locus-tag class description ABUW_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ABUW_0004 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABUW_0006 ENOG4105DQR SNARE associated Golgi ABUW_0007 ENOG4105C5H ABC transporter ABUW_0008 ENOG4108821 RND type efflux pump ABUW_0009 ENOG4108821 RND type efflux pump ABUW_0010 ENOG4108821 RND type efflux pump ABUW_0012 ENOG4105D74 hydrolase ABUW_0013 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) ABUW_0014 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) ABUW_0022 ENOG4105C8J )-transporter ABUW_0024 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B ABUW_0029 ENOG4108W5M transcriptional regulator ABUW_0030 ENOG4105C2W permease ABUW_0033 ENOG4108IG5 Transcriptional regulator ABUW_0034 ENOG4105DJY efflux transporter, rnd family, mfp subunit ABUW_0041 ENOG4105F27 Major Facilitator ABUW_0042 ENOG4105CV8 reductase ABUW_0043 ENOG4105HEI LysR family (Transcriptional regulator ABUW_0046 ENOG4105DQ4 alcohol dehydrogenase ABUW_0047 ENOG4108R3E Dna-3-methyladenine glycosylase i ABUW_0050 ENOG4105CEN a g-specific adenine glycosylase ABUW_0054 ENOG4108ZZ3 UPF0260 protein ABUW_0055 ENOG4105D8V Glucose sorbosone dehydrogenase ABUW_0056 ENOG4105D1H recombination factor protein RarA ABUW_0057 ENOG4105S64 Formate nitrite transporter ABUW_0061 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABUW_0062 ENOG4108RWI nicotinamidase ABUW_0063 ENOG4105C09 Bile acid ABUW_0064 ENOG4107QI1 Mate efflux family protein ABUW_0065 ENOG4105EWC Purine nucleoside phosphorylase ABUW_0069 ENOG4108RXX maleylacetoacetate isomerase ABUW_0071 ENOG4105C85 amino acid ABUW_0073 ENOG4105CKI cobalamin synthesis protein ABUW_0075 ENOG4105CZE histidine utilization repressor ABUW_0076 ENOG41090B9 response to stress ABUW_0079 ENOG4105C85 amino acid ABUW_0081 ENOG41088SP formiminoglutamate hydrolase ABUW_0084 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) ABUW_0086 ENOG4105NI8 Cytosine-specific methyltransferase ABUW_0089 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) ABUW_0091 ENOG4108ZAI phosphatidylglycerophosphatase a ABUW_0092 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) ABUW_0095 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) ABUW_0102 ENOG4105KHC sulfurtransferase ABUW_0105 ENOG4105BZU Histidine kinase ABUW_0106 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABUW_0109 ENOG4107QJQ Mate efflux family protein ABUW_0110 ENOG4105CHM Aminotransferase ABUW_0111 ENOG4106BRA Membrane ABUW_0114 ENOG4105D9M gamma-glutamylcysteine synthetase ABUW_0116 ENOG4105CS6 Rhs element vgr protein ABUW_0117 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase ABUW_0123 ENOG4105IPS esterase ABUW_0124 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABUW_0125 ENOG4108Z2U ureidoglycolate hydrolase ABUW_0127 ENOG41061H0 Monooxygenase ABUW_0130 ENOG41084YZ Hydrolase ABUW_0136 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) ABUW_0137 ENOG4105BZU Histidine kinase ABUW_0140 ENOG4105KUZ arsenate reductase ABUW_0141 ENOG4105CGK Exodeoxyribonuclease III ABUW_0145 ENOG4105D7Z glutathione synthase ABUW_0149 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) ABUW_0150 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) ABUW_0151 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) ABUW_0154 ENOG41063SB peptidase ABUW_0155 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) ABUW_0156 ENOG4107QSN dihydrolipoamide acetyltransferase ABUW_0159 ENOG4105E0K tonB-dependent siderophore receptor ABUW_0162 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ABUW_0165 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) ABUW_0167 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) ABUW_0170 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABUW_0171 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase ABUW_0173 ENOG4105D64 Mechanosensitive ion channel ABUW_0175 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ABUW_0176 ENOG4108W2Y isochorismatase ABUW_0178 ENOG4105FBW Monooxygenase ABUW_0179 ENOG4108UZX fmn reductase ABUW_0182 ENOG4105BZU Histidine kinase ABUW_0183 ENOG41062QD Membrane ABUW_0184 ENOG4107QN1 sodium solute ABUW_0186 ENOG4105C94 Transporter ABUW_0188 ENOG4105BZU Histidine kinase ABUW_0189 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) ABUW_0190 ENOG4108WUH Transcriptional regulator, TetR family ABUW_0191 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein ABUW_0193 ENOG4105RA2 Membrane ABUW_0194 ENOG4105DWF phosphomethylpyrimidine kinase ABUW_0196 ENOG4107RDB Major Facilitator ABUW_0197 ENOG4108UUM single-stranded DNA-binding protein ABUW_0199 ENOG4108UMN azlc family ABUW_0201 ENOG4105C85 amino acid ABUW_0203 ENOG4108JPW Aminotransferase ABUW_0204 ENOG4105C26 Dehydrogenase ABUW_0206 ENOG4105CHJ isochorismatase hydrolase ABUW_0207 ENOG4105EUB pirin domain protein ABUW_0213 ENOG4105D94 Major Facilitator Superfamily ABUW_0214 ENOG4106NZI LysR family Transcriptional regulator ABUW_0218 ENOG4105CPC Aldo Keto reductase ABUW_0219 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) ABUW_0224 ENOG4105KVH Transcriptional regulator ABUW_0227 ENOG4105KVH Transcriptional regulator ABUW_0228 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein ABUW_0230 ENOG4108Z9I -acetyltransferase ABUW_0241 ENOG4105CUV Homoserine Kinase ABUW_0249 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) ABUW_0255 ENOG4105CYC Transferase ABUW_0256 ENOG4105E0F Histidine kinase ABUW_0257 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ABUW_0258 ENOG4105BZM domain protein ABUW_0259 ENOG4105CHH sulfate transporter ABUW_0260 ENOG4105PDP Short chain dehydrogenase ABUW_0262 ENOG4105C5H ABC transporter ABUW_0275 ENOG4108IQI permease ABUW_0280 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein ABUW_0283 ENOG4105CJN penicillin-binding protein ABUW_0284 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) ABUW_0285 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) ABUW_0288 ENOG4105DHI Methyltransferase ABUW_0289 ENOG4108JQC penicillin-binding protein 1A ABUW_0294 ENOG4105E4G Type IV pilus ABUW_0298 ENOG4105CBC glutamate synthase ABUW_0299 ENOG4105BZ8 glutamate synthase ABUW_0301 ENOG4108V0P LemA family ABUW_0302 ENOG4105HA9 of methanol dehydrogenase type ABUW_0305 ENOG4108YSG O-Antigen polymerase ABUW_0306 ENOG4108UQY Iron-storage protein ABUW_0308 ENOG4105KME endoribonuclease L-psp ABUW_0309 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ABUW_0311 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) ABUW_0321 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) ABUW_0324 ENOG4107IFA Lipase (EC 3.1.1.3) ABUW_0325 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) ABUW_0326 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) ABUW_0331 ENOG4108JQ1 Dehydrogenase ABUW_0332 ENOG4105CQB FAD linked oxidase domain protein ABUW_0334 ENOG4105VRH Antibiotic biosynthesis monooxygenase ABUW_0335 ENOG4105NF4 modulator of drug activity ABUW_0337 ENOG4107QF7 multi-drug ABUW_0338 ENOG4105EM2 membrane ABUW_0339 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ABUW_0340 ENOG4105IPI Membrane ABUW_0341 ENOG4107SKI cobyrinic Acid a,c-diamide synthase ABUW_0347 ENOG4108IQI permease ABUW_0350 ENOG4105D82 Glutamate dehydrogenase ABUW_0351 ENOG4105C8Y Acetylornithine aminotransferase ABUW_0353 ENOG4105C26 Dehydrogenase ABUW_0358 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin ABUW_0371 ENOG4105W87 Cbs domain ABUW_0372 ENOG41067S9 phage shock protein C, PspC ABUW_0374 ENOG4105CSU acyl-Coa dehydrogenase ABUW_0377 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) ABUW_0380 ENOG4105ECY inositol monophosphatase ABUW_0381 ENOG4105C1J atp-dependent rna helicase ABUW_0383 ENOG4105DHJ ABC, transporter ABUW_0384 ENOG4105CY3 ABC transporter, permease ABUW_0386 ENOG4105E3I toluene tolerance ABUW_0388 ENOG4105D7N magnesium and cobalt transport protein CorA ABUW_0389 ENOG4108URH decarboxylase ABUW_0391 ENOG4105MJ2 Competence protein ABUW_0392 ENOG4105CB5 ATP-dependent DNA helicase recG ABUW_0396 ENOG4105C29 acyl-CoA thioesterase ABUW_0397 ENOG4105CK2 sodium dicarboxylate symporter ABUW_0400 ENOG4105KPV Transcriptional regulator ABUW_0402 ENOG4105D7A ATP-binding protein ABUW_0403 ENOG4105C28 cystathionine ABUW_0404 ENOG41089BK Glutamine amido-transferase ABUW_0426 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) ABUW_0427 ENOG41067V7 50S ribosomal protein L36 ABUW_0429 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) ABUW_0434 ENOG4105C1G acyl-Coa dehydrogenase ABUW_0442 ENOG4105VKU nucleicacid-binding protein ABUW_0443 ENOG4105DGW oligopeptidase A ABUW_0444 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) ABUW_0453 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase ABUW_0454 ENOG4108K2B transcriptional regulator ABUW_0456 ENOG4107S2Z UPF0761 membrane protein ABUW_0457 ENOG4105CS1 NAD(P)H quinone oxidoreductase ABUW_0463 ENOG4105C9A Phoh family ABUW_0465 ENOG4105E4C Lytic transglycosylase catalytic ABUW_0471 ENOG4105D6S protein involved in catabolism of external DNA ABUW_0472 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase ABUW_0481 ENOG4105C1G acyl-Coa dehydrogenase ABUW_0482 ENOG4108RZE Tetr family transcriptional regulator ABUW_0486 ENOG4107QX3 carboxylase ABUW_0487 ENOG4105C1G acyl-Coa dehydrogenase ABUW_0491 ENOG4105KB2 stringent starvation protein b ABUW_0492 ENOG4107MKT Stringent starvation protein a ABUW_0493 ENOG4108UJD 30S ribosomal protein S9 ABUW_0495 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) ABUW_0496 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) ABUW_0497 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) ABUW_0501 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) ABUW_0503 ENOG4107RZC phospholipase d ABUW_0505 ENOG4105UYK outer membrane protein a ABUW_0506 ENOG4108KHX Diguanylate cyclase ABUW_0513 ENOG4107QN2 dihydrolipoyl dehydrogenase ABUW_0515 ENOG4107QPB Beta-lactamase domain protein ABUW_0516 ENOG4107U2T alpha beta ABUW_0518 ENOG4105NAU thioesterase Superfamily protein ABUW_0524 ENOG4105K9H YciI-like protein ABUW_0526 ENOG4105DB7 PHP domain protein ABUW_0527 ENOG4105FFC UPF0187 protein ABUW_0529 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase ABUW_0530 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ABUW_0531 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ABUW_0532 ENOG4105VIE preprotein translocase, subunit YajC ABUW_0541 ENOG41083X2 DNA polymerase III, epsilon subunit ABUW_0542 ENOG4108UUM single-stranded DNA-binding protein ABUW_0551 ENOG4106050 phage regulatory protein, rha family ABUW_0553 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) ABUW_0563 ENOG4108HWY Beta-lactamase ABUW_0575 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase ABUW_0584 ENOG4105ED4 portal protein ABUW_0585 ENOG4105BZU Histidine kinase ABUW_0586 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) ABUW_0587 ENOG4105CM2 brancheD-chain amino acid aminotransferase ABUW_0590 ENOG4107BJW polysaccharide deacetylase ABUW_0592 ENOG4108PQP glycosyl transferase group 1 ABUW_0595 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ABUW_0600 ENOG4105UGU tonB-dependent Receptor ABUW_0604 ENOG4108VY7 phosphate-starvation-inducible protein PsiE ABUW_0605 ENOG4105CSU acyl-Coa dehydrogenase ABUW_0606 ENOG4105CSU acyl-Coa dehydrogenase ABUW_0608 ENOG4105EB3 Histidine kinase ABUW_0609 ENOG4105E3W Two component transcriptional regulator (Winged helix family ABUW_0610 ENOG4105CNG UPF0061 protein ABUW_0614 ENOG4108WBT adenosyltransferase ABUW_0615 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) ABUW_0617 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) ABUW_0624 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase ABUW_0628 ENOG4105D3R alkyl hydroperoxide reductase ABUW_0631 ENOG4105CSH Transporter ABUW_0632 ENOG4108UT2 hemolysin iii ABUW_0634 ENOG41082BV acetyltransferase ABUW_0638 ENOG4105CHU acetyl-coa acetyltransferase ABUW_0639 ENOG4108R6W Transcriptional regulator, ARAC family ABUW_0641 ENOG4105TW1 Carbohydrate-selective porin OprB ABUW_0642 ENOG4105DZG Dehydrogenase ABUW_0643 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) ABUW_0647 ENOG4105CHU acetyl-coa acetyltransferase ABUW_0649 ENOG4108WHA ompa motb domain protein ABUW_0651 ENOG4105E0Y RtcB Protein ABUW_0652 ENOG4108IQI permease ABUW_0654 ENOG4105C2W permease ABUW_0658 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) ABUW_0660 ENOG4108VX5 3-methyladenine DNA glycosylase ABUW_0661 ENOG4105CHB tonB-dependent Receptor ABUW_0662 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABUW_0663 ENOG4108N2Y auxin Efflux ABUW_0665 ENOG4105T95 Thiol disulfide interChange protein ABUW_0666 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) ABUW_0668 ENOG4105K78 MarR family Transcriptional regulator ABUW_0669 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA ABUW_0673 ENOG4105KWI UPF0339 protein ABUW_0678 ENOG4108UNF response regulator ABUW_0679 ENOG4105M3Z response regulator ABUW_0680 ENOG4108ZGA chew protein ABUW_0681 ENOG4105C8Q Methyl-accepting chemotaxis ABUW_0682 ENOG4105CBS Chea signal transduction histidine kinase ABUW_0684 ENOG4105D4P Coproporphyrinogen iii oxidase ABUW_0687 ENOG4106HKS Entericidin EcnA/B family ABUW_0689 ENOG4105WD1 Membrane ABUW_0690 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ABUW_0698 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) ABUW_0700 ENOG4105EM2 membrane ABUW_0701 ENOG4105C2C drug resistance transporter, Bcr CflA ABUW_0704 ENOG4105BZG amino acid carrier protein ABUW_0705 ENOG4105D78 K07001 NTE family protein ABUW_0706 ENOG4105C7B Threonine dehydratase ABUW_0712 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) ABUW_0714 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) ABUW_0715 ENOG4105DFF Rod shape-determining protein mreb ABUW_0716 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) ABUW_0717 ENOG4105VQ7 Rod shape-determining protein MreD ABUW_0718 ENOG4108Z03 MAF-like protein ABUW_0719 ENOG4105C03 ribonuclease ABUW_0721 ENOG4105D8T Acyltransferase ABUW_0723 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein ABUW_0725 ENOG4108X0B nad(p)h dehydrogenase (quinone) ABUW_0730 ENOG4105CF7 AraC family transcriptional regulator ABUW_0752 ENOG4105CDU Replicative dna helicase ABUW_0762 ENOG4105MEW serine threonine protein phosphatase ABUW_0795 ENOG4105UPP uncharacterized protein ydcA ABUW_0817 ENOG4105C85 amino acid ABUW_0818 ENOG4105C7F AcnD-accessory protein PrpF ABUW_0819 ENOG4105CTB Polyprenyl synthetase ABUW_0820 ENOG4105MSB protein, conserved in bacteria ABUW_0823 ENOG4105D78 K07001 NTE family protein ABUW_0827 ENOG4105DIJ Phosphoethanolamine transferase ABUW_0828 ENOG4105XJC Two component transcriptional regulator (Winged helix family ABUW_0829 ENOG4105DHQ Histidine kinase ABUW_0832 ENOG4108M0I Transcriptional regulator ABUW_0836 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) ABUW_0840 ENOG4105K8R UPF0145 protein ABUW_0841 ENOG4105K8R UPF0145 protein ABUW_0842 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ABUW_0843 ENOG4105BZS acriflavin resistance protein ABUW_0844 ENOG4105C1P efflux transporter, rnd family, mfp subunit ABUW_0845 ENOG410841Q phosphoesterase PA-phosphatase related protein ABUW_0850 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) ABUW_0853 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ABUW_0854 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) ABUW_0855 ENOG4105KVH Transcriptional regulator ABUW_0857 ENOG4105CUB amino acid ABUW_0860 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) ABUW_0861 ENOG41084BA UPF0250 protein ABUW_0862 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABUW_0868 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit ABUW_0869 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein ABUW_0871 ENOG4105E33 succinate dehydrogenase ABUW_0872 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 ABUW_0873 ENOG4105C7S Dehydrogenase ABUW_0874 ENOG4107QN2 dihydrolipoyl dehydrogenase ABUW_0876 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha ABUW_0882 ENOG4105CKW Inner membrane protein yedI ABUW_0883 ENOG4105CGZ zinc metallopeptidase ABUW_0884 ENOG4105EEQ Na H antiporter ABUW_0887 ENOG4105PNM synthesis protein ABUW_0890 ENOG41080TK Universal stress protein ABUW_0893 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain ABUW_0894 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain ABUW_0897 ENOG4105HBR Rna-binding protein ABUW_0899 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) ABUW_0900 ENOG4105EEI dihydropteroate synthase ABUW_0910 ENOG4105CSH Transporter ABUW_0911 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) ABUW_0912 ENOG4105C6V Glycerol-3-phosphate dehydrogenase ABUW_0915 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) ABUW_0919 ENOG41080IJ Diacylglycerol kinase ABUW_0921 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase ABUW_0922 ENOG4105BZS acriflavin resistance protein ABUW_0925 ENOG4105E4C Lytic transglycosylase catalytic ABUW_0929 ENOG4108RRZ Transcription elongation factor GreB ABUW_0932 ENOG4105CEY Amp-dependent synthetase and ligase ABUW_0943 ENOG4105BZW Glycerate kinase ABUW_0944 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit ABUW_0945 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) ABUW_0948 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) ABUW_0950 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) ABUW_0951 ENOG4105C85 amino acid ABUW_0953 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) ABUW_0955 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) ABUW_0956 ENOG4105N14 lysine exporter protein LysE YggA ABUW_0957 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABUW_0958 ENOG4105BZJ Electron transfer flavoprotein ABUW_0959 ENOG4105C10 Electron transfer flavoprotein ABUW_0960 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABUW_0967 ENOG4107KET secretion protein, HlyD family ABUW_0974 ENOG4105D60 lipoprotein releasing system transmembrane protein ABUW_0975 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) ABUW_0976 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 ABUW_0978 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) ABUW_0979 ENOG4107R6F Alpha Beta Hydrolase Fold protein ABUW_0980 ENOG4108V3E phosphoribosylglycinamide formyltransferase ABUW_0982 ENOG4105C02 permease ABUW_0992 ENOG4105KCK Peptidoglycan-associated lipoprotein ABUW_0993 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) ABUW_0995 ENOG4105M8F Biopolymer transport protein exbD tolR ABUW_0996 ENOG4105E02 MotA TolQ exbB proton channel ABUW_0997 ENOG4107YD3 Thioesterase ABUW_0998 ENOG4105CH2 amidohydrolase ABUW_1002 ENOG4108ETH Formylglycinamide ribotide synthetase ABUW_1003 ENOG4105C2C drug resistance transporter, Bcr CflA ABUW_1005 ENOG4105EGD dinuclear metal center protein, YbgI family ABUW_1006 ENOG4108UKI Enoyl-CoA hydratase ABUW_1009 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ABUW_1012 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) ABUW_1013 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) ABUW_1016 ENOG4107R11 Transcriptional regulator ABUW_1017 ENOG4108IJ6 ABC transporter ABUW_1019 ENOG4108I5D sulfate abc transporter ABUW_1021 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein ABUW_1022 ENOG4105YAZ 4-amino-4-deoxychorismate lyase ABUW_1023 ENOG4105HHA aminodeoxychorismate lyase ABUW_1026 ENOG4108IYU L-aspartate oxidase ABUW_1027 ENOG4105C0H protease ABUW_1030 ENOG4105C3F Signal peptidase i ABUW_1033 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) ABUW_1035 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) ABUW_1036 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) ABUW_1037 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase ABUW_1038 ENOG4105EMU Dehydrogenase ABUW_1045 ENOG4105BZU Histidine kinase ABUW_1047 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) ABUW_1049 ENOG4105DTR rard protein ABUW_1056 ENOG4107QS8 (LipO)protein ABUW_1057 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ABUW_1058 ENOG4105EA8 2-Nitropropane dioxygenase ABUW_1064 ENOG4107R8N Glycosyl transferase, family 2 ABUW_1067 ENOG4105CVP deoxyribo-dipyrimidine photolyase ABUW_1068 ENOG4108YZY peptidylprolyl cis-trans isomerase ABUW_1069 ENOG4105CEP NADH dehydrogenase ABUW_1070 ENOG4105DZ1 carboxypeptidase ABUW_1072 ENOG4105E9K Isocitrate dehydrogenase ABUW_1073 ENOG4108R99 pseudouridine synthase ABUW_1078 ENOG4105CBP Major Facilitator ABUW_1079 ENOG4105EGI Transcriptional regulator ABUW_1080 ENOG4108ETY sodium dicarboxylate symporter ABUW_1081 ENOG4105JAB phenazine biosynthesis protein, phzf family ABUW_1088 ENOG4107IIZ CRISPR-associated helicase, Cas3 ABUW_1089 ENOG4105ENG CRISPR-associated protein, Csy1 family ABUW_1091 ENOG4105M6W Crispr-associated protein, Csy3 family ABUW_1097 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) ABUW_1100 ENOG4105D3G Pseudouridine synthase ABUW_1101 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) ABUW_1104 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ABUW_1109 ENOG4108JPW Aminotransferase ABUW_1110 ENOG4105DY8 decarboxylase ABUW_1112 ENOG4105F7P transcriptional regulator AsnC family ABUW_1113 ENOG4107RA9 decarboxylase ABUW_1114 ENOG4105C85 amino acid ABUW_1115 ENOG4105CVA phosphate ABUW_1116 ENOG4105C8U phosphate abc transporter ABUW_1118 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) ABUW_1119 ENOG4105ERU peptidase ABUW_1122 ENOG4107QTF adenylosuccinate lyase ABUW_1126 ENOG4108Z0R Transferase ABUW_1127 ENOG4105DZ1 carboxypeptidase ABUW_1131 ENOG4108K5P (LipO)protein ABUW_1132 ENOG4105EJC lysr family transcriptional regulator ABUW_1133 ENOG4105DAN ATP-dependent protease ABUW_1136 ENOG4105DHU Bile acid ABUW_1138 ENOG41066DG (EAL) domain protein ABUW_1140 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein ABUW_1142 ENOG4105D22 carbon starvation protein ABUW_1143 ENOG4105VCD cytoplasmic protein ABUW_1145 ENOG4105ETT transcriptional Regulator, LysR family ABUW_1146 ENOG4105H1N peptidase, M24 ABUW_1147 ENOG4105C94 Transporter ABUW_1148 ENOG4105C94 Transporter ABUW_1150 ENOG4105C26 Dehydrogenase ABUW_1151 ENOG4107QZF nitrite reductase NADPH large subunit ABUW_1152 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) ABUW_1158 ENOG41060M8 Pfam:PhdYeFM ABUW_1165 ENOG4105C2I pirin domain protein ABUW_1167 ENOG4105WWK YheO domain protein ABUW_1170 ENOG4105CEY Amp-dependent synthetase and ligase ABUW_1175 ENOG4108IPW abc transporter atp-binding protein ABUW_1179 ENOG4105C0W non-ribosomal peptide synthetase ABUW_1180 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase ABUW_1181 ENOG4105WQI isochorismatase ABUW_1184 ENOG4105BZ1 (ABC) transporter ABUW_1185 ENOG4108JJ7 ABC transporter ABUW_1188 ENOG4105E4F Isochorismate synthase ABUW_1191 ENOG4105NX3 Membrane ABUW_1195 ENOG4105EUJ GTP cyclohydrolase i ABUW_1197 ENOG4105C7W Xanthine dehydrogenase ABUW_1203 ENOG4105CD8 aminopeptidase N ABUW_1204 ENOG4105DDQ anthranilate synthase ABUW_1206 ENOG4105DUX Transporter ABUW_1207 ENOG4105C5F glutamine synthetase ABUW_1209 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) ABUW_1216 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ABUW_1217 ENOG4107QNR UPF0135 protein ABUW_1218 ENOG4105C0H protease ABUW_1220 ENOG4105C6K Malic enzyme ABUW_1221 ENOG4105BZU Histidine kinase ABUW_1222 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) ABUW_1223 ENOG4105SYT Methylenetetrahydrofolate reductase ABUW_1224 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) ABUW_1227 ENOG4107QPN acyl-Coa dehydrogenase ABUW_1228 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) ABUW_1229 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) ABUW_1232 ENOG4107RNU major facilitator superfamily MFS_1 ABUW_1234 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ABUW_1235 ENOG4105CE9 30S ribosomal protein S2 ABUW_1243 ENOG4105CVE Lytic murein transglycosylase ABUW_1244 ENOG4105CNI cell division protein FtsW ABUW_1247 ENOG4105E3A (ABC) transporter ABUW_1248 ENOG4105DA5 (ABC) transporter ABUW_1257 ENOG41076J9 exonuclease VIII ABUW_1271 ENOG4105CDU Replicative dna helicase ABUW_1316 ENOG4105DR5 peptidase ABUW_1334 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ABUW_1336 ENOG4105ENT Efflux transporter rnd family, mfp subunit ABUW_1339 ENOG4105E89 ABC transporter ABUW_1340 ENOG4105DSP amino acid AbC transporter ABUW_1341 ENOG4106YG3 ABC transporter ABUW_1344 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding ABUW_1345 ENOG4105CFP Peptidase U32 ABUW_1346 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABUW_1347 ENOG4105JAB phenazine biosynthesis protein, phzf family ABUW_1348 ENOG4105DP0 ferredoxin-NADP reductase ABUW_1349 ENOG4108R96 Methyltransferase, YaeB family ABUW_1351 ENOG4107QHF type ii secretion system protein e ABUW_1353 ENOG4105XJC Two component transcriptional regulator (Winged helix family ABUW_1354 ENOG4105DHQ Histidine kinase ABUW_1356 ENOG4105M6F mutator MutT protein ABUW_1358 ENOG4105BZ4 penicillin-binding protein ABUW_1359 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) ABUW_1360 ENOG4105VUT cytoplasmic protein ABUW_1361 ENOG4107QYG anthranilate phosphoribosyltransferase ABUW_1362 ENOG4105CK2 sodium dicarboxylate symporter ABUW_1363 ENOG4105C1G acyl-Coa dehydrogenase ABUW_1364 ENOG4105NIV Esterase ABUW_1365 ENOG4105CQC Prephenate dehydratase ABUW_1366 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase ABUW_1368 ENOG4105CIN aminoacyl-histidine dipeptidase ABUW_1369 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) ABUW_1374 ENOG4105M08 Membrane ABUW_1375 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABUW_1377 ENOG4105VEQ Cold shock protein ABUW_1378 ENOG4105C1J atp-dependent rna helicase ABUW_1380 ENOG41069NU Nitroreductase ABUW_1385 ENOG4105D5G Transposase ABUW_1400 ENOG4105RDA repressor ABUW_1446 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase ABUW_1449 ENOG4105C5I Dehydrogenase ABUW_1450 ENOG4105ERG peptidase m48, ste24p ABUW_1451 ENOG4105KTH gatB Yqey ABUW_1452 ENOG4105VCC 30S ribosomal protein S21 ABUW_1457 ENOG4105D9P serine threonine protein kinase ABUW_1462 ENOG4105EVZ LysR family transcriptional regulator ABUW_1463 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ABUW_1464 ENOG4105C26 Dehydrogenase ABUW_1471 ENOG4105H4F exported protein ABUW_1477 ENOG4105D6U Sodium Glutamate Symporter ABUW_1479 ENOG4107RSM transcriptional regulator ABUW_1481 ENOG4105EWI Short-chain dehydrogenase reductase Sdr ABUW_1484 ENOG4105JXH GntR family transcriptional regulator ABUW_1496 ENOG4105CSH Transporter ABUW_1501 ENOG4105F1S paraquat-inducible protein a ABUW_1502 ENOG4105DY2 Paraquat-inducible protein b ABUW_1504 ENOG4105VT2 5-hydroxyisourate hydrolase ABUW_1512 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase ABUW_1514 ENOG4105DHQ Histidine kinase ABUW_1515 ENOG4105ETX regulatoR ABUW_1525 ENOG4105CK2 sodium dicarboxylate symporter ABUW_1527 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) ABUW_1528 ENOG4108UMI ABC transporter, permease ABUW_1529 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ABUW_1531 ENOG4105C12 Phosphoribosylglycinamide synthetase ABUW_1532 ENOG4105DC1 bifunctional purine biosynthesis protein purh ABUW_1533 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) ABUW_1544 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ABUW_1545 ENOG4105CDU Replicative dna helicase ABUW_1550 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) ABUW_1551 ENOG4105CCU oxidase (Subunit III) ABUW_1552 ENOG4105BZ9 Cytochrome C oxidase, subunit I ABUW_1553 ENOG4105E2S oxidase) subunit II ABUW_1558 ENOG4107BJW polysaccharide deacetylase ABUW_1559 ENOG4105CND Glycosyl transferase, family 2 ABUW_1560 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD ABUW_1562 ENOG4105DEN Luciferase family ABUW_1565 ENOG4105CC0 LysR family Transcriptional regulator ABUW_1568 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) ABUW_1569 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ABUW_1570 ENOG4105GVF (ABC) transporter ABUW_1573 ENOG4105C1G acyl-Coa dehydrogenase ABUW_1575 ENOG4108MEJ flavin reductase domain protein ABUW_1576 ENOG4105D06 uba thif-type nad fad binding protein ABUW_1581 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) ABUW_1582 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) ABUW_1584 ENOG4105C08 Histidine kinase ABUW_1585 ENOG4105EEX Two component transcriptional regulator (Winged helix family ABUW_1586 ENOG4105CFQ glutamine synthetase ABUW_1589 ENOG4107S74 Lysophospholipid transporter LplT ABUW_1590 ENOG4105CFU surface antigen ABUW_1593 ENOG4107QIJ Aconitate hydratase 2 ABUW_1595 ENOG4105EYW Ion transport protein ABUW_1596 ENOG4105F27 Major Facilitator ABUW_1599 ENOG4105DZ2 Transcriptional regulator ABUW_1606 ENOG4105K8N protein family UPF0079, ATPase ABUW_1607 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) ABUW_1609 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) ABUW_1610 ENOG4108TZV Membrane ABUW_1611 ENOG4108RCM Nitroreductase ABUW_1617 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) ABUW_1618 ENOG4107FQ9 ethanolamine ammonia-lyase ABUW_1619 ENOG4105CPD ethanolamine ammonia-lyase ABUW_1620 ENOG4107R55 ethanolamine transporter ABUW_1622 ENOG4107RR1 TRANSCRIPTIONal ABUW_1624 ENOG4105C0A alcohol dehydrogenase ABUW_1625 ENOG4107QUV Domain protein ABUW_1630 ENOG4105CD8 aminopeptidase N ABUW_1633 ENOG4108D1K outer membrane usher protein ABUW_1638 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) ABUW_1639 ENOG4105EW9 transcriptional regulator AsnC family ABUW_1642 ENOG4105CAT Cytidine monophosphate kinase ABUW_1645 ENOG4105R8C Transcriptional regulator ABUW_1648 ENOG4105CUY Mechanosensitive ion channel ABUW_1655 ENOG4105CNM Receptor ABUW_1660 ENOG4105C5H ABC transporter ABUW_1661 ENOG41081QV Universal stress protein ABUW_1666 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic ABUW_1668 ENOG4105DKK Benzoate ABUW_1669 ENOG4105EW9 transcriptional regulator AsnC family ABUW_1670 ENOG4108NIW Leucine export protein LeuE ABUW_1671 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ABUW_1672 ENOG4105C5Q Transcriptional regulator ABUW_1674 ENOG4105CHU acetyl-coa acetyltransferase ABUW_1675 ENOG4105CHR reductase ABUW_1680 ENOG4107QMP dna polymerase iii subunits gamma and tau ABUW_1682 ENOG4105HSS phospholipase C ABUW_1684 ENOG4105C0A alcohol dehydrogenase ABUW_1690 ENOG4105CBC glutamate synthase ABUW_1694 ENOG4105D8G Major Facilitator superfamily ABUW_1696 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ABUW_1697 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein ABUW_1702 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABUW_1704 ENOG4107QZF nitrite reductase NADPH large subunit ABUW_1705 ENOG4108IFG nitrite reductase, (NAD(P)H) ABUW_1712 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) ABUW_1713 ENOG4105CVM Molybdenum cofactor synthesis domain protein ABUW_1716 ENOG4105T38 integral membrane protein ABUW_1720 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) ABUW_1721 ENOG4105CMR udp-glucose 4-epimerase ABUW_1732 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ABUW_1733 ENOG4105CUX Signal transduction histidine kinase ABUW_1737 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) ABUW_1738 ENOG4105KNE Phosphatidate cytidylyltransferase ABUW_1740 ENOG4105DZP Membrane-associated zinc metalloprotease ABUW_1745 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) ABUW_1747 ENOG4105Y3E Modulates RecA activity (By similarity) ABUW_1749 ENOG4105VEJ Heat shock protein ABUW_1750 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 ABUW_1755 ENOG4105F7P transcriptional regulator AsnC family ABUW_1757 ENOG4105C85 amino acid ABUW_1760 ENOG4105CHH sulfate transporter ABUW_1761 ENOG4108RAV Conserved protein ABUW_1762 ENOG4105D8V Glucose sorbosone dehydrogenase ABUW_1764 ENOG4105BZU Histidine kinase ABUW_1770 ENOG4105DM4 PTS System ABUW_1771 ENOG4105DE4 1-phosphofructokinase ABUW_1772 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ABUW_1777 ENOG4105CWM branched-chain amino acid transport system II carrier protein ABUW_1778 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ABUW_1779 ENOG4105CC0 LysR family Transcriptional regulator ABUW_1781 ENOG4105M2J Glutaredoxin ABUW_1782 ENOG4105C8Y Acetylornithine aminotransferase ABUW_1783 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ABUW_1789 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ABUW_1791 ENOG41068P6 UPF0319 protein ABUW_1794 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ABUW_1795 ENOG4105C4M (Ubiquinol oxidase) subunit I ABUW_1797 ENOG4105PV3 Inner membrane protein yqiJ ABUW_1800 ENOG4105E0K tonB-dependent siderophore receptor ABUW_1803 ENOG4105HDD phospholipase ABUW_1804 ENOG4105CZN Potassium uptake protein ABUW_1806 ENOG4105C7B Threonine dehydratase ABUW_1813 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) ABUW_1814 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ABUW_1816 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ABUW_1819 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABUW_1828 ENOG4107VMU Membrane ABUW_1829 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) ABUW_1831 ENOG4107QP7 CoA-transferase subunit A ABUW_1832 ENOG4107QNJ CoA-transferase subunit B ABUW_1833 ENOG4105CHU acetyl-coa acetyltransferase ABUW_1834 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase ABUW_1835 ENOG4105F2Z 3-oxoadipate enol-lactonase ABUW_1836 ENOG4105D2S major facilitator superfamily ABUW_1837 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase ABUW_1838 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta ABUW_1839 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha ABUW_1840 ENOG4105FF2 Type I DHQase ABUW_1841 ENOG4106JPM 3-dehydroshikimate dehydratase ABUW_1842 ENOG4105TW1 Carbohydrate-selective porin OprB ABUW_1843 ENOG4105DZG Dehydrogenase ABUW_1845 ENOG4105MD1 YeeE YedE family protein ABUW_1848 ENOG4107HP6 Transcriptional regulator ABUW_1849 ENOG4108PTX LysR family Transcriptional regulator ABUW_1850 ENOG4105C1G acyl-Coa dehydrogenase ABUW_1855 ENOG4105DNH Major Facilitator ABUW_1857 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) ABUW_1861 ENOG4105FUY alpha subunit ABUW_1863 ENOG4105CHR reductase ABUW_1867 ENOG4105F11 amine oxidase ABUW_1869 ENOG4105C26 Dehydrogenase ABUW_1871 ENOG4105F2Z 3-oxoadipate enol-lactonase ABUW_1872 ENOG4105CHU acetyl-coa acetyltransferase ABUW_1873 ENOG4107QNJ CoA-transferase subunit B ABUW_1874 ENOG4107QP7 CoA-transferase subunit A ABUW_1876 ENOG4105NN7 muconolactone delta-isomerase ABUW_1877 ENOG4105DTQ mandelate racemase muconate lactonizing ABUW_1878 ENOG4108KB2 LysR family Transcriptional regulator ABUW_1880 ENOG4107EJG GntR family transcriptional regulator ABUW_1884 ENOG4105CZJ Aldehyde dehydrogenase ABUW_1887 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABUW_1895 ENOG4107Z3H Transcriptional regulator, TetR family ABUW_1896 ENOG4108ZX5 transcriptional regulator ABUW_1897 ENOG4105EMU Dehydrogenase ABUW_1898 ENOG4107GD3 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity) ABUW_1900 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABUW_1905 ENOG4105CHJ isochorismatase hydrolase ABUW_1906 ENOG4105EJC lysr family transcriptional regulator ABUW_1907 ENOG4105D8V Glucose sorbosone dehydrogenase ABUW_1908 ENOG4105CKD glutathione-regulated potassium-efflux system protein ABUW_1910 ENOG4105CH2 amidohydrolase ABUW_1924 ENOG4105FDP GntR family transcriptional regulator ABUW_1927 ENOG4106KR7 LysR family Transcriptional regulator ABUW_1930 ENOG4105CW7 secretion protein, HlyD family ABUW_1933 ENOG4105CZJ Aldehyde dehydrogenase ABUW_1934 ENOG4105C01 Dihydroxy-acid dehydratase ABUW_1936 ENOG4105DDW LysR family Transcriptional regulator ABUW_1937 ENOG4105EXW epimerase dehydratase ABUW_1939 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ABUW_1942 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ABUW_1955 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) ABUW_1958 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) ABUW_1965 ENOG4105ENX hydrolase ABUW_1966 ENOG4105EQ2 LysR family Transcriptional regulator ABUW_1967 ENOG4108BAS reductase ABUW_1970 ENOG4108R6W Transcriptional regulator, ARAC family ABUW_1972 ENOG4105E0F Histidine kinase ABUW_1973 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABUW_1974 ENOG4105C1P efflux transporter, rnd family, mfp subunit ABUW_1975 ENOG4105BZS acriflavin resistance protein ABUW_1976 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ABUW_1978 ENOG4105CT3 Monooxygenase ABUW_1980 ENOG4105CJP fad dependent oxidoreductase ABUW_2052 ENOG4105X0I Fimbrial ABUW_2062 ENOG4107RZC phospholipase d ABUW_2066 ENOG4108IGT Dipeptidase ABUW_2073 ENOG4107T31 5'-nucleotidase ABUW_2075 ENOG4105WQI isochorismatase ABUW_2076 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase ABUW_2077 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) ABUW_2078 ENOG4105E0C molybdate abc transporter ABUW_2079 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein ABUW_2080 ENOG4105F4R Transcriptional regulator mode ABUW_2081 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit ABUW_2082 ENOG4108YS2 small subunit ABUW_2083 ENOG4105F57 Anthranilate dioxygenase reductase ABUW_2088 ENOG4105CHR reductase ABUW_2090 ENOG4105D2S major facilitator superfamily ABUW_2091 ENOG4105CF7 AraC family transcriptional regulator ABUW_2092 ENOG4105DTD Dehydrogenase ABUW_2093 ENOG4105CY2 Citrate transporter ABUW_2095 ENOG4108M0I Transcriptional regulator ABUW_2098 ENOG4105CRW Short chain fatty acid transporter ABUW_2099 ENOG4105CHU acetyl-coa acetyltransferase ABUW_2101 ENOG4107YNJ LysR family Transcriptional regulator ABUW_2104 ENOG4108IJ0 Aspartate ammonia-lyase ABUW_2106 ENOG4105CSH Transporter ABUW_2110 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ABUW_2111 ENOG4106FTQ Taurine ABC transporter, periplasmic ABUW_2114 ENOG4105FDP GntR family transcriptional regulator ABUW_2116 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) ABUW_2117 ENOG4105KVH Transcriptional regulator ABUW_2118 ENOG4105UEI Transcriptional Regulator AraC Family ABUW_2121 ENOG4108VCT Sulfite exporter TauE/SafE ABUW_2123 ENOG4107S76 domain protein ABUW_2125 ENOG4105FFC UPF0187 protein ABUW_2127 ENOG4105CHR reductase ABUW_2130 ENOG4105CPP Dehydrogenase, E1 component ABUW_2131 ENOG4107R0V Pyruvate dehydrogenase ABUW_2132 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) ABUW_2135 ENOG4105BZU Histidine kinase ABUW_2137 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) ABUW_2138 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) ABUW_2147 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) ABUW_2150 ENOG4105C28 cystathionine ABUW_2152 ENOG4105F2W methyltransferase ABUW_2159 ENOG4105K59 histidine triad (HIT) protein ABUW_2164 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) ABUW_2165 ENOG4105CNM Receptor ABUW_2169 ENOG4107TSN permease ABUW_2170 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ABUW_2173 ENOG4107TB6 phosphoglycerate mutase ABUW_2174 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) ABUW_2175 ENOG4108YZT Adenosylcobinamide kinase ABUW_2177 ENOG4107VXZ Hydrolase ABUW_2183 ENOG4105JSC dimethylmenaquinone methyltransferase ABUW_2185 ENOG4105DJU Siderophore biosynthesis protein ABUW_2186 ENOG4105DUU IucA IucC family protein ABUW_2187 ENOG4105C0R drug resistance transporter emrb qaca subfamily ABUW_2190 ENOG4108Z66 YbaK ebsC protein ABUW_2193 ENOG4105C1G acyl-Coa dehydrogenase ABUW_2194 ENOG4105C1G acyl-Coa dehydrogenase ABUW_2195 ENOG4105EEF Alkane 1-monooxygenase ABUW_2196 ENOG4105E7U AraC family transcriptional regulator ABUW_2197 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) ABUW_2198 ENOG4105K70 DNA-binding protein ABUW_2201 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family ABUW_2203 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins ABUW_2204 ENOG4108Z4V iron-sulfur cluster assembly ABUW_2207 ENOG4108ZIT Ferredoxin, 2FE-2S ABUW_2208 ENOG4105F8J Adenylate Guanylate cyclase ABUW_2210 ENOG4108JA2 transcriptioN-repair coupling factor ABUW_2214 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) ABUW_2215 ENOG4105K4T epimerase ABUW_2218 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase ABUW_2222 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ABUW_2224 ENOG4105DGW oligopeptidase A ABUW_2229 ENOG4108DNJ Pfam:TonB ABUW_2232 ENOG4105SG9 biopolymer transport protein, ExbD ABUW_2234 ENOG4107QP3 malate synthase g ABUW_2235 ENOG4105D6Z AFG1 family ATPase ABUW_2237 ENOG4107RN6 Monooxygenase ABUW_2241 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) ABUW_2242 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) ABUW_2245 ENOG4108Z6B deaminase ABUW_2249 ENOG4108RTD type II secretion system protein K ABUW_2254 ENOG4105F8V Hydrolase, tatD family ABUW_2256 ENOG4107QRG dna polymerase iii ABUW_2258 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) ABUW_2259 ENOG4105BZ1 (ABC) transporter ABUW_2262 ENOG4105FA0 parb-like partition protein ABUW_2263 ENOG4107QJE Chromosome Partitioning Protein ABUW_2265 ENOG4108S0S Nucleotidyl transferase ABUW_2266 ENOG4105EHM Aminoglycoside phosphotransferase ABUW_2267 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) ABUW_2268 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) ABUW_2269 ENOG4105D2N Aldolase ABUW_2273 ENOG4108UHJ MAF-like protein ABUW_2274 ENOG4105EZE Cupin 4 family protein ABUW_2276 ENOG41080HT Transcriptional regulator, arsr family ABUW_2278 ENOG4105XPP Protein of unknown function (DUF1275) ABUW_2279 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme ABUW_2280 ENOG4105BZ1 (ABC) transporter ABUW_2282 ENOG4108ZX5 transcriptional regulator ABUW_2284 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) ABUW_2285 ENOG4105CK7 Sodium proline symporter ABUW_2286 ENOG4105EW9 transcriptional regulator AsnC family ABUW_2287 ENOG4105C26 Dehydrogenase ABUW_2288 ENOG4105YGK Pfam:UPF0157 ABUW_2291 ENOG4108T58 Mg2 transport protein CorA ABUW_2293 ENOG4108YYC ycei family ABUW_2295 ENOG4105CV1 Transketolase (EC 2.2.1.1) ABUW_2300 ENOG4108HWY Beta-lactamase ABUW_2305 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) ABUW_2306 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) ABUW_2310 ENOG4105X0I Fimbrial ABUW_2311 ENOG4105GQR Chaperone ABUW_2316 ENOG4108IPJ Membrane ABUW_2318 ENOG4105ETS cytosine purines uracil thiamine allantoin ABUW_2320 ENOG4105CC0 LysR family Transcriptional regulator ABUW_2325 ENOG41067SE Tetr family transcriptional regulator ABUW_2328 ENOG4105EW9 transcriptional regulator AsnC family ABUW_2330 ENOG4105CDA abc transporter atp-binding protein ABUW_2331 ENOG4105DRP amino acid AbC transporter ABUW_2332 ENOG4105EAD ABC transporter ABUW_2335 ENOG4107T8P acyl-Coa dehydrogenase ABUW_2338 ENOG4105D01 (LipO)protein ABUW_2339 ENOG4105D01 (LipO)protein ABUW_2340 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ABUW_2341 ENOG4108UMI ABC transporter, permease ABUW_2342 ENOG4105C3G gtp-binding protein ABUW_2347 ENOG4108UMN azlc family ABUW_2348 ENOG4105ZED uncharacterized protein ygaH ABUW_2354 ENOG4105E7U AraC family transcriptional regulator ABUW_2355 ENOG4108V06 Glutathione peroxidase ABUW_2357 ENOG4105CHM Aminotransferase ABUW_2358 ENOG4105CK2 sodium dicarboxylate symporter ABUW_2360 ENOG4105C0B DNA polymerase III (alpha subunit) ABUW_2365 ENOG4108JU3 Alkyl hydroperoxide reductase ABUW_2368 ENOG4108KB2 LysR family Transcriptional regulator ABUW_2369 ENOG4105D6J arsenicaL-resistance protein ABUW_2370 ENOG41082YX Transcriptional regulator, arsr family ABUW_2373 ENOG4105CPN adenine deaminase ABUW_2375 ENOG4105CBN LysR family transcriptional regulator ABUW_2377 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease ABUW_2379 ENOG4105E2B Taurine dioxygenase ABUW_2380 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component ABUW_2381 ENOG4108IY8 ABC, transporter ABUW_2382 ENOG4106FTQ Taurine ABC transporter, periplasmic ABUW_2384 ENOG4105C54 Major Facilitator superfamily ABUW_2389 ENOG4105C4M (Ubiquinol oxidase) subunit I ABUW_2390 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ABUW_2392 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABUW_2393 ENOG4108K70 Transcriptional regulator ABUW_2396 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ABUW_2400 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) ABUW_2401 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase ABUW_2403 ENOG4105DXI Major Facilitator superfamily ABUW_2406 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABUW_2407 ENOG41067MG lrgb family ABUW_2408 ENOG4105VAW lrga family ABUW_2409 ENOG4105CMU LysR family (Transcriptional regulator ABUW_2410 ENOG4108SHQ Glutathione S-transferase ABUW_2411 ENOG4105CYM Glutathione S-transferase ABUW_2412 ENOG4105CBN LysR family transcriptional regulator ABUW_2413 ENOG4105CHR reductase ABUW_2415 ENOG4105D7W serine acetyltransferase ABUW_2416 ENOG4105ESN nucleotide-binding protein ABUW_2417 ENOG4105C9B Cysteine desulfurase ABUW_2419 ENOG4105EXG Transcriptional regulator ABUW_2420 ENOG4105CT1 (ABC) transporter ABUW_2421 ENOG4107RP9 extracellular solute-binding protein, family 3 ABUW_2422 ENOG4105CDA abc transporter atp-binding protein ABUW_2423 ENOG4108HW4 amino acid AbC transporter ABUW_2424 ENOG4105EAD ABC transporter ABUW_2426 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase ABUW_2427 ENOG4105BZU Histidine kinase ABUW_2429 ENOG4105EW9 transcriptional regulator AsnC family ABUW_2435 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ABUW_2446 ENOG4105HEI LysR family (Transcriptional regulator ABUW_2450 ENOG4105CEY Amp-dependent synthetase and ligase ABUW_2451 ENOG4105R8C Transcriptional regulator ABUW_2452 ENOG4105C1G acyl-Coa dehydrogenase ABUW_2453 ENOG4107QX3 carboxylase ABUW_2454 ENOG4105E39 Enoyl-CoA hydratase ABUW_2457 ENOG4105CC0 LysR family Transcriptional regulator ABUW_2460 ENOG4105CSU acyl-Coa dehydrogenase ABUW_2462 ENOG4105EQ0 Major Facilitator superfamily ABUW_2464 ENOG4107QNJ CoA-transferase subunit B ABUW_2465 ENOG4107QP7 CoA-transferase subunit A ABUW_2466 ENOG4107RGD Major Facilitator superfamily ABUW_2467 ENOG4105C1G acyl-Coa dehydrogenase ABUW_2468 ENOG4105E39 Enoyl-CoA hydratase ABUW_2469 ENOG4105CHR reductase ABUW_2470 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ABUW_2471 ENOG4105CHU acetyl-coa acetyltransferase ABUW_2473 ENOG4105EQ0 Major Facilitator superfamily ABUW_2474 ENOG4105EA8 2-Nitropropane dioxygenase ABUW_2475 ENOG4108UKI Enoyl-CoA hydratase ABUW_2477 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F ABUW_2478 ENOG4105C1G acyl-Coa dehydrogenase ABUW_2479 ENOG4107RGD Major Facilitator superfamily ABUW_2480 ENOG4108KAZ Involved in phosphonate degradation (By similarity) ABUW_2481 ENOG4107STF Involved in phosphonate degradation (By similarity) ABUW_2483 ENOG4107RCV ABC transporter, permease ABUW_2484 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ABUW_2485 ENOG4105C4Y ABC transporter ABUW_2487 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase ABUW_2488 ENOG4107HP6 Transcriptional regulator ABUW_2490 ENOG4105HEI LysR family (Transcriptional regulator ABUW_2491 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase ABUW_2492 ENOG4105C26 Dehydrogenase ABUW_2494 ENOG4105ETS cytosine purines uracil thiamine allantoin ABUW_2496 ENOG4105C26 Dehydrogenase ABUW_2497 ENOG4108M8W Monooxygenase ABUW_2498 ENOG4105MXW flavin reductase domain protein, FMN-binding ABUW_2499 ENOG4108MXF Alpha Beta Hydrolase ABUW_2503 ENOG4105CPW cytochrome b561 ABUW_2504 ENOG4107VGR Catalase ABUW_2505 ENOG4105CSP Major Facilitator Superfamily ABUW_2506 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase ABUW_2507 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F ABUW_2513 ENOG4105VEQ Cold shock protein ABUW_2521 ENOG4105C4R Atp-dependent dna helicase ABUW_2522 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) ABUW_2523 ENOG4107YAU phenylacetic acid degradation protein ABUW_2524 ENOG4108Z0R Transferase ABUW_2525 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein ABUW_2526 ENOG4105DZS Phenylacetate-CoA ligase ABUW_2527 ENOG4105CHU acetyl-coa acetyltransferase ABUW_2528 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ABUW_2529 ENOG4108UKI Enoyl-CoA hydratase ABUW_2530 ENOG4105E39 Enoyl-CoA hydratase ABUW_2531 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ABUW_2532 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit ABUW_2533 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit ABUW_2534 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit ABUW_2535 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit ABUW_2536 ENOG4105DXM phenylacetic acid degradation protein ABUW_2537 ENOG4105EJQ L-serine dehydratase ABUW_2541 ENOG4107QTZ amino acid ABUW_2542 ENOG4105CZJ Aldehyde dehydrogenase ABUW_2547 ENOG4105MWK D-amino acid dehydrogenase, small subunit ABUW_2551 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABUW_2555 ENOG4108Z4X TRANSCRIPTIONal ABUW_2557 ENOG4105WPN DNA integration recombination invertion protein ABUW_2560 ENOG4105DJ2 Major Facilitator Superfamily ABUW_2561 ENOG4107Y2X deaminase ABUW_2563 ENOG4105EMY transcriptional regulator ABUW_2569 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ABUW_2571 ENOG4105UYK outer membrane protein a ABUW_2585 ENOG4108HW3 (ABC) transporter ABUW_2587 ENOG4105MRR Transcriptional regulator (By similarity) ABUW_2590 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF ABUW_2591 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ABUW_2594 ENOG4105E2A Dehydrogenase ABUW_2596 ENOG4105R8C Transcriptional regulator ABUW_2602 ENOG4107R4J Chloride channel ABUW_2603 ENOG4108JIK carboxylase ABUW_2607 ENOG4105C5A transporter ABUW_2609 ENOG4108WAV Transcriptional regulator ABUW_2613 ENOG4105CNA YD repeat protein ABUW_2617 ENOG4105CNA YD repeat protein ABUW_2623 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) ABUW_2628 ENOG4105D2S major facilitator superfamily ABUW_2630 ENOG4105D1S lipid A biosynthesis ABUW_2632 ENOG4107AQZ Membrane ABUW_2636 ENOG4108Z4U Ferredoxin ABUW_2644 ENOG4105DFG type I secretion outer membrane protein ABUW_2645 ENOG4108IUZ ABC transporter ABUW_2646 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA ABUW_2648 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase ABUW_2649 ENOG4105C2X Arabinose 5-phosphate isomerase ABUW_2664 ENOG41090AG Bacteriophage protein ABUW_2668 ENOG4107ZQ5 Phage-associated protein, HI1409 family ABUW_2682 ENOG4107YPT transcriptional regulator ABUW_2688 ENOG4105II7 pyrroline-5-carboxylate reductase ABUW_2690 ENOG4105VEQ Cold shock protein ABUW_2691 ENOG410829K Lysine exporter protein (Lyse ygga) ABUW_2698 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) ABUW_2709 ENOG4108KB2 LysR family Transcriptional regulator ABUW_2710 ENOG4105FUY alpha subunit ABUW_2711 ENOG4108UKV benzoate 1,2-dioxygenase ABUW_2712 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein ABUW_2713 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase ABUW_2714 ENOG4105DKK Benzoate ABUW_2715 ENOG4105D2S major facilitator superfamily ABUW_2718 ENOG4105CQ7 ATP-dependent helicase ABUW_2719 ENOG4105D3R alkyl hydroperoxide reductase ABUW_2721 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) ABUW_2723 ENOG4108JU3 Alkyl hydroperoxide reductase ABUW_2725 ENOG4108K3A Glutathione S-transferase ABUW_2727 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) ABUW_2728 ENOG4108TGY Glutathione S-transferase ABUW_2730 ENOG4108ZG0 Ompa motb domain protein ABUW_2731 ENOG4105CD3 dihydroorotase ABUW_2737 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ABUW_2740 ENOG4108UKZ OsmC family ABUW_2741 ENOG4107RYR Transcriptional regulator, Crp Fnr family ABUW_2742 ENOG4105CPC Aldo Keto reductase ABUW_2745 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis ABUW_2747 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ABUW_2749 ENOG4105CFH Aspartokinase ABUW_2751 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) ABUW_2753 ENOG4105CPW cytochrome b561 ABUW_2754 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) ABUW_2755 ENOG4105C7N Xanthine uracil vitamin C permease ABUW_2757 ENOG4105F95 Monooxygenase ABUW_2764 ENOG4105F95 Monooxygenase ABUW_2765 ENOG4105JQZ Methyltransferase ABUW_2767 ENOG4107RN6 Monooxygenase ABUW_2771 ENOG4105EPF Outer membrane porin ABUW_2772 ENOG4105D2S major facilitator superfamily ABUW_2774 ENOG4105E3J oxidoreductase ABUW_2777 ENOG4108SC4 )-transporter ABUW_2778 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase ABUW_2781 ENOG4105C1G acyl-Coa dehydrogenase ABUW_2782 ENOG4105EPF Outer membrane porin ABUW_2783 ENOG4105NI3 Protein of unknown function (DUF3237) ABUW_2786 ENOG4105JXH GntR family transcriptional regulator ABUW_2787 ENOG4105CZJ Aldehyde dehydrogenase ABUW_2789 ENOG4105EQX glucarate dehydratase ABUW_2790 ENOG4105DJB Major Facilitator Superfamily ABUW_2791 ENOG4105CTX dehydratase ABUW_2792 ENOG4105DJP Membrane ABUW_2793 ENOG4108ZX5 transcriptional regulator ABUW_2794 ENOG4107RGH Aldehyde dehydrogenase ABUW_2798 ENOG4105C85 amino acid ABUW_2802 ENOG4105C26 Dehydrogenase ABUW_2806 ENOG4105CUB amino acid ABUW_2808 ENOG4105C85 amino acid ABUW_2816 ENOG4105CNA YD repeat protein ABUW_2820 ENOG4105D01 (LipO)protein ABUW_2822 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABUW_2826 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) ABUW_2836 ENOG4108JQ5 ABC transporter ABUW_2837 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component ABUW_2838 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component ABUW_2840 ENOG4105E9H Lytic Murein transglycosylase ABUW_2840 ENOG4105E9H Lytic Murein transglycosylase ABUW_2841 ENOG4107RZZ dna polymerase iii epsilon subunit ABUW_2843 ENOG4105E09 nadh pyrophosphatase ABUW_2845 ENOG4105W4M Transport-associated protein ABUW_2847 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) ABUW_2849 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) ABUW_2850 ENOG4108ZUB Lysine exporter protein (Lyse ygga) ABUW_2854 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family ABUW_2855 ENOG4105D0A hydroxylase ABUW_2856 ENOG4107RAQ aminopeptidase ABUW_2863 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase ABUW_2867 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b ABUW_2869 ENOG4105D82 Glutamate dehydrogenase ABUW_2870 ENOG4108R3D Electron transport complex ABUW_2871 ENOG4105CSM endonuclease III ABUW_2876 ENOG4105CJN penicillin-binding protein ABUW_2877 ENOG4106H78 methyltransferase ABUW_2880 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) ABUW_2882 ENOG4105CQM Urea amidohydrolase subunit alpha ABUW_2888 ENOG4107RET Isocitrate lyase ABUW_2890 ENOG4105C37 (CBS) domain ABUW_2892 ENOG4105D4T Citrate transporter ABUW_2895 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) ABUW_2898 ENOG4108MRJ ABUW_2902 ENOG4105VCQ rubredoxin ABUW_2903 ENOG4107QZF nitrite reductase NADPH large subunit ABUW_2905 ENOG4105C5Q Transcriptional regulator ABUW_2909 ENOG4107U91 Rhomboid family ABUW_2910 ENOG4105CV6 ABC transporter, permease ABUW_2911 ENOG4108I0Y (ABC) transporter ABUW_2912 ENOG4108UJV acyl-CoA thioesterase i ABUW_2916 ENOG4107RNH Outer membrane receptor FepA ABUW_2920 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) ABUW_2921 ENOG4105E6M Sulphatase-modifying factor protein ABUW_2925 ENOG4105CJ3 phosphate transporter ABUW_2926 ENOG4105C3R Methionine synthase ABUW_2929 ENOG4105CSP Major Facilitator Superfamily ABUW_2931 ENOG4108PZW LysR family Transcriptional regulator ABUW_2933 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) ABUW_2934 ENOG4105EU0 Major facilitator Superfamily ABUW_2935 ENOG4108R6W Transcriptional regulator, ARAC family ABUW_2936 ENOG4105CSV Glutaminase ABUW_2937 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) ABUW_2939 ENOG4105CSH Transporter ABUW_2941 ENOG4105C7K acetolactate synthase ABUW_2944 ENOG4105CHR reductase ABUW_2945 ENOG4108MXF Alpha Beta Hydrolase ABUW_2947 ENOG4105DJB Major Facilitator Superfamily ABUW_2948 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase ABUW_2950 ENOG4105CHR reductase ABUW_2954 ENOG41069M3 Transcriptional regulator ABUW_2957 ENOG4106YT9 Enoyl-CoA hydratase ABUW_2959 ENOG4105CND Glycosyl transferase, family 2 ABUW_2960 ENOG4107BJW polysaccharide deacetylase ABUW_2962 ENOG4108VWS Yaeq family ABUW_2964 ENOG4105CKI cobalamin synthesis protein ABUW_2968 ENOG4105C94 Transporter ABUW_2969 ENOG4105C94 Transporter ABUW_2970 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) ABUW_2975 ENOG4107QK5 Homocysteine s-methyltransferase ABUW_2976 ENOG4105D5Q Arginine ornithine antiporter ABUW_2981 ENOG4108YNN Heme oxygenase ABUW_2987 ENOG4108SF5 RNA Polymerase ABUW_2989 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABUW_2990 ENOG4105C54 Major Facilitator superfamily ABUW_2998 ENOG4107QMH DNA methylase ABUW_3005 ENOG4107R3N Filamentation induced by cAMP protein fic ABUW_3007 ENOG4108UUM single-stranded DNA-binding protein ABUW_3017 ENOG4105DFP Integrase ABUW_3018 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ABUW_3019 ENOG4105C0R drug resistance transporter emrb qaca subfamily ABUW_3020 ENOG4105CW7 secretion protein, HlyD family ABUW_3021 ENOG4108VUY thioesterase Superfamily protein ABUW_3022 ENOG4105D52 delta-aminolevulinic acid dehydratase ABUW_3023 ENOG4105MWK D-amino acid dehydrogenase, small subunit ABUW_3024 ENOG4105ECP epimerase ABUW_3028 ENOG4107RH8 nuclease SbcCD subunit D ABUW_3029 ENOG4105EYH Exonuclease ABUW_3030 ENOG4105DFA alanine racemase domain protein ABUW_3031 ENOG4105CZX twitching motility protein ABUW_3032 ENOG4105CZX twitching motility protein ABUW_3033 ENOG41090R7 Ferric uptake ABUW_3038 ENOG4105E7A Glutamine amidotransferase ABUW_3041 ENOG4107QKV phosphomannomutase ABUW_3043 ENOG4105C4R Atp-dependent dna helicase ABUW_3045 ENOG4108ZG0 Ompa motb domain protein ABUW_3046 ENOG4106HNH Acyl-transferase ABUW_3049 ENOG4107QMS site-determining protein ABUW_3053 ENOG4105CNU cell division protein FtsK ABUW_3054 ENOG4105C3M thioredoxin reductase ABUW_3055 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) ABUW_3057 ENOG4105KEG ribosomal-protein-alanine acetyltransferase ABUW_3066 ENOG4108YXA Membrane ABUW_3067 ENOG4105EUB pirin domain protein ABUW_3069 ENOG4105C4K Nad synthetase ABUW_3072 ENOG4105E3J oxidoreductase ABUW_3073 ENOG4105C26 Dehydrogenase ABUW_3074 ENOG4105DVW rieske (2Fe-2S) ABUW_3076 ENOG4105C94 Transporter ABUW_3077 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ABUW_3078 ENOG4105EJC lysr family transcriptional regulator ABUW_3081 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding ABUW_3085 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase ABUW_3086 ENOG4105C34 Pseudouridine synthase ABUW_3087 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ABUW_3088 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) ABUW_3091 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) ABUW_3097 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ABUW_3103 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) ABUW_3105 ENOG4105DWF phosphomethylpyrimidine kinase ABUW_3106 ENOG4109066 lysm domain bon superfamily protein ABUW_3108 ENOG4105CHR reductase ABUW_3109 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ABUW_3111 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein ABUW_3112 ENOG4108BPE -transporting atpase ABUW_3113 ENOG4107RTD sua5 ycio yrdc ywlc family protein ABUW_3114 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) ABUW_3115 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) ABUW_3116 ENOG4105FE9 pseudouridine synthase ABUW_3118 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ABUW_3119 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ABUW_3121 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ABUW_3122 ENOG4108K4C ec 3.1.3.12 ABUW_3123 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase ABUW_3124 ENOG4106UW1 Major Facilitator superfamily ABUW_3129 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) ABUW_3131 ENOG4105HF0 Membrane ABUW_3134 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ABUW_3136 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) ABUW_3146 ENOG4105D1F ATP-binding protein ABUW_3148 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) ABUW_3154 ENOG4105K6H D-cysteine desulfhydrase ABUW_3155 ENOG4105CBX hi0933 family ABUW_3160 ENOG4105DP0 ferredoxin-NADP reductase ABUW_3161 ENOG4105DUM transcriptional regulator, lysR family ABUW_3166 ENOG4105C8S subunit m ABUW_3167 ENOG4105D65 subunit l ABUW_3169 ENOG4107UFS subunit j ABUW_3172 ENOG4108IEH NADH dehydrogenase subunit g ABUW_3173 ENOG4107QIZ NADH dehydrogenase ABUW_3174 ENOG4105GKE subunit e ABUW_3178 ENOG4105BZU Histidine kinase ABUW_3180 ENOG4105E0F Histidine kinase ABUW_3181 ENOG4107EXC regulatoR ABUW_3183 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ABUW_3185 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ABUW_3188 ENOG4105JAB phenazine biosynthesis protein, phzf family ABUW_3194 ENOG41082JN Transcriptional regulator ABUW_3196 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) ABUW_3197 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) ABUW_3199 ENOG4105ETT transcriptional Regulator, LysR family ABUW_3204 ENOG4105CH2 amidohydrolase ABUW_3206 ENOG4106P55 Transcriptional regulator ABUW_3209 ENOG4106P55 Transcriptional regulator ABUW_3210 ENOG4107EFR Flavocytochrome c ABUW_3212 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F ABUW_3213 ENOG4107RGD Major Facilitator superfamily ABUW_3214 ENOG4105C1G acyl-Coa dehydrogenase ABUW_3215 ENOG4105ETT transcriptional Regulator, LysR family ABUW_3222 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) ABUW_3223 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) ABUW_3224 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ABUW_3227 ENOG4105VR0 copper resistance ABUW_3228 ENOG4105E3B Multicopper oxidase ABUW_3230 ENOG4108HCJ Hydrolase ABUW_3231 ENOG4105DJV ribulose-phosphate 3-epimerase ABUW_3233 ENOG4105C4W S-formylglutathione hydrolase ABUW_3236 ENOG41072GX Peptidase M22 Glycoprotease ABUW_3237 ENOG4108Z0R Transferase ABUW_3246 ENOG4105CRQ synthase (Component I) ABUW_3248 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) ABUW_3249 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) ABUW_3250 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) ABUW_3264 ENOG4105K56 Transcriptional regulator ABUW_3265 ENOG4108ZHJ Organic hydroperoxide resistance protein ABUW_3266 ENOG4107QHF type ii secretion system protein e ABUW_3270 ENOG4105C2M dna polymerase I ABUW_3271 ENOG4108VIA integral membrane protein ABUW_3272 ENOG4105II7 pyrroline-5-carboxylate reductase ABUW_3273 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) ABUW_3275 ENOG4105C9X ppx gppa phosphatase ABUW_3277 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) ABUW_3280 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) ABUW_3284 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) ABUW_3287 ENOG4105W39 Membrane ABUW_3288 ENOG4105CYM Glutathione S-transferase ABUW_3291 ENOG4105CEY Amp-dependent synthetase and ligase ABUW_3292 ENOG4105N42 UPF0307 protein ABUW_3293 ENOG41080Z8 PHOSPHOCARRIER protein ABUW_3297 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ABUW_3298 ENOG4105DJ0 Poly(A) Polymerase ABUW_3299 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein ABUW_3300 ENOG4105DXN mazG family ABUW_3302 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ABUW_3305 ENOG4105C6T cysteine synthase ABUW_3306 ENOG4105BZU Histidine kinase ABUW_3307 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase ABUW_3308 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ABUW_3309 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) ABUW_3312 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) ABUW_3313 ENOG4105W8H transhydrogenase (subunit alpha ABUW_3314 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) ABUW_3315 ENOG4106UX7 integral membrane protein ABUW_3321 ENOG4105E3B Multicopper oxidase ABUW_3324 ENOG4105GR3 Histidine kinase ABUW_3342 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ABUW_3344 ENOG4107RSM transcriptional regulator ABUW_3345 ENOG4105CUZ uba thif-type nad fad binding protein ABUW_3346 ENOG4107QM5 aconitate hydratase ABUW_3347 ENOG4105F8V Hydrolase, tatD family ABUW_3350 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) ABUW_3354 ENOG4105BZU Histidine kinase ABUW_3356 ENOG4108ZP8 Acetolactate synthase small subunit ABUW_3357 ENOG4105C7K acetolactate synthase ABUW_3362 ENOG4105DJY efflux transporter, rnd family, mfp subunit ABUW_3363 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) ABUW_3364 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ABUW_3365 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH ABUW_3367 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) ABUW_3368 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) ABUW_3370 ENOG4105VW4 glutaredoxin 3 ABUW_3374 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) ABUW_3378 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) ABUW_3382 ENOG4105WVQ Fe-S assembly protein IscX ABUW_3385 ENOG4105CN1 protease ABUW_3388 ENOG4106HB6 Alpha beta hydrolase ABUW_3390 ENOG4105C26 Dehydrogenase ABUW_3391 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family ABUW_3392 ENOG4105C6Z Gluconate ABUW_3393 ENOG4108UHU Aldolase ABUW_3394 ENOG4105C01 Dihydroxy-acid dehydratase ABUW_3395 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) ABUW_3396 ENOG4108DNC Involved in acetate metabolism (By similarity) ABUW_3397 ENOG4107GFK fumarate ABUW_3401 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) ABUW_3403 ENOG4108ESX Receptor ABUW_3405 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) ABUW_3407 ENOG4105DWV Homoserine O-trans-acetylase ABUW_3427 ENOG4105CIY formyltetrahydrofolate deformylase ABUW_3429 ENOG4107RGH Aldehyde dehydrogenase ABUW_3430 ENOG4105KDC 50s ribosomal protein l28 ABUW_3431 ENOG4105W0E 50S ribosomal protein L33 ABUW_3432 ENOG4105CKD glutathione-regulated potassium-efflux system protein ABUW_3436 ENOG4105VFU Rna-binding protein ABUW_3437 ENOG4105C4R Atp-dependent dna helicase ABUW_3440 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) ABUW_3442 ENOG4105KVH Transcriptional regulator ABUW_3444 ENOG41069P5 Protein slyX homolog ABUW_3445 ENOG4105C5H ABC transporter ABUW_3446 ENOG4105N14 lysine exporter protein LysE YggA ABUW_3447 ENOG4105D1S lipid A biosynthesis ABUW_3449 ENOG4105CK2 sodium dicarboxylate symporter ABUW_3460 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ABUW_3465 ENOG4105DUM transcriptional regulator, lysR family ABUW_3468 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase ABUW_3471 ENOG4108W5M transcriptional regulator ABUW_3474 ENOG4105D29 Helix-turn-helix type 11 domain protein ABUW_3475 ENOG4107XGZ Hydrolase ABUW_3476 ENOG4105EI2 Pseudouridine synthase ABUW_3478 ENOG4105C03 ribonuclease ABUW_3482 ENOG4105CBN LysR family transcriptional regulator ABUW_3483 ENOG4105EMU Dehydrogenase ABUW_3484 ENOG4105CSA Coproporphyrinogen iii oxidase ABUW_3486 ENOG4107QI1 Mate efflux family protein ABUW_3488 ENOG4107T8P acyl-Coa dehydrogenase ABUW_3494 ENOG4105BZ8 glutamate synthase ABUW_3496 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) ABUW_3497 ENOG4105C5X domain protein ABUW_3500 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) ABUW_3502 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase ABUW_3504 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) ABUW_3505 ENOG4108JU5 Magnesium and cobalt efflux protein ABUW_3506 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) ABUW_3507 ENOG4108Z7R Chaperone CsaA ABUW_3509 ENOG4108VAU general secretion pathway protein G ABUW_3510 ENOG4105D7Q type ii secretion system ABUW_3511 ENOG4105C25 Primosomal protein n' ABUW_3512 ENOG4105CKD glutathione-regulated potassium-efflux system protein ABUW_3515 ENOG4105DVC DnaJ domain protein ABUW_3516 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) ABUW_3517 ENOG4107QUT magnesium and cobalt transport protein CorA ABUW_3521 ENOG4107QYX exodeoxyribonuclease v alpha ABUW_3522 ENOG4107QKA exodeoxyribonuclease V beta ABUW_3523 ENOG4105DSY exodeoxyribonuclease V, gamma ABUW_3525 ENOG4105CSR polyphosphate kinase 2 ABUW_3527 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) ABUW_3530 ENOG41061H0 Monooxygenase ABUW_3531 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase ABUW_3534 ENOG4105D65 subunit l ABUW_3535 ENOG4108ZE9 Monovalent cation H antiporter subunit C ABUW_3536 ENOG4107R4Z monovalent cation h antiporter subunit d ABUW_3537 ENOG4105SC1 monovalent cation H antiporter subunit E ABUW_3538 ENOG4105W4C monovalent cation H antiporter subunit F ABUW_3539 ENOG4105KJM monovalent cation h antiporter subunit g ABUW_3542 ENOG4105CHV Transcription elongation factor NusA ABUW_3547 ENOG4107EJC Preprotein translocase subunit SecG ABUW_3549 ENOG4107QHF type ii secretion system protein e ABUW_3552 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) ABUW_3554 ENOG4105C2N RNA methyltransferase TrmH family group 3 ABUW_3557 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) ABUW_3559 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) ABUW_3565 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ABUW_3566 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase ABUW_3578 ENOG4107ZXU DSBA oxidoreductase ABUW_3581 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) ABUW_3584 ENOG4105D3Y Na H antiporter ABUW_3595 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) ABUW_3596 ENOG4105PM1 preprotein translocase subunit SecE ABUW_3604 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) ABUW_3605 ENOG4105TV9 FHA Domain-Containing protein ABUW_3606 ENOG4105GVR general secretion pathway protein D ABUW_3609 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS ABUW_3614 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) ABUW_3615 ENOG4108NEV two component transcriptional regulator, LytTR family ABUW_3616 ENOG4108HRK Histidine kinase ABUW_3619 ENOG4108UTW Plays a role in the regulation of phosphate uptake ABUW_3620 ENOG4105DFG type I secretion outer membrane protein ABUW_3621 ENOG4108RNG Permease of the drug metabolite transporter ABUW_3626 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) ABUW_3627 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters ABUW_3628 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) ABUW_3629 ENOG4105CNI cell division protein FtsW ABUW_3632 ENOG4105CE1 Ferrous iron transport protein b ABUW_3634 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABUW_3635 ENOG4105T95 Thiol disulfide interChange protein ABUW_3636 ENOG4105D6E homoserine dehydrogenase ABUW_3638 ENOG41061WM D-Alanyl-D-Alanine ABUW_3640 ENOG4107TUY Histidine kinase ABUW_3641 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ABUW_3642 ENOG4105CN1 protease ABUW_3643 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) ABUW_3644 ENOG4108K5H permease YjgP YjgQ family protein ABUW_3652 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) ABUW_3654 ENOG4105BZU Histidine kinase ABUW_3659 ENOG4105CHH sulfate transporter ABUW_3665 ENOG4105W1Y Transcriptional regulator ABUW_3668 ENOG41082YX Transcriptional regulator, arsr family ABUW_3670 ENOG4105D6J arsenicaL-resistance protein ABUW_3671 ENOG4105CAU Arsenical resistance protein, ArsH ABUW_3672 ENOG4105C3M thioredoxin reductase ABUW_3673 ENOG4105H3G oxidoreductase ABUW_3680 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABUW_3682 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABUW_3685 ENOG4105EPF Outer membrane porin ABUW_3686 ENOG4105F0N pyrophosphate phospho-hydrolase ABUW_3689 ENOG4105CEY Amp-dependent synthetase and ligase ABUW_3690 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABUW_3691 ENOG41079KZ Major Facilitator Superfamily ABUW_3692 ENOG4105EN6 Membrane ABUW_3693 ENOG4105K5B UPF0225 protein ABUW_3694 ENOG4105EE5 Membrane protein terC ABUW_3696 ENOG4108URH decarboxylase ABUW_3697 ENOG4105C0R drug resistance transporter emrb qaca subfamily ABUW_3699 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABUW_3703 ENOG4105CCT upf0313 protein ABUW_3707 ENOG4105CS1 NAD(P)H quinone oxidoreductase ABUW_3709 ENOG4105C6T cysteine synthase ABUW_3716 ENOG4105Y7M Transcriptional regulator, TetR family ABUW_3723 ENOG4105C79 DNA protecting protein DprA ABUW_3726 ENOG4108IND Tetr family transcriptional regulator ABUW_3727 ENOG4107RTG Major Facilitator superfamily ABUW_3729 ENOG4108V06 Glutathione peroxidase ABUW_3737 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) ABUW_3742 ENOG4105FDK ABC transporter ABUW_3743 ENOG4105FAV ABC, transporter ABUW_3745 ENOG4105EZR dyp-type peroxidase family protein ABUW_3746 ENOG4107R1I NAD-dependent malic enzyme ABUW_3751 ENOG4105EUB pirin domain protein ABUW_3755 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) ABUW_3756 ENOG4106MP8 UPF0754 membrane protein ABUW_3757 ENOG4108VBZ doxx family ABUW_3758 ENOG4105DQR SNARE associated Golgi ABUW_3761 ENOG4107QJE Chromosome Partitioning Protein ABUW_3763 ENOG4107PSF BolA-like protein ABUW_3767 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) ABUW_3772 ENOG4105C1G acyl-Coa dehydrogenase ABUW_3777 ENOG4105CSH Transporter ABUW_3778 ENOG4105E39 Enoyl-CoA hydratase ABUW_3779 ENOG4105E39 Enoyl-CoA hydratase ABUW_3780 ENOG4105C1G acyl-Coa dehydrogenase ABUW_3782 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ABUW_3783 ENOG4105C26 Dehydrogenase ABUW_3785 ENOG4105C85 amino acid ABUW_3786 ENOG4105C85 amino acid ABUW_3787 ENOG4105M4H endoribonuclease L-psp ABUW_3790 ENOG4105EW9 transcriptional regulator AsnC family ABUW_3800 ENOG4105D5G Transposase ABUW_3806 ENOG4108I0Z Aconitate hydratase ABUW_3807 ENOG4105BZN citrate synthase ABUW_3808 ENOG4105CR4 methylisocitrate lyase ABUW_3809 ENOG4105DRR Transcriptional regulator, GntR family ABUW_3810 ENOG4105CGF Aromatic amino acid aminotransferase ABUW_3811 ENOG4105CXG d-lactate dehydrogenase ABUW_3813 ENOG41073TP transcriptional regulator ABUW_3814 ENOG4105DAA L-lactate ABUW_3815 ENOG4107QKV phosphomannomutase ABUW_3816 ENOG4105CMR udp-glucose 4-epimerase ABUW_3818 ENOG4105C6Y Udp-glucose 6-dehydrogenase ABUW_3819 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ABUW_3821 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase ABUW_3822 ENOG4107WZ3 Transferase ABUW_3823 ENOG4105D3Q Sugar transferase ABUW_3828 ENOG4108IJ1 Dehydrogenase ABUW_3829 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ABUW_3830 ENOG4107QQG Dehydrogenase ABUW_3831 ENOG4105DAY polysaccharide export protein ABUW_3833 ENOG4105D75 Capsular exopolysaccharide family ABUW_3834 ENOG4108V1T peptidylprolyl cis-trans isomerase ABUW_3835 ENOG4108V1T peptidylprolyl cis-trans isomerase ABUW_3836 ENOG4105CJR Integral membrane protein (MviN ABUW_3837 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase ABUW_3838 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase ABUW_3840 ENOG4105HSS phospholipase C ABUW_3845 ENOG41062JF Transcriptional regulator ABUW_3848 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) ABUW_3849 ENOG4105UBK short-chain dehydrogenase reductase ABUW_3852 ENOG4107QZM n-acetylglutamate synthase ABUW_3853 ENOG4105GVF (ABC) transporter ABUW_3854 ENOG4105GVF (ABC) transporter ABUW_3855 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) ABUW_3856 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ABUW_3857 ENOG4108VM9 ABC, transporter ABUW_3858 ENOG4108R86 Transcriptional regulator ABUW_3859 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) ABUW_3861 ENOG4105DTN riboflavin biosynthesis protein ribF ABUW_3862 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) ABUW_3864 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase ABUW_3872 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) ABUW_3883 ENOG4105CVE Lytic murein transglycosylase ABUW_3885 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit ABUW_3886 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) ABUW_3888 ENOG4105DFU Cell wall formation (By similarity) ABUW_3890 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase ABUW_3891 ENOG4105DU1 integral membrane protein, terc ABUW_3893 ENOG4106032 Glutathionylspermidine synthase ABUW_3895 ENOG4107QUY Guanine deaminase ABUW_3897 ENOG4108UGV hypoxanthine phosphoribosyltransferase ABUW_3899 ENOG4105T95 Thiol disulfide interChange protein ABUW_3900 ENOG4105PGM cation diffusion facilitator family transporter ABUW_3903 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins ABUW_3906 ENOG4105VG0 50S ribosomal protein l34 ABUW_4012 ENOG4105KK6 nuclease ABUW_4013 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS ABUW_4024 ENOG4105FA0 parb-like partition protein ABUW_4028 ENOG4105CDW Resistance protein ABUW_4056 ENOG4108R0M Aminoglycoside ABUW_4069 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) ABUW_4086 ENOG4105F9F transposase ABUW_4089 ENOG4105F9F transposase ABUW_4095 ENOG4105K5T PilT protein ABUW_4102 ENOG4105T95 Thiol disulfide interChange protein ABUW_4118 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABUW_5008 ENOG4105UGU tonB-dependent Receptor