locus-tag	class	description
L2Z48_00020	COG0589	response to stress
L2Z48_00025	COG0659	secondary active sulfate transmembrane transporter activity
L2Z48_00085	COG0347	Belongs to the P(II) protein family
L2Z48_00090	COG0004	ammonium transporteR
L2Z48_00100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z48_00100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z48_00140	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z48_00145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z48_00150	COG0793	Belongs to the peptidase S41A family
L2Z48_00165	COG2197	response regulator
L2Z48_00175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z48_00185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z48_00190	COG4974	Belongs to the 'phage' integrase family
L2Z48_00215	COG0772	Belongs to the SEDS family
L2Z48_00220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z48_00225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z48_00230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z48_00255	COG0697	spore germination
L2Z48_00260	COG1538	Outer membrane efflux protein
L2Z48_00280	COG3275	phosphorelay sensor kinase activity
L2Z48_00290	COG0181	hydroxymethylbilane synthase activity
L2Z48_00335	COG1716	ATPase activity
L2Z48_00340	COG0546	phosphoglycolate phosphatase activity
L2Z48_00445	COG0596	Alpha beta hydrolase
L2Z48_00450	COG2056	Na+-H+ antiporter family
L2Z48_00465	COG0326	Molecular chaperone. Has ATPase activity
L2Z48_00480	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z48_00545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z48_00550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z48_00550	COG2169	Transcriptional regulator
L2Z48_00580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z48_00590	COG0497	DNA recombination
L2Z48_00605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z48_00615	COG0237	dephospho-CoA kinase activity
L2Z48_00620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z48_00670	COG0195	Participates in both transcription termination and antitermination
L2Z48_00685	COG1320	monovalent cation:proton antiporter activity
L2Z48_00690	COG2212	antiporter activity
L2Z48_00695	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z48_00700	COG0651	ATP synthesis coupled electron transport
L2Z48_00705	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z48_00710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z48_00710	COG2111	Na H antiporter
L2Z48_00725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z48_00730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z48_00745	COG2226	methyltransferase
L2Z48_00765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z48_00770	COG1074	ATP-dependent DNA helicase activity
L2Z48_00775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z48_00780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z48_00795	COG0598	Magnesium transport protein CorA
L2Z48_00800	COG0789	Transcriptional regulator
L2Z48_00805	COG0484	heat shock protein binding
L2Z48_00815	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z48_00820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z48_00820	COG0475	glutathione-regulated potassium exporter activity
L2Z48_00825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z48_00845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z48_00855	COG4535	Mg2 and Co2 transporter CorC
L2Z48_00860	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z48_00865	COG0644	oxidoreductase
L2Z48_00865	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z48_00875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z48_00890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z48_00895	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z48_00935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z48_00950	COG0534	Mate efflux family protein
L2Z48_00960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z48_00965	COG4221	oxidoreductase activity
L2Z48_00970	COG0583	DNA-binding transcription factor activity
L2Z48_00985	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z48_00990	COG1530	ribonuclease E activity
L2Z48_01000	COG0546	phosphoglycolate phosphatase activity
L2Z48_01005	COG2378	regulation of single-species biofilm formation
L2Z48_01010	COG0625	glutathione transferase activity
L2Z48_01020	COG0583	DNA-binding transcription factor activity
L2Z48_01085	COG0473	3-isopropylmalate dehydrogenase activity
L2Z48_01140	COG1301	dicarboxylic acid transport
L2Z48_01150	COG1560	Kdo2-lipid A biosynthetic process
L2Z48_01155	COG1280	lysine exporter protein (LysE YggA)
L2Z48_01160	COG0488	(ABC) transporter
L2Z48_01165	COG2900	Belongs to the SlyX family
L2Z48_01175	COG1733	regulation of RNA biosynthetic process
L2Z48_01200	COG0210	DNA helicase
L2Z48_01205	COG0724	RNA recognition motif
L2Z48_01225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z48_01225	COG4651	solute:proton antiporter activity
L2Z48_01250	COG0788	formyltetrahydrofolate deformylase activity
L2Z48_01350	COG2813	Specifically methylates the guanine in position
L2Z48_01350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z48_01360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z48_01370	COG4774	siderophore transport
L2Z48_01380	COG0740	serine-type endopeptidase activity
L2Z48_01400	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z48_01400	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z48_01405	COG0280	phosphate acetyltransferase
L2Z48_01405	COG0857	belongs to the CobB CobQ family
L2Z48_01410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z48_01420	COG0800	Aldolase
L2Z48_01430	COG3265	gluconokinase activity
L2Z48_01435	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_01445	COG2267	carboxylic ester hydrolase activity
L2Z48_01460	COG0793	Belongs to the peptidase S41A family
L2Z48_01495	COG1426	Protein conserved in bacteria
L2Z48_01540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z48_01550	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z48_01565	COG2986	histidine ammonia-lyase
L2Z48_01605	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_01610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z48_01630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z48_01640	COG1162	GTPase activity
L2Z48_01645	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z48_01660	COG1538	Outer membrane efflux protein
L2Z48_01665	COG0577	efflux transmembrane transporter activity
L2Z48_01665	COG1136	(ABC) transporter
L2Z48_01670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z48_01695	COG0028	Belongs to the TPP enzyme family
L2Z48_01700	COG0440	acetolactate synthase activity
L2Z48_01730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z48_01745	COG0084	hydrolase, TatD family'
L2Z48_01760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z48_01770	COG0583	DNA-binding transcription factor activity
L2Z48_01780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z48_01785	COG2814	Major facilitator Superfamily
L2Z48_01795	COG0697	spore germination
L2Z48_01825	COG3622	Belongs to the hyi family
L2Z48_01830	COG2084	Dehydrogenase
L2Z48_01835	COG1024	Enoyl-CoA hydratase
L2Z48_01840	COG2205	protein histidine kinase activity
L2Z48_01840	COG0784	Response regulator, receiver
L2Z48_01840	COG5002	protein histidine kinase activity
L2Z48_01860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z48_01870	COG3956	TIGRFAM MazG family protein
L2Z48_01875	COG1555	photosystem II stabilization
L2Z48_01880	COG0617	tRNA 3'-terminal CCA addition
L2Z48_01885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z48_01905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z48_01910	COG3028	Belongs to the UPF0307 family
L2Z48_01915	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z48_01930	COG0625	glutathione transferase activity
L2Z48_01935	COG1238	metal cluster binding
L2Z48_01980	COG0072	phenylalanine-tRNA ligase activity
L2Z48_02010	COG0248	Ppx GppA phosphatase
L2Z48_02020	COG0037	tRNA processing
L2Z48_02060	COG1764	response to oxidative stress
L2Z48_02065	COG1846	Transcriptional regulator
L2Z48_02075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z48_02135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z48_02140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z48_02145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z48_02155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2Z48_02205	COG1214	PFAM Peptidase M22, glycoprotease
L2Z48_02230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z48_02235	COG0561	phosphatase activity
L2Z48_02245	COG2132	Multicopper oxidase
L2Z48_02250	COG3667	copper resistance
L2Z48_02265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z48_02270	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z48_02275	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z48_02305	COG1063	alcohol dehydrogenase
L2Z48_02310	COG0583	DNA-binding transcription factor activity
L2Z48_02315	COG1960	acyl-CoA dehydrogenase activity
L2Z48_02320	COG2814	Major facilitator Superfamily
L2Z48_02325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z48_02335	COG1053	succinate dehydrogenase
L2Z48_02340	COG0583	DNA-binding transcription factor activity
L2Z48_02355	COG0583	DNA-binding transcription factor activity
L2Z48_02385	COG0583	DNA-binding transcription factor activity
L2Z48_02400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z48_02425	COG0384	phenazine biosynthesis protein PhzF
L2Z48_02445	COG4993	Dehydrogenase
L2Z48_02515	COG2205	protein histidine kinase activity
L2Z48_02530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z48_02550	COG0745	RESPONSE REGULATOR receiver
L2Z48_02590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z48_02620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z48_02625	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z48_02645	COG0583	DNA-binding transcription factor activity
L2Z48_02665	COG0668	transmembrane transport
L2Z48_02675	COG2081	HI0933 family
L2Z48_02680	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z48_02710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z48_02710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z48_02720	COG0489	protein tyrosine kinase activity
L2Z48_02770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z48_02780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z48_02795	COG0730	response to heat
L2Z48_02805	COG1196	nuclear chromosome segregation
L2Z48_02825	COG2223	nitrite transmembrane transporter activity
L2Z48_02830	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z48_02835	COG1877	trehalose-phosphatase activity
L2Z48_02840	COG2226	methyltransferase
L2Z48_02840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z48_02840	COG0596	Alpha beta hydrolase
L2Z48_02855	COG4106	trans-aconitate 2-methyltransferase activity
L2Z48_02870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z48_02875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z48_02880	COG0009	L-threonylcarbamoyladenylate synthase
L2Z48_02885	COG3101	peptidyl-lysine hydroxylation
L2Z48_02890	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z48_02915	COG1652	LysM domain
L2Z48_02920	COG0351	phosphomethylpyrimidine kinase
L2Z48_02920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z48_02920	COG0352	thiamine-phosphate diphosphorylase activity
L2Z48_02930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z48_02960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z48_02990	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z48_03005	COG0358	DNA primase activity
L2Z48_03015	COG0564	pseudouridine synthase activity
L2Z48_03040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z48_03060	COG0583	DNA-binding transcription factor activity
L2Z48_03065	COG0473	3-isopropylmalate dehydrogenase activity
L2Z48_03075	COG0657	acetylesterase activity
L2Z48_03085	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_03105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z48_03105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z48_03120	COG1981	membrane
L2Z48_03165	COG0456	acetyltransferase
L2Z48_03175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z48_03180	COG0492	ferredoxin-NADP+ reductase activity
L2Z48_03185	COG1674	ftsk spoiiie
L2Z48_03185	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z48_03190	COG1280	lysine exporter protein (LysE YggA)
L2Z48_03210	COG2894	cell division
L2Z48_03225	COG0204	Acyl-transferase
L2Z48_03230	COG2885	chlorophyll binding
L2Z48_03235	COG0210	DNA helicase
L2Z48_03245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z48_03260	COG0121	glutamine amidotransferase
L2Z48_03280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z48_03285	COG0735	belongs to the Fur family
L2Z48_03310	COG0420	3'-5' exonuclease activity
L2Z48_03330	COG1090	epimerase
L2Z48_03345	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z48_03355	COG2814	Major facilitator Superfamily
L2Z48_03360	COG0405	Gamma-glutamyltransferase
L2Z48_03370	COG0582	viral genome integration into host DNA
L2Z48_03430	COG0629	single-stranded DNA binding
L2Z48_03465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
L2Z48_03495	COG0477	Major facilitator Superfamily
L2Z48_03500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z48_03510	COG1595	DNA-templated transcription, initiation
L2Z48_03565	COG0531	amino acid
L2Z48_03570	COG2040	homocysteine
L2Z48_03595	COG1309	transcriptional regulator
L2Z48_03600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z48_03605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z48_03615	COG1607	acyl-coa hydrolase
L2Z48_03625	COG0523	cobalamin synthesis protein
L2Z48_03635	COG4681	YaeQ
L2Z48_03645	COG0726	polysaccharide deacetylase
L2Z48_03645	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z48_03650	COG1215	transferase activity, transferring glycosyl groups
L2Z48_03680	COG1414	Transcriptional regulator
L2Z48_03710	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z48_03715	COG2271	Major facilitator Superfamily
L2Z48_03725	COG2267	carboxylic ester hydrolase activity
L2Z48_03730	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_03745	COG0028	Belongs to the TPP enzyme family
L2Z48_03755	COG0477	Major facilitator Superfamily
L2Z48_03760	COG0242	peptide deformylase activity
L2Z48_03770	COG2207	Transcriptional regulator
L2Z48_03775	COG2223	nitrite transmembrane transporter activity
L2Z48_03790	COG0583	DNA-binding transcription factor activity
L2Z48_03795	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_03800	COG2271	Major facilitator Superfamily
L2Z48_03805	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z48_03810	COG3958	Transketolase
L2Z48_03820	COG0306	phosphate transporter
L2Z48_03840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z48_03885	COG4181	ATPase activity
L2Z48_03890	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z48_03915	COG0583	DNA-binding transcription factor activity
L2Z48_03925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z48_03930	COG1773	rubredoxin
L2Z48_03980	COG2851	Citrate transporter
L2Z48_03985	COG1253	flavin adenine dinucleotide binding
L2Z48_04025	COG0804	urea catabolic process
L2Z48_04035	COG0830	nickel cation binding
L2Z48_04050	COG0742	ribosomal rna small subunit methyltransferase
L2Z48_04055	COG0768	penicillin binding
L2Z48_04080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z48_04085	COG2878	Part of a membrane complex involved in electron transport
L2Z48_04090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z48_04100	COG3384	dioxygenase
L2Z48_04130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z48_04455	COG0739	heme binding
L2Z48_04485	COG3328	transposase activity
L2Z48_04550	COG0006	proline dipeptidase activity
L2Z48_04555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z48_04560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z48_04580	COG1279	arginine transmembrane transporter activity
L2Z48_04585	COG0583	DNA-binding transcription factor activity
L2Z48_04625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z48_04630	COG0741	lytic transglycosylase activity
L2Z48_04630	COG1388	LysM domain
L2Z48_04630	COG0741	lytic transglycosylase activity
L2Z48_04630	COG1388	LysM domain
L2Z48_04640	COG4174	ABC transporter (Permease)
L2Z48_04645	COG4239	(ABC) transporter, permease
L2Z48_04650	COG4172	Belongs to the ABC transporter superfamily
L2Z48_04670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z48_04680	COG2203	Gaf domain
L2Z48_04680	COG3706	GGDEF domain
L2Z48_04680	COG4251	negative regulation of phosphorylation
L2Z48_04680	COG5001	Diguanylate cyclase
L2Z48_04690	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z48_04690	COG1902	pentaerythritol trinitrate reductase activity
L2Z48_04705	COG4269	membrane
L2Z48_04740	COG3209	COG3209 Rhs family protein
L2Z48_04780	COG1113	amino acid transport
L2Z48_04790	COG0531	amino acid
L2Z48_04810	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_04860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2Z48_04965	COG0300	oxidoreductase activity
L2Z48_04975	COG1309	transcriptional regulator
L2Z48_04980	COG1741	Belongs to the pirin family
L2Z48_04995	COG2072	flavoprotein involved in K transport
L2Z48_05005	COG2252	PERMEase
L2Z48_05010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z48_05015	COG3038	cytochrome b561
L2Z48_05025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z48_05035	COG0527	aspartate kinase activity
L2Z48_05045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z48_05055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z48_05070	COG0667	Aldo Keto reductase
L2Z48_05090	COG1765	OsmC-like protein
L2Z48_05105	COG0542	response to heat
L2Z48_05140	COG2885	chlorophyll binding
L2Z48_05150	COG0625	glutathione transferase activity
L2Z48_05155	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z48_05175	COG3634	alkyl hydroperoxide reductase activity
L2Z48_05185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z48_05195	COG0450	alkyl hydroperoxide reductase
L2Z48_05200	COG1643	Atp-dependent helicase
L2Z48_05215	COG2814	Major facilitator Superfamily
L2Z48_05220	COG3135	benzoate transporter
L2Z48_05225	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_05230	COG0543	2 iron, 2 sulfur cluster binding
L2Z48_05230	COG0633	Ferredoxin
L2Z48_05235	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z48_05240	COG4638	Rieske (2fe-2S)
L2Z48_05250	COG0583	DNA-binding transcription factor activity
L2Z48_05300	COG1570	exodeoxyribonuclease VII activity
L2Z48_05335	COG1278	Cold shock
L2Z48_05370	COG2814	Major facilitator Superfamily
L2Z48_05405	COG0517	IMP dehydrogenase activity
L2Z48_05405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z48_05410	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z48_05420	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z48_05425	COG1137	ATPase activity
L2Z48_05430	COG1538	Outer membrane efflux protein
L2Z48_05460	COG4122	O-methyltransferase activity
L2Z48_05470	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z48_05485	COG1522	sequence-specific DNA binding
L2Z48_05490	COG5006	permease, DMT superfamily
L2Z48_05500	COG1560	Kdo2-lipid A biosynthetic process
L2Z48_05535	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z48_05585	COG0583	DNA-binding transcription factor activity
L2Z48_05590	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z48_05610	COG4770	biotin carboxylase activity
L2Z48_05615	COG0038	chloride channel
L2Z48_05635	COG1309	transcriptional regulator
L2Z48_05645	COG1063	alcohol dehydrogenase
L2Z48_05660	COG0439	Biotin carboxylase
L2Z48_05665	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z48_05685	COG0864	Transcriptional regulator
L2Z48_05695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z48_05700	COG1116	anion transmembrane transporter activity
L2Z48_05820	COG0590	tRNA wobble adenosine to inosine editing
L2Z48_05825	COG2807	transmembrane transport
L2Z48_05840	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z48_05855	COG0789	Transcriptional regulator
L2Z48_05865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z48_05885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z48_05895	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z48_05910	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_05915	COG0531	amino acid
L2Z48_05920	COG1760	l-serine dehydratase
L2Z48_05925	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_05925	COG2030	dehydratase
L2Z48_05930	COG3396	Phenylacetate-CoA oxygenase
L2Z48_05935	COG3460	Phenylacetate-CoA oxygenase
L2Z48_05940	COG3396	Phenylacetate-CoA oxygenase
L2Z48_05945	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z48_05950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z48_05955	COG1024	Enoyl-CoA hydratase
L2Z48_05960	COG1024	Enoyl-CoA hydratase
L2Z48_05965	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z48_05970	COG0183	Belongs to the thiolase family
L2Z48_05975	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z48_05980	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z48_05990	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z48_06025	COG0753	catalase activity
L2Z48_06030	COG3038	cytochrome b561
L2Z48_06050	COG2267	carboxylic ester hydrolase activity
L2Z48_06055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z48_06060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z48_06065	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_06075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z48_06085	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_06090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z48_06095	COG0583	DNA-binding transcription factor activity
L2Z48_06105	COG1414	Transcriptional regulator
L2Z48_06110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z48_06120	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z48_06125	COG3842	ATPase activity
L2Z48_06140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z48_06145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z48_06150	COG2814	Major facilitator Superfamily
L2Z48_06155	COG1960	acyl-CoA dehydrogenase activity
L2Z48_06170	COG1024	Enoyl-CoA hydratase
L2Z48_06180	COG2814	Major facilitator Superfamily
L2Z48_06190	COG0183	Belongs to the thiolase family
L2Z48_06195	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z48_06200	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_06205	COG1024	Enoyl-CoA hydratase
L2Z48_06210	COG1960	acyl-CoA dehydrogenase activity
L2Z48_06215	COG2814	Major facilitator Superfamily
L2Z48_06220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z48_06225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z48_06235	COG2814	Major facilitator Superfamily
L2Z48_06245	COG1960	acyl-CoA dehydrogenase activity
L2Z48_06260	COG0583	DNA-binding transcription factor activity
L2Z48_06270	COG4770	biotin carboxylase activity
L2Z48_06275	COG1024	Enoyl-CoA hydratase
L2Z48_06280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z48_06285	COG1960	acyl-CoA dehydrogenase activity
L2Z48_06290	COG1309	transcriptional regulator
L2Z48_06295	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z48_06315	COG0583	DNA-binding transcription factor activity
L2Z48_06365	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_06385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z48_06405	COG0784	Response regulator, receiver
L2Z48_06405	COG2205	protein histidine kinase activity
L2Z48_06425	COG0765	amino acid transport
L2Z48_06430	COG0765	amino acid transport
L2Z48_06435	COG1126	abc transporter atp-binding protein
L2Z48_06440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z48_06445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z48_06460	COG1280	lysine exporter protein (LysE YggA)
L2Z48_06470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z48_06475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z48_06480	COG1045	serine acetyltransferase
L2Z48_06495	COG0583	DNA-binding transcription factor activity
L2Z48_06500	COG0625	glutathione transferase activity
L2Z48_06505	COG0625	glutathione transferase activity
L2Z48_06510	COG0583	DNA-binding transcription factor activity
L2Z48_06520	COG1346	cytolysis
L2Z48_06540	COG2814	Major facilitator Superfamily
L2Z48_06550	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z48_06555	COG3052	prosthetic group binding
L2Z48_06575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z48_06595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z48_06605	COG1294	oxidase, subunit
L2Z48_06610	COG1271	oxidase subunit
L2Z48_06640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z48_06645	COG2175	clavaminate synthase activity
L2Z48_06655	COG1953	Uracil, thiamine, allantoin
L2Z48_06665	COG0583	DNA-binding transcription factor activity
L2Z48_06675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z48_06690	COG0640	Transcriptional regulator
L2Z48_06695	COG0798	PFAM Bile acid sodium symporter
L2Z48_06700	COG0583	DNA-binding transcription factor activity
L2Z48_06715	COG3634	alkyl hydroperoxide reductase activity
L2Z48_06755	COG0436	Aminotransferase
L2Z48_06765	COG0386	Belongs to the glutathione peroxidase family
L2Z48_06805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z48_06830	COG0012	GTP binding
L2Z48_06835	COG2011	ABC-type metal ion transport system permease component
L2Z48_06840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z48_06850	COG1464	Belongs to the NlpA lipoprotein family
L2Z48_06880	COG0765	amino acid transport
L2Z48_06885	COG0765	amino acid transport
L2Z48_06890	COG1126	abc transporter atp-binding protein
L2Z48_06900	COG1522	sequence-specific DNA binding
L2Z48_06935	COG0583	DNA-binding transcription factor activity
L2Z48_06945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z48_06955	COG0697	spore germination
L2Z48_06980	COG3121	Chaperone
L2Z48_06985	COG3539	Fimbrial protein
L2Z48_07010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z48_07010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z48_07040	COG1002	Type II restriction enzyme, methylase subunits
L2Z48_07045	COG1061	Type III restriction enzyme res subunit
L2Z48_07085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z48_07095	COG2353	YceI-like domain
L2Z48_07105	COG3698	Phosphodiester glycosidase
L2Z48_07120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z48_07125	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z48_07125	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z48_07125	COG0506	proline dehydrogenase activity
L2Z48_07135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z48_07140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z48_07160	COG1132	(ABC) transporter
L2Z48_07165	COG3122	Protein conserved in bacteria
L2Z48_07170	COG3619	membrane
L2Z48_07180	COG0640	Transcriptional regulator
L2Z48_07190	COG2850	peptidyl-arginine hydroxylation
L2Z48_07195	COG0424	maF-like protein
L2Z48_07215	COG0191	fructose-bisphosphate aldolase activity
L2Z48_07220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z48_07235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z48_07245	COG1192	Involved in chromosome partitioning
L2Z48_07250	COG1475	DNA binding
L2Z48_07255	COG0811	peptide transport
L2Z48_07265	COG1132	(ABC) transporter
L2Z48_07270	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z48_07290	COG0084	hydrolase, TatD family'
L2Z48_07355	COG0776	regulation of translation
L2Z48_07385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z48_07480	COG3728	DNA packaging
L2Z48_07480	COG5484	DNA packaging
L2Z48_07595	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z48_07645	COG0339	signal peptide processing
L2Z48_07655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z48_07695	COG0702	epimerase
L2Z48_07700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z48_07720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z48_07750	COG0316	Belongs to the HesB IscA family
L2Z48_07755	COG0822	iron-sulfur transferase activity
L2Z48_07780	COG0776	regulation of translation
L2Z48_07785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z48_07790	COG2207	Transcriptional regulator
L2Z48_07795	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z48_07800	COG1960	acyl-CoA dehydrogenase activity
L2Z48_07805	COG1960	acyl-CoA dehydrogenase activity
L2Z48_07820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z48_07840	COG4264	IucA IucC family
L2Z48_07845	COG4264	IucA IucC family
L2Z48_07885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z48_07900	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z48_07920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z48_07925	COG0730	response to heat
L2Z48_07945	COG4773	Receptor
L2Z48_07950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z48_07965	COG1131	(ABC) transporter
L2Z48_07970	COG0842	Transport permease protein
L2Z48_07975	COG0842	Transport permease protein
L2Z48_08030	COG2226	methyltransferase
L2Z48_08055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z48_08095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z48_08105	COG0133	tryptophan synthase activity
L2Z48_08120	COG3706	GGDEF domain
L2Z48_08140	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z48_08145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z48_08150	COG0022	dehydrogenase e1 component
L2Z48_08155	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z48_08160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z48_08170	COG1063	alcohol dehydrogenase
L2Z48_08175	COG3781	membrane
L2Z48_08185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z48_08185	COG3453	Protein conserved in bacteria
L2Z48_08200	COG0730	response to heat
L2Z48_08215	COG2207	Transcriptional regulator
L2Z48_08215	COG3708	Transcriptional regulator
L2Z48_08220	COG1733	regulation of RNA biosynthetic process
L2Z48_08225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z48_08235	COG2188	Transcriptional regulator
L2Z48_08250	COG4521	taurine ABC transporter
L2Z48_08255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z48_08275	COG0477	Major facilitator Superfamily
L2Z48_08285	COG1027	Aspartate ammonia-lyase
L2Z48_08300	COG0583	DNA-binding transcription factor activity
L2Z48_08305	COG0583	DNA-binding transcription factor activity
L2Z48_08310	COG0183	Belongs to the thiolase family
L2Z48_08315	COG2031	fatty acid transporter
L2Z48_08320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z48_08330	COG0583	DNA-binding transcription factor activity
L2Z48_08345	COG3539	Fimbrial protein
L2Z48_08365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z48_08385	COG2072	flavoprotein involved in K transport
L2Z48_08395	COG1538	Outer membrane efflux protein
L2Z48_08400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z48_08405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z48_08410	COG0745	RESPONSE REGULATOR receiver
L2Z48_08415	COG2205	protein histidine kinase activity
L2Z48_08425	COG2207	Transcriptional regulator
L2Z48_08440	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_08495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z48_08615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z48_08645	COG1120	ATPase activity
L2Z48_08650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z48_08660	COG1064	alcohol dehydrogenase
L2Z48_08675	COG2207	Transcriptional regulator
L2Z48_08680	COG2084	Dehydrogenase
L2Z48_08690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z48_08695	COG0583	DNA-binding transcription factor activity
L2Z48_08705	COG0129	dihydroxy-acid dehydratase activity
L2Z48_08710	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_08725	COG1566	PFAM secretion protein HlyD family protein
L2Z48_08755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z48_08785	COG0583	DNA-binding transcription factor activity
L2Z48_08800	COG2188	Transcriptional regulator
L2Z48_08830	COG3210	domain, Protein
L2Z48_08835	COG2831	hemolysin activation secretion protein
L2Z48_08845	COG1473	amidohydrolase
L2Z48_08855	COG0475	glutathione-regulated potassium exporter activity
L2Z48_08855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z48_08865	COG0583	DNA-binding transcription factor activity
L2Z48_08870	COG1335	isochorismatase
L2Z48_08880	COG1309	transcriptional regulator
L2Z48_08910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z48_08920	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z48_08920	COG1902	pentaerythritol trinitrate reductase activity
L2Z48_08925	COG1846	Transcriptional regulator
L2Z48_08945	COG0753	catalase activity
L2Z48_08960	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_08975	COG3162	membrane
L2Z48_08990	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_08995	COG1960	acyl-CoA dehydrogenase activity
L2Z48_09015	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_09035	COG2186	Transcriptional regulator
L2Z48_09045	COG0583	DNA-binding transcription factor activity
L2Z48_09050	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z48_09055	COG4829	muconolactone delta-isomerase
L2Z48_09065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z48_09070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z48_09075	COG0183	Belongs to the thiolase family
L2Z48_09080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z48_09090	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_09100	COG3733	amine oxidase
L2Z48_09110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z48_09120	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_09130	COG4638	Rieske (2fe-2S)
L2Z48_09150	COG0154	amidase activity
L2Z48_09160	COG2814	Major facilitator Superfamily
L2Z48_09185	COG1960	acyl-CoA dehydrogenase activity
L2Z48_09190	COG0583	DNA-binding transcription factor activity
L2Z48_09195	COG1414	Transcriptional regulator
L2Z48_09210	COG2391	methyltransferase activity
L2Z48_09220	COG4993	Dehydrogenase
L2Z48_09225	COG3659	wide pore channel activity
L2Z48_09230	COG3420	alginic acid biosynthetic process
L2Z48_09235	COG0710	3-dehydroquinate dehydratase activity
L2Z48_09240	COG3485	protocatechuate 3,4-dioxygenase
L2Z48_09245	COG3485	protocatechuate 3,4-dioxygenase
L2Z48_09250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z48_09255	COG2271	Major facilitator Superfamily
L2Z48_09260	COG0596	Alpha beta hydrolase
L2Z48_09265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z48_09270	COG0183	Belongs to the thiolase family
L2Z48_09275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z48_09280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z48_09290	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z48_09295	COG2323	membrane
L2Z48_09340	COG1902	pentaerythritol trinitrate reductase activity
L2Z48_09340	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z48_09365	COG0542	response to heat
L2Z48_09370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z48_09400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z48_09405	COG0569	domain protein
L2Z48_09410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z48_09425	COG4774	siderophore transport
L2Z48_09430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z48_09440	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z48_09460	COG1294	oxidase, subunit
L2Z48_09465	COG4890	Cyd operon protein YbgT
L2Z48_09480	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z48_09490	COG0552	protein localization to endoplasmic reticulum
L2Z48_09515	COG0517	IMP dehydrogenase activity
L2Z48_09515	COG0516	GMP reductase activity
L2Z48_09520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z48_09525	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z48_09535	COG0583	DNA-binding transcription factor activity
L2Z48_09540	COG0024	Methionine aminopeptidase
L2Z48_09570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z48_09570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z48_09575	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z48_09580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z48_09580	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z48_09580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z48_09600	COG5001	Diguanylate cyclase
L2Z48_09600	COG3300	MHYT domain
L2Z48_09615	COG2135	peptidase activity
L2Z48_09620	COG0659	secondary active sulfate transmembrane transporter activity
L2Z48_09640	COG1113	amino acid transport
L2Z48_09650	COG1522	sequence-specific DNA binding
L2Z48_09675	COG1011	Hydrolase
L2Z48_09680	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z48_09690	COG2137	regulation of response to DNA damage stimulus
L2Z48_09705	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z48_09740	COG0575	Belongs to the CDS family
L2Z48_09745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z48_09765	COG3852	Histidine kinase
L2Z48_09770	COG2204	response regulator
L2Z48_09825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z48_09830	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z48_09850	COG0697	spore germination
L2Z48_09855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z48_09865	COG0303	'Molybdopterin
L2Z48_09870	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z48_09870	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z48_09885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z48_09890	COG0243	molybdopterin cofactor binding
L2Z48_09900	COG0243	molybdopterin cofactor binding
L2Z48_09905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z48_09910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z48_09910	COG2146	nitrite reductase [NAD(P)H] activity
L2Z48_09920	COG0745	RESPONSE REGULATOR receiver
L2Z48_09925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z48_09925	COG1116	anion transmembrane transporter activity
L2Z48_09945	COG0511	ligase activity, forming carbon-carbon bonds
L2Z48_09960	COG2814	Major facilitator Superfamily
L2Z48_10295	COG0069	glutamate synthase activity
L2Z48_10315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z48_10325	COG1454	alcohol dehydrogenase
L2Z48_10330	COG0824	Thioesterase
L2Z48_10340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z48_10355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z48_10360	COG2030	dehydratase
L2Z48_10370	COG0183	Belongs to the thiolase family
L2Z48_10380	COG0583	DNA-binding transcription factor activity
L2Z48_10385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z48_10395	COG1522	sequence-specific DNA binding
L2Z48_10400	COG3135	benzoate transporter
L2Z48_10410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z48_10435	COG0589	response to stress
L2Z48_10440	COG0488	(ABC) transporter
L2Z48_10460	COG4773	Receptor
L2Z48_10490	COG0668	transmembrane transport
L2Z48_10500	COG1309	transcriptional regulator
L2Z48_10520	COG1605	Chorismate mutase
L2Z48_10530	COG4221	oxidoreductase activity
L2Z48_10540	COG0308	aminopeptidase N
L2Z48_10560	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z48_10570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z48_10575	COG1454	alcohol dehydrogenase
L2Z48_10595	COG0531	amino acid
L2Z48_10600	COG4303	Ethanolamine ammonia lyase large subunit
L2Z48_10605	COG4302	ethanolamine ammonia-lyase activity
L2Z48_10610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z48_10610	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z48_10615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z48_10625	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z48_10640	COG0697	spore germination
L2Z48_10645	COG1923	regulation of RNA biosynthetic process
L2Z48_10655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z48_10660	COG0802	atpase or kinase
L2Z48_10680	COG1187	pseudouridine synthase activity
L2Z48_10695	COG0583	DNA-binding transcription factor activity
L2Z48_10710	COG2814	Major facilitator Superfamily
L2Z48_10715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z48_10740	COG0729	surface antigen
L2Z48_10760	COG0174	glutamine synthetase
L2Z48_10765	COG0745	RESPONSE REGULATOR receiver
L2Z48_10770	COG2205	protein histidine kinase activity
L2Z48_10780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z48_10785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z48_10810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z48_10815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z48_10820	COG1960	acyl-CoA dehydrogenase activity
L2Z48_10835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z48_10840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z48_10860	COG0583	DNA-binding transcription factor activity
L2Z48_10875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z48_10885	COG3658	cytochrome
L2Z48_10890	COG1215	transferase activity, transferring glycosyl groups
L2Z48_10895	COG0726	polysaccharide deacetylase
L2Z48_10895	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z48_10920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z48_10925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z48_10935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z48_10960	COG0305	Participates in initiation and elongation during chromosome replication
L2Z48_10965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z48_10975	COG1305	Transglutaminase-like
L2Z48_10985	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z48_11015	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z48_11020	COG0138	bifunctional purine biosynthesis protein purh
L2Z48_11025	COG0151	Belongs to the GarS family
L2Z48_11030	COG1464	Belongs to the NlpA lipoprotein family
L2Z48_11035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z48_11040	COG2011	ABC-type metal ion transport system permease component
L2Z48_11045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z48_11055	COG1301	dicarboxylic acid transport
L2Z48_11085	COG1794	racemase activity, acting on amino acids and derivatives
L2Z48_11095	COG3008	intermembrane lipid transfer
L2Z48_11095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z48_11100	COG2995	paraquat-inducible protein a
L2Z48_11110	COG2985	domain, Protein
L2Z48_11140	COG0477	Major facilitator Superfamily
L2Z48_11200	COG2186	Transcriptional regulator
L2Z48_11210	COG0786	glutamate:sodium symporter activity
L2Z48_11215	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z48_11345	COG1610	YqeY-like protein
L2Z48_11350	COG4783	chaperone-mediated protein folding
L2Z48_11375	COG1286	toxin biosynthetic process
L2Z48_11405	COG0778	Nitroreductase
L2Z48_11415	COG0513	Belongs to the DEAD box helicase family
L2Z48_11440	COG2363	Small membrane protein
L2Z48_11470	COG1234	tRNA 3'-trailer cleavage
L2Z48_11475	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z48_11485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z48_11495	COG2819	hydrolase of the alpha beta superfamily
L2Z48_11500	COG1960	acyl-CoA dehydrogenase activity
L2Z48_11505	COG1301	dicarboxylic acid transport
L2Z48_11510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z48_11515	COG3139	Protein of unknown function (DUF1315)
L2Z48_11520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z48_11525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z48_11535	COG0494	nUDIX hydrolase
L2Z48_11545	COG0642	Histidine kinase
L2Z48_11560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z48_11570	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z48_11585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z48_11590	COG0826	peptidase U32
L2Z48_11595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z48_11605	COG4598	ABC transporter
L2Z48_11610	COG4160	amino acid transport
L2Z48_11615	COG4215	(ABC) transporter
L2Z48_11630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z48_11675	COG1131	(ABC) transporter
L2Z48_11680	COG0842	Transport permease protein
L2Z48_11695	COG0772	Belongs to the SEDS family
L2Z48_11700	COG2951	lytic endotransglycosylase activity
L2Z48_11725	COG2207	Transcriptional regulator
L2Z48_11740	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z48_11745	COG0024	Methionine aminopeptidase
L2Z48_11755	COG2223	nitrite transmembrane transporter activity
L2Z48_11765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z48_11770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z48_11775	COG1960	acyl-CoA dehydrogenase activity
L2Z48_11790	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z48_11795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z48_11800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z48_11820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z48_11825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z48_11830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z48_11865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z48_11875	COG0174	glutamine synthetase
L2Z48_11890	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z48_11895	COG0308	aminopeptidase N
L2Z48_11925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z48_11935	COG0302	gtp cyclohydrolase
L2Z48_11960	COG3739	integral membrane protein
L2Z48_11975	COG1169	isochorismate synthase
L2Z48_11985	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z48_11990	COG1132	(ABC) transporter
L2Z48_11995	COG1132	(ABC) transporter
L2Z48_12010	COG1535	isochorismatase
L2Z48_12010	COG3433	isochorismatase activity
L2Z48_12015	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z48_12020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z48_12030	COG4774	siderophore transport
L2Z48_12035	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z48_12040	COG4604	ABC transporter, ATP-binding protein
L2Z48_12045	COG4605	iron ion homeostasis
L2Z48_12050	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z48_12055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z48_12070	COG2964	Protein conserved in bacteria
L2Z48_12080	COG1741	Belongs to the pirin family
L2Z48_12100	COG1309	transcriptional regulator
L2Z48_12110	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z48_12115	COG2814	Major facilitator Superfamily
L2Z48_12150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z48_12150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z48_12155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z48_12165	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_12175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z48_12180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z48_12185	COG0583	DNA-binding transcription factor activity
L2Z48_12190	COG1113	amino acid transport
L2Z48_12210	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z48_12210	COG2508	Transcriptional regulator
L2Z48_12245	COG2879	small protein
L2Z48_12250	COG1966	Carbon starvation protein
L2Z48_12295	COG1067	ATP-dependent peptidase activity
L2Z48_12300	COG0583	DNA-binding transcription factor activity
L2Z48_12325	COG1686	Belongs to the peptidase S11 family
L2Z48_12330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z48_12365	COG0616	signal peptide processing
L2Z48_12370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z48_12380	COG0573	inorganic phosphate transmembrane transporter activity
L2Z48_12385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z48_12390	COG1113	amino acid transport
L2Z48_12395	COG3961	Belongs to the TPP enzyme family
L2Z48_12400	COG1522	sequence-specific DNA binding
L2Z48_12410	COG0076	glutamate decarboxylase activity
L2Z48_12415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z48_12430	COG1309	transcriptional regulator
L2Z48_12445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z48_12480	COG0352	thiamine-phosphate diphosphorylase activity
L2Z48_12505	COG0612	Peptidase, M16
L2Z48_12515	COG1823	symporter activity
L2Z48_12520	COG0583	DNA-binding transcription factor activity
L2Z48_12525	COG0477	Major facilitator Superfamily
L2Z48_12550	COG1187	pseudouridine synthase activity
L2Z48_12565	COG1686	Belongs to the peptidase S11 family
L2Z48_12570	COG1252	NADH dehydrogenase
L2Z48_12580	COG0415	Belongs to the DNA photolyase family
L2Z48_12595	COG1215	transferase activity, transferring glycosyl groups
L2Z48_12625	COG2070	2-Nitropropane dioxygenase
L2Z48_12815	COG5410	chromosome segregation
L2Z48_13015	COG0556	nucleotide-excision repair
L2Z48_13035	COG0436	Aminotransferase
L2Z48_13065	COG4221	oxidoreductase activity
L2Z48_13075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z48_13080	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z48_13090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z48_13105	COG0681	Belongs to the peptidase S26 family
L2Z48_13120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z48_13140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z48_13145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z48_13150	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z48_13160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z48_13165	COG4208	sulfate ABC transporter
L2Z48_13170	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z48_13175	COG0583	DNA-binding transcription factor activity
L2Z48_13180	COG4625	pathogenesis
L2Z48_13195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z48_13210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z48_13220	COG1056	cytidyltransferase-related domain
L2Z48_13220	COG1051	belongs to the nudix hydrolase family
L2Z48_13225	COG1024	Enoyl-CoA hydratase
L2Z48_13235	COG2814	Major facilitator Superfamily
L2Z48_13240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z48_13240	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z48_13260	COG1473	amidohydrolase
L2Z48_13265	COG0824	Thioesterase
L2Z48_13285	COG0823	Involved in the tonB-independent uptake of proteins
L2Z48_13305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z48_13340	COG0628	permease
L2Z48_13350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z48_13355	COG0596	Alpha beta hydrolase
L2Z48_13360	COG0616	signal peptide processing
L2Z48_13360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z48_13370	COG0658	competence protein
L2Z48_13370	COG2333	competence protein COMEC
L2Z48_13375	COG1136	(ABC) transporter
L2Z48_13380	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z48_13420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z48_13440	COG0463	Glycosyl transferase, family 2
L2Z48_13470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z48_13475	COG1280	lysine exporter protein (LysE YggA)
L2Z48_13485	COG0019	diaminopimelate decarboxylase activity
L2Z48_13495	COG1113	amino acid transport
L2Z48_13510	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z48_13520	COG3339	Conserved Protein
L2Z48_13525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z48_13530	COG0243	molybdopterin cofactor binding
L2Z48_13535	COG1929	Belongs to the glycerate kinase type-1 family
L2Z48_13550	COG0778	Nitroreductase
L2Z48_13590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z48_13605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z48_13625	COG0741	lytic transglycosylase activity
L2Z48_13645	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z48_13650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z48_13675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z48_13680	COG1597	lipid kinase activity
L2Z48_13695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z48_13700	COG0477	Major facilitator Superfamily
L2Z48_13750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z48_13755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z48_13780	COG0505	Belongs to the CarA family
L2Z48_13800	COG0589	response to stress
L2Z48_13815	COG2843	Capsule synthesis protein
L2Z48_13835	COG2321	neutral zinc metallopeptidase
L2Z48_13840	COG2354	Protein conserved in bacteria
L2Z48_13860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z48_13885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z48_13890	COG1053	succinate dehydrogenase
L2Z48_13895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z48_13900	COG2009	succinate dehydrogenase
L2Z48_13945	COG2921	Belongs to the UPF0250 family
L2Z48_13950	COG0321	lipoyl(octanoyl) transferase activity
L2Z48_13965	COG0531	amino acid
L2Z48_13975	COG1733	regulation of RNA biosynthetic process
L2Z48_13980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z48_13985	COG1648	precorrin-2 dehydrogenase activity
L2Z48_13985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z48_14000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z48_14030	COG0671	phosphoesterase, PA-phosphatase related
L2Z48_14035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z48_14045	COG1538	Outer membrane efflux protein
L2Z48_14050	COG0393	Putative heavy-metal-binding
L2Z48_14055	COG0393	Putative heavy-metal-binding
L2Z48_14065	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_14075	COG0525	valine-tRNA ligase activity
L2Z48_14095	COG0583	DNA-binding transcription factor activity
L2Z48_14100	COG0004	ammonium transporteR
L2Z48_14110	COG0642	Histidine kinase
L2Z48_14115	COG0745	RESPONSE REGULATOR receiver
L2Z48_14120	COG2194	sulfuric ester hydrolase activity
L2Z48_14140	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z48_14155	COG2315	Protein conserved in bacteria
L2Z48_14160	COG0142	geranyltranstransferase activity
L2Z48_14165	COG2828	Protein conserved in bacteria
L2Z48_14170	COG1113	amino acid transport
L2Z48_14190	COG2207	Transcriptional regulator
L2Z48_14215	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z48_14225	COG0560	Phosphoserine phosphatase
L2Z48_14235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z48_14245	COG1530	ribonuclease E activity
L2Z48_14250	COG0424	maF-like protein
L2Z48_14255	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z48_14260	COG1792	Involved in formation and maintenance of cell shape
L2Z48_14265	COG1077	Cell shape determining protein MreB Mrl
L2Z48_14270	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z48_14280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z48_14315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z48_14320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z48_14325	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z48_14330	COG1115	amino acid carrier protein
L2Z48_14350	COG2814	Major facilitator Superfamily
L2Z48_14355	COG1289	transmembrane transporter activity
L2Z48_14365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z48_14405	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z48_14410	COG2832	Protein of unknown function (DUF454)
L2Z48_14420	COG5510	response to toxic substance
L2Z48_14440	COG0840	transmembrane signaling receptor activity
L2Z48_14480	COG3422	double-strand break repair
L2Z48_14485	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z48_14490	COG3189	MarR family transcriptional regulator
L2Z48_14500	COG0354	folic acid binding
L2Z48_14505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z48_14515	COG0679	Auxin Efflux Carrier
L2Z48_14520	COG1902	pentaerythritol trinitrate reductase activity
L2Z48_14525	COG4772	TonB-dependent receptor
L2Z48_14530	COG2094	Belongs to the DNA glycosylase MPG family
L2Z48_14555	COG1217	gtp-binding protein TYPA
L2Z48_14560	COG2233	PERMEase
L2Z48_14570	COG0833	amino acid
L2Z48_14575	COG1690	Belongs to the RtcB family
L2Z48_14585	COG2885	chlorophyll binding
L2Z48_14585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z48_14595	COG0183	Belongs to the thiolase family
L2Z48_14615	COG1061	Type III restriction enzyme res subunit
L2Z48_14620	COG1002	Type II restriction enzyme, methylase subunits
L2Z48_14645	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z48_14665	COG2207	Transcriptional regulator
L2Z48_14670	COG0183	Belongs to the thiolase family
L2Z48_14700	COG1272	protein, Hemolysin III
L2Z48_14705	COG0477	Major facilitator Superfamily
L2Z48_14725	COG0450	alkyl hydroperoxide reductase
L2Z48_14745	COG0285	dihydrofolate synthase activity
L2Z48_14795	COG2096	Adenosyltransferase
L2Z48_14815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z48_14820	COG0745	RESPONSE REGULATOR receiver
L2Z48_14825	COG2205	protein histidine kinase activity
L2Z48_14835	COG1960	acyl-CoA dehydrogenase activity
L2Z48_14840	COG1960	acyl-CoA dehydrogenase activity
L2Z48_14845	COG0583	DNA-binding transcription factor activity
L2Z48_14850	COG0625	glutathione transferase activity
L2Z48_14915	COG0438	transferase activity, transferring glycosyl groups
L2Z48_14920	COG0463	Glycosyl transferase, family 2
L2Z48_14925	COG0726	polysaccharide deacetylase
L2Z48_14945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z48_14950	COG2205	protein histidine kinase activity
L2Z48_15010	COG1862	Preprotein translocase
L2Z48_15020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z48_15025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z48_15035	COG3781	membrane
L2Z48_15040	COG0613	PHP domain protein
L2Z48_15050	COG2350	Protein conserved in bacteria
L2Z48_15080	COG1607	acyl-coa hydrolase
L2Z48_15140	COG2199	diguanylate cyclase activity
L2Z48_15150	COG1408	metallophosphoesterase
L2Z48_15155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z48_15165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z48_15275	COG0739	heme binding
L2Z48_15405	COG5410	chromosome segregation
L2Z48_15570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z48_15575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z48_15590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z48_15600	COG2969	positive regulation of protein catabolic process
L2Z48_15620	COG1960	acyl-CoA dehydrogenase activity
L2Z48_15625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z48_15640	COG1309	transcriptional regulator
L2Z48_15645	COG1960	acyl-CoA dehydrogenase activity
L2Z48_15690	COG1183	phosphatidylcholine synthase activity
L2Z48_15695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z48_15725	COG0741	lytic transglycosylase activity
L2Z48_15725	COG1196	nuclear chromosome segregation
L2Z48_15725	COG0739	heme binding
L2Z48_15735	COG1702	phosphate starvation-inducible protein PhoH
L2Z48_15770	COG1295	ribonuclease BN
L2Z48_15775	COG0697	spore germination
L2Z48_15780	COG2169	Transcriptional regulator
L2Z48_15785	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z48_15830	COG0557	exoribonuclease II activity
L2Z48_15835	COG0339	signal peptide processing
L2Z48_15840	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z48_15870	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z48_15875	COG1960	acyl-CoA dehydrogenase activity
L2Z48_16030	COG0626	cystathionine gamma-synthase activity
L2Z48_16035	COG0433	COG0433 Predicted ATPase
L2Z48_16040	COG1017	nitric oxide dioxygenase activity
L2Z48_16040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z48_16045	COG1959	2 iron, 2 sulfur cluster binding
L2Z48_16060	COG1301	dicarboxylic acid transport
L2Z48_16065	COG1946	Acyl-CoA thioesterase
L2Z48_16085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z48_16090	COG1040	competence protein
L2Z48_16095	COG0494	nUDIX hydrolase
L2Z48_16105	COG0598	Magnesium transport protein CorA
L2Z48_16115	COG2854	intermembrane phospholipid transfer
L2Z48_16125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z48_16130	COG1127	ABC transporter
L2Z48_16140	COG0513	Belongs to the DEAD box helicase family
L2Z48_16160	COG0408	coproporphyrinogen oxidase activity
L2Z48_16175	COG1960	acyl-CoA dehydrogenase activity
L2Z48_16185	COG1983	PspC domain protein
L2Z48_16190	COG0517	IMP dehydrogenase activity
L2Z48_16235	COG0583	DNA-binding transcription factor activity
L2Z48_16275	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_16285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z48_16290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z48_16295	COG0833	amino acid
L2Z48_16330	COG1192	Involved in chromosome partitioning
L2Z48_16335	COG0628	permease
L2Z48_16345	COG1289	transmembrane transporter activity
L2Z48_16360	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z48_16365	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z48_16375	COG0277	FAD linked oxidase domain protein
L2Z48_16380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z48_16405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z48_16410	COG5380	lipid catabolic process
L2Z48_16430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z48_16480	COG0194	GDP metabolic process
L2Z48_16495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z48_16515	COG3307	-O-antigen
L2Z48_16535	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z48_16540	COG1704	LemA family
L2Z48_16550	COG0493	'glutamate synthase
L2Z48_16555	COG0070	glutamate synthase
L2Z48_16555	COG0069	glutamate synthase activity
L2Z48_16555	COG0067	glutamate synthase
L2Z48_16605	COG2226	methyltransferase
L2Z48_16620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z48_16625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z48_16670	COG0833	amino acid
L2Z48_16755	COG0488	(ABC) transporter
L2Z48_16760	COG2873	o-acetylhomoserine
L2Z48_16765	COG4221	oxidoreductase activity
L2Z48_16770	COG0659	secondary active sulfate transmembrane transporter activity
L2Z48_16795	COG0427	acetyl-CoA hydrolase
L2Z48_16825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z48_16855	COG2329	Antibiotic biosynthesis monooxygenase
L2Z48_16870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z48_16935	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z48_16940	COG1733	regulation of RNA biosynthetic process
L2Z48_16975	COG0667	Aldo Keto reductase
L2Z48_16995	COG0583	DNA-binding transcription factor activity
L2Z48_17000	COG2814	Major facilitator Superfamily
L2Z48_17030	COG1335	isochorismatase
L2Z48_17040	COG1012	belongs to the aldehyde dehydrogenase family
L2Z48_17045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z48_17055	COG1113	amino acid transport
L2Z48_17065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z48_17080	COG2814	Major facilitator Superfamily
L2Z48_17090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z48_17090	COG0352	thiamine-phosphate diphosphorylase activity
L2Z48_17090	COG0351	phosphomethylpyrimidine kinase
L2Z48_17110	COG1309	transcriptional regulator
L2Z48_17115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z48_17135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z48_17145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z48_17150	COG3162	membrane
L2Z48_17155	COG0784	Response regulator, receiver
L2Z48_17155	COG2198	Histidine kinase
L2Z48_17155	COG2205	protein histidine kinase activity
L2Z48_17180	COG3328	transposase activity
L2Z48_17185	COG1522	sequence-specific DNA binding
L2Z48_17190	COG1335	isochorismatase
L2Z48_17195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z48_17205	COG0668	transmembrane transport
L2Z48_17210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z48_17215	COG1519	Transferase
L2Z48_17220	COG1902	pentaerythritol trinitrate reductase activity
L2Z48_17240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z48_17265	COG0426	domain, Protein
L2Z48_17265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z48_17270	COG4774	siderophore transport
L2Z48_17275	COG2119	membrane
L2Z48_17285	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z48_17295	COG4942	peptidase
L2Z48_17310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z48_17320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z48_17340	COG0189	ligase activity
L2Z48_17360	COG0708	Exodeoxyribonuclease III
L2Z48_17365	COG1393	Belongs to the ArsC family
L2Z48_17380	COG3706	GGDEF domain
L2Z48_17415	COG2351	hydroxyisourate hydrolase activity
L2Z48_17420	COG2233	PERMEase
L2Z48_17430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z48_17440	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z48_17445	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_17455	COG3150	esterase
L2Z48_17485	COG2918	glutathione biosynthetic process
L2Z48_17500	COG2733	membrane
L2Z48_17505	COG0436	Aminotransferase
L2Z48_17515	COG0534	Mate efflux family protein
L2Z48_17615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z48_17620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z48_17630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z48_17635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z48_17650	COG0010	Belongs to the arginase family
L2Z48_17680	COG2188	Transcriptional regulator
L2Z48_17690	COG0523	cobalamin synthesis protein
L2Z48_17700	COG1113	amino acid transport
L2Z48_17710	COG0625	glutathione transferase activity
L2Z48_17730	COG1683	Conserved Protein
L2Z48_17735	COG0534	Mate efflux family protein
L2Z48_17740	COG0385	Bile acid
L2Z48_17745	COG1335	isochorismatase
L2Z48_17750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z48_17770	COG2116	formate transmembrane transporter activity
L2Z48_17775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z48_17780	COG2133	pyrroloquinoline quinone binding
L2Z48_17785	COG2983	Belongs to the UPF0260 family
L2Z48_17805	COG1194	a g-specific adenine glycosylase
L2Z48_17820	COG2818	Glycosylase
L2Z48_17825	COG1064	alcohol dehydrogenase
L2Z48_17830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z48_17845	COG0583	DNA-binding transcription factor activity
L2Z48_17850	COG0656	L-ascorbic acid biosynthetic process
L2Z48_17855	COG2814	Major facilitator Superfamily
L2Z48_17890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z48_17905	COG2233	PERMEase
L2Z48_17945	COG0733	neurotransmitter:sodium symporter activity
L2Z48_17985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z48_17990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z48_17995	COG0596	Alpha beta hydrolase
L2Z48_18020	COG0488	(ABC) transporter
L2Z48_18025	COG0586	Pfam SNARE associated Golgi protein
L2Z48_18035	COG0187	DNA topoisomerase II activity
L2Z48_18045	COG0592	DNA-directed DNA polymerase activity
L2Z48_18070	COG0706	membrane insertase activity
L2Z48_18085	COG1230	cation diffusion facilitator family transporter
L2Z48_18090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z48_18105	COG0402	S-adenosylhomocysteine deaminase activity
L2Z48_18115	COG0754	glutathionylspermidine amidase activity
L2Z48_18125	COG0861	Integral membrane protein TerC family
L2Z48_18130	COG0671	phosphoesterase, PA-phosphatase related
L2Z48_18140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z48_18155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z48_18160	COG2951	lytic endotransglycosylase activity
L2Z48_18190	COG0583	DNA-binding transcription factor activity
L2Z48_18210	COG0657	acetylesterase activity
L2Z48_18215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z48_18255	COG1047	Peptidyl-prolyl cis-trans
L2Z48_18265	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z48_18270	COG0196	riboflavin kinase activity
L2Z48_18280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z48_18285	COG1309	transcriptional regulator
L2Z48_18290	COG1116	anion transmembrane transporter activity
L2Z48_18295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z48_18300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z48_18305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z48_18310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z48_18330	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z48_18335	COG0546	phosphoglycolate phosphatase activity
L2Z48_18395	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z48_18400	COG0728	peptidoglycan biosynthetic process
L2Z48_18425	COG1596	polysaccharide export
L2Z48_18430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z48_18435	COG1086	Polysaccharide biosynthesis protein
L2Z48_18440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L2Z48_18445	COG1083	cytidylyl-transferase
L2Z48_18460	COG2089	acid synthase
L2Z48_18490	COG1216	Glycosyl transferase, family 2
L2Z48_18495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2Z48_18500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z48_18515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z48_18520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z48_18530	COG2186	Transcriptional regulator
L2Z48_18540	COG0277	FAD linked oxidase domain protein
L2Z48_18545	COG1448	Aminotransferase
L2Z48_18555	COG1802	Transcriptional regulator
L2Z48_18570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z48_18630	COG0564	pseudouridine synthase activity
L2Z48_18670	COG0251	oxidation-reduction process
L2Z48_18675	COG1113	amino acid transport
L2Z48_18680	COG1113	amino acid transport
L2Z48_18700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z48_18705	COG1960	acyl-CoA dehydrogenase activity
L2Z48_18710	COG1024	Enoyl-CoA hydratase
L2Z48_18715	COG1024	Enoyl-CoA hydratase
L2Z48_18720	COG0477	Major facilitator Superfamily
L2Z48_18725	COG3916	Acyl-homoserine-lactone synthase
L2Z48_18735	COG2197	response regulator
L2Z48_18745	COG1960	acyl-CoA dehydrogenase activity
L2Z48_18750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z48_18750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z48_18750	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z48_18750	COG3321	synthase
L2Z48_18770	COG2267	carboxylic ester hydrolase activity
L2Z48_18785	COG0271	Belongs to the BolA IbaG family
L2Z48_18795	COG1192	Involved in chromosome partitioning
L2Z48_18810	COG0586	Pfam SNARE associated Golgi protein
L2Z48_18815	COG2259	Doxx family
L2Z48_18820	COG4399	Belongs to the UPF0754 family
L2Z48_18825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z48_18825	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z48_18870	COG0281	malic enzyme
L2Z48_18880	COG2837	iron assimilation
L2Z48_18885	COG1280	lysine exporter protein (LysE YggA)
L2Z48_18890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z48_18895	COG1121	(ABC) transporter
L2Z48_18960	COG0386	Belongs to the glutathione peroxidase family
L2Z48_18975	COG1309	transcriptional regulator
L2Z48_18980	COG0697	spore germination
L2Z48_18990	COG0758	DNA mediated transformation
L2Z48_19060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z48_19070	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z48_19110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z48_19130	COG1253	flavin adenine dinucleotide binding
L2Z48_19140	COG2860	membrane
L2Z48_19145	COG0477	Major facilitator Superfamily
L2Z48_19155	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z48_19170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z48_19190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z48_19200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z48_19235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate