locus-tag class description EP550_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EP550_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EP550_00030 ENOG4105DQR SNARE associated Golgi EP550_00035 ENOG4105C5H ABC transporter EP550_00040 ENOG4108821 RND type efflux pump EP550_00045 ENOG4108821 RND type efflux pump EP550_00050 ENOG4108821 RND type efflux pump EP550_00060 ENOG4105D74 hydrolase EP550_00065 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) EP550_00070 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) EP550_00115 ENOG4105C8J )-transporter EP550_00125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B EP550_00150 ENOG4108W5M transcriptional regulator EP550_00155 ENOG4105C2W permease EP550_00165 ENOG4108IG5 Transcriptional regulator EP550_00170 ENOG4105DJY efflux transporter, rnd family, mfp subunit EP550_00205 ENOG4105F27 Major Facilitator EP550_00210 ENOG4105CV8 reductase EP550_00215 ENOG4105HEI LysR family (Transcriptional regulator EP550_00235 ENOG4105DQ4 alcohol dehydrogenase EP550_00240 ENOG4108R3E Dna-3-methyladenine glycosylase i EP550_00255 ENOG4105CEN a g-specific adenine glycosylase EP550_00275 ENOG4108ZZ3 UPF0260 protein EP550_00285 ENOG4105D1H recombination factor protein RarA EP550_00290 ENOG4105S64 Formate nitrite transporter EP550_00315 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EP550_00320 ENOG4108RWI nicotinamidase EP550_00325 ENOG4105C09 Bile acid EP550_00330 ENOG4107QI1 Mate efflux family protein EP550_00335 ENOG4105EWC Purine nucleoside phosphorylase EP550_00355 ENOG4108RXX maleylacetoacetate isomerase EP550_00365 ENOG4105C85 amino acid EP550_00375 ENOG4105CKI cobalamin synthesis protein EP550_00385 ENOG4105CZE histidine utilization repressor EP550_00390 ENOG41090B9 response to stress EP550_00405 ENOG4105C85 amino acid EP550_00415 ENOG41088SP formiminoglutamate hydrolase EP550_00430 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EP550_00475 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EP550_00485 ENOG4108ZAI phosphatidylglycerophosphatase a EP550_00490 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) EP550_00505 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EP550_00555 ENOG4105KHC sulfurtransferase EP550_00585 ENOG4105BZU Histidine kinase EP550_00590 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EP550_00605 ENOG4107QJQ Mate efflux family protein EP550_00610 ENOG4105CHM Aminotransferase EP550_00615 ENOG4106BRA Membrane EP550_00630 ENOG4105D9M gamma-glutamylcysteine synthetase EP550_00640 ENOG4105CS6 Rhs element vgr protein EP550_00650 ENOG4106I9N Immunoglobulin G binding protein A EP550_00680 ENOG4105IPS esterase EP550_00685 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EP550_00690 ENOG4105EWI Short-chain dehydrogenase reductase Sdr EP550_00695 ENOG4108Z2U ureidoglycolate hydrolase EP550_00705 ENOG41061H0 Monooxygenase EP550_00720 ENOG41084YZ Hydrolase EP550_00750 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) EP550_00755 ENOG4105BZU Histidine kinase EP550_00770 ENOG4105KUZ arsenate reductase EP550_00775 ENOG4105CGK Exodeoxyribonuclease III EP550_00795 ENOG4105D7Z glutathione synthase EP550_00815 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) EP550_00820 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EP550_00825 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EP550_00840 ENOG41063SB peptidase EP550_00845 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) EP550_00850 ENOG4107QSN dihydrolipoamide acetyltransferase EP550_00865 ENOG4105E0K tonB-dependent siderophore receptor EP550_00880 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EP550_00895 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EP550_00915 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP550_00920 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase EP550_00930 ENOG4105D64 Mechanosensitive ion channel EP550_00940 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EP550_00945 ENOG4108W2Y isochorismatase EP550_00955 ENOG4105FBW Monooxygenase EP550_00960 ENOG4108UZX fmn reductase EP550_00975 ENOG4105BZU Histidine kinase EP550_00980 ENOG41062QD Membrane EP550_00985 ENOG4107QN1 sodium solute EP550_00995 ENOG4105C94 Transporter EP550_01005 ENOG4105BZU Histidine kinase EP550_01015 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EP550_01020 ENOG4108WUH Transcriptional regulator, TetR family EP550_01035 ENOG4105RA2 Membrane EP550_01040 ENOG4105DWF phosphomethylpyrimidine kinase EP550_01050 ENOG4107RDB Major Facilitator EP550_01055 ENOG4108UUM single-stranded DNA-binding protein EP550_01065 ENOG4108UMN azlc family EP550_01075 ENOG4105C85 amino acid EP550_01085 ENOG4108JPW Aminotransferase EP550_01090 ENOG4105C26 Dehydrogenase EP550_01100 ENOG4105CHJ isochorismatase hydrolase EP550_01105 ENOG4105EUB pirin domain protein EP550_01150 ENOG4105D94 Major Facilitator Superfamily EP550_01155 ENOG4106NZI LysR family Transcriptional regulator EP550_01175 ENOG4105CPC Aldo Keto reductase EP550_01180 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) EP550_01210 ENOG4105KVH Transcriptional regulator EP550_01220 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein EP550_01285 ENOG4105CUV Homoserine Kinase EP550_01300 ENOG41061CK Antibiotic biosynthesis monooxygenase EP550_01330 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) EP550_01360 ENOG4105CYC Transferase EP550_01370 ENOG4105E0F Histidine kinase EP550_01375 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EP550_01385 ENOG4105CHH sulfate transporter EP550_01390 ENOG4105PDP Short chain dehydrogenase EP550_01400 ENOG4105C5H ABC transporter EP550_01485 ENOG4108IQI permease EP550_01510 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EP550_01525 ENOG4105CJN penicillin-binding protein EP550_01530 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EP550_01535 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) EP550_01550 ENOG4105DHI Methyltransferase EP550_01555 ENOG4108JQC penicillin-binding protein 1A EP550_01580 ENOG4105E4G Type IV pilus EP550_01600 ENOG4105CBC glutamate synthase EP550_01605 ENOG4105BZ8 glutamate synthase EP550_01615 ENOG4108V0P LemA family EP550_01620 ENOG4105HA9 of methanol dehydrogenase type EP550_01635 ENOG4108YSG O-Antigen polymerase EP550_01640 ENOG4108UQY Iron-storage protein EP550_01650 ENOG4105KME endoribonuclease L-psp EP550_01655 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EP550_01670 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) EP550_01720 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) EP550_01735 ENOG4107IFA Lipase (EC 3.1.1.3) EP550_01740 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) EP550_01745 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) EP550_01770 ENOG4108JQ1 Dehydrogenase EP550_01775 ENOG4105CQB FAD linked oxidase domain protein EP550_01785 ENOG4105VRH Antibiotic biosynthesis monooxygenase EP550_01790 ENOG4105NF4 modulator of drug activity EP550_01800 ENOG4107QF7 multi-drug EP550_01820 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EP550_01825 ENOG4105IPI Membrane EP550_01830 ENOG4107SKI cobyrinic Acid a,c-diamide synthase EP550_01860 ENOG4108IQI permease EP550_01865 ENOG4105D82 Glutamate dehydrogenase EP550_01870 ENOG4105C8Y Acetylornithine aminotransferase EP550_01880 ENOG4105C26 Dehydrogenase EP550_01905 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin EP550_01970 ENOG4105W87 Cbs domain EP550_01975 ENOG41067S9 phage shock protein C, PspC EP550_01985 ENOG4105CSU acyl-Coa dehydrogenase EP550_02000 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) EP550_02015 ENOG4105ECY inositol monophosphatase EP550_02020 ENOG4105C1J atp-dependent rna helicase EP550_02030 ENOG4105DHJ ABC, transporter EP550_02035 ENOG4105CY3 ABC transporter, permease EP550_02045 ENOG4105E3I toluene tolerance EP550_02055 ENOG4105D7N magnesium and cobalt transport protein CorA EP550_02060 ENOG4108URH decarboxylase EP550_02070 ENOG4105MJ2 Competence protein EP550_02075 ENOG4105CB5 ATP-dependent DNA helicase recG EP550_02095 ENOG4105C29 acyl-CoA thioesterase EP550_02100 ENOG4105CK2 sodium dicarboxylate symporter EP550_02115 ENOG4105KPV Transcriptional regulator EP550_02125 ENOG4105D7A ATP-binding protein EP550_02130 ENOG4105C28 cystathionine EP550_02135 ENOG41089BK Glutamine amido-transferase EP550_02245 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EP550_02250 ENOG41067V7 50S ribosomal protein L36 EP550_02260 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) EP550_02285 ENOG4105C1G acyl-Coa dehydrogenase EP550_02320 ENOG4105VKU nucleicacid-binding protein EP550_02325 ENOG4105DGW oligopeptidase A EP550_02330 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EP550_02370 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase EP550_02375 ENOG4108K2B transcriptional regulator EP550_02385 ENOG4107S2Z UPF0761 membrane protein EP550_02390 ENOG4105CS1 NAD(P)H quinone oxidoreductase EP550_02420 ENOG4105C9A Phoh family EP550_02430 ENOG4105E4C Lytic transglycosylase catalytic EP550_02460 ENOG4105D6S protein involved in catabolism of external DNA EP550_02465 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EP550_02510 ENOG4105C1G acyl-Coa dehydrogenase EP550_02515 ENOG4108RZE Tetr family transcriptional regulator EP550_02530 ENOG4107QX3 carboxylase EP550_02535 ENOG4105C1G acyl-Coa dehydrogenase EP550_02555 ENOG4105KB2 stringent starvation protein b EP550_02560 ENOG4107MKT Stringent starvation protein a EP550_02565 ENOG4108UJD 30S ribosomal protein S9 EP550_02575 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EP550_02580 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) EP550_02585 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) EP550_02605 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EP550_02615 ENOG4107RZC phospholipase d EP550_02625 ENOG4105UYK outer membrane protein a EP550_02635 ENOG4108KHX Diguanylate cyclase EP550_02680 ENOG4107QN2 dihydrolipoyl dehydrogenase EP550_02690 ENOG4107QPB Beta-lactamase domain protein EP550_02695 ENOG4107U2T alpha beta EP550_02705 ENOG4105NAU thioesterase Superfamily protein EP550_02735 ENOG4105K9H YciI-like protein EP550_02745 ENOG4105DB7 PHP domain protein EP550_02750 ENOG4105FFC UPF0187 protein EP550_02760 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EP550_02765 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EP550_02770 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EP550_02775 ENOG4105VIE preprotein translocase, subunit YajC EP550_02805 ENOG4105BZU Histidine kinase EP550_02810 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) EP550_02815 ENOG4105CM2 brancheD-chain amino acid aminotransferase EP550_02830 ENOG4107BJW polysaccharide deacetylase EP550_02840 ENOG4108PQP glycosyl transferase group 1 EP550_02890 ENOG4105UGU tonB-dependent Receptor EP550_02910 ENOG4108VY7 phosphate-starvation-inducible protein PsiE EP550_02915 ENOG4105CSU acyl-Coa dehydrogenase EP550_02920 ENOG4105CSU acyl-Coa dehydrogenase EP550_02930 ENOG4105EB3 Histidine kinase EP550_02935 ENOG4105E3W Two component transcriptional regulator (Winged helix family EP550_02940 ENOG4105CNG UPF0061 protein EP550_02960 ENOG4108WBT adenosyltransferase EP550_02975 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EP550_03010 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EP550_03030 ENOG4105D3R alkyl hydroperoxide reductase EP550_03045 ENOG4105CSH Transporter EP550_03050 ENOG4108UT2 hemolysin iii EP550_03080 ENOG4105CHU acetyl-coa acetyltransferase EP550_03085 ENOG4108R6W Transcriptional regulator, ARAC family EP550_03095 ENOG4105TW1 Carbohydrate-selective porin OprB EP550_03100 ENOG4105DZG Dehydrogenase EP550_03105 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EP550_03125 ENOG4105CHU acetyl-coa acetyltransferase EP550_03135 ENOG4108WHA ompa motb domain protein EP550_03140 ENOG4105E0Y RtcB Protein EP550_03145 ENOG4108IQI permease EP550_03155 ENOG4105C2W permease EP550_03175 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EP550_03185 ENOG4108VX5 3-methyladenine DNA glycosylase EP550_03195 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP550_03210 ENOG4105T95 Thiol disulfide interChange protein EP550_03215 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) EP550_03225 ENOG4105K78 MarR family Transcriptional regulator EP550_03230 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EP550_03235 ENOG4105KWI UPF0339 protein EP550_03260 ENOG4108UNF response regulator EP550_03265 ENOG4105M3Z response regulator EP550_03270 ENOG4108ZGA chew protein EP550_03275 ENOG4105C8Q Methyl-accepting chemotaxis EP550_03295 ENOG4106HKS Entericidin EcnA/B family EP550_03305 ENOG4105WD1 Membrane EP550_03310 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EP550_03335 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) EP550_03345 ENOG4105EM2 membrane EP550_03350 ENOG4105C2C drug resistance transporter, Bcr CflA EP550_03370 ENOG4105BZG amino acid carrier protein EP550_03375 ENOG4105D78 K07001 NTE family protein EP550_03380 ENOG4105C7B Threonine dehydratase EP550_03425 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EP550_03435 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EP550_03440 ENOG4105DFF Rod shape-determining protein mreb EP550_03445 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EP550_03450 ENOG4105VQ7 Rod shape-determining protein MreD EP550_03455 ENOG4108Z03 MAF-like protein EP550_03460 ENOG4105C03 ribonuclease EP550_03470 ENOG4105D8T Acyltransferase EP550_03480 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein EP550_03490 ENOG4108X0B nad(p)h dehydrogenase (quinone) EP550_03515 ENOG4105CF7 AraC family transcriptional regulator EP550_03535 ENOG4105C85 amino acid EP550_03540 ENOG4105C7F AcnD-accessory protein PrpF EP550_03545 ENOG4105CTB Polyprenyl synthetase EP550_03550 ENOG4105MSB protein, conserved in bacteria EP550_03565 ENOG4105D78 K07001 NTE family protein EP550_03585 ENOG4105DIJ Phosphoethanolamine transferase EP550_03590 ENOG4105XJC Two component transcriptional regulator (Winged helix family EP550_03595 ENOG4105DHQ Histidine kinase EP550_03615 ENOG4108M0I Transcriptional regulator EP550_03635 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) EP550_03655 ENOG4105K8R UPF0145 protein EP550_03660 ENOG4105K8R UPF0145 protein EP550_03665 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EP550_03670 ENOG4105BZS acriflavin resistance protein EP550_03675 ENOG4105C1P efflux transporter, rnd family, mfp subunit EP550_03680 ENOG410841Q phosphoesterase PA-phosphatase related protein EP550_03710 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) EP550_03725 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EP550_03730 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EP550_03735 ENOG4105KVH Transcriptional regulator EP550_03745 ENOG4105CUB amino acid EP550_03760 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) EP550_03765 ENOG41084BA UPF0250 protein EP550_03770 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EP550_03805 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit EP550_03810 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein EP550_03820 ENOG4105E33 succinate dehydrogenase EP550_03835 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 EP550_03840 ENOG4105C7S Dehydrogenase EP550_03845 ENOG4107QN2 dihydrolipoyl dehydrogenase EP550_03855 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EP550_03865 ENOG4105CKW Inner membrane protein yedI EP550_03870 ENOG4105CGZ zinc metallopeptidase EP550_03875 ENOG4105EEQ Na H antiporter EP550_03945 ENOG4105PNM synthesis protein EP550_03960 ENOG41080TK Universal stress protein EP550_03975 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain EP550_03980 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain EP550_03995 ENOG4105HBR Rna-binding protein EP550_04005 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EP550_04010 ENOG4105EEI dihydropteroate synthase EP550_04065 ENOG4105CSH Transporter EP550_04070 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EP550_04075 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EP550_04090 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EP550_04110 ENOG41080IJ Diacylglycerol kinase EP550_04120 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase EP550_04125 ENOG4105BZS acriflavin resistance protein EP550_04140 ENOG4105E4C Lytic transglycosylase catalytic EP550_04165 ENOG4108RRZ Transcription elongation factor GreB EP550_04180 ENOG4105CEY Amp-dependent synthetase and ligase EP550_04225 ENOG4105BZW Glycerate kinase EP550_04230 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit EP550_04235 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EP550_04250 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) EP550_04260 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EP550_04265 ENOG4105C85 amino acid EP550_04275 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EP550_04285 ENOG4105N14 lysine exporter protein LysE YggA EP550_04290 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EP550_04295 ENOG4105BZJ Electron transfer flavoprotein EP550_04300 ENOG4105C10 Electron transfer flavoprotein EP550_04305 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EP550_04340 ENOG4107KET secretion protein, HlyD family EP550_04370 ENOG4105D60 lipoprotein releasing system transmembrane protein EP550_04375 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) EP550_04380 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EP550_04390 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) EP550_04395 ENOG4107R6F Alpha Beta Hydrolase Fold protein EP550_04400 ENOG4108V3E phosphoribosylglycinamide formyltransferase EP550_04410 ENOG4105C02 permease EP550_04470 ENOG4105KCK Peptidoglycan-associated lipoprotein EP550_04475 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) EP550_04485 ENOG4105M8F Biopolymer transport protein exbD tolR EP550_04490 ENOG4105E02 MotA TolQ exbB proton channel EP550_04495 ENOG4107YD3 Thioesterase EP550_04500 ENOG4105CH2 amidohydrolase EP550_04520 ENOG4108ETH Formylglycinamide ribotide synthetase EP550_04525 ENOG4105C2C drug resistance transporter, Bcr CflA EP550_04530 ENOG4105EGD dinuclear metal center protein, YbgI family EP550_04535 ENOG4108UKI Enoyl-CoA hydratase EP550_04550 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EP550_04565 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) EP550_04570 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EP550_04585 ENOG4107R11 Transcriptional regulator EP550_04590 ENOG4108IJ6 ABC transporter EP550_04600 ENOG4108I5D sulfate abc transporter EP550_04610 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EP550_04615 ENOG4105YAZ 4-amino-4-deoxychorismate lyase EP550_04620 ENOG4105HHA aminodeoxychorismate lyase EP550_04635 ENOG4108IYU L-aspartate oxidase EP550_04640 ENOG4105C0H protease EP550_04655 ENOG4105C3F Signal peptidase i EP550_04670 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) EP550_04680 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) EP550_04685 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) EP550_04690 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase EP550_04695 ENOG4105EMU Dehydrogenase EP550_04735 ENOG4105BZU Histidine kinase EP550_04745 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EP550_04755 ENOG4105DTR rard protein EP550_04800 ENOG4107QS8 (LipO)protein EP550_04805 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EP550_04810 ENOG4105EA8 2-Nitropropane dioxygenase EP550_04840 ENOG4107R8N Glycosyl transferase, family 2 EP550_04855 ENOG4105CVP deoxyribo-dipyrimidine photolyase EP550_04860 ENOG4108YZY peptidylprolyl cis-trans isomerase EP550_04865 ENOG4105CEP NADH dehydrogenase EP550_04870 ENOG4105DZ1 carboxypeptidase EP550_04880 ENOG4105E9K Isocitrate dehydrogenase EP550_04885 ENOG4108R99 pseudouridine synthase EP550_04910 ENOG4105CBP Major Facilitator EP550_04915 ENOG4105EGI Transcriptional regulator EP550_04920 ENOG4108ETY sodium dicarboxylate symporter EP550_04925 ENOG4105JAB phenazine biosynthesis protein, phzf family EP550_04955 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) EP550_04970 ENOG4105D3G Pseudouridine synthase EP550_04975 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) EP550_04990 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EP550_05015 ENOG4108JPW Aminotransferase EP550_05020 ENOG4105DY8 decarboxylase EP550_05030 ENOG4105F7P transcriptional regulator AsnC family EP550_05035 ENOG4107RA9 decarboxylase EP550_05040 ENOG4105C85 amino acid EP550_05045 ENOG4105CVA phosphate EP550_05050 ENOG4105C8U phosphate abc transporter EP550_05060 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EP550_05065 ENOG4105ERU peptidase EP550_05080 ENOG4107QTF adenylosuccinate lyase EP550_05100 ENOG4108Z0R Transferase EP550_05105 ENOG4105DZ1 carboxypeptidase EP550_05125 ENOG4108K5P (LipO)protein EP550_05130 ENOG4105EJC lysr family transcriptional regulator EP550_05135 ENOG4105DAN ATP-dependent protease EP550_05150 ENOG4105DHU Bile acid EP550_05170 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EP550_05180 ENOG4105D22 carbon starvation protein EP550_05185 ENOG4105VCD cytoplasmic protein EP550_05220 ENOG4108K8K Transcriptional regulator EP550_05235 ENOG4105C26 Dehydrogenase EP550_05240 ENOG4105C85 amino acid EP550_05245 ENOG4105ETT transcriptional Regulator, LysR family EP550_05250 ENOG4105C94 Transporter EP550_05255 ENOG4105C94 Transporter EP550_05265 ENOG4105C26 Dehydrogenase EP550_05270 ENOG4107QZF nitrite reductase NADPH large subunit EP550_05275 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) EP550_05305 ENOG41060M8 Pfam:PhdYeFM EP550_05310 ENOG4107QNK )-transporter EP550_05315 ENOG4107WEA mandelate racemase muconate lactonizing EP550_05325 ENOG4105J7D transcriptional regulator EP550_05345 ENOG4105C2I pirin domain protein EP550_05355 ENOG4105WWK YheO domain protein EP550_05370 ENOG4105CEY Amp-dependent synthetase and ligase EP550_05385 ENOG4108IPW abc transporter atp-binding protein EP550_05415 ENOG4105C0W non-ribosomal peptide synthetase EP550_05420 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EP550_05425 ENOG4105WQI isochorismatase EP550_05440 ENOG4105BZ1 (ABC) transporter EP550_05460 ENOG4105E4F Isochorismate synthase EP550_05475 ENOG4105NX3 Membrane EP550_05490 ENOG41066YJ Beta-lactamase EP550_05500 ENOG4105EUJ GTP cyclohydrolase i EP550_05510 ENOG4105C7W Xanthine dehydrogenase EP550_05540 ENOG4105CD8 aminopeptidase N EP550_05545 ENOG4105DDQ anthranilate synthase EP550_05855 ENOG4105DIJ Phosphoethanolamine transferase EP550_05890 ENOG4107RAQ aminopeptidase EP550_05895 ENOG4105D0A hydroxylase EP550_05900 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EP550_05920 ENOG4108ZUB Lysine exporter protein (Lyse ygga) EP550_05925 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) EP550_05935 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EP550_05945 ENOG4105W4M Transport-associated protein EP550_05955 ENOG4105E09 nadh pyrophosphatase EP550_05965 ENOG4107RZZ dna polymerase iii epsilon subunit EP550_05970 ENOG4105E9H Lytic Murein transglycosylase EP550_05970 ENOG4105E9H Lytic Murein transglycosylase EP550_05980 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EP550_05985 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EP550_05990 ENOG4108JQ5 ABC transporter EP550_06010 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) EP550_06030 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP550_06045 ENOG4108M3P Membrane EP550_06050 ENOG4105D01 (LipO)protein EP550_06100 ENOG4105F9F transposase EP550_06110 ENOG4105F95 Monooxygenase EP550_06120 ENOG4105C7N Xanthine uracil vitamin C permease EP550_06125 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) EP550_06130 ENOG4105CPW cytochrome b561 EP550_06140 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) EP550_06150 ENOG4105CFH Aspartokinase EP550_06160 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EP550_06170 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis EP550_06185 ENOG4105CPC Aldo Keto reductase EP550_06190 ENOG4107RYR Transcriptional regulator, Crp Fnr family EP550_06195 ENOG4108UKZ OsmC family EP550_06210 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EP550_06240 ENOG4105CD3 dihydroorotase EP550_06245 ENOG4108ZG0 Ompa motb domain protein EP550_06255 ENOG4108TGY Glutathione S-transferase EP550_06260 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) EP550_06270 ENOG4108K3A Glutathione S-transferase EP550_06280 ENOG4108JU3 Alkyl hydroperoxide reductase EP550_06290 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) EP550_06300 ENOG4105D3R alkyl hydroperoxide reductase EP550_06305 ENOG4105CQ7 ATP-dependent helicase EP550_06320 ENOG4105D2S major facilitator superfamily EP550_06325 ENOG4105DKK Benzoate EP550_06330 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase EP550_06335 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein EP550_06340 ENOG4108UKV benzoate 1,2-dioxygenase EP550_06345 ENOG4105FUY alpha subunit EP550_06350 ENOG4108KB2 LysR family Transcriptional regulator EP550_06415 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) EP550_06450 ENOG410829K Lysine exporter protein (Lyse ygga) EP550_06455 ENOG4105VEQ Cold shock protein EP550_06465 ENOG4105II7 pyrroline-5-carboxylate reductase EP550_06500 ENOG4107YPT transcriptional regulator EP550_06515 ENOG4105F9F transposase EP550_06540 ENOG4105C2X Arabinose 5-phosphate isomerase EP550_06545 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase EP550_06555 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA EP550_06560 ENOG4108IUZ ABC transporter EP550_06565 ENOG4105DFG type I secretion outer membrane protein EP550_06605 ENOG4108Z4U Ferredoxin EP550_06625 ENOG4107AQZ Membrane EP550_06630 ENOG4105BZU Histidine kinase EP550_06635 ENOG4105D1S lipid A biosynthesis EP550_06650 ENOG4105D2S major facilitator superfamily EP550_06670 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) EP550_06710 ENOG4105CNA YD repeat protein EP550_06725 ENOG4108WAV Transcriptional regulator EP550_06730 ENOG4105C5A transporter EP550_06750 ENOG4108JIK carboxylase EP550_06755 ENOG4107R4J Chloride channel EP550_06785 ENOG4105R8C Transcriptional regulator EP550_06820 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EP550_06825 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF EP550_06845 ENOG4105MRR Transcriptional regulator (By similarity) EP550_06855 ENOG4108HW3 (ABC) transporter EP550_06935 ENOG4105UYK outer membrane protein a EP550_06945 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EP550_06975 ENOG4105EMY transcriptional regulator EP550_06985 ENOG4107Y2X deaminase EP550_06990 ENOG4105DJ2 Major Facilitator Superfamily EP550_07005 ENOG4105WPN DNA integration recombination invertion protein EP550_07015 ENOG4108Z4X TRANSCRIPTIONal EP550_07030 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EP550_07050 ENOG4105MWK D-amino acid dehydrogenase, small subunit EP550_07075 ENOG4105CZJ Aldehyde dehydrogenase EP550_07080 ENOG4107QTZ amino acid EP550_07085 ENOG4105EJQ L-serine dehydratase EP550_07090 ENOG4105DXM phenylacetic acid degradation protein EP550_07095 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit EP550_07100 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit EP550_07105 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit EP550_07110 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit EP550_07115 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EP550_07120 ENOG4105E39 Enoyl-CoA hydratase EP550_07125 ENOG4108UKI Enoyl-CoA hydratase EP550_07130 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EP550_07135 ENOG4105CHU acetyl-coa acetyltransferase EP550_07140 ENOG4105DZS Phenylacetate-CoA ligase EP550_07145 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein EP550_07155 ENOG4107YAU phenylacetic acid degradation protein EP550_07165 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EP550_07205 ENOG4105VEQ Cold shock protein EP550_07215 ENOG4105CF7 AraC family transcriptional regulator EP550_07295 ENOG4107HP6 Transcriptional regulator EP550_07300 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase EP550_07315 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EP550_07320 ENOG4107RCV ABC transporter, permease EP550_07330 ENOG4107STF Involved in phosphonate degradation (By similarity) EP550_07335 ENOG4108KAZ Involved in phosphonate degradation (By similarity) EP550_07340 ENOG4107RGD Major Facilitator superfamily EP550_07345 ENOG4105C1G acyl-Coa dehydrogenase EP550_07360 ENOG4108UKI Enoyl-CoA hydratase EP550_07365 ENOG4105EA8 2-Nitropropane dioxygenase EP550_07370 ENOG4105EQ0 Major Facilitator superfamily EP550_07380 ENOG4105CHU acetyl-coa acetyltransferase EP550_07385 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EP550_07390 ENOG4105CHR reductase EP550_07395 ENOG4105E39 Enoyl-CoA hydratase EP550_07400 ENOG4105C1G acyl-Coa dehydrogenase EP550_07405 ENOG4107RGD Major Facilitator superfamily EP550_07410 ENOG4107QP7 CoA-transferase subunit A EP550_07415 ENOG4107QNJ CoA-transferase subunit B EP550_07425 ENOG4105EQ0 Major Facilitator superfamily EP550_07435 ENOG4105CSU acyl-Coa dehydrogenase EP550_07450 ENOG4105CC0 LysR family Transcriptional regulator EP550_07465 ENOG4105E39 Enoyl-CoA hydratase EP550_07470 ENOG4107QX3 carboxylase EP550_07475 ENOG4105C1G acyl-Coa dehydrogenase EP550_07480 ENOG4105R8C Transcriptional regulator EP550_07485 ENOG4105CEY Amp-dependent synthetase and ligase EP550_07505 ENOG4105HEI LysR family (Transcriptional regulator EP550_07550 ENOG4105CYX Short-chain dehydrogenase reductase Sdr EP550_07570 ENOG4105KT5 UmuD protein EP550_07580 ENOG4105EW9 transcriptional regulator AsnC family EP550_07590 ENOG4105BZU Histidine kinase EP550_07595 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EP550_07610 ENOG4105EAD ABC transporter EP550_07615 ENOG4108HW4 amino acid AbC transporter EP550_07620 ENOG4105CDA abc transporter atp-binding protein EP550_07625 ENOG4107RP9 extracellular solute-binding protein, family 3 EP550_07630 ENOG4105CT1 (ABC) transporter EP550_07640 ENOG4105EXG Transcriptional regulator EP550_07655 ENOG4105C9B Cysteine desulfurase EP550_07660 ENOG4105ESN nucleotide-binding protein EP550_07665 ENOG4105D7W serine acetyltransferase EP550_07675 ENOG4105CHR reductase EP550_07680 ENOG4105CBN LysR family transcriptional regulator EP550_07685 ENOG4105CYM Glutathione S-transferase EP550_07690 ENOG4108SHQ Glutathione S-transferase EP550_07695 ENOG4105CMU LysR family (Transcriptional regulator EP550_07700 ENOG4105VAW lrga family EP550_07705 ENOG41067MG lrgb family EP550_07725 ENOG4105DXI Major Facilitator superfamily EP550_07735 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase EP550_07740 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) EP550_07755 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase EP550_07760 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EP550_07775 ENOG4108K70 Transcriptional regulator EP550_07780 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EP550_07790 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EP550_07795 ENOG4105C4M (Ubiquinol oxidase) subunit I EP550_07820 ENOG4105C54 Major Facilitator superfamily EP550_07840 ENOG4106FTQ Taurine ABC transporter, periplasmic EP550_07845 ENOG4108IY8 ABC, transporter EP550_07850 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EP550_07855 ENOG4105E2B Taurine dioxygenase EP550_07865 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EP550_07875 ENOG4105CBN LysR family transcriptional regulator EP550_07885 ENOG4105CPN adenine deaminase EP550_07900 ENOG41082YX Transcriptional regulator, arsr family EP550_07905 ENOG4105D6J arsenicaL-resistance protein EP550_07910 ENOG4108KB2 LysR family Transcriptional regulator EP550_07925 ENOG4108JU3 Alkyl hydroperoxide reductase EP550_07950 ENOG4105C0B DNA polymerase III (alpha subunit) EP550_07970 ENOG4105CHM Aminotransferase EP550_07980 ENOG4108V06 Glutathione peroxidase EP550_07985 ENOG4105E7U AraC family transcriptional regulator EP550_08015 ENOG4105ZED uncharacterized protein ygaH EP550_08020 ENOG4108UMN azlc family EP550_08045 ENOG4105C3G gtp-binding protein EP550_08050 ENOG4108UMI ABC transporter, permease EP550_08055 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EP550_08060 ENOG4105D01 (LipO)protein EP550_08065 ENOG4105D01 (LipO)protein EP550_08080 ENOG4107T8P acyl-Coa dehydrogenase EP550_08095 ENOG4105EAD ABC transporter EP550_08100 ENOG4105DRP amino acid AbC transporter EP550_08105 ENOG4105CDA abc transporter atp-binding protein EP550_08115 ENOG4105EW9 transcriptional regulator AsnC family EP550_08130 ENOG41067SE Tetr family transcriptional regulator EP550_08160 ENOG4105CC0 LysR family Transcriptional regulator EP550_08170 ENOG4105ETS cytosine purines uracil thiamine allantoin EP550_08180 ENOG4108IPJ Membrane EP550_08215 ENOG4105GQR Chaperone EP550_08220 ENOG4105X0I Fimbrial EP550_08240 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EP550_08245 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) EP550_08265 ENOG4108HWY Beta-lactamase EP550_08295 ENOG4105CV1 Transketolase (EC 2.2.1.1) EP550_08305 ENOG4108YYC ycei family EP550_08315 ENOG4108T58 Mg2 transport protein CorA EP550_08330 ENOG4105YGK Pfam:UPF0157 EP550_08335 ENOG4105C26 Dehydrogenase EP550_08340 ENOG4105EW9 transcriptional regulator AsnC family EP550_08345 ENOG4105CK7 Sodium proline symporter EP550_08350 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EP550_08360 ENOG4108ZX5 transcriptional regulator EP550_08370 ENOG4105BZ1 (ABC) transporter EP550_08375 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme EP550_08380 ENOG4105XPP Protein of unknown function (DUF1275) EP550_08390 ENOG41080HT Transcriptional regulator, arsr family EP550_08400 ENOG4105EZE Cupin 4 family protein EP550_08405 ENOG4108UHJ MAF-like protein EP550_08425 ENOG4105D2N Aldolase EP550_08430 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EP550_08435 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) EP550_08440 ENOG4105EHM Aminoglycoside phosphotransferase EP550_08445 ENOG4108S0S Nucleotidyl transferase EP550_08455 ENOG4107QJE Chromosome Partitioning Protein EP550_08460 ENOG4105FA0 parb-like partition protein EP550_08475 ENOG4105BZ1 (ABC) transporter EP550_08480 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) EP550_08490 ENOG4107QRG dna polymerase iii EP550_08500 ENOG4105F8V Hydrolase, tatD family EP550_08525 ENOG4108RTD type II secretion system protein K EP550_08545 ENOG4108Z6B deaminase EP550_08560 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) EP550_08565 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) EP550_08585 ENOG4107RN6 Monooxygenase EP550_08595 ENOG4105D6Z AFG1 family ATPase EP550_08665 ENOG4105CDU Replicative dna helicase EP550_08740 ENOG4105EFC phage portal protein HK97 family EP550_08795 ENOG4105E4C Lytic transglycosylase catalytic EP550_08850 ENOG4107QP3 malate synthase g EP550_08860 ENOG4105SG9 biopolymer transport protein, ExbD EP550_08900 ENOG4105DGW oligopeptidase A EP550_08910 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EP550_08930 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase EP550_08945 ENOG4105K4T epimerase EP550_08950 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) EP550_08970 ENOG4108JA2 transcriptioN-repair coupling factor EP550_08980 ENOG4105F8J Adenylate Guanylate cyclase EP550_08985 ENOG4108ZIT Ferredoxin, 2FE-2S EP550_09000 ENOG4108Z4V iron-sulfur cluster assembly EP550_09005 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins EP550_09015 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family EP550_09030 ENOG4105K70 DNA-binding protein EP550_09035 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EP550_09040 ENOG4105E7U AraC family transcriptional regulator EP550_09045 ENOG4105EEF Alkane 1-monooxygenase EP550_09050 ENOG4105C1G acyl-Coa dehydrogenase EP550_09055 ENOG4105C1G acyl-Coa dehydrogenase EP550_09070 ENOG4108Z66 YbaK ebsC protein EP550_09090 ENOG4105DUU IucA IucC family protein EP550_09095 ENOG4105DJU Siderophore biosynthesis protein EP550_09150 ENOG4108YZT Adenosylcobinamide kinase EP550_09155 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) EP550_09175 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EP550_09180 ENOG4107TSN permease EP550_09200 ENOG4105CNM Receptor EP550_09205 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EP550_09240 ENOG4105CJ1 ABC, transporter EP550_09245 ENOG4107QWP ABC-2 type transporter EP550_09250 ENOG4107QWP ABC-2 type transporter EP550_09275 ENOG4105K59 histidine triad (HIT) protein EP550_09305 ENOG4105F2W methyltransferase EP550_09315 ENOG4105C28 cystathionine EP550_09330 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) EP550_09375 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EP550_09380 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) EP550_09405 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EP550_09410 ENOG4107R0V Pyruvate dehydrogenase EP550_09415 ENOG4105CPP Dehydrogenase, E1 component EP550_09430 ENOG4105CHR reductase EP550_09440 ENOG4105FFC UPF0187 protein EP550_09450 ENOG4107QPB Beta-lactamase domain protein EP550_09460 ENOG4108VCT Sulfite exporter TauE/SafE EP550_09475 ENOG4105UEI Transcriptional Regulator AraC Family EP550_09480 ENOG4105KVH Transcriptional regulator EP550_09485 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) EP550_09495 ENOG4105FDP GntR family transcriptional regulator EP550_09510 ENOG4106FTQ Taurine ABC transporter, periplasmic EP550_09515 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EP550_09535 ENOG4105CSH Transporter EP550_09545 ENOG4108IJ0 Aspartate ammonia-lyase EP550_09560 ENOG4107YNJ LysR family Transcriptional regulator EP550_09570 ENOG4105CHU acetyl-coa acetyltransferase EP550_09575 ENOG4105CRW Short chain fatty acid transporter EP550_09580 ENOG4107QNJ CoA-transferase subunit B EP550_09590 ENOG4108M0I Transcriptional regulator EP550_09600 ENOG4105CY2 Citrate transporter EP550_09605 ENOG4105DTD Dehydrogenase EP550_09610 ENOG4105CF7 AraC family transcriptional regulator EP550_09615 ENOG4105D2S major facilitator superfamily EP550_09625 ENOG4105CHR reductase EP550_09650 ENOG4105F57 Anthranilate dioxygenase reductase EP550_09655 ENOG4108YS2 small subunit EP550_09660 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit EP550_09665 ENOG4105F4R Transcriptional regulator mode EP550_09670 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EP550_09675 ENOG4105E0C molybdate abc transporter EP550_09680 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) EP550_09685 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase EP550_09690 ENOG4105WQI isochorismatase EP550_09700 ENOG4107T31 5'-nucleotidase EP550_09735 ENOG4108IGT Dipeptidase EP550_09770 ENOG4107RZC phospholipase d EP550_09820 ENOG4105X0I Fimbrial EP550_09840 ENOG4105CJP fad dependent oxidoreductase EP550_09860 ENOG4105CT3 Monooxygenase EP550_09870 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EP550_09875 ENOG4105BZS acriflavin resistance protein EP550_09880 ENOG4105C1P efflux transporter, rnd family, mfp subunit EP550_09885 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EP550_09890 ENOG4105E0F Histidine kinase EP550_09895 ENOG4108821 RND type efflux pump EP550_09900 ENOG4108R6W Transcriptional regulator, ARAC family EP550_09915 ENOG4108BAS reductase EP550_09970 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) EP550_10010 ENOG4108UAJ Transcriptional regulator EP550_10090 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EP550_10110 ENOG4105E0A ABC, transporter EP550_10115 ENOG4105EHG Permease protein EP550_10125 ENOG4105DQ4 alcohol dehydrogenase EP550_10140 ENOG4105CF7 AraC family transcriptional regulator EP550_10145 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EP550_10155 ENOG4105EXW epimerase dehydratase EP550_10160 ENOG4105DDW LysR family Transcriptional regulator EP550_10170 ENOG4105C01 Dihydroxy-acid dehydratase EP550_10175 ENOG4105CZJ Aldehyde dehydrogenase EP550_10190 ENOG4105CW7 secretion protein, HlyD family EP550_10210 ENOG4105JSC dimethylmenaquinone methyltransferase EP550_10215 ENOG4108JQ1 Dehydrogenase EP550_10240 ENOG4106P55 Transcriptional regulator EP550_10255 ENOG4105FDP GntR family transcriptional regulator EP550_10285 ENOG4105CKT filamentous hemagglutinin EP550_10290 ENOG4105D5K Hemolysin activator protein EP550_10305 ENOG4105CH2 amidohydrolase EP550_10315 ENOG4105CKD glutathione-regulated potassium-efflux system protein EP550_10320 ENOG4105D8V Glucose sorbosone dehydrogenase EP550_10325 ENOG4105EJC lysr family transcriptional regulator EP550_10330 ENOG4105CHJ isochorismatase hydrolase EP550_10350 ENOG4107Z3H Transcriptional regulator, TetR family EP550_10380 ENOG4105NAE bifunctional deaminase-reductase domain protein EP550_10390 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP550_10395 ENOG4105K56 Transcriptional regulator EP550_10420 ENOG4105CH6 catalase EP550_10435 ENOG4107RGH Aldehyde dehydrogenase EP550_10450 ENOG41062QD Membrane EP550_10460 ENOG4108JU7 Transcriptional regulator EP550_10465 ENOG4105CHR reductase EP550_10470 ENOG4105C1G acyl-Coa dehydrogenase EP550_10490 ENOG4105CZJ Aldehyde dehydrogenase EP550_10510 ENOG4107EJG GntR family transcriptional regulator EP550_10520 ENOG4108KB2 LysR family Transcriptional regulator EP550_10525 ENOG4105DTQ mandelate racemase muconate lactonizing EP550_10530 ENOG4105NN7 muconolactone delta-isomerase EP550_10540 ENOG4107QP7 CoA-transferase subunit A EP550_10545 ENOG4107QNJ CoA-transferase subunit B EP550_10550 ENOG4105CHU acetyl-coa acetyltransferase EP550_10555 ENOG4105F2Z 3-oxoadipate enol-lactonase EP550_10565 ENOG4105C26 Dehydrogenase EP550_10575 ENOG4105F11 amine oxidase EP550_10595 ENOG4105CHR reductase EP550_10605 ENOG4105FUY alpha subunit EP550_10625 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EP550_10635 ENOG4105DNH Major Facilitator EP550_10660 ENOG4105C1G acyl-Coa dehydrogenase EP550_10665 ENOG4108PTX LysR family Transcriptional regulator EP550_10670 ENOG4107HP6 Transcriptional regulator EP550_10685 ENOG4105MD1 YeeE YedE family protein EP550_10695 ENOG4105DZG Dehydrogenase EP550_10700 ENOG4105TW1 Carbohydrate-selective porin OprB EP550_10705 ENOG4106JPM 3-dehydroshikimate dehydratase EP550_10710 ENOG4105FF2 Type I DHQase EP550_10715 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha EP550_10720 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta EP550_10725 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EP550_10730 ENOG4105D2S major facilitator superfamily EP550_10735 ENOG4105F2Z 3-oxoadipate enol-lactonase EP550_10740 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase EP550_10745 ENOG4105CHU acetyl-coa acetyltransferase EP550_10750 ENOG4107QNJ CoA-transferase subunit B EP550_10755 ENOG4107QP7 CoA-transferase subunit A EP550_10765 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) EP550_10770 ENOG4107VMU Membrane EP550_10815 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EP550_10830 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EP550_10840 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EP550_10845 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) EP550_10875 ENOG4105C7B Threonine dehydratase EP550_10885 ENOG4105CZN Potassium uptake protein EP550_10890 ENOG4105HDD phospholipase EP550_10900 ENOG4105E0K tonB-dependent siderophore receptor EP550_10915 ENOG4105PV3 Inner membrane protein yqiJ EP550_10920 ENOG4105F9F transposase EP550_10935 ENOG4105C4M (Ubiquinol oxidase) subunit I EP550_10940 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EP550_10960 ENOG41068P6 UPF0319 protein EP550_10970 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EP550_10995 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EP550_11000 ENOG4105C8Y Acetylornithine aminotransferase EP550_11005 ENOG4105M2J Glutaredoxin EP550_11015 ENOG4105CC0 LysR family Transcriptional regulator EP550_11020 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EP550_11025 ENOG4105CWM branched-chain amino acid transport system II carrier protein EP550_11050 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EP550_11055 ENOG4105DE4 1-phosphofructokinase EP550_11060 ENOG4105DM4 PTS System EP550_11080 ENOG4105BZU Histidine kinase EP550_11090 ENOG4105D8V Glucose sorbosone dehydrogenase EP550_11095 ENOG4108RAV Conserved protein EP550_11100 ENOG4105CHH sulfate transporter EP550_11115 ENOG4105C85 amino acid EP550_11125 ENOG4105F7P transcriptional regulator AsnC family EP550_11150 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 EP550_11155 ENOG4105VEJ Heat shock protein EP550_11165 ENOG4105Y3E Modulates RecA activity (By similarity) EP550_11180 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EP550_11205 ENOG4105DZP Membrane-associated zinc metalloprotease EP550_11215 ENOG4105KNE Phosphatidate cytidylyltransferase EP550_11220 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) EP550_11245 ENOG4105CUX Signal transduction histidine kinase EP550_11250 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EP550_11310 ENOG4105CMR udp-glucose 4-epimerase EP550_11315 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) EP550_11335 ENOG4105T38 integral membrane protein EP550_11340 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EP550_11350 ENOG4105CVM Molybdenum cofactor synthesis domain protein EP550_11355 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EP550_11370 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EP550_11390 ENOG4108IFG nitrite reductase, (NAD(P)H) EP550_11395 ENOG4107QZF nitrite reductase NADPH large subunit EP550_11405 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EP550_11430 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein EP550_11435 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EP550_11445 ENOG4105D8G Major Facilitator superfamily EP550_11745 ENOG4105CBC glutamate synthase EP550_11775 ENOG4105C0A alcohol dehydrogenase EP550_11785 ENOG4105HSS phospholipase C EP550_11790 ENOG4107QMP dna polymerase iii subunits gamma and tau EP550_11815 ENOG4105CHR reductase EP550_11820 ENOG4105CHU acetyl-coa acetyltransferase EP550_11830 ENOG4105C5Q Transcriptional regulator EP550_11835 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EP550_11840 ENOG4108NIW Leucine export protein LeuE EP550_11845 ENOG4105EW9 transcriptional regulator AsnC family EP550_11850 ENOG4105DKK Benzoate EP550_11860 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EP550_11875 ENOG41081QV Universal stress protein EP550_11880 ENOG4105C5H ABC transporter EP550_11900 ENOG4105CNM Receptor EP550_11935 ENOG4105CUY Mechanosensitive ion channel EP550_11945 ENOG4105R8C Transcriptional regulator EP550_11960 ENOG4105EW9 transcriptional regulator AsnC family EP550_11965 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) EP550_11975 ENOG4105EMU Dehydrogenase EP550_11985 ENOG4105CD8 aminopeptidase N EP550_12005 ENOG4105F4I Transcriptional regulator EP550_12015 ENOG4107QUV Domain protein EP550_12020 ENOG4105C0A alcohol dehydrogenase EP550_12030 ENOG4107RR1 TRANSCRIPTIONal EP550_12040 ENOG4107R55 ethanolamine transporter EP550_12045 ENOG4105CPD ethanolamine ammonia-lyase EP550_12050 ENOG4107FQ9 ethanolamine ammonia-lyase EP550_12055 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EP550_12080 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) EP550_12090 ENOG4108RCM Nitroreductase EP550_12095 ENOG4108TZV Membrane EP550_12100 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EP550_12110 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) EP550_12115 ENOG4105K8N protein family UPF0079, ATPase EP550_12150 ENOG4105DZ2 Transcriptional regulator EP550_12165 ENOG4105F27 Major Facilitator EP550_12170 ENOG4105EYW Ion transport protein EP550_12180 ENOG4107QIJ Aconitate hydratase 2 EP550_12200 ENOG4105CFU surface antigen EP550_12205 ENOG4107S74 Lysophospholipid transporter LplT EP550_12220 ENOG4105CFQ glutamine synthetase EP550_12225 ENOG4105EEX Two component transcriptional regulator (Winged helix family EP550_12230 ENOG4105C08 Histidine kinase EP550_12240 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EP550_12245 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EP550_12265 ENOG4105D06 uba thif-type nad fad binding protein EP550_12270 ENOG4108MEJ flavin reductase domain protein EP550_12280 ENOG4105C1G acyl-Coa dehydrogenase EP550_12295 ENOG4105GVF (ABC) transporter EP550_12300 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EP550_12305 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EP550_12320 ENOG4105CC0 LysR family Transcriptional regulator EP550_12340 ENOG4105DEN Luciferase family EP550_12350 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD EP550_12355 ENOG4105CND Glycosyl transferase, family 2 EP550_12360 ENOG4107BJW polysaccharide deacetylase EP550_12385 ENOG4105E2S oxidase) subunit II EP550_12390 ENOG4105BZ9 Cytochrome C oxidase, subunit I EP550_12395 ENOG4105CCU oxidase (Subunit III) EP550_12400 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) EP550_12425 ENOG4105CDU Replicative dna helicase EP550_12430 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EP550_12480 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) EP550_12485 ENOG4105DC1 bifunctional purine biosynthesis protein purh EP550_12490 ENOG4105C12 Phosphoribosylglycinamide synthetase EP550_12500 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EP550_12505 ENOG4108UMI ABC transporter, permease EP550_12510 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EP550_12520 ENOG4105CK2 sodium dicarboxylate symporter EP550_12560 ENOG4105DY2 Paraquat-inducible protein b EP550_12565 ENOG4105F1S paraquat-inducible protein a EP550_12580 ENOG4105CEB Aspartate aminotransferase EP550_12605 ENOG4105CSH Transporter EP550_12660 ENOG4105JXH GntR family transcriptional regulator EP550_12670 ENOG4105D6U Sodium Glutamate Symporter EP550_12700 ENOG4105H4F exported protein EP550_12735 ENOG4105C26 Dehydrogenase EP550_12740 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EP550_12745 ENOG4105EVZ LysR family transcriptional regulator EP550_12770 ENOG4105D9P serine threonine protein kinase EP550_12795 ENOG4105VCC 30S ribosomal protein S21 EP550_12800 ENOG4105KTH gatB Yqey EP550_12805 ENOG4105ERG peptidase m48, ste24p EP550_12810 ENOG4105C5I Dehydrogenase EP550_12825 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase EP550_12860 ENOG41069NU Nitroreductase EP550_12870 ENOG4105C1J atp-dependent rna helicase EP550_12875 ENOG4105VEQ Cold shock protein EP550_12885 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EP550_12890 ENOG4105M08 Membrane EP550_12920 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) EP550_12925 ENOG4105CIN aminoacyl-histidine dipeptidase EP550_12935 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase EP550_12940 ENOG4105CQC Prephenate dehydratase EP550_12945 ENOG4105NIV Esterase EP550_12950 ENOG4105C1G acyl-Coa dehydrogenase EP550_12955 ENOG4105CK2 sodium dicarboxylate symporter EP550_12965 ENOG4107QYG anthranilate phosphoribosyltransferase EP550_12970 ENOG4105VUT cytoplasmic protein EP550_12975 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) EP550_12980 ENOG4105BZ4 penicillin-binding protein EP550_12990 ENOG4105M6F mutator MutT protein EP550_13000 ENOG4105DHQ Histidine kinase EP550_13005 ENOG4105XJC Two component transcriptional regulator (Winged helix family EP550_13015 ENOG4107QHF type ii secretion system protein e EP550_13025 ENOG4108R96 Methyltransferase, YaeB family EP550_13030 ENOG4105DP0 ferredoxin-NADP reductase EP550_13035 ENOG4105JAB phenazine biosynthesis protein, phzf family EP550_13040 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EP550_13045 ENOG4105CFP Peptidase U32 EP550_13050 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EP550_13060 ENOG4108JEH abc transporter atp-binding protein EP550_13065 ENOG4106YG3 ABC transporter EP550_13070 ENOG4105DSP amino acid AbC transporter EP550_13075 ENOG4105E89 ABC transporter EP550_13085 ENOG4105ENT Efflux transporter rnd family, mfp subunit EP550_13095 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EP550_13130 ENOG4105DA5 (ABC) transporter EP550_13135 ENOG4105E3A (ABC) transporter EP550_13150 ENOG4105CNI cell division protein FtsW EP550_13155 ENOG4105CVE Lytic murein transglycosylase EP550_13195 ENOG4105CE9 30S ribosomal protein S2 EP550_13200 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EP550_13210 ENOG4107RNU major facilitator superfamily MFS_1 EP550_13220 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) EP550_13225 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EP550_13230 ENOG4107QPN acyl-Coa dehydrogenase EP550_13245 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) EP550_13250 ENOG4105SYT Methylenetetrahydrofolate reductase EP550_13255 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EP550_13260 ENOG4105BZU Histidine kinase EP550_13265 ENOG4105C6K Malic enzyme EP550_13275 ENOG4105C0H protease EP550_13280 ENOG4107QNR UPF0135 protein EP550_13285 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EP550_13320 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) EP550_13330 ENOG4105C5F glutamine synthetase EP550_13335 ENOG4105DUX Transporter EP550_13345 ENOG4105DFP Integrase EP550_13430 ENOG4105UPP uncharacterized protein ydcA EP550_13730 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EP550_13755 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EP550_13765 ENOG4105D82 Glutamate dehydrogenase EP550_13770 ENOG4108R3D Electron transport complex EP550_13775 ENOG4105CSM endonuclease III EP550_13800 ENOG4105CJN penicillin-binding protein EP550_13805 ENOG4106H78 methyltransferase EP550_13820 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) EP550_13830 ENOG4105CQM Urea amidohydrolase subunit alpha EP550_13860 ENOG4107RET Isocitrate lyase EP550_13870 ENOG4105C37 (CBS) domain EP550_13880 ENOG4105D4T Citrate transporter EP550_13895 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) EP550_13910 ENOG4108MRJ EP550_13930 ENOG4105VCQ rubredoxin EP550_13935 ENOG4107QZF nitrite reductase NADPH large subunit EP550_13945 ENOG4105C5Q Transcriptional regulator EP550_13970 ENOG4107U91 Rhomboid family EP550_13975 ENOG4105CV6 ABC transporter, permease EP550_13980 ENOG4108I0Y (ABC) transporter EP550_13985 ENOG4108UJV acyl-CoA thioesterase i EP550_14005 ENOG4107RNH Outer membrane receptor FepA EP550_14020 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) EP550_14025 ENOG4105E6M Sulphatase-modifying factor protein EP550_14045 ENOG4105CJ3 phosphate transporter EP550_14050 ENOG4105C3R Methionine synthase EP550_14065 ENOG4105CSP Major Facilitator Superfamily EP550_14075 ENOG4108PZW LysR family Transcriptional regulator EP550_14090 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) EP550_14095 ENOG4105EU0 Major facilitator Superfamily EP550_14100 ENOG4108R6W Transcriptional regulator, ARAC family EP550_14105 ENOG4105CSV Glutaminase EP550_14110 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EP550_14115 ENOG4105CSH Transporter EP550_14125 ENOG4105C7K acetolactate synthase EP550_14140 ENOG4105CHR reductase EP550_14145 ENOG4108MXF Alpha Beta Hydrolase EP550_14155 ENOG4105DJB Major Facilitator Superfamily EP550_14160 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase EP550_14170 ENOG4105CHR reductase EP550_14190 ENOG41069M3 Transcriptional regulator EP550_14205 ENOG4106YT9 Enoyl-CoA hydratase EP550_14215 ENOG4105CND Glycosyl transferase, family 2 EP550_14220 ENOG4107BJW polysaccharide deacetylase EP550_14230 ENOG4108VWS Yaeq family EP550_14240 ENOG4105CKI cobalamin synthesis protein EP550_14260 ENOG4105C94 Transporter EP550_14265 ENOG4105C94 Transporter EP550_14270 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) EP550_14295 ENOG4107QK5 Homocysteine s-methyltransferase EP550_14300 ENOG4105D5Q Arginine ornithine antiporter EP550_14360 ENOG4108SF5 RNA Polymerase EP550_14370 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EP550_14375 ENOG4105C54 Major Facilitator superfamily EP550_14425 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) EP550_14430 ENOG4105C0R drug resistance transporter emrb qaca subfamily EP550_14435 ENOG4105CW7 secretion protein, HlyD family EP550_14440 ENOG4108VUY thioesterase Superfamily protein EP550_14445 ENOG4105D52 delta-aminolevulinic acid dehydratase EP550_14450 ENOG4105MWK D-amino acid dehydrogenase, small subunit EP550_14455 ENOG4105ECP epimerase EP550_14475 ENOG4107RH8 nuclease SbcCD subunit D EP550_14480 ENOG4105EYH Exonuclease EP550_14485 ENOG4105DFA alanine racemase domain protein EP550_14490 ENOG4105CZX twitching motility protein EP550_14495 ENOG4105CZX twitching motility protein EP550_14500 ENOG41090R7 Ferric uptake EP550_14530 ENOG4105E7A Glutamine amidotransferase EP550_14545 ENOG4107QKV phosphomannomutase EP550_14555 ENOG4105C4R Atp-dependent dna helicase EP550_14560 ENOG4108ZG0 Ompa motb domain protein EP550_14565 ENOG4106HNH Acyl-transferase EP550_14580 ENOG4107QMS site-determining protein EP550_14620 ENOG4105CNU cell division protein FtsK EP550_14625 ENOG4105C3M thioredoxin reductase EP550_14630 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) EP550_14640 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EP550_14685 ENOG4108YXA Membrane EP550_14690 ENOG4105EUB pirin domain protein EP550_14700 ENOG4105C4K Nad synthetase EP550_14715 ENOG4105E3J oxidoreductase EP550_14720 ENOG4105C26 Dehydrogenase EP550_14725 ENOG4105DVW rieske (2Fe-2S) EP550_14735 ENOG4105C94 Transporter EP550_14740 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EP550_14745 ENOG4105EJC lysr family transcriptional regulator EP550_14765 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EP550_14785 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EP550_14790 ENOG4105C34 Pseudouridine synthase EP550_14795 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane EP550_14800 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EP550_14815 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) EP550_14835 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EP550_14865 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EP550_14875 ENOG4105DWF phosphomethylpyrimidine kinase EP550_14880 ENOG4109066 lysm domain bon superfamily protein EP550_14890 ENOG4105CHR reductase EP550_14895 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EP550_14905 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein EP550_14910 ENOG4108BPE -transporting atpase EP550_14915 ENOG4107RTD sua5 ycio yrdc ywlc family protein EP550_14920 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) EP550_14925 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) EP550_14930 ENOG4105FE9 pseudouridine synthase EP550_14940 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EP550_14945 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) EP550_14955 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EP550_14960 ENOG4108K4C ec 3.1.3.12 EP550_14965 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase EP550_14970 ENOG4106UW1 Major Facilitator superfamily EP550_14990 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) EP550_15000 ENOG4105HF0 Membrane EP550_15015 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY EP550_15025 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) EP550_15085 ENOG4105D1F ATP-binding protein EP550_15095 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) EP550_15125 ENOG4105K6H D-cysteine desulfhydrase EP550_15130 ENOG4105CBX hi0933 family EP550_15155 ENOG4105DP0 ferredoxin-NADP reductase EP550_15160 ENOG4105DUM transcriptional regulator, lysR family EP550_15180 ENOG4105C8S subunit m EP550_15185 ENOG4105D65 subunit l EP550_15195 ENOG4107UFS subunit j EP550_15210 ENOG4108IEH NADH dehydrogenase subunit g EP550_15215 ENOG4107QIZ NADH dehydrogenase EP550_15220 ENOG4105GKE subunit e EP550_15240 ENOG4105BZU Histidine kinase EP550_15250 ENOG4105E0F Histidine kinase EP550_15255 ENOG4107EXC regulatoR EP550_15265 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EP550_15275 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EP550_15285 ENOG4105EB3 Histidine kinase EP550_15355 ENOG4105DZG Dehydrogenase EP550_15385 ENOG4105JAB phenazine biosynthesis protein, phzf family EP550_15400 ENOG4105F9F transposase EP550_15420 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) EP550_15425 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) EP550_15435 ENOG4105ETT transcriptional Regulator, LysR family EP550_15455 ENOG4105CH2 amidohydrolase EP550_15465 ENOG4106P55 Transcriptional regulator EP550_15485 ENOG4106P55 Transcriptional regulator EP550_15490 ENOG4107EFR Flavocytochrome c EP550_15500 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EP550_15505 ENOG4107RGD Major Facilitator superfamily EP550_15510 ENOG4105C1G acyl-Coa dehydrogenase EP550_15515 ENOG4105ETT transcriptional Regulator, LysR family EP550_15550 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) EP550_15555 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) EP550_15560 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EP550_15575 ENOG4105VR0 copper resistance EP550_15580 ENOG4105E3B Multicopper oxidase EP550_15590 ENOG4108HCJ Hydrolase EP550_15595 ENOG4105DJV ribulose-phosphate 3-epimerase EP550_15620 ENOG41072GX Peptidase M22 Glycoprotease EP550_15625 ENOG4108Z0R Transferase EP550_15685 ENOG4105CRQ synthase (Component I) EP550_15695 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) EP550_15700 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) EP550_15705 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) EP550_15775 ENOG4105K56 Transcriptional regulator EP550_15780 ENOG4108ZHJ Organic hydroperoxide resistance protein EP550_15785 ENOG4107QHF type ii secretion system protein e EP550_15805 ENOG4105C2M dna polymerase I EP550_15810 ENOG4108VIA integral membrane protein EP550_15815 ENOG4105II7 pyrroline-5-carboxylate reductase EP550_15820 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) EP550_15830 ENOG4105C9X ppx gppa phosphatase EP550_15840 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EP550_15860 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) EP550_15885 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) EP550_15900 ENOG4105W39 Membrane EP550_15905 ENOG4105CYM Glutathione S-transferase EP550_15925 ENOG4105CEY Amp-dependent synthetase and ligase EP550_15930 ENOG4105N42 UPF0307 protein EP550_15935 ENOG41080Z8 PHOSPHOCARRIER protein EP550_15955 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EP550_15960 ENOG4105DJ0 Poly(A) Polymerase EP550_15965 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein EP550_15970 ENOG4105DXN mazG family EP550_15980 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EP550_15995 ENOG4105C6T cysteine synthase EP550_16000 ENOG4105BZU Histidine kinase EP550_16005 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase EP550_16010 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EP550_16015 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EP550_16030 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EP550_16035 ENOG4105W8H transhydrogenase (subunit alpha EP550_16040 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EP550_16070 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EP550_16080 ENOG4107RSM transcriptional regulator EP550_16090 ENOG4105CUZ uba thif-type nad fad binding protein EP550_16100 ENOG4107QM5 aconitate hydratase EP550_16105 ENOG4105F8V Hydrolase, tatD family EP550_16120 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) EP550_16145 ENOG4105BZU Histidine kinase EP550_16155 ENOG4108ZP8 Acetolactate synthase small subunit EP550_16160 ENOG4105C7K acetolactate synthase EP550_16185 ENOG4105DJY efflux transporter, rnd family, mfp subunit EP550_16190 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EP550_16195 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EP550_16200 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH EP550_16210 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) EP550_16215 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) EP550_16225 ENOG4105VW4 glutaredoxin 3 EP550_16245 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EP550_16250 ENOG4105C2D reductase EP550_16260 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EP550_16290 ENOG4105C84 Histidine ammonia-lyase EP550_16305 ENOG4105CEY Amp-dependent synthetase and ligase EP550_16320 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) EP550_16340 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EP550_16360 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) EP550_16380 ENOG4105WVQ Fe-S assembly protein IscX EP550_16395 ENOG4105CN1 protease EP550_16410 ENOG4106HB6 Alpha beta hydrolase EP550_16420 ENOG4105C26 Dehydrogenase EP550_16425 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EP550_16430 ENOG4105C6Z Gluconate EP550_16435 ENOG4108UHU Aldolase EP550_16440 ENOG4105C01 Dihydroxy-acid dehydratase EP550_16450 ENOG4108HWY Beta-lactamase EP550_16460 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) EP550_16465 ENOG4108DNC Involved in acetate metabolism (By similarity) EP550_16470 ENOG4107GFK fumarate EP550_16490 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EP550_16500 ENOG4108ESX Receptor EP550_16510 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) EP550_16520 ENOG4105DWV Homoserine O-trans-acetylase EP550_16620 ENOG4105CIY formyltetrahydrofolate deformylase EP550_16630 ENOG4107RGH Aldehyde dehydrogenase EP550_16635 ENOG4105KDC 50s ribosomal protein l28 EP550_16640 ENOG4105W0E 50S ribosomal protein L33 EP550_16645 ENOG4105CKD glutathione-regulated potassium-efflux system protein EP550_16665 ENOG4105VFU Rna-binding protein EP550_16670 ENOG4105C4R Atp-dependent dna helicase EP550_16685 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EP550_16695 ENOG4105KVH Transcriptional regulator EP550_16705 ENOG41069P5 Protein slyX homolog EP550_16710 ENOG4105C5H ABC transporter EP550_16715 ENOG4105N14 lysine exporter protein LysE YggA EP550_16720 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase EP550_16730 ENOG4105CK2 sodium dicarboxylate symporter EP550_16785 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EP550_16810 ENOG4105DUM transcriptional regulator, lysR family EP550_16835 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase EP550_16850 ENOG4108W5M transcriptional regulator EP550_16870 ENOG4105D29 Helix-turn-helix type 11 domain protein EP550_16875 ENOG4107XGZ Hydrolase EP550_16880 ENOG4105EI2 Pseudouridine synthase EP550_16890 ENOG4105C03 ribonuclease EP550_16905 ENOG4105CBN LysR family transcriptional regulator EP550_16910 ENOG4105EMU Dehydrogenase EP550_16915 ENOG4105CSA Coproporphyrinogen iii oxidase EP550_16925 ENOG4107QI1 Mate efflux family protein EP550_16935 ENOG4107T8P acyl-Coa dehydrogenase EP550_16980 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) EP550_16985 ENOG4105C5X domain protein EP550_17000 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EP550_17010 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase EP550_17015 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) EP550_17020 ENOG4108JU5 Magnesium and cobalt efflux protein EP550_17025 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) EP550_17030 ENOG4108Z7R Chaperone CsaA EP550_17040 ENOG4108VAU general secretion pathway protein G EP550_17045 ENOG4105D7Q type ii secretion system EP550_17050 ENOG4105C25 Primosomal protein n' EP550_17055 ENOG4105CKD glutathione-regulated potassium-efflux system protein EP550_17060 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) EP550_17070 ENOG4105DVC DnaJ domain protein EP550_17075 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) EP550_17080 ENOG4107QUT magnesium and cobalt transport protein CorA EP550_17100 ENOG4107QYX exodeoxyribonuclease v alpha EP550_17105 ENOG4107QKA exodeoxyribonuclease V beta EP550_17110 ENOG4105DSY exodeoxyribonuclease V, gamma EP550_17120 ENOG4105CSR polyphosphate kinase 2 EP550_17130 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) EP550_17145 ENOG41061H0 Monooxygenase EP550_17150 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase EP550_17165 ENOG4105D65 subunit l EP550_17170 ENOG4108ZE9 Monovalent cation H antiporter subunit C EP550_17175 ENOG4107R4Z monovalent cation h antiporter subunit d EP550_17180 ENOG4105SC1 monovalent cation H antiporter subunit E EP550_17185 ENOG4105W4C monovalent cation H antiporter subunit F EP550_17190 ENOG4105KJM monovalent cation h antiporter subunit g EP550_17205 ENOG4105CHV Transcription elongation factor NusA EP550_17230 ENOG4107EJC Preprotein translocase subunit SecG EP550_17240 ENOG4107QHF type ii secretion system protein e EP550_17255 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EP550_17265 ENOG4105C2N RNA methyltransferase TrmH family group 3 EP550_17280 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EP550_17290 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) EP550_17320 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EP550_17325 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EP550_17395 ENOG4107ZXU DSBA oxidoreductase EP550_17410 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) EP550_17425 ENOG4105D3Y Na H antiporter EP550_17430 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EP550_17485 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EP550_17490 ENOG4105PM1 preprotein translocase subunit SecE EP550_17530 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EP550_17535 ENOG4105TV9 FHA Domain-Containing protein EP550_17540 ENOG4105GVR general secretion pathway protein D EP550_17555 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS EP550_17580 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) EP550_17585 ENOG4108NEV two component transcriptional regulator, LytTR family EP550_17590 ENOG4108HRK Histidine kinase EP550_17605 ENOG4108UTW Plays a role in the regulation of phosphate uptake EP550_17610 ENOG4105DFG type I secretion outer membrane protein EP550_17615 ENOG4108RNG Permease of the drug metabolite transporter EP550_17640 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EP550_17645 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EP550_17650 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) EP550_17655 ENOG4105CNI cell division protein FtsW EP550_17670 ENOG4105CE1 Ferrous iron transport protein b EP550_17680 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EP550_17685 ENOG4105T95 Thiol disulfide interChange protein EP550_17690 ENOG4105D6E homoserine dehydrogenase EP550_17700 ENOG41061WM D-Alanyl-D-Alanine EP550_17710 ENOG4107TUY Histidine kinase EP550_17715 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EP550_17720 ENOG4105CN1 protease EP550_17725 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) EP550_17730 ENOG4108K5H permease YjgP YjgQ family protein EP550_17770 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EP550_17780 ENOG4105BZU Histidine kinase EP550_17795 ENOG4105C0P Mg chelatase subunit ChlI EP550_17805 ENOG4108R0M Aminoglycoside EP550_17850 ENOG4105CHH sulfate transporter EP550_17895 ENOG4105C0P Mg chelatase subunit ChlI EP550_17900 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EP550_17910 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EP550_17925 ENOG4105EPF Outer membrane porin EP550_17930 ENOG4105F0N pyrophosphate phospho-hydrolase EP550_17945 ENOG4105CEY Amp-dependent synthetase and ligase EP550_17950 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EP550_17955 ENOG41079KZ Major Facilitator Superfamily EP550_17960 ENOG4105EN6 Membrane EP550_17965 ENOG4105K5B UPF0225 protein EP550_17970 ENOG4105EE5 Membrane protein terC EP550_17975 ENOG4108URH decarboxylase EP550_17980 ENOG4105C0R drug resistance transporter emrb qaca subfamily EP550_17990 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EP550_18005 ENOG4105CCT upf0313 protein EP550_18025 ENOG4105CS1 NAD(P)H quinone oxidoreductase EP550_18035 ENOG4105C6T cysteine synthase EP550_18070 ENOG4105Y7M Transcriptional regulator, TetR family EP550_18105 ENOG4105C79 DNA protecting protein DprA EP550_18120 ENOG4108IND Tetr family transcriptional regulator EP550_18125 ENOG4107RTG Major Facilitator superfamily EP550_18135 ENOG4108V06 Glutathione peroxidase EP550_18145 ENOG41090VV Protein of unknown function (DUF2846) EP550_18180 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) EP550_18205 ENOG4105FDK ABC transporter EP550_18210 ENOG4105FAV ABC, transporter EP550_18220 ENOG4105EZR dyp-type peroxidase family protein EP550_18225 ENOG4107R1I NAD-dependent malic enzyme EP550_18250 ENOG4105EUB pirin domain protein EP550_18285 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EP550_18290 ENOG4106MP8 UPF0754 membrane protein EP550_18295 ENOG4108VBZ doxx family EP550_18300 ENOG4105DQR SNARE associated Golgi EP550_18315 ENOG4107QJE Chromosome Partitioning Protein EP550_18325 ENOG4107PSF BolA-like protein EP550_18365 ENOG4105C1G acyl-Coa dehydrogenase EP550_18390 ENOG4105CSH Transporter EP550_18395 ENOG4105E39 Enoyl-CoA hydratase EP550_18400 ENOG4105E39 Enoyl-CoA hydratase EP550_18405 ENOG4105C1G acyl-Coa dehydrogenase EP550_18415 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EP550_18420 ENOG4105C26 Dehydrogenase EP550_18430 ENOG4105C85 amino acid EP550_18435 ENOG4105C85 amino acid EP550_18440 ENOG4105M4H endoribonuclease L-psp EP550_18455 ENOG4105EW9 transcriptional regulator AsnC family EP550_18480 ENOG4105D3G Pseudouridine synthase EP550_18530 ENOG4108I0Z Aconitate hydratase EP550_18535 ENOG4105BZN citrate synthase EP550_18540 ENOG4105CR4 methylisocitrate lyase EP550_18545 ENOG4105DRR Transcriptional regulator, GntR family EP550_18555 ENOG4105CGF Aromatic amino acid aminotransferase EP550_18560 ENOG4105CXG d-lactate dehydrogenase EP550_18570 ENOG41073TP transcriptional regulator EP550_18575 ENOG4105DAA L-lactate EP550_18580 ENOG4107QKV phosphomannomutase EP550_18590 ENOG4105CMR udp-glucose 4-epimerase EP550_18600 ENOG4105C6Y Udp-glucose 6-dehydrogenase EP550_18605 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EP550_18610 ENOG4105D3Q Sugar transferase EP550_18615 ENOG4108RYC glycosyltransferase EP550_18620 ENOG4105CG5 Glycosyl transferase (Group 1 EP550_18635 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) EP550_18650 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EP550_18655 ENOG4105J5G Transferase hexapeptide repeat containing protein EP550_18660 ENOG4107R5Z Oxidoreductase domain protein EP550_18665 ENOG4107QQG Dehydrogenase EP550_18670 ENOG4105DAY polysaccharide export protein EP550_18680 ENOG4105D75 Capsular exopolysaccharide family EP550_18685 ENOG4108V1T peptidylprolyl cis-trans isomerase EP550_18690 ENOG4108V1T peptidylprolyl cis-trans isomerase EP550_18695 ENOG4105CJR Integral membrane protein (MviN EP550_18700 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EP550_18705 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EP550_18715 ENOG4105HSS phospholipase C EP550_18740 ENOG41062JF Transcriptional regulator EP550_18755 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EP550_18760 ENOG4105UBK short-chain dehydrogenase reductase EP550_18775 ENOG4107QZM n-acetylglutamate synthase EP550_18780 ENOG4105GVF (ABC) transporter EP550_18785 ENOG4105GVF (ABC) transporter EP550_18790 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EP550_18795 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EP550_18800 ENOG4108VM9 ABC, transporter EP550_18805 ENOG4108R86 Transcriptional regulator EP550_18810 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) EP550_18820 ENOG4105DTN riboflavin biosynthesis protein ribF EP550_18825 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) EP550_18835 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase EP550_18875 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EP550_18930 ENOG4105CVE Lytic murein transglycosylase EP550_18935 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EP550_18940 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EP550_18955 ENOG4105DFU Cell wall formation (By similarity) EP550_18965 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EP550_18970 ENOG4105DU1 integral membrane protein, terc EP550_18980 ENOG4106032 Glutathionylspermidine synthase EP550_18990 ENOG4107QUY Guanine deaminase EP550_18995 ENOG4108UGV hypoxanthine phosphoribosyltransferase EP550_19010 ENOG4105T95 Thiol disulfide interChange protein EP550_19015 ENOG4105PGM cation diffusion facilitator family transporter EP550_19030 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EP550_19045 ENOG4105VG0 50S ribosomal protein l34 EP550_19075 ENOG4105UGU tonB-dependent Receptor EP550_19085 ENOG4105F9F transposase EP550_19095 ENOG4105F9F transposase