locus-tag	class	description
ACICU_00002	COG0187	DNA topoisomerase II activity
ACICU_00004	COG0592	DNA-directed DNA polymerase activity
ACICU_00006	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACICU_00009	COG0706	membrane insertase activity
ACICU_00012	COG1230	cation diffusion facilitator family transporter
ACICU_00013	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACICU_00016	COG0402	S-adenosylhomocysteine deaminase activity
ACICU_00018	COG0754	glutathionylspermidine amidase activity
ACICU_00020	COG0861	Integral membrane protein TerC family
ACICU_00021	COG0671	phosphoesterase, PA-phosphatase related
ACICU_00023	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACICU_00026	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACICU_00027	COG2951	lytic endotransglycosylase activity
ACICU_00033	COG0583	DNA-binding transcription factor activity
ACICU_00037	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACICU_00040	COG1047	Peptidyl-prolyl cis-trans
ACICU_00042	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACICU_00043	COG0196	riboflavin kinase activity
ACICU_00045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACICU_00046	COG1309	transcriptional regulator
ACICU_00047	COG1116	anion transmembrane transporter activity
ACICU_00048	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACICU_00049	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACICU_00050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACICU_00051	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACICU_00055	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_00056	COG0546	phosphoglycolate phosphatase activity
ACICU_00067	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACICU_00068	COG0728	peptidoglycan biosynthetic process
ACICU_00073	COG1596	polysaccharide export
ACICU_00074	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACICU_00075	COG1086	Polysaccharide biosynthesis protein
ACICU_00076	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACICU_00077	COG1083	cytidylyl-transferase
ACICU_00080	COG2089	acid synthase
ACICU_00086	COG1216	Glycosyl transferase, family 2
ACICU_00087	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACICU_00088	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACICU_00091	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACICU_00092	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACICU_00094	COG2186	Transcriptional regulator
ACICU_00096	COG0277	FAD linked oxidase domain protein
ACICU_00097	COG1448	Aminotransferase
ACICU_00098	COG1802	Transcriptional regulator
ACICU_00101	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACICU_00117	COG0564	pseudouridine synthase activity
ACICU_00122	COG1522	sequence-specific DNA binding
ACICU_00125	COG0251	oxidation-reduction process
ACICU_00126	COG1113	amino acid transport
ACICU_00127	COG1113	amino acid transport
ACICU_00131	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACICU_00132	COG1960	acyl-CoA dehydrogenase activity
ACICU_00133	COG1024	Enoyl-CoA hydratase
ACICU_00134	COG1024	Enoyl-CoA hydratase
ACICU_00135	COG0477	Major facilitator Superfamily
ACICU_00136	COG3916	Acyl-homoserine-lactone synthase
ACICU_00138	COG2197	response regulator
ACICU_00140	COG1960	acyl-CoA dehydrogenase activity
ACICU_00141	COG3321	synthase
ACICU_00141	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ACICU_00141	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACICU_00141	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACICU_00147	COG0271	Belongs to the BolA IbaG family
ACICU_00149	COG1192	Involved in chromosome partitioning
ACICU_00152	COG0586	Pfam SNARE associated Golgi protein
ACICU_00153	COG2259	Doxx family
ACICU_00154	COG4399	Belongs to the UPF0754 family
ACICU_00155	COG0519	Catalyzes the synthesis of GMP from XMP
ACICU_00155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACICU_00164	COG0281	malic enzyme
ACICU_00165	COG2837	iron assimilation
ACICU_00166	COG1280	lysine exporter protein (LysE YggA)
ACICU_00167	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACICU_00168	COG1121	(ABC) transporter
ACICU_00182	COG0386	Belongs to the glutathione peroxidase family
ACICU_00185	COG1309	transcriptional regulator
ACICU_00186	COG0697	spore germination
ACICU_00188	COG0758	DNA mediated transformation
ACICU_00195	COG1309	transcriptional regulator
ACICU_00197	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACICU_00199	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACICU_00206	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACICU_00208	COG2814	Major facilitator Superfamily
ACICU_00210	COG1253	flavin adenine dinucleotide binding
ACICU_00211	COG3012	SEC-C Motif Domain Protein
ACICU_00212	COG2860	membrane
ACICU_00213	COG0477	Major facilitator Superfamily
ACICU_00215	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_00218	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACICU_00231	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACICU_00234	COG0789	Transcriptional regulator
ACICU_00239	COG0659	secondary active sulfate transmembrane transporter activity
ACICU_00241	COG0606	chelatase, subunit chli
ACICU_00243	COG0347	Belongs to the P(II) protein family
ACICU_00244	COG0004	ammonium transporteR
ACICU_00246	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACICU_00246	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACICU_00254	COG0795	lipopolysaccharide-transporting ATPase activity
ACICU_00255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACICU_00256	COG0793	Belongs to the peptidase S41A family
ACICU_00259	COG2197	response regulator
ACICU_00261	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACICU_00263	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACICU_00264	COG4974	Belongs to the 'phage' integrase family
ACICU_00269	COG0772	Belongs to the SEDS family
ACICU_00270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACICU_00271	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACICU_00272	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACICU_00277	COG0697	spore germination
ACICU_00278	COG1538	Outer membrane efflux protein
ACICU_00282	COG3275	phosphorelay sensor kinase activity
ACICU_00284	COG0181	hydroxymethylbilane synthase activity
ACICU_00293	COG1716	ATPase activity
ACICU_00294	COG0546	phosphoglycolate phosphatase activity
ACICU_00308	COG0596	Alpha beta hydrolase
ACICU_00309	COG2056	Na+-H+ antiporter family
ACICU_00312	COG0326	Molecular chaperone. Has ATPase activity
ACICU_00315	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACICU_00328	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACICU_00329	COG2169	Transcriptional regulator
ACICU_00329	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACICU_00335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACICU_00337	COG0497	DNA recombination
ACICU_00340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACICU_00342	COG0237	dephospho-CoA kinase activity
ACICU_00349	COG0195	Participates in both transcription termination and antitermination
ACICU_00353	COG2212	antiporter activity
ACICU_00355	COG0651	ATP synthesis coupled electron transport
ACICU_00356	COG1006	Multisubunit Na H antiporter MnhC subunit
ACICU_00357	COG2111	Na H antiporter
ACICU_00357	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACICU_00360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACICU_00361	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_00364	COG2226	methyltransferase
ACICU_00368	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACICU_00369	COG1074	ATP-dependent DNA helicase activity
ACICU_00370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACICU_00374	COG0598	Magnesium transport protein CorA
ACICU_00375	COG0789	Transcriptional regulator
ACICU_00376	COG0484	heat shock protein binding
ACICU_00378	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACICU_00379	COG0475	glutathione-regulated potassium exporter activity
ACICU_00379	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACICU_00380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACICU_00384	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACICU_00386	COG4535	Mg2 and Co2 transporter CorC
ACICU_00387	COG0425	Belongs to the sulfur carrier protein TusA family
ACICU_00388	COG0644	oxidoreductase
ACICU_00388	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACICU_00390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACICU_00393	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_00394	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACICU_00401	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACICU_00404	COG0534	Mate efflux family protein
ACICU_00406	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACICU_00407	COG4221	oxidoreductase activity
ACICU_00408	COG0583	DNA-binding transcription factor activity
ACICU_00410	COG1530	ribonuclease E activity
ACICU_00412	COG0546	phosphoglycolate phosphatase activity
ACICU_00413	COG2378	regulation of single-species biofilm formation
ACICU_00414	COG0625	glutathione transferase activity
ACICU_00416	COG0583	DNA-binding transcription factor activity
ACICU_00428	COG0473	3-isopropylmalate dehydrogenase activity
ACICU_00439	COG1301	dicarboxylic acid transport
ACICU_00441	COG1560	Kdo2-lipid A biosynthetic process
ACICU_00442	COG1280	lysine exporter protein (LysE YggA)
ACICU_00446	COG1733	regulation of RNA biosynthetic process
ACICU_00451	COG0210	DNA helicase
ACICU_00452	COG0724	RNA recognition motif
ACICU_00456	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACICU_00456	COG4651	solute:proton antiporter activity
ACICU_00457	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACICU_00458	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACICU_00461	COG0788	formyltetrahydrofolate deformylase activity
ACICU_00481	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACICU_00481	COG2813	Specifically methylates the guanine in position
ACICU_00483	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACICU_00485	COG4774	siderophore transport
ACICU_00487	COG0740	serine-type endopeptidase activity
ACICU_00491	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACICU_00491	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACICU_00492	COG0857	belongs to the CobB CobQ family
ACICU_00492	COG0280	phosphate acetyltransferase
ACICU_00493	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACICU_00495	COG0800	Aldolase
ACICU_00497	COG3265	gluconokinase activity
ACICU_00498	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_00500	COG2267	carboxylic ester hydrolase activity
ACICU_00503	COG0793	Belongs to the peptidase S41A family
ACICU_00510	COG1426	Protein conserved in bacteria
ACICU_00519	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACICU_00520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACICU_00522	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_00525	COG2986	histidine ammonia-lyase
ACICU_00533	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_00534	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACICU_00538	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACICU_00540	COG1162	GTPase activity
ACICU_00541	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACICU_00544	COG1538	Outer membrane efflux protein
ACICU_00545	COG0577	efflux transmembrane transporter activity
ACICU_00545	COG1136	(ABC) transporter
ACICU_00546	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_00551	COG0028	Belongs to the TPP enzyme family
ACICU_00552	COG0440	acetolactate synthase activity
ACICU_00558	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACICU_00561	COG0084	hydrolase, TatD family'
ACICU_00564	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACICU_00565	COG0583	DNA-binding transcription factor activity
ACICU_00567	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACICU_00568	COG2814	Major facilitator Superfamily
ACICU_00570	COG0697	spore germination
ACICU_00571	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACICU_00572	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACICU_00573	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACICU_00576	COG3622	Belongs to the hyi family
ACICU_00577	COG2084	Dehydrogenase
ACICU_00578	COG1024	Enoyl-CoA hydratase
ACICU_00579	COG0784	Response regulator, receiver
ACICU_00579	COG5002	protein histidine kinase activity
ACICU_00579	COG2205	protein histidine kinase activity
ACICU_00583	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACICU_00585	COG3956	TIGRFAM MazG family protein
ACICU_00586	COG1555	photosystem II stabilization
ACICU_00587	COG0617	tRNA 3'-terminal CCA addition
ACICU_00588	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACICU_00592	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACICU_00593	COG3028	Belongs to the UPF0307 family
ACICU_00594	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_00597	COG0625	glutathione transferase activity
ACICU_00598	COG1238	metal cluster binding
ACICU_00601	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACICU_00606	COG0072	phenylalanine-tRNA ligase activity
ACICU_00611	COG0248	Ppx GppA phosphatase
ACICU_00613	COG0037	tRNA processing
ACICU_00621	COG1764	response to oxidative stress
ACICU_00622	COG1846	Transcriptional regulator
ACICU_00623	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACICU_00630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACICU_00631	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACICU_00632	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACICU_00634	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACICU_00644	COG1214	PFAM Peptidase M22, glycoprotease
ACICU_00649	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACICU_00650	COG0561	phosphatase activity
ACICU_00652	COG2132	Multicopper oxidase
ACICU_00653	COG3667	copper resistance
ACICU_00656	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACICU_00657	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACICU_00658	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACICU_00660	COG1063	alcohol dehydrogenase
ACICU_00661	COG0583	DNA-binding transcription factor activity
ACICU_00662	COG1960	acyl-CoA dehydrogenase activity
ACICU_00663	COG2814	Major facilitator Superfamily
ACICU_00664	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACICU_00666	COG1053	succinate dehydrogenase
ACICU_00667	COG0583	DNA-binding transcription factor activity
ACICU_00670	COG0583	DNA-binding transcription factor activity
ACICU_00672	COG1473	amidohydrolase
ACICU_00675	COG1280	lysine exporter protein (LysE YggA)
ACICU_00676	COG0583	DNA-binding transcription factor activity
ACICU_00678	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACICU_00679	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_00683	COG0384	phenazine biosynthesis protein PhzF
ACICU_00685	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_00688	COG4993	Dehydrogenase
ACICU_00700	COG2205	protein histidine kinase activity
ACICU_00702	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACICU_00705	COG0745	RESPONSE REGULATOR receiver
ACICU_00706	COG2205	protein histidine kinase activity
ACICU_00713	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACICU_00719	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACICU_00720	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACICU_00724	COG0583	DNA-binding transcription factor activity
ACICU_00728	COG0668	transmembrane transport
ACICU_00730	COG2081	HI0933 family
ACICU_00731	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ACICU_00737	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACICU_00737	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACICU_00739	COG0489	protein tyrosine kinase activity
ACICU_00749	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACICU_00751	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACICU_00754	COG0730	response to heat
ACICU_00756	COG1196	nuclear chromosome segregation
ACICU_00760	COG2223	nitrite transmembrane transporter activity
ACICU_00761	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACICU_00762	COG1877	trehalose-phosphatase activity
ACICU_00763	COG0596	Alpha beta hydrolase
ACICU_00763	COG2226	methyltransferase
ACICU_00763	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACICU_00766	COG4106	trans-aconitate 2-methyltransferase activity
ACICU_00769	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACICU_00770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACICU_00771	COG0009	L-threonylcarbamoyladenylate synthase
ACICU_00772	COG3101	peptidyl-lysine hydroxylation
ACICU_00773	COG1399	metal-binding, possibly nucleic acid-binding protein
ACICU_00778	COG1652	LysM domain
ACICU_00779	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACICU_00779	COG0351	phosphomethylpyrimidine kinase
ACICU_00779	COG0352	thiamine-phosphate diphosphorylase activity
ACICU_00781	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACICU_00787	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACICU_00789	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACICU_00792	COG0358	DNA primase activity
ACICU_00799	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACICU_00801	COG0583	DNA-binding transcription factor activity
ACICU_00802	COG0473	3-isopropylmalate dehydrogenase activity
ACICU_00806	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_00809	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACICU_00809	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACICU_00821	COG0456	acetyltransferase
ACICU_00823	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACICU_00824	COG0492	ferredoxin-NADP+ reductase activity
ACICU_00825	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACICU_00825	COG1674	ftsk spoiiie
ACICU_00826	COG1280	lysine exporter protein (LysE YggA)
ACICU_00831	COG2894	cell division
ACICU_00834	COG0204	Acyl-transferase
ACICU_00835	COG2885	chlorophyll binding
ACICU_00836	COG0210	DNA helicase
ACICU_00838	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACICU_00841	COG0121	glutamine amidotransferase
ACICU_00845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACICU_00846	COG0735	belongs to the Fur family
ACICU_00851	COG0420	3'-5' exonuclease activity
ACICU_00855	COG1090	epimerase
ACICU_00858	COG2050	protein possibly involved in aromatic compounds catabolism
ACICU_00860	COG2814	Major facilitator Superfamily
ACICU_00861	COG0405	Gamma-glutamyltransferase
ACICU_00867	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_00870	COG0477	Major facilitator Superfamily
ACICU_00871	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACICU_00873	COG1595	DNA-templated transcription, initiation
ACICU_00884	COG0531	amino acid
ACICU_00885	COG2040	homocysteine
ACICU_00890	COG1309	transcriptional regulator
ACICU_00891	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_00892	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_00894	COG1607	acyl-coa hydrolase
ACICU_00896	COG0523	cobalamin synthesis protein
ACICU_00898	COG4681	YaeQ
ACICU_00900	COG1649	PFAM Uncharacterised BCR, COG1649
ACICU_00900	COG0726	polysaccharide deacetylase
ACICU_00901	COG1215	transferase activity, transferring glycosyl groups
ACICU_00903	COG1024	Enoyl-CoA hydratase
ACICU_00906	COG1414	Transcriptional regulator
ACICU_00910	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_00912	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_00913	COG2271	Major facilitator Superfamily
ACICU_00915	COG2267	carboxylic ester hydrolase activity
ACICU_00916	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_00919	COG0028	Belongs to the TPP enzyme family
ACICU_00921	COG0477	Major facilitator Superfamily
ACICU_00922	COG0242	peptide deformylase activity
ACICU_00923	COG2066	Belongs to the glutaminase family
ACICU_00924	COG2207	Transcriptional regulator
ACICU_00925	COG2223	nitrite transmembrane transporter activity
ACICU_00928	COG0583	DNA-binding transcription factor activity
ACICU_00929	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_00930	COG2271	Major facilitator Superfamily
ACICU_00931	COG3959	Transketolase, thiamine diphosphate binding domain
ACICU_00932	COG3958	Transketolase
ACICU_00934	COG0306	phosphate transporter
ACICU_00938	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACICU_00947	COG4181	ATPase activity
ACICU_00948	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACICU_00953	COG0583	DNA-binding transcription factor activity
ACICU_00955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_00956	COG1773	rubredoxin
ACICU_00965	COG2851	Citrate transporter
ACICU_00966	COG1253	flavin adenine dinucleotide binding
ACICU_00974	COG0804	urea catabolic process
ACICU_00975	COG0804	urea catabolic process
ACICU_00977	COG0830	nickel cation binding
ACICU_00980	COG0742	ribosomal rna small subunit methyltransferase
ACICU_00981	COG0768	penicillin binding
ACICU_00986	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACICU_00987	COG2878	Part of a membrane complex involved in electron transport
ACICU_00988	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACICU_00990	COG3384	dioxygenase
ACICU_00995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACICU_01072	COG2194	sulfuric ester hydrolase activity
ACICU_01079	COG0006	proline dipeptidase activity
ACICU_01080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_01081	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_01085	COG1279	arginine transmembrane transporter activity
ACICU_01086	COG0583	DNA-binding transcription factor activity
ACICU_01094	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACICU_01095	COG0741	lytic transglycosylase activity
ACICU_01095	COG1388	LysM domain
ACICU_01095	COG1388	LysM domain
ACICU_01095	COG0741	lytic transglycosylase activity
ACICU_01097	COG4174	ABC transporter (Permease)
ACICU_01098	COG4239	(ABC) transporter, permease
ACICU_01099	COG4172	Belongs to the ABC transporter superfamily
ACICU_01102	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACICU_01104	COG3706	GGDEF domain
ACICU_01104	COG2203	Gaf domain
ACICU_01104	COG4251	negative regulation of phosphorylation
ACICU_01104	COG5001	Diguanylate cyclase
ACICU_01106	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_01106	COG1902	pentaerythritol trinitrate reductase activity
ACICU_01109	COG4269	membrane
ACICU_01116	COG3501	Rhs element vgr protein
ACICU_01118	COG3209	COG3209 Rhs family protein
ACICU_01127	COG1113	amino acid transport
ACICU_01129	COG0531	amino acid
ACICU_01133	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01137	COG1113	amino acid transport
ACICU_01141	COG1309	transcriptional regulator
ACICU_01142	COG1741	Belongs to the pirin family
ACICU_01145	COG2072	flavoprotein involved in K transport
ACICU_01147	COG2252	PERMEase
ACICU_01148	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACICU_01149	COG3038	cytochrome b561
ACICU_01151	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACICU_01155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACICU_01157	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACICU_01160	COG0667	Aldo Keto reductase
ACICU_01162	COG1765	OsmC-like protein
ACICU_01172	COG2885	chlorophyll binding
ACICU_01174	COG0625	glutathione transferase activity
ACICU_01175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACICU_01179	COG3634	alkyl hydroperoxide reductase activity
ACICU_01181	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACICU_01183	COG0450	alkyl hydroperoxide reductase
ACICU_01184	COG1643	Atp-dependent helicase
ACICU_01187	COG2814	Major facilitator Superfamily
ACICU_01188	COG3135	benzoate transporter
ACICU_01189	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01190	COG0633	Ferredoxin
ACICU_01190	COG0543	2 iron, 2 sulfur cluster binding
ACICU_01191	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACICU_01192	COG4638	Rieske (2fe-2S)
ACICU_01193	COG0583	DNA-binding transcription factor activity
ACICU_01203	COG1570	exodeoxyribonuclease VII activity
ACICU_01209	COG1280	lysine exporter protein (LysE YggA)
ACICU_01210	COG1278	Cold shock
ACICU_01217	COG2814	Major facilitator Superfamily
ACICU_01218	COG1733	regulation of RNA biosynthetic process
ACICU_01225	COG0517	IMP dehydrogenase activity
ACICU_01225	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACICU_01226	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACICU_01228	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACICU_01229	COG1137	ATPase activity
ACICU_01230	COG1538	Outer membrane efflux protein
ACICU_01238	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACICU_01242	COG1522	sequence-specific DNA binding
ACICU_01243	COG1522	sequence-specific DNA binding
ACICU_01247	COG5006	permease, DMT superfamily
ACICU_01249	COG1560	Kdo2-lipid A biosynthetic process
ACICU_01252	COG2814	Major facilitator Superfamily
ACICU_01256	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACICU_01261	COG3501	Rhs element vgr protein
ACICU_01262	COG3209	COG3209 Rhs family protein
ACICU_01265	COG0583	DNA-binding transcription factor activity
ACICU_01266	COG1914	H( )-stimulated, divalent metal cation uptake system
ACICU_01271	COG4770	biotin carboxylase activity
ACICU_01272	COG0038	chloride channel
ACICU_01277	COG1309	transcriptional regulator
ACICU_01280	COG1063	alcohol dehydrogenase
ACICU_01283	COG0439	Biotin carboxylase
ACICU_01284	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACICU_01285	COG1733	regulation of RNA biosynthetic process
ACICU_01288	COG0864	Transcriptional regulator
ACICU_01290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACICU_01291	COG1116	anion transmembrane transporter activity
ACICU_01305	COG2885	chlorophyll binding
ACICU_01305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACICU_01313	COG0583	DNA-binding transcription factor activity
ACICU_01315	COG0590	tRNA wobble adenosine to inosine editing
ACICU_01316	COG2807	transmembrane transport
ACICU_01319	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACICU_01321	COG0789	Transcriptional regulator
ACICU_01323	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACICU_01327	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACICU_01329	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_01332	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01333	COG0531	amino acid
ACICU_01334	COG1760	l-serine dehydratase
ACICU_01335	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01335	COG2030	dehydratase
ACICU_01336	COG3396	Phenylacetate-CoA oxygenase
ACICU_01337	COG3460	Phenylacetate-CoA oxygenase
ACICU_01338	COG3396	Phenylacetate-CoA oxygenase
ACICU_01339	COG2151	metal-sulfur cluster biosynthetic enzyme
ACICU_01340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACICU_01341	COG1024	Enoyl-CoA hydratase
ACICU_01342	COG1024	Enoyl-CoA hydratase
ACICU_01343	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACICU_01344	COG0183	Belongs to the thiolase family
ACICU_01345	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ACICU_01346	COG3327	negative regulation of DNA-templated transcription, initiation
ACICU_01348	COG2050	protein possibly involved in aromatic compounds catabolism
ACICU_01356	COG0753	catalase activity
ACICU_01357	COG3038	cytochrome b561
ACICU_01361	COG2267	carboxylic ester hydrolase activity
ACICU_01362	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_01363	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACICU_01364	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01366	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACICU_01368	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01369	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACICU_01371	COG0583	DNA-binding transcription factor activity
ACICU_01373	COG1414	Transcriptional regulator
ACICU_01374	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_01376	COG1840	ABC-type Fe3 transport system, periplasmic component
ACICU_01377	COG3842	ATPase activity
ACICU_01380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACICU_01381	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACICU_01382	COG2814	Major facilitator Superfamily
ACICU_01383	COG1960	acyl-CoA dehydrogenase activity
ACICU_01386	COG1024	Enoyl-CoA hydratase
ACICU_01389	COG2814	Major facilitator Superfamily
ACICU_01391	COG0183	Belongs to the thiolase family
ACICU_01392	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACICU_01393	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01394	COG1024	Enoyl-CoA hydratase
ACICU_01395	COG1960	acyl-CoA dehydrogenase activity
ACICU_01396	COG2814	Major facilitator Superfamily
ACICU_01397	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACICU_01398	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACICU_01400	COG2814	Major facilitator Superfamily
ACICU_01401	COG2814	Major facilitator Superfamily
ACICU_01403	COG1960	acyl-CoA dehydrogenase activity
ACICU_01406	COG0583	DNA-binding transcription factor activity
ACICU_01409	COG1024	Enoyl-CoA hydratase
ACICU_01410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACICU_01411	COG1960	acyl-CoA dehydrogenase activity
ACICU_01412	COG1309	transcriptional regulator
ACICU_01413	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_01417	COG0583	DNA-binding transcription factor activity
ACICU_01427	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01431	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACICU_01435	COG0784	Response regulator, receiver
ACICU_01435	COG2205	protein histidine kinase activity
ACICU_01438	COG0765	amino acid transport
ACICU_01439	COG0765	amino acid transport
ACICU_01440	COG1126	abc transporter atp-binding protein
ACICU_01441	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACICU_01442	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACICU_01444	COG1280	lysine exporter protein (LysE YggA)
ACICU_01445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACICU_01446	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACICU_01447	COG1045	serine acetyltransferase
ACICU_01450	COG0583	DNA-binding transcription factor activity
ACICU_01451	COG0625	glutathione transferase activity
ACICU_01452	COG0625	glutathione transferase activity
ACICU_01453	COG0583	DNA-binding transcription factor activity
ACICU_01455	COG1346	cytolysis
ACICU_01459	COG2814	Major facilitator Superfamily
ACICU_01461	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ACICU_01462	COG3052	prosthetic group binding
ACICU_01466	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACICU_01470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACICU_01472	COG1294	oxidase, subunit
ACICU_01473	COG1271	oxidase subunit
ACICU_01479	COG0477	Major facilitator Superfamily
ACICU_01481	COG4521	taurine ABC transporter
ACICU_01482	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACICU_01483	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACICU_01484	COG2175	clavaminate synthase activity
ACICU_01486	COG1953	Uracil, thiamine, allantoin
ACICU_01488	COG0583	DNA-binding transcription factor activity
ACICU_01490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACICU_01493	COG0640	Transcriptional regulator
ACICU_01494	COG0798	PFAM Bile acid sodium symporter
ACICU_01495	COG0583	DNA-binding transcription factor activity
ACICU_01498	COG3634	alkyl hydroperoxide reductase activity
ACICU_01506	COG0436	Aminotransferase
ACICU_01508	COG0386	Belongs to the glutathione peroxidase family
ACICU_01516	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACICU_01521	COG0012	GTP binding
ACICU_01522	COG2011	ABC-type metal ion transport system permease component
ACICU_01523	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACICU_01525	COG1464	Belongs to the NlpA lipoprotein family
ACICU_01531	COG0765	amino acid transport
ACICU_01532	COG0765	amino acid transport
ACICU_01533	COG1126	abc transporter atp-binding protein
ACICU_01535	COG1522	sequence-specific DNA binding
ACICU_01538	COG1309	transcriptional regulator
ACICU_01541	COG0583	DNA-binding transcription factor activity
ACICU_01543	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACICU_01545	COG0697	spore germination
ACICU_01550	COG3121	Chaperone
ACICU_01551	COG3539	Fimbrial protein
ACICU_01556	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACICU_01556	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACICU_01566	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACICU_01568	COG2353	YceI-like domain
ACICU_01573	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACICU_01574	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACICU_01574	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACICU_01574	COG0506	proline dehydrogenase activity
ACICU_01576	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACICU_01577	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACICU_01581	COG1132	(ABC) transporter
ACICU_01582	COG3122	Protein conserved in bacteria
ACICU_01583	COG3619	membrane
ACICU_01585	COG0640	Transcriptional regulator
ACICU_01587	COG2850	peptidyl-arginine hydroxylation
ACICU_01588	COG0424	maF-like protein
ACICU_01592	COG0191	fructose-bisphosphate aldolase activity
ACICU_01593	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACICU_01596	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACICU_01598	COG1192	Involved in chromosome partitioning
ACICU_01599	COG1475	DNA binding
ACICU_01600	COG0811	peptide transport
ACICU_01602	COG1132	(ABC) transporter
ACICU_01603	COG1663	tetraacyldisaccharide 4'-kinase activity
ACICU_01607	COG0084	hydrolase, TatD family'
ACICU_01610	COG2165	general secretion pathway protein
ACICU_01616	COG0590	tRNA wobble adenosine to inosine editing
ACICU_01620	COG0776	regulation of translation
ACICU_01626	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACICU_01627	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACICU_01636	COG0339	signal peptide processing
ACICU_01638	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACICU_01645	COG0702	epimerase
ACICU_01646	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACICU_01650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACICU_01657	COG0316	Belongs to the HesB IscA family
ACICU_01658	COG0822	iron-sulfur transferase activity
ACICU_01663	COG0776	regulation of translation
ACICU_01664	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACICU_01665	COG2207	Transcriptional regulator
ACICU_01666	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACICU_01667	COG1960	acyl-CoA dehydrogenase activity
ACICU_01668	COG1960	acyl-CoA dehydrogenase activity
ACICU_01671	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACICU_01675	COG4264	IucA IucC family
ACICU_01676	COG4264	IucA IucC family
ACICU_01684	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACICU_01687	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACICU_01691	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACICU_01692	COG0730	response to heat
ACICU_01696	COG4773	Receptor
ACICU_01697	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACICU_01700	COG1131	(ABC) transporter
ACICU_01701	COG0842	Transport permease protein
ACICU_01702	COG0842	Transport permease protein
ACICU_01714	COG2226	methyltransferase
ACICU_01719	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACICU_01726	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACICU_01728	COG0133	tryptophan synthase activity
ACICU_01731	COG3706	GGDEF domain
ACICU_01734	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACICU_01735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACICU_01736	COG0022	dehydrogenase e1 component
ACICU_01737	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACICU_01738	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACICU_01740	COG1063	alcohol dehydrogenase
ACICU_01741	COG3781	membrane
ACICU_01743	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_01743	COG3453	Protein conserved in bacteria
ACICU_01745	COG0730	response to heat
ACICU_01748	COG2207	Transcriptional regulator
ACICU_01748	COG3708	Transcriptional regulator
ACICU_01749	COG1733	regulation of RNA biosynthetic process
ACICU_01750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACICU_01755	COG4521	taurine ABC transporter
ACICU_01756	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACICU_01760	COG0477	Major facilitator Superfamily
ACICU_01762	COG1027	Aspartate ammonia-lyase
ACICU_01765	COG0583	DNA-binding transcription factor activity
ACICU_01766	COG0583	DNA-binding transcription factor activity
ACICU_01767	COG0183	Belongs to the thiolase family
ACICU_01768	COG2031	fatty acid transporter
ACICU_01769	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACICU_01771	COG0583	DNA-binding transcription factor activity
ACICU_01773	COG2610	gluconate transmembrane transporter activity
ACICU_01774	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01775	COG2207	Transcriptional regulator
ACICU_01777	COG0412	Dienelactone hydrolase
ACICU_01778	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_01783	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACICU_01783	COG0543	2 iron, 2 sulfur cluster binding
ACICU_01784	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACICU_01785	COG4638	Rieske (2fe-2S)
ACICU_01787	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACICU_01788	COG4149	molybdate abc transporter
ACICU_01789	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACICU_01790	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01791	COG3433	isochorismatase activity
ACICU_01791	COG1535	isochorismatase
ACICU_01803	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACICU_01806	COG0753	catalase activity
ACICU_01808	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACICU_01813	COG3539	Fimbrial protein
ACICU_01817	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACICU_01821	COG2072	flavoprotein involved in K transport
ACICU_01823	COG1538	Outer membrane efflux protein
ACICU_01824	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACICU_01825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_01826	COG0745	RESPONSE REGULATOR receiver
ACICU_01827	COG2205	protein histidine kinase activity
ACICU_01829	COG2207	Transcriptional regulator
ACICU_01832	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01843	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACICU_01869	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACICU_01873	COG1120	ATPase activity
ACICU_01877	COG1064	alcohol dehydrogenase
ACICU_01880	COG2207	Transcriptional regulator
ACICU_01881	COG2084	Dehydrogenase
ACICU_01883	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACICU_01884	COG0583	DNA-binding transcription factor activity
ACICU_01886	COG0129	dihydroxy-acid dehydratase activity
ACICU_01887	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01890	COG1566	PFAM secretion protein HlyD family protein
ACICU_01894	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACICU_01895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACICU_01900	COG0583	DNA-binding transcription factor activity
ACICU_01911	COG3210	domain, Protein
ACICU_01912	COG2831	hemolysin activation secretion protein
ACICU_01914	COG1473	amidohydrolase
ACICU_01916	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACICU_01916	COG0475	glutathione-regulated potassium exporter activity
ACICU_01918	COG0583	DNA-binding transcription factor activity
ACICU_01919	COG1335	isochorismatase
ACICU_01921	COG1309	transcriptional regulator
ACICU_01927	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACICU_01929	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_01929	COG1902	pentaerythritol trinitrate reductase activity
ACICU_01930	COG1846	Transcriptional regulator
ACICU_01934	COG0753	catalase activity
ACICU_01937	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01940	COG3162	membrane
ACICU_01942	COG3829	transcription factor binding
ACICU_01943	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01945	COG1960	acyl-CoA dehydrogenase activity
ACICU_01949	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01953	COG2186	Transcriptional regulator
ACICU_01955	COG0583	DNA-binding transcription factor activity
ACICU_01956	COG4948	Mandelate Racemase Muconate Lactonizing
ACICU_01957	COG4829	muconolactone delta-isomerase
ACICU_01959	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACICU_01960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACICU_01961	COG0183	Belongs to the thiolase family
ACICU_01962	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACICU_01964	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_01966	COG3733	amine oxidase
ACICU_01968	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_01970	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_01972	COG4638	Rieske (2fe-2S)
ACICU_01976	COG0154	amidase activity
ACICU_01978	COG2814	Major facilitator Superfamily
ACICU_01983	COG1960	acyl-CoA dehydrogenase activity
ACICU_01984	COG0583	DNA-binding transcription factor activity
ACICU_01985	COG1414	Transcriptional regulator
ACICU_01988	COG2391	methyltransferase activity
ACICU_01990	COG4993	Dehydrogenase
ACICU_01991	COG3659	wide pore channel activity
ACICU_01992	COG3420	alginic acid biosynthetic process
ACICU_01993	COG0710	3-dehydroquinate dehydratase activity
ACICU_01994	COG3485	protocatechuate 3,4-dioxygenase
ACICU_01995	COG3485	protocatechuate 3,4-dioxygenase
ACICU_01996	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACICU_01997	COG2271	Major facilitator Superfamily
ACICU_01998	COG0596	Alpha beta hydrolase
ACICU_01999	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACICU_02000	COG0183	Belongs to the thiolase family
ACICU_02001	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACICU_02002	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACICU_02003	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACICU_02005	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACICU_02006	COG2323	membrane
ACICU_02015	COG1902	pentaerythritol trinitrate reductase activity
ACICU_02015	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_02018	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACICU_02020	COG0542	response to heat
ACICU_02021	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACICU_02027	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACICU_02028	COG0569	domain protein
ACICU_02029	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACICU_02032	COG4774	siderophore transport
ACICU_02033	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACICU_02035	COG1585	Membrane protein implicated in regulation of membrane protease activity
ACICU_02040	COG1294	oxidase, subunit
ACICU_02043	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ACICU_02045	COG0552	protein localization to endoplasmic reticulum
ACICU_02050	COG0516	GMP reductase activity
ACICU_02050	COG0517	IMP dehydrogenase activity
ACICU_02051	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACICU_02052	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACICU_02054	COG0583	DNA-binding transcription factor activity
ACICU_02055	COG0024	Methionine aminopeptidase
ACICU_02061	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACICU_02061	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACICU_02062	COG1105	Belongs to the carbohydrate kinase PfkB family
ACICU_02063	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACICU_02063	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACICU_02063	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACICU_02068	COG5001	Diguanylate cyclase
ACICU_02068	COG3300	MHYT domain
ACICU_02071	COG2135	peptidase activity
ACICU_02072	COG0659	secondary active sulfate transmembrane transporter activity
ACICU_02075	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_02076	COG1113	amino acid transport
ACICU_02078	COG1522	sequence-specific DNA binding
ACICU_02083	COG1011	Hydrolase
ACICU_02084	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACICU_02086	COG2137	regulation of response to DNA damage stimulus
ACICU_02088	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACICU_02095	COG0575	Belongs to the CDS family
ACICU_02096	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACICU_02100	COG3852	Histidine kinase
ACICU_02101	COG2204	response regulator
ACICU_02113	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACICU_02114	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACICU_02118	COG0697	spore germination
ACICU_02119	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACICU_02121	COG0303	'Molybdopterin
ACICU_02122	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACICU_02122	COG0315	cyclic pyranopterin monophosphate synthase activity
ACICU_02125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACICU_02126	COG0243	molybdopterin cofactor binding
ACICU_02128	COG0243	molybdopterin cofactor binding
ACICU_02129	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_02130	COG2146	nitrite reductase [NAD(P)H] activity
ACICU_02130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_02132	COG0745	RESPONSE REGULATOR receiver
ACICU_02133	COG1116	anion transmembrane transporter activity
ACICU_02133	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACICU_02136	COG0511	ligase activity, forming carbon-carbon bonds
ACICU_02139	COG2814	Major facilitator Superfamily
ACICU_02161	COG0592	DNA-directed DNA polymerase activity
ACICU_02169	COG2026	Addiction module toxin, RelE StbE family
ACICU_02208	COG1484	DNA-dependent DNA replication
ACICU_02225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACICU_02239	COG0069	glutamate synthase activity
ACICU_02243	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACICU_02245	COG1454	alcohol dehydrogenase
ACICU_02246	COG0824	Thioesterase
ACICU_02248	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACICU_02254	COG0183	Belongs to the thiolase family
ACICU_02256	COG0583	DNA-binding transcription factor activity
ACICU_02259	COG1522	sequence-specific DNA binding
ACICU_02260	COG3135	benzoate transporter
ACICU_02262	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACICU_02267	COG0589	response to stress
ACICU_02268	COG0488	(ABC) transporter
ACICU_02272	COG4773	Receptor
ACICU_02278	COG0668	transmembrane transport
ACICU_02280	COG1309	transcriptional regulator
ACICU_02284	COG1605	Chorismate mutase
ACICU_02286	COG4221	oxidoreductase activity
ACICU_02288	COG0308	aminopeptidase N
ACICU_02292	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ACICU_02294	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACICU_02295	COG1454	alcohol dehydrogenase
ACICU_02299	COG0531	amino acid
ACICU_02300	COG4303	Ethanolamine ammonia lyase large subunit
ACICU_02301	COG4302	ethanolamine ammonia-lyase activity
ACICU_02302	COG0519	Catalyzes the synthesis of GMP from XMP
ACICU_02302	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACICU_02306	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACICU_02309	COG0697	spore germination
ACICU_02310	COG1923	regulation of RNA biosynthetic process
ACICU_02312	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACICU_02313	COG0802	atpase or kinase
ACICU_02317	COG1187	pseudouridine synthase activity
ACICU_02322	COG0583	DNA-binding transcription factor activity
ACICU_02325	COG2814	Major facilitator Superfamily
ACICU_02326	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACICU_02332	COG0729	surface antigen
ACICU_02336	COG0174	glutamine synthetase
ACICU_02337	COG0745	RESPONSE REGULATOR receiver
ACICU_02338	COG2205	protein histidine kinase activity
ACICU_02340	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACICU_02341	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACICU_02346	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_02347	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACICU_02348	COG1960	acyl-CoA dehydrogenase activity
ACICU_02351	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACICU_02352	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACICU_02356	COG0583	DNA-binding transcription factor activity
ACICU_02359	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACICU_02361	COG3658	cytochrome
ACICU_02362	COG1215	transferase activity, transferring glycosyl groups
ACICU_02363	COG1649	PFAM Uncharacterised BCR, COG1649
ACICU_02363	COG0726	polysaccharide deacetylase
ACICU_02369	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACICU_02370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACICU_02372	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACICU_02377	COG0305	Participates in initiation and elongation during chromosome replication
ACICU_02378	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACICU_02380	COG1305	Transglutaminase-like
ACICU_02382	COG2308	Evidence 4 Homologs of previously reported genes of
ACICU_02388	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACICU_02389	COG0138	bifunctional purine biosynthesis protein purh
ACICU_02390	COG0151	Belongs to the GarS family
ACICU_02391	COG1464	Belongs to the NlpA lipoprotein family
ACICU_02392	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACICU_02393	COG2011	ABC-type metal ion transport system permease component
ACICU_02394	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_02396	COG1301	dicarboxylic acid transport
ACICU_02402	COG1794	racemase activity, acting on amino acids and derivatives
ACICU_02404	COG3008	intermembrane lipid transfer
ACICU_02404	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACICU_02405	COG2995	paraquat-inducible protein a
ACICU_02406	COG2985	domain, Protein
ACICU_02411	COG0477	Major facilitator Superfamily
ACICU_02412	COG0477	Major facilitator Superfamily
ACICU_02419	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_02423	COG2186	Transcriptional regulator
ACICU_02425	COG0786	glutamate:sodium symporter activity
ACICU_02426	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACICU_02431	COG3111	PFAM Bacterial OB fold (BOF) protein
ACICU_02446	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACICU_02447	COG1610	YqeY-like protein
ACICU_02448	COG4783	chaperone-mediated protein folding
ACICU_02453	COG1286	toxin biosynthetic process
ACICU_02459	COG0778	Nitroreductase
ACICU_02461	COG0513	Belongs to the DEAD box helicase family
ACICU_02465	COG2363	Small membrane protein
ACICU_02471	COG1234	tRNA 3'-trailer cleavage
ACICU_02472	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACICU_02474	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACICU_02476	COG2819	hydrolase of the alpha beta superfamily
ACICU_02477	COG1960	acyl-CoA dehydrogenase activity
ACICU_02478	COG1301	dicarboxylic acid transport
ACICU_02479	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACICU_02480	COG3139	Protein of unknown function (DUF1315)
ACICU_02481	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACICU_02482	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACICU_02484	COG0494	nUDIX hydrolase
ACICU_02486	COG0642	Histidine kinase
ACICU_02487	COG0745	RESPONSE REGULATOR receiver
ACICU_02491	COG1720	tRNA m6t6A37 methyltransferase activity
ACICU_02494	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACICU_02496	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACICU_02498	COG4598	ABC transporter
ACICU_02499	COG4160	amino acid transport
ACICU_02500	COG4215	(ABC) transporter
ACICU_02504	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_02506	COG1538	Outer membrane efflux protein
ACICU_02512	COG1131	(ABC) transporter
ACICU_02513	COG0842	Transport permease protein
ACICU_02516	COG0772	Belongs to the SEDS family
ACICU_02517	COG2951	lytic endotransglycosylase activity
ACICU_02522	COG2207	Transcriptional regulator
ACICU_02525	COG0052	Belongs to the universal ribosomal protein uS2 family
ACICU_02526	COG0024	Methionine aminopeptidase
ACICU_02528	COG2223	nitrite transmembrane transporter activity
ACICU_02531	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACICU_02532	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACICU_02533	COG1960	acyl-CoA dehydrogenase activity
ACICU_02536	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACICU_02537	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACICU_02538	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACICU_02542	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACICU_02543	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACICU_02544	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACICU_02548	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACICU_02551	COG3104	oligopeptide transport
ACICU_02553	COG0512	Glutamine amidotransferase of anthranilate synthase
ACICU_02554	COG0308	aminopeptidase N
ACICU_02560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACICU_02563	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_02567	COG3739	integral membrane protein
ACICU_02570	COG1169	isochorismate synthase
ACICU_02572	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACICU_02574	COG1132	(ABC) transporter
ACICU_02577	COG1535	isochorismatase
ACICU_02577	COG3433	isochorismatase activity
ACICU_02578	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACICU_02579	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACICU_02581	COG4774	siderophore transport
ACICU_02582	COG4607	ABC-type enterochelin transport system periplasmic component
ACICU_02583	COG4604	ABC transporter, ATP-binding protein
ACICU_02584	COG4605	iron ion homeostasis
ACICU_02585	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACICU_02587	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACICU_02590	COG2964	Protein conserved in bacteria
ACICU_02594	COG1741	Belongs to the pirin family
ACICU_02597	COG1309	transcriptional regulator
ACICU_02599	COG4948	Mandelate Racemase Muconate Lactonizing
ACICU_02600	COG2814	Major facilitator Superfamily
ACICU_02607	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACICU_02607	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ACICU_02608	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_02611	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_02612	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_02613	COG0583	DNA-binding transcription factor activity
ACICU_02614	COG1113	amino acid transport
ACICU_02618	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ACICU_02618	COG2508	Transcriptional regulator
ACICU_02624	COG2879	small protein
ACICU_02625	COG1966	Carbon starvation protein
ACICU_02636	COG1067	ATP-dependent peptidase activity
ACICU_02637	COG0583	DNA-binding transcription factor activity
ACICU_02642	COG1686	Belongs to the peptidase S11 family
ACICU_02643	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACICU_02650	COG0616	signal peptide processing
ACICU_02651	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACICU_02653	COG0573	inorganic phosphate transmembrane transporter activity
ACICU_02654	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACICU_02655	COG1113	amino acid transport
ACICU_02656	COG3961	Belongs to the TPP enzyme family
ACICU_02657	COG1522	sequence-specific DNA binding
ACICU_02659	COG0076	glutamate decarboxylase activity
ACICU_02660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACICU_02662	COG1309	transcriptional regulator
ACICU_02665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACICU_02673	COG0352	thiamine-phosphate diphosphorylase activity
ACICU_02679	COG0612	Peptidase, M16
ACICU_02682	COG0583	DNA-binding transcription factor activity
ACICU_02683	COG0477	Major facilitator Superfamily
ACICU_02688	COG1187	pseudouridine synthase activity
ACICU_02691	COG1686	Belongs to the peptidase S11 family
ACICU_02692	COG1252	NADH dehydrogenase
ACICU_02694	COG0415	Belongs to the DNA photolyase family
ACICU_02697	COG1215	transferase activity, transferring glycosyl groups
ACICU_02703	COG2070	2-Nitropropane dioxygenase
ACICU_02743	COG5410	chromosome segregation
ACICU_02782	COG0556	nucleotide-excision repair
ACICU_02790	COG4221	oxidoreductase activity
ACICU_02792	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACICU_02793	COG1381	Involved in DNA repair and RecF pathway recombination
ACICU_02795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACICU_02798	COG0681	Belongs to the peptidase S26 family
ACICU_02801	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACICU_02805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACICU_02806	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACICU_02807	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACICU_02809	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACICU_02810	COG4208	sulfate ABC transporter
ACICU_02811	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACICU_02812	COG0583	DNA-binding transcription factor activity
ACICU_02813	COG4625	pathogenesis
ACICU_02816	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACICU_02819	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACICU_02821	COG1051	belongs to the nudix hydrolase family
ACICU_02821	COG1056	cytidyltransferase-related domain
ACICU_02822	COG1024	Enoyl-CoA hydratase
ACICU_02823	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACICU_02826	COG2814	Major facilitator Superfamily
ACICU_02827	COG0047	phosphoribosylformylglycinamidine synthase activity
ACICU_02827	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACICU_02831	COG1473	amidohydrolase
ACICU_02832	COG0824	Thioesterase
ACICU_02836	COG0823	Involved in the tonB-independent uptake of proteins
ACICU_02840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACICU_02848	COG0628	permease
ACICU_02850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACICU_02851	COG0596	Alpha beta hydrolase
ACICU_02852	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACICU_02852	COG0616	signal peptide processing
ACICU_02854	COG0658	competence protein
ACICU_02854	COG2333	competence protein COMEC
ACICU_02855	COG1136	(ABC) transporter
ACICU_02856	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACICU_02862	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_02866	COG0463	Glycosyl transferase, family 2
ACICU_02872	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACICU_02875	COG0019	diaminopimelate decarboxylase activity
ACICU_02877	COG1113	amino acid transport
ACICU_02880	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACICU_02882	COG3339	Conserved Protein
ACICU_02884	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACICU_02885	COG0243	molybdopterin cofactor binding
ACICU_02886	COG1929	Belongs to the glycerate kinase type-1 family
ACICU_02889	COG0778	Nitroreductase
ACICU_02895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACICU_02897	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACICU_02901	COG0741	lytic transglycosylase activity
ACICU_02905	COG0584	glycerophosphoryl diester phosphodiesterase
ACICU_02906	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_02911	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACICU_02915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACICU_02916	COG0477	Major facilitator Superfamily
ACICU_02923	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACICU_02924	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACICU_02929	COG0505	Belongs to the CarA family
ACICU_02933	COG0589	response to stress
ACICU_02936	COG2843	Capsule synthesis protein
ACICU_02948	COG2321	neutral zinc metallopeptidase
ACICU_02949	COG2354	Protein conserved in bacteria
ACICU_02953	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACICU_02957	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACICU_02958	COG1053	succinate dehydrogenase
ACICU_02959	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACICU_02960	COG2009	succinate dehydrogenase
ACICU_02965	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_02970	COG2921	Belongs to the UPF0250 family
ACICU_02971	COG0321	lipoyl(octanoyl) transferase activity
ACICU_02974	COG0531	amino acid
ACICU_02976	COG1733	regulation of RNA biosynthetic process
ACICU_02977	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACICU_02978	COG1648	precorrin-2 dehydrogenase activity
ACICU_02978	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACICU_02981	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACICU_02986	COG0671	phosphoesterase, PA-phosphatase related
ACICU_02987	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_02989	COG1538	Outer membrane efflux protein
ACICU_02990	COG0393	Putative heavy-metal-binding
ACICU_02991	COG0393	Putative heavy-metal-binding
ACICU_02993	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_02995	COG0525	valine-tRNA ligase activity
ACICU_02999	COG0583	DNA-binding transcription factor activity
ACICU_03000	COG0004	ammonium transporteR
ACICU_03002	COG0642	Histidine kinase
ACICU_03003	COG0745	RESPONSE REGULATOR receiver
ACICU_03004	COG2194	sulfuric ester hydrolase activity
ACICU_03008	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACICU_03011	COG2315	Protein conserved in bacteria
ACICU_03012	COG0142	geranyltranstransferase activity
ACICU_03013	COG2828	Protein conserved in bacteria
ACICU_03014	COG1113	amino acid transport
ACICU_03017	COG2207	Transcriptional regulator
ACICU_03022	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACICU_03026	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACICU_03028	COG1530	ribonuclease E activity
ACICU_03029	COG0424	maF-like protein
ACICU_03030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACICU_03031	COG1792	Involved in formation and maintenance of cell shape
ACICU_03032	COG1077	Cell shape determining protein MreB Mrl
ACICU_03033	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACICU_03035	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACICU_03041	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ACICU_03042	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACICU_03043	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACICU_03044	COG1115	amino acid carrier protein
ACICU_03048	COG2814	Major facilitator Superfamily
ACICU_03049	COG1289	transmembrane transporter activity
ACICU_03053	COG1376	ErfK ybiS ycfS ynhG family protein
ACICU_03054	COG2832	Protein of unknown function (DUF454)
ACICU_03056	COG5510	response to toxic substance
ACICU_03060	COG0840	transmembrane signaling receptor activity
ACICU_03068	COG3422	double-strand break repair
ACICU_03069	COG2824	Alkylphosphonate utilization operon protein PhnA
ACICU_03070	COG3189	MarR family transcriptional regulator
ACICU_03072	COG0354	folic acid binding
ACICU_03073	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACICU_03075	COG0679	Auxin Efflux Carrier
ACICU_03076	COG1902	pentaerythritol trinitrate reductase activity
ACICU_03077	COG4772	TonB-dependent receptor
ACICU_03078	COG2094	Belongs to the DNA glycosylase MPG family
ACICU_03084	COG2233	PERMEase
ACICU_03086	COG0833	amino acid
ACICU_03087	COG1690	Belongs to the RtcB family
ACICU_03089	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACICU_03089	COG2885	chlorophyll binding
ACICU_03091	COG0183	Belongs to the thiolase family
ACICU_03095	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_03099	COG2207	Transcriptional regulator
ACICU_03100	COG0183	Belongs to the thiolase family
ACICU_03107	COG1272	protein, Hemolysin III
ACICU_03108	COG0477	Major facilitator Superfamily
ACICU_03111	COG0450	alkyl hydroperoxide reductase
ACICU_03115	COG0285	dihydrofolate synthase activity
ACICU_03122	COG0133	tryptophan synthase activity
ACICU_03125	COG2096	Adenosyltransferase
ACICU_03129	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACICU_03130	COG0745	RESPONSE REGULATOR receiver
ACICU_03131	COG2205	protein histidine kinase activity
ACICU_03133	COG1960	acyl-CoA dehydrogenase activity
ACICU_03134	COG1960	acyl-CoA dehydrogenase activity
ACICU_03136	COG0583	DNA-binding transcription factor activity
ACICU_03137	COG0625	glutathione transferase activity
ACICU_03150	COG0438	transferase activity, transferring glycosyl groups
ACICU_03151	COG0463	Glycosyl transferase, family 2
ACICU_03152	COG0726	polysaccharide deacetylase
ACICU_03156	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACICU_03157	COG2205	protein histidine kinase activity
ACICU_03165	COG1862	Preprotein translocase
ACICU_03167	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACICU_03168	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACICU_03170	COG3781	membrane
ACICU_03171	COG0613	PHP domain protein
ACICU_03173	COG2350	Protein conserved in bacteria
ACICU_03180	COG1607	acyl-coa hydrolase
ACICU_03183	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_03183	COG3453	Protein conserved in bacteria
ACICU_03187	COG2199	diguanylate cyclase activity
ACICU_03189	COG1408	metallophosphoesterase
ACICU_03190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACICU_03192	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACICU_03196	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACICU_03197	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACICU_03200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACICU_03202	COG2969	positive regulation of protein catabolic process
ACICU_03206	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_03208	COG1960	acyl-CoA dehydrogenase activity
ACICU_03209	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACICU_03212	COG1309	transcriptional regulator
ACICU_03213	COG1960	acyl-CoA dehydrogenase activity
ACICU_03217	COG1183	phosphatidylcholine synthase activity
ACICU_03218	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACICU_03224	COG0739	heme binding
ACICU_03224	COG0741	lytic transglycosylase activity
ACICU_03224	COG1196	nuclear chromosome segregation
ACICU_03226	COG1702	phosphate starvation-inducible protein PhoH
ACICU_03233	COG1295	ribonuclease BN
ACICU_03234	COG0697	spore germination
ACICU_03235	COG2169	Transcriptional regulator
ACICU_03236	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACICU_03241	COG0557	exoribonuclease II activity
ACICU_03242	COG0339	signal peptide processing
ACICU_03243	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ACICU_03249	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACICU_03250	COG1960	acyl-CoA dehydrogenase activity
ACICU_03255	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACICU_03257	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACICU_03283	COG0626	cystathionine gamma-synthase activity
ACICU_03284	COG0433	COG0433 Predicted ATPase
ACICU_03285	COG1017	nitric oxide dioxygenase activity
ACICU_03285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACICU_03286	COG1959	2 iron, 2 sulfur cluster binding
ACICU_03289	COG1301	dicarboxylic acid transport
ACICU_03290	COG1946	Acyl-CoA thioesterase
ACICU_03294	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACICU_03295	COG1040	competence protein
ACICU_03296	COG0494	nUDIX hydrolase
ACICU_03298	COG0598	Magnesium transport protein CorA
ACICU_03300	COG2854	intermembrane phospholipid transfer
ACICU_03302	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACICU_03303	COG1127	ABC transporter
ACICU_03305	COG0513	Belongs to the DEAD box helicase family
ACICU_03309	COG0408	coproporphyrinogen oxidase activity
ACICU_03312	COG1960	acyl-CoA dehydrogenase activity
ACICU_03314	COG1983	PspC domain protein
ACICU_03315	COG0517	IMP dehydrogenase activity
ACICU_03324	COG0583	DNA-binding transcription factor activity
ACICU_03332	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_03334	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACICU_03335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACICU_03336	COG0833	amino acid
ACICU_03343	COG0628	permease
ACICU_03345	COG1289	transmembrane transporter activity
ACICU_03348	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACICU_03349	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACICU_03351	COG0277	FAD linked oxidase domain protein
ACICU_03352	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACICU_03357	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACICU_03358	COG5380	lipid catabolic process
ACICU_03362	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACICU_03372	COG0194	GDP metabolic process
ACICU_03374	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACICU_03378	COG3307	-O-antigen
ACICU_03382	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACICU_03383	COG1704	LemA family
ACICU_03385	COG0493	'glutamate synthase
ACICU_03386	COG0069	glutamate synthase activity
ACICU_03386	COG0067	glutamate synthase
ACICU_03386	COG0070	glutamate synthase
ACICU_03396	COG2226	methyltransferase
ACICU_03399	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACICU_03400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACICU_03407	COG0833	amino acid
ACICU_03419	COG0488	(ABC) transporter
ACICU_03421	COG4221	oxidoreductase activity
ACICU_03422	COG0659	secondary active sulfate transmembrane transporter activity
ACICU_03424	COG0745	RESPONSE REGULATOR receiver
ACICU_03426	COG0427	acetyl-CoA hydrolase
ACICU_03431	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACICU_03439	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACICU_03449	COG2207	Transcriptional regulator
ACICU_03450	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACICU_03453	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACICU_03454	COG1733	regulation of RNA biosynthetic process
ACICU_03458	COG1733	regulation of RNA biosynthetic process
ACICU_03463	COG0667	Aldo Keto reductase
ACICU_03468	COG0583	DNA-binding transcription factor activity
ACICU_03469	COG2814	Major facilitator Superfamily
ACICU_03474	COG1335	isochorismatase
ACICU_03476	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_03477	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACICU_03479	COG1113	amino acid transport
ACICU_03481	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACICU_03484	COG2814	Major facilitator Superfamily
ACICU_03486	COG0352	thiamine-phosphate diphosphorylase activity
ACICU_03486	COG0351	phosphomethylpyrimidine kinase
ACICU_03486	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACICU_03490	COG1309	transcriptional regulator
ACICU_03491	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACICU_03492	COG3706	GGDEF domain
ACICU_03494	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_03496	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACICU_03497	COG3162	membrane
ACICU_03498	COG0784	Response regulator, receiver
ACICU_03498	COG2205	protein histidine kinase activity
ACICU_03498	COG2198	Histidine kinase
ACICU_03503	COG1522	sequence-specific DNA binding
ACICU_03504	COG1335	isochorismatase
ACICU_03505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACICU_03507	COG0668	transmembrane transport
ACICU_03508	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACICU_03509	COG1519	Transferase
ACICU_03510	COG1902	pentaerythritol trinitrate reductase activity
ACICU_03515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACICU_03520	COG0426	domain, Protein
ACICU_03520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_03521	COG4774	siderophore transport
ACICU_03522	COG2119	membrane
ACICU_03524	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACICU_03526	COG4942	peptidase
ACICU_03529	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACICU_03531	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACICU_03535	COG0189	ligase activity
ACICU_03539	COG0708	Exodeoxyribonuclease III
ACICU_03540	COG1393	Belongs to the ArsC family
ACICU_03543	COG3706	GGDEF domain
ACICU_03551	COG2233	PERMEase
ACICU_03553	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_03555	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ACICU_03557	COG3150	esterase
ACICU_03562	COG3179	chitinase
ACICU_03563	COG3501	Rhs element vgr protein
ACICU_03565	COG2918	glutathione biosynthetic process
ACICU_03568	COG2733	membrane
ACICU_03569	COG0436	Aminotransferase
ACICU_03570	COG0534	Mate efflux family protein
ACICU_03582	COG0753	catalase activity
ACICU_03591	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACICU_03592	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACICU_03594	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACICU_03595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACICU_03596	COG0546	phosphoglycolate phosphatase activity
ACICU_03598	COG0010	Belongs to the arginase family
ACICU_03604	COG2188	Transcriptional regulator
ACICU_03606	COG0523	cobalamin synthesis protein
ACICU_03609	COG1113	amino acid transport
ACICU_03611	COG0625	glutathione transferase activity
ACICU_03615	COG1683	Conserved Protein
ACICU_03616	COG0534	Mate efflux family protein
ACICU_03617	COG0385	Bile acid
ACICU_03618	COG1335	isochorismatase
ACICU_03619	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACICU_03623	COG2116	formate transmembrane transporter activity
ACICU_03624	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACICU_03625	COG2133	pyrroloquinoline quinone binding
ACICU_03626	COG2983	Belongs to the UPF0260 family
ACICU_03630	COG1194	a g-specific adenine glycosylase
ACICU_03633	COG2818	Glycosylase
ACICU_03634	COG1064	alcohol dehydrogenase
ACICU_03635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACICU_03638	COG0583	DNA-binding transcription factor activity
ACICU_03639	COG0656	L-ascorbic acid biosynthetic process
ACICU_03640	COG2814	Major facilitator Superfamily
ACICU_03647	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_03650	COG2233	PERMEase
ACICU_03658	COG0733	neurotransmitter:sodium symporter activity
ACICU_03662	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACICU_03663	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACICU_03664	COG0596	Alpha beta hydrolase
ACICU_03669	COG0488	(ABC) transporter
ACICU_03670	COG0586	Pfam SNARE associated Golgi protein
ACICU_p0003	COG3316	Transposase and inactivated derivatives
ACICU_p0004	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACICU_p0006	COG1192	Involved in chromosome partitioning
ACICU_p0010	COG2026	Addiction module toxin, RelE StbE family
ACICU_p0014	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACICU_p0022	COG3316	Transposase and inactivated derivatives
ACICU_p0027	COG3316	Transposase and inactivated derivatives
ACICU_p0040	COG1525	nuclease
ACICU_p0048	COG1475	DNA binding
ACICU_p0050	COG3853	Toxic anion resistance protein (TelA)
ACICU_p0055	COG0484	heat shock protein binding
ACICU_p0065	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_p0070	COG0741	lytic transglycosylase activity
ACICU_p0076	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACICU_p0091	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII