locus-tag	class	description
HTY63_00010	COG0592	DNA-directed DNA polymerase activity
HTY63_00020	COG0187	DNA topoisomerase II activity
HTY63_00030	COG0586	Pfam SNARE associated Golgi protein
HTY63_00035	COG0488	(ABC) transporter
HTY63_00060	COG0596	Alpha beta hydrolase
HTY63_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HTY63_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HTY63_00110	COG0733	neurotransmitter:sodium symporter activity
HTY63_00150	COG2233	PERMEase
HTY63_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTY63_00200	COG2814	Major facilitator Superfamily
HTY63_00205	COG0656	L-ascorbic acid biosynthetic process
HTY63_00210	COG0583	DNA-binding transcription factor activity
HTY63_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTY63_00230	COG1064	alcohol dehydrogenase
HTY63_00235	COG2818	Glycosylase
HTY63_00250	COG1194	a g-specific adenine glycosylase
HTY63_00270	COG2983	Belongs to the UPF0260 family
HTY63_00275	COG2133	pyrroloquinoline quinone binding
HTY63_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HTY63_00285	COG2116	formate transmembrane transporter activity
HTY63_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HTY63_00310	COG1335	isochorismatase
HTY63_00315	COG0385	Bile acid
HTY63_00320	COG0534	Mate efflux family protein
HTY63_00325	COG1683	Conserved Protein
HTY63_00345	COG0625	glutathione transferase activity
HTY63_00355	COG1113	amino acid transport
HTY63_00365	COG0523	cobalamin synthesis protein
HTY63_00375	COG2188	Transcriptional regulator
HTY63_00405	COG0010	Belongs to the arginase family
HTY63_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HTY63_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HTY63_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HTY63_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HTY63_00540	COG0534	Mate efflux family protein
HTY63_00545	COG0436	Aminotransferase
HTY63_00550	COG2733	membrane
HTY63_00565	COG2918	glutathione biosynthetic process
HTY63_00580	COG1388	LysM domain
HTY63_00580	COG0791	NLP P60 protein
HTY63_00595	COG3150	esterase
HTY63_00605	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HTY63_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTY63_00630	COG2233	PERMEase
HTY63_00635	COG2351	hydroxyisourate hydrolase activity
HTY63_00670	COG3706	GGDEF domain
HTY63_00685	COG1393	Belongs to the ArsC family
HTY63_00690	COG0708	Exodeoxyribonuclease III
HTY63_00710	COG0189	ligase activity
HTY63_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HTY63_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HTY63_00755	COG4942	peptidase
HTY63_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
HTY63_00775	COG2119	membrane
HTY63_00780	COG4774	siderophore transport
HTY63_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTY63_00785	COG0426	domain, Protein
HTY63_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HTY63_00830	COG1902	pentaerythritol trinitrate reductase activity
HTY63_00835	COG1519	Transferase
HTY63_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HTY63_00845	COG0668	transmembrane transport
HTY63_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HTY63_00860	COG1335	isochorismatase
HTY63_00865	COG1522	sequence-specific DNA binding
HTY63_00870	COG3328	transposase activity
HTY63_00895	COG0784	Response regulator, receiver
HTY63_00895	COG2198	Histidine kinase
HTY63_00895	COG2205	protein histidine kinase activity
HTY63_00900	COG3162	membrane
HTY63_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HTY63_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTY63_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HTY63_00940	COG1309	transcriptional regulator
HTY63_00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HTY63_00965	COG0352	thiamine-phosphate diphosphorylase activity
HTY63_00965	COG0351	phosphomethylpyrimidine kinase
HTY63_00975	COG2814	Major facilitator Superfamily
HTY63_00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HTY63_01000	COG1113	amino acid transport
HTY63_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HTY63_01015	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_01025	COG1335	isochorismatase
HTY63_01055	COG2814	Major facilitator Superfamily
HTY63_01060	COG0583	DNA-binding transcription factor activity
HTY63_01080	COG0667	Aldo Keto reductase
HTY63_01110	COG1733	regulation of RNA biosynthetic process
HTY63_01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTY63_01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HTY63_01195	COG2329	Antibiotic biosynthesis monooxygenase
HTY63_01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HTY63_01255	COG0427	acetyl-CoA hydrolase
HTY63_01280	COG0659	secondary active sulfate transmembrane transporter activity
HTY63_01285	COG4221	oxidoreductase activity
HTY63_01290	COG2873	o-acetylhomoserine
HTY63_01295	COG0488	(ABC) transporter
HTY63_01380	COG0833	amino acid
HTY63_01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HTY63_01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HTY63_01445	COG2226	methyltransferase
HTY63_01495	COG0067	glutamate synthase
HTY63_01495	COG0069	glutamate synthase activity
HTY63_01495	COG0070	glutamate synthase
HTY63_01500	COG0493	'glutamate synthase
HTY63_01510	COG1704	LemA family
HTY63_01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HTY63_01535	COG3307	-O-antigen
HTY63_01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HTY63_01575	COG0194	GDP metabolic process
HTY63_01625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HTY63_01645	COG5380	lipid catabolic process
HTY63_01650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HTY63_01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HTY63_01680	COG0277	FAD linked oxidase domain protein
HTY63_01690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HTY63_01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTY63_01710	COG1289	transmembrane transporter activity
HTY63_01720	COG0628	permease
HTY63_01725	COG1192	Involved in chromosome partitioning
HTY63_01755	COG0833	amino acid
HTY63_01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HTY63_01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HTY63_01775	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_01815	COG0583	DNA-binding transcription factor activity
HTY63_01860	COG0517	IMP dehydrogenase activity
HTY63_01865	COG1983	PspC domain protein
HTY63_01875	COG1960	acyl-CoA dehydrogenase activity
HTY63_01890	COG0408	coproporphyrinogen oxidase activity
HTY63_01910	COG0513	Belongs to the DEAD box helicase family
HTY63_01920	COG1127	ABC transporter
HTY63_01925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HTY63_01935	COG2854	intermembrane phospholipid transfer
HTY63_01945	COG0598	Magnesium transport protein CorA
HTY63_01955	COG0494	nUDIX hydrolase
HTY63_01960	COG1040	competence protein
HTY63_01965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HTY63_01985	COG1946	Acyl-CoA thioesterase
HTY63_01990	COG1301	dicarboxylic acid transport
HTY63_02005	COG1959	2 iron, 2 sulfur cluster binding
HTY63_02010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTY63_02010	COG1017	nitric oxide dioxygenase activity
HTY63_02015	COG0433	COG0433 Predicted ATPase
HTY63_02020	COG0626	cystathionine gamma-synthase activity
HTY63_02175	COG1960	acyl-CoA dehydrogenase activity
HTY63_02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HTY63_02210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HTY63_02215	COG0339	signal peptide processing
HTY63_02220	COG0557	exoribonuclease II activity
HTY63_02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
HTY63_02270	COG2169	Transcriptional regulator
HTY63_02275	COG0697	spore germination
HTY63_02280	COG1295	ribonuclease BN
HTY63_02315	COG1702	phosphate starvation-inducible protein PhoH
HTY63_02325	COG0741	lytic transglycosylase activity
HTY63_02325	COG1196	nuclear chromosome segregation
HTY63_02325	COG0739	heme binding
HTY63_02355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HTY63_02360	COG1183	phosphatidylcholine synthase activity
HTY63_02405	COG1960	acyl-CoA dehydrogenase activity
HTY63_02410	COG1309	transcriptional regulator
HTY63_02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HTY63_02430	COG1960	acyl-CoA dehydrogenase activity
HTY63_02450	COG2969	positive regulation of protein catabolic process
HTY63_02460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HTY63_02475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HTY63_02480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HTY63_02500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HTY63_02510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HTY63_02515	COG1408	metallophosphoesterase
HTY63_02525	COG2199	diguanylate cyclase activity
HTY63_02585	COG1607	acyl-coa hydrolase
HTY63_02615	COG2350	Protein conserved in bacteria
HTY63_02625	COG0613	PHP domain protein
HTY63_02630	COG3781	membrane
HTY63_02640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HTY63_02645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HTY63_02655	COG1862	Preprotein translocase
HTY63_02685	COG2205	protein histidine kinase activity
HTY63_02690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HTY63_02710	COG0726	polysaccharide deacetylase
HTY63_02715	COG0463	Glycosyl transferase, family 2
HTY63_02720	COG0438	transferase activity, transferring glycosyl groups
HTY63_02785	COG0625	glutathione transferase activity
HTY63_02790	COG0583	DNA-binding transcription factor activity
HTY63_02795	COG1960	acyl-CoA dehydrogenase activity
HTY63_02800	COG1960	acyl-CoA dehydrogenase activity
HTY63_02810	COG2205	protein histidine kinase activity
HTY63_02815	COG0745	RESPONSE REGULATOR receiver
HTY63_02820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HTY63_02840	COG2096	Adenosyltransferase
HTY63_02890	COG0285	dihydrofolate synthase activity
HTY63_02910	COG0450	alkyl hydroperoxide reductase
HTY63_02925	COG0477	Major facilitator Superfamily
HTY63_02930	COG1272	protein, Hemolysin III
HTY63_02960	COG0183	Belongs to the thiolase family
HTY63_02965	COG2207	Transcriptional regulator
HTY63_02985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTY63_03005	COG0183	Belongs to the thiolase family
HTY63_03015	COG2885	chlorophyll binding
HTY63_03015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HTY63_03025	COG1690	Belongs to the RtcB family
HTY63_03030	COG0833	amino acid
HTY63_03040	COG2233	PERMEase
HTY63_03045	COG1217	gtp-binding protein TYPA
HTY63_03070	COG2094	Belongs to the DNA glycosylase MPG family
HTY63_03075	COG4772	TonB-dependent receptor
HTY63_03090	COG1902	pentaerythritol trinitrate reductase activity
HTY63_03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HTY63_03110	COG0354	folic acid binding
HTY63_03120	COG3189	MarR family transcriptional regulator
HTY63_03125	COG2824	Alkylphosphonate utilization operon protein PhnA
HTY63_03130	COG3422	double-strand break repair
HTY63_03170	COG0840	transmembrane signaling receptor activity
HTY63_03190	COG5510	response to toxic substance
HTY63_03200	COG2832	Protein of unknown function (DUF454)
HTY63_03205	COG1376	ErfK ybiS ycfS ynhG family protein
HTY63_03245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HTY63_03255	COG1289	transmembrane transporter activity
HTY63_03260	COG2814	Major facilitator Superfamily
HTY63_03280	COG1115	amino acid carrier protein
HTY63_03285	COG1752	Esterase of the alpha-beta hydrolase superfamily
HTY63_03290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HTY63_03295	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HTY63_03325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HTY63_03335	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HTY63_03340	COG1077	Cell shape determining protein MreB Mrl
HTY63_03345	COG1792	Involved in formation and maintenance of cell shape
HTY63_03350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HTY63_03355	COG0424	maF-like protein
HTY63_03360	COG1530	ribonuclease E activity
HTY63_03370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HTY63_03380	COG0560	Phosphoserine phosphatase
HTY63_03390	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTY63_03415	COG2207	Transcriptional regulator
HTY63_03435	COG1113	amino acid transport
HTY63_03440	COG2828	Protein conserved in bacteria
HTY63_03445	COG0142	geranyltranstransferase activity
HTY63_03450	COG2315	Protein conserved in bacteria
HTY63_03465	COG1752	Esterase of the alpha-beta hydrolase superfamily
HTY63_03485	COG2194	sulfuric ester hydrolase activity
HTY63_03490	COG0745	RESPONSE REGULATOR receiver
HTY63_03495	COG0642	Histidine kinase
HTY63_03505	COG0004	ammonium transporteR
HTY63_03510	COG0583	DNA-binding transcription factor activity
HTY63_03530	COG0525	valine-tRNA ligase activity
HTY63_03540	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_03550	COG0393	Putative heavy-metal-binding
HTY63_03555	COG0393	Putative heavy-metal-binding
HTY63_03560	COG1538	Outer membrane efflux protein
HTY63_03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTY63_03575	COG0671	phosphoesterase, PA-phosphatase related
HTY63_03605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HTY63_03620	COG1648	precorrin-2 dehydrogenase activity
HTY63_03620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HTY63_03625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HTY63_03630	COG1733	regulation of RNA biosynthetic process
HTY63_03640	COG0531	amino acid
HTY63_03655	COG0321	lipoyl(octanoyl) transferase activity
HTY63_03660	COG2921	Belongs to the UPF0250 family
HTY63_03700	COG2009	succinate dehydrogenase
HTY63_03705	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HTY63_03710	COG1053	succinate dehydrogenase
HTY63_03715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HTY63_03740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HTY63_03760	COG2354	Protein conserved in bacteria
HTY63_03765	COG2321	neutral zinc metallopeptidase
HTY63_03800	COG2843	Capsule synthesis protein
HTY63_03815	COG0589	response to stress
HTY63_03835	COG0505	Belongs to the CarA family
HTY63_03860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HTY63_03865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HTY63_03915	COG0477	Major facilitator Superfamily
HTY63_03920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HTY63_03935	COG1597	lipid kinase activity
HTY63_03940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HTY63_03970	COG0584	glycerophosphoryl diester phosphodiesterase
HTY63_03990	COG0741	lytic transglycosylase activity
HTY63_04010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HTY63_04025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HTY63_04050	COG0778	Nitroreductase
HTY63_04065	COG1929	Belongs to the glycerate kinase type-1 family
HTY63_04070	COG0243	molybdopterin cofactor binding
HTY63_04075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HTY63_04080	COG3339	Conserved Protein
HTY63_04090	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HTY63_04105	COG1113	amino acid transport
HTY63_04115	COG0019	diaminopimelate decarboxylase activity
HTY63_04125	COG1280	lysine exporter protein (LysE YggA)
HTY63_04130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HTY63_04160	COG0463	Glycosyl transferase, family 2
HTY63_04180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTY63_04215	COG4591	ABC-type transport system involved in lipoprotein release permease component
HTY63_04220	COG1136	(ABC) transporter
HTY63_04225	COG2333	competence protein COMEC
HTY63_04225	COG0658	competence protein
HTY63_04235	COG0616	signal peptide processing
HTY63_04235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HTY63_04240	COG0596	Alpha beta hydrolase
HTY63_04245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HTY63_04255	COG0628	permease
HTY63_04290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HTY63_04310	COG0823	Involved in the tonB-independent uptake of proteins
HTY63_04330	COG0824	Thioesterase
HTY63_04335	COG1473	amidohydrolase
HTY63_04355	COG0047	phosphoribosylformylglycinamidine synthase activity
HTY63_04355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HTY63_04360	COG2814	Major facilitator Superfamily
HTY63_04370	COG1024	Enoyl-CoA hydratase
HTY63_04375	COG1051	belongs to the nudix hydrolase family
HTY63_04375	COG1056	cytidyltransferase-related domain
HTY63_04385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTY63_04400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HTY63_04415	COG4625	pathogenesis
HTY63_04420	COG0583	DNA-binding transcription factor activity
HTY63_04425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HTY63_04430	COG4208	sulfate ABC transporter
HTY63_04435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HTY63_04445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HTY63_04450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HTY63_04455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HTY63_04475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HTY63_04490	COG0681	Belongs to the peptidase S26 family
HTY63_04505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HTY63_04515	COG1381	Involved in DNA repair and RecF pathway recombination
HTY63_04520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HTY63_04530	COG4221	oxidoreductase activity
HTY63_04560	COG0436	Aminotransferase
HTY63_04580	COG0556	nucleotide-excision repair
HTY63_04635	COG2070	2-Nitropropane dioxygenase
HTY63_04665	COG1215	transferase activity, transferring glycosyl groups
HTY63_04680	COG0415	Belongs to the DNA photolyase family
HTY63_04690	COG1252	NADH dehydrogenase
HTY63_04695	COG1686	Belongs to the peptidase S11 family
HTY63_04710	COG1187	pseudouridine synthase activity
HTY63_04735	COG0477	Major facilitator Superfamily
HTY63_04740	COG0583	DNA-binding transcription factor activity
HTY63_04745	COG1823	symporter activity
HTY63_04755	COG0612	Peptidase, M16
HTY63_04780	COG0352	thiamine-phosphate diphosphorylase activity
HTY63_04815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTY63_04830	COG1309	transcriptional regulator
HTY63_04840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HTY63_04845	COG0076	glutamate decarboxylase activity
HTY63_04855	COG1522	sequence-specific DNA binding
HTY63_04860	COG3961	Belongs to the TPP enzyme family
HTY63_04865	COG1113	amino acid transport
HTY63_04870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HTY63_04875	COG0573	inorganic phosphate transmembrane transporter activity
HTY63_04885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HTY63_04890	COG0616	signal peptide processing
HTY63_04925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HTY63_04930	COG1686	Belongs to the peptidase S11 family
HTY63_04955	COG0583	DNA-binding transcription factor activity
HTY63_04960	COG1067	ATP-dependent peptidase activity
HTY63_05005	COG1966	Carbon starvation protein
HTY63_05010	COG2879	small protein
HTY63_05040	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HTY63_05040	COG2508	Transcriptional regulator
HTY63_05060	COG1113	amino acid transport
HTY63_05065	COG0583	DNA-binding transcription factor activity
HTY63_05070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTY63_05075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTY63_05085	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_05090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTY63_05095	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HTY63_05095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HTY63_05130	COG2814	Major facilitator Superfamily
HTY63_05135	COG4948	Mandelate Racemase Muconate Lactonizing
HTY63_05145	COG1309	transcriptional regulator
HTY63_05165	COG1741	Belongs to the pirin family
HTY63_05175	COG2964	Protein conserved in bacteria
HTY63_05190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HTY63_05195	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTY63_05200	COG4605	iron ion homeostasis
HTY63_05205	COG4604	ABC transporter, ATP-binding protein
HTY63_05210	COG4607	ABC-type enterochelin transport system periplasmic component
HTY63_05215	COG4774	siderophore transport
HTY63_05225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HTY63_05230	COG1021	2,3-dihydroxybenzoate-AMP ligase
HTY63_05235	COG1535	isochorismatase
HTY63_05235	COG3433	isochorismatase activity
HTY63_05250	COG1132	(ABC) transporter
HTY63_05255	COG1132	(ABC) transporter
HTY63_05260	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HTY63_05270	COG1169	isochorismate synthase
HTY63_05285	COG3739	integral membrane protein
HTY63_05310	COG0302	gtp cyclohydrolase
HTY63_05320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HTY63_05350	COG0308	aminopeptidase N
HTY63_05355	COG0512	Glutamine amidotransferase of anthranilate synthase
HTY63_05370	COG0174	glutamine synthetase
HTY63_05380	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HTY63_05415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HTY63_05420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HTY63_05425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HTY63_05445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HTY63_05450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HTY63_05455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HTY63_05470	COG1960	acyl-CoA dehydrogenase activity
HTY63_05475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HTY63_05480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HTY63_05490	COG2223	nitrite transmembrane transporter activity
HTY63_05500	COG0024	Methionine aminopeptidase
HTY63_05505	COG0052	Belongs to the universal ribosomal protein uS2 family
HTY63_05520	COG2207	Transcriptional regulator
HTY63_05545	COG2951	lytic endotransglycosylase activity
HTY63_05550	COG0772	Belongs to the SEDS family
HTY63_05565	COG0842	Transport permease protein
HTY63_05570	COG1131	(ABC) transporter
HTY63_05615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTY63_05630	COG4215	(ABC) transporter
HTY63_05635	COG4160	amino acid transport
HTY63_05640	COG4598	ABC transporter
HTY63_05650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HTY63_05655	COG0826	peptidase U32
HTY63_05660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTY63_05675	COG1720	tRNA m6t6A37 methyltransferase activity
HTY63_05685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HTY63_05700	COG0642	Histidine kinase
HTY63_05710	COG0494	nUDIX hydrolase
HTY63_05720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HTY63_05725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HTY63_05730	COG3139	Protein of unknown function (DUF1315)
HTY63_05735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HTY63_05740	COG1301	dicarboxylic acid transport
HTY63_05745	COG1960	acyl-CoA dehydrogenase activity
HTY63_05750	COG2819	hydrolase of the alpha beta superfamily
HTY63_05760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HTY63_05770	COG2195	Cleaves the N-terminal amino acid of tripeptides
HTY63_05775	COG1234	tRNA 3'-trailer cleavage
HTY63_05805	COG2363	Small membrane protein
HTY63_05825	COG0513	Belongs to the DEAD box helicase family
HTY63_05835	COG0778	Nitroreductase
HTY63_06190	COG1286	toxin biosynthetic process
HTY63_06215	COG4783	chaperone-mediated protein folding
HTY63_06220	COG1610	YqeY-like protein
HTY63_06320	COG3111	PFAM Bacterial OB fold (BOF) protein
HTY63_06345	COG3243	poly(R)-hydroxyalkanoic acid synthase
HTY63_06350	COG0786	glutamate:sodium symporter activity
HTY63_06360	COG2186	Transcriptional regulator
HTY63_06410	COG0477	Major facilitator Superfamily
HTY63_06495	COG0482	sulfurtransferase activity
HTY63_06510	COG0488	(ABC) transporter
HTY63_06515	COG3173	Aminoglycoside phosphotransferase
HTY63_06525	COG2433	Pfam Transposase IS66
HTY63_06555	COG1301	dicarboxylic acid transport
HTY63_06565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTY63_06570	COG2011	ABC-type metal ion transport system permease component
HTY63_06575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HTY63_06580	COG1464	Belongs to the NlpA lipoprotein family
HTY63_06585	COG0151	Belongs to the GarS family
HTY63_06590	COG0138	bifunctional purine biosynthesis protein purh
HTY63_06595	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HTY63_06625	COG2308	Evidence 4 Homologs of previously reported genes of
HTY63_06635	COG1305	Transglutaminase-like
HTY63_06645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HTY63_06650	COG0305	Participates in initiation and elongation during chromosome replication
HTY63_06675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HTY63_06685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HTY63_06690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HTY63_06715	COG0726	polysaccharide deacetylase
HTY63_06715	COG1649	PFAM Uncharacterised BCR, COG1649
HTY63_06720	COG1215	transferase activity, transferring glycosyl groups
HTY63_06725	COG3658	cytochrome
HTY63_06735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTY63_06750	COG0583	DNA-binding transcription factor activity
HTY63_06770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HTY63_06775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HTY63_06790	COG1960	acyl-CoA dehydrogenase activity
HTY63_06795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HTY63_06800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTY63_06825	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HTY63_06830	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HTY63_06840	COG2205	protein histidine kinase activity
HTY63_06845	COG0745	RESPONSE REGULATOR receiver
HTY63_06850	COG0174	glutamine synthetase
HTY63_06870	COG0729	surface antigen
HTY63_06895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HTY63_06900	COG2814	Major facilitator Superfamily
HTY63_06975	COG3409	Peptidoglycan-binding domain 1 protein
HTY63_06975	COG3267	Type II secretory pathway component ExeA
HTY63_07005	COG0681	Belongs to the peptidase S26 family
HTY63_07040	COG4373	Mu-like prophage FluMu protein gp28
HTY63_07055	COG4383	Mu-like prophage protein gp29
HTY63_07060	COG2369	cell adhesion
HTY63_07065	COG5005	Phage virion morphogenesis
HTY63_07080	COG4397	Mu-like prophage major head subunit gpT
HTY63_07175	COG0583	DNA-binding transcription factor activity
HTY63_07190	COG1187	pseudouridine synthase activity
HTY63_07210	COG0802	atpase or kinase
HTY63_07215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HTY63_07225	COG1923	regulation of RNA biosynthetic process
HTY63_07230	COG0697	spore germination
HTY63_07245	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HTY63_07255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HTY63_07260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HTY63_07260	COG0519	Catalyzes the synthesis of GMP from XMP
HTY63_07265	COG4302	ethanolamine ammonia-lyase activity
HTY63_07270	COG4303	Ethanolamine ammonia lyase large subunit
HTY63_07275	COG0531	amino acid
HTY63_07295	COG1454	alcohol dehydrogenase
HTY63_07300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HTY63_07310	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HTY63_07330	COG0308	aminopeptidase N
HTY63_07340	COG4221	oxidoreductase activity
HTY63_07350	COG1605	Chorismate mutase
HTY63_07365	COG1309	transcriptional regulator
HTY63_07375	COG0668	transmembrane transport
HTY63_07410	COG4773	Receptor
HTY63_07430	COG0488	(ABC) transporter
HTY63_07435	COG0589	response to stress
HTY63_07460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HTY63_07470	COG3135	benzoate transporter
HTY63_07475	COG1522	sequence-specific DNA binding
HTY63_07485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HTY63_07490	COG0583	DNA-binding transcription factor activity
HTY63_07500	COG0183	Belongs to the thiolase family
HTY63_07510	COG2030	dehydratase
HTY63_07515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HTY63_07530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HTY63_07540	COG0824	Thioesterase
HTY63_07545	COG1454	alcohol dehydrogenase
HTY63_07555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HTY63_07575	COG0069	glutamate synthase activity
HTY63_07750	COG5410	chromosome segregation
HTY63_07895	COG1196	nuclear chromosome segregation
HTY63_07895	COG0741	lytic transglycosylase activity
HTY63_07895	COG0739	heme binding
HTY63_07965	COG2814	Major facilitator Superfamily
HTY63_07980	COG0511	ligase activity, forming carbon-carbon bonds
HTY63_08000	COG1116	anion transmembrane transporter activity
HTY63_08000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HTY63_08005	COG0745	RESPONSE REGULATOR receiver
HTY63_08015	COG2146	nitrite reductase [NAD(P)H] activity
HTY63_08015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTY63_08020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTY63_08025	COG0243	molybdopterin cofactor binding
HTY63_08035	COG0243	molybdopterin cofactor binding
HTY63_08040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HTY63_08055	COG0521	Mo-molybdopterin cofactor biosynthetic process
HTY63_08055	COG0315	cyclic pyranopterin monophosphate synthase activity
HTY63_08060	COG0303	'Molybdopterin
HTY63_08070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTY63_08075	COG0697	spore germination
HTY63_08095	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HTY63_08100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HTY63_08165	COG2204	response regulator
HTY63_08170	COG3852	Histidine kinase
HTY63_08190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HTY63_08195	COG0575	Belongs to the CDS family
HTY63_08230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HTY63_08245	COG2137	regulation of response to DNA damage stimulus
HTY63_08255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HTY63_08260	COG1011	Hydrolase
HTY63_08285	COG1522	sequence-specific DNA binding
HTY63_08295	COG1113	amino acid transport
HTY63_08310	COG0659	secondary active sulfate transmembrane transporter activity
HTY63_08315	COG2135	peptidase activity
HTY63_08330	COG3300	MHYT domain
HTY63_08330	COG5001	Diguanylate cyclase
HTY63_08350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HTY63_08350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HTY63_08350	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HTY63_08355	COG1105	Belongs to the carbohydrate kinase PfkB family
HTY63_08360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HTY63_08360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HTY63_08390	COG0024	Methionine aminopeptidase
HTY63_08395	COG0583	DNA-binding transcription factor activity
HTY63_08405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HTY63_08410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HTY63_08415	COG0517	IMP dehydrogenase activity
HTY63_08415	COG0516	GMP reductase activity
HTY63_08440	COG0552	protein localization to endoplasmic reticulum
HTY63_08450	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HTY63_08465	COG4890	Cyd operon protein YbgT
HTY63_08470	COG1294	oxidase, subunit
HTY63_08485	COG1585	Membrane protein implicated in regulation of membrane protease activity
HTY63_08495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HTY63_08500	COG4774	siderophore transport
HTY63_08515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HTY63_08520	COG0569	domain protein
HTY63_08525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HTY63_08555	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HTY63_08560	COG0542	response to heat
HTY63_08585	COG0446	pyridine nucleotide-disulphide oxidoreductase
HTY63_08585	COG1902	pentaerythritol trinitrate reductase activity
HTY63_08630	COG2323	membrane
HTY63_08635	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HTY63_08645	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HTY63_08650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HTY63_08655	COG0183	Belongs to the thiolase family
HTY63_08660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HTY63_08665	COG0596	Alpha beta hydrolase
HTY63_08670	COG2271	Major facilitator Superfamily
HTY63_08675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HTY63_08680	COG3485	protocatechuate 3,4-dioxygenase
HTY63_08685	COG3485	protocatechuate 3,4-dioxygenase
HTY63_08690	COG0710	3-dehydroquinate dehydratase activity
HTY63_08695	COG3420	alginic acid biosynthetic process
HTY63_08700	COG3659	wide pore channel activity
HTY63_08705	COG4993	Dehydrogenase
HTY63_08715	COG2391	methyltransferase activity
HTY63_08730	COG1414	Transcriptional regulator
HTY63_08735	COG0583	DNA-binding transcription factor activity
HTY63_08740	COG1960	acyl-CoA dehydrogenase activity
HTY63_08765	COG2814	Major facilitator Superfamily
HTY63_08775	COG0154	amidase activity
HTY63_08795	COG4638	Rieske (2fe-2S)
HTY63_08805	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_08815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTY63_08825	COG3733	amine oxidase
HTY63_08835	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_08845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HTY63_08850	COG0183	Belongs to the thiolase family
HTY63_08855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HTY63_08860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HTY63_08870	COG4829	muconolactone delta-isomerase
HTY63_08875	COG4948	Mandelate Racemase Muconate Lactonizing
HTY63_08880	COG0583	DNA-binding transcription factor activity
HTY63_08890	COG2186	Transcriptional regulator
HTY63_08910	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_08930	COG1960	acyl-CoA dehydrogenase activity
HTY63_08935	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_08960	COG3162	membrane
HTY63_08975	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_08990	COG0753	catalase activity
HTY63_09010	COG1846	Transcriptional regulator
HTY63_09015	COG1902	pentaerythritol trinitrate reductase activity
HTY63_09015	COG0446	pyridine nucleotide-disulphide oxidoreductase
HTY63_09025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HTY63_09055	COG1309	transcriptional regulator
HTY63_09065	COG1335	isochorismatase
HTY63_09070	COG0583	DNA-binding transcription factor activity
HTY63_09080	COG0475	glutathione-regulated potassium exporter activity
HTY63_09080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HTY63_09090	COG1473	amidohydrolase
HTY63_09100	COG2831	hemolysin activation secretion protein
HTY63_09105	COG3210	domain, Protein
HTY63_09135	COG2188	Transcriptional regulator
HTY63_09150	COG0583	DNA-binding transcription factor activity
HTY63_09180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HTY63_09200	COG1566	PFAM secretion protein HlyD family protein
HTY63_09215	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_09220	COG0129	dihydroxy-acid dehydratase activity
HTY63_09230	COG0583	DNA-binding transcription factor activity
HTY63_09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HTY63_09245	COG2084	Dehydrogenase
HTY63_09250	COG2207	Transcriptional regulator
HTY63_09265	COG1064	alcohol dehydrogenase
HTY63_09275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTY63_09280	COG1120	ATPase activity
HTY63_09300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HTY63_09415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HTY63_09445	COG3539	Fimbrial protein
HTY63_09475	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HTY63_09485	COG0753	catalase activity
HTY63_09500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HTY63_09565	COG3433	isochorismatase activity
HTY63_09565	COG1535	isochorismatase
HTY63_09570	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_09575	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HTY63_09580	COG4149	molybdate abc transporter
HTY63_09585	COG0725	ABC transporter, periplasmic molybdate-binding protein
HTY63_09595	COG4638	Rieske (2fe-2S)
HTY63_09600	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HTY63_09605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTY63_09605	COG0543	2 iron, 2 sulfur cluster binding
HTY63_09630	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_09645	COG2207	Transcriptional regulator
HTY63_09655	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_09660	COG2610	gluconate transmembrane transporter activity
HTY63_09670	COG0583	DNA-binding transcription factor activity
HTY63_09680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HTY63_09685	COG2031	fatty acid transporter
HTY63_09690	COG0183	Belongs to the thiolase family
HTY63_09695	COG0583	DNA-binding transcription factor activity
HTY63_09700	COG0583	DNA-binding transcription factor activity
HTY63_09715	COG1027	Aspartate ammonia-lyase
HTY63_09725	COG0477	Major facilitator Superfamily
HTY63_09745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HTY63_09750	COG4521	taurine ABC transporter
HTY63_09765	COG2188	Transcriptional regulator
HTY63_09775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HTY63_09780	COG1733	regulation of RNA biosynthetic process
HTY63_09785	COG3708	Transcriptional regulator
HTY63_09785	COG2207	Transcriptional regulator
HTY63_09800	COG0730	response to heat
HTY63_09810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTY63_09810	COG3453	Protein conserved in bacteria
HTY63_09820	COG3781	membrane
HTY63_09825	COG1063	alcohol dehydrogenase
HTY63_09835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HTY63_09840	COG0508	dehydrogenase complex catalyzes the overall conversion of
HTY63_09845	COG0022	dehydrogenase e1 component
HTY63_09850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HTY63_09855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HTY63_09870	COG3706	GGDEF domain
HTY63_09885	COG0133	tryptophan synthase activity
HTY63_09895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HTY63_09930	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HTY63_09955	COG2226	methyltransferase
HTY63_10010	COG0842	Transport permease protein
HTY63_10015	COG0842	Transport permease protein
HTY63_10020	COG1131	(ABC) transporter
HTY63_10035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HTY63_10040	COG4773	Receptor
HTY63_10060	COG0730	response to heat
HTY63_10065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HTY63_10085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HTY63_10100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HTY63_10140	COG4264	IucA IucC family
HTY63_10145	COG4264	IucA IucC family
HTY63_10165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HTY63_10180	COG1960	acyl-CoA dehydrogenase activity
HTY63_10185	COG1960	acyl-CoA dehydrogenase activity
HTY63_10190	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HTY63_10195	COG2207	Transcriptional regulator
HTY63_10200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HTY63_10205	COG0776	regulation of translation
HTY63_10230	COG0822	iron-sulfur transferase activity
HTY63_10235	COG0316	Belongs to the HesB IscA family
HTY63_10265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HTY63_10285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HTY63_10290	COG0702	epimerase
HTY63_10325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HTY63_10335	COG0339	signal peptide processing
HTY63_10385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HTY63_10390	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HTY63_10420	COG0776	regulation of translation
HTY63_10485	COG0084	hydrolase, TatD family'
HTY63_10505	COG1663	tetraacyldisaccharide 4'-kinase activity
HTY63_10510	COG1132	(ABC) transporter
HTY63_10520	COG0811	peptide transport
HTY63_10525	COG1475	DNA binding
HTY63_10530	COG1192	Involved in chromosome partitioning
HTY63_10540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HTY63_10555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HTY63_10560	COG0191	fructose-bisphosphate aldolase activity
HTY63_10580	COG0424	maF-like protein
HTY63_10585	COG2850	peptidyl-arginine hydroxylation
HTY63_10595	COG0640	Transcriptional regulator
HTY63_10605	COG3619	membrane
HTY63_10610	COG3122	Protein conserved in bacteria
HTY63_10615	COG1132	(ABC) transporter
HTY63_10635	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HTY63_10640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HTY63_10650	COG0506	proline dehydrogenase activity
HTY63_10650	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HTY63_10650	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HTY63_10655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HTY63_10670	COG3698	Phosphodiester glycosidase
HTY63_10680	COG2353	YceI-like domain
HTY63_10690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HTY63_10735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HTY63_10735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HTY63_10760	COG3539	Fimbrial protein
HTY63_10765	COG3121	Chaperone
HTY63_10790	COG0697	spore germination
HTY63_10800	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HTY63_10810	COG0583	DNA-binding transcription factor activity
HTY63_10830	COG1309	transcriptional regulator
HTY63_10845	COG1522	sequence-specific DNA binding
HTY63_10860	COG1126	abc transporter atp-binding protein
HTY63_10865	COG0765	amino acid transport
HTY63_10870	COG0765	amino acid transport
HTY63_10900	COG1464	Belongs to the NlpA lipoprotein family
HTY63_10920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HTY63_10925	COG2011	ABC-type metal ion transport system permease component
HTY63_10930	COG0012	GTP binding
HTY63_10955	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HTY63_10995	COG0386	Belongs to the glutathione peroxidase family
HTY63_11005	COG0436	Aminotransferase
HTY63_11045	COG3634	alkyl hydroperoxide reductase activity
HTY63_11060	COG0583	DNA-binding transcription factor activity
HTY63_11065	COG0798	PFAM Bile acid sodium symporter
HTY63_11070	COG0640	Transcriptional regulator
HTY63_11085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HTY63_11095	COG0583	DNA-binding transcription factor activity
HTY63_11105	COG1953	Uracil, thiamine, allantoin
HTY63_11115	COG2175	clavaminate synthase activity
HTY63_11120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HTY63_11125	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HTY63_11130	COG4521	taurine ABC transporter
HTY63_11140	COG0477	Major facilitator Superfamily
HTY63_11160	COG1271	oxidase subunit
HTY63_11165	COG1294	oxidase, subunit
HTY63_11175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTY63_11195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HTY63_11215	COG3052	prosthetic group binding
HTY63_11220	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HTY63_11230	COG2814	Major facilitator Superfamily
HTY63_11250	COG1346	cytolysis
HTY63_11260	COG0583	DNA-binding transcription factor activity
HTY63_11265	COG0625	glutathione transferase activity
HTY63_11270	COG0625	glutathione transferase activity
HTY63_11275	COG0583	DNA-binding transcription factor activity
HTY63_11290	COG1045	serine acetyltransferase
HTY63_11295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HTY63_11300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HTY63_11310	COG1280	lysine exporter protein (LysE YggA)
HTY63_11325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HTY63_11330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HTY63_11335	COG1126	abc transporter atp-binding protein
HTY63_11340	COG0765	amino acid transport
HTY63_11345	COG0765	amino acid transport
HTY63_11365	COG0784	Response regulator, receiver
HTY63_11365	COG2205	protein histidine kinase activity
HTY63_11385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HTY63_11405	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_11455	COG0583	DNA-binding transcription factor activity
HTY63_11475	COG0318	PFAM AMP-dependent synthetase and ligase
HTY63_11480	COG1309	transcriptional regulator
HTY63_11485	COG1960	acyl-CoA dehydrogenase activity
HTY63_11490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HTY63_11495	COG1024	Enoyl-CoA hydratase
HTY63_11500	COG4770	biotin carboxylase activity
HTY63_11510	COG0583	DNA-binding transcription factor activity
HTY63_11525	COG1960	acyl-CoA dehydrogenase activity
HTY63_11535	COG2814	Major facilitator Superfamily
HTY63_11545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HTY63_11550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HTY63_11555	COG2814	Major facilitator Superfamily
HTY63_11560	COG1960	acyl-CoA dehydrogenase activity
HTY63_11565	COG1024	Enoyl-CoA hydratase
HTY63_11570	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_11575	COG1250	3-hydroxyacyl-CoA dehydrogenase
HTY63_11580	COG0183	Belongs to the thiolase family
HTY63_11590	COG2814	Major facilitator Superfamily
HTY63_11600	COG1024	Enoyl-CoA hydratase
HTY63_11615	COG1960	acyl-CoA dehydrogenase activity
HTY63_11620	COG2814	Major facilitator Superfamily
HTY63_11625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HTY63_11630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HTY63_11645	COG3842	ATPase activity
HTY63_11650	COG1840	ABC-type Fe3 transport system, periplasmic component
HTY63_11660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTY63_11665	COG1414	Transcriptional regulator
HTY63_11675	COG0583	DNA-binding transcription factor activity
HTY63_11680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HTY63_11685	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_11695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HTY63_11705	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_11710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTY63_11715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTY63_11720	COG2267	carboxylic ester hydrolase activity
HTY63_11740	COG3038	cytochrome b561
HTY63_11745	COG0753	catalase activity
HTY63_11780	COG2050	protein possibly involved in aromatic compounds catabolism
HTY63_11790	COG3327	negative regulation of DNA-templated transcription, initiation
HTY63_11795	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HTY63_11800	COG0183	Belongs to the thiolase family
HTY63_11805	COG1250	3-hydroxyacyl-CoA dehydrogenase
HTY63_11810	COG1024	Enoyl-CoA hydratase
HTY63_11815	COG1024	Enoyl-CoA hydratase
HTY63_11820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTY63_11825	COG2151	metal-sulfur cluster biosynthetic enzyme
HTY63_11830	COG3396	Phenylacetate-CoA oxygenase
HTY63_11835	COG3460	Phenylacetate-CoA oxygenase
HTY63_11840	COG3396	Phenylacetate-CoA oxygenase
HTY63_11845	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_11845	COG2030	dehydratase
HTY63_11850	COG1760	l-serine dehydratase
HTY63_11855	COG0531	amino acid
HTY63_11860	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_11875	COG0446	pyridine nucleotide-disulphide oxidoreductase
HTY63_11885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HTY63_11905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HTY63_11915	COG0789	Transcriptional regulator
HTY63_11930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HTY63_11945	COG2807	transmembrane transport
HTY63_11950	COG0590	tRNA wobble adenosine to inosine editing
HTY63_12065	COG1116	anion transmembrane transporter activity
HTY63_12070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HTY63_12080	COG0864	Transcriptional regulator
HTY63_12100	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTY63_12105	COG0439	Biotin carboxylase
HTY63_12120	COG1063	alcohol dehydrogenase
HTY63_12130	COG1309	transcriptional regulator
HTY63_12150	COG0038	chloride channel
HTY63_12155	COG4770	biotin carboxylase activity
HTY63_12175	COG1914	H( )-stimulated, divalent metal cation uptake system
HTY63_12180	COG0583	DNA-binding transcription factor activity
HTY63_12230	COG1250	3-hydroxyacyl-CoA dehydrogenase
HTY63_12250	COG2814	Major facilitator Superfamily
HTY63_12260	COG1560	Kdo2-lipid A biosynthetic process
HTY63_12270	COG5006	permease, DMT superfamily
HTY63_12275	COG1522	sequence-specific DNA binding
HTY63_12290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HTY63_12300	COG4122	O-methyltransferase activity
HTY63_12330	COG1538	Outer membrane efflux protein
HTY63_12335	COG1137	ATPase activity
HTY63_12340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HTY63_12350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HTY63_12355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HTY63_12355	COG0517	IMP dehydrogenase activity
HTY63_12400	COG2814	Major facilitator Superfamily
HTY63_12435	COG1278	Cold shock
HTY63_12440	COG1280	lysine exporter protein (LysE YggA)
HTY63_12470	COG1570	exodeoxyribonuclease VII activity
HTY63_12520	COG0583	DNA-binding transcription factor activity
HTY63_12525	COG4638	Rieske (2fe-2S)
HTY63_12530	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HTY63_12535	COG0543	2 iron, 2 sulfur cluster binding
HTY63_12535	COG0633	Ferredoxin
HTY63_12540	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_12545	COG3135	benzoate transporter
HTY63_12550	COG2814	Major facilitator Superfamily
HTY63_12565	COG1643	Atp-dependent helicase
HTY63_12570	COG0450	alkyl hydroperoxide reductase
HTY63_12580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HTY63_12590	COG3634	alkyl hydroperoxide reductase activity
HTY63_12610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HTY63_12615	COG0625	glutathione transferase activity
HTY63_12625	COG2885	chlorophyll binding
HTY63_12660	COG0542	response to heat
HTY63_12675	COG1765	OsmC-like protein
HTY63_12690	COG0667	Aldo Keto reductase
HTY63_12705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HTY63_12715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HTY63_12725	COG0527	aspartate kinase activity
HTY63_12735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HTY63_12745	COG3038	cytochrome b561
HTY63_12750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HTY63_12755	COG2252	PERMEase
HTY63_12795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HTY63_12825	COG1113	amino acid transport
HTY63_12845	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_12865	COG0531	amino acid
HTY63_12875	COG1113	amino acid transport
HTY63_12915	COG3209	COG3209 Rhs family protein
HTY63_12945	COG4269	membrane
HTY63_12960	COG0446	pyridine nucleotide-disulphide oxidoreductase
HTY63_12960	COG1902	pentaerythritol trinitrate reductase activity
HTY63_12970	COG2203	Gaf domain
HTY63_12970	COG3706	GGDEF domain
HTY63_12970	COG4251	negative regulation of phosphorylation
HTY63_12970	COG5001	Diguanylate cyclase
HTY63_12980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HTY63_13000	COG4172	Belongs to the ABC transporter superfamily
HTY63_13005	COG4239	(ABC) transporter, permease
HTY63_13010	COG4174	ABC transporter (Permease)
HTY63_13020	COG1388	LysM domain
HTY63_13020	COG0741	lytic transglycosylase activity
HTY63_13020	COG1388	LysM domain
HTY63_13020	COG0741	lytic transglycosylase activity
HTY63_13025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HTY63_13065	COG0583	DNA-binding transcription factor activity
HTY63_13070	COG1279	arginine transmembrane transporter activity
HTY63_13090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTY63_13095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTY63_13100	COG0006	proline dipeptidase activity
HTY63_13185	COG0739	heme binding
HTY63_13185	COG0741	lytic transglycosylase activity
HTY63_13185	COG1196	nuclear chromosome segregation
HTY63_13245	COG4695	Portal protein
HTY63_13340	COG0305	Participates in initiation and elongation during chromosome replication
HTY63_13355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HTY63_13405	COG2194	sulfuric ester hydrolase activity
HTY63_13450	COG0739	heme binding
HTY63_13775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HTY63_13800	COG3384	dioxygenase
HTY63_13810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HTY63_13815	COG2878	Part of a membrane complex involved in electron transport
HTY63_13820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HTY63_13845	COG0768	penicillin binding
HTY63_13850	COG0742	ribosomal rna small subunit methyltransferase
HTY63_13865	COG0830	nickel cation binding
HTY63_13875	COG0804	urea catabolic process
HTY63_13915	COG1253	flavin adenine dinucleotide binding
HTY63_13920	COG2851	Citrate transporter
HTY63_13970	COG1773	rubredoxin
HTY63_13975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTY63_13985	COG0583	DNA-binding transcription factor activity
HTY63_14010	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HTY63_14015	COG4181	ATPase activity
HTY63_14060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HTY63_14080	COG0306	phosphate transporter
HTY63_14090	COG3958	Transketolase
HTY63_14095	COG3959	Transketolase, thiamine diphosphate binding domain
HTY63_14100	COG2271	Major facilitator Superfamily
HTY63_14105	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_14110	COG0583	DNA-binding transcription factor activity
HTY63_14125	COG2223	nitrite transmembrane transporter activity
HTY63_14130	COG2207	Transcriptional regulator
HTY63_14135	COG2066	Belongs to the glutaminase family
HTY63_14140	COG0242	peptide deformylase activity
HTY63_14145	COG0477	Major facilitator Superfamily
HTY63_14155	COG0028	Belongs to the TPP enzyme family
HTY63_14170	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_14175	COG2267	carboxylic ester hydrolase activity
HTY63_14185	COG2271	Major facilitator Superfamily
HTY63_14190	COG0446	pyridine nucleotide-disulphide oxidoreductase
HTY63_14200	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_14220	COG1414	Transcriptional regulator
HTY63_14235	COG1024	Enoyl-CoA hydratase
HTY63_14245	COG1215	transferase activity, transferring glycosyl groups
HTY63_14250	COG1649	PFAM Uncharacterised BCR, COG1649
HTY63_14250	COG0726	polysaccharide deacetylase
HTY63_14260	COG4681	YaeQ
HTY63_14270	COG0523	cobalamin synthesis protein
HTY63_14280	COG1607	acyl-coa hydrolase
HTY63_14290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTY63_14295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTY63_14300	COG1309	transcriptional regulator
HTY63_14325	COG2040	homocysteine
HTY63_14330	COG0531	amino acid
HTY63_14385	COG1595	DNA-templated transcription, initiation
HTY63_14395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HTY63_14400	COG0477	Major facilitator Superfamily
HTY63_14420	COG0084	hydrolase, TatD family'
HTY63_14455	COG0629	single-stranded DNA binding
HTY63_14510	COG0582	viral genome integration into host DNA
HTY63_14535	COG1061	Type III restriction enzyme res subunit
HTY63_14545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HTY63_14550	COG1192	Involved in chromosome partitioning
HTY63_14560	COG1061	Type III restriction enzyme res subunit
HTY63_14650	COG0592	DNA-directed DNA polymerase activity
HTY63_14690	COG2026	Addiction module toxin, RelE StbE family
HTY63_14840	COG3755	Protein conserved in bacteria
HTY63_14885	COG1484	DNA-dependent DNA replication
HTY63_14975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HTY63_15045	COG0405	Gamma-glutamyltransferase
HTY63_15050	COG2814	Major facilitator Superfamily
HTY63_15060	COG2050	protein possibly involved in aromatic compounds catabolism
HTY63_15075	COG1090	epimerase
HTY63_15095	COG0420	3'-5' exonuclease activity
HTY63_15120	COG0735	belongs to the Fur family
HTY63_15125	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HTY63_15145	COG0121	glutamine amidotransferase
HTY63_15160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HTY63_15170	COG0210	DNA helicase
HTY63_15175	COG2885	chlorophyll binding
HTY63_15180	COG0204	Acyl-transferase
HTY63_15195	COG2894	cell division
HTY63_15215	COG1280	lysine exporter protein (LysE YggA)
HTY63_15220	COG1674	ftsk spoiiie
HTY63_15220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HTY63_15225	COG0492	ferredoxin-NADP+ reductase activity
HTY63_15230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HTY63_15240	COG0456	acetyltransferase
HTY63_15285	COG1981	membrane
HTY63_15300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HTY63_15300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HTY63_15320	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_15330	COG0657	acetylesterase activity
HTY63_15340	COG0473	3-isopropylmalate dehydrogenase activity
HTY63_15345	COG0583	DNA-binding transcription factor activity
HTY63_15365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HTY63_15390	COG0564	pseudouridine synthase activity
HTY63_15400	COG0358	DNA primase activity
HTY63_15415	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HTY63_15445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HTY63_15475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HTY63_15485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HTY63_15485	COG0352	thiamine-phosphate diphosphorylase activity
HTY63_15485	COG0351	phosphomethylpyrimidine kinase
HTY63_15490	COG1652	LysM domain
HTY63_15515	COG1399	metal-binding, possibly nucleic acid-binding protein
HTY63_15520	COG3101	peptidyl-lysine hydroxylation
HTY63_15525	COG0009	L-threonylcarbamoyladenylate synthase
HTY63_15530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HTY63_15535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HTY63_15550	COG4106	trans-aconitate 2-methyltransferase activity
HTY63_15565	COG0596	Alpha beta hydrolase
HTY63_15565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HTY63_15565	COG2226	methyltransferase
HTY63_15570	COG1877	trehalose-phosphatase activity
HTY63_15575	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HTY63_15580	COG2223	nitrite transmembrane transporter activity
HTY63_15600	COG1196	nuclear chromosome segregation
HTY63_15610	COG0730	response to heat
HTY63_15625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HTY63_15635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HTY63_15685	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HTY63_15690	COG0489	protein tyrosine kinase activity
HTY63_15700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HTY63_15700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HTY63_15730	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HTY63_15735	COG2081	HI0933 family
HTY63_15745	COG0668	transmembrane transport
HTY63_15765	COG0583	DNA-binding transcription factor activity
HTY63_15785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HTY63_15790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HTY63_15820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HTY63_15860	COG0745	RESPONSE REGULATOR receiver
HTY63_15880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HTY63_15890	COG2205	protein histidine kinase activity
HTY63_15960	COG4993	Dehydrogenase
HTY63_15985	COG0384	phenazine biosynthesis protein PhzF
HTY63_16010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTY63_16025	COG0583	DNA-binding transcription factor activity
HTY63_16055	COG0583	DNA-binding transcription factor activity
HTY63_16070	COG0583	DNA-binding transcription factor activity
HTY63_16075	COG1053	succinate dehydrogenase
HTY63_16085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HTY63_16090	COG2814	Major facilitator Superfamily
HTY63_16095	COG1960	acyl-CoA dehydrogenase activity
HTY63_16100	COG0583	DNA-binding transcription factor activity
HTY63_16105	COG1063	alcohol dehydrogenase
HTY63_16135	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HTY63_16140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HTY63_16145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HTY63_16160	COG3667	copper resistance
HTY63_16165	COG2132	Multicopper oxidase
HTY63_16175	COG0561	phosphatase activity
HTY63_16180	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HTY63_16205	COG1214	PFAM Peptidase M22, glycoprotease
HTY63_16255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HTY63_16265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HTY63_16270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HTY63_16275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HTY63_16335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HTY63_16345	COG1846	Transcriptional regulator
HTY63_16350	COG1764	response to oxidative stress
HTY63_16390	COG0037	tRNA processing
HTY63_16400	COG0248	Ppx GppA phosphatase
HTY63_16430	COG0072	phenylalanine-tRNA ligase activity
HTY63_16470	COG1238	metal cluster binding
HTY63_16475	COG0625	glutathione transferase activity
HTY63_16490	COG0318	PFAM AMP-dependent synthetase and ligase
HTY63_16495	COG3028	Belongs to the UPF0307 family
HTY63_16500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HTY63_16520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HTY63_16525	COG0617	tRNA 3'-terminal CCA addition
HTY63_16530	COG1555	photosystem II stabilization
HTY63_16535	COG3956	TIGRFAM MazG family protein
HTY63_16545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HTY63_16565	COG0784	Response regulator, receiver
HTY63_16565	COG2205	protein histidine kinase activity
HTY63_16565	COG5002	protein histidine kinase activity
HTY63_16570	COG1024	Enoyl-CoA hydratase
HTY63_16575	COG2084	Dehydrogenase
HTY63_16580	COG3622	Belongs to the hyi family
HTY63_16610	COG0697	spore germination
HTY63_16620	COG2814	Major facilitator Superfamily
HTY63_16625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HTY63_16635	COG0583	DNA-binding transcription factor activity
HTY63_16645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HTY63_16660	COG0084	hydrolase, TatD family'
HTY63_16675	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HTY63_16705	COG0440	acetolactate synthase activity
HTY63_16710	COG0028	Belongs to the TPP enzyme family
HTY63_16735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTY63_16740	COG0577	efflux transmembrane transporter activity
HTY63_16740	COG1136	(ABC) transporter
HTY63_16745	COG1538	Outer membrane efflux protein
HTY63_16760	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HTY63_16765	COG1162	GTPase activity
HTY63_16775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HTY63_16795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HTY63_16800	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_16840	COG2986	histidine ammonia-lyase
HTY63_16855	COG0318	PFAM AMP-dependent synthetase and ligase
HTY63_16865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HTY63_16910	COG1426	Protein conserved in bacteria
HTY63_16945	COG0793	Belongs to the peptidase S41A family
HTY63_16960	COG2267	carboxylic ester hydrolase activity
HTY63_16970	COG1012	belongs to the aldehyde dehydrogenase family
HTY63_16975	COG3265	gluconokinase activity
HTY63_16985	COG0800	Aldolase
HTY63_16995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HTY63_17000	COG0857	belongs to the CobB CobQ family
HTY63_17000	COG0280	phosphate acetyltransferase
HTY63_17005	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HTY63_17005	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HTY63_17025	COG0740	serine-type endopeptidase activity
HTY63_17035	COG4774	siderophore transport
HTY63_17045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HTY63_17055	COG2813	Specifically methylates the guanine in position
HTY63_17055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HTY63_17155	COG0788	formyltetrahydrofolate deformylase activity
HTY63_17180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HTY63_17180	COG4651	solute:proton antiporter activity
HTY63_17200	COG0724	RNA recognition motif
HTY63_17205	COG0210	DNA helicase
HTY63_17230	COG1733	regulation of RNA biosynthetic process
HTY63_17240	COG2900	Belongs to the SlyX family
HTY63_17245	COG0488	(ABC) transporter
HTY63_17250	COG1280	lysine exporter protein (LysE YggA)
HTY63_17255	COG1560	Kdo2-lipid A biosynthetic process
HTY63_17265	COG1301	dicarboxylic acid transport
HTY63_17320	COG0473	3-isopropylmalate dehydrogenase activity
HTY63_17385	COG0583	DNA-binding transcription factor activity
HTY63_17395	COG0625	glutathione transferase activity
HTY63_17400	COG2378	regulation of single-species biofilm formation
HTY63_17405	COG0546	phosphoglycolate phosphatase activity
HTY63_17415	COG1530	ribonuclease E activity
HTY63_17420	COG0318	PFAM AMP-dependent synthetase and ligase
HTY63_17435	COG0583	DNA-binding transcription factor activity
HTY63_17440	COG4221	oxidoreductase activity
HTY63_17445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HTY63_17455	COG0534	Mate efflux family protein
HTY63_17470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HTY63_17510	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HTY63_17515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTY63_17530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HTY63_17540	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HTY63_17540	COG0644	oxidoreductase
HTY63_17545	COG0425	Belongs to the sulfur carrier protein TusA family
HTY63_17550	COG4535	Mg2 and Co2 transporter CorC
HTY63_17560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HTY63_17580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HTY63_17585	COG0475	glutathione-regulated potassium exporter activity
HTY63_17585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HTY63_17590	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HTY63_17600	COG0484	heat shock protein binding
HTY63_17605	COG0789	Transcriptional regulator
HTY63_17610	COG0598	Magnesium transport protein CorA
HTY63_17625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HTY63_17630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HTY63_17635	COG1074	ATP-dependent DNA helicase activity
HTY63_17640	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HTY63_17660	COG2226	methyltransferase
HTY63_17675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTY63_17680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HTY63_17695	COG2111	Na H antiporter
HTY63_17695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HTY63_17700	COG1006	Multisubunit Na H antiporter MnhC subunit
HTY63_17705	COG0651	ATP synthesis coupled electron transport
HTY63_17710	COG1863	multisubunit Na H antiporter MnhE subunit
HTY63_17715	COG2212	antiporter activity
HTY63_17720	COG1320	monovalent cation:proton antiporter activity
HTY63_17735	COG0195	Participates in both transcription termination and antitermination
HTY63_17785	COG0237	dephospho-CoA kinase activity
HTY63_17795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HTY63_17810	COG0497	DNA recombination
HTY63_17820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HTY63_17850	COG2169	Transcriptional regulator
HTY63_17850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HTY63_17855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HTY63_17920	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HTY63_17935	COG0326	Molecular chaperone. Has ATPase activity
HTY63_17950	COG2056	Na+-H+ antiporter family
HTY63_17955	COG0596	Alpha beta hydrolase
HTY63_18050	COG0546	phosphoglycolate phosphatase activity
HTY63_18055	COG1716	ATPase activity
HTY63_18100	COG0181	hydroxymethylbilane synthase activity
HTY63_18110	COG3275	phosphorelay sensor kinase activity
HTY63_18130	COG1538	Outer membrane efflux protein
HTY63_18135	COG0697	spore germination
HTY63_18160	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HTY63_18165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HTY63_18170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HTY63_18175	COG0772	Belongs to the SEDS family
HTY63_18200	COG4974	Belongs to the 'phage' integrase family
HTY63_18205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HTY63_18215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HTY63_18225	COG2197	response regulator
HTY63_18240	COG0793	Belongs to the peptidase S41A family
HTY63_18245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HTY63_18250	COG0795	lipopolysaccharide-transporting ATPase activity
HTY63_18290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HTY63_18290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HTY63_18300	COG0004	ammonium transporteR
HTY63_18305	COG0347	Belongs to the P(II) protein family
HTY63_18315	COG0606	chelatase, subunit chli
HTY63_18370	COG0659	secondary active sulfate transmembrane transporter activity
HTY63_18375	COG0589	response to stress
HTY63_18420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HTY63_18465	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HTY63_18495	COG0659	secondary active sulfate transmembrane transporter activity
HTY63_18500	COG0589	response to stress
HTY63_18530	COG0606	chelatase, subunit chli
HTY63_18535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTY63_18545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HTY63_18560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HTY63_18575	COG0318	PFAM AMP-dependent synthetase and ligase
HTY63_18585	COG0477	Major facilitator Superfamily
HTY63_18590	COG2860	membrane
HTY63_18600	COG1253	flavin adenine dinucleotide binding
HTY63_18620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HTY63_18655	COG0655	NAD(P)H dehydrogenase (quinone) activity
HTY63_18665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HTY63_18700	COG1309	transcriptional regulator
HTY63_18735	COG0758	DNA mediated transformation
HTY63_18745	COG0697	spore germination
HTY63_18750	COG1309	transcriptional regulator
HTY63_18765	COG0386	Belongs to the glutathione peroxidase family
HTY63_18830	COG1121	(ABC) transporter
HTY63_18835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HTY63_18840	COG1280	lysine exporter protein (LysE YggA)
HTY63_18845	COG2837	iron assimilation
HTY63_18855	COG0281	malic enzyme
HTY63_18900	COG0519	Catalyzes the synthesis of GMP from XMP
HTY63_18900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HTY63_18905	COG4399	Belongs to the UPF0754 family
HTY63_18910	COG2259	Doxx family
HTY63_18915	COG0586	Pfam SNARE associated Golgi protein
HTY63_18930	COG1192	Involved in chromosome partitioning
HTY63_18940	COG0271	Belongs to the BolA IbaG family
HTY63_18955	COG2267	carboxylic ester hydrolase activity
HTY63_18975	COG3321	synthase
HTY63_18975	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HTY63_18975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HTY63_18975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HTY63_18980	COG1960	acyl-CoA dehydrogenase activity
HTY63_18990	COG2197	response regulator
HTY63_19000	COG3916	Acyl-homoserine-lactone synthase
HTY63_19005	COG0477	Major facilitator Superfamily
HTY63_19010	COG1024	Enoyl-CoA hydratase
HTY63_19015	COG1024	Enoyl-CoA hydratase
HTY63_19020	COG1960	acyl-CoA dehydrogenase activity
HTY63_19025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HTY63_19045	COG1113	amino acid transport
HTY63_19050	COG1113	amino acid transport
HTY63_19055	COG0251	oxidation-reduction process
HTY63_19095	COG0564	pseudouridine synthase activity
HTY63_19155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HTY63_19170	COG1802	Transcriptional regulator
HTY63_19180	COG1448	Aminotransferase
HTY63_19185	COG0277	FAD linked oxidase domain protein
HTY63_19195	COG2186	Transcriptional regulator
HTY63_19205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HTY63_19210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HTY63_19225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HTY63_19230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HTY63_19255	COG2244	polysaccharide biosynthetic process
HTY63_19260	COG1083	cytidylyl-transferase
HTY63_19265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HTY63_19275	COG2089	acid synthase
HTY63_19280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HTY63_19285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HTY63_19295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HTY63_19300	COG1596	polysaccharide export
HTY63_19325	COG0728	peptidoglycan biosynthetic process
HTY63_19330	COG3023	N-Acetylmuramoyl-L-alanine amidase
HTY63_19385	COG0546	phosphoglycolate phosphatase activity
HTY63_19390	COG1028	Short-chain dehydrogenase reductase Sdr
HTY63_19410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HTY63_19415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HTY63_19420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTY63_19425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HTY63_19430	COG1116	anion transmembrane transporter activity
HTY63_19435	COG1309	transcriptional regulator
HTY63_19440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HTY63_19450	COG0196	riboflavin kinase activity
HTY63_19455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HTY63_19465	COG1047	Peptidyl-prolyl cis-trans
HTY63_19505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HTY63_19510	COG0657	acetylesterase activity
HTY63_19560	COG2951	lytic endotransglycosylase activity
HTY63_19565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HTY63_19580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HTY63_19590	COG0671	phosphoesterase, PA-phosphatase related
HTY63_19595	COG0861	Integral membrane protein TerC family
HTY63_19605	COG0754	glutathionylspermidine amidase activity
HTY63_19615	COG0402	S-adenosylhomocysteine deaminase activity
HTY63_19630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HTY63_19635	COG1230	cation diffusion facilitator family transporter
HTY63_19650	COG0706	membrane insertase activity
HTY63_19715	COG4683	PFAM Phage derived protein Gp49-like (DUF891)