locus-tag	class	description
K9O37_00010	COG0592	DNA-directed DNA polymerase activity
K9O37_00020	COG0187	DNA topoisomerase II activity
K9O37_00030	COG0586	Pfam SNARE associated Golgi protein
K9O37_00035	COG0488	(ABC) transporter
K9O37_00060	COG0596	Alpha beta hydrolase
K9O37_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K9O37_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K9O37_00110	COG0733	neurotransmitter:sodium symporter activity
K9O37_00145	COG0583	DNA-binding transcription factor activity
K9O37_00150	COG2233	PERMEase
K9O37_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9O37_00200	COG2814	Major facilitator Superfamily
K9O37_00205	COG0656	L-ascorbic acid biosynthetic process
K9O37_00210	COG0583	DNA-binding transcription factor activity
K9O37_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9O37_00230	COG1064	alcohol dehydrogenase
K9O37_00235	COG2818	Glycosylase
K9O37_00250	COG1194	a g-specific adenine glycosylase
K9O37_00270	COG2983	Belongs to the UPF0260 family
K9O37_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K9O37_00285	COG2116	formate transmembrane transporter activity
K9O37_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9O37_00310	COG1335	isochorismatase
K9O37_00315	COG0385	Bile acid
K9O37_00320	COG0534	Mate efflux family protein
K9O37_00325	COG1683	Conserved Protein
K9O37_00350	COG0625	glutathione transferase activity
K9O37_00360	COG1113	amino acid transport
K9O37_00370	COG0523	cobalamin synthesis protein
K9O37_00380	COG2188	Transcriptional regulator
K9O37_00410	COG0010	Belongs to the arginase family
K9O37_00455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K9O37_00475	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
K9O37_00505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K9O37_00515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K9O37_00520	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K9O37_00565	COG0753	catalase activity
K9O37_00615	COG0534	Mate efflux family protein
K9O37_00620	COG0436	Aminotransferase
K9O37_00625	COG2733	membrane
K9O37_00640	COG2918	glutathione biosynthetic process
K9O37_00670	COG3150	esterase
K9O37_00680	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_00685	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
K9O37_00695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9O37_00705	COG2233	PERMEase
K9O37_00710	COG2351	hydroxyisourate hydrolase activity
K9O37_00745	COG3706	GGDEF domain
K9O37_00760	COG1393	Belongs to the ArsC family
K9O37_00765	COG0708	Exodeoxyribonuclease III
K9O37_00785	COG0189	ligase activity
K9O37_00805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K9O37_00815	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K9O37_00830	COG4942	peptidase
K9O37_00840	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9O37_00850	COG2119	membrane
K9O37_00855	COG4774	siderophore transport
K9O37_00860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9O37_00860	COG0426	domain, Protein
K9O37_00885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K9O37_00905	COG1902	pentaerythritol trinitrate reductase activity
K9O37_00910	COG1519	Transferase
K9O37_00920	COG0668	transmembrane transport
K9O37_00930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9O37_00935	COG1335	isochorismatase
K9O37_00940	COG1522	sequence-specific DNA binding
K9O37_00965	COG0784	Response regulator, receiver
K9O37_00965	COG2198	Histidine kinase
K9O37_00965	COG2205	protein histidine kinase activity
K9O37_00970	COG3162	membrane
K9O37_00975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9O37_00985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9O37_01000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K9O37_01005	COG1309	transcriptional regulator
K9O37_01025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K9O37_01025	COG0352	thiamine-phosphate diphosphorylase activity
K9O37_01025	COG0351	phosphomethylpyrimidine kinase
K9O37_01035	COG2814	Major facilitator Superfamily
K9O37_01050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K9O37_01060	COG1113	amino acid transport
K9O37_01070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K9O37_01075	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_01085	COG1335	isochorismatase
K9O37_01115	COG2814	Major facilitator Superfamily
K9O37_01120	COG0583	DNA-binding transcription factor activity
K9O37_01140	COG0667	Aldo Keto reductase
K9O37_01175	COG3328	transposase activity
K9O37_01230	COG2814	Major facilitator Superfamily
K9O37_01265	COG0582	viral genome integration into host DNA
K9O37_01320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K9O37_01360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K9O37_01390	COG0427	acetyl-CoA hydrolase
K9O37_01415	COG0659	secondary active sulfate transmembrane transporter activity
K9O37_01420	COG4221	oxidoreductase activity
K9O37_01430	COG0488	(ABC) transporter
K9O37_01525	COG0833	amino acid
K9O37_01570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K9O37_01575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K9O37_01590	COG2226	methyltransferase
K9O37_01640	COG0067	glutamate synthase
K9O37_01640	COG0069	glutamate synthase activity
K9O37_01640	COG0070	glutamate synthase
K9O37_01645	COG0493	'glutamate synthase
K9O37_01655	COG1704	LemA family
K9O37_01660	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
K9O37_01680	COG3307	-O-antigen
K9O37_01700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9O37_01715	COG0194	GDP metabolic process
K9O37_01765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K9O37_01785	COG5380	lipid catabolic process
K9O37_01790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K9O37_01815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9O37_01820	COG0277	FAD linked oxidase domain protein
K9O37_01830	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
K9O37_01835	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9O37_01850	COG1289	transmembrane transporter activity
K9O37_01860	COG0628	permease
K9O37_01865	COG1192	Involved in chromosome partitioning
K9O37_01895	COG0833	amino acid
K9O37_01900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K9O37_01905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9O37_01915	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_01960	COG0583	DNA-binding transcription factor activity
K9O37_02030	COG0517	IMP dehydrogenase activity
K9O37_02035	COG1983	PspC domain protein
K9O37_02045	COG1960	acyl-CoA dehydrogenase activity
K9O37_02060	COG0408	coproporphyrinogen oxidase activity
K9O37_02080	COG0513	Belongs to the DEAD box helicase family
K9O37_02090	COG1127	ABC transporter
K9O37_02095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K9O37_02105	COG2854	intermembrane phospholipid transfer
K9O37_02115	COG0598	Magnesium transport protein CorA
K9O37_02125	COG0494	nUDIX hydrolase
K9O37_02130	COG1040	competence protein
K9O37_02135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K9O37_02155	COG1946	Acyl-CoA thioesterase
K9O37_02160	COG1301	dicarboxylic acid transport
K9O37_02175	COG1959	2 iron, 2 sulfur cluster binding
K9O37_02180	COG1017	nitric oxide dioxygenase activity
K9O37_02180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9O37_02190	COG0433	COG0433 Predicted ATPase
K9O37_02195	COG0626	cystathionine gamma-synthase activity
K9O37_02350	COG1960	acyl-CoA dehydrogenase activity
K9O37_02355	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
K9O37_02385	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
K9O37_02390	COG0339	signal peptide processing
K9O37_02395	COG0557	exoribonuclease II activity
K9O37_02440	COG0179	Fumarylacetoacetate (FAA) hydrolase
K9O37_02445	COG2169	Transcriptional regulator
K9O37_02450	COG0697	spore germination
K9O37_02455	COG1295	ribonuclease BN
K9O37_02490	COG1702	phosphate starvation-inducible protein PhoH
K9O37_02500	COG0741	lytic transglycosylase activity
K9O37_02500	COG1196	nuclear chromosome segregation
K9O37_02500	COG0739	heme binding
K9O37_02530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K9O37_02535	COG1183	phosphatidylcholine synthase activity
K9O37_02580	COG1960	acyl-CoA dehydrogenase activity
K9O37_02585	COG1309	transcriptional regulator
K9O37_02605	COG1960	acyl-CoA dehydrogenase activity
K9O37_02625	COG2969	positive regulation of protein catabolic process
K9O37_02635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K9O37_02650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K9O37_02655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K9O37_02675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K9O37_02685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9O37_02690	COG1408	metallophosphoesterase
K9O37_02700	COG2199	diguanylate cyclase activity
K9O37_02760	COG1607	acyl-coa hydrolase
K9O37_02790	COG2350	Protein conserved in bacteria
K9O37_02800	COG0613	PHP domain protein
K9O37_02805	COG3781	membrane
K9O37_02815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K9O37_02820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9O37_02830	COG1862	Preprotein translocase
K9O37_02860	COG2205	protein histidine kinase activity
K9O37_02865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K9O37_02880	COG0726	polysaccharide deacetylase
K9O37_02885	COG0438	transferase activity, transferring glycosyl groups
K9O37_02895	COG0438	transferase activity, transferring glycosyl groups
K9O37_02900	COG0438	transferase activity, transferring glycosyl groups
K9O37_02905	COG1442	glycosyl transferase family 8
K9O37_02955	COG1960	acyl-CoA dehydrogenase activity
K9O37_02960	COG1960	acyl-CoA dehydrogenase activity
K9O37_02970	COG2205	protein histidine kinase activity
K9O37_02975	COG0745	RESPONSE REGULATOR receiver
K9O37_02980	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K9O37_03000	COG2096	Adenosyltransferase
K9O37_03050	COG0285	dihydrofolate synthase activity
K9O37_03070	COG0450	alkyl hydroperoxide reductase
K9O37_03085	COG0477	Major facilitator Superfamily
K9O37_03090	COG1272	protein, Hemolysin III
K9O37_03100	COG2153	protein acetylation
K9O37_03120	COG0183	Belongs to the thiolase family
K9O37_03125	COG2207	Transcriptional regulator
K9O37_03145	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9O37_03165	COG0183	Belongs to the thiolase family
K9O37_03175	COG2885	chlorophyll binding
K9O37_03175	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9O37_03190	COG0833	amino acid
K9O37_03200	COG2233	PERMEase
K9O37_03205	COG1217	gtp-binding protein TYPA
K9O37_03230	COG2094	Belongs to the DNA glycosylase MPG family
K9O37_03235	COG4772	TonB-dependent receptor
K9O37_03240	COG1902	pentaerythritol trinitrate reductase activity
K9O37_03255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9O37_03260	COG0354	folic acid binding
K9O37_03275	COG2824	Alkylphosphonate utilization operon protein PhnA
K9O37_03280	COG3422	double-strand break repair
K9O37_03320	COG0840	transmembrane signaling receptor activity
K9O37_03340	COG5510	response to toxic substance
K9O37_03350	COG2832	Protein of unknown function (DUF454)
K9O37_03355	COG1376	ErfK ybiS ycfS ynhG family protein
K9O37_03405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K9O37_03415	COG1289	transmembrane transporter activity
K9O37_03420	COG2814	Major facilitator Superfamily
K9O37_03440	COG1115	amino acid carrier protein
K9O37_03445	COG1752	Esterase of the alpha-beta hydrolase superfamily
K9O37_03450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9O37_03455	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
K9O37_03460	COG3590	peptidase
K9O37_03485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K9O37_03495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K9O37_03500	COG1077	Cell shape determining protein MreB Mrl
K9O37_03505	COG1792	Involved in formation and maintenance of cell shape
K9O37_03510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
K9O37_03515	COG0424	maF-like protein
K9O37_03520	COG1530	ribonuclease E activity
K9O37_03530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9O37_03540	COG0560	Phosphoserine phosphatase
K9O37_03550	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9O37_03575	COG2207	Transcriptional regulator
K9O37_03595	COG1113	amino acid transport
K9O37_03600	COG2828	Protein conserved in bacteria
K9O37_03605	COG0142	geranyltranstransferase activity
K9O37_03610	COG2315	Protein conserved in bacteria
K9O37_03625	COG1752	Esterase of the alpha-beta hydrolase superfamily
K9O37_03645	COG2194	sulfuric ester hydrolase activity
K9O37_03650	COG0745	RESPONSE REGULATOR receiver
K9O37_03655	COG0642	Histidine kinase
K9O37_03665	COG0004	ammonium transporteR
K9O37_03670	COG0583	DNA-binding transcription factor activity
K9O37_03690	COG0525	valine-tRNA ligase activity
K9O37_03700	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_03710	COG0393	Putative heavy-metal-binding
K9O37_03715	COG0393	Putative heavy-metal-binding
K9O37_03720	COG1538	Outer membrane efflux protein
K9O37_03730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9O37_03735	COG0671	phosphoesterase, PA-phosphatase related
K9O37_03765	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K9O37_03780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K9O37_03780	COG1648	precorrin-2 dehydrogenase activity
K9O37_03785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K9O37_03790	COG1733	regulation of RNA biosynthetic process
K9O37_03800	COG0531	amino acid
K9O37_03815	COG0321	lipoyl(octanoyl) transferase activity
K9O37_03820	COG2921	Belongs to the UPF0250 family
K9O37_03860	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
K9O37_03865	COG1053	succinate dehydrogenase
K9O37_03870	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K9O37_03895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9O37_03915	COG2354	Protein conserved in bacteria
K9O37_03920	COG2321	neutral zinc metallopeptidase
K9O37_03940	COG3328	transposase activity
K9O37_03990	COG0589	response to stress
K9O37_04010	COG0505	Belongs to the CarA family
K9O37_04035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K9O37_04040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K9O37_04090	COG0477	Major facilitator Superfamily
K9O37_04095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K9O37_04115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K9O37_04140	COG3293	Transposase
K9O37_04150	COG0584	glycerophosphoryl diester phosphodiesterase
K9O37_04170	COG0741	lytic transglycosylase activity
K9O37_04190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9O37_04210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9O37_04215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K9O37_04245	COG3328	transposase activity
K9O37_04275	COG0778	Nitroreductase
K9O37_04290	COG1929	Belongs to the glycerate kinase type-1 family
K9O37_04295	COG0243	molybdopterin cofactor binding
K9O37_04300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K9O37_04305	COG3339	Conserved Protein
K9O37_04330	COG1113	amino acid transport
K9O37_04340	COG0019	diaminopimelate decarboxylase activity
K9O37_04350	COG1280	lysine exporter protein (LysE YggA)
K9O37_04355	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K9O37_04385	COG0463	Glycosyl transferase, family 2
K9O37_04405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9O37_04435	COG4591	ABC-type transport system involved in lipoprotein release permease component
K9O37_04440	COG1136	(ABC) transporter
K9O37_04445	COG0658	competence protein
K9O37_04445	COG2333	competence protein COMEC
K9O37_04455	COG0616	signal peptide processing
K9O37_04455	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K9O37_04460	COG0596	Alpha beta hydrolase
K9O37_04465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K9O37_04475	COG0628	permease
K9O37_04510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9O37_04530	COG0823	Involved in the tonB-independent uptake of proteins
K9O37_04550	COG0824	Thioesterase
K9O37_04555	COG1473	amidohydrolase
K9O37_04575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K9O37_04575	COG0047	phosphoribosylformylglycinamidine synthase activity
K9O37_04580	COG2814	Major facilitator Superfamily
K9O37_04590	COG1024	Enoyl-CoA hydratase
K9O37_04595	COG1056	cytidyltransferase-related domain
K9O37_04595	COG1051	belongs to the nudix hydrolase family
K9O37_04605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K9O37_04620	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K9O37_04635	COG4625	pathogenesis
K9O37_04640	COG0583	DNA-binding transcription factor activity
K9O37_04645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
K9O37_04650	COG4208	sulfate ABC transporter
K9O37_04655	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
K9O37_04665	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K9O37_04670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9O37_04675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K9O37_04695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9O37_04710	COG0681	Belongs to the peptidase S26 family
K9O37_04725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K9O37_04735	COG1381	Involved in DNA repair and RecF pathway recombination
K9O37_04740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K9O37_04750	COG4221	oxidoreductase activity
K9O37_04780	COG0436	Aminotransferase
K9O37_04800	COG0556	nucleotide-excision repair
K9O37_04855	COG2070	2-Nitropropane dioxygenase
K9O37_04885	COG0415	Belongs to the DNA photolyase family
K9O37_04895	COG1252	NADH dehydrogenase
K9O37_04900	COG1686	Belongs to the peptidase S11 family
K9O37_04915	COG1187	pseudouridine synthase activity
K9O37_04940	COG0477	Major facilitator Superfamily
K9O37_04945	COG0583	DNA-binding transcription factor activity
K9O37_04950	COG1823	symporter activity
K9O37_04960	COG0612	Peptidase, M16
K9O37_04990	COG1203	CRISPR-associated helicase, Cas3
K9O37_05015	COG0352	thiamine-phosphate diphosphorylase activity
K9O37_05050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9O37_05065	COG1309	transcriptional regulator
K9O37_05075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K9O37_05080	COG0076	glutamate decarboxylase activity
K9O37_05090	COG1522	sequence-specific DNA binding
K9O37_05095	COG3961	Belongs to the TPP enzyme family
K9O37_05100	COG1113	amino acid transport
K9O37_05105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K9O37_05110	COG0573	inorganic phosphate transmembrane transporter activity
K9O37_05120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K9O37_05125	COG0616	signal peptide processing
K9O37_05160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K9O37_05165	COG1686	Belongs to the peptidase S11 family
K9O37_05190	COG0583	DNA-binding transcription factor activity
K9O37_05195	COG1067	ATP-dependent peptidase activity
K9O37_05200	COG2211	Major facilitator Superfamily
K9O37_05220	COG4943	cyclic-guanylate-specific phosphodiesterase activity
K9O37_05240	COG1966	Carbon starvation protein
K9O37_05245	COG2879	small protein
K9O37_05255	COG0582	viral genome integration into host DNA
K9O37_05275	COG3328	transposase activity
K9O37_05305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9O37_05310	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9O37_05315	COG4605	iron ion homeostasis
K9O37_05320	COG4604	ABC transporter, ATP-binding protein
K9O37_05325	COG4607	ABC-type enterochelin transport system periplasmic component
K9O37_05330	COG4774	siderophore transport
K9O37_05340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9O37_05345	COG1021	2,3-dihydroxybenzoate-AMP ligase
K9O37_05350	COG3433	isochorismatase activity
K9O37_05350	COG1535	isochorismatase
K9O37_05360	COG1132	(ABC) transporter
K9O37_05365	COG1132	(ABC) transporter
K9O37_05370	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
K9O37_05375	COG2977	Belongs to the P-Pant transferase superfamily
K9O37_05380	COG1169	isochorismate synthase
K9O37_05395	COG3739	integral membrane protein
K9O37_05415	COG0302	gtp cyclohydrolase
K9O37_05425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9O37_05435	COG2840	Smr protein MutS2
K9O37_05455	COG0308	aminopeptidase N
K9O37_05460	COG0512	Glutamine amidotransferase of anthranilate synthase
K9O37_05475	COG0174	glutamine synthetase
K9O37_05485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K9O37_05520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K9O37_05525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K9O37_05530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9O37_05550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K9O37_05555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K9O37_05560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K9O37_05575	COG1960	acyl-CoA dehydrogenase activity
K9O37_05580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K9O37_05585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9O37_05595	COG2223	nitrite transmembrane transporter activity
K9O37_05605	COG0024	Methionine aminopeptidase
K9O37_05610	COG0052	Belongs to the universal ribosomal protein uS2 family
K9O37_05625	COG2207	Transcriptional regulator
K9O37_05635	COG3328	transposase activity
K9O37_05660	COG2951	lytic endotransglycosylase activity
K9O37_05665	COG0772	Belongs to the SEDS family
K9O37_05680	COG0842	Transport permease protein
K9O37_05685	COG1131	(ABC) transporter
K9O37_05690	COG0582	viral genome integration into host DNA
K9O37_05760	COG3620	sequence-specific DNA binding
K9O37_05930	COG3646	Phage regulatory protein
K9O37_06105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9O37_06120	COG4215	(ABC) transporter
K9O37_06125	COG4160	amino acid transport
K9O37_06130	COG4598	ABC transporter
K9O37_06160	COG3566	protein conserved in bacteria
K9O37_06265	COG0582	viral genome integration into host DNA
K9O37_06275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K9O37_06285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K9O37_06300	COG0667	Aldo Keto reductase
K9O37_06315	COG1765	OsmC-like protein
K9O37_06330	COG0542	response to heat
K9O37_06365	COG2885	chlorophyll binding
K9O37_06375	COG0625	glutathione transferase activity
K9O37_06380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K9O37_06400	COG3634	alkyl hydroperoxide reductase activity
K9O37_06410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K9O37_06420	COG0450	alkyl hydroperoxide reductase
K9O37_06425	COG1643	Atp-dependent helicase
K9O37_06440	COG2814	Major facilitator Superfamily
K9O37_06445	COG3135	benzoate transporter
K9O37_06450	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_06455	COG0543	2 iron, 2 sulfur cluster binding
K9O37_06455	COG0633	Ferredoxin
K9O37_06460	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
K9O37_06465	COG4638	Rieske (2fe-2S)
K9O37_06485	COG2871	sodium ion transport
K9O37_06565	COG1570	exodeoxyribonuclease VII activity
K9O37_06595	COG1280	lysine exporter protein (LysE YggA)
K9O37_06600	COG1278	Cold shock
K9O37_06635	COG2814	Major facilitator Superfamily
K9O37_06685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K9O37_06685	COG0517	IMP dehydrogenase activity
K9O37_06690	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
K9O37_06700	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K9O37_06705	COG1137	ATPase activity
K9O37_06710	COG1538	Outer membrane efflux protein
K9O37_06740	COG4122	O-methyltransferase activity
K9O37_06750	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K9O37_06765	COG1522	sequence-specific DNA binding
K9O37_06770	COG5006	permease, DMT superfamily
K9O37_06780	COG1560	Kdo2-lipid A biosynthetic process
K9O37_06785	COG0598	Magnesium transport protein CorA
K9O37_06815	COG2814	Major facilitator Superfamily
K9O37_06835	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9O37_06855	COG0583	DNA-binding transcription factor activity
K9O37_06860	COG1914	H( )-stimulated, divalent metal cation uptake system
K9O37_06880	COG4770	biotin carboxylase activity
K9O37_06885	COG0038	chloride channel
K9O37_06895	COG1309	transcriptional regulator
K9O37_06905	COG1063	alcohol dehydrogenase
K9O37_06920	COG0439	Biotin carboxylase
K9O37_06925	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9O37_06930	COG1733	regulation of RNA biosynthetic process
K9O37_06940	COG0864	Transcriptional regulator
K9O37_06950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9O37_06955	COG1116	anion transmembrane transporter activity
K9O37_06965	COG3328	transposase activity
K9O37_06985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K9O37_06995	COG0789	Transcriptional regulator
K9O37_07005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9O37_07025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9O37_07040	COG0531	amino acid
K9O37_07045	COG1760	l-serine dehydratase
K9O37_07050	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_07050	COG2030	dehydratase
K9O37_07055	COG3396	Phenylacetate-CoA oxygenase
K9O37_07060	COG3460	Phenylacetate-CoA oxygenase
K9O37_07065	COG3396	Phenylacetate-CoA oxygenase
K9O37_07070	COG2151	metal-sulfur cluster biosynthetic enzyme
K9O37_07075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9O37_07080	COG1024	Enoyl-CoA hydratase
K9O37_07085	COG1024	Enoyl-CoA hydratase
K9O37_07090	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9O37_07095	COG0183	Belongs to the thiolase family
K9O37_07100	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K9O37_07105	COG3327	negative regulation of DNA-templated transcription, initiation
K9O37_07115	COG2050	protein possibly involved in aromatic compounds catabolism
K9O37_07125	COG0556	nucleotide-excision repair
K9O37_07140	COG0583	DNA-binding transcription factor activity
K9O37_07150	COG1414	Transcriptional regulator
K9O37_07155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9O37_07165	COG1840	ABC-type Fe3 transport system, periplasmic component
K9O37_07170	COG3842	ATPase activity
K9O37_07185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K9O37_07190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9O37_07195	COG2814	Major facilitator Superfamily
K9O37_07200	COG1960	acyl-CoA dehydrogenase activity
K9O37_07205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9O37_07215	COG1024	Enoyl-CoA hydratase
K9O37_07225	COG2814	Major facilitator Superfamily
K9O37_07235	COG0183	Belongs to the thiolase family
K9O37_07240	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9O37_07245	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_07250	COG1024	Enoyl-CoA hydratase
K9O37_07255	COG1960	acyl-CoA dehydrogenase activity
K9O37_07260	COG2814	Major facilitator Superfamily
K9O37_07265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9O37_07270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K9O37_07280	COG2814	Major facilitator Superfamily
K9O37_07290	COG1960	acyl-CoA dehydrogenase activity
K9O37_07305	COG0583	DNA-binding transcription factor activity
K9O37_07315	COG4770	biotin carboxylase activity
K9O37_07320	COG1024	Enoyl-CoA hydratase
K9O37_07325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K9O37_07330	COG1960	acyl-CoA dehydrogenase activity
K9O37_07335	COG1309	transcriptional regulator
K9O37_07340	COG0318	PFAM AMP-dependent synthetase and ligase
K9O37_07360	COG0583	DNA-binding transcription factor activity
K9O37_07420	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_07440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K9O37_07460	COG2205	protein histidine kinase activity
K9O37_07460	COG0784	Response regulator, receiver
K9O37_07475	COG1045	serine acetyltransferase
K9O37_07490	COG0583	DNA-binding transcription factor activity
K9O37_07495	COG0625	glutathione transferase activity
K9O37_07500	COG0625	glutathione transferase activity
K9O37_07505	COG0583	DNA-binding transcription factor activity
K9O37_07515	COG1346	cytolysis
K9O37_07540	COG0300	oxidoreductase activity
K9O37_07550	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
K9O37_07555	COG3052	prosthetic group binding
K9O37_07575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K9O37_07595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9O37_07605	COG1294	oxidase, subunit
K9O37_07610	COG1271	oxidase subunit
K9O37_07630	COG0477	Major facilitator Superfamily
K9O37_07640	COG4521	taurine ABC transporter
K9O37_07645	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
K9O37_07650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9O37_07655	COG2175	clavaminate synthase activity
K9O37_07665	COG1953	Uracil, thiamine, allantoin
K9O37_07675	COG0583	DNA-binding transcription factor activity
K9O37_07685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K9O37_07700	COG0640	Transcriptional regulator
K9O37_07705	COG0798	PFAM Bile acid sodium symporter
K9O37_07710	COG0583	DNA-binding transcription factor activity
K9O37_07725	COG3634	alkyl hydroperoxide reductase activity
K9O37_07765	COG0436	Aminotransferase
K9O37_07775	COG0386	Belongs to the glutathione peroxidase family
K9O37_07815	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K9O37_07840	COG0012	GTP binding
K9O37_07845	COG2011	ABC-type metal ion transport system permease component
K9O37_07850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K9O37_07860	COG1464	Belongs to the NlpA lipoprotein family
K9O37_07890	COG0765	amino acid transport
K9O37_07895	COG0765	amino acid transport
K9O37_07900	COG1126	abc transporter atp-binding protein
K9O37_07910	COG1522	sequence-specific DNA binding
K9O37_07925	COG1309	transcriptional regulator
K9O37_07950	COG0583	DNA-binding transcription factor activity
K9O37_07960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K9O37_07970	COG0697	spore germination
K9O37_08010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K9O37_08010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K9O37_08055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K9O37_08065	COG2353	YceI-like domain
K9O37_08080	COG3698	Phosphodiester glycosidase
K9O37_08095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K9O37_08100	COG0506	proline dehydrogenase activity
K9O37_08100	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K9O37_08100	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K9O37_08110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9O37_08115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K9O37_08135	COG1132	(ABC) transporter
K9O37_08140	COG3122	Protein conserved in bacteria
K9O37_08145	COG3619	membrane
K9O37_08155	COG0640	Transcriptional regulator
K9O37_08165	COG2850	peptidyl-arginine hydroxylation
K9O37_08170	COG0424	maF-like protein
K9O37_08190	COG0191	fructose-bisphosphate aldolase activity
K9O37_08195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9O37_08210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K9O37_08220	COG1192	Involved in chromosome partitioning
K9O37_08225	COG1475	DNA binding
K9O37_08230	COG0811	peptide transport
K9O37_08240	COG1132	(ABC) transporter
K9O37_08245	COG1663	tetraacyldisaccharide 4'-kinase activity
K9O37_08265	COG0084	hydrolase, TatD family'
K9O37_08330	COG0776	regulation of translation
K9O37_08360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K9O37_08365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K9O37_08415	COG0339	signal peptide processing
K9O37_08425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9O37_08460	COG0702	epimerase
K9O37_08465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K9O37_08485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K9O37_08515	COG0316	Belongs to the HesB IscA family
K9O37_08520	COG0822	iron-sulfur transferase activity
K9O37_08545	COG0776	regulation of translation
K9O37_08550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9O37_08570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9O37_08575	COG1960	acyl-CoA dehydrogenase activity
K9O37_08580	COG1960	acyl-CoA dehydrogenase activity
K9O37_08595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K9O37_08615	COG4264	IucA IucC family
K9O37_08620	COG4264	IucA IucC family
K9O37_08630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K9O37_08660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9O37_08675	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K9O37_08680	COG0406	alpha-ribazole phosphatase activity
K9O37_08695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K9O37_08700	COG0730	response to heat
K9O37_08735	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9O37_08750	COG1131	(ABC) transporter
K9O37_08755	COG0842	Transport permease protein
K9O37_08760	COG0842	Transport permease protein
K9O37_08815	COG2226	methyltransferase
K9O37_08840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K9O37_08875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K9O37_08885	COG0133	tryptophan synthase activity
K9O37_08900	COG3706	GGDEF domain
K9O37_08915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K9O37_08920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K9O37_08925	COG0022	dehydrogenase e1 component
K9O37_08930	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9O37_08935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9O37_08960	COG1063	alcohol dehydrogenase
K9O37_08965	COG3781	membrane
K9O37_08975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9O37_08975	COG3453	Protein conserved in bacteria
K9O37_08985	COG0730	response to heat
K9O37_09000	COG3708	Transcriptional regulator
K9O37_09000	COG2207	Transcriptional regulator
K9O37_09005	COG1733	regulation of RNA biosynthetic process
K9O37_09010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K9O37_09020	COG2188	Transcriptional regulator
K9O37_09035	COG4521	taurine ABC transporter
K9O37_09060	COG1027	Aspartate ammonia-lyase
K9O37_09075	COG0583	DNA-binding transcription factor activity
K9O37_09080	COG0583	DNA-binding transcription factor activity
K9O37_09085	COG0183	Belongs to the thiolase family
K9O37_09090	COG2031	fatty acid transporter
K9O37_09105	COG0583	DNA-binding transcription factor activity
K9O37_09125	COG1309	transcriptional regulator
K9O37_09155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9O37_09155	COG0543	2 iron, 2 sulfur cluster binding
K9O37_09160	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
K9O37_09165	COG4638	Rieske (2fe-2S)
K9O37_09175	COG0725	ABC transporter, periplasmic molybdate-binding protein
K9O37_09180	COG4149	molybdate abc transporter
K9O37_09185	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K9O37_09190	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_09195	COG1535	isochorismatase
K9O37_09195	COG3433	isochorismatase activity
K9O37_09255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9O37_09270	COG0753	catalase activity
K9O37_09280	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K9O37_09385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9O37_09460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K9O37_09480	COG1120	ATPase activity
K9O37_09485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9O37_09500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9O37_09505	COG0583	DNA-binding transcription factor activity
K9O37_09530	COG2186	Transcriptional regulator
K9O37_09540	COG0583	DNA-binding transcription factor activity
K9O37_09545	COG4948	Mandelate Racemase Muconate Lactonizing
K9O37_09550	COG4829	muconolactone delta-isomerase
K9O37_09560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9O37_09565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K9O37_09570	COG0183	Belongs to the thiolase family
K9O37_09575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9O37_09580	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_09590	COG3733	amine oxidase
K9O37_09600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9O37_09610	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_09620	COG4638	Rieske (2fe-2S)
K9O37_09640	COG0154	amidase activity
K9O37_09650	COG2814	Major facilitator Superfamily
K9O37_09675	COG1960	acyl-CoA dehydrogenase activity
K9O37_09680	COG0583	DNA-binding transcription factor activity
K9O37_09685	COG1414	Transcriptional regulator
K9O37_09700	COG2391	methyltransferase activity
K9O37_09710	COG4993	Dehydrogenase
K9O37_09715	COG3659	wide pore channel activity
K9O37_09720	COG3420	alginic acid biosynthetic process
K9O37_09725	COG0710	3-dehydroquinate dehydratase activity
K9O37_09730	COG3485	protocatechuate 3,4-dioxygenase
K9O37_09735	COG3485	protocatechuate 3,4-dioxygenase
K9O37_09740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9O37_09745	COG2271	Major facilitator Superfamily
K9O37_09750	COG0596	Alpha beta hydrolase
K9O37_09755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K9O37_09760	COG0183	Belongs to the thiolase family
K9O37_09765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K9O37_09770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9O37_09780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
K9O37_09785	COG2323	membrane
K9O37_09830	COG1902	pentaerythritol trinitrate reductase activity
K9O37_09830	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9O37_09855	COG0542	response to heat
K9O37_09860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K9O37_09890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9O37_09895	COG0569	domain protein
K9O37_09900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K9O37_09915	COG4774	siderophore transport
K9O37_09920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9O37_09930	COG1585	Membrane protein implicated in regulation of membrane protease activity
K9O37_09945	COG1294	oxidase, subunit
K9O37_09950	COG4890	Cyd operon protein YbgT
K9O37_09960	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K9O37_09970	COG0552	protein localization to endoplasmic reticulum
K9O37_09995	COG0516	GMP reductase activity
K9O37_09995	COG0517	IMP dehydrogenase activity
K9O37_10000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9O37_10005	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K9O37_10015	COG0583	DNA-binding transcription factor activity
K9O37_10020	COG0024	Methionine aminopeptidase
K9O37_10050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K9O37_10050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9O37_10055	COG1105	Belongs to the carbohydrate kinase PfkB family
K9O37_10060	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
K9O37_10060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9O37_10060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9O37_10075	COG3300	MHYT domain
K9O37_10075	COG5001	Diguanylate cyclase
K9O37_10090	COG2135	peptidase activity
K9O37_10095	COG0659	secondary active sulfate transmembrane transporter activity
K9O37_10120	COG3328	transposase activity
K9O37_10135	COG1522	sequence-specific DNA binding
K9O37_10165	COG1011	Hydrolase
K9O37_10170	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K9O37_10180	COG2137	regulation of response to DNA damage stimulus
K9O37_10195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9O37_10230	COG0575	Belongs to the CDS family
K9O37_10235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K9O37_10260	COG3852	Histidine kinase
K9O37_10265	COG2204	response regulator
K9O37_10320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K9O37_10325	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
K9O37_10345	COG0697	spore germination
K9O37_10350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9O37_10360	COG0303	'Molybdopterin
K9O37_10365	COG0521	Mo-molybdopterin cofactor biosynthetic process
K9O37_10365	COG0315	cyclic pyranopterin monophosphate synthase activity
K9O37_10380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K9O37_10385	COG0243	molybdopterin cofactor binding
K9O37_10395	COG0243	molybdopterin cofactor binding
K9O37_10400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9O37_10405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9O37_10405	COG2146	nitrite reductase [NAD(P)H] activity
K9O37_10415	COG0745	RESPONSE REGULATOR receiver
K9O37_10475	COG0511	ligase activity, forming carbon-carbon bonds
K9O37_10490	COG2814	Major facilitator Superfamily
K9O37_10610	COG1598	PFAM Uncharacterised protein family UPF0150
K9O37_10705	COG5410	chromosome segregation
K9O37_10875	COG0069	glutamate synthase activity
K9O37_10895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K9O37_10905	COG1454	alcohol dehydrogenase
K9O37_10910	COG0824	Thioesterase
K9O37_10920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K9O37_10935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K9O37_10940	COG2030	dehydratase
K9O37_10950	COG0183	Belongs to the thiolase family
K9O37_10965	COG0583	DNA-binding transcription factor activity
K9O37_10970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K9O37_10980	COG1522	sequence-specific DNA binding
K9O37_10985	COG3135	benzoate transporter
K9O37_11020	COG0589	response to stress
K9O37_11025	COG0488	(ABC) transporter
K9O37_11045	COG4773	Receptor
K9O37_11065	COG0668	transmembrane transport
K9O37_11115	COG0583	DNA-binding transcription factor activity
K9O37_11120	COG2814	Major facilitator Superfamily
K9O37_11125	COG2814	Major facilitator Superfamily
K9O37_11170	COG4569	acetaldehyde dehydrogenase (acetylating) activity
K9O37_11175	COG3971	2-oxopent-4-enoate hydratase activity
K9O37_11185	COG2271	Major facilitator Superfamily
K9O37_11250	COG1605	Chorismate mutase
K9O37_11270	COG0308	aminopeptidase N
K9O37_11300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9O37_11305	COG1454	alcohol dehydrogenase
K9O37_11325	COG0531	amino acid
K9O37_11330	COG4303	Ethanolamine ammonia lyase large subunit
K9O37_11335	COG4302	ethanolamine ammonia-lyase activity
K9O37_11340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K9O37_11340	COG0519	Catalyzes the synthesis of GMP from XMP
K9O37_11345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9O37_11370	COG0697	spore germination
K9O37_11375	COG1923	regulation of RNA biosynthetic process
K9O37_11385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K9O37_11390	COG0802	atpase or kinase
K9O37_11410	COG1187	pseudouridine synthase activity
K9O37_11430	COG0583	DNA-binding transcription factor activity
K9O37_11445	COG2814	Major facilitator Superfamily
K9O37_11450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9O37_11475	COG0729	surface antigen
K9O37_11495	COG0174	glutamine synthetase
K9O37_11500	COG0745	RESPONSE REGULATOR receiver
K9O37_11505	COG2205	protein histidine kinase activity
K9O37_11510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K9O37_11515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K9O37_11520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K9O37_11545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9O37_11550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9O37_11555	COG1960	acyl-CoA dehydrogenase activity
K9O37_11580	COG3328	transposase activity
K9O37_11590	COG0583	DNA-binding transcription factor activity
K9O37_11605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9O37_11615	COG3658	cytochrome
K9O37_11620	COG1215	transferase activity, transferring glycosyl groups
K9O37_11625	COG1649	PFAM Uncharacterised BCR, COG1649
K9O37_11625	COG0726	polysaccharide deacetylase
K9O37_11650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9O37_11655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K9O37_11665	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K9O37_11690	COG0305	Participates in initiation and elongation during chromosome replication
K9O37_11695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9O37_11705	COG1305	Transglutaminase-like
K9O37_11745	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
K9O37_11750	COG0138	bifunctional purine biosynthesis protein purh
K9O37_11755	COG0151	Belongs to the GarS family
K9O37_11760	COG1464	Belongs to the NlpA lipoprotein family
K9O37_11765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K9O37_11770	COG2011	ABC-type metal ion transport system permease component
K9O37_11775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9O37_11785	COG1301	dicarboxylic acid transport
K9O37_11820	COG1794	racemase activity, acting on amino acids and derivatives
K9O37_11825	COG3118	belongs to the thioredoxin family
K9O37_11825	COG0492	ferredoxin-NADP+ reductase activity
K9O37_11840	COG3008	intermembrane lipid transfer
K9O37_11840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K9O37_11845	COG2995	paraquat-inducible protein a
K9O37_11895	COG2186	Transcriptional regulator
K9O37_11905	COG0786	glutamate:sodium symporter activity
K9O37_11910	COG3243	poly(R)-hydroxyalkanoic acid synthase
K9O37_11940	COG3111	PFAM Bacterial OB fold (BOF) protein
K9O37_12080	COG2831	hemolysin activation secretion protein
K9O37_12105	COG0515	serine threonine protein kinase
K9O37_12105	COG2815	serine threonine protein kinase
K9O37_12135	COG1610	YqeY-like protein
K9O37_12140	COG4783	chaperone-mediated protein folding
K9O37_12165	COG1286	toxin biosynthetic process
K9O37_12210	COG3646	Phage regulatory protein
K9O37_12290	COG0778	Nitroreductase
K9O37_12300	COG0513	Belongs to the DEAD box helicase family
K9O37_12320	COG2363	Small membrane protein
K9O37_12350	COG4650	regulator
K9O37_12355	COG1234	tRNA 3'-trailer cleavage
K9O37_12360	COG1690	Belongs to the RtcB family
K9O37_12380	COG2195	Cleaves the N-terminal amino acid of tripeptides
K9O37_12390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K9O37_12400	COG2819	hydrolase of the alpha beta superfamily
K9O37_12405	COG1960	acyl-CoA dehydrogenase activity
K9O37_12410	COG1301	dicarboxylic acid transport
K9O37_12420	COG3139	Protein of unknown function (DUF1315)
K9O37_12425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K9O37_12430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K9O37_12440	COG0494	nUDIX hydrolase
K9O37_12450	COG0642	Histidine kinase
K9O37_12465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K9O37_12475	COG1720	tRNA m6t6A37 methyltransferase activity
K9O37_12490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9O37_12495	COG0826	peptidase U32
K9O37_12500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9O37_12525	COG3328	transposase activity
K9O37_12535	COG5410	chromosome segregation
K9O37_12580	COG3328	transposase activity
K9O37_12595	COG0527	aspartate kinase activity
K9O37_12605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K9O37_12615	COG3038	cytochrome b561
K9O37_12620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K9O37_12625	COG2252	PERMEase
K9O37_12635	COG2072	flavoprotein involved in K transport
K9O37_12650	COG1741	Belongs to the pirin family
K9O37_12655	COG1309	transcriptional regulator
K9O37_12665	COG0300	oxidoreductase activity
K9O37_12670	COG2072	flavoprotein involved in K transport
K9O37_12675	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K9O37_12680	COG0583	DNA-binding transcription factor activity
K9O37_12695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K9O37_12740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9O37_12755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9O37_12770	COG2814	Major facilitator Superfamily
K9O37_12775	COG1024	Enoyl-CoA hydratase
K9O37_12780	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_12790	COG1960	acyl-CoA dehydrogenase activity
K9O37_12815	COG2186	Transcriptional regulator
K9O37_12820	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_12830	COG4948	Mandelate Racemase Muconate Lactonizing
K9O37_12835	COG2271	Major facilitator Superfamily
K9O37_12840	COG2721	sulfolactate sulfo-lyase activity
K9O37_12845	COG0697	spore germination
K9O37_12860	COG1113	amino acid transport
K9O37_12880	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_12900	COG0531	amino acid
K9O37_12910	COG1113	amino acid transport
K9O37_12930	COG1454	alcohol dehydrogenase
K9O37_12935	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_12950	COG2814	Major facilitator Superfamily
K9O37_12955	COG0583	DNA-binding transcription factor activity
K9O37_12965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9O37_13000	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K9O37_13000	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K9O37_13025	COG0514	ATP-dependent DNA helicase (RecQ)
K9O37_13060	COG1309	transcriptional regulator
K9O37_13120	COG0582	viral genome integration into host DNA
K9O37_13130	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9O37_13130	COG1902	pentaerythritol trinitrate reductase activity
K9O37_13145	COG2203	Gaf domain
K9O37_13145	COG3706	GGDEF domain
K9O37_13145	COG5001	Diguanylate cyclase
K9O37_13145	COG4251	negative regulation of phosphorylation
K9O37_13155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K9O37_13175	COG4172	Belongs to the ABC transporter superfamily
K9O37_13180	COG4239	(ABC) transporter, permease
K9O37_13185	COG4174	ABC transporter (Permease)
K9O37_13195	COG0741	lytic transglycosylase activity
K9O37_13195	COG1388	LysM domain
K9O37_13195	COG0741	lytic transglycosylase activity
K9O37_13195	COG1388	LysM domain
K9O37_13200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K9O37_13240	COG0583	DNA-binding transcription factor activity
K9O37_13245	COG1279	arginine transmembrane transporter activity
K9O37_13265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9O37_13270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9O37_13275	COG0006	proline dipeptidase activity
K9O37_13315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K9O37_13330	COG3384	dioxygenase
K9O37_13340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K9O37_13345	COG2878	Part of a membrane complex involved in electron transport
K9O37_13350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K9O37_13375	COG0768	penicillin binding
K9O37_13380	COG0742	ribosomal rna small subunit methyltransferase
K9O37_13395	COG0830	nickel cation binding
K9O37_13440	COG1253	flavin adenine dinucleotide binding
K9O37_13445	COG2851	Citrate transporter
K9O37_13495	COG1773	rubredoxin
K9O37_13500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9O37_13510	COG0583	DNA-binding transcription factor activity
K9O37_13545	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
K9O37_13550	COG4181	ATPase activity
K9O37_13600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9O37_13620	COG0306	phosphate transporter
K9O37_13635	COG3959	Transketolase, thiamine diphosphate binding domain
K9O37_13640	COG2271	Major facilitator Superfamily
K9O37_13645	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_13650	COG0583	DNA-binding transcription factor activity
K9O37_13665	COG2223	nitrite transmembrane transporter activity
K9O37_13670	COG2207	Transcriptional regulator
K9O37_13675	COG2066	Belongs to the glutaminase family
K9O37_13680	COG0242	peptide deformylase activity
K9O37_13685	COG0477	Major facilitator Superfamily
K9O37_13695	COG0028	Belongs to the TPP enzyme family
K9O37_13710	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_13715	COG2267	carboxylic ester hydrolase activity
K9O37_13725	COG2271	Major facilitator Superfamily
K9O37_13740	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_13760	COG1414	Transcriptional regulator
K9O37_13775	COG1024	Enoyl-CoA hydratase
K9O37_13785	COG1215	transferase activity, transferring glycosyl groups
K9O37_13790	COG0726	polysaccharide deacetylase
K9O37_13790	COG1649	PFAM Uncharacterised BCR, COG1649
K9O37_13800	COG4681	YaeQ
K9O37_13810	COG0523	cobalamin synthesis protein
K9O37_13820	COG1607	acyl-coa hydrolase
K9O37_13830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9O37_13835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9O37_13840	COG1309	transcriptional regulator
K9O37_13865	COG2040	homocysteine
K9O37_13870	COG0531	amino acid
K9O37_13925	COG1595	DNA-templated transcription, initiation
K9O37_13935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9O37_13940	COG0477	Major facilitator Superfamily
K9O37_13950	COG2801	Transposase and inactivated derivatives
K9O37_13955	COG3328	transposase activity
K9O37_14005	COG3328	transposase activity
K9O37_14020	COG0582	viral genome integration into host DNA
K9O37_14030	COG0405	Gamma-glutamyltransferase
K9O37_14035	COG2814	Major facilitator Superfamily
K9O37_14045	COG2050	protein possibly involved in aromatic compounds catabolism
K9O37_14060	COG1090	epimerase
K9O37_14080	COG0420	3'-5' exonuclease activity
K9O37_14105	COG0735	belongs to the Fur family
K9O37_14110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9O37_14130	COG0121	glutamine amidotransferase
K9O37_14145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9O37_14155	COG0210	DNA helicase
K9O37_14160	COG2885	chlorophyll binding
K9O37_14165	COG0204	Acyl-transferase
K9O37_14180	COG2894	cell division
K9O37_14195	COG1280	lysine exporter protein (LysE YggA)
K9O37_14200	COG1674	ftsk spoiiie
K9O37_14200	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K9O37_14205	COG0492	ferredoxin-NADP+ reductase activity
K9O37_14210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K9O37_14220	COG0456	acetyltransferase
K9O37_14265	COG1981	membrane
K9O37_14275	COG3328	transposase activity
K9O37_14285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K9O37_14285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9O37_14305	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_14315	COG0657	acetylesterase activity
K9O37_14325	COG0473	3-isopropylmalate dehydrogenase activity
K9O37_14330	COG0583	DNA-binding transcription factor activity
K9O37_14350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9O37_14375	COG0564	pseudouridine synthase activity
K9O37_14385	COG0358	DNA primase activity
K9O37_14400	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
K9O37_14430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K9O37_14460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9O37_14470	COG0351	phosphomethylpyrimidine kinase
K9O37_14470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K9O37_14470	COG0352	thiamine-phosphate diphosphorylase activity
K9O37_14475	COG1652	LysM domain
K9O37_14500	COG1399	metal-binding, possibly nucleic acid-binding protein
K9O37_14505	COG3101	peptidyl-lysine hydroxylation
K9O37_14510	COG0009	L-threonylcarbamoyladenylate synthase
K9O37_14515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K9O37_14520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K9O37_14535	COG4106	trans-aconitate 2-methyltransferase activity
K9O37_14550	COG2226	methyltransferase
K9O37_14550	COG0596	Alpha beta hydrolase
K9O37_14550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9O37_14555	COG1877	trehalose-phosphatase activity
K9O37_14560	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
K9O37_14565	COG2223	nitrite transmembrane transporter activity
K9O37_14585	COG1196	nuclear chromosome segregation
K9O37_14595	COG0730	response to heat
K9O37_14610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K9O37_14620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9O37_14685	COG0489	protein tyrosine kinase activity
K9O37_14695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9O37_14695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9O37_14725	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K9O37_14730	COG2081	HI0933 family
K9O37_14740	COG0668	transmembrane transport
K9O37_14760	COG0583	DNA-binding transcription factor activity
K9O37_14780	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9O37_14785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K9O37_14815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K9O37_14855	COG0745	RESPONSE REGULATOR receiver
K9O37_14875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K9O37_14915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9O37_14950	COG0583	DNA-binding transcription factor activity
K9O37_14975	COG0583	DNA-binding transcription factor activity
K9O37_14980	COG1053	succinate dehydrogenase
K9O37_14990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9O37_14995	COG2814	Major facilitator Superfamily
K9O37_15000	COG1960	acyl-CoA dehydrogenase activity
K9O37_15005	COG0583	DNA-binding transcription factor activity
K9O37_15010	COG1063	alcohol dehydrogenase
K9O37_15040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K9O37_15045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K9O37_15050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K9O37_15070	COG2132	Multicopper oxidase
K9O37_15080	COG0561	phosphatase activity
K9O37_15085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K9O37_15095	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
K9O37_15110	COG1214	PFAM Peptidase M22, glycoprotease
K9O37_15135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K9O37_15145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9O37_15150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K9O37_15155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K9O37_15215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9O37_15225	COG1846	Transcriptional regulator
K9O37_15230	COG1764	response to oxidative stress
K9O37_15270	COG0037	tRNA processing
K9O37_15280	COG0248	Ppx GppA phosphatase
K9O37_15310	COG0072	phenylalanine-tRNA ligase activity
K9O37_15350	COG1238	metal cluster binding
K9O37_15355	COG0625	glutathione transferase activity
K9O37_15370	COG0318	PFAM AMP-dependent synthetase and ligase
K9O37_15375	COG3028	Belongs to the UPF0307 family
K9O37_15380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9O37_15400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K9O37_15405	COG0617	tRNA 3'-terminal CCA addition
K9O37_15410	COG1555	photosystem II stabilization
K9O37_15415	COG3956	TIGRFAM MazG family protein
K9O37_15425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9O37_15445	COG5002	protein histidine kinase activity
K9O37_15445	COG2205	protein histidine kinase activity
K9O37_15445	COG0784	Response regulator, receiver
K9O37_15450	COG1024	Enoyl-CoA hydratase
K9O37_15455	COG2084	Dehydrogenase
K9O37_15460	COG3622	Belongs to the hyi family
K9O37_15490	COG0697	spore germination
K9O37_15500	COG2814	Major facilitator Superfamily
K9O37_15575	COG2132	Multicopper oxidase
K9O37_15590	COG2205	protein histidine kinase activity
K9O37_15650	COG3328	transposase activity
K9O37_15660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9O37_15690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K9O37_15705	COG0084	hydrolase, TatD family'
K9O37_15720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K9O37_15745	COG2130	NADP-dependent
K9O37_15750	COG1309	transcriptional regulator
K9O37_15770	COG1979	alcohol dehydrogenase
K9O37_15780	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
K9O37_15795	COG0604	alcohol dehydrogenase
K9O37_15795	COG3321	synthase
K9O37_15800	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K9O37_15805	COG0583	DNA-binding transcription factor activity
K9O37_15810	COG4221	oxidoreductase activity
K9O37_16005	COG0440	acetolactate synthase activity
K9O37_16010	COG0028	Belongs to the TPP enzyme family
K9O37_16040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9O37_16045	COG1136	(ABC) transporter
K9O37_16045	COG0577	efflux transmembrane transporter activity
K9O37_16050	COG1538	Outer membrane efflux protein
K9O37_16070	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K9O37_16075	COG1162	GTPase activity
K9O37_16085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K9O37_16125	COG1426	Protein conserved in bacteria
K9O37_16160	COG0793	Belongs to the peptidase S41A family
K9O37_16175	COG2267	carboxylic ester hydrolase activity
K9O37_16185	COG1012	belongs to the aldehyde dehydrogenase family
K9O37_16190	COG3265	gluconokinase activity
K9O37_16200	COG0800	Aldolase
K9O37_16210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K9O37_16215	COG0857	belongs to the CobB CobQ family
K9O37_16215	COG0280	phosphate acetyltransferase
K9O37_16220	COG3328	transposase activity
K9O37_16225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
K9O37_16225	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K9O37_16245	COG0740	serine-type endopeptidase activity
K9O37_16255	COG4774	siderophore transport
K9O37_16265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K9O37_16275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9O37_16275	COG2813	Specifically methylates the guanine in position
K9O37_16380	COG0788	formyltetrahydrofolate deformylase activity
K9O37_16405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K9O37_16405	COG4651	solute:proton antiporter activity
K9O37_16425	COG0724	RNA recognition motif
K9O37_16430	COG0210	DNA helicase
K9O37_16455	COG1733	regulation of RNA biosynthetic process
K9O37_16465	COG2900	Belongs to the SlyX family
K9O37_16470	COG0488	(ABC) transporter
K9O37_16480	COG1280	lysine exporter protein (LysE YggA)
K9O37_16485	COG1560	Kdo2-lipid A biosynthetic process
K9O37_16495	COG1301	dicarboxylic acid transport
K9O37_16550	COG0473	3-isopropylmalate dehydrogenase activity
K9O37_16605	COG0583	DNA-binding transcription factor activity
K9O37_16615	COG0625	glutathione transferase activity
K9O37_16620	COG2378	regulation of single-species biofilm formation
K9O37_16625	COG0546	phosphoglycolate phosphatase activity
K9O37_16635	COG1530	ribonuclease E activity
K9O37_16640	COG0318	PFAM AMP-dependent synthetase and ligase
K9O37_16655	COG0583	DNA-binding transcription factor activity
K9O37_16660	COG4221	oxidoreductase activity
K9O37_16665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K9O37_16675	COG0534	Mate efflux family protein
K9O37_16690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9O37_16730	COG0493	'glutamate synthase
K9O37_16730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9O37_16740	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K9O37_16745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9O37_16760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K9O37_16770	COG0644	oxidoreductase
K9O37_16770	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
K9O37_16780	COG0425	Belongs to the sulfur carrier protein TusA family
K9O37_16785	COG4535	Mg2 and Co2 transporter CorC
K9O37_16795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9O37_16815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K9O37_16820	COG0475	glutathione-regulated potassium exporter activity
K9O37_16820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K9O37_16835	COG0484	heat shock protein binding
K9O37_16840	COG0789	Transcriptional regulator
K9O37_16845	COG0598	Magnesium transport protein CorA
K9O37_16865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9O37_16870	COG1074	ATP-dependent DNA helicase activity
K9O37_16875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
K9O37_16895	COG2226	methyltransferase
K9O37_16915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K9O37_16930	COG2111	Na H antiporter
K9O37_16930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K9O37_16935	COG1006	Multisubunit Na H antiporter MnhC subunit
K9O37_16940	COG0651	ATP synthesis coupled electron transport
K9O37_16945	COG1863	multisubunit Na H antiporter MnhE subunit
K9O37_16950	COG2212	antiporter activity
K9O37_16955	COG1320	monovalent cation:proton antiporter activity
K9O37_17020	COG0237	dephospho-CoA kinase activity
K9O37_17030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9O37_17045	COG0497	DNA recombination
K9O37_17055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K9O37_17085	COG2169	Transcriptional regulator
K9O37_17085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K9O37_17090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K9O37_17165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K9O37_17180	COG0326	Molecular chaperone. Has ATPase activity
K9O37_17195	COG2056	Na+-H+ antiporter family
K9O37_17200	COG0596	Alpha beta hydrolase
K9O37_17295	COG0546	phosphoglycolate phosphatase activity
K9O37_17300	COG1716	ATPase activity
K9O37_17345	COG0181	hydroxymethylbilane synthase activity
K9O37_17355	COG3275	phosphorelay sensor kinase activity
K9O37_17375	COG1538	Outer membrane efflux protein
K9O37_17380	COG0697	spore germination
K9O37_17405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K9O37_17410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K9O37_17415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9O37_17420	COG0772	Belongs to the SEDS family
K9O37_17445	COG4974	Belongs to the 'phage' integrase family
K9O37_17450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9O37_17460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K9O37_17470	COG2197	response regulator
K9O37_17485	COG0793	Belongs to the peptidase S41A family
K9O37_17490	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K9O37_17495	COG0795	lipopolysaccharide-transporting ATPase activity
K9O37_17535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9O37_17535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9O37_17545	COG0004	ammonium transporteR
K9O37_17550	COG0347	Belongs to the P(II) protein family
K9O37_17560	COG0606	chelatase, subunit chli
K9O37_17565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9O37_17575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9O37_17590	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K9O37_17605	COG0318	PFAM AMP-dependent synthetase and ligase
K9O37_17615	COG0477	Major facilitator Superfamily
K9O37_17620	COG2860	membrane
K9O37_17630	COG1253	flavin adenine dinucleotide binding
K9O37_17640	COG0477	Major facilitator Superfamily
K9O37_17650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9O37_17685	COG0655	NAD(P)H dehydrogenase (quinone) activity
K9O37_17695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K9O37_17730	COG1309	transcriptional regulator
K9O37_17765	COG0758	DNA mediated transformation
K9O37_17775	COG0697	spore germination
K9O37_17780	COG1309	transcriptional regulator
K9O37_17795	COG0386	Belongs to the glutathione peroxidase family
K9O37_17805	COG3328	transposase activity
K9O37_17815	COG3335	DDE superfamily endonuclease
K9O37_17880	COG1121	(ABC) transporter
K9O37_17885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K9O37_17890	COG1280	lysine exporter protein (LysE YggA)
K9O37_17895	COG2837	iron assimilation
K9O37_17900	COG0281	malic enzyme
K9O37_17945	COG0519	Catalyzes the synthesis of GMP from XMP
K9O37_17945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K9O37_17950	COG4399	Belongs to the UPF0754 family
K9O37_17955	COG2259	Doxx family
K9O37_17960	COG0586	Pfam SNARE associated Golgi protein
K9O37_17975	COG1192	Involved in chromosome partitioning
K9O37_17985	COG0271	Belongs to the BolA IbaG family
K9O37_18020	COG3321	synthase
K9O37_18020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9O37_18020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K9O37_18020	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
K9O37_18025	COG1960	acyl-CoA dehydrogenase activity
K9O37_18040	COG0477	Major facilitator Superfamily
K9O37_18045	COG1024	Enoyl-CoA hydratase
K9O37_18050	COG1024	Enoyl-CoA hydratase
K9O37_18055	COG1960	acyl-CoA dehydrogenase activity
K9O37_18060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9O37_18080	COG1113	amino acid transport
K9O37_18085	COG1113	amino acid transport
K9O37_18090	COG0251	oxidation-reduction process
K9O37_18130	COG0564	pseudouridine synthase activity
K9O37_18175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K9O37_18190	COG1802	Transcriptional regulator
K9O37_18200	COG1448	Aminotransferase
K9O37_18205	COG0277	FAD linked oxidase domain protein
K9O37_18215	COG2186	Transcriptional regulator
K9O37_18225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9O37_18235	COG3328	transposase activity
K9O37_18240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K9O37_18255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K9O37_18260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K9O37_18270	COG0438	transferase activity, transferring glycosyl groups
K9O37_18280	COG0438	transferase activity, transferring glycosyl groups
K9O37_18285	COG1216	Glycosyl transferase, family 2
K9O37_18285	COG1442	glycosyl transferase family 8
K9O37_18295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K9O37_18300	COG1596	polysaccharide export
K9O37_18325	COG0728	peptidoglycan biosynthetic process
K9O37_18330	COG3023	N-Acetylmuramoyl-L-alanine amidase
K9O37_18385	COG0546	phosphoglycolate phosphatase activity
K9O37_18390	COG1028	Short-chain dehydrogenase reductase Sdr
K9O37_18410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9O37_18415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9O37_18420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9O37_18425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9O37_18430	COG1116	anion transmembrane transporter activity
K9O37_18435	COG1309	transcriptional regulator
K9O37_18440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K9O37_18450	COG0196	riboflavin kinase activity
K9O37_18455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K9O37_18465	COG1047	Peptidyl-prolyl cis-trans
K9O37_18505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K9O37_18510	COG0657	acetylesterase activity
K9O37_18560	COG2951	lytic endotransglycosylase activity
K9O37_18565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K9O37_18580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9O37_18590	COG3328	transposase activity
K9O37_18595	COG0671	phosphoesterase, PA-phosphatase related
K9O37_18600	COG0861	Integral membrane protein TerC family
K9O37_18615	COG0754	glutathionylspermidine amidase activity
K9O37_18625	COG0402	S-adenosylhomocysteine deaminase activity
K9O37_18640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9O37_18645	COG1230	cation diffusion facilitator family transporter
K9O37_18660	COG0706	membrane insertase activity
K9O37_18685	COG0477	Major facilitator Superfamily
K9O37_18765	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
K9O37_18805	COG4772	TonB-dependent receptor
K9O37_18815	COG2801	Transposase and inactivated derivatives
K9O37_18855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9O37_18935	COG1475	DNA binding
K9O37_18940	COG1192	Involved in chromosome partitioning
K9O37_18975	COG0071	Belongs to the small heat shock protein (HSP20) family
K9O37_18980	COG0542	response to heat
K9O37_19025	COG3328	transposase activity
K9O37_19040	COG3706	GGDEF domain
K9O37_19055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9O37_19115	COG0582	viral genome integration into host DNA
K9O37_19170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K9O37_19170	COG0475	glutathione-regulated potassium exporter activity
K9O37_19175	COG3321	synthase
K9O37_19175	COG0604	alcohol dehydrogenase
K9O37_19180	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K9O37_19185	COG0583	DNA-binding transcription factor activity
K9O37_19190	COG4221	oxidoreductase activity
K9O37_19205	COG3328	transposase activity
K9O37_19220	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9O37_19225	COG3657	addiction module killer protein