locus-tag	class	description
L2Z04_00010	COG4774	siderophore transport
L2Z04_00020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z04_00030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z04_00030	COG2813	Specifically methylates the guanine in position
L2Z04_00130	COG0788	formyltetrahydrofolate deformylase activity
L2Z04_00155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z04_00155	COG4651	solute:proton antiporter activity
L2Z04_00175	COG0724	RNA recognition motif
L2Z04_00180	COG0210	DNA helicase
L2Z04_00205	COG1733	regulation of RNA biosynthetic process
L2Z04_00215	COG2900	Belongs to the SlyX family
L2Z04_00220	COG0488	(ABC) transporter
L2Z04_00225	COG1280	lysine exporter protein (LysE YggA)
L2Z04_00230	COG1560	Kdo2-lipid A biosynthetic process
L2Z04_00240	COG1301	dicarboxylic acid transport
L2Z04_00295	COG0473	3-isopropylmalate dehydrogenase activity
L2Z04_00360	COG0583	DNA-binding transcription factor activity
L2Z04_00370	COG0625	glutathione transferase activity
L2Z04_00375	COG2378	regulation of single-species biofilm formation
L2Z04_00380	COG0546	phosphoglycolate phosphatase activity
L2Z04_00390	COG1530	ribonuclease E activity
L2Z04_00395	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z04_00410	COG0583	DNA-binding transcription factor activity
L2Z04_00415	COG4221	oxidoreductase activity
L2Z04_00420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z04_00430	COG0534	Mate efflux family protein
L2Z04_00445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z04_00485	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z04_00490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z04_00505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z04_00515	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z04_00515	COG0644	oxidoreductase
L2Z04_00520	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z04_00525	COG4535	Mg2 and Co2 transporter CorC
L2Z04_00535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z04_00555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z04_00560	COG0475	glutathione-regulated potassium exporter activity
L2Z04_00560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z04_00565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z04_00575	COG0484	heat shock protein binding
L2Z04_00580	COG0789	Transcriptional regulator
L2Z04_00585	COG0598	Magnesium transport protein CorA
L2Z04_00600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z04_00605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z04_00610	COG1074	ATP-dependent DNA helicase activity
L2Z04_00615	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z04_00635	COG2226	methyltransferase
L2Z04_00650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z04_00655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z04_00670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z04_00670	COG2111	Na H antiporter
L2Z04_00675	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z04_00680	COG0651	ATP synthesis coupled electron transport
L2Z04_00685	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z04_00690	COG2212	antiporter activity
L2Z04_00695	COG1320	monovalent cation:proton antiporter activity
L2Z04_00710	COG0195	Participates in both transcription termination and antitermination
L2Z04_00765	COG0237	dephospho-CoA kinase activity
L2Z04_00775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z04_00790	COG0497	DNA recombination
L2Z04_00800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z04_00830	COG2169	Transcriptional regulator
L2Z04_00830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z04_00835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z04_00900	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z04_00915	COG0326	Molecular chaperone. Has ATPase activity
L2Z04_00965	COG0596	Alpha beta hydrolase
L2Z04_01070	COG0546	phosphoglycolate phosphatase activity
L2Z04_01075	COG1716	ATPase activity
L2Z04_01120	COG0181	hydroxymethylbilane synthase activity
L2Z04_01130	COG3275	phosphorelay sensor kinase activity
L2Z04_01150	COG1538	Outer membrane efflux protein
L2Z04_01155	COG0697	spore germination
L2Z04_01180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z04_01185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z04_01190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z04_01195	COG0772	Belongs to the SEDS family
L2Z04_01220	COG4974	Belongs to the 'phage' integrase family
L2Z04_01225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z04_01235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z04_01245	COG2197	response regulator
L2Z04_01260	COG0793	Belongs to the peptidase S41A family
L2Z04_01265	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z04_01270	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z04_01310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z04_01310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z04_01320	COG0004	ammonium transporteR
L2Z04_01325	COG0347	Belongs to the P(II) protein family
L2Z04_01385	COG0659	secondary active sulfate transmembrane transporter activity
L2Z04_01390	COG0589	response to stress
L2Z04_01435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z04_01445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z04_01465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z04_01480	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z04_01490	COG0477	Major facilitator Superfamily
L2Z04_01495	COG2860	membrane
L2Z04_01505	COG1253	flavin adenine dinucleotide binding
L2Z04_01515	COG2814	Major facilitator Superfamily
L2Z04_01525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z04_01565	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z04_01575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z04_01645	COG0758	DNA mediated transformation
L2Z04_01655	COG0697	spore germination
L2Z04_01660	COG1309	transcriptional regulator
L2Z04_01675	COG0386	Belongs to the glutathione peroxidase family
L2Z04_01745	COG1121	(ABC) transporter
L2Z04_01750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z04_01755	COG1280	lysine exporter protein (LysE YggA)
L2Z04_01760	COG2837	iron assimilation
L2Z04_01765	COG0281	malic enzyme
L2Z04_01810	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z04_01810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z04_01815	COG4399	Belongs to the UPF0754 family
L2Z04_01820	COG2259	Doxx family
L2Z04_01825	COG0586	Pfam SNARE associated Golgi protein
L2Z04_01840	COG1192	Involved in chromosome partitioning
L2Z04_01850	COG0271	Belongs to the BolA IbaG family
L2Z04_01890	COG3321	synthase
L2Z04_01890	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z04_01890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z04_01890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z04_01895	COG1960	acyl-CoA dehydrogenase activity
L2Z04_01905	COG2197	response regulator
L2Z04_01915	COG3916	Acyl-homoserine-lactone synthase
L2Z04_01920	COG0477	Major facilitator Superfamily
L2Z04_01925	COG1024	Enoyl-CoA hydratase
L2Z04_01930	COG1024	Enoyl-CoA hydratase
L2Z04_01935	COG1960	acyl-CoA dehydrogenase activity
L2Z04_01940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z04_01960	COG1113	amino acid transport
L2Z04_01965	COG1113	amino acid transport
L2Z04_01970	COG0251	oxidation-reduction process
L2Z04_02010	COG0564	pseudouridine synthase activity
L2Z04_02065	COG2801	Transposase and inactivated derivatives
L2Z04_02105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z04_02120	COG1802	Transcriptional regulator
L2Z04_02130	COG1448	Aminotransferase
L2Z04_02135	COG0277	FAD linked oxidase domain protein
L2Z04_02145	COG2186	Transcriptional regulator
L2Z04_02155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z04_02160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z04_02175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z04_02185	COG0110	maltose O-acetyltransferase activity
L2Z04_02190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z04_02220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z04_02225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z04_02230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z04_02235	COG1596	polysaccharide export
L2Z04_02270	COG0728	peptidoglycan biosynthetic process
L2Z04_02275	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z04_02330	COG0546	phosphoglycolate phosphatase activity
L2Z04_02335	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_02355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z04_02360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z04_02365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z04_02370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z04_02375	COG1116	anion transmembrane transporter activity
L2Z04_02380	COG1309	transcriptional regulator
L2Z04_02385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z04_02395	COG0196	riboflavin kinase activity
L2Z04_02400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z04_02410	COG1047	Peptidyl-prolyl cis-trans
L2Z04_02430	COG4372	Transposase
L2Z04_02470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z04_02475	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z04_02480	COG0596	Alpha beta hydrolase
L2Z04_02505	COG0488	(ABC) transporter
L2Z04_02510	COG0586	Pfam SNARE associated Golgi protein
L2Z04_02520	COG0187	DNA topoisomerase II activity
L2Z04_02530	COG0592	DNA-directed DNA polymerase activity
L2Z04_02555	COG0706	membrane insertase activity
L2Z04_02570	COG1230	cation diffusion facilitator family transporter
L2Z04_02575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z04_02590	COG0402	S-adenosylhomocysteine deaminase activity
L2Z04_02600	COG0754	glutathionylspermidine amidase activity
L2Z04_02610	COG0861	Integral membrane protein TerC family
L2Z04_02615	COG0671	phosphoesterase, PA-phosphatase related
L2Z04_02620	COG3328	transposase activity
L2Z04_02630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z04_02645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z04_02650	COG2951	lytic endotransglycosylase activity
L2Z04_02680	COG0583	DNA-binding transcription factor activity
L2Z04_02700	COG0657	acetylesterase activity
L2Z04_02705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z04_02745	COG0733	neurotransmitter:sodium symporter activity
L2Z04_02780	COG0583	DNA-binding transcription factor activity
L2Z04_02785	COG2233	PERMEase
L2Z04_02800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z04_02835	COG2814	Major facilitator Superfamily
L2Z04_02840	COG0656	L-ascorbic acid biosynthetic process
L2Z04_02845	COG0583	DNA-binding transcription factor activity
L2Z04_02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z04_02865	COG1064	alcohol dehydrogenase
L2Z04_02870	COG2818	Glycosylase
L2Z04_02885	COG1194	a g-specific adenine glycosylase
L2Z04_02905	COG2983	Belongs to the UPF0260 family
L2Z04_02910	COG2133	pyrroloquinoline quinone binding
L2Z04_02915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z04_02920	COG2116	formate transmembrane transporter activity
L2Z04_02940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z04_02945	COG1335	isochorismatase
L2Z04_02950	COG0385	Bile acid
L2Z04_02955	COG0534	Mate efflux family protein
L2Z04_02960	COG1683	Conserved Protein
L2Z04_02980	COG0625	glutathione transferase activity
L2Z04_02990	COG1113	amino acid transport
L2Z04_03000	COG0523	cobalamin synthesis protein
L2Z04_03010	COG2188	Transcriptional regulator
L2Z04_03040	COG0010	Belongs to the arginase family
L2Z04_03055	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z04_03060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z04_03070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z04_03075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z04_03180	COG0358	DNA primase activity
L2Z04_03190	COG0564	pseudouridine synthase activity
L2Z04_03215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z04_03235	COG0583	DNA-binding transcription factor activity
L2Z04_03240	COG0473	3-isopropylmalate dehydrogenase activity
L2Z04_03250	COG0657	acetylesterase activity
L2Z04_03260	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_03280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z04_03280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z04_03295	COG1981	membrane
L2Z04_03340	COG0456	acetyltransferase
L2Z04_03350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z04_03355	COG0492	ferredoxin-NADP+ reductase activity
L2Z04_03360	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z04_03360	COG1674	ftsk spoiiie
L2Z04_03365	COG1280	lysine exporter protein (LysE YggA)
L2Z04_03395	COG2894	cell division
L2Z04_03410	COG0204	Acyl-transferase
L2Z04_03415	COG2885	chlorophyll binding
L2Z04_03420	COG0210	DNA helicase
L2Z04_03430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z04_03445	COG0121	glutamine amidotransferase
L2Z04_03465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z04_03470	COG0735	belongs to the Fur family
L2Z04_03495	COG0420	3'-5' exonuclease activity
L2Z04_03515	COG1090	epimerase
L2Z04_03530	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z04_03540	COG2814	Major facilitator Superfamily
L2Z04_03545	COG0405	Gamma-glutamyltransferase
L2Z04_03555	COG0582	viral genome integration into host DNA
L2Z04_03600	COG0629	single-stranded DNA binding
L2Z04_03655	COG0477	Major facilitator Superfamily
L2Z04_03660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z04_03685	COG0531	amino acid
L2Z04_03690	COG2040	homocysteine
L2Z04_03715	COG1309	transcriptional regulator
L2Z04_03720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z04_03725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z04_03735	COG1607	acyl-coa hydrolase
L2Z04_03745	COG0523	cobalamin synthesis protein
L2Z04_03755	COG4681	YaeQ
L2Z04_03765	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z04_03765	COG0726	polysaccharide deacetylase
L2Z04_03770	COG1215	transferase activity, transferring glycosyl groups
L2Z04_03780	COG1024	Enoyl-CoA hydratase
L2Z04_03795	COG1414	Transcriptional regulator
L2Z04_03815	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_03825	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z04_03830	COG2271	Major facilitator Superfamily
L2Z04_03840	COG2267	carboxylic ester hydrolase activity
L2Z04_03845	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_03860	COG0028	Belongs to the TPP enzyme family
L2Z04_03870	COG0477	Major facilitator Superfamily
L2Z04_03875	COG0242	peptide deformylase activity
L2Z04_03880	COG2066	Belongs to the glutaminase family
L2Z04_03885	COG2207	Transcriptional regulator
L2Z04_03890	COG2223	nitrite transmembrane transporter activity
L2Z04_03905	COG0583	DNA-binding transcription factor activity
L2Z04_03910	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_03915	COG2271	Major facilitator Superfamily
L2Z04_03920	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z04_03925	COG3958	Transketolase
L2Z04_03935	COG0306	phosphate transporter
L2Z04_03955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z04_04000	COG4181	ATPase activity
L2Z04_04005	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z04_04030	COG0583	DNA-binding transcription factor activity
L2Z04_04040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z04_04045	COG1773	rubredoxin
L2Z04_04095	COG2851	Citrate transporter
L2Z04_04100	COG1253	flavin adenine dinucleotide binding
L2Z04_04140	COG0804	urea catabolic process
L2Z04_04150	COG0830	nickel cation binding
L2Z04_04165	COG0742	ribosomal rna small subunit methyltransferase
L2Z04_04170	COG0768	penicillin binding
L2Z04_04195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z04_04200	COG2878	Part of a membrane complex involved in electron transport
L2Z04_04205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z04_04215	COG3384	dioxygenase
L2Z04_04245	COG4372	Transposase
L2Z04_04260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z04_04585	COG0739	heme binding
L2Z04_04630	COG2194	sulfuric ester hydrolase activity
L2Z04_04670	COG0006	proline dipeptidase activity
L2Z04_04675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z04_04680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z04_04700	COG1279	arginine transmembrane transporter activity
L2Z04_04705	COG0583	DNA-binding transcription factor activity
L2Z04_04745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z04_04750	COG1388	LysM domain
L2Z04_04750	COG0741	lytic transglycosylase activity
L2Z04_04750	COG0741	lytic transglycosylase activity
L2Z04_04750	COG1388	LysM domain
L2Z04_04760	COG4174	ABC transporter (Permease)
L2Z04_04765	COG4239	(ABC) transporter, permease
L2Z04_04770	COG4172	Belongs to the ABC transporter superfamily
L2Z04_04790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z04_04800	COG3706	GGDEF domain
L2Z04_04800	COG4251	negative regulation of phosphorylation
L2Z04_04800	COG5001	Diguanylate cyclase
L2Z04_04800	COG2203	Gaf domain
L2Z04_04810	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z04_04810	COG1902	pentaerythritol trinitrate reductase activity
L2Z04_04825	COG4269	membrane
L2Z04_04885	COG0789	Transcriptional regulator
L2Z04_04965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2Z04_05040	COG4372	Transposase
L2Z04_05055	COG0534	Mate efflux family protein
L2Z04_05060	COG0436	Aminotransferase
L2Z04_05065	COG2733	membrane
L2Z04_05080	COG2918	glutathione biosynthetic process
L2Z04_05095	COG0791	NLP P60 protein
L2Z04_05095	COG1388	LysM domain
L2Z04_05110	COG3150	esterase
L2Z04_05120	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_05125	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z04_05135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z04_05145	COG2233	PERMEase
L2Z04_05150	COG2351	hydroxyisourate hydrolase activity
L2Z04_05190	COG4372	Transposase
L2Z04_05220	COG1393	Belongs to the ArsC family
L2Z04_05225	COG0708	Exodeoxyribonuclease III
L2Z04_05245	COG0189	ligase activity
L2Z04_05265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z04_05275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z04_05290	COG4942	peptidase
L2Z04_05300	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z04_05310	COG2119	membrane
L2Z04_05315	COG4774	siderophore transport
L2Z04_05320	COG0426	domain, Protein
L2Z04_05320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z04_05345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z04_05365	COG1902	pentaerythritol trinitrate reductase activity
L2Z04_05370	COG1519	Transferase
L2Z04_05375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z04_05380	COG0668	transmembrane transport
L2Z04_05390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z04_05395	COG1335	isochorismatase
L2Z04_05400	COG1522	sequence-specific DNA binding
L2Z04_05405	COG3328	transposase activity
L2Z04_05430	COG2198	Histidine kinase
L2Z04_05430	COG2205	protein histidine kinase activity
L2Z04_05430	COG0784	Response regulator, receiver
L2Z04_05435	COG3162	membrane
L2Z04_05440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z04_05450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z04_05470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z04_05475	COG1309	transcriptional regulator
L2Z04_05495	COG0351	phosphomethylpyrimidine kinase
L2Z04_05495	COG0352	thiamine-phosphate diphosphorylase activity
L2Z04_05495	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z04_05505	COG2814	Major facilitator Superfamily
L2Z04_05520	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z04_05530	COG1113	amino acid transport
L2Z04_05540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z04_05545	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_05555	COG1335	isochorismatase
L2Z04_05595	COG2814	Major facilitator Superfamily
L2Z04_05600	COG0583	DNA-binding transcription factor activity
L2Z04_05620	COG0667	Aldo Keto reductase
L2Z04_05655	COG1733	regulation of RNA biosynthetic process
L2Z04_05660	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z04_05725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z04_05740	COG2329	Antibiotic biosynthesis monooxygenase
L2Z04_05770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z04_05800	COG0427	acetyl-CoA hydrolase
L2Z04_05825	COG0659	secondary active sulfate transmembrane transporter activity
L2Z04_05830	COG4221	oxidoreductase activity
L2Z04_05835	COG2873	o-acetylhomoserine
L2Z04_05840	COG0488	(ABC) transporter
L2Z04_05925	COG0833	amino acid
L2Z04_05970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z04_05975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z04_05990	COG2226	methyltransferase
L2Z04_06040	COG0070	glutamate synthase
L2Z04_06040	COG0069	glutamate synthase activity
L2Z04_06040	COG0067	glutamate synthase
L2Z04_06045	COG0493	'glutamate synthase
L2Z04_06055	COG1704	LemA family
L2Z04_06060	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z04_06080	COG3307	-O-antigen
L2Z04_06100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z04_06115	COG0194	GDP metabolic process
L2Z04_06165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z04_06185	COG5380	lipid catabolic process
L2Z04_06190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z04_06215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z04_06220	COG0277	FAD linked oxidase domain protein
L2Z04_06230	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z04_06235	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z04_06250	COG1289	transmembrane transporter activity
L2Z04_06260	COG0628	permease
L2Z04_06265	COG1192	Involved in chromosome partitioning
L2Z04_06295	COG0833	amino acid
L2Z04_06300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z04_06305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z04_06315	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_06355	COG0583	DNA-binding transcription factor activity
L2Z04_06400	COG0517	IMP dehydrogenase activity
L2Z04_06405	COG1983	PspC domain protein
L2Z04_06415	COG1960	acyl-CoA dehydrogenase activity
L2Z04_06430	COG0408	coproporphyrinogen oxidase activity
L2Z04_06450	COG0513	Belongs to the DEAD box helicase family
L2Z04_06460	COG1127	ABC transporter
L2Z04_06465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z04_06475	COG2854	intermembrane phospholipid transfer
L2Z04_06485	COG0598	Magnesium transport protein CorA
L2Z04_06495	COG0494	nUDIX hydrolase
L2Z04_06500	COG1040	competence protein
L2Z04_06505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z04_06525	COG1946	Acyl-CoA thioesterase
L2Z04_06530	COG1301	dicarboxylic acid transport
L2Z04_06545	COG1959	2 iron, 2 sulfur cluster binding
L2Z04_06550	COG1017	nitric oxide dioxygenase activity
L2Z04_06550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z04_06555	COG0433	COG0433 Predicted ATPase
L2Z04_06560	COG0626	cystathionine gamma-synthase activity
L2Z04_06715	COG1960	acyl-CoA dehydrogenase activity
L2Z04_06720	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z04_06750	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z04_06755	COG0339	signal peptide processing
L2Z04_06760	COG0557	exoribonuclease II activity
L2Z04_06805	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z04_06810	COG2169	Transcriptional regulator
L2Z04_06815	COG0697	spore germination
L2Z04_06820	COG1295	ribonuclease BN
L2Z04_06855	COG1702	phosphate starvation-inducible protein PhoH
L2Z04_06865	COG0739	heme binding
L2Z04_06865	COG0741	lytic transglycosylase activity
L2Z04_06865	COG1196	nuclear chromosome segregation
L2Z04_06895	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z04_06900	COG1183	phosphatidylcholine synthase activity
L2Z04_06945	COG1960	acyl-CoA dehydrogenase activity
L2Z04_06950	COG1309	transcriptional regulator
L2Z04_06965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z04_06970	COG1960	acyl-CoA dehydrogenase activity
L2Z04_06990	COG2969	positive regulation of protein catabolic process
L2Z04_07000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z04_07015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z04_07020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z04_07040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z04_07050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z04_07055	COG1408	metallophosphoesterase
L2Z04_07065	COG2199	diguanylate cyclase activity
L2Z04_07125	COG1607	acyl-coa hydrolase
L2Z04_07155	COG2350	Protein conserved in bacteria
L2Z04_07165	COG0613	PHP domain protein
L2Z04_07170	COG3781	membrane
L2Z04_07180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z04_07185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z04_07195	COG1862	Preprotein translocase
L2Z04_07245	COG2205	protein histidine kinase activity
L2Z04_07250	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z04_07270	COG0726	polysaccharide deacetylase
L2Z04_07275	COG0463	Glycosyl transferase, family 2
L2Z04_07280	COG0438	transferase activity, transferring glycosyl groups
L2Z04_07345	COG0625	glutathione transferase activity
L2Z04_07350	COG0583	DNA-binding transcription factor activity
L2Z04_07355	COG1960	acyl-CoA dehydrogenase activity
L2Z04_07360	COG1960	acyl-CoA dehydrogenase activity
L2Z04_07370	COG2205	protein histidine kinase activity
L2Z04_07375	COG0745	RESPONSE REGULATOR receiver
L2Z04_07380	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z04_07400	COG2096	Adenosyltransferase
L2Z04_07450	COG0285	dihydrofolate synthase activity
L2Z04_07470	COG0450	alkyl hydroperoxide reductase
L2Z04_07485	COG0477	Major facilitator Superfamily
L2Z04_07490	COG1272	protein, Hemolysin III
L2Z04_07520	COG0183	Belongs to the thiolase family
L2Z04_07525	COG2207	Transcriptional regulator
L2Z04_07545	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z04_07565	COG0183	Belongs to the thiolase family
L2Z04_07580	COG2885	chlorophyll binding
L2Z04_07580	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z04_07590	COG1690	Belongs to the RtcB family
L2Z04_07595	COG0833	amino acid
L2Z04_07605	COG2233	PERMEase
L2Z04_07610	COG1217	gtp-binding protein TYPA
L2Z04_07635	COG2094	Belongs to the DNA glycosylase MPG family
L2Z04_07640	COG4772	TonB-dependent receptor
L2Z04_07645	COG1902	pentaerythritol trinitrate reductase activity
L2Z04_07660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z04_07665	COG0354	folic acid binding
L2Z04_07675	COG3189	MarR family transcriptional regulator
L2Z04_07680	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z04_07685	COG3422	double-strand break repair
L2Z04_07725	COG0840	transmembrane signaling receptor activity
L2Z04_07745	COG5510	response to toxic substance
L2Z04_07755	COG2832	Protein of unknown function (DUF454)
L2Z04_07760	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z04_07800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z04_07810	COG1289	transmembrane transporter activity
L2Z04_07815	COG2814	Major facilitator Superfamily
L2Z04_07835	COG1115	amino acid carrier protein
L2Z04_07840	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z04_07845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z04_07850	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z04_07890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z04_07900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z04_07905	COG1077	Cell shape determining protein MreB Mrl
L2Z04_07910	COG1792	Involved in formation and maintenance of cell shape
L2Z04_07915	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z04_07920	COG0424	maF-like protein
L2Z04_07925	COG1530	ribonuclease E activity
L2Z04_07935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z04_07945	COG0560	Phosphoserine phosphatase
L2Z04_07955	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z04_07980	COG2207	Transcriptional regulator
L2Z04_08000	COG1113	amino acid transport
L2Z04_08005	COG2828	Protein conserved in bacteria
L2Z04_08010	COG0142	geranyltranstransferase activity
L2Z04_08015	COG2315	Protein conserved in bacteria
L2Z04_08030	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z04_08050	COG2194	sulfuric ester hydrolase activity
L2Z04_08055	COG0745	RESPONSE REGULATOR receiver
L2Z04_08060	COG0642	Histidine kinase
L2Z04_08070	COG0004	ammonium transporteR
L2Z04_08075	COG0583	DNA-binding transcription factor activity
L2Z04_08095	COG0525	valine-tRNA ligase activity
L2Z04_08105	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_08115	COG0393	Putative heavy-metal-binding
L2Z04_08120	COG0393	Putative heavy-metal-binding
L2Z04_08125	COG1538	Outer membrane efflux protein
L2Z04_08135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z04_08140	COG0671	phosphoesterase, PA-phosphatase related
L2Z04_08170	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z04_08185	COG1648	precorrin-2 dehydrogenase activity
L2Z04_08185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z04_08190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z04_08195	COG1733	regulation of RNA biosynthetic process
L2Z04_08205	COG0531	amino acid
L2Z04_08220	COG0321	lipoyl(octanoyl) transferase activity
L2Z04_08225	COG2921	Belongs to the UPF0250 family
L2Z04_08265	COG2009	succinate dehydrogenase
L2Z04_08270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z04_08275	COG1053	succinate dehydrogenase
L2Z04_08280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z04_08305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z04_08330	COG4372	Transposase
L2Z04_08340	COG2354	Protein conserved in bacteria
L2Z04_08345	COG2321	neutral zinc metallopeptidase
L2Z04_08365	COG2843	Capsule synthesis protein
L2Z04_08380	COG0589	response to stress
L2Z04_08400	COG0505	Belongs to the CarA family
L2Z04_08425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z04_08430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z04_08480	COG0477	Major facilitator Superfamily
L2Z04_08485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z04_08500	COG1597	lipid kinase activity
L2Z04_08505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z04_08530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z04_08535	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z04_08555	COG0741	lytic transglycosylase activity
L2Z04_08575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z04_08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z04_08620	COG0778	Nitroreductase
L2Z04_08635	COG1929	Belongs to the glycerate kinase type-1 family
L2Z04_08640	COG0243	molybdopterin cofactor binding
L2Z04_08645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z04_08650	COG3339	Conserved Protein
L2Z04_08660	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z04_08675	COG1113	amino acid transport
L2Z04_08685	COG0019	diaminopimelate decarboxylase activity
L2Z04_08695	COG1280	lysine exporter protein (LysE YggA)
L2Z04_08700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z04_08730	COG0463	Glycosyl transferase, family 2
L2Z04_08750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z04_08785	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z04_08790	COG1136	(ABC) transporter
L2Z04_08795	COG2333	competence protein COMEC
L2Z04_08795	COG0658	competence protein
L2Z04_08805	COG0616	signal peptide processing
L2Z04_08805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z04_08810	COG0596	Alpha beta hydrolase
L2Z04_08815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z04_08825	COG0628	permease
L2Z04_08860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z04_08880	COG0823	Involved in the tonB-independent uptake of proteins
L2Z04_08900	COG0824	Thioesterase
L2Z04_08905	COG1473	amidohydrolase
L2Z04_08925	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z04_08925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z04_08930	COG2814	Major facilitator Superfamily
L2Z04_08940	COG1024	Enoyl-CoA hydratase
L2Z04_08945	COG1056	cytidyltransferase-related domain
L2Z04_08945	COG1051	belongs to the nudix hydrolase family
L2Z04_08955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z04_08970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z04_09000	COG0583	DNA-binding transcription factor activity
L2Z04_09005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z04_09010	COG4208	sulfate ABC transporter
L2Z04_09015	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z04_09025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z04_09030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z04_09035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z04_09055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z04_09070	COG0681	Belongs to the peptidase S26 family
L2Z04_09085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z04_09095	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z04_09100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z04_09110	COG4221	oxidoreductase activity
L2Z04_09140	COG0436	Aminotransferase
L2Z04_09160	COG0556	nucleotide-excision repair
L2Z04_09215	COG2070	2-Nitropropane dioxygenase
L2Z04_09245	COG1215	transferase activity, transferring glycosyl groups
L2Z04_09260	COG0415	Belongs to the DNA photolyase family
L2Z04_09270	COG1252	NADH dehydrogenase
L2Z04_09275	COG1686	Belongs to the peptidase S11 family
L2Z04_09290	COG1187	pseudouridine synthase activity
L2Z04_09315	COG0477	Major facilitator Superfamily
L2Z04_09320	COG0583	DNA-binding transcription factor activity
L2Z04_09325	COG1823	symporter activity
L2Z04_09335	COG0612	Peptidase, M16
L2Z04_09360	COG0352	thiamine-phosphate diphosphorylase activity
L2Z04_09400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z04_09415	COG1309	transcriptional regulator
L2Z04_09425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z04_09430	COG0076	glutamate decarboxylase activity
L2Z04_09440	COG1522	sequence-specific DNA binding
L2Z04_09445	COG3961	Belongs to the TPP enzyme family
L2Z04_09450	COG1113	amino acid transport
L2Z04_09455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z04_09460	COG0573	inorganic phosphate transmembrane transporter activity
L2Z04_09470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z04_09475	COG0616	signal peptide processing
L2Z04_09510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z04_09515	COG1686	Belongs to the peptidase S11 family
L2Z04_09540	COG0583	DNA-binding transcription factor activity
L2Z04_09545	COG1067	ATP-dependent peptidase activity
L2Z04_09590	COG1966	Carbon starvation protein
L2Z04_09595	COG2879	small protein
L2Z04_09640	COG4372	Transposase
L2Z04_09645	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z04_09645	COG2508	Transcriptional regulator
L2Z04_09665	COG1113	amino acid transport
L2Z04_09670	COG0583	DNA-binding transcription factor activity
L2Z04_09675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z04_09680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z04_09690	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_09700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z04_09705	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z04_09705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z04_09740	COG2814	Major facilitator Superfamily
L2Z04_09745	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z04_09755	COG1309	transcriptional regulator
L2Z04_09775	COG1741	Belongs to the pirin family
L2Z04_09785	COG2964	Protein conserved in bacteria
L2Z04_09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z04_09805	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z04_09810	COG4605	iron ion homeostasis
L2Z04_09815	COG4604	ABC transporter, ATP-binding protein
L2Z04_09820	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z04_09825	COG4774	siderophore transport
L2Z04_09835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z04_09840	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z04_09845	COG1535	isochorismatase
L2Z04_09845	COG3433	isochorismatase activity
L2Z04_09855	COG1132	(ABC) transporter
L2Z04_09860	COG1132	(ABC) transporter
L2Z04_09865	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z04_09875	COG1169	isochorismate synthase
L2Z04_09890	COG3739	integral membrane protein
L2Z04_09915	COG0302	gtp cyclohydrolase
L2Z04_09925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z04_09955	COG0308	aminopeptidase N
L2Z04_09960	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z04_09975	COG0174	glutamine synthetase
L2Z04_09985	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z04_10020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z04_10025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z04_10030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z04_10060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z04_10065	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z04_10070	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z04_10085	COG1960	acyl-CoA dehydrogenase activity
L2Z04_10090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z04_10095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z04_10105	COG2223	nitrite transmembrane transporter activity
L2Z04_10115	COG0024	Methionine aminopeptidase
L2Z04_10120	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z04_10135	COG2207	Transcriptional regulator
L2Z04_10160	COG2951	lytic endotransglycosylase activity
L2Z04_10165	COG0772	Belongs to the SEDS family
L2Z04_10180	COG0842	Transport permease protein
L2Z04_10185	COG1131	(ABC) transporter
L2Z04_10230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z04_10245	COG4215	(ABC) transporter
L2Z04_10250	COG4160	amino acid transport
L2Z04_10255	COG4598	ABC transporter
L2Z04_10265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z04_10270	COG0826	peptidase U32
L2Z04_10275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z04_10290	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z04_10300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z04_10315	COG0642	Histidine kinase
L2Z04_10325	COG0494	nUDIX hydrolase
L2Z04_10335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z04_10340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z04_10345	COG3139	Protein of unknown function (DUF1315)
L2Z04_10350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z04_10355	COG1301	dicarboxylic acid transport
L2Z04_10360	COG1960	acyl-CoA dehydrogenase activity
L2Z04_10365	COG2819	hydrolase of the alpha beta superfamily
L2Z04_10375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z04_10385	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z04_10390	COG1234	tRNA 3'-trailer cleavage
L2Z04_10420	COG2363	Small membrane protein
L2Z04_10445	COG0513	Belongs to the DEAD box helicase family
L2Z04_10455	COG0778	Nitroreductase
L2Z04_10485	COG1286	toxin biosynthetic process
L2Z04_10510	COG4783	chaperone-mediated protein folding
L2Z04_10515	COG1610	YqeY-like protein
L2Z04_10615	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z04_10680	COG0477	Major facilitator Superfamily
L2Z04_10710	COG2985	domain, Protein
L2Z04_10720	COG2995	paraquat-inducible protein a
L2Z04_10725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z04_10725	COG3008	intermembrane lipid transfer
L2Z04_10735	COG1794	racemase activity, acting on amino acids and derivatives
L2Z04_10765	COG1301	dicarboxylic acid transport
L2Z04_10775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z04_10780	COG2011	ABC-type metal ion transport system permease component
L2Z04_10785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z04_10790	COG1464	Belongs to the NlpA lipoprotein family
L2Z04_10795	COG0151	Belongs to the GarS family
L2Z04_10800	COG0138	bifunctional purine biosynthesis protein purh
L2Z04_10805	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z04_10835	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z04_10845	COG1305	Transglutaminase-like
L2Z04_10855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z04_10860	COG0305	Participates in initiation and elongation during chromosome replication
L2Z04_10885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z04_10895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z04_10900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z04_10925	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z04_10925	COG0726	polysaccharide deacetylase
L2Z04_10930	COG1215	transferase activity, transferring glycosyl groups
L2Z04_10935	COG3658	cytochrome
L2Z04_10945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z04_10960	COG0583	DNA-binding transcription factor activity
L2Z04_10985	COG4372	Transposase
L2Z04_11005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z04_11020	COG1960	acyl-CoA dehydrogenase activity
L2Z04_11025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z04_11030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z04_11055	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z04_11060	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z04_11070	COG2205	protein histidine kinase activity
L2Z04_11075	COG0745	RESPONSE REGULATOR receiver
L2Z04_11080	COG0174	glutamine synthetase
L2Z04_11100	COG0729	surface antigen
L2Z04_11125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z04_11130	COG2814	Major facilitator Superfamily
L2Z04_11145	COG0583	DNA-binding transcription factor activity
L2Z04_11160	COG1187	pseudouridine synthase activity
L2Z04_11180	COG0802	atpase or kinase
L2Z04_11185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z04_11195	COG1923	regulation of RNA biosynthetic process
L2Z04_11200	COG0697	spore germination
L2Z04_11215	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z04_11225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z04_11230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z04_11230	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z04_11235	COG4302	ethanolamine ammonia-lyase activity
L2Z04_11240	COG4303	Ethanolamine ammonia lyase large subunit
L2Z04_11245	COG0531	amino acid
L2Z04_11265	COG1454	alcohol dehydrogenase
L2Z04_11270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z04_11280	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z04_11300	COG0308	aminopeptidase N
L2Z04_11310	COG4221	oxidoreductase activity
L2Z04_11320	COG1605	Chorismate mutase
L2Z04_11350	COG1309	transcriptional regulator
L2Z04_11360	COG0668	transmembrane transport
L2Z04_11390	COG4773	Receptor
L2Z04_11410	COG0488	(ABC) transporter
L2Z04_11415	COG0589	response to stress
L2Z04_11440	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z04_11450	COG3135	benzoate transporter
L2Z04_11455	COG1522	sequence-specific DNA binding
L2Z04_11465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z04_11470	COG0583	DNA-binding transcription factor activity
L2Z04_11480	COG0183	Belongs to the thiolase family
L2Z04_11490	COG2030	dehydratase
L2Z04_11495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z04_11510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z04_11520	COG0824	Thioesterase
L2Z04_11525	COG1454	alcohol dehydrogenase
L2Z04_11535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z04_11555	COG0069	glutamate synthase activity
L2Z04_11575	COG2814	Major facilitator Superfamily
L2Z04_11590	COG0511	ligase activity, forming carbon-carbon bonds
L2Z04_11610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z04_11610	COG1116	anion transmembrane transporter activity
L2Z04_11615	COG0745	RESPONSE REGULATOR receiver
L2Z04_11625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z04_11625	COG2146	nitrite reductase [NAD(P)H] activity
L2Z04_11630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z04_11635	COG0243	molybdopterin cofactor binding
L2Z04_11645	COG0243	molybdopterin cofactor binding
L2Z04_11650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z04_11665	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z04_11665	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z04_11670	COG0303	'Molybdopterin
L2Z04_11680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z04_11685	COG0697	spore germination
L2Z04_11705	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z04_11710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z04_11765	COG2204	response regulator
L2Z04_11770	COG3852	Histidine kinase
L2Z04_11790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z04_11795	COG0575	Belongs to the CDS family
L2Z04_11830	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z04_11845	COG2137	regulation of response to DNA damage stimulus
L2Z04_11855	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z04_11860	COG1011	Hydrolase
L2Z04_11895	COG1113	amino acid transport
L2Z04_11915	COG0659	secondary active sulfate transmembrane transporter activity
L2Z04_11920	COG2135	peptidase activity
L2Z04_11935	COG5001	Diguanylate cyclase
L2Z04_11935	COG3300	MHYT domain
L2Z04_11955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z04_11955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z04_11955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z04_11960	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z04_11965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z04_11965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z04_11995	COG0024	Methionine aminopeptidase
L2Z04_12000	COG0583	DNA-binding transcription factor activity
L2Z04_12010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z04_12015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z04_12020	COG0517	IMP dehydrogenase activity
L2Z04_12020	COG0516	GMP reductase activity
L2Z04_12045	COG0552	protein localization to endoplasmic reticulum
L2Z04_12055	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z04_12070	COG4890	Cyd operon protein YbgT
L2Z04_12075	COG1294	oxidase, subunit
L2Z04_12095	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z04_12105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z04_12110	COG4774	siderophore transport
L2Z04_12125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z04_12130	COG0569	domain protein
L2Z04_12135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z04_12165	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z04_12170	COG0542	response to heat
L2Z04_12195	COG1902	pentaerythritol trinitrate reductase activity
L2Z04_12195	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z04_12240	COG2323	membrane
L2Z04_12245	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z04_12255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z04_12260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z04_12265	COG0183	Belongs to the thiolase family
L2Z04_12270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z04_12275	COG0596	Alpha beta hydrolase
L2Z04_12280	COG2271	Major facilitator Superfamily
L2Z04_12285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z04_12290	COG3485	protocatechuate 3,4-dioxygenase
L2Z04_12295	COG3485	protocatechuate 3,4-dioxygenase
L2Z04_12300	COG0710	3-dehydroquinate dehydratase activity
L2Z04_12305	COG3420	alginic acid biosynthetic process
L2Z04_12310	COG3659	wide pore channel activity
L2Z04_12315	COG4993	Dehydrogenase
L2Z04_12325	COG2391	methyltransferase activity
L2Z04_12340	COG1414	Transcriptional regulator
L2Z04_12345	COG0583	DNA-binding transcription factor activity
L2Z04_12350	COG1960	acyl-CoA dehydrogenase activity
L2Z04_12375	COG2814	Major facilitator Superfamily
L2Z04_12385	COG0154	amidase activity
L2Z04_12405	COG4638	Rieske (2fe-2S)
L2Z04_12415	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_12425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z04_12435	COG3733	amine oxidase
L2Z04_12445	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_12455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z04_12460	COG0183	Belongs to the thiolase family
L2Z04_12465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z04_12470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z04_12480	COG4829	muconolactone delta-isomerase
L2Z04_12485	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z04_12490	COG0583	DNA-binding transcription factor activity
L2Z04_12500	COG2186	Transcriptional regulator
L2Z04_12535	COG2188	Transcriptional regulator
L2Z04_12550	COG0583	DNA-binding transcription factor activity
L2Z04_12580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z04_12610	COG1566	PFAM secretion protein HlyD family protein
L2Z04_12625	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_12630	COG0129	dihydroxy-acid dehydratase activity
L2Z04_12640	COG0583	DNA-binding transcription factor activity
L2Z04_12645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z04_12655	COG2084	Dehydrogenase
L2Z04_12660	COG2207	Transcriptional regulator
L2Z04_12675	COG1064	alcohol dehydrogenase
L2Z04_12685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z04_12690	COG1120	ATPase activity
L2Z04_12710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z04_12955	COG5410	chromosome segregation
L2Z04_13060	COG1598	PFAM Uncharacterised protein family UPF0150
L2Z04_13065	COG4372	Transposase
L2Z04_13090	COG1196	nuclear chromosome segregation
L2Z04_13090	COG0741	lytic transglycosylase activity
L2Z04_13090	COG0739	heme binding
L2Z04_13220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z04_13270	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_13285	COG2207	Transcriptional regulator
L2Z04_13295	COG2205	protein histidine kinase activity
L2Z04_13300	COG0745	RESPONSE REGULATOR receiver
L2Z04_13305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z04_13310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z04_13315	COG1538	Outer membrane efflux protein
L2Z04_13325	COG2072	flavoprotein involved in K transport
L2Z04_13345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z04_13365	COG3539	Fimbrial protein
L2Z04_13395	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z04_13405	COG0753	catalase activity
L2Z04_13420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z04_13480	COG1535	isochorismatase
L2Z04_13480	COG3433	isochorismatase activity
L2Z04_13485	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_13490	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z04_13495	COG4149	molybdate abc transporter
L2Z04_13500	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z04_13510	COG4638	Rieske (2fe-2S)
L2Z04_13515	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z04_13520	COG0543	2 iron, 2 sulfur cluster binding
L2Z04_13520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z04_13545	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_13560	COG2207	Transcriptional regulator
L2Z04_13570	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_13575	COG2610	gluconate transmembrane transporter activity
L2Z04_13585	COG0583	DNA-binding transcription factor activity
L2Z04_13595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z04_13600	COG2031	fatty acid transporter
L2Z04_13605	COG0183	Belongs to the thiolase family
L2Z04_13610	COG0583	DNA-binding transcription factor activity
L2Z04_13615	COG0583	DNA-binding transcription factor activity
L2Z04_13630	COG1027	Aspartate ammonia-lyase
L2Z04_13640	COG0477	Major facilitator Superfamily
L2Z04_13660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z04_13665	COG4521	taurine ABC transporter
L2Z04_13680	COG2188	Transcriptional regulator
L2Z04_13690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z04_13695	COG1733	regulation of RNA biosynthetic process
L2Z04_13700	COG2207	Transcriptional regulator
L2Z04_13700	COG3708	Transcriptional regulator
L2Z04_13715	COG0730	response to heat
L2Z04_13730	COG3453	Protein conserved in bacteria
L2Z04_13730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z04_13740	COG3781	membrane
L2Z04_13745	COG1063	alcohol dehydrogenase
L2Z04_13755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z04_13760	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z04_13765	COG0022	dehydrogenase e1 component
L2Z04_13770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z04_13775	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z04_13790	COG3706	GGDEF domain
L2Z04_13805	COG0133	tryptophan synthase activity
L2Z04_13815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z04_13850	COG2826	transposase and inactivated derivatives, IS30 family
L2Z04_13855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z04_13880	COG2226	methyltransferase
L2Z04_13935	COG0842	Transport permease protein
L2Z04_13940	COG0842	Transport permease protein
L2Z04_13945	COG1131	(ABC) transporter
L2Z04_13960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z04_13970	COG4773	Receptor
L2Z04_13990	COG0730	response to heat
L2Z04_13995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z04_14015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z04_14030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z04_14070	COG4264	IucA IucC family
L2Z04_14075	COG4264	IucA IucC family
L2Z04_14095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z04_14110	COG1960	acyl-CoA dehydrogenase activity
L2Z04_14115	COG1960	acyl-CoA dehydrogenase activity
L2Z04_14120	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z04_14125	COG2207	Transcriptional regulator
L2Z04_14130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z04_14135	COG0776	regulation of translation
L2Z04_14160	COG0822	iron-sulfur transferase activity
L2Z04_14165	COG0316	Belongs to the HesB IscA family
L2Z04_14195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z04_14215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z04_14220	COG0702	epimerase
L2Z04_14255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z04_14265	COG0339	signal peptide processing
L2Z04_14315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z04_14320	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z04_14360	COG0776	regulation of translation
L2Z04_14425	COG0084	hydrolase, TatD family'
L2Z04_14445	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z04_14450	COG1132	(ABC) transporter
L2Z04_14460	COG0811	peptide transport
L2Z04_14465	COG1475	DNA binding
L2Z04_14470	COG1192	Involved in chromosome partitioning
L2Z04_14480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z04_14495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z04_14500	COG0191	fructose-bisphosphate aldolase activity
L2Z04_14520	COG0424	maF-like protein
L2Z04_14525	COG2850	peptidyl-arginine hydroxylation
L2Z04_14535	COG0640	Transcriptional regulator
L2Z04_14545	COG3619	membrane
L2Z04_14550	COG3122	Protein conserved in bacteria
L2Z04_14555	COG1132	(ABC) transporter
L2Z04_14575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z04_14580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z04_14590	COG0506	proline dehydrogenase activity
L2Z04_14590	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z04_14590	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z04_14595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z04_14610	COG3698	Phosphodiester glycosidase
L2Z04_14620	COG2353	YceI-like domain
L2Z04_14630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z04_14675	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z04_14675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z04_14700	COG3539	Fimbrial protein
L2Z04_14705	COG3121	Chaperone
L2Z04_14730	COG0697	spore germination
L2Z04_14740	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z04_14750	COG0583	DNA-binding transcription factor activity
L2Z04_14770	COG1309	transcriptional regulator
L2Z04_14785	COG1522	sequence-specific DNA binding
L2Z04_14795	COG1126	abc transporter atp-binding protein
L2Z04_14800	COG0765	amino acid transport
L2Z04_14805	COG0765	amino acid transport
L2Z04_14835	COG1464	Belongs to the NlpA lipoprotein family
L2Z04_14845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z04_14850	COG2011	ABC-type metal ion transport system permease component
L2Z04_14855	COG0012	GTP binding
L2Z04_14880	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z04_14920	COG0386	Belongs to the glutathione peroxidase family
L2Z04_14930	COG0436	Aminotransferase
L2Z04_14970	COG3634	alkyl hydroperoxide reductase activity
L2Z04_14985	COG0583	DNA-binding transcription factor activity
L2Z04_14990	COG0798	PFAM Bile acid sodium symporter
L2Z04_14995	COG0640	Transcriptional regulator
L2Z04_15010	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z04_15020	COG0583	DNA-binding transcription factor activity
L2Z04_15030	COG1953	Uracil, thiamine, allantoin
L2Z04_15040	COG2175	clavaminate synthase activity
L2Z04_15045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z04_15050	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z04_15055	COG4521	taurine ABC transporter
L2Z04_15065	COG0477	Major facilitator Superfamily
L2Z04_15085	COG1271	oxidase subunit
L2Z04_15090	COG1294	oxidase, subunit
L2Z04_15100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z04_15120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z04_15140	COG3052	prosthetic group binding
L2Z04_15145	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z04_15155	COG2814	Major facilitator Superfamily
L2Z04_15175	COG1346	cytolysis
L2Z04_15185	COG0583	DNA-binding transcription factor activity
L2Z04_15190	COG0625	glutathione transferase activity
L2Z04_15195	COG0625	glutathione transferase activity
L2Z04_15200	COG0583	DNA-binding transcription factor activity
L2Z04_15215	COG1045	serine acetyltransferase
L2Z04_15220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z04_15225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z04_15235	COG1280	lysine exporter protein (LysE YggA)
L2Z04_15250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z04_15255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z04_15260	COG1126	abc transporter atp-binding protein
L2Z04_15265	COG0765	amino acid transport
L2Z04_15270	COG0765	amino acid transport
L2Z04_15290	COG0784	Response regulator, receiver
L2Z04_15290	COG2205	protein histidine kinase activity
L2Z04_15330	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_15380	COG0583	DNA-binding transcription factor activity
L2Z04_15400	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z04_15405	COG1309	transcriptional regulator
L2Z04_15410	COG1960	acyl-CoA dehydrogenase activity
L2Z04_15415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z04_15420	COG1024	Enoyl-CoA hydratase
L2Z04_15425	COG4770	biotin carboxylase activity
L2Z04_15435	COG0583	DNA-binding transcription factor activity
L2Z04_15450	COG1960	acyl-CoA dehydrogenase activity
L2Z04_15460	COG2814	Major facilitator Superfamily
L2Z04_15470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z04_15475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z04_15480	COG2814	Major facilitator Superfamily
L2Z04_15485	COG1960	acyl-CoA dehydrogenase activity
L2Z04_15490	COG1024	Enoyl-CoA hydratase
L2Z04_15495	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_15500	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z04_15505	COG0183	Belongs to the thiolase family
L2Z04_15515	COG2814	Major facilitator Superfamily
L2Z04_15525	COG1024	Enoyl-CoA hydratase
L2Z04_15540	COG1960	acyl-CoA dehydrogenase activity
L2Z04_15545	COG2814	Major facilitator Superfamily
L2Z04_15550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z04_15555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z04_15570	COG3842	ATPase activity
L2Z04_15575	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z04_15585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z04_15590	COG1414	Transcriptional regulator
L2Z04_15600	COG0583	DNA-binding transcription factor activity
L2Z04_15605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z04_15610	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_15630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z04_15640	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_15645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z04_15650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z04_15655	COG2267	carboxylic ester hydrolase activity
L2Z04_15675	COG3038	cytochrome b561
L2Z04_15680	COG0753	catalase activity
L2Z04_15710	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z04_15720	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z04_15725	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z04_15730	COG0183	Belongs to the thiolase family
L2Z04_15735	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z04_15740	COG1024	Enoyl-CoA hydratase
L2Z04_15745	COG1024	Enoyl-CoA hydratase
L2Z04_15750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z04_15755	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z04_15760	COG3396	Phenylacetate-CoA oxygenase
L2Z04_15765	COG3460	Phenylacetate-CoA oxygenase
L2Z04_15770	COG3396	Phenylacetate-CoA oxygenase
L2Z04_15775	COG2030	dehydratase
L2Z04_15775	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_15780	COG1760	l-serine dehydratase
L2Z04_15785	COG0531	amino acid
L2Z04_15790	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_15805	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z04_15815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z04_15835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z04_15845	COG0789	Transcriptional regulator
L2Z04_15860	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z04_15875	COG2807	transmembrane transport
L2Z04_15880	COG0590	tRNA wobble adenosine to inosine editing
L2Z04_15990	COG2826	transposase and inactivated derivatives, IS30 family
L2Z04_16005	COG1116	anion transmembrane transporter activity
L2Z04_16010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z04_16020	COG0864	Transcriptional regulator
L2Z04_16040	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z04_16045	COG0439	Biotin carboxylase
L2Z04_16070	COG1309	transcriptional regulator
L2Z04_16090	COG0038	chloride channel
L2Z04_16095	COG4770	biotin carboxylase activity
L2Z04_16115	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z04_16120	COG0583	DNA-binding transcription factor activity
L2Z04_16170	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z04_16190	COG2814	Major facilitator Superfamily
L2Z04_16205	COG1560	Kdo2-lipid A biosynthetic process
L2Z04_16215	COG5006	permease, DMT superfamily
L2Z04_16220	COG1522	sequence-specific DNA binding
L2Z04_16235	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z04_16245	COG4122	O-methyltransferase activity
L2Z04_16275	COG1538	Outer membrane efflux protein
L2Z04_16280	COG1137	ATPase activity
L2Z04_16285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z04_16295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z04_16300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z04_16300	COG0517	IMP dehydrogenase activity
L2Z04_16335	COG2814	Major facilitator Superfamily
L2Z04_16370	COG1278	Cold shock
L2Z04_16375	COG1280	lysine exporter protein (LysE YggA)
L2Z04_16405	COG1570	exodeoxyribonuclease VII activity
L2Z04_16455	COG0583	DNA-binding transcription factor activity
L2Z04_16465	COG4638	Rieske (2fe-2S)
L2Z04_16470	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z04_16475	COG0633	Ferredoxin
L2Z04_16475	COG0543	2 iron, 2 sulfur cluster binding
L2Z04_16480	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_16485	COG3135	benzoate transporter
L2Z04_16490	COG2814	Major facilitator Superfamily
L2Z04_16505	COG1643	Atp-dependent helicase
L2Z04_16510	COG0450	alkyl hydroperoxide reductase
L2Z04_16520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z04_16530	COG3634	alkyl hydroperoxide reductase activity
L2Z04_16550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z04_16555	COG0625	glutathione transferase activity
L2Z04_16565	COG2885	chlorophyll binding
L2Z04_16600	COG0542	response to heat
L2Z04_16615	COG1765	OsmC-like protein
L2Z04_16635	COG0667	Aldo Keto reductase
L2Z04_16650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z04_16660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z04_16670	COG0527	aspartate kinase activity
L2Z04_16680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z04_16690	COG3038	cytochrome b561
L2Z04_16695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z04_16700	COG2252	PERMEase
L2Z04_16710	COG2072	flavoprotein involved in K transport
L2Z04_16725	COG1741	Belongs to the pirin family
L2Z04_16730	COG1309	transcriptional regulator
L2Z04_16740	COG0300	oxidoreductase activity
L2Z04_16760	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z04_16780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z04_16810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z04_16820	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z04_16820	COG0352	thiamine-phosphate diphosphorylase activity
L2Z04_16820	COG0351	phosphomethylpyrimidine kinase
L2Z04_16825	COG1652	LysM domain
L2Z04_16855	COG2826	transposase and inactivated derivatives, IS30 family
L2Z04_16865	COG3101	peptidyl-lysine hydroxylation
L2Z04_16870	COG0009	L-threonylcarbamoyladenylate synthase
L2Z04_16875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z04_16880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z04_16895	COG4106	trans-aconitate 2-methyltransferase activity
L2Z04_16910	COG0596	Alpha beta hydrolase
L2Z04_16910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z04_16910	COG2226	methyltransferase
L2Z04_16915	COG1877	trehalose-phosphatase activity
L2Z04_16920	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z04_16925	COG2223	nitrite transmembrane transporter activity
L2Z04_16945	COG1196	nuclear chromosome segregation
L2Z04_16955	COG0730	response to heat
L2Z04_16970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z04_16980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z04_17035	COG0489	protein tyrosine kinase activity
L2Z04_17045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z04_17045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z04_17075	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z04_17080	COG2081	HI0933 family
L2Z04_17090	COG0668	transmembrane transport
L2Z04_17110	COG0583	DNA-binding transcription factor activity
L2Z04_17130	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z04_17135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z04_17165	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z04_17205	COG0745	RESPONSE REGULATOR receiver
L2Z04_17225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z04_17235	COG2205	protein histidine kinase activity
L2Z04_17295	COG4372	Transposase
L2Z04_17325	COG4993	Dehydrogenase
L2Z04_17350	COG0384	phenazine biosynthesis protein PhzF
L2Z04_17375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z04_17390	COG0583	DNA-binding transcription factor activity
L2Z04_17420	COG0583	DNA-binding transcription factor activity
L2Z04_17435	COG0583	DNA-binding transcription factor activity
L2Z04_17440	COG1053	succinate dehydrogenase
L2Z04_17450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z04_17455	COG2814	Major facilitator Superfamily
L2Z04_17460	COG1960	acyl-CoA dehydrogenase activity
L2Z04_17465	COG0583	DNA-binding transcription factor activity
L2Z04_17470	COG1063	alcohol dehydrogenase
L2Z04_17500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z04_17505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z04_17510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z04_17525	COG3667	copper resistance
L2Z04_17530	COG2132	Multicopper oxidase
L2Z04_17540	COG0561	phosphatase activity
L2Z04_17545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z04_17570	COG1214	PFAM Peptidase M22, glycoprotease
L2Z04_17620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z04_17630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z04_17635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z04_17640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z04_17705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z04_17715	COG1846	Transcriptional regulator
L2Z04_17720	COG1764	response to oxidative stress
L2Z04_17760	COG0037	tRNA processing
L2Z04_17770	COG0248	Ppx GppA phosphatase
L2Z04_17800	COG0072	phenylalanine-tRNA ligase activity
L2Z04_17845	COG1238	metal cluster binding
L2Z04_17850	COG0625	glutathione transferase activity
L2Z04_17865	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z04_17870	COG3028	Belongs to the UPF0307 family
L2Z04_17875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z04_17895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z04_17900	COG0617	tRNA 3'-terminal CCA addition
L2Z04_17905	COG1555	photosystem II stabilization
L2Z04_17910	COG3956	TIGRFAM MazG family protein
L2Z04_17920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z04_17940	COG0784	Response regulator, receiver
L2Z04_17940	COG5002	protein histidine kinase activity
L2Z04_17940	COG2205	protein histidine kinase activity
L2Z04_17945	COG1024	Enoyl-CoA hydratase
L2Z04_17950	COG2084	Dehydrogenase
L2Z04_17955	COG3622	Belongs to the hyi family
L2Z04_17985	COG0697	spore germination
L2Z04_17995	COG2814	Major facilitator Superfamily
L2Z04_18000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z04_18010	COG0583	DNA-binding transcription factor activity
L2Z04_18020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z04_18035	COG0084	hydrolase, TatD family'
L2Z04_18050	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z04_18080	COG0440	acetolactate synthase activity
L2Z04_18085	COG0028	Belongs to the TPP enzyme family
L2Z04_18110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z04_18115	COG1136	(ABC) transporter
L2Z04_18115	COG0577	efflux transmembrane transporter activity
L2Z04_18120	COG1538	Outer membrane efflux protein
L2Z04_18135	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z04_18140	COG1162	GTPase activity
L2Z04_18150	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z04_18170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z04_18175	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z04_18215	COG2986	histidine ammonia-lyase
L2Z04_18230	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z04_18245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z04_18290	COG1426	Protein conserved in bacteria
L2Z04_18325	COG0793	Belongs to the peptidase S41A family
L2Z04_18340	COG2267	carboxylic ester hydrolase activity
L2Z04_18350	COG1012	belongs to the aldehyde dehydrogenase family
L2Z04_18355	COG3265	gluconokinase activity
L2Z04_18365	COG0800	Aldolase
L2Z04_18375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z04_18380	COG0280	phosphate acetyltransferase
L2Z04_18380	COG0857	belongs to the CobB CobQ family
L2Z04_18385	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z04_18385	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z04_18405	COG0740	serine-type endopeptidase activity