locus-tag	class	description
L2Z15_00010	COG0786	glutamate:sodium symporter activity
L2Z15_00015	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z15_00040	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z15_00140	COG1610	YqeY-like protein
L2Z15_00145	COG4783	chaperone-mediated protein folding
L2Z15_00170	COG1286	toxin biosynthetic process
L2Z15_00200	COG0778	Nitroreductase
L2Z15_00210	COG0513	Belongs to the DEAD box helicase family
L2Z15_00240	COG2363	Small membrane protein
L2Z15_00270	COG1234	tRNA 3'-trailer cleavage
L2Z15_00275	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z15_00285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z15_00295	COG2819	hydrolase of the alpha beta superfamily
L2Z15_00300	COG1960	acyl-CoA dehydrogenase activity
L2Z15_00305	COG1301	dicarboxylic acid transport
L2Z15_00310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z15_00315	COG3139	Protein of unknown function (DUF1315)
L2Z15_00320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z15_00325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z15_00335	COG0494	nUDIX hydrolase
L2Z15_00360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z15_00370	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z15_00385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z15_00390	COG0826	peptidase U32
L2Z15_00395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z15_00405	COG4598	ABC transporter
L2Z15_00410	COG4160	amino acid transport
L2Z15_00415	COG4215	(ABC) transporter
L2Z15_00430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z15_00475	COG1131	(ABC) transporter
L2Z15_00480	COG0842	Transport permease protein
L2Z15_00495	COG0772	Belongs to the SEDS family
L2Z15_00500	COG2951	lytic endotransglycosylase activity
L2Z15_00525	COG2207	Transcriptional regulator
L2Z15_00540	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z15_00545	COG0024	Methionine aminopeptidase
L2Z15_00555	COG2223	nitrite transmembrane transporter activity
L2Z15_00565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z15_00570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z15_00575	COG1960	acyl-CoA dehydrogenase activity
L2Z15_00590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z15_00595	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z15_00600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z15_00620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z15_00630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z15_00635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z15_00670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z15_00680	COG0174	glutamine synthetase
L2Z15_00695	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z15_00730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z15_00740	COG0302	gtp cyclohydrolase
L2Z15_00765	COG3739	integral membrane protein
L2Z15_00780	COG1169	isochorismate synthase
L2Z15_00790	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z15_00795	COG1132	(ABC) transporter
L2Z15_00800	COG1132	(ABC) transporter
L2Z15_00815	COG1535	isochorismatase
L2Z15_00815	COG3433	isochorismatase activity
L2Z15_00820	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z15_00825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z15_00835	COG4774	siderophore transport
L2Z15_00840	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z15_00845	COG4604	ABC transporter, ATP-binding protein
L2Z15_00850	COG4605	iron ion homeostasis
L2Z15_00855	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z15_00860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z15_00875	COG2964	Protein conserved in bacteria
L2Z15_00885	COG1741	Belongs to the pirin family
L2Z15_00905	COG1309	transcriptional regulator
L2Z15_00915	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z15_00920	COG2814	Major facilitator Superfamily
L2Z15_00955	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L2Z15_00955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z15_00960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z15_00970	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_00980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z15_00985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z15_00990	COG0583	DNA-binding transcription factor activity
L2Z15_00995	COG1113	amino acid transport
L2Z15_01005	COG4372	Transposase
L2Z15_01035	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z15_01035	COG2508	Transcriptional regulator
L2Z15_01070	COG2879	small protein
L2Z15_01075	COG1966	Carbon starvation protein
L2Z15_01120	COG1067	ATP-dependent peptidase activity
L2Z15_01125	COG0583	DNA-binding transcription factor activity
L2Z15_01150	COG1686	Belongs to the peptidase S11 family
L2Z15_01155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z15_01190	COG0616	signal peptide processing
L2Z15_01195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z15_01205	COG0573	inorganic phosphate transmembrane transporter activity
L2Z15_01210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2Z15_01215	COG1113	amino acid transport
L2Z15_01220	COG3961	Belongs to the TPP enzyme family
L2Z15_01225	COG1522	sequence-specific DNA binding
L2Z15_01235	COG0076	glutamate decarboxylase activity
L2Z15_01240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z15_01250	COG1309	transcriptional regulator
L2Z15_01265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z15_01300	COG0352	thiamine-phosphate diphosphorylase activity
L2Z15_01325	COG0612	Peptidase, M16
L2Z15_01335	COG1823	symporter activity
L2Z15_01340	COG0583	DNA-binding transcription factor activity
L2Z15_01345	COG0477	Major facilitator Superfamily
L2Z15_01365	COG1187	pseudouridine synthase activity
L2Z15_01395	COG1252	NADH dehydrogenase
L2Z15_01405	COG0415	Belongs to the DNA photolyase family
L2Z15_01420	COG1215	transferase activity, transferring glycosyl groups
L2Z15_01450	COG2070	2-Nitropropane dioxygenase
L2Z15_01505	COG0556	nucleotide-excision repair
L2Z15_01525	COG0436	Aminotransferase
L2Z15_01555	COG4221	oxidoreductase activity
L2Z15_01565	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z15_01570	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z15_01580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z15_01595	COG0681	Belongs to the peptidase S26 family
L2Z15_01610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z15_01630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z15_01635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z15_01640	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z15_01650	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z15_01655	COG4208	sulfate ABC transporter
L2Z15_01660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z15_01665	COG0583	DNA-binding transcription factor activity
L2Z15_01670	COG4625	pathogenesis
L2Z15_01685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z15_01700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z15_01710	COG1051	belongs to the nudix hydrolase family
L2Z15_01710	COG1056	cytidyltransferase-related domain
L2Z15_01715	COG1024	Enoyl-CoA hydratase
L2Z15_01725	COG2814	Major facilitator Superfamily
L2Z15_01730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z15_01730	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z15_01750	COG1473	amidohydrolase
L2Z15_01755	COG0824	Thioesterase
L2Z15_01775	COG0823	Involved in the tonB-independent uptake of proteins
L2Z15_01795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z15_01830	COG0628	permease
L2Z15_01840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z15_01845	COG0596	Alpha beta hydrolase
L2Z15_01850	COG0616	signal peptide processing
L2Z15_01850	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z15_01860	COG2333	competence protein COMEC
L2Z15_01860	COG0658	competence protein
L2Z15_01865	COG1136	(ABC) transporter
L2Z15_01870	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z15_01905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z15_01955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z15_01960	COG1280	lysine exporter protein (LysE YggA)
L2Z15_01965	COG2267	carboxylic ester hydrolase activity
L2Z15_01975	COG0019	diaminopimelate decarboxylase activity
L2Z15_01985	COG1113	amino acid transport
L2Z15_02000	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z15_02010	COG3339	Conserved Protein
L2Z15_02015	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z15_02020	COG0243	molybdopterin cofactor binding
L2Z15_02025	COG1929	Belongs to the glycerate kinase type-1 family
L2Z15_02040	COG0778	Nitroreductase
L2Z15_02075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z15_02090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z15_02110	COG0741	lytic transglycosylase activity
L2Z15_02130	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z15_02135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z15_02160	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z15_02165	COG1597	lipid kinase activity
L2Z15_02180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z15_02185	COG0477	Major facilitator Superfamily
L2Z15_02235	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z15_02240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z15_02265	COG0505	Belongs to the CarA family
L2Z15_02285	COG0589	response to stress
L2Z15_02300	COG2843	Capsule synthesis protein
L2Z15_02320	COG2321	neutral zinc metallopeptidase
L2Z15_02325	COG2354	Protein conserved in bacteria
L2Z15_02345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z15_02370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z15_02375	COG1053	succinate dehydrogenase
L2Z15_02380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z15_02385	COG2009	succinate dehydrogenase
L2Z15_02425	COG2921	Belongs to the UPF0250 family
L2Z15_02430	COG0321	lipoyl(octanoyl) transferase activity
L2Z15_02445	COG0531	amino acid
L2Z15_02455	COG1733	regulation of RNA biosynthetic process
L2Z15_02460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z15_02465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z15_02465	COG1648	precorrin-2 dehydrogenase activity
L2Z15_02480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z15_02510	COG0671	phosphoesterase, PA-phosphatase related
L2Z15_02515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z15_02525	COG1538	Outer membrane efflux protein
L2Z15_02530	COG0393	Putative heavy-metal-binding
L2Z15_02535	COG0393	Putative heavy-metal-binding
L2Z15_02545	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_02555	COG0525	valine-tRNA ligase activity
L2Z15_02575	COG0583	DNA-binding transcription factor activity
L2Z15_02580	COG0004	ammonium transporteR
L2Z15_02595	COG0642	Histidine kinase
L2Z15_02600	COG0745	RESPONSE REGULATOR receiver
L2Z15_02610	COG4372	Transposase
L2Z15_02645	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z15_02660	COG2315	Protein conserved in bacteria
L2Z15_02665	COG0142	geranyltranstransferase activity
L2Z15_02670	COG2828	Protein conserved in bacteria
L2Z15_02675	COG1113	amino acid transport
L2Z15_02695	COG2207	Transcriptional regulator
L2Z15_02720	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z15_02730	COG0560	Phosphoserine phosphatase
L2Z15_02740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z15_02750	COG1530	ribonuclease E activity
L2Z15_02755	COG0424	maF-like protein
L2Z15_02760	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z15_02765	COG1792	Involved in formation and maintenance of cell shape
L2Z15_02770	COG1077	Cell shape determining protein MreB Mrl
L2Z15_02775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z15_02785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z15_02810	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z15_02815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z15_02820	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z15_02825	COG1115	amino acid carrier protein
L2Z15_02845	COG2814	Major facilitator Superfamily
L2Z15_02850	COG1289	transmembrane transporter activity
L2Z15_02860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z15_02900	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z15_02905	COG2832	Protein of unknown function (DUF454)
L2Z15_02915	COG5510	response to toxic substance
L2Z15_02945	COG0840	transmembrane signaling receptor activity
L2Z15_02985	COG3422	double-strand break repair
L2Z15_02990	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z15_02995	COG3189	MarR family transcriptional regulator
L2Z15_03005	COG0354	folic acid binding
L2Z15_03010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z15_03020	COG0679	Auxin Efflux Carrier
L2Z15_03025	COG1902	pentaerythritol trinitrate reductase activity
L2Z15_03030	COG4772	TonB-dependent receptor
L2Z15_03035	COG2094	Belongs to the DNA glycosylase MPG family
L2Z15_03060	COG1217	gtp-binding protein TYPA
L2Z15_03065	COG2233	PERMEase
L2Z15_03075	COG0833	amino acid
L2Z15_03080	COG1690	Belongs to the RtcB family
L2Z15_03090	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z15_03090	COG2885	chlorophyll binding
L2Z15_03100	COG0183	Belongs to the thiolase family
L2Z15_03120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z15_03140	COG2207	Transcriptional regulator
L2Z15_03145	COG0183	Belongs to the thiolase family
L2Z15_03165	COG2153	protein acetylation
L2Z15_03175	COG1272	protein, Hemolysin III
L2Z15_03180	COG0477	Major facilitator Superfamily
L2Z15_03195	COG0450	alkyl hydroperoxide reductase
L2Z15_03215	COG0285	dihydrofolate synthase activity
L2Z15_03265	COG2096	Adenosyltransferase
L2Z15_03285	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z15_03290	COG0745	RESPONSE REGULATOR receiver
L2Z15_03295	COG2205	protein histidine kinase activity
L2Z15_03305	COG1960	acyl-CoA dehydrogenase activity
L2Z15_03310	COG1960	acyl-CoA dehydrogenase activity
L2Z15_03360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z15_03375	COG0438	transferase activity, transferring glycosyl groups
L2Z15_03380	COG0463	Glycosyl transferase, family 2
L2Z15_03385	COG0726	polysaccharide deacetylase
L2Z15_03405	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z15_03410	COG2205	protein histidine kinase activity
L2Z15_03560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L2Z15_03570	COG3646	Phage regulatory protein
L2Z15_03615	COG0629	single-stranded DNA binding
L2Z15_03620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z15_03665	COG1862	Preprotein translocase
L2Z15_03680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z15_03690	COG3781	membrane
L2Z15_03695	COG0613	PHP domain protein
L2Z15_03705	COG2350	Protein conserved in bacteria
L2Z15_03735	COG1607	acyl-coa hydrolase
L2Z15_03795	COG2199	diguanylate cyclase activity
L2Z15_03805	COG1408	metallophosphoesterase
L2Z15_03810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z15_03820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z15_03840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z15_03845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z15_03860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z15_03870	COG2969	positive regulation of protein catabolic process
L2Z15_03890	COG1960	acyl-CoA dehydrogenase activity
L2Z15_03895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z15_03910	COG1309	transcriptional regulator
L2Z15_03915	COG1960	acyl-CoA dehydrogenase activity
L2Z15_03960	COG1183	phosphatidylcholine synthase activity
L2Z15_03965	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z15_03995	COG1196	nuclear chromosome segregation
L2Z15_03995	COG0739	heme binding
L2Z15_03995	COG0741	lytic transglycosylase activity
L2Z15_04005	COG1702	phosphate starvation-inducible protein PhoH
L2Z15_04040	COG1295	ribonuclease BN
L2Z15_04045	COG0697	spore germination
L2Z15_04050	COG2169	Transcriptional regulator
L2Z15_04055	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z15_04100	COG0557	exoribonuclease II activity
L2Z15_04105	COG0339	signal peptide processing
L2Z15_04110	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z15_04140	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z15_04145	COG1960	acyl-CoA dehydrogenase activity
L2Z15_04300	COG0626	cystathionine gamma-synthase activity
L2Z15_04305	COG0433	COG0433 Predicted ATPase
L2Z15_04310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z15_04310	COG1017	nitric oxide dioxygenase activity
L2Z15_04315	COG1959	2 iron, 2 sulfur cluster binding
L2Z15_04330	COG1301	dicarboxylic acid transport
L2Z15_04335	COG1946	Acyl-CoA thioesterase
L2Z15_04355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z15_04360	COG1040	competence protein
L2Z15_04365	COG0494	nUDIX hydrolase
L2Z15_04375	COG0598	Magnesium transport protein CorA
L2Z15_04395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z15_04400	COG1127	ABC transporter
L2Z15_04410	COG0513	Belongs to the DEAD box helicase family
L2Z15_04430	COG0408	coproporphyrinogen oxidase activity
L2Z15_04445	COG1960	acyl-CoA dehydrogenase activity
L2Z15_04455	COG1983	PspC domain protein
L2Z15_04460	COG0517	IMP dehydrogenase activity
L2Z15_04510	COG0583	DNA-binding transcription factor activity
L2Z15_04550	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_04560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z15_04565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z15_04570	COG0833	amino acid
L2Z15_04600	COG1192	Involved in chromosome partitioning
L2Z15_04605	COG0628	permease
L2Z15_04615	COG1289	transmembrane transporter activity
L2Z15_04630	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z15_04635	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z15_04645	COG0277	FAD linked oxidase domain protein
L2Z15_04650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z15_04675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z15_04680	COG5380	lipid catabolic process
L2Z15_04700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z15_04750	COG0194	GDP metabolic process
L2Z15_04765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z15_04800	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z15_04805	COG1704	LemA family
L2Z15_04815	COG0493	'glutamate synthase
L2Z15_04820	COG0069	glutamate synthase activity
L2Z15_04820	COG0067	glutamate synthase
L2Z15_04820	COG0070	glutamate synthase
L2Z15_04870	COG2226	methyltransferase
L2Z15_04885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z15_04890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z15_04935	COG0833	amino acid
L2Z15_05000	COG0488	(ABC) transporter
L2Z15_05005	COG2873	o-acetylhomoserine
L2Z15_05010	COG4221	oxidoreductase activity
L2Z15_05015	COG0659	secondary active sulfate transmembrane transporter activity
L2Z15_05040	COG0427	acetyl-CoA hydrolase
L2Z15_05065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z15_05105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z15_05165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2Z15_05175	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z15_05180	COG1733	regulation of RNA biosynthetic process
L2Z15_05195	COG1733	regulation of RNA biosynthetic process
L2Z15_05215	COG0667	Aldo Keto reductase
L2Z15_05235	COG0583	DNA-binding transcription factor activity
L2Z15_05240	COG2814	Major facilitator Superfamily
L2Z15_05270	COG1335	isochorismatase
L2Z15_05280	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_05285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z15_05295	COG1113	amino acid transport
L2Z15_05305	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z15_05320	COG2814	Major facilitator Superfamily
L2Z15_05330	COG0352	thiamine-phosphate diphosphorylase activity
L2Z15_05330	COG0351	phosphomethylpyrimidine kinase
L2Z15_05330	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z15_05350	COG1309	transcriptional regulator
L2Z15_05355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z15_05370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z15_05380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z15_05385	COG3162	membrane
L2Z15_05390	COG0784	Response regulator, receiver
L2Z15_05390	COG2198	Histidine kinase
L2Z15_05390	COG2205	protein histidine kinase activity
L2Z15_05415	COG1522	sequence-specific DNA binding
L2Z15_05420	COG1335	isochorismatase
L2Z15_05425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z15_05435	COG0668	transmembrane transport
L2Z15_05440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z15_05445	COG1519	Transferase
L2Z15_05450	COG1902	pentaerythritol trinitrate reductase activity
L2Z15_05470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z15_05495	COG0426	domain, Protein
L2Z15_05495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z15_05500	COG4774	siderophore transport
L2Z15_05505	COG2119	membrane
L2Z15_05515	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z15_05525	COG4942	peptidase
L2Z15_05540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z15_05550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z15_05570	COG0189	ligase activity
L2Z15_05590	COG0708	Exodeoxyribonuclease III
L2Z15_05595	COG1393	Belongs to the ArsC family
L2Z15_05610	COG3706	GGDEF domain
L2Z15_05645	COG2351	hydroxyisourate hydrolase activity
L2Z15_05650	COG2233	PERMEase
L2Z15_05660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z15_05670	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z15_05680	COG3150	esterase
L2Z15_05740	COG2918	glutathione biosynthetic process
L2Z15_05755	COG2733	membrane
L2Z15_05760	COG0436	Aminotransferase
L2Z15_05765	COG0534	Mate efflux family protein
L2Z15_05850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z15_05855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z15_05865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z15_05875	COG2205	protein histidine kinase activity
L2Z15_05880	COG2826	transposase and inactivated derivatives, IS30 family
L2Z15_05885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z15_05900	COG0010	Belongs to the arginase family
L2Z15_05930	COG2188	Transcriptional regulator
L2Z15_05940	COG0523	cobalamin synthesis protein
L2Z15_05950	COG1113	amino acid transport
L2Z15_05960	COG0625	glutathione transferase activity
L2Z15_05980	COG1683	Conserved Protein
L2Z15_05985	COG0534	Mate efflux family protein
L2Z15_05990	COG0385	Bile acid
L2Z15_05995	COG1335	isochorismatase
L2Z15_06000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z15_06020	COG2116	formate transmembrane transporter activity
L2Z15_06025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z15_06030	COG2133	pyrroloquinoline quinone binding
L2Z15_06035	COG2983	Belongs to the UPF0260 family
L2Z15_06055	COG1194	a g-specific adenine glycosylase
L2Z15_06070	COG2818	Glycosylase
L2Z15_06075	COG1064	alcohol dehydrogenase
L2Z15_06080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z15_06095	COG0583	DNA-binding transcription factor activity
L2Z15_06100	COG0656	L-ascorbic acid biosynthetic process
L2Z15_06105	COG2814	Major facilitator Superfamily
L2Z15_06140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z15_06155	COG2233	PERMEase
L2Z15_06160	COG0583	DNA-binding transcription factor activity
L2Z15_06195	COG0733	neurotransmitter:sodium symporter activity
L2Z15_06235	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z15_06240	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z15_06245	COG0596	Alpha beta hydrolase
L2Z15_06270	COG0488	(ABC) transporter
L2Z15_06275	COG0586	Pfam SNARE associated Golgi protein
L2Z15_06285	COG0187	DNA topoisomerase II activity
L2Z15_06295	COG0592	DNA-directed DNA polymerase activity
L2Z15_06320	COG0706	membrane insertase activity
L2Z15_06335	COG1230	cation diffusion facilitator family transporter
L2Z15_06340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z15_06355	COG0402	S-adenosylhomocysteine deaminase activity
L2Z15_06365	COG0754	glutathionylspermidine amidase activity
L2Z15_06375	COG0861	Integral membrane protein TerC family
L2Z15_06380	COG0671	phosphoesterase, PA-phosphatase related
L2Z15_06390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z15_06405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z15_06410	COG2951	lytic endotransglycosylase activity
L2Z15_06440	COG0583	DNA-binding transcription factor activity
L2Z15_06460	COG0657	acetylesterase activity
L2Z15_06465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z15_06505	COG1047	Peptidyl-prolyl cis-trans
L2Z15_06515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z15_06520	COG0196	riboflavin kinase activity
L2Z15_06530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z15_06535	COG1309	transcriptional regulator
L2Z15_06540	COG1116	anion transmembrane transporter activity
L2Z15_06545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z15_06550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z15_06555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z15_06560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z15_06580	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_06585	COG0546	phosphoglycolate phosphatase activity
L2Z15_06640	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z15_06645	COG0728	peptidoglycan biosynthetic process
L2Z15_06680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z15_06685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z15_06690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z15_06720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z15_06725	COG0110	maltose O-acetyltransferase activity
L2Z15_06735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z15_06750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z15_06755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z15_06765	COG2186	Transcriptional regulator
L2Z15_06775	COG0277	FAD linked oxidase domain protein
L2Z15_06780	COG1448	Aminotransferase
L2Z15_06785	COG1802	Transcriptional regulator
L2Z15_06800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z15_06850	COG0564	pseudouridine synthase activity
L2Z15_06890	COG0251	oxidation-reduction process
L2Z15_06895	COG1113	amino acid transport
L2Z15_06900	COG1113	amino acid transport
L2Z15_06920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z15_06925	COG1960	acyl-CoA dehydrogenase activity
L2Z15_06930	COG1024	Enoyl-CoA hydratase
L2Z15_06935	COG1024	Enoyl-CoA hydratase
L2Z15_06940	COG0477	Major facilitator Superfamily
L2Z15_06945	COG3916	Acyl-homoserine-lactone synthase
L2Z15_06955	COG2197	response regulator
L2Z15_06965	COG1960	acyl-CoA dehydrogenase activity
L2Z15_06970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z15_06970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z15_06970	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z15_06970	COG3321	synthase
L2Z15_06990	COG2267	carboxylic ester hydrolase activity
L2Z15_07010	COG0271	Belongs to the BolA IbaG family
L2Z15_07020	COG1192	Involved in chromosome partitioning
L2Z15_07035	COG0586	Pfam SNARE associated Golgi protein
L2Z15_07040	COG2259	Doxx family
L2Z15_07045	COG4399	Belongs to the UPF0754 family
L2Z15_07050	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z15_07050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z15_07095	COG0281	malic enzyme
L2Z15_07100	COG2837	iron assimilation
L2Z15_07105	COG1280	lysine exporter protein (LysE YggA)
L2Z15_07110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z15_07115	COG1121	(ABC) transporter
L2Z15_07180	COG0386	Belongs to the glutathione peroxidase family
L2Z15_07195	COG1309	transcriptional regulator
L2Z15_07200	COG0697	spore germination
L2Z15_07210	COG0758	DNA mediated transformation
L2Z15_07280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z15_07290	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z15_07330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z15_07340	COG0477	Major facilitator Superfamily
L2Z15_07350	COG1253	flavin adenine dinucleotide binding
L2Z15_07355	COG3012	SEC-C Motif Domain Protein
L2Z15_07360	COG2860	membrane
L2Z15_07365	COG0477	Major facilitator Superfamily
L2Z15_07375	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z15_07390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z15_07410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z15_07450	COG0347	Belongs to the P(II) protein family
L2Z15_07470	COG0004	ammonium transporteR
L2Z15_07480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z15_07480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z15_07520	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z15_07525	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z15_07530	COG0793	Belongs to the peptidase S41A family
L2Z15_07545	COG2197	response regulator
L2Z15_07555	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z15_07565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z15_07570	COG4974	Belongs to the 'phage' integrase family
L2Z15_07595	COG0772	Belongs to the SEDS family
L2Z15_07600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z15_07605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z15_07610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z15_07635	COG0697	spore germination
L2Z15_07640	COG1538	Outer membrane efflux protein
L2Z15_07660	COG3275	phosphorelay sensor kinase activity
L2Z15_07670	COG0181	hydroxymethylbilane synthase activity
L2Z15_07715	COG1716	ATPase activity
L2Z15_07720	COG0546	phosphoglycolate phosphatase activity
L2Z15_07820	COG2056	Na+-H+ antiporter family
L2Z15_07835	COG0326	Molecular chaperone. Has ATPase activity
L2Z15_07850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z15_07910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z15_07915	COG2169	Transcriptional regulator
L2Z15_07915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z15_07945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z15_07955	COG0497	DNA recombination
L2Z15_07970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z15_07980	COG0237	dephospho-CoA kinase activity
L2Z15_08035	COG0195	Participates in both transcription termination and antitermination
L2Z15_08050	COG1320	monovalent cation:proton antiporter activity
L2Z15_08055	COG2212	antiporter activity
L2Z15_08060	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z15_08065	COG0651	ATP synthesis coupled electron transport
L2Z15_08070	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z15_08075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z15_08075	COG2111	Na H antiporter
L2Z15_08090	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z15_08095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z15_08110	COG2226	methyltransferase
L2Z15_08130	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z15_08135	COG1074	ATP-dependent DNA helicase activity
L2Z15_08140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z15_08145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z15_08160	COG0598	Magnesium transport protein CorA
L2Z15_08165	COG0789	Transcriptional regulator
L2Z15_08170	COG0484	heat shock protein binding
L2Z15_08185	COG0475	glutathione-regulated potassium exporter activity
L2Z15_08185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z15_08190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z15_08210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z15_08220	COG4535	Mg2 and Co2 transporter CorC
L2Z15_08225	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z15_08235	COG0644	oxidoreductase
L2Z15_08235	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z15_08245	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z15_08260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z15_08265	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z15_08275	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z15_08275	COG0493	'glutamate synthase
L2Z15_08300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z15_08315	COG0534	Mate efflux family protein
L2Z15_08325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z15_08330	COG4221	oxidoreductase activity
L2Z15_08335	COG0583	DNA-binding transcription factor activity
L2Z15_08350	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z15_08355	COG1530	ribonuclease E activity
L2Z15_08370	COG0546	phosphoglycolate phosphatase activity
L2Z15_08375	COG2378	regulation of single-species biofilm formation
L2Z15_08380	COG0625	glutathione transferase activity
L2Z15_08390	COG0583	DNA-binding transcription factor activity
L2Z15_08445	COG0473	3-isopropylmalate dehydrogenase activity
L2Z15_08500	COG1301	dicarboxylic acid transport
L2Z15_08510	COG1560	Kdo2-lipid A biosynthetic process
L2Z15_08515	COG1280	lysine exporter protein (LysE YggA)
L2Z15_08520	COG0488	(ABC) transporter
L2Z15_08525	COG2900	Belongs to the SlyX family
L2Z15_08535	COG1733	regulation of RNA biosynthetic process
L2Z15_08560	COG0210	DNA helicase
L2Z15_08565	COG0724	RNA recognition motif
L2Z15_08585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z15_08585	COG4651	solute:proton antiporter activity
L2Z15_08610	COG0788	formyltetrahydrofolate deformylase activity
L2Z15_08710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z15_08710	COG2813	Specifically methylates the guanine in position
L2Z15_08720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z15_08730	COG4774	siderophore transport
L2Z15_08740	COG0740	serine-type endopeptidase activity
L2Z15_08760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z15_08760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z15_08765	COG0280	phosphate acetyltransferase
L2Z15_08765	COG0857	belongs to the CobB CobQ family
L2Z15_08770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z15_08780	COG0800	Aldolase
L2Z15_08790	COG3265	gluconokinase activity
L2Z15_08795	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_08805	COG2267	carboxylic ester hydrolase activity
L2Z15_08820	COG0793	Belongs to the peptidase S41A family
L2Z15_08855	COG1426	Protein conserved in bacteria
L2Z15_08895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z15_08905	COG1162	GTPase activity
L2Z15_08910	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z15_08925	COG1538	Outer membrane efflux protein
L2Z15_08930	COG0577	efflux transmembrane transporter activity
L2Z15_08930	COG1136	(ABC) transporter
L2Z15_08935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z15_08960	COG0028	Belongs to the TPP enzyme family
L2Z15_08965	COG0440	acetolactate synthase activity
L2Z15_08995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z15_09010	COG0084	hydrolase, TatD family'
L2Z15_09020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z15_09030	COG0583	DNA-binding transcription factor activity
L2Z15_09040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z15_09045	COG2814	Major facilitator Superfamily
L2Z15_09055	COG0697	spore germination
L2Z15_09085	COG3622	Belongs to the hyi family
L2Z15_09090	COG2084	Dehydrogenase
L2Z15_09095	COG1024	Enoyl-CoA hydratase
L2Z15_09100	COG2205	protein histidine kinase activity
L2Z15_09100	COG0784	Response regulator, receiver
L2Z15_09100	COG5002	protein histidine kinase activity
L2Z15_09120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z15_09130	COG3956	TIGRFAM MazG family protein
L2Z15_09135	COG1555	photosystem II stabilization
L2Z15_09140	COG0617	tRNA 3'-terminal CCA addition
L2Z15_09145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z15_09165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z15_09170	COG3028	Belongs to the UPF0307 family
L2Z15_09175	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z15_09190	COG0625	glutathione transferase activity
L2Z15_09195	COG1238	metal cluster binding
L2Z15_09240	COG0072	phenylalanine-tRNA ligase activity
L2Z15_09270	COG0248	Ppx GppA phosphatase
L2Z15_09280	COG0037	tRNA processing
L2Z15_09320	COG1764	response to oxidative stress
L2Z15_09325	COG1846	Transcriptional regulator
L2Z15_09335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z15_09395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z15_09400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z15_09405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z15_09465	COG1214	PFAM Peptidase M22, glycoprotease
L2Z15_09480	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L2Z15_09490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z15_09495	COG0561	phosphatase activity
L2Z15_09505	COG2132	Multicopper oxidase
L2Z15_09510	COG3667	copper resistance
L2Z15_09525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z15_09530	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z15_09535	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z15_09565	COG1063	alcohol dehydrogenase
L2Z15_09570	COG0583	DNA-binding transcription factor activity
L2Z15_09575	COG1960	acyl-CoA dehydrogenase activity
L2Z15_09580	COG2814	Major facilitator Superfamily
L2Z15_09585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z15_09595	COG1053	succinate dehydrogenase
L2Z15_09600	COG0583	DNA-binding transcription factor activity
L2Z15_09615	COG0583	DNA-binding transcription factor activity
L2Z15_09645	COG0583	DNA-binding transcription factor activity
L2Z15_09660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z15_09665	COG1309	transcriptional regulator
L2Z15_09675	COG2826	transposase and inactivated derivatives, IS30 family
L2Z15_09695	COG0384	phenazine biosynthesis protein PhzF
L2Z15_09705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z15_09725	COG0745	RESPONSE REGULATOR receiver
L2Z15_09765	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z15_09795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z15_09800	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z15_09825	COG0583	DNA-binding transcription factor activity
L2Z15_09845	COG0668	transmembrane transport
L2Z15_09855	COG2081	HI0933 family
L2Z15_09860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z15_09890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z15_09890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z15_09900	COG0489	protein tyrosine kinase activity
L2Z15_09950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z15_09960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z15_09975	COG0730	response to heat
L2Z15_09985	COG1196	nuclear chromosome segregation
L2Z15_10005	COG2223	nitrite transmembrane transporter activity
L2Z15_10010	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z15_10020	COG2226	methyltransferase
L2Z15_10020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z15_10020	COG0596	Alpha beta hydrolase
L2Z15_10035	COG4106	trans-aconitate 2-methyltransferase activity
L2Z15_10050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z15_10055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z15_10060	COG0009	L-threonylcarbamoyladenylate synthase
L2Z15_10065	COG3101	peptidyl-lysine hydroxylation
L2Z15_10070	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z15_10095	COG1652	LysM domain
L2Z15_10100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z15_10100	COG0352	thiamine-phosphate diphosphorylase activity
L2Z15_10100	COG0351	phosphomethylpyrimidine kinase
L2Z15_10110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z15_10140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z15_10170	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z15_10185	COG0358	DNA primase activity
L2Z15_10195	COG0564	pseudouridine synthase activity
L2Z15_10220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z15_10240	COG0583	DNA-binding transcription factor activity
L2Z15_10245	COG0473	3-isopropylmalate dehydrogenase activity
L2Z15_10255	COG0657	acetylesterase activity
L2Z15_10265	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_10285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z15_10285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z15_10300	COG1981	membrane
L2Z15_10345	COG0456	acetyltransferase
L2Z15_10355	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z15_10360	COG0492	ferredoxin-NADP+ reductase activity
L2Z15_10365	COG1674	ftsk spoiiie
L2Z15_10365	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z15_10370	COG1280	lysine exporter protein (LysE YggA)
L2Z15_10385	COG2894	cell division
L2Z15_10400	COG0204	Acyl-transferase
L2Z15_10405	COG2885	chlorophyll binding
L2Z15_10410	COG0210	DNA helicase
L2Z15_10420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z15_10435	COG0121	glutamine amidotransferase
L2Z15_10455	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z15_10460	COG0735	belongs to the Fur family
L2Z15_10485	COG0420	3'-5' exonuclease activity
L2Z15_10505	COG1090	epimerase
L2Z15_10520	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z15_10530	COG2814	Major facilitator Superfamily
L2Z15_10535	COG0405	Gamma-glutamyltransferase
L2Z15_10545	COG0582	viral genome integration into host DNA
L2Z15_10600	COG0629	single-stranded DNA binding
L2Z15_10650	COG0084	hydrolase, TatD family'
L2Z15_10670	COG0477	Major facilitator Superfamily
L2Z15_10675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z15_10685	COG1595	DNA-templated transcription, initiation
L2Z15_10740	COG0531	amino acid
L2Z15_10745	COG2040	homocysteine
L2Z15_10770	COG1309	transcriptional regulator
L2Z15_10775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z15_10780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z15_10790	COG1607	acyl-coa hydrolase
L2Z15_10800	COG0523	cobalamin synthesis protein
L2Z15_10810	COG4681	YaeQ
L2Z15_10820	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z15_10820	COG0726	polysaccharide deacetylase
L2Z15_10825	COG1215	transferase activity, transferring glycosyl groups
L2Z15_10835	COG1024	Enoyl-CoA hydratase
L2Z15_10850	COG1414	Transcriptional regulator
L2Z15_10870	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_10880	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z15_10885	COG2271	Major facilitator Superfamily
L2Z15_10895	COG2267	carboxylic ester hydrolase activity
L2Z15_10900	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_10915	COG0028	Belongs to the TPP enzyme family
L2Z15_10925	COG0477	Major facilitator Superfamily
L2Z15_10930	COG0242	peptide deformylase activity
L2Z15_10935	COG2066	Belongs to the glutaminase family
L2Z15_10940	COG2207	Transcriptional regulator
L2Z15_10945	COG2223	nitrite transmembrane transporter activity
L2Z15_10960	COG0583	DNA-binding transcription factor activity
L2Z15_10965	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_10970	COG2271	Major facilitator Superfamily
L2Z15_10975	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z15_10980	COG3958	Transketolase
L2Z15_10990	COG0306	phosphate transporter
L2Z15_11010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z15_11055	COG4181	ATPase activity
L2Z15_11060	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z15_11085	COG0583	DNA-binding transcription factor activity
L2Z15_11095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z15_11100	COG1773	rubredoxin
L2Z15_11150	COG2851	Citrate transporter
L2Z15_11155	COG1253	flavin adenine dinucleotide binding
L2Z15_11200	COG0804	urea catabolic process
L2Z15_11210	COG0830	nickel cation binding
L2Z15_11225	COG0742	ribosomal rna small subunit methyltransferase
L2Z15_11230	COG0768	penicillin binding
L2Z15_11255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z15_11260	COG2878	Part of a membrane complex involved in electron transport
L2Z15_11265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z15_11275	COG3384	dioxygenase
L2Z15_11300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z15_11625	COG0739	heme binding
L2Z15_11675	COG4372	Transposase
L2Z15_11725	COG0006	proline dipeptidase activity
L2Z15_11730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z15_11735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z15_11755	COG1279	arginine transmembrane transporter activity
L2Z15_11760	COG0583	DNA-binding transcription factor activity
L2Z15_11800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z15_11805	COG0741	lytic transglycosylase activity
L2Z15_11805	COG1388	LysM domain
L2Z15_11805	COG0741	lytic transglycosylase activity
L2Z15_11805	COG1388	LysM domain
L2Z15_11815	COG4174	ABC transporter (Permease)
L2Z15_11820	COG4239	(ABC) transporter, permease
L2Z15_11825	COG4172	Belongs to the ABC transporter superfamily
L2Z15_11845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z15_11855	COG5001	Diguanylate cyclase
L2Z15_11855	COG2203	Gaf domain
L2Z15_11855	COG3706	GGDEF domain
L2Z15_11855	COG4251	negative regulation of phosphorylation
L2Z15_11865	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z15_11865	COG1902	pentaerythritol trinitrate reductase activity
L2Z15_11880	COG4269	membrane
L2Z15_11910	COG3209	COG3209 Rhs family protein
L2Z15_11950	COG1113	amino acid transport
L2Z15_11960	COG0531	amino acid
L2Z15_11980	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_12000	COG1113	amino acid transport
L2Z15_12015	COG0697	spore germination
L2Z15_12020	COG2721	sulfolactate sulfo-lyase activity
L2Z15_12025	COG2271	Major facilitator Superfamily
L2Z15_12030	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z15_12040	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_12045	COG2186	Transcriptional regulator
L2Z15_12100	COG0300	oxidoreductase activity
L2Z15_12110	COG1309	transcriptional regulator
L2Z15_12115	COG1741	Belongs to the pirin family
L2Z15_12130	COG2072	flavoprotein involved in K transport
L2Z15_12140	COG2252	PERMEase
L2Z15_12145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z15_12150	COG3038	cytochrome b561
L2Z15_12160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z15_12170	COG0527	aspartate kinase activity
L2Z15_12180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z15_12190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z15_12205	COG0667	Aldo Keto reductase
L2Z15_12225	COG1765	OsmC-like protein
L2Z15_12240	COG0542	response to heat
L2Z15_12275	COG2885	chlorophyll binding
L2Z15_12285	COG0625	glutathione transferase activity
L2Z15_12290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z15_12310	COG3634	alkyl hydroperoxide reductase activity
L2Z15_12320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z15_12330	COG0450	alkyl hydroperoxide reductase
L2Z15_12335	COG1643	Atp-dependent helicase
L2Z15_12350	COG2814	Major facilitator Superfamily
L2Z15_12355	COG3135	benzoate transporter
L2Z15_12360	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_12365	COG0543	2 iron, 2 sulfur cluster binding
L2Z15_12365	COG0633	Ferredoxin
L2Z15_12370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z15_12375	COG4638	Rieske (2fe-2S)
L2Z15_12385	COG0583	DNA-binding transcription factor activity
L2Z15_12435	COG1570	exodeoxyribonuclease VII activity
L2Z15_12470	COG1278	Cold shock
L2Z15_12505	COG2814	Major facilitator Superfamily
L2Z15_12540	COG0517	IMP dehydrogenase activity
L2Z15_12540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z15_12545	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z15_12555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z15_12560	COG1137	ATPase activity
L2Z15_12570	COG4372	Transposase
L2Z15_12615	COG4122	O-methyltransferase activity
L2Z15_12625	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z15_12640	COG1522	sequence-specific DNA binding
L2Z15_12645	COG5006	permease, DMT superfamily
L2Z15_12655	COG1560	Kdo2-lipid A biosynthetic process
L2Z15_12670	COG2814	Major facilitator Superfamily
L2Z15_12690	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z15_12760	COG0583	DNA-binding transcription factor activity
L2Z15_12765	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z15_12785	COG4770	biotin carboxylase activity
L2Z15_12790	COG0038	chloride channel
L2Z15_12810	COG1309	transcriptional regulator
L2Z15_12820	COG1063	alcohol dehydrogenase
L2Z15_12835	COG0439	Biotin carboxylase
L2Z15_12840	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z15_12860	COG0864	Transcriptional regulator
L2Z15_12870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z15_12875	COG1116	anion transmembrane transporter activity
L2Z15_12995	COG0590	tRNA wobble adenosine to inosine editing
L2Z15_13000	COG2807	transmembrane transport
L2Z15_13015	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z15_13025	COG0789	Transcriptional regulator
L2Z15_13035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z15_13055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z15_13065	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z15_13080	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_13085	COG0531	amino acid
L2Z15_13090	COG1760	l-serine dehydratase
L2Z15_13095	COG2030	dehydratase
L2Z15_13095	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_13100	COG3396	Phenylacetate-CoA oxygenase
L2Z15_13105	COG3460	Phenylacetate-CoA oxygenase
L2Z15_13110	COG3396	Phenylacetate-CoA oxygenase
L2Z15_13115	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z15_13120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z15_13125	COG1024	Enoyl-CoA hydratase
L2Z15_13130	COG1024	Enoyl-CoA hydratase
L2Z15_13135	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z15_13140	COG0183	Belongs to the thiolase family
L2Z15_13145	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z15_13150	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z15_13160	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z15_13190	COG0753	catalase activity
L2Z15_13195	COG3038	cytochrome b561
L2Z15_13215	COG2267	carboxylic ester hydrolase activity
L2Z15_13220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z15_13225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z15_13230	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_13240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z15_13250	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_13255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z15_13260	COG0583	DNA-binding transcription factor activity
L2Z15_13270	COG1414	Transcriptional regulator
L2Z15_13275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z15_13285	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z15_13290	COG3842	ATPase activity
L2Z15_13305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z15_13310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z15_13315	COG2814	Major facilitator Superfamily
L2Z15_13320	COG1960	acyl-CoA dehydrogenase activity
L2Z15_13335	COG1024	Enoyl-CoA hydratase
L2Z15_13345	COG2814	Major facilitator Superfamily
L2Z15_13360	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z15_13365	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_13370	COG1024	Enoyl-CoA hydratase
L2Z15_13375	COG1960	acyl-CoA dehydrogenase activity
L2Z15_13380	COG2814	Major facilitator Superfamily
L2Z15_13385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z15_13390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z15_13400	COG2814	Major facilitator Superfamily
L2Z15_13410	COG1960	acyl-CoA dehydrogenase activity
L2Z15_13425	COG0583	DNA-binding transcription factor activity
L2Z15_13435	COG4770	biotin carboxylase activity
L2Z15_13440	COG1024	Enoyl-CoA hydratase
L2Z15_13445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z15_13450	COG1960	acyl-CoA dehydrogenase activity
L2Z15_13455	COG1309	transcriptional regulator
L2Z15_13460	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z15_13480	COG0583	DNA-binding transcription factor activity
L2Z15_13530	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_13550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z15_13570	COG2205	protein histidine kinase activity
L2Z15_13570	COG0784	Response regulator, receiver
L2Z15_13590	COG0765	amino acid transport
L2Z15_13595	COG0765	amino acid transport
L2Z15_13600	COG1126	abc transporter atp-binding protein
L2Z15_13605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z15_13610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z15_13625	COG1280	lysine exporter protein (LysE YggA)
L2Z15_13635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z15_13640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z15_13645	COG1045	serine acetyltransferase
L2Z15_13660	COG0583	DNA-binding transcription factor activity
L2Z15_13665	COG0625	glutathione transferase activity
L2Z15_13670	COG0625	glutathione transferase activity
L2Z15_13675	COG0583	DNA-binding transcription factor activity
L2Z15_13685	COG1346	cytolysis
L2Z15_13705	COG2814	Major facilitator Superfamily
L2Z15_13715	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z15_13720	COG3052	prosthetic group binding
L2Z15_13740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z15_13760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z15_13770	COG1294	oxidase, subunit
L2Z15_13775	COG1271	oxidase subunit
L2Z15_13800	COG0477	Major facilitator Superfamily
L2Z15_13810	COG4521	taurine ABC transporter
L2Z15_13815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z15_13820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z15_13825	COG2175	clavaminate synthase activity
L2Z15_13835	COG1953	Uracil, thiamine, allantoin
L2Z15_13845	COG0583	DNA-binding transcription factor activity
L2Z15_13855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z15_13870	COG0640	Transcriptional regulator
L2Z15_13875	COG0798	PFAM Bile acid sodium symporter
L2Z15_13880	COG0583	DNA-binding transcription factor activity
L2Z15_13895	COG3634	alkyl hydroperoxide reductase activity
L2Z15_13935	COG0436	Aminotransferase
L2Z15_13945	COG0386	Belongs to the glutathione peroxidase family
L2Z15_13985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z15_14010	COG0012	GTP binding
L2Z15_14015	COG2011	ABC-type metal ion transport system permease component
L2Z15_14020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z15_14030	COG1464	Belongs to the NlpA lipoprotein family
L2Z15_14060	COG0765	amino acid transport
L2Z15_14065	COG0765	amino acid transport
L2Z15_14070	COG1126	abc transporter atp-binding protein
L2Z15_14080	COG1522	sequence-specific DNA binding
L2Z15_14125	COG0583	DNA-binding transcription factor activity
L2Z15_14135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z15_14145	COG0697	spore germination
L2Z15_14170	COG3121	Chaperone
L2Z15_14175	COG3539	Fimbrial protein
L2Z15_14200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z15_14200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z15_14245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z15_14255	COG2353	YceI-like domain
L2Z15_14265	COG3698	Phosphodiester glycosidase
L2Z15_14280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z15_14285	COG0506	proline dehydrogenase activity
L2Z15_14285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z15_14285	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z15_14295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z15_14310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z15_14330	COG1132	(ABC) transporter
L2Z15_14335	COG3122	Protein conserved in bacteria
L2Z15_14340	COG3619	membrane
L2Z15_14350	COG0640	Transcriptional regulator
L2Z15_14360	COG2850	peptidyl-arginine hydroxylation
L2Z15_14365	COG0424	maF-like protein
L2Z15_14385	COG0191	fructose-bisphosphate aldolase activity
L2Z15_14390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z15_14405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z15_14415	COG1192	Involved in chromosome partitioning
L2Z15_14420	COG1475	DNA binding
L2Z15_14425	COG0811	peptide transport
L2Z15_14435	COG1132	(ABC) transporter
L2Z15_14440	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z15_14460	COG0084	hydrolase, TatD family'
L2Z15_14525	COG0776	regulation of translation
L2Z15_14555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z15_14560	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z15_14610	COG0339	signal peptide processing
L2Z15_14620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z15_14655	COG0702	epimerase
L2Z15_14660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z15_14680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z15_14710	COG0316	Belongs to the HesB IscA family
L2Z15_14715	COG0822	iron-sulfur transferase activity
L2Z15_14740	COG0776	regulation of translation
L2Z15_14745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z15_14750	COG2207	Transcriptional regulator
L2Z15_14755	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z15_14760	COG1960	acyl-CoA dehydrogenase activity
L2Z15_14765	COG1960	acyl-CoA dehydrogenase activity
L2Z15_14780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z15_14800	COG4264	IucA IucC family
L2Z15_14805	COG4264	IucA IucC family
L2Z15_14845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z15_14860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z15_14880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z15_14885	COG0730	response to heat
L2Z15_14905	COG4773	Receptor
L2Z15_14910	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z15_14925	COG1131	(ABC) transporter
L2Z15_14930	COG0842	Transport permease protein
L2Z15_14935	COG0842	Transport permease protein
L2Z15_14990	COG2226	methyltransferase
L2Z15_15015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z15_15050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z15_15060	COG0133	tryptophan synthase activity
L2Z15_15075	COG3706	GGDEF domain
L2Z15_15090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z15_15095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z15_15100	COG0022	dehydrogenase e1 component
L2Z15_15105	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z15_15110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z15_15120	COG1063	alcohol dehydrogenase
L2Z15_15125	COG3781	membrane
L2Z15_15135	COG3453	Protein conserved in bacteria
L2Z15_15135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z15_15150	COG0730	response to heat
L2Z15_15165	COG3708	Transcriptional regulator
L2Z15_15165	COG2207	Transcriptional regulator
L2Z15_15170	COG1733	regulation of RNA biosynthetic process
L2Z15_15175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z15_15185	COG2188	Transcriptional regulator
L2Z15_15200	COG4521	taurine ABC transporter
L2Z15_15205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z15_15225	COG0477	Major facilitator Superfamily
L2Z15_15235	COG1027	Aspartate ammonia-lyase
L2Z15_15250	COG0583	DNA-binding transcription factor activity
L2Z15_15255	COG0583	DNA-binding transcription factor activity
L2Z15_15260	COG0183	Belongs to the thiolase family
L2Z15_15265	COG2031	fatty acid transporter
L2Z15_15270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z15_15280	COG0583	DNA-binding transcription factor activity
L2Z15_15290	COG2610	gluconate transmembrane transporter activity
L2Z15_15295	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_15300	COG2207	Transcriptional regulator
L2Z15_15315	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_15340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z15_15340	COG0543	2 iron, 2 sulfur cluster binding
L2Z15_15345	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z15_15350	COG4638	Rieske (2fe-2S)
L2Z15_15360	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z15_15365	COG4149	molybdate abc transporter
L2Z15_15370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z15_15375	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_15380	COG1535	isochorismatase
L2Z15_15380	COG3433	isochorismatase activity
L2Z15_15440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z15_15455	COG0753	catalase activity
L2Z15_15465	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z15_15495	COG3539	Fimbrial protein
L2Z15_15510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z15_15530	COG2072	flavoprotein involved in K transport
L2Z15_15540	COG1538	Outer membrane efflux protein
L2Z15_15545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z15_15550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z15_15555	COG0745	RESPONSE REGULATOR receiver
L2Z15_15560	COG2205	protein histidine kinase activity
L2Z15_15570	COG2207	Transcriptional regulator
L2Z15_15585	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_15630	COG3293	Transposase
L2Z15_15645	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z15_15765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z15_15785	COG1120	ATPase activity
L2Z15_15790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z15_15800	COG1064	alcohol dehydrogenase
L2Z15_15815	COG2207	Transcriptional regulator
L2Z15_15820	COG2084	Dehydrogenase
L2Z15_15830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z15_15835	COG0583	DNA-binding transcription factor activity
L2Z15_15845	COG0129	dihydroxy-acid dehydratase activity
L2Z15_15850	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_15865	COG1566	PFAM secretion protein HlyD family protein
L2Z15_15895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z15_15925	COG0583	DNA-binding transcription factor activity
L2Z15_15950	COG2188	Transcriptional regulator
L2Z15_16000	COG4372	Transposase
L2Z15_16015	COG1473	amidohydrolase
L2Z15_16025	COG0475	glutathione-regulated potassium exporter activity
L2Z15_16025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z15_16035	COG0583	DNA-binding transcription factor activity
L2Z15_16040	COG1335	isochorismatase
L2Z15_16050	COG1309	transcriptional regulator
L2Z15_16080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z15_16090	COG1902	pentaerythritol trinitrate reductase activity
L2Z15_16090	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z15_16095	COG1846	Transcriptional regulator
L2Z15_16120	COG0753	catalase activity
L2Z15_16135	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_16150	COG3162	membrane
L2Z15_16160	COG3829	transcription factor binding
L2Z15_16165	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_16170	COG1960	acyl-CoA dehydrogenase activity
L2Z15_16190	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_16210	COG2186	Transcriptional regulator
L2Z15_16220	COG0583	DNA-binding transcription factor activity
L2Z15_16225	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z15_16230	COG4829	muconolactone delta-isomerase
L2Z15_16240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z15_16245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z15_16250	COG0183	Belongs to the thiolase family
L2Z15_16255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z15_16265	COG1012	belongs to the aldehyde dehydrogenase family
L2Z15_16275	COG3733	amine oxidase
L2Z15_16285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z15_16295	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z15_16305	COG4638	Rieske (2fe-2S)
L2Z15_16325	COG0154	amidase activity
L2Z15_16335	COG2814	Major facilitator Superfamily
L2Z15_16360	COG1960	acyl-CoA dehydrogenase activity
L2Z15_16365	COG0583	DNA-binding transcription factor activity
L2Z15_16370	COG1414	Transcriptional regulator
L2Z15_16385	COG2391	methyltransferase activity
L2Z15_16395	COG4993	Dehydrogenase
L2Z15_16400	COG3659	wide pore channel activity
L2Z15_16405	COG3420	alginic acid biosynthetic process
L2Z15_16410	COG0710	3-dehydroquinate dehydratase activity
L2Z15_16415	COG3485	protocatechuate 3,4-dioxygenase
L2Z15_16420	COG3485	protocatechuate 3,4-dioxygenase
L2Z15_16425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z15_16430	COG2271	Major facilitator Superfamily
L2Z15_16435	COG0596	Alpha beta hydrolase
L2Z15_16440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z15_16445	COG0183	Belongs to the thiolase family
L2Z15_16450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z15_16455	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z15_16465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z15_16470	COG2323	membrane
L2Z15_16515	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z15_16515	COG1902	pentaerythritol trinitrate reductase activity
L2Z15_16540	COG0542	response to heat
L2Z15_16545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z15_16575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z15_16580	COG0569	domain protein
L2Z15_16585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z15_16600	COG4774	siderophore transport
L2Z15_16605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z15_16615	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z15_16630	COG1294	oxidase, subunit
L2Z15_16635	COG4890	Cyd operon protein YbgT
L2Z15_16650	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z15_16660	COG0552	protein localization to endoplasmic reticulum
L2Z15_16685	COG0516	GMP reductase activity
L2Z15_16685	COG0517	IMP dehydrogenase activity
L2Z15_16690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z15_16695	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z15_16705	COG0583	DNA-binding transcription factor activity
L2Z15_16710	COG0024	Methionine aminopeptidase
L2Z15_16740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z15_16740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z15_16745	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z15_16750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z15_16750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z15_16750	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z15_16770	COG3300	MHYT domain
L2Z15_16770	COG5001	Diguanylate cyclase
L2Z15_16800	COG2135	peptidase activity
L2Z15_16805	COG0659	secondary active sulfate transmembrane transporter activity
L2Z15_16825	COG1113	amino acid transport
L2Z15_16835	COG1522	sequence-specific DNA binding
L2Z15_16860	COG1011	Hydrolase
L2Z15_16865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z15_16875	COG2137	regulation of response to DNA damage stimulus
L2Z15_16890	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z15_16925	COG0575	Belongs to the CDS family
L2Z15_16930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z15_16950	COG3852	Histidine kinase
L2Z15_16955	COG2204	response regulator
L2Z15_17010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z15_17015	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z15_17035	COG0697	spore germination
L2Z15_17040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z15_17050	COG0303	'Molybdopterin
L2Z15_17055	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z15_17055	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z15_17070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z15_17075	COG0243	molybdopterin cofactor binding
L2Z15_17085	COG0243	molybdopterin cofactor binding
L2Z15_17090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z15_17095	COG2146	nitrite reductase [NAD(P)H] activity
L2Z15_17095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z15_17105	COG0745	RESPONSE REGULATOR receiver
L2Z15_17110	COG1116	anion transmembrane transporter activity
L2Z15_17110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z15_17130	COG0511	ligase activity, forming carbon-carbon bonds
L2Z15_17145	COG2814	Major facilitator Superfamily
L2Z15_17165	COG0069	glutamate synthase activity
L2Z15_17185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z15_17195	COG1454	alcohol dehydrogenase
L2Z15_17200	COG0824	Thioesterase
L2Z15_17210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z15_17225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z15_17230	COG2030	dehydratase
L2Z15_17240	COG0183	Belongs to the thiolase family
L2Z15_17250	COG0583	DNA-binding transcription factor activity
L2Z15_17255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z15_17265	COG1522	sequence-specific DNA binding
L2Z15_17270	COG3135	benzoate transporter
L2Z15_17280	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z15_17305	COG0589	response to stress
L2Z15_17310	COG0488	(ABC) transporter
L2Z15_17330	COG4773	Receptor
L2Z15_17360	COG0668	transmembrane transport
L2Z15_17370	COG1309	transcriptional regulator
L2Z15_17390	COG1605	Chorismate mutase
L2Z15_17400	COG4221	oxidoreductase activity
L2Z15_17410	COG0308	aminopeptidase N
L2Z15_17430	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z15_17440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z15_17445	COG1454	alcohol dehydrogenase
L2Z15_17465	COG0531	amino acid
L2Z15_17470	COG4303	Ethanolamine ammonia lyase large subunit
L2Z15_17475	COG4302	ethanolamine ammonia-lyase activity
L2Z15_17480	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z15_17480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z15_17485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z15_17495	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z15_17510	COG0697	spore germination
L2Z15_17515	COG1923	regulation of RNA biosynthetic process
L2Z15_17525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z15_17530	COG0802	atpase or kinase
L2Z15_17550	COG1187	pseudouridine synthase activity
L2Z15_17565	COG0583	DNA-binding transcription factor activity
L2Z15_17580	COG2814	Major facilitator Superfamily
L2Z15_17585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z15_17610	COG0729	surface antigen
L2Z15_17630	COG0174	glutamine synthetase
L2Z15_17635	COG0745	RESPONSE REGULATOR receiver
L2Z15_17640	COG2205	protein histidine kinase activity
L2Z15_17650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z15_17655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z15_17680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z15_17685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z15_17690	COG1960	acyl-CoA dehydrogenase activity
L2Z15_17705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z15_17710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z15_17730	COG0583	DNA-binding transcription factor activity
L2Z15_17745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z15_17755	COG3658	cytochrome
L2Z15_17760	COG1215	transferase activity, transferring glycosyl groups
L2Z15_17765	COG0726	polysaccharide deacetylase
L2Z15_17765	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z15_17790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z15_17795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z15_17805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z15_17835	COG0305	Participates in initiation and elongation during chromosome replication
L2Z15_17840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z15_17850	COG1305	Transglutaminase-like
L2Z15_17860	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z15_17890	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z15_17895	COG0138	bifunctional purine biosynthesis protein purh
L2Z15_17900	COG0151	Belongs to the GarS family
L2Z15_17905	COG1464	Belongs to the NlpA lipoprotein family
L2Z15_17910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z15_17915	COG2011	ABC-type metal ion transport system permease component
L2Z15_17920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z15_17930	COG1301	dicarboxylic acid transport
L2Z15_17960	COG1794	racemase activity, acting on amino acids and derivatives
L2Z15_17970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L2Z15_17970	COG3008	intermembrane lipid transfer
L2Z15_17975	COG2995	paraquat-inducible protein a
L2Z15_17985	COG2985	domain, Protein
L2Z15_18015	COG0477	Major facilitator Superfamily
L2Z15_18065	COG2186	Transcriptional regulator
L2Z15_18125	COG3293	Transposase