locus-tag class description EP552_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EP552_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EP552_00030 ENOG4105DQR SNARE associated Golgi EP552_00035 ENOG4105C5H ABC transporter EP552_00040 ENOG4108821 RND type efflux pump EP552_00045 ENOG4108821 RND type efflux pump EP552_00050 ENOG4108821 RND type efflux pump EP552_00060 ENOG4105D74 hydrolase EP552_00065 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) EP552_00070 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) EP552_00115 ENOG4105C8J )-transporter EP552_00125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B EP552_00150 ENOG4108W5M transcriptional regulator EP552_00155 ENOG4105C2W permease EP552_00165 ENOG4108IG5 Transcriptional regulator EP552_00170 ENOG4105DJY efflux transporter, rnd family, mfp subunit EP552_00205 ENOG4105F27 Major Facilitator EP552_00210 ENOG4105CV8 reductase EP552_00215 ENOG4105HEI LysR family (Transcriptional regulator EP552_00235 ENOG4105DQ4 alcohol dehydrogenase EP552_00240 ENOG4108R3E Dna-3-methyladenine glycosylase i EP552_00255 ENOG4105CEN a g-specific adenine glycosylase EP552_00275 ENOG4108ZZ3 UPF0260 protein EP552_00285 ENOG4105D1H recombination factor protein RarA EP552_00290 ENOG4105S64 Formate nitrite transporter EP552_00315 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EP552_00320 ENOG4108RWI nicotinamidase EP552_00325 ENOG4105C09 Bile acid EP552_00330 ENOG4107QI1 Mate efflux family protein EP552_00335 ENOG4105EWC Purine nucleoside phosphorylase EP552_00355 ENOG4108RXX maleylacetoacetate isomerase EP552_00365 ENOG4105C85 amino acid EP552_00375 ENOG4105CKI cobalamin synthesis protein EP552_00385 ENOG4105CZE histidine utilization repressor EP552_00390 ENOG41090B9 response to stress EP552_00405 ENOG4105C85 amino acid EP552_00415 ENOG41088SP formiminoglutamate hydrolase EP552_00430 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EP552_00475 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EP552_00485 ENOG4108ZAI phosphatidylglycerophosphatase a EP552_00490 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) EP552_00505 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EP552_00555 ENOG4105KHC sulfurtransferase EP552_00580 ENOG4105BZU Histidine kinase EP552_00585 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EP552_00600 ENOG4107QJQ Mate efflux family protein EP552_00605 ENOG4105CHM Aminotransferase EP552_00610 ENOG4106BRA Membrane EP552_00625 ENOG4105D9M gamma-glutamylcysteine synthetase EP552_00635 ENOG4105CS6 Rhs element vgr protein EP552_00645 ENOG4106I9N Immunoglobulin G binding protein A EP552_00675 ENOG4105IPS esterase EP552_00680 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EP552_00685 ENOG4105EWI Short-chain dehydrogenase reductase Sdr EP552_00690 ENOG4108Z2U ureidoglycolate hydrolase EP552_00700 ENOG41061H0 Monooxygenase EP552_00715 ENOG41084YZ Hydrolase EP552_00745 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) EP552_00750 ENOG4105BZU Histidine kinase EP552_00765 ENOG4105KUZ arsenate reductase EP552_00770 ENOG4105CGK Exodeoxyribonuclease III EP552_00790 ENOG4105D7Z glutathione synthase EP552_00810 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) EP552_00815 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EP552_00820 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EP552_00835 ENOG41063SB peptidase EP552_00840 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) EP552_00845 ENOG4107QSN dihydrolipoamide acetyltransferase EP552_00860 ENOG4105E0K tonB-dependent siderophore receptor EP552_00875 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EP552_00890 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EP552_00910 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP552_00915 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase EP552_00925 ENOG4105D64 Mechanosensitive ion channel EP552_00935 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EP552_00940 ENOG4108W2Y isochorismatase EP552_00950 ENOG4105FBW Monooxygenase EP552_00955 ENOG4108UZX fmn reductase EP552_00970 ENOG4105BZU Histidine kinase EP552_00975 ENOG41062QD Membrane EP552_00980 ENOG4107QN1 sodium solute EP552_00990 ENOG4105C94 Transporter EP552_01000 ENOG4105BZU Histidine kinase EP552_01010 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EP552_01015 ENOG4108WUH Transcriptional regulator, TetR family EP552_01030 ENOG4105RA2 Membrane EP552_01035 ENOG4105DWF phosphomethylpyrimidine kinase EP552_01045 ENOG4107RDB Major Facilitator EP552_01050 ENOG4108UUM single-stranded DNA-binding protein EP552_01060 ENOG4108UMN azlc family EP552_01070 ENOG4105C85 amino acid EP552_01080 ENOG4108JPW Aminotransferase EP552_01085 ENOG4105C26 Dehydrogenase EP552_01095 ENOG4105CHJ isochorismatase hydrolase EP552_01100 ENOG4105EUB pirin domain protein EP552_01145 ENOG4105D94 Major Facilitator Superfamily EP552_01150 ENOG4106NZI LysR family Transcriptional regulator EP552_01170 ENOG4105CPC Aldo Keto reductase EP552_01175 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) EP552_01205 ENOG4105KVH Transcriptional regulator EP552_01215 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein EP552_01280 ENOG4105CUV Homoserine Kinase EP552_01295 ENOG41061CK Antibiotic biosynthesis monooxygenase EP552_01325 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) EP552_01355 ENOG4105CYC Transferase EP552_01365 ENOG4105E0F Histidine kinase EP552_01370 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EP552_01380 ENOG4105CHH sulfate transporter EP552_01385 ENOG4105PDP Short chain dehydrogenase EP552_01395 ENOG4105C5H ABC transporter EP552_01480 ENOG4108IQI permease EP552_01505 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EP552_01520 ENOG4105CJN penicillin-binding protein EP552_01525 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EP552_01530 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) EP552_01545 ENOG4105DHI Methyltransferase EP552_01550 ENOG4108JQC penicillin-binding protein 1A EP552_01575 ENOG4105E4G Type IV pilus EP552_01595 ENOG4105CBC glutamate synthase EP552_01600 ENOG4105BZ8 glutamate synthase EP552_01610 ENOG4108V0P LemA family EP552_01615 ENOG4105HA9 of methanol dehydrogenase type EP552_01630 ENOG4108YSG O-Antigen polymerase EP552_01635 ENOG4108UQY Iron-storage protein EP552_01645 ENOG4105KME endoribonuclease L-psp EP552_01650 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EP552_01665 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) EP552_01715 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) EP552_01730 ENOG4107IFA Lipase (EC 3.1.1.3) EP552_01735 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) EP552_01740 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) EP552_01765 ENOG4108JQ1 Dehydrogenase EP552_01770 ENOG4105CQB FAD linked oxidase domain protein EP552_01780 ENOG4105VRH Antibiotic biosynthesis monooxygenase EP552_01785 ENOG4105NF4 modulator of drug activity EP552_01795 ENOG4107QF7 multi-drug EP552_01815 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EP552_01820 ENOG4105IPI Membrane EP552_01825 ENOG4107SKI cobyrinic Acid a,c-diamide synthase EP552_01855 ENOG4108IQI permease EP552_01860 ENOG4105D82 Glutamate dehydrogenase EP552_01865 ENOG4105C8Y Acetylornithine aminotransferase EP552_01875 ENOG4105C26 Dehydrogenase EP552_01900 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin EP552_01965 ENOG4105W87 Cbs domain EP552_01970 ENOG41067S9 phage shock protein C, PspC EP552_01980 ENOG4105CSU acyl-Coa dehydrogenase EP552_01995 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) EP552_02010 ENOG4105ECY inositol monophosphatase EP552_02015 ENOG4105C1J atp-dependent rna helicase EP552_02025 ENOG4105DHJ ABC, transporter EP552_02030 ENOG4105CY3 ABC transporter, permease EP552_02040 ENOG4105E3I toluene tolerance EP552_02050 ENOG4105D7N magnesium and cobalt transport protein CorA EP552_02055 ENOG4108URH decarboxylase EP552_02065 ENOG4105MJ2 Competence protein EP552_02070 ENOG4105CB5 ATP-dependent DNA helicase recG EP552_02090 ENOG4105C29 acyl-CoA thioesterase EP552_02095 ENOG4105CK2 sodium dicarboxylate symporter EP552_02110 ENOG4105KPV Transcriptional regulator EP552_02120 ENOG4105D7A ATP-binding protein EP552_02125 ENOG4105C28 cystathionine EP552_02130 ENOG41089BK Glutamine amido-transferase EP552_02240 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EP552_02245 ENOG41067V7 50S ribosomal protein L36 EP552_02255 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) EP552_02280 ENOG4105C1G acyl-Coa dehydrogenase EP552_02315 ENOG4105VKU nucleicacid-binding protein EP552_02320 ENOG4105DGW oligopeptidase A EP552_02325 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EP552_02365 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase EP552_02370 ENOG4108K2B transcriptional regulator EP552_02380 ENOG4107S2Z UPF0761 membrane protein EP552_02385 ENOG4105CS1 NAD(P)H quinone oxidoreductase EP552_02415 ENOG4105C9A Phoh family EP552_02425 ENOG4105E4C Lytic transglycosylase catalytic EP552_02455 ENOG4105D6S protein involved in catabolism of external DNA EP552_02460 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EP552_02505 ENOG4105C1G acyl-Coa dehydrogenase EP552_02510 ENOG4108RZE Tetr family transcriptional regulator EP552_02525 ENOG4107QX3 carboxylase EP552_02530 ENOG4105C1G acyl-Coa dehydrogenase EP552_02550 ENOG4105KB2 stringent starvation protein b EP552_02555 ENOG4107MKT Stringent starvation protein a EP552_02560 ENOG4108UJD 30S ribosomal protein S9 EP552_02570 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EP552_02575 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) EP552_02580 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) EP552_02600 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EP552_02610 ENOG4107RZC phospholipase d EP552_02620 ENOG4105UYK outer membrane protein a EP552_02630 ENOG4108KHX Diguanylate cyclase EP552_02665 ENOG4107QN2 dihydrolipoyl dehydrogenase EP552_02675 ENOG4107QPB Beta-lactamase domain protein EP552_02680 ENOG4107U2T alpha beta EP552_02690 ENOG4105NAU thioesterase Superfamily protein EP552_02720 ENOG4105K9H YciI-like protein EP552_02730 ENOG4105DB7 PHP domain protein EP552_02735 ENOG4105FFC UPF0187 protein EP552_02745 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EP552_02750 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EP552_02755 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EP552_02760 ENOG4105VIE preprotein translocase, subunit YajC EP552_02790 ENOG4105BZU Histidine kinase EP552_02795 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) EP552_02800 ENOG4105CM2 brancheD-chain amino acid aminotransferase EP552_02815 ENOG4107BJW polysaccharide deacetylase EP552_02825 ENOG4108PQP glycosyl transferase group 1 EP552_02845 ENOG4105F9F transposase EP552_02885 ENOG4105UGU tonB-dependent Receptor EP552_02905 ENOG4108VY7 phosphate-starvation-inducible protein PsiE EP552_02910 ENOG4105CSU acyl-Coa dehydrogenase EP552_02915 ENOG4105CSU acyl-Coa dehydrogenase EP552_02925 ENOG4105EB3 Histidine kinase EP552_02930 ENOG4105E3W Two component transcriptional regulator (Winged helix family EP552_02935 ENOG4105CNG UPF0061 protein EP552_02955 ENOG4108WBT adenosyltransferase EP552_02970 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EP552_03005 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EP552_03025 ENOG4105D3R alkyl hydroperoxide reductase EP552_03040 ENOG4105CSH Transporter EP552_03045 ENOG4108UT2 hemolysin iii EP552_03075 ENOG4105CHU acetyl-coa acetyltransferase EP552_03080 ENOG4108R6W Transcriptional regulator, ARAC family EP552_03090 ENOG4105TW1 Carbohydrate-selective porin OprB EP552_03095 ENOG4105DZG Dehydrogenase EP552_03100 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EP552_03110 ENOG410814C multidrug resistance protein EP552_03120 ENOG4105CHU acetyl-coa acetyltransferase EP552_03130 ENOG4108WHA ompa motb domain protein EP552_03135 ENOG4105E0Y RtcB Protein EP552_03140 ENOG4108IQI permease EP552_03150 ENOG4105C2W permease EP552_03170 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EP552_03180 ENOG4108VX5 3-methyladenine DNA glycosylase EP552_03190 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP552_03195 ENOG4108N2Y auxin Efflux EP552_03205 ENOG4105T95 Thiol disulfide interChange protein EP552_03210 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) EP552_03220 ENOG4105K78 MarR family Transcriptional regulator EP552_03225 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EP552_03230 ENOG4105KWI UPF0339 protein EP552_03255 ENOG4108UNF response regulator EP552_03260 ENOG4105M3Z response regulator EP552_03265 ENOG4108ZGA chew protein EP552_03270 ENOG4105C8Q Methyl-accepting chemotaxis EP552_03290 ENOG4106HKS Entericidin EcnA/B family EP552_03300 ENOG4105WD1 Membrane EP552_03305 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EP552_03345 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) EP552_03355 ENOG4105EM2 membrane EP552_03360 ENOG4105C2C drug resistance transporter, Bcr CflA EP552_03380 ENOG4105BZG amino acid carrier protein EP552_03385 ENOG4105D78 K07001 NTE family protein EP552_03390 ENOG4105C7B Threonine dehydratase EP552_03425 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EP552_03435 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EP552_03440 ENOG4105DFF Rod shape-determining protein mreb EP552_03445 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EP552_03450 ENOG4105VQ7 Rod shape-determining protein MreD EP552_03455 ENOG4108Z03 MAF-like protein EP552_03460 ENOG4105C03 ribonuclease EP552_03470 ENOG4105D8T Acyltransferase EP552_03480 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein EP552_03490 ENOG4108X0B nad(p)h dehydrogenase (quinone) EP552_03515 ENOG4105CF7 AraC family transcriptional regulator EP552_03535 ENOG4105C85 amino acid EP552_03540 ENOG4105C7F AcnD-accessory protein PrpF EP552_03545 ENOG4105CTB Polyprenyl synthetase EP552_03550 ENOG4105MSB protein, conserved in bacteria EP552_03565 ENOG4105D78 K07001 NTE family protein EP552_03585 ENOG4105DIJ Phosphoethanolamine transferase EP552_03590 ENOG4105XJC Two component transcriptional regulator (Winged helix family EP552_03595 ENOG4105DHQ Histidine kinase EP552_03615 ENOG4108M0I Transcriptional regulator EP552_03635 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) EP552_03655 ENOG4105K8R UPF0145 protein EP552_03660 ENOG4105K8R UPF0145 protein EP552_03665 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EP552_03670 ENOG4105BZS acriflavin resistance protein EP552_03675 ENOG4105C1P efflux transporter, rnd family, mfp subunit EP552_03680 ENOG410841Q phosphoesterase PA-phosphatase related protein EP552_03710 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) EP552_03725 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EP552_03730 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EP552_03735 ENOG4105KVH Transcriptional regulator EP552_03745 ENOG4105CUB amino acid EP552_03760 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) EP552_03765 ENOG41084BA UPF0250 protein EP552_03770 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EP552_03805 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit EP552_03810 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein EP552_03820 ENOG4105E33 succinate dehydrogenase EP552_03835 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 EP552_03840 ENOG4105C7S Dehydrogenase EP552_03845 ENOG4107QN2 dihydrolipoyl dehydrogenase EP552_03855 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EP552_03865 ENOG4105CKW Inner membrane protein yedI EP552_03870 ENOG4105CGZ zinc metallopeptidase EP552_03875 ENOG4105EEQ Na H antiporter EP552_03965 ENOG4105PNM synthesis protein EP552_03980 ENOG41080TK Universal stress protein EP552_03995 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain EP552_04000 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain EP552_04015 ENOG4105HBR Rna-binding protein EP552_04025 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EP552_04030 ENOG4105EEI dihydropteroate synthase EP552_04085 ENOG4105CSH Transporter EP552_04090 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EP552_04095 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EP552_04110 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EP552_04130 ENOG41080IJ Diacylglycerol kinase EP552_04140 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase EP552_04145 ENOG4105BZS acriflavin resistance protein EP552_04160 ENOG4105E4C Lytic transglycosylase catalytic EP552_04185 ENOG4108RRZ Transcription elongation factor GreB EP552_04200 ENOG4105CEY Amp-dependent synthetase and ligase EP552_04210 ENOG4105F9F transposase EP552_04255 ENOG4105BZW Glycerate kinase EP552_04260 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit EP552_04265 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EP552_04280 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) EP552_04290 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EP552_04295 ENOG4105C85 amino acid EP552_04305 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EP552_04315 ENOG4105N14 lysine exporter protein LysE YggA EP552_04320 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EP552_04325 ENOG4105BZJ Electron transfer flavoprotein EP552_04330 ENOG4105C10 Electron transfer flavoprotein EP552_04335 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EP552_04370 ENOG4107KET secretion protein, HlyD family EP552_04400 ENOG4105D60 lipoprotein releasing system transmembrane protein EP552_04405 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) EP552_04410 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EP552_04420 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) EP552_04425 ENOG4107R6F Alpha Beta Hydrolase Fold protein EP552_04430 ENOG4108V3E phosphoribosylglycinamide formyltransferase EP552_04440 ENOG4105C02 permease EP552_04500 ENOG4105KCK Peptidoglycan-associated lipoprotein EP552_04505 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) EP552_04515 ENOG4105M8F Biopolymer transport protein exbD tolR EP552_04520 ENOG4105E02 MotA TolQ exbB proton channel EP552_04525 ENOG4107YD3 Thioesterase EP552_04530 ENOG4105CH2 amidohydrolase EP552_04550 ENOG4108ETH Formylglycinamide ribotide synthetase EP552_04555 ENOG4105C2C drug resistance transporter, Bcr CflA EP552_04560 ENOG4105EGD dinuclear metal center protein, YbgI family EP552_04565 ENOG4108UKI Enoyl-CoA hydratase EP552_04580 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EP552_04595 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) EP552_04600 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EP552_04615 ENOG4107R11 Transcriptional regulator EP552_04620 ENOG4108IJ6 ABC transporter EP552_04630 ENOG4108I5D sulfate abc transporter EP552_04640 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EP552_04645 ENOG4105YAZ 4-amino-4-deoxychorismate lyase EP552_04650 ENOG4105HHA aminodeoxychorismate lyase EP552_04665 ENOG4108IYU L-aspartate oxidase EP552_04670 ENOG4105C0H protease EP552_04685 ENOG4105C3F Signal peptidase i EP552_04700 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) EP552_04710 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) EP552_04715 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) EP552_04720 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase EP552_04725 ENOG4105EMU Dehydrogenase EP552_04765 ENOG4105BZU Histidine kinase EP552_04775 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EP552_04785 ENOG4105DTR rard protein EP552_04830 ENOG4107QS8 (LipO)protein EP552_04835 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EP552_04840 ENOG4105EA8 2-Nitropropane dioxygenase EP552_04870 ENOG4107R8N Glycosyl transferase, family 2 EP552_04885 ENOG4105CVP deoxyribo-dipyrimidine photolyase EP552_04890 ENOG4108YZY peptidylprolyl cis-trans isomerase EP552_04895 ENOG4105CEP NADH dehydrogenase EP552_04900 ENOG4105DZ1 carboxypeptidase EP552_04910 ENOG4105E9K Isocitrate dehydrogenase EP552_04915 ENOG4108R99 pseudouridine synthase EP552_04940 ENOG4105CBP Major Facilitator EP552_04945 ENOG4105EGI Transcriptional regulator EP552_04950 ENOG4108ETY sodium dicarboxylate symporter EP552_04955 ENOG4105JAB phenazine biosynthesis protein, phzf family EP552_04985 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) EP552_05000 ENOG4105D3G Pseudouridine synthase EP552_05005 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) EP552_05020 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EP552_05045 ENOG4108JPW Aminotransferase EP552_05050 ENOG4105DY8 decarboxylase EP552_05060 ENOG4105F7P transcriptional regulator AsnC family EP552_05065 ENOG4107RA9 decarboxylase EP552_05070 ENOG4105C85 amino acid EP552_05075 ENOG4105CVA phosphate EP552_05080 ENOG4105C8U phosphate abc transporter EP552_05090 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EP552_05095 ENOG4105ERU peptidase EP552_05110 ENOG4107QTF adenylosuccinate lyase EP552_05130 ENOG4108Z0R Transferase EP552_05135 ENOG4105DZ1 carboxypeptidase EP552_05155 ENOG4108K5P (LipO)protein EP552_05160 ENOG4105EJC lysr family transcriptional regulator EP552_05165 ENOG4105DAN ATP-dependent protease EP552_05180 ENOG4105DHU Bile acid EP552_05200 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EP552_05210 ENOG4105D22 carbon starvation protein EP552_05215 ENOG4105VCD cytoplasmic protein EP552_05250 ENOG4108K8K Transcriptional regulator EP552_05265 ENOG4105C26 Dehydrogenase EP552_05270 ENOG4105C85 amino acid EP552_05275 ENOG4105ETT transcriptional Regulator, LysR family EP552_05280 ENOG4105C94 Transporter EP552_05285 ENOG4105C94 Transporter EP552_05295 ENOG4105C26 Dehydrogenase EP552_05300 ENOG4107QZF nitrite reductase NADPH large subunit EP552_05305 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) EP552_05335 ENOG41060M8 Pfam:PhdYeFM EP552_05340 ENOG4107QNK )-transporter EP552_05345 ENOG4107WEA mandelate racemase muconate lactonizing EP552_05355 ENOG4105J7D transcriptional regulator EP552_05375 ENOG4105C2I pirin domain protein EP552_05385 ENOG4105WWK YheO domain protein EP552_05400 ENOG4105CEY Amp-dependent synthetase and ligase EP552_05415 ENOG4108IPW abc transporter atp-binding protein EP552_05445 ENOG4105C0W non-ribosomal peptide synthetase EP552_05450 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EP552_05455 ENOG4105WQI isochorismatase EP552_05470 ENOG4105BZ1 (ABC) transporter EP552_05490 ENOG4105E4F Isochorismate synthase EP552_05505 ENOG4105NX3 Membrane EP552_05520 ENOG41066YJ Beta-lactamase EP552_05530 ENOG4105EUJ GTP cyclohydrolase i EP552_05540 ENOG4105C7W Xanthine dehydrogenase EP552_05570 ENOG4105CD8 aminopeptidase N EP552_05575 ENOG4105DDQ anthranilate synthase EP552_05885 ENOG4105DIJ Phosphoethanolamine transferase EP552_05920 ENOG4107RAQ aminopeptidase EP552_05925 ENOG4105D0A hydroxylase EP552_05930 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EP552_05950 ENOG4108ZUB Lysine exporter protein (Lyse ygga) EP552_05955 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) EP552_05965 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EP552_05975 ENOG4105W4M Transport-associated protein EP552_05985 ENOG4105E09 nadh pyrophosphatase EP552_05995 ENOG4107RZZ dna polymerase iii epsilon subunit EP552_06000 ENOG4105E9H Lytic Murein transglycosylase EP552_06000 ENOG4105E9H Lytic Murein transglycosylase EP552_06010 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EP552_06015 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EP552_06020 ENOG4108JQ5 ABC transporter EP552_06040 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) EP552_06060 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP552_06075 ENOG4108M3P Membrane EP552_06080 ENOG4105D01 (LipO)protein EP552_06130 ENOG4105F9F transposase EP552_06140 ENOG4105F95 Monooxygenase EP552_06150 ENOG4105C7N Xanthine uracil vitamin C permease EP552_06155 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) EP552_06160 ENOG4105CPW cytochrome b561 EP552_06170 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) EP552_06180 ENOG4105CFH Aspartokinase EP552_06190 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EP552_06200 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis EP552_06215 ENOG4105CPC Aldo Keto reductase EP552_06220 ENOG4107RYR Transcriptional regulator, Crp Fnr family EP552_06225 ENOG4108UKZ OsmC family EP552_06240 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EP552_06270 ENOG4105CD3 dihydroorotase EP552_06275 ENOG4108ZG0 Ompa motb domain protein EP552_06285 ENOG4108TGY Glutathione S-transferase EP552_06290 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) EP552_06300 ENOG4108K3A Glutathione S-transferase EP552_06310 ENOG4108JU3 Alkyl hydroperoxide reductase EP552_06320 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) EP552_06330 ENOG4105D3R alkyl hydroperoxide reductase EP552_06335 ENOG4105CQ7 ATP-dependent helicase EP552_06350 ENOG4105D2S major facilitator superfamily EP552_06355 ENOG4105DKK Benzoate EP552_06360 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase EP552_06365 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein EP552_06370 ENOG4108UKV benzoate 1,2-dioxygenase EP552_06375 ENOG4105FUY alpha subunit EP552_06380 ENOG4108KB2 LysR family Transcriptional regulator EP552_06445 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) EP552_06480 ENOG410829K Lysine exporter protein (Lyse ygga) EP552_06485 ENOG4105VEQ Cold shock protein EP552_06495 ENOG4105II7 pyrroline-5-carboxylate reductase EP552_06530 ENOG4107YPT transcriptional regulator EP552_06545 ENOG4105F9F transposase EP552_06555 ENOG4105F9F transposase EP552_06580 ENOG4105C2X Arabinose 5-phosphate isomerase EP552_06585 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase EP552_06595 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA EP552_06600 ENOG4108IUZ ABC transporter EP552_06605 ENOG4105DFG type I secretion outer membrane protein EP552_06645 ENOG4108Z4U Ferredoxin EP552_06665 ENOG4107AQZ Membrane EP552_06670 ENOG4105BZU Histidine kinase EP552_06675 ENOG4105D1S lipid A biosynthesis EP552_06690 ENOG4105D2S major facilitator superfamily EP552_06710 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) EP552_06760 ENOG4105CNA YD repeat protein EP552_06775 ENOG4108WAV Transcriptional regulator EP552_06780 ENOG4105C5A transporter EP552_06800 ENOG4108JIK carboxylase EP552_06805 ENOG4107R4J Chloride channel EP552_06830 ENOG4105R8C Transcriptional regulator EP552_06840 ENOG4105E2A Dehydrogenase EP552_06865 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EP552_06870 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF EP552_06890 ENOG4105MRR Transcriptional regulator (By similarity) EP552_06900 ENOG4108HW3 (ABC) transporter EP552_06980 ENOG4105UYK outer membrane protein a EP552_06990 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EP552_07020 ENOG4105EMY transcriptional regulator EP552_07030 ENOG4107Y2X deaminase EP552_07035 ENOG4105DJ2 Major Facilitator Superfamily EP552_07050 ENOG4105WPN DNA integration recombination invertion protein EP552_07060 ENOG4108Z4X TRANSCRIPTIONal EP552_07075 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EP552_07095 ENOG4105MWK D-amino acid dehydrogenase, small subunit EP552_07120 ENOG4105CZJ Aldehyde dehydrogenase EP552_07125 ENOG4107QTZ amino acid EP552_07130 ENOG4105EJQ L-serine dehydratase EP552_07135 ENOG4105DXM phenylacetic acid degradation protein EP552_07140 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit EP552_07145 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit EP552_07150 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit EP552_07155 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit EP552_07160 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EP552_07165 ENOG4105E39 Enoyl-CoA hydratase EP552_07170 ENOG4108UKI Enoyl-CoA hydratase EP552_07175 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EP552_07180 ENOG4105CHU acetyl-coa acetyltransferase EP552_07185 ENOG4105DZS Phenylacetate-CoA ligase EP552_07190 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein EP552_07200 ENOG4107YAU phenylacetic acid degradation protein EP552_07210 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EP552_07250 ENOG4105VEQ Cold shock protein EP552_07260 ENOG4105CF7 AraC family transcriptional regulator EP552_07340 ENOG4107HP6 Transcriptional regulator EP552_07345 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase EP552_07360 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EP552_07365 ENOG4107RCV ABC transporter, permease EP552_07375 ENOG4107STF Involved in phosphonate degradation (By similarity) EP552_07380 ENOG4108KAZ Involved in phosphonate degradation (By similarity) EP552_07385 ENOG4107RGD Major Facilitator superfamily EP552_07390 ENOG4105C1G acyl-Coa dehydrogenase EP552_07405 ENOG4108UKI Enoyl-CoA hydratase EP552_07410 ENOG4105EA8 2-Nitropropane dioxygenase EP552_07415 ENOG4105EQ0 Major Facilitator superfamily EP552_07425 ENOG4105CHU acetyl-coa acetyltransferase EP552_07430 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EP552_07435 ENOG4105CHR reductase EP552_07440 ENOG4105E39 Enoyl-CoA hydratase EP552_07445 ENOG4105C1G acyl-Coa dehydrogenase EP552_07450 ENOG4107RGD Major Facilitator superfamily EP552_07455 ENOG4107QP7 CoA-transferase subunit A EP552_07460 ENOG4107QNJ CoA-transferase subunit B EP552_07470 ENOG4105EQ0 Major Facilitator superfamily EP552_07480 ENOG4105CSU acyl-Coa dehydrogenase EP552_07495 ENOG4105CC0 LysR family Transcriptional regulator EP552_07510 ENOG4105E39 Enoyl-CoA hydratase EP552_07515 ENOG4107QX3 carboxylase EP552_07520 ENOG4105C1G acyl-Coa dehydrogenase EP552_07525 ENOG4105R8C Transcriptional regulator EP552_07530 ENOG4105CEY Amp-dependent synthetase and ligase EP552_07550 ENOG4105HEI LysR family (Transcriptional regulator EP552_07595 ENOG4105CYX Short-chain dehydrogenase reductase Sdr EP552_07615 ENOG4105KT5 UmuD protein EP552_07625 ENOG4105EW9 transcriptional regulator AsnC family EP552_07635 ENOG4105BZU Histidine kinase EP552_07640 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EP552_07655 ENOG4105EAD ABC transporter EP552_07660 ENOG4108HW4 amino acid AbC transporter EP552_07665 ENOG4105CDA abc transporter atp-binding protein EP552_07670 ENOG4107RP9 extracellular solute-binding protein, family 3 EP552_07675 ENOG4105CT1 (ABC) transporter EP552_07685 ENOG4105EXG Transcriptional regulator EP552_07700 ENOG4105C9B Cysteine desulfurase EP552_07705 ENOG4105ESN nucleotide-binding protein EP552_07710 ENOG4105D7W serine acetyltransferase EP552_07720 ENOG4105CHR reductase EP552_07725 ENOG4105CBN LysR family transcriptional regulator EP552_07730 ENOG4105CYM Glutathione S-transferase EP552_07735 ENOG4108SHQ Glutathione S-transferase EP552_07740 ENOG4105CMU LysR family (Transcriptional regulator EP552_07745 ENOG4105VAW lrga family EP552_07750 ENOG41067MG lrgb family EP552_07770 ENOG4105DXI Major Facilitator superfamily EP552_07780 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase EP552_07785 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) EP552_07800 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase EP552_07805 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EP552_07820 ENOG4108K70 Transcriptional regulator EP552_07825 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EP552_07835 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EP552_07840 ENOG4105C4M (Ubiquinol oxidase) subunit I EP552_07865 ENOG4105C54 Major Facilitator superfamily EP552_07885 ENOG4106FTQ Taurine ABC transporter, periplasmic EP552_07890 ENOG4108IY8 ABC, transporter EP552_07895 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EP552_07900 ENOG4105E2B Taurine dioxygenase EP552_07910 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EP552_07920 ENOG4105CBN LysR family transcriptional regulator EP552_07930 ENOG4105CPN adenine deaminase EP552_07945 ENOG41082YX Transcriptional regulator, arsr family EP552_07950 ENOG4105D6J arsenicaL-resistance protein EP552_07955 ENOG4108KB2 LysR family Transcriptional regulator EP552_07970 ENOG4108JU3 Alkyl hydroperoxide reductase EP552_07995 ENOG4105C0B DNA polymerase III (alpha subunit) EP552_08015 ENOG4105CHM Aminotransferase EP552_08025 ENOG4108V06 Glutathione peroxidase EP552_08030 ENOG4105E7U AraC family transcriptional regulator EP552_08060 ENOG4105ZED uncharacterized protein ygaH EP552_08065 ENOG4108UMN azlc family EP552_08090 ENOG4105C3G gtp-binding protein EP552_08095 ENOG4108UMI ABC transporter, permease EP552_08100 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EP552_08105 ENOG4105D01 (LipO)protein EP552_08110 ENOG4105D01 (LipO)protein EP552_08125 ENOG4107T8P acyl-Coa dehydrogenase EP552_08140 ENOG4105EAD ABC transporter EP552_08145 ENOG4105DRP amino acid AbC transporter EP552_08150 ENOG4105CDA abc transporter atp-binding protein EP552_08160 ENOG4105EW9 transcriptional regulator AsnC family EP552_08175 ENOG41067SE Tetr family transcriptional regulator EP552_08205 ENOG4105CC0 LysR family Transcriptional regulator EP552_08215 ENOG4105ETS cytosine purines uracil thiamine allantoin EP552_08225 ENOG4108IPJ Membrane EP552_08260 ENOG4105GQR Chaperone EP552_08265 ENOG4105X0I Fimbrial EP552_08285 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EP552_08290 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) EP552_08310 ENOG4108HWY Beta-lactamase EP552_08340 ENOG4105CV1 Transketolase (EC 2.2.1.1) EP552_08350 ENOG4108YYC ycei family EP552_08360 ENOG4108T58 Mg2 transport protein CorA EP552_08375 ENOG4105YGK Pfam:UPF0157 EP552_08380 ENOG4105C26 Dehydrogenase EP552_08385 ENOG4105EW9 transcriptional regulator AsnC family EP552_08390 ENOG4105CK7 Sodium proline symporter EP552_08395 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EP552_08405 ENOG4108ZX5 transcriptional regulator EP552_08415 ENOG4105BZ1 (ABC) transporter EP552_08420 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme EP552_08425 ENOG4105XPP Protein of unknown function (DUF1275) EP552_08435 ENOG41080HT Transcriptional regulator, arsr family EP552_08445 ENOG4105EZE Cupin 4 family protein EP552_08450 ENOG4108UHJ MAF-like protein EP552_08470 ENOG4105D2N Aldolase EP552_08475 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EP552_08480 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) EP552_08485 ENOG4105EHM Aminoglycoside phosphotransferase EP552_08490 ENOG4108S0S Nucleotidyl transferase EP552_08500 ENOG4107QJE Chromosome Partitioning Protein EP552_08505 ENOG4105FA0 parb-like partition protein EP552_08520 ENOG4105BZ1 (ABC) transporter EP552_08525 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) EP552_08535 ENOG4107QRG dna polymerase iii EP552_08545 ENOG4105F8V Hydrolase, tatD family EP552_08570 ENOG4108RTD type II secretion system protein K EP552_08590 ENOG4108Z6B deaminase EP552_08605 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) EP552_08610 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) EP552_08630 ENOG4107RN6 Monooxygenase EP552_08640 ENOG4105D6Z AFG1 family ATPase EP552_08710 ENOG4105CDU Replicative dna helicase EP552_08785 ENOG4105EFC phage portal protein HK97 family EP552_08840 ENOG4105E4C Lytic transglycosylase catalytic EP552_08895 ENOG4107QP3 malate synthase g EP552_08905 ENOG4105SG9 biopolymer transport protein, ExbD EP552_08945 ENOG4105DGW oligopeptidase A EP552_08955 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EP552_08975 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase EP552_08990 ENOG4105K4T epimerase EP552_08995 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) EP552_09015 ENOG4108JA2 transcriptioN-repair coupling factor EP552_09025 ENOG4105F8J Adenylate Guanylate cyclase EP552_09030 ENOG4108ZIT Ferredoxin, 2FE-2S EP552_09045 ENOG4108Z4V iron-sulfur cluster assembly EP552_09050 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins EP552_09060 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family EP552_09075 ENOG4105K70 DNA-binding protein EP552_09080 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EP552_09085 ENOG4105E7U AraC family transcriptional regulator EP552_09090 ENOG4105EEF Alkane 1-monooxygenase EP552_09095 ENOG4105C1G acyl-Coa dehydrogenase EP552_09100 ENOG4105C1G acyl-Coa dehydrogenase EP552_09115 ENOG4108Z66 YbaK ebsC protein EP552_09135 ENOG4105DUU IucA IucC family protein EP552_09140 ENOG4105DJU Siderophore biosynthesis protein EP552_09195 ENOG4108YZT Adenosylcobinamide kinase EP552_09200 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) EP552_09220 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EP552_09225 ENOG4107TSN permease EP552_09245 ENOG4105CNM Receptor EP552_09250 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EP552_09285 ENOG4105CJ1 ABC, transporter EP552_09290 ENOG4107QWP ABC-2 type transporter EP552_09295 ENOG4107QWP ABC-2 type transporter EP552_09320 ENOG4105K59 histidine triad (HIT) protein EP552_09350 ENOG4105F2W methyltransferase EP552_09360 ENOG4105C28 cystathionine EP552_09375 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) EP552_09420 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EP552_09425 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) EP552_09450 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EP552_09455 ENOG4107R0V Pyruvate dehydrogenase EP552_09460 ENOG4105CPP Dehydrogenase, E1 component EP552_09475 ENOG4105CHR reductase EP552_09485 ENOG4105FFC UPF0187 protein EP552_09495 ENOG4107QPB Beta-lactamase domain protein EP552_09505 ENOG4108VCT Sulfite exporter TauE/SafE EP552_09520 ENOG4105UEI Transcriptional Regulator AraC Family EP552_09525 ENOG4105KVH Transcriptional regulator EP552_09530 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) EP552_09540 ENOG4105FDP GntR family transcriptional regulator EP552_09555 ENOG4106FTQ Taurine ABC transporter, periplasmic EP552_09560 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EP552_09580 ENOG4105CSH Transporter EP552_09590 ENOG4108IJ0 Aspartate ammonia-lyase EP552_09605 ENOG4107YNJ LysR family Transcriptional regulator EP552_09615 ENOG4105CHU acetyl-coa acetyltransferase EP552_09620 ENOG4105CRW Short chain fatty acid transporter EP552_09625 ENOG4107QNJ CoA-transferase subunit B EP552_09635 ENOG4108M0I Transcriptional regulator EP552_09645 ENOG4105CY2 Citrate transporter EP552_09650 ENOG4105DTD Dehydrogenase EP552_09655 ENOG4105CF7 AraC family transcriptional regulator EP552_09660 ENOG4105D2S major facilitator superfamily EP552_09670 ENOG4105CHR reductase EP552_09695 ENOG4105F57 Anthranilate dioxygenase reductase EP552_09700 ENOG4108YS2 small subunit EP552_09705 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit EP552_09710 ENOG4105F4R Transcriptional regulator mode EP552_09715 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EP552_09720 ENOG4105E0C molybdate abc transporter EP552_09725 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) EP552_09730 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase EP552_09735 ENOG4105WQI isochorismatase EP552_09745 ENOG4107T31 5'-nucleotidase EP552_09780 ENOG4108IGT Dipeptidase EP552_09815 ENOG4107RZC phospholipase d EP552_09865 ENOG4105X0I Fimbrial EP552_09885 ENOG4105CJP fad dependent oxidoreductase EP552_09905 ENOG4105CT3 Monooxygenase EP552_09915 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EP552_09920 ENOG4105BZS acriflavin resistance protein EP552_09925 ENOG4105C1P efflux transporter, rnd family, mfp subunit EP552_09930 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EP552_09935 ENOG4105E0F Histidine kinase EP552_09940 ENOG4108821 RND type efflux pump EP552_09945 ENOG4108R6W Transcriptional regulator, ARAC family EP552_09960 ENOG4108BAS reductase EP552_10015 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) EP552_10055 ENOG4108UAJ Transcriptional regulator EP552_10135 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EP552_10155 ENOG4105E0A ABC, transporter EP552_10160 ENOG4105EHG Permease protein EP552_10170 ENOG4105DQ4 alcohol dehydrogenase EP552_10185 ENOG4105CF7 AraC family transcriptional regulator EP552_10190 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EP552_10200 ENOG4105EXW epimerase dehydratase EP552_10205 ENOG4105DDW LysR family Transcriptional regulator EP552_10215 ENOG4105C01 Dihydroxy-acid dehydratase EP552_10220 ENOG4105CZJ Aldehyde dehydrogenase EP552_10235 ENOG4105CW7 secretion protein, HlyD family EP552_10255 ENOG4105JSC dimethylmenaquinone methyltransferase EP552_10260 ENOG4108JQ1 Dehydrogenase EP552_10285 ENOG4106KR7 LysR family Transcriptional regulator EP552_10300 ENOG4105FDP GntR family transcriptional regulator EP552_10330 ENOG4105CKT filamentous hemagglutinin EP552_10335 ENOG4105D5K Hemolysin activator protein EP552_10350 ENOG4105CH2 amidohydrolase EP552_10360 ENOG4105CKD glutathione-regulated potassium-efflux system protein EP552_10365 ENOG4105D8V Glucose sorbosone dehydrogenase EP552_10370 ENOG4105EJC lysr family transcriptional regulator EP552_10375 ENOG4105CHJ isochorismatase hydrolase EP552_10395 ENOG4107Z3H Transcriptional regulator, TetR family EP552_10425 ENOG4105NAE bifunctional deaminase-reductase domain protein EP552_10435 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP552_10440 ENOG4105K56 Transcriptional regulator EP552_10465 ENOG4105CH6 catalase EP552_10480 ENOG4107RGH Aldehyde dehydrogenase EP552_10495 ENOG41062QD Membrane EP552_10505 ENOG4108JU7 Transcriptional regulator EP552_10510 ENOG4105CHR reductase EP552_10515 ENOG4105C1G acyl-Coa dehydrogenase EP552_10535 ENOG4105CZJ Aldehyde dehydrogenase EP552_10555 ENOG4107EJG GntR family transcriptional regulator EP552_10565 ENOG4108KB2 LysR family Transcriptional regulator EP552_10570 ENOG4105DTQ mandelate racemase muconate lactonizing EP552_10575 ENOG4105NN7 muconolactone delta-isomerase EP552_10585 ENOG4107QP7 CoA-transferase subunit A EP552_10590 ENOG4107QNJ CoA-transferase subunit B EP552_10595 ENOG4105CHU acetyl-coa acetyltransferase EP552_10600 ENOG4105F2Z 3-oxoadipate enol-lactonase EP552_10610 ENOG4105C26 Dehydrogenase EP552_10620 ENOG4105F11 amine oxidase EP552_10640 ENOG4105CHR reductase EP552_10650 ENOG4105FUY alpha subunit EP552_10670 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EP552_10680 ENOG4105DNH Major Facilitator EP552_10705 ENOG4105C1G acyl-Coa dehydrogenase EP552_10710 ENOG4108PTX LysR family Transcriptional regulator EP552_10715 ENOG4107HP6 Transcriptional regulator EP552_10730 ENOG4105MD1 YeeE YedE family protein EP552_10740 ENOG4105DZG Dehydrogenase EP552_10745 ENOG4105TW1 Carbohydrate-selective porin OprB EP552_10750 ENOG4106JPM 3-dehydroshikimate dehydratase EP552_10755 ENOG4105FF2 Type I DHQase EP552_10760 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha EP552_10765 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta EP552_10770 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EP552_10775 ENOG4105D2S major facilitator superfamily EP552_10780 ENOG4105F2Z 3-oxoadipate enol-lactonase EP552_10785 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase EP552_10790 ENOG4105CHU acetyl-coa acetyltransferase EP552_10795 ENOG4107QNJ CoA-transferase subunit B EP552_10800 ENOG4107QP7 CoA-transferase subunit A EP552_10810 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) EP552_10815 ENOG4107VMU Membrane EP552_10860 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP552_10875 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EP552_10885 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EP552_10890 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) EP552_10920 ENOG4105C7B Threonine dehydratase EP552_10930 ENOG4105CZN Potassium uptake protein EP552_10935 ENOG4105HDD phospholipase EP552_10945 ENOG4105E0K tonB-dependent siderophore receptor EP552_10960 ENOG4105PV3 Inner membrane protein yqiJ EP552_10965 ENOG4105F9F transposase EP552_10980 ENOG4105C4M (Ubiquinol oxidase) subunit I EP552_10985 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EP552_11005 ENOG41068P6 UPF0319 protein EP552_11015 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EP552_11040 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EP552_11045 ENOG4105C8Y Acetylornithine aminotransferase EP552_11050 ENOG4105M2J Glutaredoxin EP552_11060 ENOG4105CC0 LysR family Transcriptional regulator EP552_11065 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EP552_11070 ENOG4105CWM branched-chain amino acid transport system II carrier protein EP552_11095 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EP552_11100 ENOG4105DE4 1-phosphofructokinase EP552_11105 ENOG4105DM4 PTS System EP552_11125 ENOG4105BZU Histidine kinase EP552_11135 ENOG4105D8V Glucose sorbosone dehydrogenase EP552_11140 ENOG4108RAV Conserved protein EP552_11145 ENOG4105CHH sulfate transporter EP552_11160 ENOG4105C85 amino acid EP552_11170 ENOG4105F7P transcriptional regulator AsnC family EP552_11195 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 EP552_11200 ENOG4105VEJ Heat shock protein EP552_11210 ENOG4105Y3E Modulates RecA activity (By similarity) EP552_11225 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EP552_11250 ENOG4105DZP Membrane-associated zinc metalloprotease EP552_11260 ENOG4105KNE Phosphatidate cytidylyltransferase EP552_11265 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) EP552_11290 ENOG4105CUX Signal transduction histidine kinase EP552_11295 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EP552_11355 ENOG4105CMR udp-glucose 4-epimerase EP552_11360 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) EP552_11380 ENOG4105T38 integral membrane protein EP552_11385 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EP552_11395 ENOG4105CVM Molybdenum cofactor synthesis domain protein EP552_11400 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EP552_11415 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EP552_11435 ENOG4108IFG nitrite reductase, (NAD(P)H) EP552_11440 ENOG4107QZF nitrite reductase NADPH large subunit EP552_11450 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EP552_11475 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein EP552_11480 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EP552_11490 ENOG4105D8G Major Facilitator superfamily EP552_11500 ENOG4105DIJ Phosphoethanolamine transferase EP552_11655 ENOG4105F9F transposase EP552_11790 ENOG4105CBC glutamate synthase EP552_11820 ENOG4105C0A alcohol dehydrogenase EP552_11830 ENOG4105HSS phospholipase C EP552_11835 ENOG4107QMP dna polymerase iii subunits gamma and tau EP552_11860 ENOG4105CHR reductase EP552_11865 ENOG4105CHU acetyl-coa acetyltransferase EP552_11875 ENOG4105C5Q Transcriptional regulator EP552_11880 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EP552_11885 ENOG4108NIW Leucine export protein LeuE EP552_11890 ENOG4105EW9 transcriptional regulator AsnC family EP552_11895 ENOG4105DKK Benzoate EP552_11905 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EP552_11920 ENOG41081QV Universal stress protein EP552_11925 ENOG4105C5H ABC transporter EP552_11945 ENOG4105CNM Receptor EP552_11980 ENOG4105CUY Mechanosensitive ion channel EP552_11990 ENOG4105R8C Transcriptional regulator EP552_12005 ENOG4105EW9 transcriptional regulator AsnC family EP552_12010 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) EP552_12020 ENOG4105EMU Dehydrogenase EP552_12030 ENOG4105CD8 aminopeptidase N EP552_12050 ENOG4105F4I Transcriptional regulator EP552_12060 ENOG4107QUV Domain protein EP552_12065 ENOG4105C0A alcohol dehydrogenase EP552_12075 ENOG4107RR1 TRANSCRIPTIONal EP552_12085 ENOG4107R55 ethanolamine transporter EP552_12090 ENOG4105CPD ethanolamine ammonia-lyase EP552_12095 ENOG4107FQ9 ethanolamine ammonia-lyase EP552_12100 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EP552_12125 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) EP552_12135 ENOG4108RCM Nitroreductase EP552_12140 ENOG4108TZV Membrane EP552_12145 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EP552_12155 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) EP552_12160 ENOG4105K8N protein family UPF0079, ATPase EP552_12195 ENOG4105DZ2 Transcriptional regulator EP552_12210 ENOG4105F27 Major Facilitator EP552_12215 ENOG4105EYW Ion transport protein EP552_12225 ENOG4107QIJ Aconitate hydratase 2 EP552_12245 ENOG4105CFU surface antigen EP552_12250 ENOG4107S74 Lysophospholipid transporter LplT EP552_12265 ENOG4105CFQ glutamine synthetase EP552_12270 ENOG4105EEX Two component transcriptional regulator (Winged helix family EP552_12275 ENOG4105C08 Histidine kinase EP552_12285 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EP552_12290 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EP552_12310 ENOG4105D06 uba thif-type nad fad binding protein EP552_12315 ENOG4108MEJ flavin reductase domain protein EP552_12325 ENOG4105C1G acyl-Coa dehydrogenase EP552_12340 ENOG4105GVF (ABC) transporter EP552_12345 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EP552_12350 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EP552_12365 ENOG4105CC0 LysR family Transcriptional regulator EP552_12385 ENOG4105DEN Luciferase family EP552_12395 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD EP552_12400 ENOG4105CND Glycosyl transferase, family 2 EP552_12405 ENOG4107BJW polysaccharide deacetylase EP552_12430 ENOG4105E2S oxidase) subunit II EP552_12435 ENOG4105BZ9 Cytochrome C oxidase, subunit I EP552_12440 ENOG4105CCU oxidase (Subunit III) EP552_12445 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) EP552_12470 ENOG4105CDU Replicative dna helicase EP552_12475 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EP552_12525 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) EP552_12530 ENOG4105DC1 bifunctional purine biosynthesis protein purh EP552_12535 ENOG4105C12 Phosphoribosylglycinamide synthetase EP552_12545 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EP552_12550 ENOG4108UMI ABC transporter, permease EP552_12555 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EP552_12565 ENOG4105CK2 sodium dicarboxylate symporter EP552_12605 ENOG4105DY2 Paraquat-inducible protein b EP552_12610 ENOG4105F1S paraquat-inducible protein a EP552_12625 ENOG4105CEB Aspartate aminotransferase EP552_12650 ENOG4105CSH Transporter EP552_12700 ENOG4105JXH GntR family transcriptional regulator EP552_12710 ENOG4105D6U Sodium Glutamate Symporter EP552_12740 ENOG4105H4F exported protein EP552_12775 ENOG4105C26 Dehydrogenase EP552_12780 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EP552_12785 ENOG4105EVZ LysR family transcriptional regulator EP552_12810 ENOG4105D9P serine threonine protein kinase EP552_12835 ENOG4105VCC 30S ribosomal protein S21 EP552_12840 ENOG4105KTH gatB Yqey EP552_12845 ENOG4105ERG peptidase m48, ste24p EP552_12850 ENOG4105C5I Dehydrogenase EP552_12865 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase EP552_12900 ENOG41069NU Nitroreductase EP552_12910 ENOG4105C1J atp-dependent rna helicase EP552_12915 ENOG4105VEQ Cold shock protein EP552_12925 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EP552_12930 ENOG4105M08 Membrane EP552_12960 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) EP552_12965 ENOG4105CIN aminoacyl-histidine dipeptidase EP552_12975 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase EP552_12980 ENOG4105CQC Prephenate dehydratase EP552_12985 ENOG4105NIV Esterase EP552_12990 ENOG4105C1G acyl-Coa dehydrogenase EP552_12995 ENOG4105CK2 sodium dicarboxylate symporter EP552_13005 ENOG4107QYG anthranilate phosphoribosyltransferase EP552_13010 ENOG4105VUT cytoplasmic protein EP552_13015 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) EP552_13020 ENOG4105BZ4 penicillin-binding protein EP552_13030 ENOG4105M6F mutator MutT protein EP552_13040 ENOG4105DHQ Histidine kinase EP552_13045 ENOG4105XJC Two component transcriptional regulator (Winged helix family EP552_13055 ENOG4107QHF type ii secretion system protein e EP552_13065 ENOG4108R96 Methyltransferase, YaeB family EP552_13070 ENOG4105DP0 ferredoxin-NADP reductase EP552_13075 ENOG4105JAB phenazine biosynthesis protein, phzf family EP552_13080 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EP552_13085 ENOG4105CFP Peptidase U32 EP552_13090 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EP552_13100 ENOG4108JEH abc transporter atp-binding protein EP552_13105 ENOG4106YG3 ABC transporter EP552_13110 ENOG4105DSP amino acid AbC transporter EP552_13115 ENOG4105E89 ABC transporter EP552_13125 ENOG4105ENT Efflux transporter rnd family, mfp subunit EP552_13135 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EP552_13170 ENOG4105DA5 (ABC) transporter EP552_13175 ENOG4105E3A (ABC) transporter EP552_13190 ENOG4105CNI cell division protein FtsW EP552_13195 ENOG4105CVE Lytic murein transglycosylase EP552_13235 ENOG4105CE9 30S ribosomal protein S2 EP552_13240 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EP552_13250 ENOG4107RNU major facilitator superfamily MFS_1 EP552_13260 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) EP552_13265 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EP552_13270 ENOG4107QPN acyl-Coa dehydrogenase EP552_13285 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) EP552_13290 ENOG4105SYT Methylenetetrahydrofolate reductase EP552_13295 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EP552_13305 ENOG4105BZU Histidine kinase EP552_13310 ENOG4105C6K Malic enzyme EP552_13320 ENOG4105C0H protease EP552_13325 ENOG4107QNR UPF0135 protein EP552_13330 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EP552_13365 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) EP552_13375 ENOG4105C5F glutamine synthetase EP552_13380 ENOG4105DUX Transporter EP552_13390 ENOG4105DFP Integrase EP552_13475 ENOG4105UPP uncharacterized protein ydcA EP552_13775 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EP552_13800 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EP552_13810 ENOG4105D82 Glutamate dehydrogenase EP552_13815 ENOG4108R3D Electron transport complex EP552_13820 ENOG4105CSM endonuclease III EP552_13845 ENOG4105CJN penicillin-binding protein EP552_13850 ENOG4106H78 methyltransferase EP552_13865 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) EP552_13905 ENOG4107RET Isocitrate lyase EP552_13915 ENOG4105C37 (CBS) domain EP552_13925 ENOG4105D4T Citrate transporter EP552_13940 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) EP552_13955 ENOG4108MRJ EP552_13975 ENOG4105VCQ rubredoxin EP552_13980 ENOG4107QZF nitrite reductase NADPH large subunit EP552_13990 ENOG4105C5Q Transcriptional regulator EP552_14015 ENOG4107U91 Rhomboid family EP552_14020 ENOG4105CV6 ABC transporter, permease EP552_14025 ENOG4108I0Y (ABC) transporter EP552_14030 ENOG4108UJV acyl-CoA thioesterase i EP552_14050 ENOG4107RNH Outer membrane receptor FepA EP552_14065 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) EP552_14070 ENOG4105E6M Sulphatase-modifying factor protein EP552_14090 ENOG4105CJ3 phosphate transporter EP552_14095 ENOG4105C3R Methionine synthase EP552_14110 ENOG4105CSP Major Facilitator Superfamily EP552_14120 ENOG4108PZW LysR family Transcriptional regulator EP552_14135 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) EP552_14140 ENOG4105EU0 Major facilitator Superfamily EP552_14145 ENOG4108R6W Transcriptional regulator, ARAC family EP552_14150 ENOG4105CSV Glutaminase EP552_14155 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EP552_14160 ENOG4105CSH Transporter EP552_14170 ENOG4105C7K acetolactate synthase EP552_14185 ENOG4105CHR reductase EP552_14190 ENOG4108MXF Alpha Beta Hydrolase EP552_14200 ENOG4105DJB Major Facilitator Superfamily EP552_14205 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase EP552_14215 ENOG4105CHR reductase EP552_14235 ENOG41069M3 Transcriptional regulator EP552_14250 ENOG4106YT9 Enoyl-CoA hydratase EP552_14260 ENOG4105CND Glycosyl transferase, family 2 EP552_14265 ENOG4107BJW polysaccharide deacetylase EP552_14275 ENOG4108VWS Yaeq family EP552_14285 ENOG4105CKI cobalamin synthesis protein EP552_14305 ENOG4105C94 Transporter EP552_14310 ENOG4105C94 Transporter EP552_14315 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) EP552_14340 ENOG4107QK5 Homocysteine s-methyltransferase EP552_14345 ENOG4105D5Q Arginine ornithine antiporter EP552_14405 ENOG4108SF5 RNA Polymerase EP552_14415 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EP552_14420 ENOG4105C54 Major Facilitator superfamily EP552_14470 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) EP552_14475 ENOG4105C0R drug resistance transporter emrb qaca subfamily EP552_14480 ENOG4105CW7 secretion protein, HlyD family EP552_14485 ENOG4108VUY thioesterase Superfamily protein EP552_14490 ENOG4105D52 delta-aminolevulinic acid dehydratase EP552_14495 ENOG4105MWK D-amino acid dehydrogenase, small subunit EP552_14500 ENOG4105ECP epimerase EP552_14520 ENOG4107RH8 nuclease SbcCD subunit D EP552_14525 ENOG4105EYH Exonuclease EP552_14530 ENOG4105DFA alanine racemase domain protein EP552_14535 ENOG4105CZX twitching motility protein EP552_14540 ENOG4105CZX twitching motility protein EP552_14545 ENOG41090R7 Ferric uptake EP552_14575 ENOG4105E7A Glutamine amidotransferase EP552_14590 ENOG4107QKV phosphomannomutase EP552_14600 ENOG4105C4R Atp-dependent dna helicase EP552_14605 ENOG4108ZG0 Ompa motb domain protein EP552_14610 ENOG4106HNH Acyl-transferase EP552_14625 ENOG4107QMS site-determining protein EP552_14665 ENOG4105CNU cell division protein FtsK EP552_14670 ENOG4105C3M thioredoxin reductase EP552_14675 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) EP552_14685 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EP552_14730 ENOG4108YXA Membrane EP552_14735 ENOG4105EUB pirin domain protein EP552_14745 ENOG4105C4K Nad synthetase EP552_14760 ENOG4105E3J oxidoreductase EP552_14765 ENOG4105C26 Dehydrogenase EP552_14770 ENOG4105DVW rieske (2Fe-2S) EP552_14780 ENOG4105C94 Transporter EP552_14785 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EP552_14790 ENOG4105EJC lysr family transcriptional regulator EP552_14810 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EP552_14830 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EP552_14835 ENOG4105C34 Pseudouridine synthase EP552_14840 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane EP552_14845 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EP552_14860 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) EP552_14880 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EP552_14910 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EP552_14920 ENOG4105DWF phosphomethylpyrimidine kinase EP552_14925 ENOG4109066 lysm domain bon superfamily protein EP552_14935 ENOG4105CHR reductase EP552_14940 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EP552_14950 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein EP552_14955 ENOG4108BPE -transporting atpase EP552_14960 ENOG4107RTD sua5 ycio yrdc ywlc family protein EP552_14965 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) EP552_14970 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) EP552_14975 ENOG4105FE9 pseudouridine synthase EP552_14985 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EP552_14990 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) EP552_15000 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EP552_15005 ENOG4108K4C ec 3.1.3.12 EP552_15010 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase EP552_15015 ENOG4106UW1 Major Facilitator superfamily EP552_15035 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) EP552_15045 ENOG4105HF0 Membrane EP552_15060 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY EP552_15070 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) EP552_15130 ENOG4105D1F ATP-binding protein EP552_15140 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) EP552_15170 ENOG4105K6H D-cysteine desulfhydrase EP552_15175 ENOG4105CBX hi0933 family EP552_15200 ENOG4105DP0 ferredoxin-NADP reductase EP552_15205 ENOG4105DUM transcriptional regulator, lysR family EP552_15225 ENOG4105C8S subunit m EP552_15230 ENOG4105D65 subunit l EP552_15240 ENOG4107UFS subunit j EP552_15255 ENOG4108IEH NADH dehydrogenase subunit g EP552_15260 ENOG4107QIZ NADH dehydrogenase EP552_15265 ENOG4105GKE subunit e EP552_15285 ENOG4105BZU Histidine kinase EP552_15295 ENOG4105E0F Histidine kinase EP552_15300 ENOG4107EXC regulatoR EP552_15310 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EP552_15320 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EP552_15330 ENOG4105EB3 Histidine kinase EP552_15400 ENOG4105DZG Dehydrogenase EP552_15420 ENOG4105JAB phenazine biosynthesis protein, phzf family EP552_15435 ENOG4105F9F transposase EP552_15455 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) EP552_15460 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) EP552_15470 ENOG4105ETT transcriptional Regulator, LysR family EP552_15490 ENOG4105CH2 amidohydrolase EP552_15500 ENOG4106P55 Transcriptional regulator EP552_15520 ENOG4106P55 Transcriptional regulator EP552_15525 ENOG4107EFR Flavocytochrome c EP552_15535 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EP552_15540 ENOG4107RGD Major Facilitator superfamily EP552_15545 ENOG4105C1G acyl-Coa dehydrogenase EP552_15550 ENOG4105ETT transcriptional Regulator, LysR family EP552_15585 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) EP552_15590 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) EP552_15595 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EP552_15610 ENOG4105VR0 copper resistance EP552_15615 ENOG4105E3B Multicopper oxidase EP552_15625 ENOG4108HCJ Hydrolase EP552_15630 ENOG4105DJV ribulose-phosphate 3-epimerase EP552_15655 ENOG41072GX Peptidase M22 Glycoprotease EP552_15660 ENOG4108Z0R Transferase EP552_15720 ENOG4105CRQ synthase (Component I) EP552_15730 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) EP552_15735 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) EP552_15740 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) EP552_15810 ENOG4105K56 Transcriptional regulator EP552_15815 ENOG4108ZHJ Organic hydroperoxide resistance protein EP552_15820 ENOG4107QHF type ii secretion system protein e EP552_15840 ENOG4105C2M dna polymerase I EP552_15845 ENOG4108VIA integral membrane protein EP552_15850 ENOG4105II7 pyrroline-5-carboxylate reductase EP552_15855 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) EP552_15865 ENOG4105C9X ppx gppa phosphatase EP552_15875 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EP552_15895 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) EP552_15920 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) EP552_15935 ENOG4105W39 Membrane EP552_15940 ENOG4105CYM Glutathione S-transferase EP552_15960 ENOG4105CEY Amp-dependent synthetase and ligase EP552_15965 ENOG4105N42 UPF0307 protein EP552_15970 ENOG41080Z8 PHOSPHOCARRIER protein EP552_15990 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EP552_15995 ENOG4105DJ0 Poly(A) Polymerase EP552_16000 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein EP552_16005 ENOG4105DXN mazG family EP552_16015 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EP552_16030 ENOG4105C6T cysteine synthase EP552_16035 ENOG4105BZU Histidine kinase EP552_16040 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase EP552_16045 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EP552_16050 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EP552_16065 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EP552_16070 ENOG4105W8H transhydrogenase (subunit alpha EP552_16075 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EP552_16105 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EP552_16115 ENOG4107RSM transcriptional regulator EP552_16125 ENOG4105CUZ uba thif-type nad fad binding protein EP552_16135 ENOG4107QM5 aconitate hydratase EP552_16140 ENOG4105F8V Hydrolase, tatD family EP552_16155 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) EP552_16180 ENOG4105BZU Histidine kinase EP552_16190 ENOG4108ZP8 Acetolactate synthase small subunit EP552_16195 ENOG4105C7K acetolactate synthase EP552_16220 ENOG4105DJY efflux transporter, rnd family, mfp subunit EP552_16225 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EP552_16230 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EP552_16235 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH EP552_16245 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) EP552_16250 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) EP552_16260 ENOG4105VW4 glutaredoxin 3 EP552_16280 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EP552_16285 ENOG4105C2D reductase EP552_16295 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EP552_16325 ENOG4105C84 Histidine ammonia-lyase EP552_16340 ENOG4105CEY Amp-dependent synthetase and ligase EP552_16355 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) EP552_16375 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EP552_16395 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) EP552_16415 ENOG4105WVQ Fe-S assembly protein IscX EP552_16430 ENOG4105CN1 protease EP552_16445 ENOG4106HB6 Alpha beta hydrolase EP552_16455 ENOG4105C26 Dehydrogenase EP552_16460 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EP552_16465 ENOG4105C6Z Gluconate EP552_16470 ENOG4108UHU Aldolase EP552_16475 ENOG4105C01 Dihydroxy-acid dehydratase EP552_16480 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) EP552_16485 ENOG4108DNC Involved in acetate metabolism (By similarity) EP552_16490 ENOG4107GFK fumarate EP552_16510 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EP552_16520 ENOG4108ESX Receptor EP552_16530 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) EP552_16540 ENOG4105DWV Homoserine O-trans-acetylase EP552_16640 ENOG4105CIY formyltetrahydrofolate deformylase EP552_16650 ENOG4107RGH Aldehyde dehydrogenase EP552_16655 ENOG4105KDC 50s ribosomal protein l28 EP552_16660 ENOG4105W0E 50S ribosomal protein L33 EP552_16665 ENOG4105CKD glutathione-regulated potassium-efflux system protein EP552_16685 ENOG4105VFU Rna-binding protein EP552_16690 ENOG4105C4R Atp-dependent dna helicase EP552_16705 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EP552_16715 ENOG4105KVH Transcriptional regulator EP552_16725 ENOG41069P5 Protein slyX homolog EP552_16730 ENOG4105C5H ABC transporter EP552_16735 ENOG4105N14 lysine exporter protein LysE YggA EP552_16740 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase EP552_16750 ENOG4105CK2 sodium dicarboxylate symporter EP552_16805 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EP552_16830 ENOG4105DUM transcriptional regulator, lysR family EP552_16855 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase EP552_16870 ENOG4108W5M transcriptional regulator EP552_16890 ENOG4105D29 Helix-turn-helix type 11 domain protein EP552_16895 ENOG4107XGZ Hydrolase EP552_16900 ENOG4105EI2 Pseudouridine synthase EP552_16910 ENOG4105C03 ribonuclease EP552_16930 ENOG4105CBN LysR family transcriptional regulator EP552_16935 ENOG4105EMU Dehydrogenase EP552_16940 ENOG4105CSA Coproporphyrinogen iii oxidase EP552_16950 ENOG4107QI1 Mate efflux family protein EP552_16960 ENOG4107T8P acyl-Coa dehydrogenase EP552_17005 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) EP552_17010 ENOG4105C5X domain protein EP552_17025 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EP552_17035 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase EP552_17040 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) EP552_17045 ENOG4108JU5 Magnesium and cobalt efflux protein EP552_17050 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) EP552_17055 ENOG4108Z7R Chaperone CsaA EP552_17065 ENOG4108VAU general secretion pathway protein G EP552_17070 ENOG4105D7Q type ii secretion system EP552_17075 ENOG4105C25 Primosomal protein n' EP552_17080 ENOG4105CKD glutathione-regulated potassium-efflux system protein EP552_17085 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) EP552_17095 ENOG4105DVC DnaJ domain protein EP552_17100 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) EP552_17105 ENOG4107QUT magnesium and cobalt transport protein CorA EP552_17125 ENOG4107QYX exodeoxyribonuclease v alpha EP552_17130 ENOG4107QKA exodeoxyribonuclease V beta EP552_17135 ENOG4105DSY exodeoxyribonuclease V, gamma EP552_17145 ENOG4105CSR polyphosphate kinase 2 EP552_17155 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) EP552_17170 ENOG41061H0 Monooxygenase EP552_17175 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase EP552_17190 ENOG4105D65 subunit l EP552_17195 ENOG4108ZE9 Monovalent cation H antiporter subunit C EP552_17200 ENOG4107R4Z monovalent cation h antiporter subunit d EP552_17205 ENOG4105SC1 monovalent cation H antiporter subunit E EP552_17210 ENOG4105W4C monovalent cation H antiporter subunit F EP552_17215 ENOG4105KJM monovalent cation h antiporter subunit g EP552_17230 ENOG4105CHV Transcription elongation factor NusA EP552_17255 ENOG4107EJC Preprotein translocase subunit SecG EP552_17265 ENOG4107QHF type ii secretion system protein e EP552_17280 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EP552_17290 ENOG4105C2N RNA methyltransferase TrmH family group 3 EP552_17305 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EP552_17315 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) EP552_17345 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EP552_17350 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EP552_17420 ENOG4107ZXU DSBA oxidoreductase EP552_17435 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) EP552_17450 ENOG4105D3Y Na H antiporter EP552_17455 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EP552_17510 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EP552_17515 ENOG4105PM1 preprotein translocase subunit SecE EP552_17555 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EP552_17560 ENOG4105TV9 FHA Domain-Containing protein EP552_17565 ENOG4105GVR general secretion pathway protein D EP552_17580 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS EP552_17605 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) EP552_17610 ENOG4108NEV two component transcriptional regulator, LytTR family EP552_17615 ENOG4108HRK Histidine kinase EP552_17630 ENOG4108UTW Plays a role in the regulation of phosphate uptake EP552_17635 ENOG4105DFG type I secretion outer membrane protein EP552_17640 ENOG4108RNG Permease of the drug metabolite transporter EP552_17665 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EP552_17670 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EP552_17675 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) EP552_17680 ENOG4105CNI cell division protein FtsW EP552_17695 ENOG4105CE1 Ferrous iron transport protein b EP552_17705 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EP552_17710 ENOG4105T95 Thiol disulfide interChange protein EP552_17715 ENOG4105D6E homoserine dehydrogenase EP552_17725 ENOG41061WM D-Alanyl-D-Alanine EP552_17735 ENOG4107TUY Histidine kinase EP552_17740 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EP552_17745 ENOG4105CN1 protease EP552_17750 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) EP552_17755 ENOG4108K5H permease YjgP YjgQ family protein EP552_17795 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EP552_17805 ENOG4105BZU Histidine kinase EP552_17820 ENOG4105C0P Mg chelatase subunit ChlI EP552_17830 ENOG4108R0M Aminoglycoside EP552_17875 ENOG4105CHH sulfate transporter EP552_17920 ENOG4105C0P Mg chelatase subunit ChlI EP552_17925 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EP552_17935 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EP552_17950 ENOG4105EPF Outer membrane porin EP552_17955 ENOG4105F0N pyrophosphate phospho-hydrolase EP552_17970 ENOG4105CEY Amp-dependent synthetase and ligase EP552_17975 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EP552_17980 ENOG41079KZ Major Facilitator Superfamily EP552_17985 ENOG4105EN6 Membrane EP552_17990 ENOG4105K5B UPF0225 protein EP552_17995 ENOG4105EE5 Membrane protein terC EP552_18000 ENOG4108URH decarboxylase EP552_18005 ENOG4105C0R drug resistance transporter emrb qaca subfamily EP552_18015 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EP552_18030 ENOG4105CCT upf0313 protein EP552_18050 ENOG4105CS1 NAD(P)H quinone oxidoreductase EP552_18060 ENOG4105C6T cysteine synthase EP552_18095 ENOG4105Y7M Transcriptional regulator, TetR family EP552_18130 ENOG4105C79 DNA protecting protein DprA EP552_18145 ENOG4108IND Tetr family transcriptional regulator EP552_18150 ENOG4107RTG Major Facilitator superfamily EP552_18160 ENOG4108V06 Glutathione peroxidase EP552_18170 ENOG41090VV Protein of unknown function (DUF2846) EP552_18205 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) EP552_18230 ENOG4105FDK ABC transporter EP552_18235 ENOG4105FAV ABC, transporter EP552_18245 ENOG4105EZR dyp-type peroxidase family protein EP552_18250 ENOG4107R1I NAD-dependent malic enzyme EP552_18275 ENOG4105EUB pirin domain protein EP552_18310 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EP552_18315 ENOG4106MP8 UPF0754 membrane protein EP552_18320 ENOG4108VBZ doxx family EP552_18325 ENOG4105DQR SNARE associated Golgi EP552_18340 ENOG4107QJE Chromosome Partitioning Protein EP552_18350 ENOG4107PSF BolA-like protein EP552_18390 ENOG4105C1G acyl-Coa dehydrogenase EP552_18415 ENOG4105CSH Transporter EP552_18420 ENOG4105E39 Enoyl-CoA hydratase EP552_18425 ENOG4105E39 Enoyl-CoA hydratase EP552_18430 ENOG4105C1G acyl-Coa dehydrogenase EP552_18440 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EP552_18445 ENOG4105C26 Dehydrogenase EP552_18455 ENOG4105C85 amino acid EP552_18460 ENOG4105C85 amino acid EP552_18465 ENOG4105M4H endoribonuclease L-psp EP552_18480 ENOG4105EW9 transcriptional regulator AsnC family EP552_18505 ENOG4105D3G Pseudouridine synthase EP552_18555 ENOG4108I0Z Aconitate hydratase EP552_18560 ENOG4105BZN citrate synthase EP552_18565 ENOG4105CR4 methylisocitrate lyase EP552_18570 ENOG4105DRR Transcriptional regulator, GntR family EP552_18580 ENOG4105CGF Aromatic amino acid aminotransferase EP552_18585 ENOG4105CXG d-lactate dehydrogenase EP552_18595 ENOG41073TP transcriptional regulator EP552_18600 ENOG4105DAA L-lactate EP552_18605 ENOG4107QKV phosphomannomutase EP552_18615 ENOG4105CMR udp-glucose 4-epimerase EP552_18625 ENOG4105C6Y Udp-glucose 6-dehydrogenase EP552_18630 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EP552_18635 ENOG4105D3Q Sugar transferase EP552_18640 ENOG4108RYC glycosyltransferase EP552_18645 ENOG4105CG5 Glycosyl transferase (Group 1 EP552_18675 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EP552_18680 ENOG4105J5G Transferase hexapeptide repeat containing protein EP552_18685 ENOG4107R5Z Oxidoreductase domain protein EP552_18690 ENOG4107QQG Dehydrogenase EP552_18695 ENOG4105DAY polysaccharide export protein EP552_18705 ENOG4105D75 Capsular exopolysaccharide family EP552_18710 ENOG4108V1T peptidylprolyl cis-trans isomerase EP552_18715 ENOG4108V1T peptidylprolyl cis-trans isomerase EP552_18720 ENOG4105CJR Integral membrane protein (MviN EP552_18725 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EP552_18730 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EP552_18740 ENOG4105HSS phospholipase C EP552_18765 ENOG41062JF Transcriptional regulator EP552_18780 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EP552_18785 ENOG4105UBK short-chain dehydrogenase reductase EP552_18800 ENOG4107QZM n-acetylglutamate synthase EP552_18805 ENOG4105GVF (ABC) transporter EP552_18810 ENOG4105GVF (ABC) transporter EP552_18815 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EP552_18820 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EP552_18825 ENOG4108VM9 ABC, transporter EP552_18830 ENOG4108R86 Transcriptional regulator EP552_18835 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) EP552_18845 ENOG4105DTN riboflavin biosynthesis protein ribF EP552_18850 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) EP552_18860 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase EP552_18900 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EP552_18955 ENOG4105CVE Lytic murein transglycosylase EP552_18960 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EP552_18965 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EP552_18980 ENOG4105DFU Cell wall formation (By similarity) EP552_18990 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EP552_18995 ENOG4105DU1 integral membrane protein, terc EP552_19005 ENOG4106032 Glutathionylspermidine synthase EP552_19015 ENOG4107QUY Guanine deaminase EP552_19020 ENOG4108UGV hypoxanthine phosphoribosyltransferase EP552_19030 ENOG4105T95 Thiol disulfide interChange protein EP552_19035 ENOG4105PGM cation diffusion facilitator family transporter EP552_19050 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EP552_19065 ENOG4105VG0 50S ribosomal protein l34 EP552_19120 ENOG4105KK6 nuclease EP552_19130 ENOG4108HWY Beta-lactamase EP552_19140 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS EP552_19200 ENOG4105FA0 parb-like partition protein EP552_19220 ENOG4105CDW Resistance protein EP552_19325 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) EP552_19395 ENOG4105F9F transposase EP552_19405 ENOG4105F9F transposase EP552_19435 ENOG4105K5T PilT protein EP552_19470 ENOG4105T95 Thiol disulfide interChange protein EP552_19550 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EP552_19595 ENOG4105UGU tonB-dependent Receptor EP552_19605 ENOG4105F9F transposase