locus-tag	class	description
BL01_00190	COG2026	Addiction module toxin, RelE StbE family
BL01_00230	COG0592	DNA-directed DNA polymerase activity
BL01_00325	COG0582	viral genome integration into host DNA
BL01_00415	COG0084	hydrolase, TatD family'
BL01_00425	COG1585	Membrane protein implicated in regulation of membrane protease activity
BL01_00435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BL01_00440	COG4774	siderophore transport
BL01_00455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BL01_00460	COG0569	domain protein
BL01_00465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BL01_00495	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BL01_00500	COG0542	response to heat
BL01_00510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BL01_00525	COG1902	pentaerythritol trinitrate reductase activity
BL01_00525	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL01_00570	COG2323	membrane
BL01_00575	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BL01_00585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BL01_00590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BL01_00595	COG0183	Belongs to the thiolase family
BL01_00600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BL01_00605	COG0596	Alpha beta hydrolase
BL01_00610	COG2271	Major facilitator Superfamily
BL01_00615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BL01_00620	COG3485	protocatechuate 3,4-dioxygenase
BL01_00625	COG3485	protocatechuate 3,4-dioxygenase
BL01_00630	COG0710	3-dehydroquinate dehydratase activity
BL01_00635	COG3420	alginic acid biosynthetic process
BL01_00640	COG3659	wide pore channel activity
BL01_00645	COG4993	Dehydrogenase
BL01_00655	COG2391	methyltransferase activity
BL01_00670	COG1414	Transcriptional regulator
BL01_00675	COG0583	DNA-binding transcription factor activity
BL01_00680	COG1960	acyl-CoA dehydrogenase activity
BL01_00705	COG2814	Major facilitator Superfamily
BL01_00720	COG0154	amidase activity
BL01_00740	COG4638	Rieske (2fe-2S)
BL01_00750	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_00760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BL01_00770	COG3733	amine oxidase
BL01_00780	COG1012	belongs to the aldehyde dehydrogenase family
BL01_00790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BL01_00795	COG0183	Belongs to the thiolase family
BL01_00800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BL01_00805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BL01_00815	COG4829	muconolactone delta-isomerase
BL01_00820	COG4948	Mandelate Racemase Muconate Lactonizing
BL01_00825	COG0583	DNA-binding transcription factor activity
BL01_00835	COG2186	Transcriptional regulator
BL01_00860	COG1309	transcriptional regulator
BL01_00895	COG0758	DNA mediated transformation
BL01_00905	COG0697	spore germination
BL01_00910	COG1309	transcriptional regulator
BL01_00925	COG0386	Belongs to the glutathione peroxidase family
BL01_00990	COG1121	(ABC) transporter
BL01_00995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BL01_01000	COG1280	lysine exporter protein (LysE YggA)
BL01_01005	COG2837	iron assimilation
BL01_01015	COG0281	malic enzyme
BL01_01060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BL01_01060	COG0519	Catalyzes the synthesis of GMP from XMP
BL01_01065	COG4399	Belongs to the UPF0754 family
BL01_01070	COG2259	Doxx family
BL01_01075	COG0586	Pfam SNARE associated Golgi protein
BL01_01090	COG1192	Involved in chromosome partitioning
BL01_01100	COG0271	Belongs to the BolA IbaG family
BL01_01120	COG2267	carboxylic ester hydrolase activity
BL01_01135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BL01_01145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BL01_01145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BL01_01145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BL01_01145	COG3321	synthase
BL01_01150	COG1960	acyl-CoA dehydrogenase activity
BL01_01160	COG2197	response regulator
BL01_01170	COG3916	Acyl-homoserine-lactone synthase
BL01_01175	COG0477	Major facilitator Superfamily
BL01_01180	COG1024	Enoyl-CoA hydratase
BL01_01185	COG1024	Enoyl-CoA hydratase
BL01_01190	COG1960	acyl-CoA dehydrogenase activity
BL01_01195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BL01_01215	COG1113	amino acid transport
BL01_01220	COG1113	amino acid transport
BL01_01225	COG0251	oxidation-reduction process
BL01_01240	COG1522	sequence-specific DNA binding
BL01_01265	COG0564	pseudouridine synthase activity
BL01_01325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BL01_01340	COG1802	Transcriptional regulator
BL01_01345	COG1448	Aminotransferase
BL01_01350	COG0277	FAD linked oxidase domain protein
BL01_01360	COG2186	Transcriptional regulator
BL01_01370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BL01_01375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BL01_01390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BL01_01395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BL01_01450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BL01_01480	COG0728	peptidoglycan biosynthetic process
BL01_01485	COG3023	N-Acetylmuramoyl-L-alanine amidase
BL01_01545	COG0546	phosphoglycolate phosphatase activity
BL01_01550	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_01570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BL01_01575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BL01_01580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BL01_01585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BL01_01590	COG1116	anion transmembrane transporter activity
BL01_01595	COG1309	transcriptional regulator
BL01_01600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BL01_01610	COG0196	riboflavin kinase activity
BL01_01615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BL01_01625	COG1047	Peptidyl-prolyl cis-trans
BL01_01675	COG1280	lysine exporter protein (LysE YggA)
BL01_01680	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BL01_01680	COG1674	ftsk spoiiie
BL01_01685	COG0492	ferredoxin-NADP+ reductase activity
BL01_01690	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BL01_01700	COG0456	acetyltransferase
BL01_01735	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BL01_01745	COG0753	catalase activity
BL01_01765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BL01_01825	COG3433	isochorismatase activity
BL01_01825	COG1535	isochorismatase
BL01_01830	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_01835	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BL01_01840	COG4149	molybdate abc transporter
BL01_01845	COG0725	ABC transporter, periplasmic molybdate-binding protein
BL01_01855	COG4638	Rieske (2fe-2S)
BL01_01860	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BL01_01865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BL01_01865	COG0543	2 iron, 2 sulfur cluster binding
BL01_01880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BL01_01890	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_01895	COG0412	Dienelactone hydrolase
BL01_01905	COG2207	Transcriptional regulator
BL01_01930	COG0753	catalase activity
BL01_01935	COG3038	cytochrome b561
BL01_01955	COG2267	carboxylic ester hydrolase activity
BL01_01960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BL01_01965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BL01_01970	COG1012	belongs to the aldehyde dehydrogenase family
BL01_01980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BL01_01990	COG1012	belongs to the aldehyde dehydrogenase family
BL01_01995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BL01_02000	COG0583	DNA-binding transcription factor activity
BL01_02010	COG1414	Transcriptional regulator
BL01_02015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BL01_02025	COG1840	ABC-type Fe3 transport system, periplasmic component
BL01_02030	COG3842	ATPase activity
BL01_02045	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BL01_02050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BL01_02055	COG2814	Major facilitator Superfamily
BL01_02060	COG1960	acyl-CoA dehydrogenase activity
BL01_02080	COG1024	Enoyl-CoA hydratase
BL01_02090	COG2814	Major facilitator Superfamily
BL01_02100	COG0183	Belongs to the thiolase family
BL01_02105	COG1250	3-hydroxyacyl-CoA dehydrogenase
BL01_02110	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_02115	COG1024	Enoyl-CoA hydratase
BL01_02120	COG1960	acyl-CoA dehydrogenase activity
BL01_02125	COG2814	Major facilitator Superfamily
BL01_02130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BL01_02135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BL01_02145	COG2814	Major facilitator Superfamily
BL01_02155	COG1960	acyl-CoA dehydrogenase activity
BL01_02170	COG0583	DNA-binding transcription factor activity
BL01_02185	COG1024	Enoyl-CoA hydratase
BL01_02190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BL01_02195	COG1960	acyl-CoA dehydrogenase activity
BL01_02200	COG1309	transcriptional regulator
BL01_02205	COG0318	PFAM AMP-dependent synthetase and ligase
BL01_02225	COG0583	DNA-binding transcription factor activity
BL01_02275	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_02295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BL01_02315	COG0784	Response regulator, receiver
BL01_02315	COG2205	protein histidine kinase activity
BL01_02330	COG0765	amino acid transport
BL01_02335	COG0765	amino acid transport
BL01_02340	COG1126	abc transporter atp-binding protein
BL01_02345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BL01_02350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BL01_02360	COG1280	lysine exporter protein (LysE YggA)
BL01_02365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BL01_02370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BL01_02375	COG1045	serine acetyltransferase
BL01_02395	COG0583	DNA-binding transcription factor activity
BL01_02400	COG0625	glutathione transferase activity
BL01_02405	COG0625	glutathione transferase activity
BL01_02410	COG0583	DNA-binding transcription factor activity
BL01_02420	COG1346	cytolysis
BL01_02440	COG2814	Major facilitator Superfamily
BL01_02455	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BL01_02460	COG3052	prosthetic group binding
BL01_02480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BL01_02500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BL01_02510	COG1294	oxidase, subunit
BL01_02515	COG1271	oxidase subunit
BL01_02535	COG0477	Major facilitator Superfamily
BL01_02545	COG4521	taurine ABC transporter
BL01_02550	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BL01_02555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BL01_02560	COG2175	clavaminate synthase activity
BL01_02570	COG1953	Uracil, thiamine, allantoin
BL01_02580	COG0583	DNA-binding transcription factor activity
BL01_02590	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BL01_02605	COG0640	Transcriptional regulator
BL01_02610	COG0798	PFAM Bile acid sodium symporter
BL01_02615	COG0583	DNA-binding transcription factor activity
BL01_02630	COG3634	alkyl hydroperoxide reductase activity
BL01_02670	COG0436	Aminotransferase
BL01_02680	COG0386	Belongs to the glutathione peroxidase family
BL01_02720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BL01_02745	COG0012	GTP binding
BL01_02750	COG2011	ABC-type metal ion transport system permease component
BL01_02755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BL01_02765	COG1464	Belongs to the NlpA lipoprotein family
BL01_02785	COG0583	DNA-binding transcription factor activity
BL01_02795	COG0625	glutathione transferase activity
BL01_02800	COG2378	regulation of single-species biofilm formation
BL01_02805	COG0546	phosphoglycolate phosphatase activity
BL01_02815	COG1530	ribonuclease E activity
BL01_02835	COG0583	DNA-binding transcription factor activity
BL01_02840	COG4221	oxidoreductase activity
BL01_02845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BL01_02855	COG0534	Mate efflux family protein
BL01_02870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BL01_02905	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BL01_02910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BL01_02925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BL01_02935	COG0644	oxidoreductase
BL01_02935	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BL01_02940	COG0425	Belongs to the sulfur carrier protein TusA family
BL01_02945	COG4535	Mg2 and Co2 transporter CorC
BL01_02955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BL01_02975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BL01_02980	COG0475	glutathione-regulated potassium exporter activity
BL01_02980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BL01_02985	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BL01_02995	COG0484	heat shock protein binding
BL01_03000	COG0789	Transcriptional regulator
BL01_03005	COG0598	Magnesium transport protein CorA
BL01_03025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BL01_03030	COG1074	ATP-dependent DNA helicase activity
BL01_03035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BL01_03055	COG2226	methyltransferase
BL01_03070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BL01_03075	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BL01_03090	COG2111	Na H antiporter
BL01_03090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BL01_03095	COG1006	Multisubunit Na H antiporter MnhC subunit
BL01_03100	COG0651	ATP synthesis coupled electron transport
BL01_03110	COG2212	antiporter activity
BL01_03130	COG0195	Participates in both transcription termination and antitermination
BL01_03180	COG0237	dephospho-CoA kinase activity
BL01_03190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BL01_03205	COG0497	DNA recombination
BL01_03215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BL01_03245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BL01_03245	COG2169	Transcriptional regulator
BL01_03250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BL01_03320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BL01_03335	COG0326	Molecular chaperone. Has ATPase activity
BL01_03350	COG2056	Na+-H+ antiporter family
BL01_03355	COG0596	Alpha beta hydrolase
BL01_03435	COG0824	Thioesterase
BL01_03440	COG1454	alcohol dehydrogenase
BL01_03450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BL01_03470	COG0069	glutamate synthase activity
BL01_03575	COG0557	exoribonuclease II activity
BL01_03580	COG0339	signal peptide processing
BL01_03585	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BL01_03625	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BL01_03630	COG1960	acyl-CoA dehydrogenase activity
BL01_03655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BL01_03665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BL01_03785	COG0626	cystathionine gamma-synthase activity
BL01_03790	COG0433	COG0433 Predicted ATPase
BL01_03795	COG1017	nitric oxide dioxygenase activity
BL01_03795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BL01_03800	COG1959	2 iron, 2 sulfur cluster binding
BL01_03815	COG1301	dicarboxylic acid transport
BL01_03820	COG1946	Acyl-CoA thioesterase
BL01_03840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BL01_03845	COG1040	competence protein
BL01_03850	COG0494	nUDIX hydrolase
BL01_03860	COG0598	Magnesium transport protein CorA
BL01_03870	COG2854	intermembrane phospholipid transfer
BL01_03880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BL01_03885	COG1127	ABC transporter
BL01_03895	COG0513	Belongs to the DEAD box helicase family
BL01_03915	COG0408	coproporphyrinogen oxidase activity
BL01_03930	COG1960	acyl-CoA dehydrogenase activity
BL01_03940	COG1983	PspC domain protein
BL01_03945	COG0517	IMP dehydrogenase activity
BL01_03990	COG0583	DNA-binding transcription factor activity
BL01_04030	COG1012	belongs to the aldehyde dehydrogenase family
BL01_04040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BL01_04045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BL01_04060	COG1294	oxidase, subunit
BL01_04080	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BL01_04090	COG0552	protein localization to endoplasmic reticulum
BL01_04120	COG0516	GMP reductase activity
BL01_04120	COG0517	IMP dehydrogenase activity
BL01_04125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BL01_04130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BL01_04140	COG0583	DNA-binding transcription factor activity
BL01_04145	COG0024	Methionine aminopeptidase
BL01_04175	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL01_04175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BL01_04180	COG1105	Belongs to the carbohydrate kinase PfkB family
BL01_04185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL01_04185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BL01_04185	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BL01_04210	COG3300	MHYT domain
BL01_04210	COG5001	Diguanylate cyclase
BL01_04225	COG2135	peptidase activity
BL01_04230	COG0659	secondary active sulfate transmembrane transporter activity
BL01_04245	COG1113	amino acid transport
BL01_04255	COG1522	sequence-specific DNA binding
BL01_04280	COG1011	Hydrolase
BL01_04285	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BL01_04295	COG2137	regulation of response to DNA damage stimulus
BL01_04305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BL01_04340	COG0575	Belongs to the CDS family
BL01_04345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BL01_04365	COG3852	Histidine kinase
BL01_04370	COG2204	response regulator
BL01_04425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BL01_04430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BL01_04450	COG0697	spore germination
BL01_04455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BL01_04465	COG0303	'Molybdopterin
BL01_04470	COG0315	cyclic pyranopterin monophosphate synthase activity
BL01_04470	COG0521	Mo-molybdopterin cofactor biosynthetic process
BL01_04485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BL01_04490	COG0243	molybdopterin cofactor binding
BL01_04500	COG0243	molybdopterin cofactor binding
BL01_04505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BL01_04510	COG2146	nitrite reductase [NAD(P)H] activity
BL01_04510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BL01_04520	COG0745	RESPONSE REGULATOR receiver
BL01_04525	COG1116	anion transmembrane transporter activity
BL01_04525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BL01_04540	COG0511	ligase activity, forming carbon-carbon bonds
BL01_04555	COG2814	Major facilitator Superfamily
BL01_04595	COG0765	amino acid transport
BL01_04600	COG0765	amino acid transport
BL01_04605	COG1126	abc transporter atp-binding protein
BL01_04615	COG1522	sequence-specific DNA binding
BL01_04650	COG3739	integral membrane protein
BL01_04665	COG1169	isochorismate synthase
BL01_04675	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BL01_04685	COG1132	(ABC) transporter
BL01_04700	COG3433	isochorismatase activity
BL01_04700	COG1535	isochorismatase
BL01_04705	COG1021	2,3-dihydroxybenzoate-AMP ligase
BL01_04710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BL01_04720	COG4774	siderophore transport
BL01_04725	COG4607	ABC-type enterochelin transport system periplasmic component
BL01_04730	COG4604	ABC transporter, ATP-binding protein
BL01_04735	COG4605	iron ion homeostasis
BL01_04740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BL01_04745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BL01_04760	COG2964	Protein conserved in bacteria
BL01_04770	COG1741	Belongs to the pirin family
BL01_04795	COG1309	transcriptional regulator
BL01_04805	COG4948	Mandelate Racemase Muconate Lactonizing
BL01_04810	COG2814	Major facilitator Superfamily
BL01_04845	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BL01_04845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BL01_04850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BL01_04865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BL01_04870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BL01_04875	COG0583	DNA-binding transcription factor activity
BL01_04880	COG1113	amino acid transport
BL01_04900	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BL01_04900	COG2508	Transcriptional regulator
BL01_04935	COG2879	small protein
BL01_04940	COG1966	Carbon starvation protein
BL01_04985	COG1067	ATP-dependent peptidase activity
BL01_04990	COG0583	DNA-binding transcription factor activity
BL01_05015	COG1686	Belongs to the peptidase S11 family
BL01_05020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BL01_05055	COG2321	neutral zinc metallopeptidase
BL01_05060	COG2354	Protein conserved in bacteria
BL01_05080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BL01_05095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BL01_05100	COG1053	succinate dehydrogenase
BL01_05105	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BL01_05110	COG2009	succinate dehydrogenase
BL01_05155	COG2921	Belongs to the UPF0250 family
BL01_05160	COG0321	lipoyl(octanoyl) transferase activity
BL01_05175	COG0531	amino acid
BL01_05185	COG1733	regulation of RNA biosynthetic process
BL01_05190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BL01_05195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BL01_05195	COG1648	precorrin-2 dehydrogenase activity
BL01_05210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BL01_05240	COG0671	phosphoesterase, PA-phosphatase related
BL01_05245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BL01_05255	COG1538	Outer membrane efflux protein
BL01_05260	COG0393	Putative heavy-metal-binding
BL01_05265	COG0393	Putative heavy-metal-binding
BL01_05275	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_05285	COG0525	valine-tRNA ligase activity
BL01_05305	COG0583	DNA-binding transcription factor activity
BL01_05310	COG0004	ammonium transporteR
BL01_05320	COG0642	Histidine kinase
BL01_05325	COG0745	RESPONSE REGULATOR receiver
BL01_05330	COG2194	sulfuric ester hydrolase activity
BL01_05355	COG1752	Esterase of the alpha-beta hydrolase superfamily
BL01_05370	COG2315	Protein conserved in bacteria
BL01_05375	COG0142	geranyltranstransferase activity
BL01_05380	COG2828	Protein conserved in bacteria
BL01_05385	COG1113	amino acid transport
BL01_05405	COG2207	Transcriptional regulator
BL01_05435	COG2249	NAD(P)H dehydrogenase (quinone) activity
BL01_05455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BL01_05465	COG1530	ribonuclease E activity
BL01_05470	COG0424	maF-like protein
BL01_05475	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BL01_05480	COG1792	Involved in formation and maintenance of cell shape
BL01_05485	COG1077	Cell shape determining protein MreB Mrl
BL01_05490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BL01_05500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BL01_05515	COG2843	Capsule synthesis protein
BL01_05530	COG0589	response to stress
BL01_05550	COG0505	Belongs to the CarA family
BL01_05575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BL01_05580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BL01_05630	COG0477	Major facilitator Superfamily
BL01_05635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BL01_05655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BL01_05685	COG0584	glycerophosphoryl diester phosphodiesterase
BL01_05705	COG0741	lytic transglycosylase activity
BL01_05725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BL01_05740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BL01_05765	COG0778	Nitroreductase
BL01_05780	COG1929	Belongs to the glycerate kinase type-1 family
BL01_05785	COG0243	molybdopterin cofactor binding
BL01_05790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BL01_05795	COG3339	Conserved Protein
BL01_05805	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BL01_05820	COG1113	amino acid transport
BL01_05830	COG0019	diaminopimelate decarboxylase activity
BL01_05840	COG1280	lysine exporter protein (LysE YggA)
BL01_05845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BL01_05875	COG0463	Glycosyl transferase, family 2
BL01_05895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BL01_05925	COG4591	ABC-type transport system involved in lipoprotein release permease component
BL01_05930	COG1136	(ABC) transporter
BL01_05935	COG0658	competence protein
BL01_05935	COG2333	competence protein COMEC
BL01_05945	COG0616	signal peptide processing
BL01_05945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BL01_05950	COG0596	Alpha beta hydrolase
BL01_05955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BL01_05965	COG0628	permease
BL01_06000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BL01_06020	COG0823	Involved in the tonB-independent uptake of proteins
BL01_06040	COG0824	Thioesterase
BL01_06045	COG1473	amidohydrolase
BL01_06065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BL01_06065	COG0047	phosphoribosylformylglycinamidine synthase activity
BL01_06070	COG2814	Major facilitator Superfamily
BL01_06080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BL01_06085	COG1024	Enoyl-CoA hydratase
BL01_06090	COG1056	cytidyltransferase-related domain
BL01_06090	COG1051	belongs to the nudix hydrolase family
BL01_06100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BL01_06115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BL01_06130	COG4625	pathogenesis
BL01_06135	COG0583	DNA-binding transcription factor activity
BL01_06140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BL01_06145	COG4208	sulfate ABC transporter
BL01_06150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BL01_06160	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BL01_06165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BL01_06170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BL01_06190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BL01_06205	COG0681	Belongs to the peptidase S26 family
BL01_06220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BL01_06230	COG1381	Involved in DNA repair and RecF pathway recombination
BL01_06235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BL01_06245	COG4221	oxidoreductase activity
BL01_06290	COG0556	nucleotide-excision repair
BL01_06345	COG2070	2-Nitropropane dioxygenase
BL01_06375	COG1215	transferase activity, transferring glycosyl groups
BL01_06390	COG0415	Belongs to the DNA photolyase family
BL01_06400	COG1252	NADH dehydrogenase
BL01_06405	COG1686	Belongs to the peptidase S11 family
BL01_06420	COG1187	pseudouridine synthase activity
BL01_06440	COG0477	Major facilitator Superfamily
BL01_06445	COG0583	DNA-binding transcription factor activity
BL01_06460	COG0612	Peptidase, M16
BL01_06485	COG0352	thiamine-phosphate diphosphorylase activity
BL01_06520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BL01_06535	COG1309	transcriptional regulator
BL01_06545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BL01_06550	COG0076	glutamate decarboxylase activity
BL01_06560	COG1522	sequence-specific DNA binding
BL01_06565	COG3961	Belongs to the TPP enzyme family
BL01_06570	COG1113	amino acid transport
BL01_06575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BL01_06580	COG0573	inorganic phosphate transmembrane transporter activity
BL01_06590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BL01_06595	COG0616	signal peptide processing
BL01_06620	COG0733	neurotransmitter:sodium symporter activity
BL01_06660	COG2233	PERMEase
BL01_06675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BL01_06710	COG2814	Major facilitator Superfamily
BL01_06715	COG0656	L-ascorbic acid biosynthetic process
BL01_06720	COG0583	DNA-binding transcription factor activity
BL01_06730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BL01_06735	COG1064	alcohol dehydrogenase
BL01_06740	COG2818	Glycosylase
BL01_06755	COG1194	a g-specific adenine glycosylase
BL01_06775	COG2983	Belongs to the UPF0260 family
BL01_06780	COG2133	pyrroloquinoline quinone binding
BL01_06785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BL01_06790	COG2116	formate transmembrane transporter activity
BL01_06815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BL01_06820	COG1335	isochorismatase
BL01_06825	COG0385	Bile acid
BL01_06830	COG0534	Mate efflux family protein
BL01_06835	COG1683	Conserved Protein
BL01_06855	COG0625	glutathione transferase activity
BL01_06865	COG1113	amino acid transport
BL01_06875	COG0523	cobalamin synthesis protein
BL01_06885	COG2188	Transcriptional regulator
BL01_06915	COG0010	Belongs to the arginase family
BL01_06930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BL01_06935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BL01_06945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BL01_06950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BL01_07050	COG0534	Mate efflux family protein
BL01_07055	COG0436	Aminotransferase
BL01_07060	COG2733	membrane
BL01_07075	COG2918	glutathione biosynthetic process
BL01_07085	COG3501	Rhs element vgr protein
BL01_07090	COG1388	LysM domain
BL01_07090	COG0791	NLP P60 protein
BL01_07105	COG3150	esterase
BL01_07120	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_07125	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BL01_07135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BL01_07145	COG2233	PERMEase
BL01_07150	COG2351	hydroxyisourate hydrolase activity
BL01_07185	COG3706	GGDEF domain
BL01_07200	COG1393	Belongs to the ArsC family
BL01_07205	COG0708	Exodeoxyribonuclease III
BL01_07225	COG0189	ligase activity
BL01_07245	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BL01_07255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BL01_07270	COG4942	peptidase
BL01_07280	COG0508	dehydrogenase complex catalyzes the overall conversion of
BL01_07290	COG2119	membrane
BL01_07295	COG4774	siderophore transport
BL01_07300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BL01_07300	COG0426	domain, Protein
BL01_07325	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BL01_07345	COG1902	pentaerythritol trinitrate reductase activity
BL01_07350	COG1519	Transferase
BL01_07355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BL01_07360	COG0668	transmembrane transport
BL01_07370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BL01_07375	COG1335	isochorismatase
BL01_07380	COG1522	sequence-specific DNA binding
BL01_07405	COG2205	protein histidine kinase activity
BL01_07415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BL01_07435	COG0745	RESPONSE REGULATOR receiver
BL01_07440	COG2205	protein histidine kinase activity
BL01_07475	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BL01_07505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BL01_07510	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BL01_07530	COG0583	DNA-binding transcription factor activity
BL01_07550	COG0668	transmembrane transport
BL01_07560	COG2081	HI0933 family
BL01_07565	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BL01_07595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BL01_07595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BL01_07605	COG0489	protein tyrosine kinase activity
BL01_07655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BL01_07665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BL01_07680	COG0730	response to heat
BL01_07690	COG1196	nuclear chromosome segregation
BL01_07710	COG2223	nitrite transmembrane transporter activity
BL01_07715	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BL01_07720	COG1877	trehalose-phosphatase activity
BL01_07725	COG2226	methyltransferase
BL01_07725	COG0596	Alpha beta hydrolase
BL01_07725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BL01_07740	COG4106	trans-aconitate 2-methyltransferase activity
BL01_07755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BL01_07760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BL01_07765	COG0009	L-threonylcarbamoyladenylate synthase
BL01_07770	COG3101	peptidyl-lysine hydroxylation
BL01_07775	COG1399	metal-binding, possibly nucleic acid-binding protein
BL01_07800	COG1652	LysM domain
BL01_07805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BL01_07805	COG0352	thiamine-phosphate diphosphorylase activity
BL01_07805	COG0351	phosphomethylpyrimidine kinase
BL01_07815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BL01_07845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BL01_07875	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BL01_07890	COG0358	DNA primase activity
BL01_07900	COG0564	pseudouridine synthase activity
BL01_07925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BL01_07940	COG0583	DNA-binding transcription factor activity
BL01_07945	COG0473	3-isopropylmalate dehydrogenase activity
BL01_07965	COG1012	belongs to the aldehyde dehydrogenase family
BL01_07985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BL01_07985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BL01_08035	COG0583	DNA-binding transcription factor activity
BL01_08045	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BL01_08050	COG2031	fatty acid transporter
BL01_08055	COG0183	Belongs to the thiolase family
BL01_08060	COG0583	DNA-binding transcription factor activity
BL01_08065	COG0583	DNA-binding transcription factor activity
BL01_08080	COG1027	Aspartate ammonia-lyase
BL01_08090	COG0477	Major facilitator Superfamily
BL01_08110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BL01_08115	COG4521	taurine ABC transporter
BL01_08140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BL01_08145	COG1733	regulation of RNA biosynthetic process
BL01_08150	COG3708	Transcriptional regulator
BL01_08150	COG2207	Transcriptional regulator
BL01_08165	COG0730	response to heat
BL01_08175	COG3453	Protein conserved in bacteria
BL01_08175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BL01_08185	COG3781	membrane
BL01_08190	COG1063	alcohol dehydrogenase
BL01_08200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BL01_08205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BL01_08210	COG0022	dehydrogenase e1 component
BL01_08215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BL01_08220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BL01_08235	COG3706	GGDEF domain
BL01_08250	COG0133	tryptophan synthase activity
BL01_08260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BL01_08295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BL01_08320	COG2226	methyltransferase
BL01_08375	COG0842	Transport permease protein
BL01_08380	COG0842	Transport permease protein
BL01_08385	COG1131	(ABC) transporter
BL01_08400	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BL01_08405	COG4773	Receptor
BL01_08425	COG0730	response to heat
BL01_08430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BL01_08450	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BL01_08470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BL01_08510	COG4264	IucA IucC family
BL01_08515	COG4264	IucA IucC family
BL01_08535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BL01_08550	COG1960	acyl-CoA dehydrogenase activity
BL01_08555	COG1960	acyl-CoA dehydrogenase activity
BL01_08560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BL01_08565	COG2207	Transcriptional regulator
BL01_08570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BL01_08575	COG0776	regulation of translation
BL01_08600	COG0822	iron-sulfur transferase activity
BL01_08605	COG0316	Belongs to the HesB IscA family
BL01_08635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BL01_08655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BL01_08660	COG0702	epimerase
BL01_08695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BL01_08705	COG0339	signal peptide processing
BL01_08730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BL01_08760	COG0308	aminopeptidase N
BL01_08765	COG0512	Glutamine amidotransferase of anthranilate synthase
BL01_08775	COG3104	oligopeptide transport
BL01_08790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BL01_08825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BL01_08830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BL01_08835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BL01_08855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BL01_08860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BL01_08865	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BL01_08880	COG1960	acyl-CoA dehydrogenase activity
BL01_08885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BL01_08890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BL01_08905	COG2223	nitrite transmembrane transporter activity
BL01_08915	COG0024	Methionine aminopeptidase
BL01_08920	COG0052	Belongs to the universal ribosomal protein uS2 family
BL01_08935	COG2207	Transcriptional regulator
BL01_08960	COG2951	lytic endotransglycosylase activity
BL01_08965	COG0772	Belongs to the SEDS family
BL01_08980	COG0842	Transport permease protein
BL01_08985	COG1131	(ABC) transporter
BL01_09020	COG1538	Outer membrane efflux protein
BL01_09030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BL01_09050	COG4215	(ABC) transporter
BL01_09055	COG4160	amino acid transport
BL01_09060	COG4598	ABC transporter
BL01_09070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BL01_09080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BL01_09095	COG1720	tRNA m6t6A37 methyltransferase activity
BL01_09115	COG0745	RESPONSE REGULATOR receiver
BL01_09120	COG0642	Histidine kinase
BL01_09130	COG0494	nUDIX hydrolase
BL01_09140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BL01_09145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BL01_09150	COG3139	Protein of unknown function (DUF1315)
BL01_09155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BL01_09160	COG1301	dicarboxylic acid transport
BL01_09165	COG1960	acyl-CoA dehydrogenase activity
BL01_09170	COG2819	hydrolase of the alpha beta superfamily
BL01_09180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BL01_09190	COG2195	Cleaves the N-terminal amino acid of tripeptides
BL01_09195	COG1234	tRNA 3'-trailer cleavage
BL01_09225	COG2363	Small membrane protein
BL01_09245	COG0513	Belongs to the DEAD box helicase family
BL01_09255	COG0778	Nitroreductase
BL01_09285	COG1286	toxin biosynthetic process
BL01_09310	COG4783	chaperone-mediated protein folding
BL01_09315	COG1610	YqeY-like protein
BL01_09320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BL01_09415	COG3111	PFAM Bacterial OB fold (BOF) protein
BL01_09440	COG3243	poly(R)-hydroxyalkanoic acid synthase
BL01_09445	COG0786	glutamate:sodium symporter activity
BL01_09455	COG2186	Transcriptional regulator
BL01_09480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BL01_09600	COG2198	Histidine kinase
BL01_09600	COG0784	Response regulator, receiver
BL01_09600	COG2205	protein histidine kinase activity
BL01_09605	COG3162	membrane
BL01_09610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BL01_09620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BL01_09630	COG3706	GGDEF domain
BL01_09640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BL01_09645	COG1309	transcriptional regulator
BL01_09665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BL01_09665	COG0352	thiamine-phosphate diphosphorylase activity
BL01_09665	COG0351	phosphomethylpyrimidine kinase
BL01_09675	COG2814	Major facilitator Superfamily
BL01_09690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BL01_09700	COG1113	amino acid transport
BL01_09710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BL01_09715	COG1012	belongs to the aldehyde dehydrogenase family
BL01_09725	COG1335	isochorismatase
BL01_09755	COG2814	Major facilitator Superfamily
BL01_09760	COG0583	DNA-binding transcription factor activity
BL01_09780	COG0667	Aldo Keto reductase
BL01_09820	COG1733	regulation of RNA biosynthetic process
BL01_09825	COG2249	NAD(P)H dehydrogenase (quinone) activity
BL01_09890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BL01_09905	COG2329	Antibiotic biosynthesis monooxygenase
BL01_09935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BL01_09965	COG0427	acetyl-CoA hydrolase
BL01_09975	COG0745	RESPONSE REGULATOR receiver
BL01_09985	COG0659	secondary active sulfate transmembrane transporter activity
BL01_09990	COG4221	oxidoreductase activity
BL01_10000	COG0488	(ABC) transporter
BL01_10090	COG0833	amino acid
BL01_10140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BL01_10145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BL01_10160	COG2226	methyltransferase
BL01_10210	COG0070	glutamate synthase
BL01_10210	COG0069	glutamate synthase activity
BL01_10210	COG0067	glutamate synthase
BL01_10215	COG0493	'glutamate synthase
BL01_10225	COG1704	LemA family
BL01_10230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BL01_10250	COG3307	-O-antigen
BL01_10270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BL01_10280	COG0194	GDP metabolic process
BL01_10330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BL01_10350	COG5380	lipid catabolic process
BL01_10355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BL01_10380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BL01_10385	COG0277	FAD linked oxidase domain protein
BL01_10395	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BL01_10400	COG2249	NAD(P)H dehydrogenase (quinone) activity
BL01_10415	COG1289	transmembrane transporter activity
BL01_10425	COG0628	permease
BL01_10430	COG1192	Involved in chromosome partitioning
BL01_10465	COG2094	Belongs to the DNA glycosylase MPG family
BL01_10495	COG2233	PERMEase
BL01_10505	COG0833	amino acid
BL01_10510	COG1690	Belongs to the RtcB family
BL01_10520	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BL01_10520	COG2885	chlorophyll binding
BL01_10530	COG0183	Belongs to the thiolase family
BL01_10550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BL01_10570	COG2207	Transcriptional regulator
BL01_10575	COG0183	Belongs to the thiolase family
BL01_10605	COG1272	protein, Hemolysin III
BL01_10610	COG0477	Major facilitator Superfamily
BL01_10625	COG0450	alkyl hydroperoxide reductase
BL01_10645	COG0285	dihydrofolate synthase activity
BL01_10680	COG0133	tryptophan synthase activity
BL01_10695	COG2096	Adenosyltransferase
BL01_10715	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BL01_10720	COG0745	RESPONSE REGULATOR receiver
BL01_10725	COG2205	protein histidine kinase activity
BL01_10735	COG1960	acyl-CoA dehydrogenase activity
BL01_10740	COG1960	acyl-CoA dehydrogenase activity
BL01_10745	COG0583	DNA-binding transcription factor activity
BL01_10750	COG0625	glutathione transferase activity
BL01_10815	COG0438	transferase activity, transferring glycosyl groups
BL01_10820	COG0463	Glycosyl transferase, family 2
BL01_10825	COG0726	polysaccharide deacetylase
BL01_10845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BL01_10850	COG2205	protein histidine kinase activity
BL01_10880	COG1862	Preprotein translocase
BL01_10890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BL01_10895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BL01_10905	COG3781	membrane
BL01_10910	COG0613	PHP domain protein
BL01_10920	COG2350	Protein conserved in bacteria
BL01_10950	COG1607	acyl-coa hydrolase
BL01_10965	COG3453	Protein conserved in bacteria
BL01_10965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BL01_11005	COG1214	PFAM Peptidase M22, glycoprotease
BL01_11030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BL01_11035	COG0561	phosphatase activity
BL01_11045	COG2132	Multicopper oxidase
BL01_11050	COG3667	copper resistance
BL01_11065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BL01_11070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BL01_11075	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BL01_11105	COG1063	alcohol dehydrogenase
BL01_11110	COG0583	DNA-binding transcription factor activity
BL01_11115	COG1960	acyl-CoA dehydrogenase activity
BL01_11120	COG2814	Major facilitator Superfamily
BL01_11125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BL01_11135	COG1053	succinate dehydrogenase
BL01_11140	COG0583	DNA-binding transcription factor activity
BL01_11155	COG0583	DNA-binding transcription factor activity
BL01_11165	COG1473	amidohydrolase
BL01_11185	COG0583	DNA-binding transcription factor activity
BL01_11195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BL01_11200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BL01_11230	COG0384	phenazine biosynthesis protein PhzF
BL01_11245	COG0477	Major facilitator Superfamily
BL01_11250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BL01_11260	COG1595	DNA-templated transcription, initiation
BL01_11315	COG0531	amino acid
BL01_11320	COG2040	homocysteine
BL01_11350	COG1309	transcriptional regulator
BL01_11355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BL01_11360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BL01_11370	COG1607	acyl-coa hydrolase
BL01_11380	COG0523	cobalamin synthesis protein
BL01_11390	COG4681	YaeQ
BL01_11400	COG0726	polysaccharide deacetylase
BL01_11400	COG1649	PFAM Uncharacterised BCR, COG1649
BL01_11405	COG1215	transferase activity, transferring glycosyl groups
BL01_11415	COG1024	Enoyl-CoA hydratase
BL01_11430	COG1414	Transcriptional regulator
BL01_11450	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_11460	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL01_11465	COG2271	Major facilitator Superfamily
BL01_11475	COG2267	carboxylic ester hydrolase activity
BL01_11480	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_11495	COG0028	Belongs to the TPP enzyme family
BL01_11505	COG0477	Major facilitator Superfamily
BL01_11515	COG0242	peptide deformylase activity
BL01_11520	COG2066	Belongs to the glutaminase family
BL01_11525	COG2207	Transcriptional regulator
BL01_11530	COG2223	nitrite transmembrane transporter activity
BL01_11545	COG0583	DNA-binding transcription factor activity
BL01_11550	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_11555	COG2271	Major facilitator Superfamily
BL01_11560	COG3959	Transketolase, thiamine diphosphate binding domain
BL01_11565	COG3958	Transketolase
BL01_11575	COG0306	phosphate transporter
BL01_11595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BL01_11640	COG4181	ATPase activity
BL01_11645	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BL01_11670	COG0583	DNA-binding transcription factor activity
BL01_11680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BL01_11685	COG1773	rubredoxin
BL01_11720	COG2894	cell division
BL01_11735	COG0204	Acyl-transferase
BL01_11740	COG2885	chlorophyll binding
BL01_11745	COG0210	DNA helicase
BL01_11755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BL01_11770	COG0121	glutamine amidotransferase
BL01_11790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BL01_11795	COG0735	belongs to the Fur family
BL01_11825	COG0420	3'-5' exonuclease activity
BL01_11845	COG1090	epimerase
BL01_11860	COG2050	protein possibly involved in aromatic compounds catabolism
BL01_11870	COG2814	Major facilitator Superfamily
BL01_11875	COG0405	Gamma-glutamyltransferase
BL01_11945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BL01_12040	COG1484	DNA-dependent DNA replication
BL01_12130	COG2194	sulfuric ester hydrolase activity
BL01_12215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BL01_12220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BL01_12250	COG0776	regulation of translation
BL01_12270	COG0590	tRNA wobble adenosine to inosine editing
BL01_12300	COG2165	general secretion pathway protein
BL01_12315	COG0084	hydrolase, TatD family'
BL01_12335	COG1663	tetraacyldisaccharide 4'-kinase activity
BL01_12340	COG1132	(ABC) transporter
BL01_12350	COG0811	peptide transport
BL01_12355	COG1475	DNA binding
BL01_12360	COG1192	Involved in chromosome partitioning
BL01_12370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BL01_12385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BL01_12390	COG0191	fructose-bisphosphate aldolase activity
BL01_12410	COG0424	maF-like protein
BL01_12415	COG2850	peptidyl-arginine hydroxylation
BL01_12425	COG0640	Transcriptional regulator
BL01_12440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BL01_12460	COG2072	flavoprotein involved in K transport
BL01_12470	COG1538	Outer membrane efflux protein
BL01_12475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BL01_12480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BL01_12485	COG0745	RESPONSE REGULATOR receiver
BL01_12490	COG2205	protein histidine kinase activity
BL01_12500	COG2207	Transcriptional regulator
BL01_12515	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_12570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BL01_12615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BL01_12620	COG2011	ABC-type metal ion transport system permease component
BL01_12625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BL01_12630	COG1464	Belongs to the NlpA lipoprotein family
BL01_12635	COG0151	Belongs to the GarS family
BL01_12640	COG0138	bifunctional purine biosynthesis protein purh
BL01_12645	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BL01_12680	COG2308	Evidence 4 Homologs of previously reported genes of
BL01_12690	COG1305	Transglutaminase-like
BL01_12700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BL01_12705	COG0305	Participates in initiation and elongation during chromosome replication
BL01_12730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BL01_12740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BL01_12745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BL01_12765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BL01_12770	COG0280	phosphate acetyltransferase
BL01_12770	COG0857	belongs to the CobB CobQ family
BL01_12775	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BL01_12775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BL01_12795	COG0740	serine-type endopeptidase activity
BL01_12805	COG4774	siderophore transport
BL01_12815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BL01_12825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BL01_12825	COG2813	Specifically methylates the guanine in position
BL01_12925	COG0788	formyltetrahydrofolate deformylase activity
BL01_12940	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BL01_12945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BL01_12950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BL01_12950	COG4651	solute:proton antiporter activity
BL01_12970	COG0724	RNA recognition motif
BL01_12975	COG0210	DNA helicase
BL01_13000	COG1733	regulation of RNA biosynthetic process
BL01_13020	COG1280	lysine exporter protein (LysE YggA)
BL01_13025	COG1560	Kdo2-lipid A biosynthetic process
BL01_13035	COG1301	dicarboxylic acid transport
BL01_13090	COG0473	3-isopropylmalate dehydrogenase activity
BL01_13160	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BL01_13175	COG2807	transmembrane transport
BL01_13180	COG0590	tRNA wobble adenosine to inosine editing
BL01_13190	COG0583	DNA-binding transcription factor activity
BL01_13230	COG2885	chlorophyll binding
BL01_13230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BL01_13295	COG1116	anion transmembrane transporter activity
BL01_13300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BL01_13310	COG0864	Transcriptional regulator
BL01_13330	COG2249	NAD(P)H dehydrogenase (quinone) activity
BL01_13335	COG0439	Biotin carboxylase
BL01_13350	COG1063	alcohol dehydrogenase
BL01_13360	COG1309	transcriptional regulator
BL01_13385	COG0038	chloride channel
BL01_13390	COG4770	biotin carboxylase activity
BL01_13410	COG1914	H( )-stimulated, divalent metal cation uptake system
BL01_13415	COG0583	DNA-binding transcription factor activity
BL01_13430	COG3209	COG3209 Rhs family protein
BL01_13435	COG3501	Rhs element vgr protein
BL01_13460	COG1250	3-hydroxyacyl-CoA dehydrogenase
BL01_13480	COG2814	Major facilitator Superfamily
BL01_13490	COG1560	Kdo2-lipid A biosynthetic process
BL01_13500	COG5006	permease, DMT superfamily
BL01_13505	COG1522	sequence-specific DNA binding
BL01_13525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BL01_13565	COG1538	Outer membrane efflux protein
BL01_13570	COG1137	ATPase activity
BL01_13575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BL01_13585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BL01_13590	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BL01_13590	COG0517	IMP dehydrogenase activity
BL01_13625	COG1733	regulation of RNA biosynthetic process
BL01_13630	COG2814	Major facilitator Superfamily
BL01_13665	COG1278	Cold shock
BL01_13670	COG1280	lysine exporter protein (LysE YggA)
BL01_13705	COG1570	exodeoxyribonuclease VII activity
BL01_13755	COG0583	DNA-binding transcription factor activity
BL01_13760	COG4638	Rieske (2fe-2S)
BL01_13765	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BL01_13770	COG0633	Ferredoxin
BL01_13770	COG0543	2 iron, 2 sulfur cluster binding
BL01_13775	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_13780	COG3135	benzoate transporter
BL01_13785	COG2814	Major facilitator Superfamily
BL01_13800	COG1643	Atp-dependent helicase
BL01_13805	COG0450	alkyl hydroperoxide reductase
BL01_13815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BL01_13825	COG3634	alkyl hydroperoxide reductase activity
BL01_13845	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BL01_13850	COG0625	glutathione transferase activity
BL01_13860	COG2885	chlorophyll binding
BL01_13910	COG1765	OsmC-like protein
BL01_13945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BL01_13950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BL01_13955	COG1752	Esterase of the alpha-beta hydrolase superfamily
BL01_13960	COG1115	amino acid carrier protein
BL01_13980	COG2814	Major facilitator Superfamily
BL01_13985	COG1289	transmembrane transporter activity
BL01_14035	COG1376	ErfK ybiS ycfS ynhG family protein
BL01_14040	COG2832	Protein of unknown function (DUF454)
BL01_14050	COG5510	response to toxic substance
BL01_14070	COG0840	transmembrane signaling receptor activity
BL01_14110	COG3422	double-strand break repair
BL01_14115	COG2824	Alkylphosphonate utilization operon protein PhnA
BL01_14120	COG3189	MarR family transcriptional regulator
BL01_14130	COG0354	folic acid binding
BL01_14135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BL01_14145	COG0679	Auxin Efflux Carrier
BL01_14150	COG1902	pentaerythritol trinitrate reductase activity
BL01_14170	COG3384	dioxygenase
BL01_14180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BL01_14185	COG2878	Part of a membrane complex involved in electron transport
BL01_14190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BL01_14215	COG0768	penicillin binding
BL01_14220	COG0742	ribosomal rna small subunit methyltransferase
BL01_14235	COG0830	nickel cation binding
BL01_14245	COG0804	urea catabolic process
BL01_14290	COG1253	flavin adenine dinucleotide binding
BL01_14300	COG2851	Citrate transporter
BL01_14360	COG0183	Belongs to the thiolase family
BL01_14370	COG0583	DNA-binding transcription factor activity
BL01_14385	COG1522	sequence-specific DNA binding
BL01_14390	COG3135	benzoate transporter
BL01_14400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BL01_14420	COG0589	response to stress
BL01_14425	COG0488	(ABC) transporter
BL01_14445	COG4773	Receptor
BL01_14450	COG2194	sulfuric ester hydrolase activity
BL01_14485	COG0006	proline dipeptidase activity
BL01_14490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BL01_14495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BL01_14515	COG1279	arginine transmembrane transporter activity
BL01_14520	COG0583	DNA-binding transcription factor activity
BL01_14560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BL01_14565	COG0741	lytic transglycosylase activity
BL01_14565	COG1388	LysM domain
BL01_14565	COG0741	lytic transglycosylase activity
BL01_14565	COG1388	LysM domain
BL01_14575	COG4174	ABC transporter (Permease)
BL01_14580	COG4239	(ABC) transporter, permease
BL01_14585	COG4172	Belongs to the ABC transporter superfamily
BL01_14605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BL01_14615	COG2203	Gaf domain
BL01_14615	COG4251	negative regulation of phosphorylation
BL01_14615	COG3706	GGDEF domain
BL01_14615	COG5001	Diguanylate cyclase
BL01_14625	COG1902	pentaerythritol trinitrate reductase activity
BL01_14625	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL01_14760	COG5410	chromosome segregation
BL01_14840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BL01_14865	COG0583	DNA-binding transcription factor activity
BL01_14900	COG2951	lytic endotransglycosylase activity
BL01_14905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BL01_14925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BL01_14935	COG0671	phosphoesterase, PA-phosphatase related
BL01_14940	COG0861	Integral membrane protein TerC family
BL01_14950	COG0754	glutathionylspermidine amidase activity
BL01_14960	COG0402	S-adenosylhomocysteine deaminase activity
BL01_14980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BL01_14985	COG1230	cation diffusion facilitator family transporter
BL01_15000	COG0706	membrane insertase activity
BL01_15015	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BL01_15025	COG0592	DNA-directed DNA polymerase activity
BL01_15035	COG0187	DNA topoisomerase II activity
BL01_15045	COG0586	Pfam SNARE associated Golgi protein
BL01_15050	COG0488	(ABC) transporter
BL01_15075	COG0596	Alpha beta hydrolase
BL01_15080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BL01_15085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BL01_15505	COG1309	transcriptional regulator
BL01_15510	COG1741	Belongs to the pirin family
BL01_15525	COG2072	flavoprotein involved in K transport
BL01_15535	COG2252	PERMEase
BL01_15540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BL01_15545	COG3038	cytochrome b561
BL01_15555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BL01_15575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BL01_15585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BL01_15600	COG0667	Aldo Keto reductase
BL01_15610	COG2199	diguanylate cyclase activity
BL01_15620	COG1408	metallophosphoesterase
BL01_15625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BL01_15635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BL01_15655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BL01_15660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BL01_15675	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BL01_15685	COG2969	positive regulation of protein catabolic process
BL01_15705	COG1960	acyl-CoA dehydrogenase activity
BL01_15710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BL01_15725	COG1309	transcriptional regulator
BL01_15730	COG1960	acyl-CoA dehydrogenase activity
BL01_15765	COG0583	DNA-binding transcription factor activity
BL01_15775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BL01_15785	COG0697	spore germination
BL01_15800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BL01_15810	COG0655	NAD(P)H dehydrogenase (quinone) activity
BL01_15845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BL01_15865	COG1253	flavin adenine dinucleotide binding
BL01_15875	COG2860	membrane
BL01_15880	COG0477	Major facilitator Superfamily
BL01_15890	COG0318	PFAM AMP-dependent synthetase and ligase
BL01_15905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BL01_16000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BL01_16020	COG1120	ATPase activity
BL01_16035	COG1064	alcohol dehydrogenase
BL01_16050	COG2207	Transcriptional regulator
BL01_16055	COG2084	Dehydrogenase
BL01_16065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BL01_16070	COG0583	DNA-binding transcription factor activity
BL01_16080	COG0129	dihydroxy-acid dehydratase activity
BL01_16085	COG1012	belongs to the aldehyde dehydrogenase family
BL01_16105	COG1960	acyl-CoA dehydrogenase activity
BL01_16110	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_16115	COG3829	transcription factor binding
BL01_16125	COG3162	membrane
BL01_16140	COG1012	belongs to the aldehyde dehydrogenase family
BL01_16155	COG0753	catalase activity
BL01_16180	COG1846	Transcriptional regulator
BL01_16185	COG1902	pentaerythritol trinitrate reductase activity
BL01_16185	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL01_16195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BL01_16225	COG1309	transcriptional regulator
BL01_16235	COG1335	isochorismatase
BL01_16240	COG0583	DNA-binding transcription factor activity
BL01_16250	COG0475	glutathione-regulated potassium exporter activity
BL01_16250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BL01_16260	COG1473	amidohydrolase
BL01_16270	COG2831	hemolysin activation secretion protein
BL01_16275	COG3210	domain, Protein
BL01_16325	COG0583	DNA-binding transcription factor activity
BL01_16350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BL01_16355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BL01_16385	COG0308	aminopeptidase N
BL01_16405	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BL01_16415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BL01_16420	COG1454	alcohol dehydrogenase
BL01_16440	COG0531	amino acid
BL01_16445	COG4303	Ethanolamine ammonia lyase large subunit
BL01_16450	COG4302	ethanolamine ammonia-lyase activity
BL01_16455	COG0519	Catalyzes the synthesis of GMP from XMP
BL01_16455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BL01_16470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BL01_16485	COG0697	spore germination
BL01_16510	COG0037	tRNA processing
BL01_16520	COG0248	Ppx GppA phosphatase
BL01_16545	COG0072	phenylalanine-tRNA ligase activity
BL01_16570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BL01_16585	COG1238	metal cluster binding
BL01_16590	COG0625	glutathione transferase activity
BL01_16605	COG0318	PFAM AMP-dependent synthetase and ligase
BL01_16610	COG3028	Belongs to the UPF0307 family
BL01_16615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BL01_16635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BL01_16640	COG0617	tRNA 3'-terminal CCA addition
BL01_16645	COG1555	photosystem II stabilization
BL01_16650	COG3956	TIGRFAM MazG family protein
BL01_16660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BL01_16680	COG0784	Response regulator, receiver
BL01_16680	COG5002	protein histidine kinase activity
BL01_16680	COG2205	protein histidine kinase activity
BL01_16685	COG1024	Enoyl-CoA hydratase
BL01_16690	COG2084	Dehydrogenase
BL01_16695	COG3622	Belongs to the hyi family
BL01_16710	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BL01_16715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BL01_16720	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BL01_16725	COG0697	spore germination
BL01_16735	COG2814	Major facilitator Superfamily
BL01_16740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BL01_16750	COG0583	DNA-binding transcription factor activity
BL01_16755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BL01_16770	COG0084	hydrolase, TatD family'
BL01_16785	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BL01_16815	COG0440	acetolactate synthase activity
BL01_16820	COG0028	Belongs to the TPP enzyme family
BL01_16845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BL01_16850	COG1136	(ABC) transporter
BL01_16850	COG0577	efflux transmembrane transporter activity
BL01_16855	COG1538	Outer membrane efflux protein
BL01_16870	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BL01_16875	COG1162	GTPase activity
BL01_16885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BL01_16905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BL01_16910	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_16950	COG2986	histidine ammonia-lyase
BL01_16965	COG0318	PFAM AMP-dependent synthetase and ligase
BL01_16975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BL01_16980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BL01_17020	COG1426	Protein conserved in bacteria
BL01_17055	COG0793	Belongs to the peptidase S41A family
BL01_17070	COG2267	carboxylic ester hydrolase activity
BL01_17080	COG1012	belongs to the aldehyde dehydrogenase family
BL01_17085	COG3265	gluconokinase activity
BL01_17095	COG0800	Aldolase
BL01_17115	COG0726	polysaccharide deacetylase
BL01_17115	COG1649	PFAM Uncharacterised BCR, COG1649
BL01_17120	COG1215	transferase activity, transferring glycosyl groups
BL01_17125	COG3658	cytochrome
BL01_17135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BL01_17150	COG0583	DNA-binding transcription factor activity
BL01_17170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BL01_17175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BL01_17190	COG1960	acyl-CoA dehydrogenase activity
BL01_17195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BL01_17200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BL01_17225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BL01_17230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BL01_17240	COG2205	protein histidine kinase activity
BL01_17245	COG0745	RESPONSE REGULATOR receiver
BL01_17250	COG0174	glutamine synthetase
BL01_17270	COG0729	surface antigen
BL01_17295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BL01_17300	COG2814	Major facilitator Superfamily
BL01_17315	COG0583	DNA-binding transcription factor activity
BL01_17330	COG1187	pseudouridine synthase activity
BL01_17350	COG0802	atpase or kinase
BL01_17355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BL01_17375	COG0484	heat shock protein binding
BL01_17430	COG1183	phosphatidylcholine synthase activity
BL01_17435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BL01_17465	COG0741	lytic transglycosylase activity
BL01_17465	COG1196	nuclear chromosome segregation
BL01_17465	COG0739	heme binding
BL01_17475	COG1702	phosphate starvation-inducible protein PhoH
BL01_17510	COG1295	ribonuclease BN
BL01_17515	COG0697	spore germination
BL01_17520	COG2169	Transcriptional regulator
BL01_17525	COG0179	Fumarylacetoacetate (FAA) hydrolase
BL01_17630	COG0347	Belongs to the P(II) protein family
BL01_17635	COG0004	ammonium transporteR
BL01_17645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BL01_17645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BL01_17685	COG0795	lipopolysaccharide-transporting ATPase activity
BL01_17690	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BL01_17695	COG0793	Belongs to the peptidase S41A family
BL01_17710	COG2197	response regulator
BL01_17720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BL01_17730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BL01_17735	COG4974	Belongs to the 'phage' integrase family
BL01_17760	COG0772	Belongs to the SEDS family
BL01_17765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BL01_17770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BL01_17775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BL01_17800	COG0697	spore germination
BL01_17805	COG1538	Outer membrane efflux protein
BL01_17825	COG3275	phosphorelay sensor kinase activity
BL01_17835	COG0181	hydroxymethylbilane synthase activity
BL01_17880	COG1716	ATPase activity
BL01_17885	COG0546	phosphoglycolate phosphatase activity
BL01_17990	COG2050	protein possibly involved in aromatic compounds catabolism
BL01_18000	COG3327	negative regulation of DNA-templated transcription, initiation
BL01_18005	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BL01_18010	COG0183	Belongs to the thiolase family
BL01_18015	COG1250	3-hydroxyacyl-CoA dehydrogenase
BL01_18020	COG1024	Enoyl-CoA hydratase
BL01_18025	COG1024	Enoyl-CoA hydratase
BL01_18030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BL01_18035	COG2151	metal-sulfur cluster biosynthetic enzyme
BL01_18040	COG3396	Phenylacetate-CoA oxygenase
BL01_18045	COG3460	Phenylacetate-CoA oxygenase
BL01_18050	COG3396	Phenylacetate-CoA oxygenase
BL01_18055	COG1012	belongs to the aldehyde dehydrogenase family
BL01_18055	COG2030	dehydratase
BL01_18060	COG1760	l-serine dehydratase
BL01_18065	COG0531	amino acid
BL01_18070	COG1012	belongs to the aldehyde dehydrogenase family
BL01_18085	COG0446	pyridine nucleotide-disulphide oxidoreductase
BL01_18095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BL01_18115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BL01_18130	COG0789	Transcriptional regulator
BL01_18145	COG0659	secondary active sulfate transmembrane transporter activity
BL01_18150	COG0589	response to stress
BL01_18170	COG2610	gluconate transmembrane transporter activity
BL01_18175	COG1028	Short-chain dehydrogenase reductase Sdr
BL01_18180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BL01_18190	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BL01_18190	COG0506	proline dehydrogenase activity
BL01_18190	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BL01_18195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BL01_18210	COG3698	Phosphodiester glycosidase
BL01_18220	COG2353	YceI-like domain
BL01_18230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BL01_18275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BL01_18275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BL01_18290	COG4993	Dehydrogenase
BL01_18345	COG3173	Aminoglycoside phosphotransferase
BL01_18385	COG3008	intermembrane lipid transfer
BL01_18385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BL01_18390	COG2995	paraquat-inducible protein a
BL01_18400	COG2985	domain, Protein
BL01_18425	COG0477	Major facilitator Superfamily
BL01_18480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BL01_18490	COG1846	Transcriptional regulator
BL01_18495	COG1764	response to oxidative stress
BL01_18760	COG0833	amino acid
BL01_18795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BL01_18815	COG1132	(ABC) transporter
BL01_18820	COG3122	Protein conserved in bacteria
BL01_18825	COG3619	membrane
BL01_18835	COG3328	transposase activity
BL01_18840	COG3316	Transposase and inactivated derivatives
BL01_18845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BL01_18865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BL01_18870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BL01_18875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BL01_18915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BL01_18955	COG1301	dicarboxylic acid transport
BL01_18960	COG2433	Pfam Transposase IS66
BL01_19045	COG1566	PFAM secretion protein HlyD family protein
BL01_19080	COG3539	Fimbrial protein
BL01_19085	COG3121	Chaperone
BL01_19165	COG3539	Fimbrial protein
BL01_19210	COG0538	isocitrate dehydrogenase activity
BL01_19275	COG4890	Cyd operon protein YbgT
BL01_19375	COG1301	dicarboxylic acid transport
BL01_19385	COG1733	regulation of RNA biosynthetic process
BL01_p0105	COG2963	transposase activity
BL01_p0115	COG4372	Transposase
BL01_p0125	COG3853	Toxic anion resistance protein (TelA)
BL01_p0145	COG1475	DNA binding
BL01_p0210	COG1525	nuclease
BL01_p0360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BL01_p0395	COG0741	lytic transglycosylase activity
BL01_p0465	COG1061	Type III restriction enzyme res subunit
BL01_p0500	COG0668	transmembrane transport
BL01_p0510	COG1309	transcriptional regulator
BL01_p0525	COG1605	Chorismate mutase