locus-tag class description EQH48_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EQH48_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EQH48_00030 ENOG4105DQR SNARE associated Golgi EQH48_00035 ENOG4105C5H ABC transporter EQH48_00040 ENOG4108821 RND type efflux pump EQH48_00045 ENOG4108821 RND type efflux pump EQH48_00050 ENOG4108821 RND type efflux pump EQH48_00060 ENOG4105D74 hydrolase EQH48_00065 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) EQH48_00070 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) EQH48_00115 ENOG4105C8J )-transporter EQH48_00125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B EQH48_00150 ENOG4108W5M transcriptional regulator EQH48_00155 ENOG4105C2W permease EQH48_00165 ENOG4108IG5 Transcriptional regulator EQH48_00170 ENOG4105DJY efflux transporter, rnd family, mfp subunit EQH48_00205 ENOG4105F27 Major Facilitator EQH48_00210 ENOG4105CV8 reductase EQH48_00215 ENOG4105HEI LysR family (Transcriptional regulator EQH48_00235 ENOG4105DQ4 alcohol dehydrogenase EQH48_00240 ENOG4108R3E Dna-3-methyladenine glycosylase i EQH48_00255 ENOG4105CEN a g-specific adenine glycosylase EQH48_00275 ENOG4108ZZ3 UPF0260 protein EQH48_00285 ENOG4105D1H recombination factor protein RarA EQH48_00290 ENOG4105S64 Formate nitrite transporter EQH48_00310 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EQH48_00315 ENOG4108RWI nicotinamidase EQH48_00320 ENOG4105C09 Bile acid EQH48_00325 ENOG4107QI1 Mate efflux family protein EQH48_00330 ENOG4105EWC Purine nucleoside phosphorylase EQH48_00350 ENOG4108RXX maleylacetoacetate isomerase EQH48_00360 ENOG4105C85 amino acid EQH48_00370 ENOG4105CKI cobalamin synthesis protein EQH48_00380 ENOG4105CZE histidine utilization repressor EQH48_00385 ENOG41090B9 response to stress EQH48_00400 ENOG4105C85 amino acid EQH48_00410 ENOG41088SP formiminoglutamate hydrolase EQH48_00425 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EQH48_00470 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EQH48_00480 ENOG4108ZAI phosphatidylglycerophosphatase a EQH48_00485 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) EQH48_00500 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EQH48_00550 ENOG4105KHC sulfurtransferase EQH48_00575 ENOG4105BZU Histidine kinase EQH48_00580 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EQH48_00595 ENOG4107QJQ Mate efflux family protein EQH48_00600 ENOG4105CHM Aminotransferase EQH48_00605 ENOG4106BRA Membrane EQH48_00620 ENOG4105D9M gamma-glutamylcysteine synthetase EQH48_00630 ENOG4105CS6 Rhs element vgr protein EQH48_00640 ENOG4106I9N Immunoglobulin G binding protein A EQH48_00670 ENOG4105IPS esterase EQH48_00675 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EQH48_00680 ENOG4105EWI Short-chain dehydrogenase reductase Sdr EQH48_00685 ENOG4108Z2U ureidoglycolate hydrolase EQH48_00695 ENOG41061H0 Monooxygenase EQH48_00710 ENOG41084YZ Hydrolase EQH48_00740 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) EQH48_00745 ENOG4105BZU Histidine kinase EQH48_00760 ENOG4105KUZ arsenate reductase EQH48_00765 ENOG4105CGK Exodeoxyribonuclease III EQH48_00785 ENOG4105D7Z glutathione synthase EQH48_00805 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) EQH48_00810 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EQH48_00815 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EQH48_00830 ENOG41063SB peptidase EQH48_00835 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) EQH48_00840 ENOG4107QSN dihydrolipoamide acetyltransferase EQH48_00855 ENOG4105E0K tonB-dependent siderophore receptor EQH48_00870 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EQH48_00885 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EQH48_00905 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EQH48_00910 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase EQH48_00920 ENOG4105D64 Mechanosensitive ion channel EQH48_00930 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EQH48_00935 ENOG4108W2Y isochorismatase EQH48_00945 ENOG4105FBW Monooxygenase EQH48_00950 ENOG4108UZX fmn reductase EQH48_00965 ENOG4105BZU Histidine kinase EQH48_00970 ENOG41062QD Membrane EQH48_00975 ENOG4107QN1 sodium solute EQH48_00985 ENOG4105C94 Transporter EQH48_00995 ENOG4105BZU Histidine kinase EQH48_01030 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EQH48_01035 ENOG4108WUH Transcriptional regulator, TetR family EQH48_01050 ENOG4105RA2 Membrane EQH48_01055 ENOG4105DWF phosphomethylpyrimidine kinase EQH48_01065 ENOG4107RDB Major Facilitator EQH48_01070 ENOG4108UUM single-stranded DNA-binding protein EQH48_01080 ENOG4108UMN azlc family EQH48_01090 ENOG4105C85 amino acid EQH48_01100 ENOG4108JPW Aminotransferase EQH48_01105 ENOG4105C26 Dehydrogenase EQH48_01115 ENOG4105CHJ isochorismatase hydrolase EQH48_01120 ENOG4105EUB pirin domain protein EQH48_01165 ENOG4105D94 Major Facilitator Superfamily EQH48_01170 ENOG4106NZI LysR family Transcriptional regulator EQH48_01190 ENOG4105CPC Aldo Keto reductase EQH48_01195 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) EQH48_01225 ENOG4105KVH Transcriptional regulator EQH48_01235 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein EQH48_01300 ENOG4105CUV Homoserine Kinase EQH48_01315 ENOG41061CK Antibiotic biosynthesis monooxygenase EQH48_01345 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) EQH48_01375 ENOG4105CYC Transferase EQH48_01385 ENOG4105E0F Histidine kinase EQH48_01390 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EQH48_01400 ENOG4105CHH sulfate transporter EQH48_01405 ENOG4105PDP Short chain dehydrogenase EQH48_01415 ENOG4105C5H ABC transporter EQH48_01500 ENOG4108IQI permease EQH48_01525 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EQH48_01540 ENOG4105CJN penicillin-binding protein EQH48_01545 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EQH48_01550 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) EQH48_01565 ENOG4105DHI Methyltransferase EQH48_01570 ENOG4108JQC penicillin-binding protein 1A EQH48_01595 ENOG4105E4G Type IV pilus EQH48_01615 ENOG4105CBC glutamate synthase EQH48_01620 ENOG4105BZ8 glutamate synthase EQH48_01630 ENOG4108V0P LemA family EQH48_01635 ENOG4105HA9 of methanol dehydrogenase type EQH48_01650 ENOG4108YSG O-Antigen polymerase EQH48_01655 ENOG4108UQY Iron-storage protein EQH48_01665 ENOG4105KME endoribonuclease L-psp EQH48_01670 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EQH48_01685 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) EQH48_01735 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) EQH48_01750 ENOG4107IFA Lipase (EC 3.1.1.3) EQH48_01755 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) EQH48_01760 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) EQH48_01785 ENOG4108JQ1 Dehydrogenase EQH48_01790 ENOG4105CQB FAD linked oxidase domain protein EQH48_01800 ENOG4105VRH Antibiotic biosynthesis monooxygenase EQH48_01805 ENOG4105NF4 modulator of drug activity EQH48_01815 ENOG4107QF7 multi-drug EQH48_01820 ENOG4105EM2 membrane EQH48_01825 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EQH48_01830 ENOG4105IPI Membrane EQH48_01835 ENOG4107SKI cobyrinic Acid a,c-diamide synthase EQH48_01865 ENOG4108IQI permease EQH48_01870 ENOG4105D82 Glutamate dehydrogenase EQH48_01875 ENOG4105C8Y Acetylornithine aminotransferase EQH48_01885 ENOG4105C26 Dehydrogenase EQH48_01910 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin EQH48_01975 ENOG4105W87 Cbs domain EQH48_01980 ENOG41067S9 phage shock protein C, PspC EQH48_01990 ENOG4105CSU acyl-Coa dehydrogenase EQH48_02005 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) EQH48_02020 ENOG4105ECY inositol monophosphatase EQH48_02025 ENOG4105C1J atp-dependent rna helicase EQH48_02035 ENOG4105DHJ ABC, transporter EQH48_02040 ENOG4105CY3 ABC transporter, permease EQH48_02050 ENOG4105E3I toluene tolerance EQH48_02060 ENOG4105D7N magnesium and cobalt transport protein CorA EQH48_02065 ENOG4108URH decarboxylase EQH48_02075 ENOG4105MJ2 Competence protein EQH48_02080 ENOG4105CB5 ATP-dependent DNA helicase recG EQH48_02100 ENOG4105C29 acyl-CoA thioesterase EQH48_02105 ENOG4105CK2 sodium dicarboxylate symporter EQH48_02120 ENOG4105KPV Transcriptional regulator EQH48_02130 ENOG4105D7A ATP-binding protein EQH48_02135 ENOG4105C28 cystathionine EQH48_02140 ENOG41089BK Glutamine amido-transferase EQH48_02250 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EQH48_02255 ENOG41067V7 50S ribosomal protein L36 EQH48_02265 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) EQH48_02290 ENOG4105C1G acyl-Coa dehydrogenase EQH48_02325 ENOG4105VKU nucleicacid-binding protein EQH48_02330 ENOG4105DGW oligopeptidase A EQH48_02335 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EQH48_02380 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase EQH48_02385 ENOG4108K2B transcriptional regulator EQH48_02395 ENOG4107S2Z UPF0761 membrane protein EQH48_02400 ENOG4105CS1 NAD(P)H quinone oxidoreductase EQH48_02430 ENOG4105C9A Phoh family EQH48_02440 ENOG4105E4C Lytic transglycosylase catalytic EQH48_02470 ENOG4105D6S protein involved in catabolism of external DNA EQH48_02475 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EQH48_02520 ENOG4105C1G acyl-Coa dehydrogenase EQH48_02525 ENOG4108RZE Tetr family transcriptional regulator EQH48_02540 ENOG4107QX3 carboxylase EQH48_02545 ENOG4105C1G acyl-Coa dehydrogenase EQH48_02565 ENOG4105KB2 stringent starvation protein b EQH48_02570 ENOG4107MKT Stringent starvation protein a EQH48_02575 ENOG4108UJD 30S ribosomal protein S9 EQH48_02585 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EQH48_02590 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) EQH48_02595 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) EQH48_02615 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EQH48_02625 ENOG4107RZC phospholipase d EQH48_02635 ENOG4105UYK outer membrane protein a EQH48_02645 ENOG4108KHX Diguanylate cyclase EQH48_02680 ENOG4107QN2 dihydrolipoyl dehydrogenase EQH48_02690 ENOG4107QPB Beta-lactamase domain protein EQH48_02695 ENOG4107U2T alpha beta EQH48_02705 ENOG4105NAU thioesterase Superfamily protein EQH48_02735 ENOG4105K9H YciI-like protein EQH48_02745 ENOG4105DB7 PHP domain protein EQH48_02750 ENOG4105FFC UPF0187 protein EQH48_02760 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EQH48_02765 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EQH48_02770 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EQH48_02775 ENOG4105VIE preprotein translocase, subunit YajC EQH48_02805 ENOG4105BZU Histidine kinase EQH48_02810 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) EQH48_02815 ENOG4105CM2 brancheD-chain amino acid aminotransferase EQH48_02830 ENOG4107BJW polysaccharide deacetylase EQH48_02840 ENOG4108PQP glycosyl transferase group 1 EQH48_02885 ENOG4105UGU tonB-dependent Receptor EQH48_02905 ENOG4108VY7 phosphate-starvation-inducible protein PsiE EQH48_02910 ENOG4105CSU acyl-Coa dehydrogenase EQH48_02915 ENOG4105CSU acyl-Coa dehydrogenase EQH48_02925 ENOG4105EB3 Histidine kinase EQH48_02930 ENOG4105E3W Two component transcriptional regulator (Winged helix family EQH48_02935 ENOG4105CNG UPF0061 protein EQH48_02955 ENOG4108WBT adenosyltransferase EQH48_02970 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EQH48_03005 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EQH48_03025 ENOG4105D3R alkyl hydroperoxide reductase EQH48_03040 ENOG4105CSH Transporter EQH48_03045 ENOG4108UT2 hemolysin iii EQH48_03075 ENOG4105CHU acetyl-coa acetyltransferase EQH48_03080 ENOG4108R6W Transcriptional regulator, ARAC family EQH48_03090 ENOG4105TW1 Carbohydrate-selective porin OprB EQH48_03095 ENOG4105DZG Dehydrogenase EQH48_03100 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EQH48_03110 ENOG410814C multidrug resistance protein EQH48_03120 ENOG4105CHU acetyl-coa acetyltransferase EQH48_03130 ENOG4108WHA ompa motb domain protein EQH48_03135 ENOG4105E0Y RtcB Protein EQH48_03140 ENOG4108IQI permease EQH48_03150 ENOG4105C2W permease EQH48_03170 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EQH48_03180 ENOG4108VX5 3-methyladenine DNA glycosylase EQH48_03190 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EQH48_03205 ENOG4105T95 Thiol disulfide interChange protein EQH48_03210 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) EQH48_03220 ENOG4105K78 MarR family Transcriptional regulator EQH48_03225 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EQH48_03230 ENOG4105KWI UPF0339 protein EQH48_03255 ENOG4108UNF response regulator EQH48_03260 ENOG4105M3Z response regulator EQH48_03265 ENOG4108ZGA chew protein EQH48_03270 ENOG4105C8Q Methyl-accepting chemotaxis EQH48_03290 ENOG4106HKS Entericidin EcnA/B family EQH48_03300 ENOG4105WD1 Membrane EQH48_03305 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EQH48_03345 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) EQH48_03355 ENOG4105EM2 membrane EQH48_03360 ENOG4105C2C drug resistance transporter, Bcr CflA EQH48_03380 ENOG4105BZG amino acid carrier protein EQH48_03385 ENOG4105D78 K07001 NTE family protein EQH48_03390 ENOG4105C7B Threonine dehydratase EQH48_03425 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EQH48_03435 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EQH48_03440 ENOG4105DFF Rod shape-determining protein mreb EQH48_03445 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EQH48_03450 ENOG4105VQ7 Rod shape-determining protein MreD EQH48_03455 ENOG4108Z03 MAF-like protein EQH48_03460 ENOG4105C03 ribonuclease EQH48_03470 ENOG4105D8T Acyltransferase EQH48_03480 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein EQH48_03490 ENOG4108X0B nad(p)h dehydrogenase (quinone) EQH48_03515 ENOG4105CF7 AraC family transcriptional regulator EQH48_03535 ENOG4105C85 amino acid EQH48_03540 ENOG4105C7F AcnD-accessory protein PrpF EQH48_03545 ENOG4105CTB Polyprenyl synthetase EQH48_03550 ENOG4105MSB protein, conserved in bacteria EQH48_03565 ENOG4105D78 K07001 NTE family protein EQH48_03585 ENOG4105DIJ Phosphoethanolamine transferase EQH48_03590 ENOG4105XJC Two component transcriptional regulator (Winged helix family EQH48_03595 ENOG4105DHQ Histidine kinase EQH48_03615 ENOG4108M0I Transcriptional regulator EQH48_03635 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) EQH48_03655 ENOG4105K8R UPF0145 protein EQH48_03660 ENOG4105K8R UPF0145 protein EQH48_03665 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EQH48_03670 ENOG4105BZS acriflavin resistance protein EQH48_03675 ENOG4105C1P efflux transporter, rnd family, mfp subunit EQH48_03680 ENOG410841Q phosphoesterase PA-phosphatase related protein EQH48_03710 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) EQH48_03725 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EQH48_03730 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EQH48_03735 ENOG4105KVH Transcriptional regulator EQH48_03745 ENOG4105CUB amino acid EQH48_03760 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) EQH48_03765 ENOG41084BA UPF0250 protein EQH48_03770 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EQH48_03805 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit EQH48_03810 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein EQH48_03820 ENOG4105E33 succinate dehydrogenase EQH48_03835 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 EQH48_03840 ENOG4105C7S Dehydrogenase EQH48_03845 ENOG4107QN2 dihydrolipoyl dehydrogenase EQH48_03855 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EQH48_03865 ENOG4105CKW Inner membrane protein yedI EQH48_03870 ENOG4105CGZ zinc metallopeptidase EQH48_03875 ENOG4105EEQ Na H antiporter EQH48_03890 ENOG4105PNM synthesis protein EQH48_03905 ENOG41080TK Universal stress protein EQH48_03920 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain EQH48_03925 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain EQH48_03940 ENOG4105HBR Rna-binding protein EQH48_03950 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EQH48_03955 ENOG4105EEI dihydropteroate synthase EQH48_04005 ENOG4105CSH Transporter EQH48_04010 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EQH48_04015 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EQH48_04030 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EQH48_04050 ENOG41080IJ Diacylglycerol kinase EQH48_04060 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase EQH48_04065 ENOG4105BZS acriflavin resistance protein EQH48_04080 ENOG4105E4C Lytic transglycosylase catalytic EQH48_04105 ENOG4108RRZ Transcription elongation factor GreB EQH48_04120 ENOG4105CEY Amp-dependent synthetase and ligase EQH48_04165 ENOG4105BZW Glycerate kinase EQH48_04170 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit EQH48_04175 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EQH48_04190 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) EQH48_04200 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EQH48_04205 ENOG4105C85 amino acid EQH48_04215 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EQH48_04225 ENOG4105N14 lysine exporter protein LysE YggA EQH48_04230 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EQH48_04235 ENOG4105BZJ Electron transfer flavoprotein EQH48_04240 ENOG4105C10 Electron transfer flavoprotein EQH48_04245 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EQH48_04280 ENOG4107KET secretion protein, HlyD family EQH48_04310 ENOG4105D60 lipoprotein releasing system transmembrane protein EQH48_04315 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) EQH48_04320 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EQH48_04330 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) EQH48_04335 ENOG4107R6F Alpha Beta Hydrolase Fold protein EQH48_04340 ENOG4108V3E phosphoribosylglycinamide formyltransferase EQH48_04350 ENOG4105C02 permease EQH48_04400 ENOG4105KCK Peptidoglycan-associated lipoprotein EQH48_04405 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) EQH48_04415 ENOG4105M8F Biopolymer transport protein exbD tolR EQH48_04420 ENOG4105E02 MotA TolQ exbB proton channel EQH48_04425 ENOG4107YD3 Thioesterase EQH48_04430 ENOG4105CH2 amidohydrolase EQH48_04450 ENOG4108ETH Formylglycinamide ribotide synthetase EQH48_04455 ENOG4105C2C drug resistance transporter, Bcr CflA EQH48_04460 ENOG4105EGD dinuclear metal center protein, YbgI family EQH48_04465 ENOG4108UKI Enoyl-CoA hydratase EQH48_04480 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EQH48_04495 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) EQH48_04500 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EQH48_04515 ENOG4107R11 Transcriptional regulator EQH48_04520 ENOG4108IJ6 ABC transporter EQH48_04530 ENOG4108I5D sulfate abc transporter EQH48_04540 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EQH48_04545 ENOG4105YAZ 4-amino-4-deoxychorismate lyase EQH48_04550 ENOG4105HHA aminodeoxychorismate lyase EQH48_04565 ENOG4108IYU L-aspartate oxidase EQH48_04570 ENOG4105C0H protease EQH48_04585 ENOG4105C3F Signal peptidase i EQH48_04600 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) EQH48_04610 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) EQH48_04615 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) EQH48_04620 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase EQH48_04625 ENOG4105EMU Dehydrogenase EQH48_04680 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EQH48_04690 ENOG4105DTR rard protein EQH48_04725 ENOG4107QS8 (LipO)protein EQH48_04730 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EQH48_04735 ENOG4105EA8 2-Nitropropane dioxygenase EQH48_04765 ENOG4107R8N Glycosyl transferase, family 2 EQH48_04780 ENOG4105CVP deoxyribo-dipyrimidine photolyase EQH48_04785 ENOG4108YZY peptidylprolyl cis-trans isomerase EQH48_04790 ENOG4105CEP NADH dehydrogenase EQH48_04815 ENOG4105E9K Isocitrate dehydrogenase EQH48_04820 ENOG4108R99 pseudouridine synthase EQH48_04845 ENOG4105CBP Major Facilitator EQH48_04850 ENOG4105EGI Transcriptional regulator EQH48_04855 ENOG4108ETY sodium dicarboxylate symporter EQH48_04860 ENOG4105JAB phenazine biosynthesis protein, phzf family EQH48_04890 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) EQH48_04905 ENOG4105D3G Pseudouridine synthase EQH48_04910 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) EQH48_04925 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EQH48_04950 ENOG4108JPW Aminotransferase EQH48_04955 ENOG4105DY8 decarboxylase EQH48_04965 ENOG4105F7P transcriptional regulator AsnC family EQH48_04970 ENOG4107RA9 decarboxylase EQH48_04975 ENOG4105C85 amino acid EQH48_04980 ENOG4105CVA phosphate EQH48_04985 ENOG4105C8U phosphate abc transporter EQH48_04995 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EQH48_05000 ENOG4105ERU peptidase EQH48_05015 ENOG4107QTF adenylosuccinate lyase EQH48_05035 ENOG4108Z0R Transferase EQH48_05040 ENOG4105DZ1 carboxypeptidase EQH48_05060 ENOG4108K5P (LipO)protein EQH48_05065 ENOG4105EJC lysr family transcriptional regulator EQH48_05070 ENOG4105DAN ATP-dependent protease EQH48_05085 ENOG4105DHU Bile acid EQH48_05105 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EQH48_05115 ENOG4105D22 carbon starvation protein EQH48_05120 ENOG4105VCD cytoplasmic protein EQH48_05155 ENOG4108K8K Transcriptional regulator EQH48_05170 ENOG4105C26 Dehydrogenase EQH48_05190 ENOG4105C85 amino acid EQH48_05195 ENOG4105ETT transcriptional Regulator, LysR family EQH48_05200 ENOG4105C94 Transporter EQH48_05205 ENOG4105C94 Transporter EQH48_05220 ENOG4105C26 Dehydrogenase EQH48_05225 ENOG4107QZF nitrite reductase NADPH large subunit EQH48_05230 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) EQH48_05260 ENOG41060M8 Pfam:PhdYeFM EQH48_05265 ENOG4107QNK )-transporter EQH48_05270 ENOG4107WEA mandelate racemase muconate lactonizing EQH48_05280 ENOG4105J7D transcriptional regulator EQH48_05300 ENOG4105C2I pirin domain protein EQH48_05310 ENOG4105WWK YheO domain protein EQH48_05325 ENOG4105CEY Amp-dependent synthetase and ligase EQH48_05340 ENOG4108IPW abc transporter atp-binding protein EQH48_05370 ENOG4105C0W non-ribosomal peptide synthetase EQH48_05375 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EQH48_05380 ENOG4105WQI isochorismatase EQH48_05395 ENOG4105BZ1 (ABC) transporter EQH48_05415 ENOG4105E4F Isochorismate synthase EQH48_05430 ENOG4105NX3 Membrane EQH48_05445 ENOG41066YJ Beta-lactamase EQH48_05455 ENOG4105EUJ GTP cyclohydrolase i EQH48_05465 ENOG4105C7W Xanthine dehydrogenase EQH48_05495 ENOG4105CD8 aminopeptidase N EQH48_05500 ENOG4105DDQ anthranilate synthase EQH48_05565 ENOG41067QW Transcriptional regulator EQH48_05815 ENOG4105DR5 peptidase EQH48_05860 ENOG4105DIJ Phosphoethanolamine transferase EQH48_05895 ENOG4107RAQ aminopeptidase EQH48_05900 ENOG4105D0A hydroxylase EQH48_05905 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EQH48_05925 ENOG4108ZUB Lysine exporter protein (Lyse ygga) EQH48_05930 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) EQH48_05940 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EQH48_05950 ENOG4105W4M Transport-associated protein EQH48_05960 ENOG4105E09 nadh pyrophosphatase EQH48_05970 ENOG4107RZZ dna polymerase iii epsilon subunit EQH48_05975 ENOG4105E9H Lytic Murein transglycosylase EQH48_05975 ENOG4105E9H Lytic Murein transglycosylase EQH48_05985 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EQH48_05990 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EQH48_05995 ENOG4108JQ5 ABC transporter EQH48_06015 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) EQH48_06035 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EQH48_06050 ENOG4108M3P Membrane EQH48_06055 ENOG4105D01 (LipO)protein EQH48_06110 ENOG4105F95 Monooxygenase EQH48_06120 ENOG4105C7N Xanthine uracil vitamin C permease EQH48_06125 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) EQH48_06130 ENOG4105CPW cytochrome b561 EQH48_06140 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) EQH48_06150 ENOG4105CFH Aspartokinase EQH48_06160 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EQH48_06170 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis EQH48_06185 ENOG4105CPC Aldo Keto reductase EQH48_06190 ENOG4107RYR Transcriptional regulator, Crp Fnr family EQH48_06195 ENOG4108UKZ OsmC family EQH48_06210 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EQH48_06240 ENOG4105CD3 dihydroorotase EQH48_06245 ENOG4108ZG0 Ompa motb domain protein EQH48_06255 ENOG4108TGY Glutathione S-transferase EQH48_06260 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) EQH48_06270 ENOG4108K3A Glutathione S-transferase EQH48_06280 ENOG4108JU3 Alkyl hydroperoxide reductase EQH48_06290 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) EQH48_06300 ENOG4105D3R alkyl hydroperoxide reductase EQH48_06305 ENOG4105CQ7 ATP-dependent helicase EQH48_06320 ENOG4105D2S major facilitator superfamily EQH48_06325 ENOG4105DKK Benzoate EQH48_06330 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase EQH48_06335 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein EQH48_06340 ENOG4108UKV benzoate 1,2-dioxygenase EQH48_06345 ENOG4105FUY alpha subunit EQH48_06350 ENOG4108KB2 LysR family Transcriptional regulator EQH48_06415 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) EQH48_06450 ENOG410829K Lysine exporter protein (Lyse ygga) EQH48_06455 ENOG4105VEQ Cold shock protein EQH48_06465 ENOG4105II7 pyrroline-5-carboxylate reductase EQH48_06485 ENOG4105F9F transposase EQH48_06500 ENOG4107YPT transcriptional regulator EQH48_06520 ENOG4105F9F transposase EQH48_06545 ENOG4105C2X Arabinose 5-phosphate isomerase EQH48_06550 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase EQH48_06560 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA EQH48_06565 ENOG4108IUZ ABC transporter EQH48_06570 ENOG4105DFG type I secretion outer membrane protein EQH48_06610 ENOG4108Z4U Ferredoxin EQH48_06630 ENOG4107AQZ Membrane EQH48_06635 ENOG4105BZU Histidine kinase EQH48_06640 ENOG4105D1S lipid A biosynthesis EQH48_06655 ENOG4105D2S major facilitator superfamily EQH48_06675 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) EQH48_06715 ENOG4105CNA YD repeat protein EQH48_06730 ENOG4108WAV Transcriptional regulator EQH48_06735 ENOG4105C5A transporter EQH48_06755 ENOG4108JIK carboxylase EQH48_06760 ENOG4107R4J Chloride channel EQH48_06785 ENOG4105R8C Transcriptional regulator EQH48_06795 ENOG4105E2A Dehydrogenase EQH48_06820 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EQH48_06825 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF EQH48_06845 ENOG4105MRR Transcriptional regulator (By similarity) EQH48_06855 ENOG4108HW3 (ABC) transporter EQH48_06930 ENOG4105UYK outer membrane protein a EQH48_06940 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EQH48_06970 ENOG4105EMY transcriptional regulator EQH48_06980 ENOG4107Y2X deaminase EQH48_06985 ENOG4105DJ2 Major Facilitator Superfamily EQH48_07000 ENOG4105WPN DNA integration recombination invertion protein EQH48_07010 ENOG4108Z4X TRANSCRIPTIONal EQH48_07025 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EQH48_07045 ENOG4105MWK D-amino acid dehydrogenase, small subunit EQH48_07070 ENOG4105CZJ Aldehyde dehydrogenase EQH48_07075 ENOG4107QTZ amino acid EQH48_07080 ENOG4105EJQ L-serine dehydratase EQH48_07085 ENOG4105DXM phenylacetic acid degradation protein EQH48_07090 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit EQH48_07095 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit EQH48_07100 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit EQH48_07105 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit EQH48_07110 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EQH48_07115 ENOG4105E39 Enoyl-CoA hydratase EQH48_07120 ENOG4108UKI Enoyl-CoA hydratase EQH48_07125 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EQH48_07130 ENOG4105CHU acetyl-coa acetyltransferase EQH48_07135 ENOG4105DZS Phenylacetate-CoA ligase EQH48_07140 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein EQH48_07150 ENOG4107YAU phenylacetic acid degradation protein EQH48_07210 ENOG4107VGR Catalase EQH48_07215 ENOG4105CPW cytochrome b561 EQH48_07235 ENOG4108MXF Alpha Beta Hydrolase EQH48_07240 ENOG4105MXW flavin reductase domain protein, FMN-binding EQH48_07245 ENOG4108M8W Monooxygenase EQH48_07250 ENOG4105C26 Dehydrogenase EQH48_07260 ENOG4105ETS cytosine purines uracil thiamine allantoin EQH48_07270 ENOG4105C26 Dehydrogenase EQH48_07275 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EQH48_07280 ENOG4105HEI LysR family (Transcriptional regulator EQH48_07290 ENOG4107HP6 Transcriptional regulator EQH48_07295 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase EQH48_07305 ENOG4105C4Y ABC transporter EQH48_07310 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EQH48_07315 ENOG4107RCV ABC transporter, permease EQH48_07325 ENOG4107STF Involved in phosphonate degradation (By similarity) EQH48_07330 ENOG4108KAZ Involved in phosphonate degradation (By similarity) EQH48_07335 ENOG4107RGD Major Facilitator superfamily EQH48_07340 ENOG4105C1G acyl-Coa dehydrogenase EQH48_07355 ENOG4108UKI Enoyl-CoA hydratase EQH48_07360 ENOG4105EA8 2-Nitropropane dioxygenase EQH48_07365 ENOG4105EQ0 Major Facilitator superfamily EQH48_07375 ENOG4105CHU acetyl-coa acetyltransferase EQH48_07380 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EQH48_07385 ENOG4105CHR reductase EQH48_07390 ENOG4105E39 Enoyl-CoA hydratase EQH48_07395 ENOG4105C1G acyl-Coa dehydrogenase EQH48_07400 ENOG4107RGD Major Facilitator superfamily EQH48_07405 ENOG4107QP7 CoA-transferase subunit A EQH48_07410 ENOG4107QNJ CoA-transferase subunit B EQH48_07420 ENOG4105EQ0 Major Facilitator superfamily EQH48_07430 ENOG4105CSU acyl-Coa dehydrogenase EQH48_07445 ENOG4105CC0 LysR family Transcriptional regulator EQH48_07460 ENOG4105E39 Enoyl-CoA hydratase EQH48_07465 ENOG4107QX3 carboxylase EQH48_07470 ENOG4105C1G acyl-Coa dehydrogenase EQH48_07475 ENOG4105R8C Transcriptional regulator EQH48_07480 ENOG4105CEY Amp-dependent synthetase and ligase EQH48_07500 ENOG4105HEI LysR family (Transcriptional regulator EQH48_07545 ENOG4105CYX Short-chain dehydrogenase reductase Sdr EQH48_07565 ENOG4105KT5 UmuD protein EQH48_07575 ENOG4105EW9 transcriptional regulator AsnC family EQH48_07585 ENOG4105BZU Histidine kinase EQH48_07590 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EQH48_07605 ENOG4105EAD ABC transporter EQH48_07610 ENOG4108HW4 amino acid AbC transporter EQH48_07615 ENOG4105CDA abc transporter atp-binding protein EQH48_07620 ENOG4107RP9 extracellular solute-binding protein, family 3 EQH48_07625 ENOG4105CT1 (ABC) transporter EQH48_07635 ENOG4105EXG Transcriptional regulator EQH48_07650 ENOG4105C9B Cysteine desulfurase EQH48_07655 ENOG4105ESN nucleotide-binding protein EQH48_07660 ENOG4105D7W serine acetyltransferase EQH48_07670 ENOG4105CHR reductase EQH48_07675 ENOG4105CBN LysR family transcriptional regulator EQH48_07680 ENOG4105CYM Glutathione S-transferase EQH48_07685 ENOG4108SHQ Glutathione S-transferase EQH48_07690 ENOG4105CMU LysR family (Transcriptional regulator EQH48_07695 ENOG4105VAW lrga family EQH48_07700 ENOG41067MG lrgb family EQH48_07720 ENOG4105DXI Major Facilitator superfamily EQH48_07730 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase EQH48_07735 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) EQH48_07750 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase EQH48_07755 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EQH48_07770 ENOG4108K70 Transcriptional regulator EQH48_07775 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EQH48_07785 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EQH48_07790 ENOG4105C4M (Ubiquinol oxidase) subunit I EQH48_07815 ENOG4105C54 Major Facilitator superfamily EQH48_07835 ENOG4106FTQ Taurine ABC transporter, periplasmic EQH48_07840 ENOG4108IY8 ABC, transporter EQH48_07845 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EQH48_07850 ENOG4105E2B Taurine dioxygenase EQH48_07860 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EQH48_07870 ENOG4105CBN LysR family transcriptional regulator EQH48_07880 ENOG4105CPN adenine deaminase EQH48_07895 ENOG41082YX Transcriptional regulator, arsr family EQH48_07900 ENOG4105D6J arsenicaL-resistance protein EQH48_07905 ENOG4108KB2 LysR family Transcriptional regulator EQH48_07920 ENOG4108JU3 Alkyl hydroperoxide reductase EQH48_07945 ENOG4105C0B DNA polymerase III (alpha subunit) EQH48_07960 ENOG4105CHM Aminotransferase EQH48_07970 ENOG4108V06 Glutathione peroxidase EQH48_07975 ENOG4105E7U AraC family transcriptional regulator EQH48_08005 ENOG4105ZED uncharacterized protein ygaH EQH48_08010 ENOG4108UMN azlc family EQH48_08035 ENOG4105C3G gtp-binding protein EQH48_08040 ENOG4108UMI ABC transporter, permease EQH48_08045 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EQH48_08050 ENOG4105D01 (LipO)protein EQH48_08055 ENOG4105D01 (LipO)protein EQH48_08070 ENOG4107T8P acyl-Coa dehydrogenase EQH48_08085 ENOG4105EAD ABC transporter EQH48_08090 ENOG4105DRP amino acid AbC transporter EQH48_08095 ENOG4105CDA abc transporter atp-binding protein EQH48_08105 ENOG4105EW9 transcriptional regulator AsnC family EQH48_08120 ENOG41067SE Tetr family transcriptional regulator EQH48_08150 ENOG4105CC0 LysR family Transcriptional regulator EQH48_08160 ENOG4105ETS cytosine purines uracil thiamine allantoin EQH48_08170 ENOG4108IPJ Membrane EQH48_08205 ENOG4105GQR Chaperone EQH48_08210 ENOG4105X0I Fimbrial EQH48_08230 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EQH48_08235 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) EQH48_08255 ENOG4108HWY Beta-lactamase EQH48_08285 ENOG4105CV1 Transketolase (EC 2.2.1.1) EQH48_08295 ENOG4108YYC ycei family EQH48_08305 ENOG4108T58 Mg2 transport protein CorA EQH48_08320 ENOG4105YGK Pfam:UPF0157 EQH48_08325 ENOG4105C26 Dehydrogenase EQH48_08330 ENOG4105EW9 transcriptional regulator AsnC family EQH48_08335 ENOG4105CK7 Sodium proline symporter EQH48_08340 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EQH48_08350 ENOG4108ZX5 transcriptional regulator EQH48_08360 ENOG4105BZ1 (ABC) transporter EQH48_08365 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme EQH48_08370 ENOG4105XPP Protein of unknown function (DUF1275) EQH48_08380 ENOG41080HT Transcriptional regulator, arsr family EQH48_08390 ENOG4105EZE Cupin 4 family protein EQH48_08395 ENOG4108UHJ MAF-like protein EQH48_08415 ENOG4105D2N Aldolase EQH48_08420 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EQH48_08425 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) EQH48_08430 ENOG4105EHM Aminoglycoside phosphotransferase EQH48_08435 ENOG4108S0S Nucleotidyl transferase EQH48_08445 ENOG4107QJE Chromosome Partitioning Protein EQH48_08450 ENOG4105FA0 parb-like partition protein EQH48_08465 ENOG4105BZ1 (ABC) transporter EQH48_08470 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) EQH48_08480 ENOG4107QRG dna polymerase iii EQH48_08490 ENOG4105F8V Hydrolase, tatD family EQH48_08515 ENOG4108RTD type II secretion system protein K EQH48_08535 ENOG4108Z6B deaminase EQH48_08550 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) EQH48_08555 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) EQH48_08575 ENOG4107RN6 Monooxygenase EQH48_08585 ENOG4105D6Z AFG1 family ATPase EQH48_08590 ENOG4107QP3 malate synthase g EQH48_08600 ENOG4105SG9 biopolymer transport protein, ExbD EQH48_08640 ENOG4105DGW oligopeptidase A EQH48_08650 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EQH48_08670 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase EQH48_08685 ENOG4105K4T epimerase EQH48_08690 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) EQH48_08710 ENOG4108JA2 transcriptioN-repair coupling factor EQH48_08720 ENOG4105F8J Adenylate Guanylate cyclase EQH48_08725 ENOG4108ZIT Ferredoxin, 2FE-2S EQH48_08740 ENOG4108Z4V iron-sulfur cluster assembly EQH48_08745 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins EQH48_08755 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family EQH48_08770 ENOG4105K70 DNA-binding protein EQH48_08775 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EQH48_08780 ENOG4105E7U AraC family transcriptional regulator EQH48_08785 ENOG4105EEF Alkane 1-monooxygenase EQH48_08790 ENOG4105C1G acyl-Coa dehydrogenase EQH48_08795 ENOG4105C1G acyl-Coa dehydrogenase EQH48_08810 ENOG4108Z66 YbaK ebsC protein EQH48_08830 ENOG4105DUU IucA IucC family protein EQH48_08835 ENOG4105DJU Siderophore biosynthesis protein EQH48_08890 ENOG4108YZT Adenosylcobinamide kinase EQH48_08895 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) EQH48_08915 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EQH48_08920 ENOG4107TSN permease EQH48_08940 ENOG4105CNM Receptor EQH48_08945 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EQH48_08980 ENOG4105CJ1 ABC, transporter EQH48_08985 ENOG4107QWP ABC-2 type transporter EQH48_08990 ENOG4107QWP ABC-2 type transporter EQH48_09015 ENOG4105K59 histidine triad (HIT) protein EQH48_09045 ENOG4105F2W methyltransferase EQH48_09055 ENOG4105C28 cystathionine EQH48_09070 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) EQH48_09115 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EQH48_09120 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) EQH48_09145 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EQH48_09150 ENOG4107R0V Pyruvate dehydrogenase EQH48_09155 ENOG4105CPP Dehydrogenase, E1 component EQH48_09170 ENOG4105CHR reductase EQH48_09180 ENOG4105FFC UPF0187 protein EQH48_09190 ENOG4107QPB Beta-lactamase domain protein EQH48_09200 ENOG4108VCT Sulfite exporter TauE/SafE EQH48_09215 ENOG4105UEI Transcriptional Regulator AraC Family EQH48_09220 ENOG4105KVH Transcriptional regulator EQH48_09225 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) EQH48_09235 ENOG4105FDP GntR family transcriptional regulator EQH48_09250 ENOG4106FTQ Taurine ABC transporter, periplasmic EQH48_09255 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EQH48_09275 ENOG4105CSH Transporter EQH48_09285 ENOG4108IJ0 Aspartate ammonia-lyase EQH48_09300 ENOG4107YNJ LysR family Transcriptional regulator EQH48_09310 ENOG4105CHU acetyl-coa acetyltransferase EQH48_09315 ENOG4105CRW Short chain fatty acid transporter EQH48_09320 ENOG4107QNJ CoA-transferase subunit B EQH48_09330 ENOG4108M0I Transcriptional regulator EQH48_09340 ENOG4105CY2 Citrate transporter EQH48_09345 ENOG4105DTD Dehydrogenase EQH48_09350 ENOG4105CF7 AraC family transcriptional regulator EQH48_09355 ENOG4105D2S major facilitator superfamily EQH48_09365 ENOG4105CHR reductase EQH48_09390 ENOG4105F57 Anthranilate dioxygenase reductase EQH48_09395 ENOG4108YS2 small subunit EQH48_09400 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit EQH48_09405 ENOG4105F4R Transcriptional regulator mode EQH48_09410 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EQH48_09415 ENOG4105E0C molybdate abc transporter EQH48_09420 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) EQH48_09425 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase EQH48_09430 ENOG4105WQI isochorismatase EQH48_09440 ENOG4107T31 5'-nucleotidase EQH48_09475 ENOG4108IGT Dipeptidase EQH48_09500 ENOG4107RZC phospholipase d EQH48_09550 ENOG4105X0I Fimbrial EQH48_09570 ENOG4105CJP fad dependent oxidoreductase EQH48_09590 ENOG4105CT3 Monooxygenase EQH48_09600 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EQH48_09605 ENOG4105BZS acriflavin resistance protein EQH48_09610 ENOG4105C1P efflux transporter, rnd family, mfp subunit EQH48_09615 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EQH48_09620 ENOG4105E0F Histidine kinase EQH48_09625 ENOG4108821 RND type efflux pump EQH48_09630 ENOG4108R6W Transcriptional regulator, ARAC family EQH48_09645 ENOG4108BAS reductase EQH48_09700 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) EQH48_09740 ENOG4108UAJ Transcriptional regulator EQH48_09820 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EQH48_09840 ENOG4105E0A ABC, transporter EQH48_09845 ENOG4105EHG Permease protein EQH48_09855 ENOG4105DQ4 alcohol dehydrogenase EQH48_09870 ENOG4105CF7 AraC family transcriptional regulator EQH48_09875 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EQH48_09885 ENOG4105EXW epimerase dehydratase EQH48_09890 ENOG4105DDW LysR family Transcriptional regulator EQH48_09900 ENOG4105C01 Dihydroxy-acid dehydratase EQH48_09905 ENOG4105CZJ Aldehyde dehydrogenase EQH48_09920 ENOG4105CW7 secretion protein, HlyD family EQH48_09940 ENOG4105JSC dimethylmenaquinone methyltransferase EQH48_09945 ENOG4108JQ1 Dehydrogenase EQH48_09970 ENOG4106KR7 LysR family Transcriptional regulator EQH48_09985 ENOG4105FDP GntR family transcriptional regulator EQH48_10015 ENOG4105CKT filamentous hemagglutinin EQH48_10020 ENOG4105D5K Hemolysin activator protein EQH48_10035 ENOG4105CH2 amidohydrolase EQH48_10045 ENOG4105CKD glutathione-regulated potassium-efflux system protein EQH48_10050 ENOG4105D8V Glucose sorbosone dehydrogenase EQH48_10055 ENOG4105EJC lysr family transcriptional regulator EQH48_10060 ENOG4105CHJ isochorismatase hydrolase EQH48_10080 ENOG41062QD Membrane EQH48_10090 ENOG4108JU7 Transcriptional regulator EQH48_10095 ENOG4105CHR reductase EQH48_10100 ENOG4105C1G acyl-Coa dehydrogenase EQH48_10120 ENOG4105CZJ Aldehyde dehydrogenase EQH48_10140 ENOG4107EJG GntR family transcriptional regulator EQH48_10150 ENOG4108KB2 LysR family Transcriptional regulator EQH48_10155 ENOG4105DTQ mandelate racemase muconate lactonizing EQH48_10160 ENOG4105NN7 muconolactone delta-isomerase EQH48_10170 ENOG4107QP7 CoA-transferase subunit A EQH48_10175 ENOG4107QNJ CoA-transferase subunit B EQH48_10180 ENOG4105CHU acetyl-coa acetyltransferase EQH48_10185 ENOG4105F2Z 3-oxoadipate enol-lactonase EQH48_10195 ENOG4105C26 Dehydrogenase EQH48_10205 ENOG4105F11 amine oxidase EQH48_10225 ENOG4105CHR reductase EQH48_10235 ENOG4105FUY alpha subunit EQH48_10255 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EQH48_10265 ENOG4105DNH Major Facilitator EQH48_10290 ENOG4105C1G acyl-Coa dehydrogenase EQH48_10295 ENOG4108PTX LysR family Transcriptional regulator EQH48_10300 ENOG4107HP6 Transcriptional regulator EQH48_10315 ENOG4105MD1 YeeE YedE family protein EQH48_10325 ENOG4105DZG Dehydrogenase EQH48_10330 ENOG4105TW1 Carbohydrate-selective porin OprB EQH48_10335 ENOG4106JPM 3-dehydroshikimate dehydratase EQH48_10340 ENOG4105FF2 Type I DHQase EQH48_10345 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha EQH48_10350 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta EQH48_10355 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EQH48_10360 ENOG4105D2S major facilitator superfamily EQH48_10365 ENOG4105F2Z 3-oxoadipate enol-lactonase EQH48_10370 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase EQH48_10375 ENOG4105CHU acetyl-coa acetyltransferase EQH48_10380 ENOG4107QNJ CoA-transferase subunit B EQH48_10385 ENOG4107QP7 CoA-transferase subunit A EQH48_10395 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) EQH48_10400 ENOG4107VMU Membrane EQH48_10445 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EQH48_10460 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EQH48_10470 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EQH48_10475 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) EQH48_10505 ENOG4105C7B Threonine dehydratase EQH48_10515 ENOG4105CZN Potassium uptake protein EQH48_10520 ENOG4105HDD phospholipase EQH48_10530 ENOG4105E0K tonB-dependent siderophore receptor EQH48_10545 ENOG4105PV3 Inner membrane protein yqiJ EQH48_10550 ENOG4105F9F transposase EQH48_10560 ENOG4105F9F transposase EQH48_10570 ENOG4105C4M (Ubiquinol oxidase) subunit I EQH48_10575 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EQH48_10595 ENOG41068P6 UPF0319 protein EQH48_10605 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EQH48_10630 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EQH48_10635 ENOG4105C8Y Acetylornithine aminotransferase EQH48_10640 ENOG4105M2J Glutaredoxin EQH48_10650 ENOG4105CC0 LysR family Transcriptional regulator EQH48_10655 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EQH48_10660 ENOG4105CWM branched-chain amino acid transport system II carrier protein EQH48_10685 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EQH48_10690 ENOG4105DE4 1-phosphofructokinase EQH48_10695 ENOG4105DM4 PTS System EQH48_10715 ENOG4105BZU Histidine kinase EQH48_10725 ENOG4105D8V Glucose sorbosone dehydrogenase EQH48_10730 ENOG4108RAV Conserved protein EQH48_10735 ENOG4105CHH sulfate transporter EQH48_10750 ENOG4105C85 amino acid EQH48_10760 ENOG4105F7P transcriptional regulator AsnC family EQH48_10785 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 EQH48_10790 ENOG4105VEJ Heat shock protein EQH48_10800 ENOG4105Y3E Modulates RecA activity (By similarity) EQH48_10815 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EQH48_10840 ENOG4105DZP Membrane-associated zinc metalloprotease EQH48_10850 ENOG4105KNE Phosphatidate cytidylyltransferase EQH48_10855 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) EQH48_10880 ENOG4105CUX Signal transduction histidine kinase EQH48_10885 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EQH48_10945 ENOG4105CMR udp-glucose 4-epimerase EQH48_10950 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) EQH48_10970 ENOG4105T38 integral membrane protein EQH48_10975 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EQH48_10985 ENOG4105CVM Molybdenum cofactor synthesis domain protein EQH48_10990 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EQH48_11005 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EQH48_11025 ENOG4108IFG nitrite reductase, (NAD(P)H) EQH48_11030 ENOG4107QZF nitrite reductase NADPH large subunit EQH48_11040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EQH48_11065 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein EQH48_11070 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EQH48_11090 ENOG4105DIJ Phosphoethanolamine transferase EQH48_11370 ENOG4105CBC glutamate synthase EQH48_11400 ENOG4105C0A alcohol dehydrogenase EQH48_11410 ENOG4105HSS phospholipase C EQH48_11415 ENOG4107QMP dna polymerase iii subunits gamma and tau EQH48_11440 ENOG4105CHR reductase EQH48_11445 ENOG4105CHU acetyl-coa acetyltransferase EQH48_11455 ENOG4105C5Q Transcriptional regulator EQH48_11460 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EQH48_11465 ENOG4108NIW Leucine export protein LeuE EQH48_11470 ENOG4105EW9 transcriptional regulator AsnC family EQH48_11475 ENOG4105DKK Benzoate EQH48_11485 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EQH48_11500 ENOG41081QV Universal stress protein EQH48_11505 ENOG4105C5H ABC transporter EQH48_11525 ENOG4105CNM Receptor EQH48_11560 ENOG4105CUY Mechanosensitive ion channel EQH48_11570 ENOG4105R8C Transcriptional regulator EQH48_11585 ENOG4105EW9 transcriptional regulator AsnC family EQH48_11590 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) EQH48_11600 ENOG4105EMU Dehydrogenase EQH48_11610 ENOG4105CD8 aminopeptidase N EQH48_11630 ENOG4105F4I Transcriptional regulator EQH48_11640 ENOG4107QUV Domain protein EQH48_11645 ENOG4105C0A alcohol dehydrogenase EQH48_11655 ENOG4107RR1 TRANSCRIPTIONal EQH48_11665 ENOG4107R55 ethanolamine transporter EQH48_11670 ENOG4105CPD ethanolamine ammonia-lyase EQH48_11675 ENOG4107FQ9 ethanolamine ammonia-lyase EQH48_11680 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EQH48_11705 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) EQH48_11715 ENOG4108RCM Nitroreductase EQH48_11720 ENOG4108TZV Membrane EQH48_11725 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EQH48_11735 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) EQH48_11740 ENOG4105K8N protein family UPF0079, ATPase EQH48_11775 ENOG4105DZ2 Transcriptional regulator EQH48_11790 ENOG4105F27 Major Facilitator EQH48_11795 ENOG4105EYW Ion transport protein EQH48_11805 ENOG4107QIJ Aconitate hydratase 2 EQH48_11825 ENOG4105CFU surface antigen EQH48_11830 ENOG4107S74 Lysophospholipid transporter LplT EQH48_11845 ENOG4105CFQ glutamine synthetase EQH48_11850 ENOG4105EEX Two component transcriptional regulator (Winged helix family EQH48_11855 ENOG4105C08 Histidine kinase EQH48_11865 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EQH48_11870 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EQH48_11890 ENOG4105D06 uba thif-type nad fad binding protein EQH48_11895 ENOG4108MEJ flavin reductase domain protein EQH48_11905 ENOG4105C1G acyl-Coa dehydrogenase EQH48_11920 ENOG4105GVF (ABC) transporter EQH48_11925 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EQH48_11930 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EQH48_11945 ENOG4105CC0 LysR family Transcriptional regulator EQH48_11965 ENOG4105DEN Luciferase family EQH48_11975 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD EQH48_11980 ENOG4105CND Glycosyl transferase, family 2 EQH48_11985 ENOG4107BJW polysaccharide deacetylase EQH48_12010 ENOG4105E2S oxidase) subunit II EQH48_12015 ENOG4105BZ9 Cytochrome C oxidase, subunit I EQH48_12020 ENOG4105CCU oxidase (Subunit III) EQH48_12025 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) EQH48_12050 ENOG4105CDU Replicative dna helicase EQH48_12055 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EQH48_12105 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) EQH48_12110 ENOG4105DC1 bifunctional purine biosynthesis protein purh EQH48_12115 ENOG4105C12 Phosphoribosylglycinamide synthetase EQH48_12125 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EQH48_12130 ENOG4108UMI ABC transporter, permease EQH48_12135 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EQH48_12145 ENOG4105CK2 sodium dicarboxylate symporter EQH48_12185 ENOG4105DY2 Paraquat-inducible protein b EQH48_12190 ENOG4105F1S paraquat-inducible protein a EQH48_12205 ENOG4105CEB Aspartate aminotransferase EQH48_12230 ENOG4105CSH Transporter EQH48_12295 ENOG4105JXH GntR family transcriptional regulator EQH48_12305 ENOG4105D6U Sodium Glutamate Symporter EQH48_12335 ENOG4105H4F exported protein EQH48_12370 ENOG4105C26 Dehydrogenase EQH48_12375 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EQH48_12380 ENOG4105EVZ LysR family transcriptional regulator EQH48_12405 ENOG4105D9P serine threonine protein kinase EQH48_12430 ENOG4105VCC 30S ribosomal protein S21 EQH48_12435 ENOG4105KTH gatB Yqey EQH48_12440 ENOG4105ERG peptidase m48, ste24p EQH48_12445 ENOG4105C5I Dehydrogenase EQH48_12460 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase EQH48_12495 ENOG41069NU Nitroreductase EQH48_12505 ENOG4105C1J atp-dependent rna helicase EQH48_12510 ENOG4105VEQ Cold shock protein EQH48_12520 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EQH48_12525 ENOG4105M08 Membrane EQH48_12555 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) EQH48_12560 ENOG4105CIN aminoacyl-histidine dipeptidase EQH48_12570 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase EQH48_12575 ENOG4105CQC Prephenate dehydratase EQH48_12580 ENOG4105NIV Esterase EQH48_12585 ENOG4105C1G acyl-Coa dehydrogenase EQH48_12590 ENOG4105CK2 sodium dicarboxylate symporter EQH48_12600 ENOG4107QYG anthranilate phosphoribosyltransferase EQH48_12605 ENOG4105VUT cytoplasmic protein EQH48_12610 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) EQH48_12615 ENOG4105BZ4 penicillin-binding protein EQH48_12625 ENOG4105M6F mutator MutT protein EQH48_12635 ENOG4105DHQ Histidine kinase EQH48_12640 ENOG4105XJC Two component transcriptional regulator (Winged helix family EQH48_12650 ENOG4107QHF type ii secretion system protein e EQH48_12660 ENOG4108R96 Methyltransferase, YaeB family EQH48_12665 ENOG4105DP0 ferredoxin-NADP reductase EQH48_12670 ENOG4105JAB phenazine biosynthesis protein, phzf family EQH48_12675 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EQH48_12680 ENOG4105CFP Peptidase U32 EQH48_12685 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EQH48_12695 ENOG4108JEH abc transporter atp-binding protein EQH48_12700 ENOG4106YG3 ABC transporter EQH48_12705 ENOG4105DSP amino acid AbC transporter EQH48_12710 ENOG4105E89 ABC transporter EQH48_12720 ENOG4105ENT Efflux transporter rnd family, mfp subunit EQH48_12730 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EQH48_12765 ENOG4105DA5 (ABC) transporter EQH48_12770 ENOG4105E3A (ABC) transporter EQH48_12785 ENOG4105CNI cell division protein FtsW EQH48_12790 ENOG4105CVE Lytic murein transglycosylase EQH48_12830 ENOG4105CE9 30S ribosomal protein S2 EQH48_12835 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EQH48_12845 ENOG4107RNU major facilitator superfamily MFS_1 EQH48_12855 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) EQH48_12860 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EQH48_12865 ENOG4107QPN acyl-Coa dehydrogenase EQH48_12880 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) EQH48_12885 ENOG4105SYT Methylenetetrahydrofolate reductase EQH48_12890 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EQH48_12895 ENOG4105BZU Histidine kinase EQH48_12900 ENOG4105C6K Malic enzyme EQH48_12910 ENOG4105C0H protease EQH48_12915 ENOG4107QNR UPF0135 protein EQH48_12920 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EQH48_12955 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) EQH48_12965 ENOG4105C5F glutamine synthetase EQH48_12970 ENOG4105DUX Transporter EQH48_12980 ENOG4105DFP Integrase EQH48_13080 ENOG4105UPP uncharacterized protein ydcA EQH48_13375 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EQH48_13400 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EQH48_13410 ENOG4105D82 Glutamate dehydrogenase EQH48_13415 ENOG4108R3D Electron transport complex EQH48_13420 ENOG4105CSM endonuclease III EQH48_13445 ENOG4105CJN penicillin-binding protein EQH48_13450 ENOG4106H78 methyltransferase EQH48_13465 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) EQH48_13475 ENOG4105CQM Urea amidohydrolase subunit alpha EQH48_13505 ENOG4107RET Isocitrate lyase EQH48_13515 ENOG4105C37 (CBS) domain EQH48_13525 ENOG4105D4T Citrate transporter EQH48_13540 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) EQH48_13555 ENOG4108MRJ EQH48_13575 ENOG4105VCQ rubredoxin EQH48_13580 ENOG4107QZF nitrite reductase NADPH large subunit EQH48_13590 ENOG4105C5Q Transcriptional regulator EQH48_13620 ENOG4107U91 Rhomboid family EQH48_13625 ENOG4105CV6 ABC transporter, permease EQH48_13630 ENOG4108I0Y (ABC) transporter EQH48_13635 ENOG4108UJV acyl-CoA thioesterase i EQH48_13655 ENOG4107RNH Outer membrane receptor FepA EQH48_13670 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) EQH48_13675 ENOG4105E6M Sulphatase-modifying factor protein EQH48_13695 ENOG4105CJ3 phosphate transporter EQH48_13700 ENOG4105C3R Methionine synthase EQH48_13715 ENOG4105CSP Major Facilitator Superfamily EQH48_13725 ENOG4108PZW LysR family Transcriptional regulator EQH48_13740 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) EQH48_13745 ENOG4105EU0 Major facilitator Superfamily EQH48_13750 ENOG4108R6W Transcriptional regulator, ARAC family EQH48_13755 ENOG4105CSV Glutaminase EQH48_13760 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EQH48_13765 ENOG4105CSH Transporter EQH48_13775 ENOG4105C7K acetolactate synthase EQH48_13790 ENOG4105CHR reductase EQH48_13795 ENOG4108MXF Alpha Beta Hydrolase EQH48_13805 ENOG4105DJB Major Facilitator Superfamily EQH48_13810 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase EQH48_13820 ENOG4105CHR reductase EQH48_13840 ENOG41069M3 Transcriptional regulator EQH48_13855 ENOG4106YT9 Enoyl-CoA hydratase EQH48_13865 ENOG4105CND Glycosyl transferase, family 2 EQH48_13870 ENOG4107BJW polysaccharide deacetylase EQH48_13880 ENOG4108VWS Yaeq family EQH48_13890 ENOG4105CKI cobalamin synthesis protein EQH48_13910 ENOG4105C94 Transporter EQH48_13915 ENOG4105C94 Transporter EQH48_13920 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) EQH48_13945 ENOG4107QK5 Homocysteine s-methyltransferase EQH48_13950 ENOG4105D5Q Arginine ornithine antiporter EQH48_13975 ENOG4108YNN Heme oxygenase EQH48_14010 ENOG4108SF5 RNA Polymerase EQH48_14020 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EQH48_14025 ENOG4105C54 Major Facilitator superfamily EQH48_14075 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) EQH48_14080 ENOG4105C0R drug resistance transporter emrb qaca subfamily EQH48_14085 ENOG4105CW7 secretion protein, HlyD family EQH48_14090 ENOG4108VUY thioesterase Superfamily protein EQH48_14095 ENOG4105D52 delta-aminolevulinic acid dehydratase EQH48_14100 ENOG4105MWK D-amino acid dehydrogenase, small subunit EQH48_14105 ENOG4105ECP epimerase EQH48_14125 ENOG4107RH8 nuclease SbcCD subunit D EQH48_14130 ENOG4105EYH Exonuclease EQH48_14135 ENOG4105DFA alanine racemase domain protein EQH48_14140 ENOG4105CZX twitching motility protein EQH48_14145 ENOG4105CZX twitching motility protein EQH48_14150 ENOG41090R7 Ferric uptake EQH48_14180 ENOG4105E7A Glutamine amidotransferase EQH48_14195 ENOG4107QKV phosphomannomutase EQH48_14205 ENOG4105C4R Atp-dependent dna helicase EQH48_14210 ENOG4108ZG0 Ompa motb domain protein EQH48_14215 ENOG4106HNH Acyl-transferase EQH48_14230 ENOG4107QMS site-determining protein EQH48_14255 ENOG4105CNU cell division protein FtsK EQH48_14260 ENOG4105C3M thioredoxin reductase EQH48_14265 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) EQH48_14275 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EQH48_14320 ENOG4108YXA Membrane EQH48_14325 ENOG4105EUB pirin domain protein EQH48_14335 ENOG4105C4K Nad synthetase EQH48_14350 ENOG4105E3J oxidoreductase EQH48_14355 ENOG4105C26 Dehydrogenase EQH48_14360 ENOG4105DVW rieske (2Fe-2S) EQH48_14370 ENOG4105C94 Transporter EQH48_14375 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EQH48_14380 ENOG4105EJC lysr family transcriptional regulator EQH48_14400 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EQH48_14420 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EQH48_14425 ENOG4105C34 Pseudouridine synthase EQH48_14430 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane EQH48_14435 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EQH48_14450 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) EQH48_14480 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EQH48_14510 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EQH48_14520 ENOG4105DWF phosphomethylpyrimidine kinase EQH48_14525 ENOG4109066 lysm domain bon superfamily protein EQH48_14535 ENOG4105CHR reductase EQH48_14540 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EQH48_14550 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein EQH48_14555 ENOG4108BPE -transporting atpase EQH48_14560 ENOG4107RTD sua5 ycio yrdc ywlc family protein EQH48_14565 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) EQH48_14570 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) EQH48_14575 ENOG4105FE9 pseudouridine synthase EQH48_14585 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EQH48_14590 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) EQH48_14600 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EQH48_14605 ENOG4108K4C ec 3.1.3.12 EQH48_14610 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase EQH48_14615 ENOG4106UW1 Major Facilitator superfamily EQH48_14635 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) EQH48_14645 ENOG4105HF0 Membrane EQH48_14660 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY EQH48_14670 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) EQH48_14730 ENOG4105D1F ATP-binding protein EQH48_14740 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) EQH48_14770 ENOG4105K6H D-cysteine desulfhydrase EQH48_14775 ENOG4105CBX hi0933 family EQH48_14800 ENOG4105DP0 ferredoxin-NADP reductase EQH48_14805 ENOG4105DUM transcriptional regulator, lysR family EQH48_14825 ENOG4105C8S subunit m EQH48_14830 ENOG4105D65 subunit l EQH48_14840 ENOG4107UFS subunit j EQH48_14855 ENOG4108IEH NADH dehydrogenase subunit g EQH48_14860 ENOG4107QIZ NADH dehydrogenase EQH48_14865 ENOG4105GKE subunit e EQH48_14895 ENOG4105E0F Histidine kinase EQH48_14900 ENOG4107EXC regulatoR EQH48_14910 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EQH48_14920 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EQH48_14930 ENOG4105EB3 Histidine kinase EQH48_15010 ENOG4105DZG Dehydrogenase EQH48_15030 ENOG4105JAB phenazine biosynthesis protein, phzf family EQH48_15060 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) EQH48_15065 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) EQH48_15075 ENOG4105ETT transcriptional Regulator, LysR family EQH48_15095 ENOG4105CH2 amidohydrolase EQH48_15105 ENOG4106P55 Transcriptional regulator EQH48_15125 ENOG4106P55 Transcriptional regulator EQH48_15140 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EQH48_15145 ENOG4107RGD Major Facilitator superfamily EQH48_15150 ENOG4105C1G acyl-Coa dehydrogenase EQH48_15155 ENOG4105ETT transcriptional Regulator, LysR family EQH48_15190 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) EQH48_15195 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) EQH48_15200 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EQH48_15215 ENOG4105VR0 copper resistance EQH48_15220 ENOG4105E3B Multicopper oxidase EQH48_15230 ENOG4108HCJ Hydrolase EQH48_15235 ENOG4105DJV ribulose-phosphate 3-epimerase EQH48_15260 ENOG41072GX Peptidase M22 Glycoprotease EQH48_15265 ENOG4108Z0R Transferase EQH48_15325 ENOG4105CRQ synthase (Component I) EQH48_15335 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) EQH48_15340 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) EQH48_15345 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) EQH48_15415 ENOG4105K56 Transcriptional regulator EQH48_15420 ENOG4108ZHJ Organic hydroperoxide resistance protein EQH48_15425 ENOG4107QHF type ii secretion system protein e EQH48_15445 ENOG4105C2M dna polymerase I EQH48_15450 ENOG4108VIA integral membrane protein EQH48_15455 ENOG4105II7 pyrroline-5-carboxylate reductase EQH48_15460 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) EQH48_15470 ENOG4105C9X ppx gppa phosphatase EQH48_15480 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EQH48_15500 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) EQH48_15525 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) EQH48_15540 ENOG4105W39 Membrane EQH48_15545 ENOG4105CYM Glutathione S-transferase EQH48_15565 ENOG4105CEY Amp-dependent synthetase and ligase EQH48_15570 ENOG4105N42 UPF0307 protein EQH48_15575 ENOG41080Z8 PHOSPHOCARRIER protein EQH48_15595 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EQH48_15600 ENOG4105DJ0 Poly(A) Polymerase EQH48_15605 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein EQH48_15610 ENOG4105DXN mazG family EQH48_15620 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EQH48_15635 ENOG4105C6T cysteine synthase EQH48_15640 ENOG4105BZU Histidine kinase EQH48_15645 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase EQH48_15650 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EQH48_15655 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EQH48_15670 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EQH48_15675 ENOG4105W8H transhydrogenase (subunit alpha EQH48_15680 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EQH48_15710 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EQH48_15720 ENOG4107RSM transcriptional regulator EQH48_15730 ENOG4105CUZ uba thif-type nad fad binding protein EQH48_15740 ENOG4107QM5 aconitate hydratase EQH48_15745 ENOG4105F8V Hydrolase, tatD family EQH48_15760 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) EQH48_15785 ENOG4105BZU Histidine kinase EQH48_15795 ENOG4108ZP8 Acetolactate synthase small subunit EQH48_15800 ENOG4105C7K acetolactate synthase EQH48_15825 ENOG4105DJY efflux transporter, rnd family, mfp subunit EQH48_15830 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EQH48_15835 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EQH48_15840 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH EQH48_15850 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) EQH48_15855 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) EQH48_15865 ENOG4105VW4 glutaredoxin 3 EQH48_15885 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EQH48_15890 ENOG4105C2D reductase EQH48_15900 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EQH48_15930 ENOG4105C84 Histidine ammonia-lyase EQH48_15945 ENOG4105CEY Amp-dependent synthetase and ligase EQH48_15960 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) EQH48_15980 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EQH48_16000 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) EQH48_16020 ENOG4105WVQ Fe-S assembly protein IscX EQH48_16035 ENOG4105CN1 protease EQH48_16050 ENOG4106HB6 Alpha beta hydrolase EQH48_16060 ENOG4105C26 Dehydrogenase EQH48_16065 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EQH48_16070 ENOG4105C6Z Gluconate EQH48_16075 ENOG4108UHU Aldolase EQH48_16080 ENOG4105C01 Dihydroxy-acid dehydratase EQH48_16085 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) EQH48_16090 ENOG4108DNC Involved in acetate metabolism (By similarity) EQH48_16095 ENOG4107GFK fumarate EQH48_16115 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EQH48_16125 ENOG4108ESX Receptor EQH48_16135 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) EQH48_16145 ENOG4105DWV Homoserine O-trans-acetylase EQH48_16245 ENOG4105CIY formyltetrahydrofolate deformylase EQH48_16255 ENOG4107RGH Aldehyde dehydrogenase EQH48_16260 ENOG4105KDC 50s ribosomal protein l28 EQH48_16265 ENOG4105W0E 50S ribosomal protein L33 EQH48_16270 ENOG4105CKD glutathione-regulated potassium-efflux system protein EQH48_16290 ENOG4105VFU Rna-binding protein EQH48_16295 ENOG4105C4R Atp-dependent dna helicase EQH48_16310 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EQH48_16320 ENOG4105KVH Transcriptional regulator EQH48_16330 ENOG41069P5 Protein slyX homolog EQH48_16335 ENOG4105C5H ABC transporter EQH48_16340 ENOG4105N14 lysine exporter protein LysE YggA EQH48_16345 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase EQH48_16355 ENOG4105CK2 sodium dicarboxylate symporter EQH48_16410 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EQH48_16435 ENOG4105DUM transcriptional regulator, lysR family EQH48_16460 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase EQH48_16475 ENOG4108W5M transcriptional regulator EQH48_16490 ENOG4105D29 Helix-turn-helix type 11 domain protein EQH48_16495 ENOG4107XGZ Hydrolase EQH48_16500 ENOG4105EI2 Pseudouridine synthase EQH48_16510 ENOG4105C03 ribonuclease EQH48_16530 ENOG4105CBN LysR family transcriptional regulator EQH48_16535 ENOG4105EMU Dehydrogenase EQH48_16540 ENOG4105CSA Coproporphyrinogen iii oxidase EQH48_16550 ENOG4107QI1 Mate efflux family protein EQH48_16560 ENOG4107T8P acyl-Coa dehydrogenase EQH48_16605 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) EQH48_16610 ENOG4105C5X domain protein EQH48_16625 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EQH48_16635 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase EQH48_16640 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) EQH48_16645 ENOG4108JU5 Magnesium and cobalt efflux protein EQH48_16650 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) EQH48_16655 ENOG4108Z7R Chaperone CsaA EQH48_16665 ENOG4108VAU general secretion pathway protein G EQH48_16670 ENOG4105D7Q type ii secretion system EQH48_16675 ENOG4105C25 Primosomal protein n' EQH48_16680 ENOG4105CKD glutathione-regulated potassium-efflux system protein EQH48_16685 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) EQH48_16695 ENOG4105DVC DnaJ domain protein EQH48_16700 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) EQH48_16705 ENOG4107QUT magnesium and cobalt transport protein CorA EQH48_16725 ENOG4107QYX exodeoxyribonuclease v alpha EQH48_16730 ENOG4107QKA exodeoxyribonuclease V beta EQH48_16735 ENOG4105DSY exodeoxyribonuclease V, gamma EQH48_16745 ENOG4105CSR polyphosphate kinase 2 EQH48_16755 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) EQH48_16770 ENOG41061H0 Monooxygenase EQH48_16775 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase EQH48_16790 ENOG4105D65 subunit l EQH48_16795 ENOG4108ZE9 Monovalent cation H antiporter subunit C EQH48_16800 ENOG4107R4Z monovalent cation h antiporter subunit d EQH48_16805 ENOG4105SC1 monovalent cation H antiporter subunit E EQH48_16810 ENOG4105W4C monovalent cation H antiporter subunit F EQH48_16815 ENOG4105KJM monovalent cation h antiporter subunit g EQH48_16830 ENOG4105CHV Transcription elongation factor NusA EQH48_16855 ENOG4107EJC Preprotein translocase subunit SecG EQH48_16865 ENOG4107QHF type ii secretion system protein e EQH48_16880 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EQH48_16890 ENOG4105C2N RNA methyltransferase TrmH family group 3 EQH48_16905 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EQH48_16915 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) EQH48_16945 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EQH48_16950 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EQH48_17020 ENOG4107ZXU DSBA oxidoreductase EQH48_17035 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) EQH48_17050 ENOG4105D3Y Na H antiporter EQH48_17055 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EQH48_17110 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EQH48_17115 ENOG4105PM1 preprotein translocase subunit SecE EQH48_17155 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EQH48_17160 ENOG4105TV9 FHA Domain-Containing protein EQH48_17165 ENOG4105GVR general secretion pathway protein D EQH48_17180 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS EQH48_17205 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) EQH48_17210 ENOG4108NEV two component transcriptional regulator, LytTR family EQH48_17215 ENOG4108HRK Histidine kinase EQH48_17230 ENOG4108UTW Plays a role in the regulation of phosphate uptake EQH48_17235 ENOG4105DFG type I secretion outer membrane protein EQH48_17240 ENOG4108RNG Permease of the drug metabolite transporter EQH48_17265 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EQH48_17270 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EQH48_17275 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) EQH48_17280 ENOG4105CNI cell division protein FtsW EQH48_17295 ENOG4105CE1 Ferrous iron transport protein b EQH48_17305 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EQH48_17310 ENOG4105T95 Thiol disulfide interChange protein EQH48_17315 ENOG4105D6E homoserine dehydrogenase EQH48_17325 ENOG41061WM D-Alanyl-D-Alanine EQH48_17335 ENOG4107TUY Histidine kinase EQH48_17340 ENOG4105F9F transposase EQH48_17345 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EQH48_17350 ENOG4105CN1 protease EQH48_17355 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) EQH48_17360 ENOG4108K5H permease YjgP YjgQ family protein EQH48_17400 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EQH48_17410 ENOG4105BZU Histidine kinase EQH48_17425 ENOG4105C0P Mg chelatase subunit ChlI EQH48_17440 ENOG4108HWY Beta-lactamase EQH48_17450 ENOG4105F6A helicase EQH48_17465 ENOG4105CHH sulfate transporter EQH48_17510 ENOG4105C0P Mg chelatase subunit ChlI EQH48_17515 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EQH48_17525 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EQH48_17540 ENOG4105EPF Outer membrane porin EQH48_17545 ENOG4105F0N pyrophosphate phospho-hydrolase EQH48_17560 ENOG4105CEY Amp-dependent synthetase and ligase EQH48_17565 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EQH48_17570 ENOG41079KZ Major Facilitator Superfamily EQH48_17575 ENOG4105EN6 Membrane EQH48_17580 ENOG4105K5B UPF0225 protein EQH48_17585 ENOG4105EE5 Membrane protein terC EQH48_17590 ENOG4108URH decarboxylase EQH48_17595 ENOG4105C0R drug resistance transporter emrb qaca subfamily EQH48_17605 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EQH48_17620 ENOG4105CCT upf0313 protein EQH48_17640 ENOG4105CS1 NAD(P)H quinone oxidoreductase EQH48_17650 ENOG4105C6T cysteine synthase EQH48_17685 ENOG4105Y7M Transcriptional regulator, TetR family EQH48_17720 ENOG4105C79 DNA protecting protein DprA EQH48_17735 ENOG4108IND Tetr family transcriptional regulator EQH48_17740 ENOG4107RTG Major Facilitator superfamily EQH48_17750 ENOG4108V06 Glutathione peroxidase EQH48_17760 ENOG41090VV Protein of unknown function (DUF2846) EQH48_17795 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) EQH48_17820 ENOG4105FDK ABC transporter EQH48_17825 ENOG4105FAV ABC, transporter EQH48_17835 ENOG4105EZR dyp-type peroxidase family protein EQH48_17840 ENOG4107R1I NAD-dependent malic enzyme EQH48_17865 ENOG4105EUB pirin domain protein EQH48_17900 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EQH48_17905 ENOG4106MP8 UPF0754 membrane protein EQH48_17910 ENOG4108VBZ doxx family EQH48_17915 ENOG4105DQR SNARE associated Golgi EQH48_17930 ENOG4107QJE Chromosome Partitioning Protein EQH48_17940 ENOG4107PSF BolA-like protein EQH48_17985 ENOG4105C1G acyl-Coa dehydrogenase EQH48_18010 ENOG4105CSH Transporter EQH48_18015 ENOG4105E39 Enoyl-CoA hydratase EQH48_18020 ENOG4105E39 Enoyl-CoA hydratase EQH48_18025 ENOG4105C1G acyl-Coa dehydrogenase EQH48_18035 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EQH48_18040 ENOG4105C26 Dehydrogenase EQH48_18050 ENOG4105C85 amino acid EQH48_18055 ENOG4105C85 amino acid EQH48_18060 ENOG4105M4H endoribonuclease L-psp EQH48_18075 ENOG4105EW9 transcriptional regulator AsnC family EQH48_18100 ENOG4105D3G Pseudouridine synthase EQH48_18150 ENOG4108I0Z Aconitate hydratase EQH48_18155 ENOG4105BZN citrate synthase EQH48_18160 ENOG4105CR4 methylisocitrate lyase EQH48_18165 ENOG4105DRR Transcriptional regulator, GntR family EQH48_18175 ENOG4105CGF Aromatic amino acid aminotransferase EQH48_18180 ENOG4105CXG d-lactate dehydrogenase EQH48_18190 ENOG41073TP transcriptional regulator EQH48_18195 ENOG4105DAA L-lactate EQH48_18200 ENOG4107QKV phosphomannomutase EQH48_18210 ENOG4105CMR udp-glucose 4-epimerase EQH48_18220 ENOG4105C6Y Udp-glucose 6-dehydrogenase EQH48_18225 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EQH48_18230 ENOG4105D3Q Sugar transferase EQH48_18235 ENOG4108RYC glycosyltransferase EQH48_18240 ENOG4105CG5 Glycosyl transferase (Group 1 EQH48_18255 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) EQH48_18270 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EQH48_18275 ENOG4105J5G Transferase hexapeptide repeat containing protein EQH48_18280 ENOG4107R5Z Oxidoreductase domain protein EQH48_18285 ENOG4107QQG Dehydrogenase EQH48_18290 ENOG4105DAY polysaccharide export protein EQH48_18300 ENOG4105D75 Capsular exopolysaccharide family EQH48_18305 ENOG4108V1T peptidylprolyl cis-trans isomerase EQH48_18310 ENOG4108V1T peptidylprolyl cis-trans isomerase EQH48_18315 ENOG4105CJR Integral membrane protein (MviN EQH48_18320 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EQH48_18325 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EQH48_18335 ENOG4105HSS phospholipase C EQH48_18360 ENOG41062JF Transcriptional regulator EQH48_18375 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EQH48_18380 ENOG4105UBK short-chain dehydrogenase reductase EQH48_18395 ENOG4107QZM n-acetylglutamate synthase EQH48_18400 ENOG4105GVF (ABC) transporter EQH48_18405 ENOG4105GVF (ABC) transporter EQH48_18410 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EQH48_18415 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EQH48_18420 ENOG4108VM9 ABC, transporter EQH48_18425 ENOG4108R86 Transcriptional regulator EQH48_18430 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) EQH48_18440 ENOG4105DTN riboflavin biosynthesis protein ribF EQH48_18445 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) EQH48_18455 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase EQH48_18495 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EQH48_18550 ENOG4105CVE Lytic murein transglycosylase EQH48_18555 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EQH48_18560 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EQH48_18575 ENOG4105DFU Cell wall formation (By similarity) EQH48_18585 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EQH48_18590 ENOG4105DU1 integral membrane protein, terc EQH48_18600 ENOG4106032 Glutathionylspermidine synthase EQH48_18610 ENOG4107QUY Guanine deaminase EQH48_18615 ENOG4108UGV hypoxanthine phosphoribosyltransferase EQH48_18625 ENOG4105T95 Thiol disulfide interChange protein EQH48_18630 ENOG4105PGM cation diffusion facilitator family transporter EQH48_18645 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EQH48_18660 ENOG4105VG0 50S ribosomal protein l34 EQH48_18695 ENOG4105C4W S-formylglutathione hydrolase EQH48_18725 ENOG4105F9F transposase