfamily
L2Z41_00390	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z41_00400	COG1113	amino acid transport
L2Z41_00410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z41_00415	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_00425	COG1335	isochorismatase
L2Z41_00455	COG2814	Major facilitator Superfamily
L2Z41_00460	COG0583	DNA-binding transcription factor activity
L2Z41_00480	COG0667	Aldo Keto reductase
L2Z41_00515	COG1733	regulation of RNA biosynthetic process
L2Z41_00520	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z41_00585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z41_00600	COG2329	Antibiotic biosynthesis monooxygenase
L2Z41_00630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z41_00660	COG0427	acetyl-CoA hydrolase
L2Z41_00685	COG0659	secondary active sulfate transmembrane transporter activity
L2Z41_00690	COG4221	oxidoreductase activity
L2Z41_00695	COG2873	o-acetylhomoserine
L2Z41_00700	COG0488	(ABC) transporter
L2Z41_00785	COG0833	amino acid
L2Z41_00830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z41_00835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z41_00850	COG2226	methyltransferase
L2Z41_00900	COG0069	glutamate synthase activity
L2Z41_00900	COG0067	glutamate synthase
L2Z41_00900	COG0070	glutamate synthase
L2Z41_00905	COG0493	'glutamate synthase
L2Z41_00915	COG1704	LemA family
L2Z41_00920	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z41_00940	COG3307	-O-antigen
L2Z41_00960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z41_00975	COG0194	GDP metabolic process
L2Z41_01025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z41_01045	COG5380	lipid catabolic process
L2Z41_01050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z41_01075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z41_01080	COG0277	FAD linked oxidase domain protein
L2Z41_01090	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z41_01095	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z41_01110	COG1289	transmembrane transporter activity
L2Z41_01120	COG0628	permease
L2Z41_01125	COG1192	Involved in chromosome partitioning
L2Z41_01155	COG0833	amino acid
L2Z41_01160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z41_01165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z41_01175	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_01215	COG0583	DNA-binding transcription factor activity
L2Z41_01260	COG0517	IMP dehydrogenase activity
L2Z41_01265	COG1983	PspC domain protein
L2Z41_01275	COG1960	acyl-CoA dehydrogenase activity
L2Z41_01290	COG0408	coproporphyrinogen oxidase activity
L2Z41_01310	COG0513	Belongs to the DEAD box helicase family
L2Z41_01320	COG1127	ABC transporter
L2Z41_01325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z41_01335	COG2854	intermembrane phospholipid transfer
L2Z41_01345	COG0598	Magnesium transport protein CorA
L2Z41_01355	COG0494	nUDIX hydrolase
L2Z41_01360	COG1040	competence protein
L2Z41_01365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z41_01385	COG1946	Acyl-CoA thioesterase
L2Z41_01390	COG1301	dicarboxylic acid transport
L2Z41_01405	COG1959	2 iron, 2 sulfur cluster binding
L2Z41_01410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z41_01410	COG1017	nitric oxide dioxygenase activity
L2Z41_01415	COG0433	COG0433 Predicted ATPase
L2Z41_01420	COG0626	cystathionine gamma-synthase activity
L2Z41_01575	COG1960	acyl-CoA dehydrogenase activity
L2Z41_01580	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z41_01610	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z41_01615	COG0339	signal peptide processing
L2Z41_01620	COG0557	exoribonuclease II activity
L2Z41_01665	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z41_01670	COG2169	Transcriptional regulator
L2Z41_01675	COG0697	spore germination
L2Z41_01680	COG1295	ribonuclease BN
L2Z41_01715	COG1702	phosphate starvation-inducible protein PhoH
L2Z41_01725	COG0741	lytic transglycosylase activity
L2Z41_01725	COG0739	heme binding
L2Z41_01725	COG1196	nuclear chromosome segregation
L2Z41_01760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z41_01765	COG1183	phosphatidylcholine synthase activity
L2Z41_01810	COG1960	acyl-CoA dehydrogenase activity
L2Z41_01815	COG1309	transcriptional regulator
L2Z41_01830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z41_01835	COG1960	acyl-CoA dehydrogenase activity
L2Z41_01855	COG2969	positive regulation of protein catabolic process
L2Z41_01865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z41_01880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z41_01885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z41_01905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z41_01915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z41_01920	COG1408	metallophosphoesterase
L2Z41_01930	COG2199	diguanylate cyclase activity
L2Z41_01990	COG1607	acyl-coa hydrolase
L2Z41_02020	COG2350	Protein conserved in bacteria
L2Z41_02030	COG0613	PHP domain protein
L2Z41_02035	COG3781	membrane
L2Z41_02045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z41_02050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z41_02060	COG1862	Preprotein translocase
L2Z41_02090	COG2205	protein histidine kinase activity
L2Z41_02095	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z41_02115	COG0726	polysaccharide deacetylase
L2Z41_02120	COG0463	Glycosyl transferase, family 2
L2Z41_02125	COG0438	transferase activity, transferring glycosyl groups
L2Z41_02190	COG0625	glutathione transferase activity
L2Z41_02195	COG0583	DNA-binding transcription factor activity
L2Z41_02200	COG1960	acyl-CoA dehydrogenase activity
L2Z41_02205	COG1960	acyl-CoA dehydrogenase activity
L2Z41_02215	COG2205	protein histidine kinase activity
L2Z41_02220	COG0745	RESPONSE REGULATOR receiver
L2Z41_02225	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z41_02245	COG2096	Adenosyltransferase
L2Z41_02295	COG0285	dihydrofolate synthase activity
L2Z41_02315	COG0450	alkyl hydroperoxide reductase
L2Z41_02330	COG0477	Major facilitator Superfamily
L2Z41_02335	COG1272	protein, Hemolysin III
L2Z41_02365	COG0183	Belongs to the thiolase family
L2Z41_02370	COG2207	Transcriptional regulator
L2Z41_02390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z41_02410	COG0183	Belongs to the thiolase family
L2Z41_02420	COG2885	chlorophyll binding
L2Z41_02420	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z41_02430	COG1690	Belongs to the RtcB family
L2Z41_02435	COG0833	amino acid
L2Z41_02445	COG2233	PERMEase
L2Z41_02450	COG1217	gtp-binding protein TYPA
L2Z41_02475	COG2094	Belongs to the DNA glycosylase MPG family
L2Z41_02495	COG1902	pentaerythritol trinitrate reductase activity
L2Z41_02510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z41_02515	COG0354	folic acid binding
L2Z41_02525	COG3189	MarR family transcriptional regulator
L2Z41_02530	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z41_02535	COG3422	double-strand break repair
L2Z41_02575	COG0840	transmembrane signaling receptor activity
L2Z41_02595	COG5510	response to toxic substance
L2Z41_02605	COG2832	Protein of unknown function (DUF454)
L2Z41_02610	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z41_02650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z41_02660	COG1289	transmembrane transporter activity
L2Z41_02665	COG2814	Major facilitator Superfamily
L2Z41_02685	COG1115	amino acid carrier protein
L2Z41_02690	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z41_02695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z41_02700	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z41_02740	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z41_02750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z41_02755	COG1077	Cell shape determining protein MreB Mrl
L2Z41_02760	COG1792	Involved in formation and maintenance of cell shape
L2Z41_02765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z41_02770	COG0424	maF-like protein
L2Z41_02775	COG1530	ribonuclease E activity
L2Z41_02785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z41_02795	COG0560	Phosphoserine phosphatase
L2Z41_02805	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z41_02830	COG2207	Transcriptional regulator
L2Z41_02850	COG1113	amino acid transport
L2Z41_02855	COG2828	Protein conserved in bacteria
L2Z41_02860	COG0142	geranyltranstransferase activity
L2Z41_02865	COG2315	Protein conserved in bacteria
L2Z41_02880	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z41_02900	COG2194	sulfuric ester hydrolase activity
L2Z41_02905	COG0745	RESPONSE REGULATOR receiver
L2Z41_02910	COG0642	Histidine kinase
L2Z41_02920	COG0004	ammonium transporteR
L2Z41_02925	COG0583	DNA-binding transcription factor activity
L2Z41_02945	COG0525	valine-tRNA ligase activity
L2Z41_02955	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_02965	COG0393	Putative heavy-metal-binding
L2Z41_02970	COG0393	Putative heavy-metal-binding
L2Z41_02975	COG1538	Outer membrane efflux protein
L2Z41_02985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z41_02990	COG0671	phosphoesterase, PA-phosphatase related
L2Z41_03020	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z41_03035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z41_03035	COG1648	precorrin-2 dehydrogenase activity
L2Z41_03040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z41_03045	COG1733	regulation of RNA biosynthetic process
L2Z41_03055	COG0531	amino acid
L2Z41_03070	COG0321	lipoyl(octanoyl) transferase activity
L2Z41_03075	COG2921	Belongs to the UPF0250 family
L2Z41_03115	COG2009	succinate dehydrogenase
L2Z41_03120	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z41_03125	COG1053	succinate dehydrogenase
L2Z41_03130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z41_03155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z41_03175	COG2354	Protein conserved in bacteria
L2Z41_03180	COG2321	neutral zinc metallopeptidase
L2Z41_03200	COG2843	Capsule synthesis protein
L2Z41_03215	COG0589	response to stress
L2Z41_03235	COG0505	Belongs to the CarA family
L2Z41_03260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z41_03265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z41_03315	COG0477	Major facilitator Superfamily
L2Z41_03320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z41_03335	COG1597	lipid kinase activity
L2Z41_03340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z41_03370	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z41_03390	COG0741	lytic transglycosylase activity
L2Z41_03410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z41_03425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z41_03455	COG0778	Nitroreductase
L2Z41_03470	COG1929	Belongs to the glycerate kinase type-1 family
L2Z41_03475	COG0243	molybdopterin cofactor binding
L2Z41_03480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z41_03485	COG3339	Conserved Protein
L2Z41_03495	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z41_03510	COG1113	amino acid transport
L2Z41_03520	COG0019	diaminopimelate decarboxylase activity
L2Z41_03530	COG1280	lysine exporter protein (LysE YggA)
L2Z41_03535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z41_03565	COG0463	Glycosyl transferase, family 2
L2Z41_03585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z41_03620	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z41_03625	COG1136	(ABC) transporter
L2Z41_03630	COG2333	competence protein COMEC
L2Z41_03630	COG0658	competence protein
L2Z41_03640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z41_03640	COG0616	signal peptide processing
L2Z41_03645	COG0596	Alpha beta hydrolase
L2Z41_03650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z41_03660	COG0628	permease
L2Z41_03700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z41_03720	COG0823	Involved in the tonB-independent uptake of proteins
L2Z41_03740	COG0824	Thioesterase
L2Z41_03745	COG1473	amidohydrolase
L2Z41_03765	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z41_03765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z41_03770	COG2814	Major facilitator Superfamily
L2Z41_03780	COG1024	Enoyl-CoA hydratase
L2Z41_03785	COG1051	belongs to the nudix hydrolase family
L2Z41_03785	COG1056	cytidyltransferase-related domain
L2Z41_03795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z41_03810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z41_03825	COG4625	pathogenesis
L2Z41_03830	COG0583	DNA-binding transcription factor activity
L2Z41_03835	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z41_03840	COG4208	sulfate ABC transporter
L2Z41_03845	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z41_03855	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z41_03860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z41_03865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z41_03885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z41_03900	COG0681	Belongs to the peptidase S26 family
L2Z41_03915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z41_03925	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z41_03930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z41_03940	COG4221	oxidoreductase activity
L2Z41_03970	COG0436	Aminotransferase
L2Z41_03990	COG0556	nucleotide-excision repair
L2Z41_04045	COG2070	2-Nitropropane dioxygenase
L2Z41_04075	COG1215	transferase activity, transferring glycosyl groups
L2Z41_04090	COG0415	Belongs to the DNA photolyase family
L2Z41_04100	COG1252	NADH dehydrogenase
L2Z41_04105	COG1686	Belongs to the peptidase S11 family
L2Z41_04120	COG1187	pseudouridine synthase activity
L2Z41_04145	COG0477	Major facilitator Superfamily
L2Z41_04150	COG0583	DNA-binding transcription factor activity
L2Z41_04155	COG1823	symporter activity
L2Z41_04175	COG0612	Peptidase, M16
L2Z41_04200	COG0352	thiamine-phosphate diphosphorylase activity
L2Z41_04235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z41_04250	COG1309	transcriptional regulator
L2Z41_04260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z41_04265	COG0076	glutamate decarboxylase activity
L2Z41_04275	COG1522	sequence-specific DNA binding
L2Z41_04280	COG3961	Belongs to the TPP enzyme family
L2Z41_04285	COG1113	amino acid transport
L2Z41_04290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z41_04295	COG0573	inorganic phosphate transmembrane transporter activity
L2Z41_04305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z41_04310	COG0616	signal peptide processing
L2Z41_04320	COG3328	transposase activity
L2Z41_04350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z41_04355	COG1686	Belongs to the peptidase S11 family
L2Z41_04380	COG0583	DNA-binding transcription factor activity
L2Z41_04385	COG1067	ATP-dependent peptidase activity
L2Z41_04430	COG1966	Carbon starvation protein
L2Z41_04435	COG2879	small protein
L2Z41_04470	COG2508	Transcriptional regulator
L2Z41_04470	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z41_04490	COG1113	amino acid transport
L2Z41_04495	COG0583	DNA-binding transcription factor activity
L2Z41_04500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z41_04505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z41_04515	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_04525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z41_04530	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z41_04530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z41_04565	COG2814	Major facilitator Superfamily
L2Z41_04570	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z41_04580	COG1309	transcriptional regulator
L2Z41_04600	COG1741	Belongs to the pirin family
L2Z41_04610	COG2964	Protein conserved in bacteria
L2Z41_04625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z41_04630	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z41_04635	COG4605	iron ion homeostasis
L2Z41_04640	COG4604	ABC transporter, ATP-binding protein
L2Z41_04645	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z41_04650	COG4774	siderophore transport
L2Z41_04660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z41_04665	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z41_04670	COG3433	isochorismatase activity
L2Z41_04670	COG1535	isochorismatase
L2Z41_04685	COG1132	(ABC) transporter
L2Z41_04690	COG1132	(ABC) transporter
L2Z41_04695	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z41_04705	COG1169	isochorismate synthase
L2Z41_04720	COG3739	integral membrane protein
L2Z41_04745	COG0302	gtp cyclohydrolase
L2Z41_04755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z41_04785	COG0308	aminopeptidase N
L2Z41_04790	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z41_04980	COG5410	chromosome segregation
L2Z41_05170	COG0582	viral genome integration into host DNA
L2Z41_05185	COG0174	glutamine synthetase
L2Z41_05195	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z41_05230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z41_05235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z41_05240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z41_05260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z41_05265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z41_05270	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z41_05285	COG1960	acyl-CoA dehydrogenase activity
L2Z41_05290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z41_05295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z41_05305	COG2223	nitrite transmembrane transporter activity
L2Z41_05315	COG0024	Methionine aminopeptidase
L2Z41_05320	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z41_05335	COG2207	Transcriptional regulator
L2Z41_05360	COG2951	lytic endotransglycosylase activity
L2Z41_05365	COG0772	Belongs to the SEDS family
L2Z41_05380	COG0842	Transport permease protein
L2Z41_05385	COG1131	(ABC) transporter
L2Z41_05430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z41_05445	COG4215	(ABC) transporter
L2Z41_05450	COG4160	amino acid transport
L2Z41_05455	COG4598	ABC transporter
L2Z41_05465	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z41_05470	COG0826	peptidase U32
L2Z41_05475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z41_05490	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z41_05500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z41_05515	COG0642	Histidine kinase
L2Z41_05525	COG0494	nUDIX hydrolase
L2Z41_05535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z41_05540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z41_05545	COG3139	Protein of unknown function (DUF1315)
L2Z41_05550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z41_05555	COG1301	dicarboxylic acid transport
L2Z41_05560	COG1960	acyl-CoA dehydrogenase activity
L2Z41_05565	COG2819	hydrolase of the alpha beta superfamily
L2Z41_05575	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z41_05585	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z41_05590	COG1234	tRNA 3'-trailer cleavage
L2Z41_05620	COG2363	Small membrane protein
L2Z41_05645	COG0513	Belongs to the DEAD box helicase family
L2Z41_05655	COG0778	Nitroreductase
L2Z41_05685	COG1286	toxin biosynthetic process
L2Z41_05710	COG4783	chaperone-mediated protein folding
L2Z41_05715	COG1610	YqeY-like protein
L2Z41_05815	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z41_05840	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z41_05845	COG0786	glutamate:sodium symporter activity
L2Z41_05855	COG2186	Transcriptional regulator
L2Z41_05905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z41_05910	COG2011	ABC-type metal ion transport system permease component
L2Z41_05915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z41_05920	COG1464	Belongs to the NlpA lipoprotein family
L2Z41_05925	COG0151	Belongs to the GarS family
L2Z41_05930	COG0138	bifunctional purine biosynthesis protein purh
L2Z41_05935	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z41_05965	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z41_05975	COG1305	Transglutaminase-like
L2Z41_05985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z41_05990	COG0305	Participates in initiation and elongation during chromosome replication
L2Z41_06015	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z41_06025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z41_06030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z41_06055	COG0726	polysaccharide deacetylase
L2Z41_06055	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z41_06060	COG1215	transferase activity, transferring glycosyl groups
L2Z41_06065	COG3658	cytochrome
L2Z41_06075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z41_06090	COG0583	DNA-binding transcription factor activity
L2Z41_06110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z41_06115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z41_06130	COG1960	acyl-CoA dehydrogenase activity
L2Z41_06135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z41_06140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z41_06165	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z41_06170	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z41_06180	COG2205	protein histidine kinase activity
L2Z41_06185	COG0745	RESPONSE REGULATOR receiver
L2Z41_06190	COG0174	glutamine synthetase
L2Z41_06210	COG0729	surface antigen
L2Z41_06235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z41_06240	COG2814	Major facilitator Superfamily
L2Z41_06255	COG0583	DNA-binding transcription factor activity
L2Z41_06270	COG1187	pseudouridine synthase activity
L2Z41_06290	COG0802	atpase or kinase
L2Z41_06295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z41_06305	COG1923	regulation of RNA biosynthetic process
L2Z41_06310	COG0697	spore germination
L2Z41_06325	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z41_06335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z41_06340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z41_06340	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z41_06345	COG4302	ethanolamine ammonia-lyase activity
L2Z41_06350	COG4303	Ethanolamine ammonia lyase large subunit
L2Z41_06355	COG0531	amino acid
L2Z41_06375	COG1454	alcohol dehydrogenase
L2Z41_06380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z41_06390	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z41_06410	COG0308	aminopeptidase N
L2Z41_06440	COG1605	Chorismate mutase
L2Z41_06460	COG1309	transcriptional regulator
L2Z41_06470	COG0668	transmembrane transport
L2Z41_06505	COG4773	Receptor
L2Z41_06525	COG0488	(ABC) transporter
L2Z41_06530	COG0589	response to stress
L2Z41_06555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z41_06565	COG3135	benzoate transporter
L2Z41_06570	COG1522	sequence-specific DNA binding
L2Z41_06580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z41_06585	COG0583	DNA-binding transcription factor activity
L2Z41_06595	COG0183	Belongs to the thiolase family
L2Z41_06605	COG2030	dehydratase
L2Z41_06610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z41_06625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z41_06635	COG0824	Thioesterase
L2Z41_06640	COG1454	alcohol dehydrogenase
L2Z41_06650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z41_06670	COG0069	glutamate synthase activity
L2Z41_06875	COG5410	chromosome segregation
L2Z41_06880	COG3567	Phage-associated protein, HI1409 family
L2Z41_06895	COG3566	protein conserved in bacteria
L2Z41_07025	COG2814	Major facilitator Superfamily
L2Z41_07040	COG0511	ligase activity, forming carbon-carbon bonds
L2Z41_07060	COG1116	anion transmembrane transporter activity
L2Z41_07060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z41_07065	COG0745	RESPONSE REGULATOR receiver
L2Z41_07075	COG2146	nitrite reductase [NAD(P)H] activity
L2Z41_07075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z41_07080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z41_07085	COG0243	molybdopterin cofactor binding
L2Z41_07095	COG0243	molybdopterin cofactor binding
L2Z41_07100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z41_07115	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z41_07115	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z41_07120	COG0303	'Molybdopterin
L2Z41_07130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z41_07135	COG0697	spore germination
L2Z41_07155	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z41_07160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z41_07215	COG2204	response regulator
L2Z41_07220	COG3852	Histidine kinase
L2Z41_07240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z41_07245	COG0575	Belongs to the CDS family
L2Z41_07280	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z41_07295	COG2137	regulation of response to DNA damage stimulus
L2Z41_07305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z41_07310	COG1011	Hydrolase
L2Z41_07335	COG1522	sequence-specific DNA binding
L2Z41_07345	COG1113	amino acid transport
L2Z41_07365	COG0659	secondary active sulfate transmembrane transporter activity
L2Z41_07370	COG2135	peptidase activity
L2Z41_07385	COG5001	Diguanylate cyclase
L2Z41_07385	COG3300	MHYT domain
L2Z41_07405	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z41_07405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z41_07405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z41_07410	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z41_07415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z41_07415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z41_07445	COG0024	Methionine aminopeptidase
L2Z41_07450	COG0583	DNA-binding transcription factor activity
L2Z41_07460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z41_07465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z41_07470	COG0517	IMP dehydrogenase activity
L2Z41_07470	COG0516	GMP reductase activity
L2Z41_07495	COG0552	protein localization to endoplasmic reticulum
L2Z41_07505	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z41_07520	COG4890	Cyd operon protein YbgT
L2Z41_07525	COG1294	oxidase, subunit
L2Z41_07540	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z41_07550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z41_07560	COG4774	siderophore transport
L2Z41_07575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z41_07580	COG0569	domain protein
L2Z41_07585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z41_07615	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z41_07620	COG0542	response to heat
L2Z41_07645	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z41_07645	COG1902	pentaerythritol trinitrate reductase activity
L2Z41_07690	COG2323	membrane
L2Z41_07695	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z41_07705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z41_07710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z41_07715	COG0183	Belongs to the thiolase family
L2Z41_07720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z41_07725	COG0596	Alpha beta hydrolase
L2Z41_07730	COG2271	Major facilitator Superfamily
L2Z41_07735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z41_07740	COG3485	protocatechuate 3,4-dioxygenase
L2Z41_07745	COG3485	protocatechuate 3,4-dioxygenase
L2Z41_07750	COG0710	3-dehydroquinate dehydratase activity
L2Z41_07755	COG3420	alginic acid biosynthetic process
L2Z41_07760	COG3659	wide pore channel activity
L2Z41_07765	COG4993	Dehydrogenase
L2Z41_07775	COG2391	methyltransferase activity
L2Z41_07790	COG1414	Transcriptional regulator
L2Z41_07795	COG0583	DNA-binding transcription factor activity
L2Z41_07800	COG1960	acyl-CoA dehydrogenase activity
L2Z41_07825	COG2814	Major facilitator Superfamily
L2Z41_07835	COG0154	amidase activity
L2Z41_07855	COG4638	Rieske (2fe-2S)
L2Z41_07865	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_07875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z41_07885	COG3733	amine oxidase
L2Z41_07895	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_07905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z41_07910	COG0183	Belongs to the thiolase family
L2Z41_07915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z41_07920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z41_07930	COG4829	muconolactone delta-isomerase
L2Z41_07935	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z41_07940	COG0583	DNA-binding transcription factor activity
L2Z41_07950	COG2186	Transcriptional regulator
L2Z41_07970	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_07990	COG1960	acyl-CoA dehydrogenase activity
L2Z41_07995	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_08010	COG3162	membrane
L2Z41_08025	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_08040	COG0753	catalase activity
L2Z41_08060	COG1846	Transcriptional regulator
L2Z41_08065	COG1902	pentaerythritol trinitrate reductase activity
L2Z41_08065	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z41_08075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z41_08105	COG1309	transcriptional regulator
L2Z41_08115	COG1335	isochorismatase
L2Z41_08120	COG0583	DNA-binding transcription factor activity
L2Z41_08130	COG0475	glutathione-regulated potassium exporter activity
L2Z41_08130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z41_08140	COG1473	amidohydrolase
L2Z41_08150	COG2831	hemolysin activation secretion protein
L2Z41_08155	COG3210	domain, Protein
L2Z41_08185	COG2188	Transcriptional regulator
L2Z41_08200	COG0583	DNA-binding transcription factor activity
L2Z41_08230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z41_08260	COG1566	PFAM secretion protein HlyD family protein
L2Z41_08275	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_08280	COG0129	dihydroxy-acid dehydratase activity
L2Z41_08290	COG0583	DNA-binding transcription factor activity
L2Z41_08295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z41_08305	COG2084	Dehydrogenase
L2Z41_08310	COG2207	Transcriptional regulator
L2Z41_08325	COG1064	alcohol dehydrogenase
L2Z41_08335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z41_08340	COG1120	ATPase activity
L2Z41_08360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z41_08480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z41_08530	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_08545	COG2207	Transcriptional regulator
L2Z41_08555	COG2205	protein histidine kinase activity
L2Z41_08560	COG0745	RESPONSE REGULATOR receiver
L2Z41_08565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z41_08570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z41_08575	COG1538	Outer membrane efflux protein
L2Z41_08585	COG2072	flavoprotein involved in K transport
L2Z41_08605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z41_08625	COG3539	Fimbrial protein
L2Z41_08635	COG0477	Major facilitator Superfamily
L2Z41_08655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z41_08660	COG4521	taurine ABC transporter
L2Z41_08675	COG2188	Transcriptional regulator
L2Z41_08685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z41_08690	COG1733	regulation of RNA biosynthetic process
L2Z41_08695	COG2207	Transcriptional regulator
L2Z41_08695	COG3708	Transcriptional regulator
L2Z41_08710	COG0730	response to heat
L2Z41_08725	COG3453	Protein conserved in bacteria
L2Z41_08725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z41_08735	COG3781	membrane
L2Z41_08740	COG1063	alcohol dehydrogenase
L2Z41_08750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z41_08755	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z41_08760	COG0022	dehydrogenase e1 component
L2Z41_08765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z41_08770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z41_08785	COG3706	GGDEF domain
L2Z41_08800	COG0133	tryptophan synthase activity
L2Z41_08810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z41_08845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z41_08870	COG2226	methyltransferase
L2Z41_08925	COG0842	Transport permease protein
L2Z41_08930	COG0842	Transport permease protein
L2Z41_08935	COG1131	(ABC) transporter
L2Z41_08950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z41_08955	COG4773	Receptor
L2Z41_08975	COG0730	response to heat
L2Z41_08980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z41_09000	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z41_09015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z41_09055	COG4264	IucA IucC family
L2Z41_09060	COG4264	IucA IucC family
L2Z41_09080	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z41_09095	COG1960	acyl-CoA dehydrogenase activity
L2Z41_09100	COG1960	acyl-CoA dehydrogenase activity
L2Z41_09105	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z41_09110	COG2207	Transcriptional regulator
L2Z41_09115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z41_09120	COG0776	regulation of translation
L2Z41_09145	COG0822	iron-sulfur transferase activity
L2Z41_09150	COG0316	Belongs to the HesB IscA family
L2Z41_09180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z41_09200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z41_09205	COG0702	epimerase
L2Z41_09240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z41_09250	COG0339	signal peptide processing
L2Z41_09300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z41_09305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z41_09345	COG0776	regulation of translation
L2Z41_09410	COG0084	hydrolase, TatD family'
L2Z41_09430	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z41_09435	COG1132	(ABC) transporter
L2Z41_09445	COG0811	peptide transport
L2Z41_09450	COG1475	DNA binding
L2Z41_09455	COG1192	Involved in chromosome partitioning
L2Z41_09465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z41_09480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z41_09485	COG0191	fructose-bisphosphate aldolase activity
L2Z41_09505	COG0424	maF-like protein
L2Z41_09510	COG2850	peptidyl-arginine hydroxylation
L2Z41_09520	COG0640	Transcriptional regulator
L2Z41_09535	COG3619	membrane
L2Z41_09540	COG3122	Protein conserved in bacteria
L2Z41_09545	COG1132	(ABC) transporter
L2Z41_09565	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z41_09570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z41_09580	COG0506	proline dehydrogenase activity
L2Z41_09580	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z41_09580	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z41_09585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z41_09600	COG3698	Phosphodiester glycosidase
L2Z41_09610	COG2353	YceI-like domain
L2Z41_09620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z41_09665	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z41_09665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z41_09690	COG3539	Fimbrial protein
L2Z41_09695	COG3121	Chaperone
L2Z41_09720	COG0697	spore germination
L2Z41_09730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z41_09740	COG0583	DNA-binding transcription factor activity
L2Z41_09760	COG1309	transcriptional regulator
L2Z41_09775	COG1522	sequence-specific DNA binding
L2Z41_09785	COG1126	abc transporter atp-binding protein
L2Z41_09790	COG0765	amino acid transport
L2Z41_09795	COG0765	amino acid transport
L2Z41_09825	COG1464	Belongs to the NlpA lipoprotein family
L2Z41_09835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z41_09840	COG2011	ABC-type metal ion transport system permease component
L2Z41_09845	COG0012	GTP binding
L2Z41_09870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z41_09910	COG0386	Belongs to the glutathione peroxidase family
L2Z41_09920	COG0436	Aminotransferase
L2Z41_09960	COG3634	alkyl hydroperoxide reductase activity
L2Z41_09975	COG0583	DNA-binding transcription factor activity
L2Z41_09980	COG0798	PFAM Bile acid sodium symporter
L2Z41_09985	COG0640	Transcriptional regulator
L2Z41_10000	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z41_10010	COG0583	DNA-binding transcription factor activity
L2Z41_10020	COG1953	Uracil, thiamine, allantoin
L2Z41_10030	COG2175	clavaminate synthase activity
L2Z41_10035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z41_10040	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z41_10045	COG4521	taurine ABC transporter
L2Z41_10055	COG0477	Major facilitator Superfamily
L2Z41_10075	COG1271	oxidase subunit
L2Z41_10080	COG1294	oxidase, subunit
L2Z41_10090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z41_10110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z41_10130	COG3052	prosthetic group binding
L2Z41_10135	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z41_10145	COG2814	Major facilitator Superfamily
L2Z41_10165	COG1346	cytolysis
L2Z41_10175	COG0583	DNA-binding transcription factor activity
L2Z41_10180	COG0625	glutathione transferase activity
L2Z41_10185	COG0625	glutathione transferase activity
L2Z41_10190	COG0583	DNA-binding transcription factor activity
L2Z41_10205	COG1045	serine acetyltransferase
L2Z41_10210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z41_10215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z41_10225	COG1280	lysine exporter protein (LysE YggA)
L2Z41_10240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z41_10245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z41_10250	COG1126	abc transporter atp-binding protein
L2Z41_10255	COG0765	amino acid transport
L2Z41_10260	COG0765	amino acid transport
L2Z41_10280	COG0784	Response regulator, receiver
L2Z41_10280	COG2205	protein histidine kinase activity
L2Z41_10300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z41_10320	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_10370	COG0583	DNA-binding transcription factor activity
L2Z41_10390	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z41_10395	COG1309	transcriptional regulator
L2Z41_10400	COG1960	acyl-CoA dehydrogenase activity
L2Z41_10405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z41_10410	COG1024	Enoyl-CoA hydratase
L2Z41_10415	COG4770	biotin carboxylase activity
L2Z41_10425	COG0583	DNA-binding transcription factor activity
L2Z41_10440	COG1960	acyl-CoA dehydrogenase activity
L2Z41_10450	COG2814	Major facilitator Superfamily
L2Z41_10460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z41_10465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z41_10470	COG2814	Major facilitator Superfamily
L2Z41_10475	COG1960	acyl-CoA dehydrogenase activity
L2Z41_10480	COG1024	Enoyl-CoA hydratase
L2Z41_10485	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_10490	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z41_10495	COG0183	Belongs to the thiolase family
L2Z41_10505	COG2814	Major facilitator Superfamily
L2Z41_10515	COG1024	Enoyl-CoA hydratase
L2Z41_10530	COG1960	acyl-CoA dehydrogenase activity
L2Z41_10535	COG2814	Major facilitator Superfamily
L2Z41_10540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z41_10545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z41_10560	COG3842	ATPase activity
L2Z41_10565	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z41_10575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z41_10580	COG1414	Transcriptional regulator
L2Z41_10590	COG0583	DNA-binding transcription factor activity
L2Z41_10595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z41_10600	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_10610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z41_10620	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_10625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z41_10630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z41_10635	COG2267	carboxylic ester hydrolase activity
L2Z41_10655	COG3038	cytochrome b561
L2Z41_10660	COG0753	catalase activity
L2Z41_10690	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z41_10700	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z41_10705	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z41_10710	COG0183	Belongs to the thiolase family
L2Z41_10715	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z41_10720	COG1024	Enoyl-CoA hydratase
L2Z41_10725	COG1024	Enoyl-CoA hydratase
L2Z41_10730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z41_10735	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z41_10740	COG3396	Phenylacetate-CoA oxygenase
L2Z41_10745	COG3460	Phenylacetate-CoA oxygenase
L2Z41_10750	COG3396	Phenylacetate-CoA oxygenase
L2Z41_10755	COG2030	dehydratase
L2Z41_10755	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_10760	COG1760	l-serine dehydratase
L2Z41_10765	COG0531	amino acid
L2Z41_10770	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_10785	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z41_10795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z41_10815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z41_10825	COG0789	Transcriptional regulator
L2Z41_10840	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z41_10855	COG2807	transmembrane transport
L2Z41_10860	COG0590	tRNA wobble adenosine to inosine editing
L2Z41_10980	COG1116	anion transmembrane transporter activity
L2Z41_10985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z41_10995	COG0864	Transcriptional regulator
L2Z41_11015	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z41_11020	COG0439	Biotin carboxylase
L2Z41_11035	COG1063	alcohol dehydrogenase
L2Z41_11045	COG1309	transcriptional regulator
L2Z41_11065	COG0038	chloride channel
L2Z41_11070	COG4770	biotin carboxylase activity
L2Z41_11090	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z41_11095	COG0583	DNA-binding transcription factor activity
L2Z41_11145	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z41_11165	COG2814	Major facilitator Superfamily
L2Z41_11180	COG1560	Kdo2-lipid A biosynthetic process
L2Z41_11190	COG5006	permease, DMT superfamily
L2Z41_11195	COG1522	sequence-specific DNA binding
L2Z41_11210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z41_11220	COG4122	O-methyltransferase activity
L2Z41_11250	COG1538	Outer membrane efflux protein
L2Z41_11255	COG1137	ATPase activity
L2Z41_11260	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z41_11270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z41_11275	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z41_11275	COG0517	IMP dehydrogenase activity
L2Z41_11310	COG2814	Major facilitator Superfamily
L2Z41_11345	COG1278	Cold shock
L2Z41_11350	COG1280	lysine exporter protein (LysE YggA)
L2Z41_11380	COG1570	exodeoxyribonuclease VII activity
L2Z41_11430	COG0583	DNA-binding transcription factor activity
L2Z41_11440	COG4638	Rieske (2fe-2S)
L2Z41_11445	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z41_11450	COG0633	Ferredoxin
L2Z41_11450	COG0543	2 iron, 2 sulfur cluster binding
L2Z41_11455	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_11460	COG3135	benzoate transporter
L2Z41_11465	COG2814	Major facilitator Superfamily
L2Z41_11480	COG1643	Atp-dependent helicase
L2Z41_11485	COG0450	alkyl hydroperoxide reductase
L2Z41_11495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z41_11505	COG3634	alkyl hydroperoxide reductase activity
L2Z41_11525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z41_11530	COG0625	glutathione transferase activity
L2Z41_11540	COG2885	chlorophyll binding
L2Z41_11575	COG0542	response to heat
L2Z41_11590	COG1765	OsmC-like protein
L2Z41_11610	COG0667	Aldo Keto reductase
L2Z41_11625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z41_11635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z41_11645	COG0527	aspartate kinase activity
L2Z41_11655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z41_11665	COG3038	cytochrome b561
L2Z41_11670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z41_11675	COG2252	PERMEase
L2Z41_11685	COG2072	flavoprotein involved in K transport
L2Z41_11700	COG1741	Belongs to the pirin family
L2Z41_11705	COG1309	transcriptional regulator
L2Z41_11730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2Z41_11770	COG1902	pentaerythritol trinitrate reductase activity
L2Z41_11770	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z41_11780	COG2203	Gaf domain
L2Z41_11780	COG3706	GGDEF domain
L2Z41_11780	COG4251	negative regulation of phosphorylation
L2Z41_11780	COG5001	Diguanylate cyclase
L2Z41_11790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z41_11810	COG4172	Belongs to the ABC transporter superfamily
L2Z41_11815	COG4239	(ABC) transporter, permease
L2Z41_11820	COG4174	ABC transporter (Permease)
L2Z41_11830	COG0741	lytic transglycosylase activity
L2Z41_11830	COG1388	LysM domain
L2Z41_11830	COG0741	lytic transglycosylase activity
L2Z41_11830	COG1388	LysM domain
L2Z41_11835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z41_11875	COG0583	DNA-binding transcription factor activity
L2Z41_11880	COG1279	arginine transmembrane transporter activity
L2Z41_11900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z41_11905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z41_11910	COG0006	proline dipeptidase activity
L2Z41_11995	COG0739	heme binding
L2Z41_12345	COG3384	dioxygenase
L2Z41_12355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z41_12360	COG2878	Part of a membrane complex involved in electron transport
L2Z41_12365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z41_12390	COG0768	penicillin binding
L2Z41_12395	COG0742	ribosomal rna small subunit methyltransferase
L2Z41_12410	COG0830	nickel cation binding
L2Z41_12420	COG0804	urea catabolic process
L2Z41_12460	COG1253	flavin adenine dinucleotide binding
L2Z41_12465	COG2851	Citrate transporter
L2Z41_12520	COG1773	rubredoxin
L2Z41_12525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z41_12535	COG0583	DNA-binding transcription factor activity
L2Z41_12560	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z41_12565	COG4181	ATPase activity
L2Z41_12610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z41_12630	COG0306	phosphate transporter
L2Z41_12640	COG3958	Transketolase
L2Z41_12645	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z41_12650	COG2271	Major facilitator Superfamily
L2Z41_12655	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_12660	COG0583	DNA-binding transcription factor activity
L2Z41_12675	COG2223	nitrite transmembrane transporter activity
L2Z41_12680	COG2207	Transcriptional regulator
L2Z41_12685	COG2066	Belongs to the glutaminase family
L2Z41_12690	COG0242	peptide deformylase activity
L2Z41_12695	COG0477	Major facilitator Superfamily
L2Z41_12705	COG0028	Belongs to the TPP enzyme family
L2Z41_12720	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_12725	COG2267	carboxylic ester hydrolase activity
L2Z41_12735	COG2271	Major facilitator Superfamily
L2Z41_12740	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z41_12750	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_12770	COG1414	Transcriptional regulator
L2Z41_12785	COG1024	Enoyl-CoA hydratase
L2Z41_12795	COG1215	transferase activity, transferring glycosyl groups
L2Z41_12800	COG0726	polysaccharide deacetylase
L2Z41_12800	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z41_12810	COG4681	YaeQ
L2Z41_12820	COG0523	cobalamin synthesis protein
L2Z41_12830	COG1607	acyl-coa hydrolase
L2Z41_12840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z41_12845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z41_12850	COG1309	transcriptional regulator
L2Z41_12875	COG2040	homocysteine
L2Z41_12880	COG0531	amino acid
L2Z41_12935	COG1595	DNA-templated transcription, initiation
L2Z41_12945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z41_12950	COG0477	Major facilitator Superfamily
L2Z41_12970	COG0084	hydrolase, TatD family'
L2Z41_13005	COG0629	single-stranded DNA binding
L2Z41_13060	COG0582	viral genome integration into host DNA
L2Z41_13165	COG0592	DNA-directed DNA polymerase activity
L2Z41_13205	COG2026	Addiction module toxin, RelE StbE family
L2Z41_13400	COG1484	DNA-dependent DNA replication
L2Z41_13490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z41_13560	COG0405	Gamma-glutamyltransferase
L2Z41_13565	COG2814	Major facilitator Superfamily
L2Z41_13575	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z41_13590	COG1090	epimerase
L2Z41_13610	COG0420	3'-5' exonuclease activity
L2Z41_13635	COG0735	belongs to the Fur family
L2Z41_13640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z41_13660	COG0121	glutamine amidotransferase
L2Z41_13675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z41_13685	COG0210	DNA helicase
L2Z41_13690	COG2885	chlorophyll binding
L2Z41_13695	COG0204	Acyl-transferase
L2Z41_13710	COG2894	cell division
L2Z41_13735	COG1280	lysine exporter protein (LysE YggA)
L2Z41_13740	COG1674	ftsk spoiiie
L2Z41_13740	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z41_13745	COG0492	ferredoxin-NADP+ reductase activity
L2Z41_13750	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z41_13760	COG0456	acetyltransferase
L2Z41_13805	COG1981	membrane
L2Z41_13820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z41_13820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z41_13840	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_13850	COG0657	acetylesterase activity
L2Z41_13860	COG0473	3-isopropylmalate dehydrogenase activity
L2Z41_13865	COG0583	DNA-binding transcription factor activity
L2Z41_13885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z41_13910	COG0564	pseudouridine synthase activity
L2Z41_13920	COG0358	DNA primase activity
L2Z41_13935	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z41_13965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z41_13995	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z41_14005	COG0351	phosphomethylpyrimidine kinase
L2Z41_14005	COG0352	thiamine-phosphate diphosphorylase activity
L2Z41_14005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z41_14010	COG1652	LysM domain
L2Z41_14035	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z41_14040	COG3101	peptidyl-lysine hydroxylation
L2Z41_14045	COG0009	L-threonylcarbamoyladenylate synthase
L2Z41_14050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z41_14055	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z41_14070	COG4106	trans-aconitate 2-methyltransferase activity
L2Z41_14085	COG2226	methyltransferase
L2Z41_14085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z41_14085	COG0596	Alpha beta hydrolase
L2Z41_14090	COG1877	trehalose-phosphatase activity
L2Z41_14095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z41_14100	COG2223	nitrite transmembrane transporter activity
L2Z41_14120	COG1196	nuclear chromosome segregation
L2Z41_14130	COG0730	response to heat
L2Z41_14145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z41_14155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z41_14205	COG0489	protein tyrosine kinase activity
L2Z41_14215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z41_14215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z41_14245	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z41_14250	COG2081	HI0933 family
L2Z41_14260	COG0668	transmembrane transport
L2Z41_14280	COG0583	DNA-binding transcription factor activity
L2Z41_14300	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z41_14305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z41_14335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z41_14375	COG0745	RESPONSE REGULATOR receiver
L2Z41_14395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z41_14405	COG2205	protein histidine kinase activity
L2Z41_14470	COG4993	Dehydrogenase
L2Z41_14495	COG0384	phenazine biosynthesis protein PhzF
L2Z41_14520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z41_14535	COG0583	DNA-binding transcription factor activity
L2Z41_14565	COG0583	DNA-binding transcription factor activity
L2Z41_14580	COG0583	DNA-binding transcription factor activity
L2Z41_14585	COG1053	succinate dehydrogenase
L2Z41_14595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z41_14600	COG2814	Major facilitator Superfamily
L2Z41_14605	COG1960	acyl-CoA dehydrogenase activity
L2Z41_14610	COG0583	DNA-binding transcription factor activity
L2Z41_14615	COG1063	alcohol dehydrogenase
L2Z41_14645	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z41_14650	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z41_14655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z41_14670	COG3667	copper resistance
L2Z41_14675	COG2132	Multicopper oxidase
L2Z41_14685	COG0561	phosphatase activity
L2Z41_14690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z41_14715	COG1214	PFAM Peptidase M22, glycoprotease
L2Z41_14765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z41_14775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z41_14780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z41_14785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z41_14845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z41_14855	COG1846	Transcriptional regulator
L2Z41_14860	COG1764	response to oxidative stress
L2Z41_14910	COG0037	tRNA processing
L2Z41_14920	COG0248	Ppx GppA phosphatase
L2Z41_14950	COG0072	phenylalanine-tRNA ligase activity
L2Z41_14995	COG1238	metal cluster binding
L2Z41_15000	COG0625	glutathione transferase activity
L2Z41_15015	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z41_15020	COG3028	Belongs to the UPF0307 family
L2Z41_15025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z41_15045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z41_15050	COG0617	tRNA 3'-terminal CCA addition
L2Z41_15055	COG1555	photosystem II stabilization
L2Z41_15060	COG3956	TIGRFAM MazG family protein
L2Z41_15070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z41_15090	COG0784	Response regulator, receiver
L2Z41_15090	COG2205	protein histidine kinase activity
L2Z41_15090	COG5002	protein histidine kinase activity
L2Z41_15095	COG1024	Enoyl-CoA hydratase
L2Z41_15100	COG2084	Dehydrogenase
L2Z41_15105	COG3622	Belongs to the hyi family
L2Z41_15135	COG0697	spore germination
L2Z41_15145	COG2814	Major facilitator Superfamily
L2Z41_15150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z41_15160	COG0583	DNA-binding transcription factor activity
L2Z41_15170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z41_15185	COG0084	hydrolase, TatD family'
L2Z41_15200	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z41_15230	COG0440	acetolactate synthase activity
L2Z41_15235	COG0028	Belongs to the TPP enzyme family
L2Z41_15260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z41_15265	COG1136	(ABC) transporter
L2Z41_15265	COG0577	efflux transmembrane transporter activity
L2Z41_15270	COG1538	Outer membrane efflux protein
L2Z41_15285	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z41_15290	COG1162	GTPase activity
L2Z41_15300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z41_15320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z41_15325	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_15365	COG2986	histidine ammonia-lyase
L2Z41_15380	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z41_15390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z41_15435	COG1426	Protein conserved in bacteria
L2Z41_15470	COG0793	Belongs to the peptidase S41A family
L2Z41_15485	COG2267	carboxylic ester hydrolase activity
L2Z41_15495	COG1012	belongs to the aldehyde dehydrogenase family
L2Z41_15500	COG3265	gluconokinase activity
L2Z41_15510	COG0800	Aldolase
L2Z41_15525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z41_15530	COG0280	phosphate acetyltransferase
L2Z41_15530	COG0857	belongs to the CobB CobQ family
L2Z41_15535	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z41_15535	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z41_15555	COG0740	serine-type endopeptidase activity
L2Z41_15565	COG4774	siderophore transport
L2Z41_15575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z41_15585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z41_15585	COG2813	Specifically methylates the guanine in position
L2Z41_15685	COG0788	formyltetrahydrofolate deformylase activity
L2Z41_15710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z41_15710	COG4651	solute:proton antiporter activity
L2Z41_15730	COG0724	RNA recognition motif
L2Z41_15735	COG0210	DNA helicase
L2Z41_15760	COG1733	regulation of RNA biosynthetic process
L2Z41_15770	COG2900	Belongs to the SlyX family
L2Z41_15775	COG0488	(ABC) transporter
L2Z41_15780	COG1280	lysine exporter protein (LysE YggA)
L2Z41_15785	COG1560	Kdo2-lipid A biosynthetic process
L2Z41_15795	COG1301	dicarboxylic acid transport
L2Z41_15850	COG0473	3-isopropylmalate dehydrogenase activity
L2Z41_15915	COG0583	DNA-binding transcription factor activity
L2Z41_15925	COG0625	glutathione transferase activity
L2Z41_15930	COG2378	regulation of single-species biofilm formation
L2Z41_15935	COG0546	phosphoglycolate phosphatase activity
L2Z41_15945	COG1530	ribonuclease E activity
L2Z41_15950	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z41_15965	COG0583	DNA-binding transcription factor activity
L2Z41_15970	COG4221	oxidoreductase activity
L2Z41_15975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z41_15985	COG0534	Mate efflux family protein
L2Z41_16000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z41_16040	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z41_16045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z41_16060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z41_16070	COG0644	oxidoreductase
L2Z41_16070	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z41_16075	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z41_16080	COG4535	Mg2 and Co2 transporter CorC
L2Z41_16090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z41_16110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z41_16115	COG0475	glutathione-regulated potassium exporter activity
L2Z41_16115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z41_16120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z41_16130	COG0484	heat shock protein binding
L2Z41_16135	COG0789	Transcriptional regulator
L2Z41_16140	COG0598	Magnesium transport protein CorA
L2Z41_16155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z41_16160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z41_16165	COG1074	ATP-dependent DNA helicase activity
L2Z41_16170	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z41_16190	COG2226	methyltransferase
L2Z41_16205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z41_16210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z41_16225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z41_16225	COG2111	Na H antiporter
L2Z41_16230	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z41_16235	COG0651	ATP synthesis coupled electron transport
L2Z41_16240	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z41_16245	COG2212	antiporter activity
L2Z41_16250	COG1320	monovalent cation:proton antiporter activity
L2Z41_16265	COG0195	Participates in both transcription termination and antitermination
L2Z41_16315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z41_16320	COG0237	dephospho-CoA kinase activity
L2Z41_16330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z41_16345	COG0497	DNA recombination
L2Z41_16355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z41_16385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z41_16385	COG2169	Transcriptional regulator
L2Z41_16390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z41_16455	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z41_16470	COG0326	Molecular chaperone. Has ATPase activity
L2Z41_16485	COG2056	Na+-H+ antiporter family
L2Z41_16490	COG0596	Alpha beta hydrolase
L2Z41_16585	COG0546	phosphoglycolate phosphatase activity
L2Z41_16590	COG1716	ATPase activity
L2Z41_16635	COG0181	hydroxymethylbilane synthase activity
L2Z41_16645	COG3275	phosphorelay sensor kinase activity
L2Z41_16665	COG1538	Outer membrane efflux protein
L2Z41_16670	COG0697	spore germination
L2Z41_16695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z41_16700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z41_16705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z41_16710	COG0772	Belongs to the SEDS family
L2Z41_16735	COG4974	Belongs to the 'phage' integrase family
L2Z41_16740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z41_16750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z41_16760	COG2197	response regulator
L2Z41_16775	COG0793	Belongs to the peptidase S41A family
L2Z41_16780	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z41_16785	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z41_16825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z41_16825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z41_16835	COG0004	ammonium transporteR
L2Z41_16840	COG0347	Belongs to the P(II) protein family
L2Z41_16915	COG1061	Type III restriction enzyme res subunit
L2Z41_16920	COG1002	Type II restriction enzyme, methylase subunits
L2Z41_16930	COG0659	secondary active sulfate transmembrane transporter activity
L2Z41_16935	COG0589	response to stress
L2Z41_16980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z41_17000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z41_17015	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z41_17025	COG0477	Major facilitator Superfamily
L2Z41_17030	COG2860	membrane
L2Z41_17040	COG1253	flavin adenine dinucleotide binding
L2Z41_17060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z41_17100	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z41_17110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z41_17180	COG0758	DNA mediated transformation
L2Z41_17190	COG0697	spore germination
L2Z41_17195	COG1309	transcriptional regulator
L2Z41_17210	COG0386	Belongs to the glutathione peroxidase family
L2Z41_17275	COG1121	(ABC) transporter
L2Z41_17280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z41_17285	COG1280	lysine exporter protein (LysE YggA)
L2Z41_17290	COG2837	iron assimilation
L2Z41_17300	COG0281	malic enzyme
L2Z41_17345	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z41_17345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z41_17350	COG4399	Belongs to the UPF0754 family
L2Z41_17355	COG2259	Doxx family
L2Z41_17360	COG0586	Pfam SNARE associated Golgi protein
L2Z41_17375	COG1192	Involved in chromosome partitioning
L2Z41_17385	COG0271	Belongs to the BolA IbaG family
L2Z41_17405	COG2267	carboxylic ester hydrolase activity
L2Z41_17425	COG3321	synthase
L2Z41_17425	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z41_17425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z41_17425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z41_17430	COG1960	acyl-CoA dehydrogenase activity
L2Z41_17440	COG2197	response regulator
L2Z41_17450	COG3916	Acyl-homoserine-lactone synthase
L2Z41_17455	COG0477	Major facilitator Superfamily
L2Z41_17460	COG1024	Enoyl-CoA hydratase
L2Z41_17465	COG1024	Enoyl-CoA hydratase
L2Z41_17470	COG1960	acyl-CoA dehydrogenase activity
L2Z41_17475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z41_17495	COG1113	amino acid transport
L2Z41_17500	COG1113	amino acid transport
L2Z41_17505	COG0251	oxidation-reduction process
L2Z41_17545	COG0564	pseudouridine synthase activity
L2Z41_17605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z41_17620	COG1802	Transcriptional regulator
L2Z41_17630	COG1448	Aminotransferase
L2Z41_17635	COG0277	FAD linked oxidase domain protein
L2Z41_17645	COG2186	Transcriptional regulator
L2Z41_17655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z41_17660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z41_17675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z41_17680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z41_17705	COG0438	transferase activity, transferring glycosyl groups
L2Z41_17735	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z41_17765	COG0728	peptidoglycan biosynthetic process
L2Z41_17770	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z41_17825	COG0546	phosphoglycolate phosphatase activity
L2Z41_17830	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z41_17850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z41_17855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z41_17860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z41_17865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z41_17870	COG1116	anion transmembrane transporter activity
L2Z41_17875	COG1309	transcriptional regulator
L2Z41_17880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z41_17890	COG0196	riboflavin kinase activity
L2Z41_17895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z41_17905	COG1047	Peptidyl-prolyl cis-trans
L2Z41_17945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z41_17950	COG0657	acetylesterase activity
L2Z41_17970	COG0583	DNA-binding transcription factor activity
L2Z41_18000	COG2951	lytic endotransglycosylase activity
L2Z41_18005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z41_18020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z41_18030	COG0671	phosphoesterase, PA-phosphatase related
L2Z41_18035	COG0861	Integral membrane protein TerC family
L2Z41_18045	COG0754	glutathionylspermidine amidase activity
L2Z41_18055	COG0402	S-adenosylhomocysteine deaminase activity
L2Z41_18070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z41_18075	COG1230	cation diffusion facilitator family transporter
L2Z41_18090	COG0706	membrane insertase activity
L2Z41_18115	COG0592	DNA-directed DNA polymerase activity
L2Z41_18125	COG0187	DNA topoisomerase II activity
L2Z41_18135	COG0586	Pfam SNARE associated Golgi protein
L2Z41_18140	COG0488	(ABC) transporter
L2Z41_18170	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z41_18175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z41_18215	COG0733	neurotransmitter:sodium symporter activity
L2Z41_18255	COG2233	PERMEase
L2Z41_18270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z41_18305	COG2814	Major facilitator Superfamily
L2Z41_18310	COG0656	L-ascorbic acid biosynthetic process
L2Z41_18315	COG0583	DNA-binding transcription factor activity
L2Z41_18330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z41_18335	COG1064	alcohol dehydrogenase
L2Z41_18340	COG2818	Glycosylase
L2Z41_18355	COG1194	a g-specific adenine glycosylase
L2Z41_18375	COG2983	Belongs to the UPF0260 family
L2Z41_18380	COG2133	pyrroloquinoline quinone binding
L2Z41_18385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z41_18390	COG2116	formate transmembrane transporter activity
L2Z41_18410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z41_18415	COG1335	isochorismatase
L2Z41_18420	COG0385	Bile acid
L2Z41_18425	COG0534	Mate efflux family protein
L2Z41_18430	COG1683	Conserved Protein
L2Z41_18450	COG0625	glutathione transferase activity
L2Z41_18460	COG1113	amino acid transport
L2Z41_18470	COG0523	cobalamin synthesis protein
L2Z41_18480	COG2188	Transcriptional regulator
L2Z41_18510	COG0010	Belongs to the arginase family
L2Z41_18525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z41_18530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z41_18540	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z41_18545	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z41_18645	COG0534	Mate efflux family protein
L2Z41_18650	COG0436	Aminotransferase
L2Z41_18655	COG2733	membrane
L2Z41_18670	COG2918	glutathione biosynthetic process
L2Z41_18685	COG0791	NLP P60 protein
L2Z41_18685	COG1388	LysM domain
L2Z41_18700	COG3150	esterase