locus-tag	class	description
CSB68_0013	COG0339	signal peptide processing
CSB68_0014	COG0557	exoribonuclease II activity
CSB68_0023	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSB68_0024	COG2169	Transcriptional regulator
CSB68_0025	COG0697	spore germination
CSB68_0026	COG1295	ribonuclease BN
CSB68_0033	COG1702	phosphate starvation-inducible protein PhoH
CSB68_0035	COG1196	nuclear chromosome segregation
CSB68_0035	COG0739	heme binding
CSB68_0035	COG0741	lytic transglycosylase activity
CSB68_0041	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CSB68_0042	COG1183	phosphatidylcholine synthase activity
CSB68_0051	COG1960	acyl-CoA dehydrogenase activity
CSB68_0052	COG1309	transcriptional regulator
CSB68_0056	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSB68_0057	COG1960	acyl-CoA dehydrogenase activity
CSB68_0065	COG2969	positive regulation of protein catabolic process
CSB68_0067	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CSB68_0069	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CSB68_0070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CSB68_0071	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CSB68_0075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSB68_0077	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSB68_0078	COG1408	metallophosphoesterase
CSB68_0080	COG2199	diguanylate cyclase activity
CSB68_0089	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB68_0089	COG3453	Protein conserved in bacteria
CSB68_0092	COG1607	acyl-coa hydrolase
CSB68_0098	COG2350	Protein conserved in bacteria
CSB68_0100	COG0613	PHP domain protein
CSB68_0101	COG3781	membrane
CSB68_0103	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSB68_0104	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSB68_0106	COG1862	Preprotein translocase
CSB68_0115	COG2205	protein histidine kinase activity
CSB68_0116	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CSB68_0119	COG0726	polysaccharide deacetylase
CSB68_0123	COG1091	dTDP-4-dehydrorhamnose reductase activity
CSB68_0126	COG1215	transferase activity, transferring glycosyl groups
CSB68_0138	COG1960	acyl-CoA dehydrogenase activity
CSB68_0139	COG1960	acyl-CoA dehydrogenase activity
CSB68_0141	COG2205	protein histidine kinase activity
CSB68_0142	COG0745	RESPONSE REGULATOR receiver
CSB68_0143	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CSB68_0146	COG0584	glycerophosphoryl diester phosphodiesterase
CSB68_0147	COG2096	Adenosyltransferase
CSB68_0150	COG0133	tryptophan synthase activity
CSB68_0157	COG0285	dihydrofolate synthase activity
CSB68_0161	COG0450	alkyl hydroperoxide reductase
CSB68_0164	COG0477	Major facilitator Superfamily
CSB68_0165	COG1272	protein, Hemolysin III
CSB68_0167	COG2153	protein acetylation
CSB68_0171	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB68_0171	COG1024	Enoyl-CoA hydratase
CSB68_0172	COG0183	Belongs to the thiolase family
CSB68_0173	COG2207	Transcriptional regulator
CSB68_0178	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB68_0182	COG0183	Belongs to the thiolase family
CSB68_0184	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CSB68_0184	COG2885	chlorophyll binding
CSB68_0186	COG1690	Belongs to the RtcB family
CSB68_0187	COG0833	amino acid
CSB68_0189	COG2233	PERMEase
CSB68_0195	COG2094	Belongs to the DNA glycosylase MPG family
CSB68_0196	COG4772	TonB-dependent receptor
CSB68_0197	COG1902	pentaerythritol trinitrate reductase activity
CSB68_0200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB68_0201	COG0354	folic acid binding
CSB68_0203	COG3189	MarR family transcriptional regulator
CSB68_0204	COG2824	Alkylphosphonate utilization operon protein PhnA
CSB68_0205	COG3422	double-strand break repair
CSB68_0213	COG0840	transmembrane signaling receptor activity
CSB68_0216	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSB68_0219	COG5510	response to toxic substance
CSB68_0221	COG2832	Protein of unknown function (DUF454)
CSB68_0222	COG1376	ErfK ybiS ycfS ynhG family protein
CSB68_0232	COG1289	transmembrane transporter activity
CSB68_0233	COG2814	Major facilitator Superfamily
CSB68_0238	COG1115	amino acid carrier protein
CSB68_0239	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSB68_0240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSB68_0241	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CSB68_0242	COG3590	peptidase
CSB68_0247	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB68_0249	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB68_0250	COG1077	Cell shape determining protein MreB Mrl
CSB68_0251	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB68_0252	COG1077	Cell shape determining protein MreB Mrl
CSB68_0253	COG1792	Involved in formation and maintenance of cell shape
CSB68_0255	COG0424	maF-like protein
CSB68_0256	COG1530	ribonuclease E activity
CSB68_0258	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB68_0262	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB68_0267	COG2207	Transcriptional regulator
CSB68_0271	COG1113	amino acid transport
CSB68_0273	COG2828	Protein conserved in bacteria
CSB68_0274	COG0142	geranyltranstransferase activity
CSB68_0275	COG2315	Protein conserved in bacteria
CSB68_0278	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSB68_0282	COG2194	sulfuric ester hydrolase activity
CSB68_0283	COG0745	RESPONSE REGULATOR receiver
CSB68_0284	COG0642	Histidine kinase
CSB68_0286	COG0004	ammonium transporteR
CSB68_0287	COG0583	DNA-binding transcription factor activity
CSB68_0290	COG2226	methyltransferase
CSB68_0291	COG0525	valine-tRNA ligase activity
CSB68_0293	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_0295	COG0393	Putative heavy-metal-binding
CSB68_0296	COG0393	Putative heavy-metal-binding
CSB68_0297	COG1538	Outer membrane efflux protein
CSB68_0299	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB68_0300	COG0671	phosphoesterase, PA-phosphatase related
CSB68_0306	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CSB68_0309	COG1648	precorrin-2 dehydrogenase activity
CSB68_0309	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CSB68_0310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CSB68_0311	COG1733	regulation of RNA biosynthetic process
CSB68_0313	COG0531	amino acid
CSB68_0316	COG0321	lipoyl(octanoyl) transferase activity
CSB68_0317	COG2921	Belongs to the UPF0250 family
CSB68_0325	COG2009	succinate dehydrogenase
CSB68_0326	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CSB68_0327	COG1053	succinate dehydrogenase
CSB68_0328	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSB68_0332	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB68_0336	COG2354	Protein conserved in bacteria
CSB68_0337	COG2321	neutral zinc metallopeptidase
CSB68_0342	COG2843	Capsule synthesis protein
CSB68_0345	COG0589	response to stress
CSB68_0347	COG0251	oxidation-reduction process
CSB68_0348	COG1309	transcriptional regulator
CSB68_0351	COG0505	Belongs to the CarA family
CSB68_0356	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSB68_0357	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSB68_0367	COG0477	Major facilitator Superfamily
CSB68_0368	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CSB68_0372	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSB68_0407	COG5410	chromosome segregation
CSB68_0429	COG0739	heme binding
CSB68_0429	COG1196	nuclear chromosome segregation
CSB68_0429	COG0741	lytic transglycosylase activity
CSB68_0436	COG3179	chitinase
CSB68_0438	COG1063	alcohol dehydrogenase
CSB68_0439	COG3293	Transposase
CSB68_0442	COG0582	viral genome integration into host DNA
CSB68_0444	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB68_0445	COG0584	glycerophosphoryl diester phosphodiesterase
CSB68_0449	COG0741	lytic transglycosylase activity
CSB68_0455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSB68_0459	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB68_0463	COG0789	Transcriptional regulator
CSB68_0469	COG0778	Nitroreductase
CSB68_0472	COG1929	Belongs to the glycerate kinase type-1 family
CSB68_0473	COG0243	molybdopterin cofactor binding
CSB68_0474	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSB68_0475	COG3339	Conserved Protein
CSB68_0480	COG1115	amino acid carrier protein
CSB68_0482	COG1113	amino acid transport
CSB68_0484	COG0019	diaminopimelate decarboxylase activity
CSB68_0486	COG2267	carboxylic ester hydrolase activity
CSB68_0487	COG1280	lysine exporter protein (LysE YggA)
CSB68_0488	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSB68_0494	COG0463	Glycosyl transferase, family 2
CSB68_0498	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB68_0504	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSB68_0505	COG1136	(ABC) transporter
CSB68_0506	COG2333	competence protein COMEC
CSB68_0506	COG0658	competence protein
CSB68_0508	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSB68_0508	COG0616	signal peptide processing
CSB68_0509	COG0596	Alpha beta hydrolase
CSB68_0510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSB68_0512	COG0628	permease
CSB68_0521	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSB68_0525	COG0823	Involved in the tonB-independent uptake of proteins
CSB68_0529	COG0824	Thioesterase
CSB68_0530	COG1473	amidohydrolase
CSB68_0534	COG0047	phosphoribosylformylglycinamidine synthase activity
CSB68_0534	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSB68_0535	COG2814	Major facilitator Superfamily
CSB68_0537	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSB68_0538	COG1024	Enoyl-CoA hydratase
CSB68_0539	COG1056	cytidyltransferase-related domain
CSB68_0539	COG1051	belongs to the nudix hydrolase family
CSB68_0541	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSB68_0544	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CSB68_0547	COG4625	pathogenesis
CSB68_0548	COG0583	DNA-binding transcription factor activity
CSB68_0549	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CSB68_0550	COG4208	sulfate ABC transporter
CSB68_0551	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CSB68_0554	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CSB68_0555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSB68_0556	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CSB68_0560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSB68_0563	COG0681	Belongs to the peptidase S26 family
CSB68_0566	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSB68_0568	COG1381	Involved in DNA repair and RecF pathway recombination
CSB68_0569	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CSB68_0571	COG4221	oxidoreductase activity
CSB68_0576	COG0443	Heat shock 70 kDa protein
CSB68_0584	COG0556	nucleotide-excision repair
CSB68_0596	COG2070	2-Nitropropane dioxygenase
CSB68_0602	COG1215	transferase activity, transferring glycosyl groups
CSB68_0605	COG0415	Belongs to the DNA photolyase family
CSB68_0607	COG1252	NADH dehydrogenase
CSB68_0608	COG1686	Belongs to the peptidase S11 family
CSB68_0611	COG1187	pseudouridine synthase activity
CSB68_0617	COG0583	DNA-binding transcription factor activity
CSB68_0620	COG0612	Peptidase, M16
CSB68_0625	COG0352	thiamine-phosphate diphosphorylase activity
CSB68_0632	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB68_0634	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB68_0637	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSB68_0638	COG0076	glutamate decarboxylase activity
CSB68_0640	COG1522	sequence-specific DNA binding
CSB68_0641	COG3961	Belongs to the TPP enzyme family
CSB68_0642	COG1113	amino acid transport
CSB68_0643	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSB68_0644	COG0573	inorganic phosphate transmembrane transporter activity
CSB68_0646	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSB68_0647	COG0616	signal peptide processing
CSB68_0649	COG4372	Transposase
CSB68_0658	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSB68_0659	COG1686	Belongs to the peptidase S11 family
CSB68_0664	COG0583	DNA-binding transcription factor activity
CSB68_0665	COG1067	ATP-dependent peptidase activity
CSB68_0671	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CSB68_0675	COG1966	Carbon starvation protein
CSB68_0676	COG2879	small protein
CSB68_0683	COG1741	Belongs to the pirin family
CSB68_0685	COG2964	Protein conserved in bacteria
CSB68_0688	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB68_0690	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSB68_0691	COG4605	iron ion homeostasis
CSB68_0692	COG4604	ABC transporter, ATP-binding protein
CSB68_0693	COG4607	ABC-type enterochelin transport system periplasmic component
CSB68_0694	COG4774	siderophore transport
CSB68_0696	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB68_0697	COG1021	2,3-dihydroxybenzoate-AMP ligase
CSB68_0698	COG1535	isochorismatase
CSB68_0698	COG3433	isochorismatase activity
CSB68_0701	COG1132	(ABC) transporter
CSB68_0703	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CSB68_0708	COG3739	integral membrane protein
CSB68_0718	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CSB68_0725	COG0512	Glutamine amidotransferase of anthranilate synthase
CSB68_0727	COG3104	oligopeptide transport
CSB68_0730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CSB68_0737	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSB68_0738	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSB68_0739	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSB68_0743	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSB68_0744	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSB68_0745	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CSB68_0748	COG1960	acyl-CoA dehydrogenase activity
CSB68_0749	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CSB68_0750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB68_0753	COG2223	nitrite transmembrane transporter activity
CSB68_0756	COG0024	Methionine aminopeptidase
CSB68_0757	COG0052	Belongs to the universal ribosomal protein uS2 family
CSB68_0760	COG2207	Transcriptional regulator
CSB68_0764	COG2951	lytic endotransglycosylase activity
CSB68_0765	COG0772	Belongs to the SEDS family
CSB68_0768	COG0842	Transport permease protein
CSB68_0769	COG1131	(ABC) transporter
CSB68_0770	COG0582	viral genome integration into host DNA
CSB68_0776	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB68_0791	COG0305	Participates in initiation and elongation during chromosome replication
CSB68_0842	COG1538	Outer membrane efflux protein
CSB68_0844	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB68_0847	COG4215	(ABC) transporter
CSB68_0848	COG4160	amino acid transport
CSB68_0849	COG4598	ABC transporter
CSB68_0851	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSB68_0853	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB68_0856	COG1720	tRNA m6t6A37 methyltransferase activity
CSB68_0860	COG0745	RESPONSE REGULATOR receiver
CSB68_0861	COG0642	Histidine kinase
CSB68_0863	COG0494	nUDIX hydrolase
CSB68_0865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSB68_0866	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CSB68_0867	COG3139	Protein of unknown function (DUF1315)
CSB68_0868	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSB68_0869	COG1301	dicarboxylic acid transport
CSB68_0870	COG1960	acyl-CoA dehydrogenase activity
CSB68_0871	COG2819	hydrolase of the alpha beta superfamily
CSB68_0873	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CSB68_0875	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSB68_0876	COG1234	tRNA 3'-trailer cleavage
CSB68_0882	COG2363	Small membrane protein
CSB68_0886	COG0513	Belongs to the DEAD box helicase family
CSB68_0888	COG0778	Nitroreductase
CSB68_0894	COG1286	toxin biosynthetic process
CSB68_0899	COG4783	chaperone-mediated protein folding
CSB68_0900	COG1610	YqeY-like protein
CSB68_0901	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CSB68_0906	COG0515	serine threonine protein kinase
CSB68_0906	COG2815	serine threonine protein kinase
CSB68_0911	COG2831	hemolysin activation secretion protein
CSB68_0912	COG3210	domain, Protein
CSB68_0915	COG3328	transposase activity
CSB68_0926	COG3111	PFAM Bacterial OB fold (BOF) protein
CSB68_0931	COG3243	poly(R)-hydroxyalkanoic acid synthase
CSB68_0932	COG0786	glutamate:sodium symporter activity
CSB68_0934	COG2186	Transcriptional regulator
CSB68_0944	COG0477	Major facilitator Superfamily
CSB68_0945	COG1051	belongs to the nudix hydrolase family
CSB68_0951	COG2985	domain, Protein
CSB68_0954	COG2995	paraquat-inducible protein a
CSB68_0955	COG3008	intermembrane lipid transfer
CSB68_0955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CSB68_0957	COG2351	hydroxyisourate hydrolase activity
CSB68_0965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSB68_0967	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSB68_0968	COG0642	Histidine kinase
CSB68_0969	COG0745	RESPONSE REGULATOR receiver
CSB68_0973	COG1794	racemase activity, acting on amino acids and derivatives
CSB68_0977	COG4372	Transposase
CSB68_0982	COG1301	dicarboxylic acid transport
CSB68_0984	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB68_0985	COG2011	ABC-type metal ion transport system permease component
CSB68_0986	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSB68_0987	COG1464	Belongs to the NlpA lipoprotein family
CSB68_0988	COG0151	Belongs to the GarS family
CSB68_0989	COG0138	bifunctional purine biosynthesis protein purh
CSB68_0990	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CSB68_0997	COG2308	Evidence 4 Homologs of previously reported genes of
CSB68_0999	COG1305	Transglutaminase-like
CSB68_1001	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSB68_1002	COG0305	Participates in initiation and elongation during chromosome replication
CSB68_1007	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CSB68_1009	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CSB68_1010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CSB68_1015	COG1649	PFAM Uncharacterised BCR, COG1649
CSB68_1015	COG0726	polysaccharide deacetylase
CSB68_1016	COG1215	transferase activity, transferring glycosyl groups
CSB68_1017	COG3658	cytochrome
CSB68_1019	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSB68_1022	COG0583	DNA-binding transcription factor activity
CSB68_1024	COG3328	transposase activity
CSB68_1027	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB68_1028	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB68_1031	COG1960	acyl-CoA dehydrogenase activity
CSB68_1033	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB68_1034	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB68_1035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB68_1040	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CSB68_1041	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CSB68_1043	COG2205	protein histidine kinase activity
CSB68_1044	COG0745	RESPONSE REGULATOR receiver
CSB68_1045	COG0174	glutamine synthetase
CSB68_1049	COG0729	surface antigen
CSB68_1054	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSB68_1055	COG2814	Major facilitator Superfamily
CSB68_1058	COG0583	DNA-binding transcription factor activity
CSB68_1061	COG1187	pseudouridine synthase activity
CSB68_1065	COG0802	atpase or kinase
CSB68_1066	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CSB68_1068	COG1923	regulation of RNA biosynthetic process
CSB68_1069	COG0697	spore germination
CSB68_1072	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB68_1075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSB68_1075	COG0519	Catalyzes the synthesis of GMP from XMP
CSB68_1076	COG4302	ethanolamine ammonia-lyase activity
CSB68_1077	COG4303	Ethanolamine ammonia lyase large subunit
CSB68_1078	COG0531	amino acid
CSB68_1082	COG1454	alcohol dehydrogenase
CSB68_1083	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB68_1085	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CSB68_1089	COG0308	aminopeptidase N
CSB68_1097	COG1605	Chorismate mutase
CSB68_1100	COG1309	transcriptional regulator
CSB68_1102	COG0668	transmembrane transport
CSB68_1107	COG4773	Receptor
CSB68_1112	COG0488	(ABC) transporter
CSB68_1113	COG0488	(ABC) transporter
CSB68_1114	COG0589	response to stress
CSB68_1118	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CSB68_1122	COG4372	Transposase
CSB68_1123	COG3135	benzoate transporter
CSB68_1124	COG1522	sequence-specific DNA binding
CSB68_1127	COG0583	DNA-binding transcription factor activity
CSB68_1129	COG0183	Belongs to the thiolase family
CSB68_1138	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSB68_1141	COG0824	Thioesterase
CSB68_1142	COG1454	alcohol dehydrogenase
CSB68_1144	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSB68_1150	COG0069	glutamate synthase activity
CSB68_1157	COG2814	Major facilitator Superfamily
CSB68_1160	COG0511	ligase activity, forming carbon-carbon bonds
CSB68_1163	COG1116	anion transmembrane transporter activity
CSB68_1163	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB68_1164	COG0745	RESPONSE REGULATOR receiver
CSB68_1165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB68_1165	COG2146	nitrite reductase [NAD(P)H] activity
CSB68_1166	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB68_1167	COG0243	molybdopterin cofactor binding
CSB68_1169	COG0243	molybdopterin cofactor binding
CSB68_1170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSB68_1173	COG0315	cyclic pyranopterin monophosphate synthase activity
CSB68_1173	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSB68_1174	COG0303	'Molybdopterin
CSB68_1176	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB68_1177	COG0697	spore germination
CSB68_1181	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CSB68_1182	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSB68_1194	COG2204	response regulator
CSB68_1195	COG3852	Histidine kinase
CSB68_1200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CSB68_1201	COG0575	Belongs to the CDS family
CSB68_1204	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSB68_1208	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB68_1210	COG2137	regulation of response to DNA damage stimulus
CSB68_1212	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSB68_1213	COG1011	Hydrolase
CSB68_1218	COG1522	sequence-specific DNA binding
CSB68_1220	COG1113	amino acid transport
CSB68_1223	COG0659	secondary active sulfate transmembrane transporter activity
CSB68_1224	COG2135	peptidase activity
CSB68_1229	COG5001	Diguanylate cyclase
CSB68_1229	COG3300	MHYT domain
CSB68_1233	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSB68_1233	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSB68_1233	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CSB68_1234	COG1105	Belongs to the carbohydrate kinase PfkB family
CSB68_1235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSB68_1235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CSB68_1241	COG0024	Methionine aminopeptidase
CSB68_1242	COG0583	DNA-binding transcription factor activity
CSB68_1244	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CSB68_1245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSB68_1246	COG0517	IMP dehydrogenase activity
CSB68_1246	COG0516	GMP reductase activity
CSB68_1252	COG0552	protein localization to endoplasmic reticulum
CSB68_1254	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CSB68_1256	COG1294	oxidase, subunit
CSB68_1259	COG1585	Membrane protein implicated in regulation of membrane protease activity
CSB68_1261	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSB68_1262	COG4774	siderophore transport
CSB68_1265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSB68_1266	COG0569	domain protein
CSB68_1267	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSB68_1273	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CSB68_1274	COG0542	response to heat
CSB68_1276	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSB68_1279	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB68_1279	COG1902	pentaerythritol trinitrate reductase activity
CSB68_1288	COG2323	membrane
CSB68_1289	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CSB68_1291	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB68_1292	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB68_1293	COG0183	Belongs to the thiolase family
CSB68_1294	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSB68_1295	COG0596	Alpha beta hydrolase
CSB68_1296	COG2271	Major facilitator Superfamily
CSB68_1297	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSB68_1298	COG3485	protocatechuate 3,4-dioxygenase
CSB68_1299	COG3485	protocatechuate 3,4-dioxygenase
CSB68_1300	COG0710	3-dehydroquinate dehydratase activity
CSB68_1301	COG3420	alginic acid biosynthetic process
CSB68_1302	COG3659	wide pore channel activity
CSB68_1303	COG4993	Dehydrogenase
CSB68_1305	COG2391	methyltransferase activity
CSB68_1308	COG1414	Transcriptional regulator
CSB68_1309	COG0583	DNA-binding transcription factor activity
CSB68_1310	COG1960	acyl-CoA dehydrogenase activity
CSB68_1315	COG2814	Major facilitator Superfamily
CSB68_1318	COG0154	amidase activity
CSB68_1322	COG4638	Rieske (2fe-2S)
CSB68_1324	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1326	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB68_1328	COG3733	amine oxidase
CSB68_1330	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_1332	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB68_1333	COG0183	Belongs to the thiolase family
CSB68_1334	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB68_1335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB68_1337	COG4829	muconolactone delta-isomerase
CSB68_1338	COG4948	Mandelate Racemase Muconate Lactonizing
CSB68_1339	COG0583	DNA-binding transcription factor activity
CSB68_1341	COG2186	Transcriptional regulator
CSB68_1345	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_1348	COG1902	pentaerythritol trinitrate reductase activity
CSB68_1348	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB68_1351	COG0789	Transcriptional regulator
CSB68_1356	COG1309	transcriptional regulator
CSB68_1357	COG0583	DNA-binding transcription factor activity
CSB68_1358	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1359	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1360	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1362	COG1960	acyl-CoA dehydrogenase activity
CSB68_1364	COG0318	PFAM AMP-dependent synthetase and ligase
CSB68_1379	COG0583	DNA-binding transcription factor activity
CSB68_1382	COG1566	PFAM secretion protein HlyD family protein
CSB68_1385	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_1386	COG0129	dihydroxy-acid dehydratase activity
CSB68_1388	COG0583	DNA-binding transcription factor activity
CSB68_1391	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSB68_1393	COG2084	Dehydrogenase
CSB68_1394	COG2207	Transcriptional regulator
CSB68_1395	COG1064	alcohol dehydrogenase
CSB68_1399	COG1120	ATPase activity
CSB68_1403	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSB68_1410	COG4372	Transposase
CSB68_1428	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CSB68_1441	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1444	COG2207	Transcriptional regulator
CSB68_1446	COG2205	protein histidine kinase activity
CSB68_1447	COG0745	RESPONSE REGULATOR receiver
CSB68_1448	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB68_1449	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSB68_1471	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSB68_1484	COG3433	isochorismatase activity
CSB68_1484	COG1535	isochorismatase
CSB68_1485	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1486	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSB68_1487	COG4149	molybdate abc transporter
CSB68_1488	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSB68_1490	COG4638	Rieske (2fe-2S)
CSB68_1491	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CSB68_1492	COG0543	2 iron, 2 sulfur cluster binding
CSB68_1492	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB68_1496	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB68_1498	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1499	COG0412	Dienelactone hydrolase
CSB68_1501	COG2207	Transcriptional regulator
CSB68_1502	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1503	COG2610	gluconate transmembrane transporter activity
CSB68_1511	COG0583	DNA-binding transcription factor activity
CSB68_1514	COG2031	fatty acid transporter
CSB68_1515	COG0183	Belongs to the thiolase family
CSB68_1516	COG0583	DNA-binding transcription factor activity
CSB68_1517	COG0583	DNA-binding transcription factor activity
CSB68_1520	COG1027	Aspartate ammonia-lyase
CSB68_1522	COG0477	Major facilitator Superfamily
CSB68_1526	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB68_1527	COG4521	taurine ABC transporter
CSB68_1532	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CSB68_1533	COG1733	regulation of RNA biosynthetic process
CSB68_1534	COG2207	Transcriptional regulator
CSB68_1534	COG3708	Transcriptional regulator
CSB68_1537	COG0730	response to heat
CSB68_1539	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB68_1539	COG3453	Protein conserved in bacteria
CSB68_1541	COG3781	membrane
CSB68_1542	COG1063	alcohol dehydrogenase
CSB68_1544	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB68_1545	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSB68_1546	COG0022	dehydrogenase e1 component
CSB68_1547	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSB68_1548	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CSB68_1551	COG3706	GGDEF domain
CSB68_1554	COG0133	tryptophan synthase activity
CSB68_1556	COG2226	methyltransferase
CSB68_1567	COG0842	Transport permease protein
CSB68_1568	COG0842	Transport permease protein
CSB68_1569	COG0842	Transport permease protein
CSB68_1570	COG1131	(ABC) transporter
CSB68_1573	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB68_1574	COG4773	Receptor
CSB68_1577	COG0730	response to heat
CSB68_1578	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSB68_1581	COG0406	alpha-ribazole phosphatase activity
CSB68_1592	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSB68_1594	COG4264	IucA IucC family
CSB68_1595	COG4264	IucA IucC family
CSB68_1596	COG2814	Major facilitator Superfamily
CSB68_1599	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSB68_1602	COG1960	acyl-CoA dehydrogenase activity
CSB68_1603	COG1960	acyl-CoA dehydrogenase activity
CSB68_1604	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSB68_1605	COG2207	Transcriptional regulator
CSB68_1606	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSB68_1607	COG0776	regulation of translation
CSB68_1612	COG0822	iron-sulfur transferase activity
CSB68_1613	COG0316	Belongs to the HesB IscA family
CSB68_1619	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSB68_1623	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSB68_1624	COG0702	epimerase
CSB68_1631	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSB68_1633	COG0339	signal peptide processing
CSB68_1635	COG4166	transmembrane transport
CSB68_1642	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CSB68_1653	COG1196	nuclear chromosome segregation
CSB68_1653	COG0741	lytic transglycosylase activity
CSB68_1653	COG0739	heme binding
CSB68_1654	COG4372	Transposase
CSB68_1662	COG3646	Phage regulatory protein
CSB68_1684	COG0305	Participates in initiation and elongation during chromosome replication
CSB68_1697	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CSB68_1703	COG0776	regulation of translation
CSB68_1707	COG0590	tRNA wobble adenosine to inosine editing
CSB68_1716	COG0084	hydrolase, TatD family'
CSB68_1720	COG1663	tetraacyldisaccharide 4'-kinase activity
CSB68_1721	COG1132	(ABC) transporter
CSB68_1723	COG0811	peptide transport
CSB68_1724	COG1475	DNA binding
CSB68_1725	COG1192	Involved in chromosome partitioning
CSB68_1727	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSB68_1730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSB68_1731	COG0191	fructose-bisphosphate aldolase activity
CSB68_1735	COG0424	maF-like protein
CSB68_1736	COG2850	peptidyl-arginine hydroxylation
CSB68_1738	COG0640	Transcriptional regulator
CSB68_1740	COG3619	membrane
CSB68_1741	COG3122	Protein conserved in bacteria
CSB68_1742	COG1132	(ABC) transporter
CSB68_1746	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CSB68_1747	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSB68_1750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CSB68_1750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CSB68_1750	COG0506	proline dehydrogenase activity
CSB68_1751	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSB68_1754	COG3698	Phosphodiester glycosidase
CSB68_1756	COG2353	YceI-like domain
CSB68_1758	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSB68_1769	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSB68_1769	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSB68_1775	COG3539	Fimbrial protein
CSB68_1776	COG3121	Chaperone
CSB68_1784	COG0697	spore germination
CSB68_1786	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CSB68_1788	COG0583	DNA-binding transcription factor activity
CSB68_1793	COG1309	transcriptional regulator
CSB68_1809	COG0739	heme binding
CSB68_1809	COG1196	nuclear chromosome segregation
CSB68_1809	COG0741	lytic transglycosylase activity
CSB68_1835	COG0305	Participates in initiation and elongation during chromosome replication
CSB68_1850	COG1522	sequence-specific DNA binding
CSB68_1852	COG1126	abc transporter atp-binding protein
CSB68_1853	COG0765	amino acid transport
CSB68_1854	COG0765	amino acid transport
CSB68_1860	COG1464	Belongs to the NlpA lipoprotein family
CSB68_1862	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSB68_1863	COG2011	ABC-type metal ion transport system permease component
CSB68_1864	COG0012	GTP binding
CSB68_1869	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CSB68_1877	COG0386	Belongs to the glutathione peroxidase family
CSB68_1879	COG0436	Aminotransferase
CSB68_1887	COG3634	alkyl hydroperoxide reductase activity
CSB68_1890	COG0583	DNA-binding transcription factor activity
CSB68_1891	COG0798	PFAM Bile acid sodium symporter
CSB68_1892	COG0640	Transcriptional regulator
CSB68_1895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CSB68_1897	COG0583	DNA-binding transcription factor activity
CSB68_1899	COG1953	Uracil, thiamine, allantoin
CSB68_1901	COG2175	clavaminate synthase activity
CSB68_1902	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB68_1903	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CSB68_1904	COG4521	taurine ABC transporter
CSB68_1906	COG0477	Major facilitator Superfamily
CSB68_1911	COG1271	oxidase subunit
CSB68_1912	COG1294	oxidase, subunit
CSB68_1914	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB68_1918	COG4372	Transposase
CSB68_1922	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSB68_1926	COG3052	prosthetic group binding
CSB68_1927	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CSB68_1929	COG0583	DNA-binding transcription factor activity
CSB68_1931	COG2814	Major facilitator Superfamily
CSB68_1934	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB68_1935	COG1346	cytolysis
CSB68_1937	COG0583	DNA-binding transcription factor activity
CSB68_1938	COG0625	glutathione transferase activity
CSB68_1939	COG0625	glutathione transferase activity
CSB68_1940	COG0583	DNA-binding transcription factor activity
CSB68_1943	COG1045	serine acetyltransferase
CSB68_1944	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSB68_1945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSB68_1946	COG1280	lysine exporter protein (LysE YggA)
CSB68_1949	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB68_1950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB68_1951	COG1126	abc transporter atp-binding protein
CSB68_1952	COG0765	amino acid transport
CSB68_1953	COG0765	amino acid transport
CSB68_1957	COG2205	protein histidine kinase activity
CSB68_1957	COG0784	Response regulator, receiver
CSB68_1961	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSB68_1965	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1975	COG0583	DNA-binding transcription factor activity
CSB68_1979	COG0318	PFAM AMP-dependent synthetase and ligase
CSB68_1980	COG1309	transcriptional regulator
CSB68_1981	COG1960	acyl-CoA dehydrogenase activity
CSB68_1982	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSB68_1983	COG1024	Enoyl-CoA hydratase
CSB68_1986	COG0583	DNA-binding transcription factor activity
CSB68_1989	COG1960	acyl-CoA dehydrogenase activity
CSB68_1991	COG2814	Major facilitator Superfamily
CSB68_1993	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB68_1994	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB68_1995	COG2814	Major facilitator Superfamily
CSB68_1996	COG1960	acyl-CoA dehydrogenase activity
CSB68_1997	COG1024	Enoyl-CoA hydratase
CSB68_1998	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_1999	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB68_2000	COG0183	Belongs to the thiolase family
CSB68_2002	COG2814	Major facilitator Superfamily
CSB68_2004	COG1024	Enoyl-CoA hydratase
CSB68_2007	COG1960	acyl-CoA dehydrogenase activity
CSB68_2008	COG2814	Major facilitator Superfamily
CSB68_2009	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSB68_2010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSB68_2013	COG3842	ATPase activity
CSB68_2014	COG1840	ABC-type Fe3 transport system, periplasmic component
CSB68_2016	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB68_2017	COG1414	Transcriptional regulator
CSB68_2019	COG0583	DNA-binding transcription factor activity
CSB68_2020	COG3038	cytochrome b561
CSB68_2021	COG0753	catalase activity
CSB68_2022	COG2271	Major facilitator Superfamily
CSB68_2023	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSB68_2024	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSB68_2027	COG2207	Transcriptional regulator
CSB68_2029	COG1278	Cold shock
CSB68_2037	COG2050	protein possibly involved in aromatic compounds catabolism
CSB68_2039	COG3327	negative regulation of DNA-templated transcription, initiation
CSB68_2040	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CSB68_2041	COG0183	Belongs to the thiolase family
CSB68_2042	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB68_2043	COG1024	Enoyl-CoA hydratase
CSB68_2044	COG1024	Enoyl-CoA hydratase
CSB68_2045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB68_2046	COG2151	metal-sulfur cluster biosynthetic enzyme
CSB68_2047	COG3396	Phenylacetate-CoA oxygenase
CSB68_2048	COG3460	Phenylacetate-CoA oxygenase
CSB68_2049	COG3396	Phenylacetate-CoA oxygenase
CSB68_2050	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_2050	COG2030	dehydratase
CSB68_2051	COG1760	l-serine dehydratase
CSB68_2052	COG0531	amino acid
CSB68_2053	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_2058	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSB68_2062	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB68_2064	COG0789	Transcriptional regulator
CSB68_2065	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSB68_2068	COG2807	transmembrane transport
CSB68_2069	COG0590	tRNA wobble adenosine to inosine editing
CSB68_2071	COG0583	DNA-binding transcription factor activity
CSB68_2079	COG2885	chlorophyll binding
CSB68_2079	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CSB68_2094	COG1116	anion transmembrane transporter activity
CSB68_2095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB68_2097	COG0864	Transcriptional regulator
CSB68_2099	COG1733	regulation of RNA biosynthetic process
CSB68_2100	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB68_2101	COG0439	Biotin carboxylase
CSB68_2104	COG1063	alcohol dehydrogenase
CSB68_2106	COG1309	transcriptional regulator
CSB68_2110	COG4372	Transposase
CSB68_2117	COG0038	chloride channel
CSB68_2118	COG4770	biotin carboxylase activity
CSB68_2122	COG1914	H( )-stimulated, divalent metal cation uptake system
CSB68_2123	COG0583	DNA-binding transcription factor activity
CSB68_2128	COG3209	COG3209 Rhs family protein
CSB68_2129	COG3501	Rhs element vgr protein
CSB68_2134	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB68_2139	COG2814	Major facilitator Superfamily
CSB68_2141	COG1560	Kdo2-lipid A biosynthetic process
CSB68_2143	COG5006	permease, DMT superfamily
CSB68_2144	COG1522	sequence-specific DNA binding
CSB68_2147	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CSB68_2155	COG1538	Outer membrane efflux protein
CSB68_2156	COG1137	ATPase activity
CSB68_2157	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CSB68_2159	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CSB68_2188	COG5484	DNA packaging
CSB68_2188	COG3728	DNA packaging
CSB68_2214	COG1733	regulation of RNA biosynthetic process
CSB68_2215	COG2814	Major facilitator Superfamily
CSB68_2222	COG1278	Cold shock
CSB68_2223	COG1280	lysine exporter protein (LysE YggA)
CSB68_2229	COG1570	exodeoxyribonuclease VII activity
CSB68_2245	COG2871	sodium ion transport
CSB68_2247	COG0583	DNA-binding transcription factor activity
CSB68_2249	COG4638	Rieske (2fe-2S)
CSB68_2250	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CSB68_2251	COG0543	2 iron, 2 sulfur cluster binding
CSB68_2251	COG0633	Ferredoxin
CSB68_2252	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_2253	COG3135	benzoate transporter
CSB68_2254	COG2814	Major facilitator Superfamily
CSB68_2257	COG1643	Atp-dependent helicase
CSB68_2258	COG0450	alkyl hydroperoxide reductase
CSB68_2260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CSB68_2262	COG3634	alkyl hydroperoxide reductase activity
CSB68_2266	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSB68_2267	COG0625	glutathione transferase activity
CSB68_2269	COG2885	chlorophyll binding
CSB68_2279	COG1765	OsmC-like protein
CSB68_2281	COG0667	Aldo Keto reductase
CSB68_2282	COG0667	Aldo Keto reductase
CSB68_2285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CSB68_2289	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSB68_2293	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CSB68_2295	COG3038	cytochrome b561
CSB68_2296	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CSB68_2297	COG2252	PERMEase
CSB68_2299	COG2072	flavoprotein involved in K transport
CSB68_2302	COG1741	Belongs to the pirin family
CSB68_2303	COG1309	transcriptional regulator
CSB68_2305	COG0300	oxidoreductase activity
CSB68_2306	COG2072	flavoprotein involved in K transport
CSB68_2307	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CSB68_2316	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSB68_2319	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB68_2322	COG2814	Major facilitator Superfamily
CSB68_2323	COG1024	Enoyl-CoA hydratase
CSB68_2324	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_2326	COG1960	acyl-CoA dehydrogenase activity
CSB68_2331	COG2186	Transcriptional regulator
CSB68_2332	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_2335	COG4948	Mandelate Racemase Muconate Lactonizing
CSB68_2336	COG2271	Major facilitator Superfamily
CSB68_2337	COG2721	sulfolactate sulfo-lyase activity
CSB68_2338	COG0697	spore germination
CSB68_2346	COG1113	amino acid transport
CSB68_2350	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_2354	COG0531	amino acid
CSB68_2356	COG1113	amino acid transport
CSB68_2362	COG3209	COG3209 Rhs family protein
CSB68_2363	COG3501	Rhs element vgr protein
CSB68_2368	COG4269	membrane
CSB68_2371	COG1902	pentaerythritol trinitrate reductase activity
CSB68_2371	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB68_2373	COG5001	Diguanylate cyclase
CSB68_2373	COG4251	negative regulation of phosphorylation
CSB68_2373	COG2203	Gaf domain
CSB68_2373	COG3706	GGDEF domain
CSB68_2375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB68_2379	COG4172	Belongs to the ABC transporter superfamily
CSB68_2380	COG4239	(ABC) transporter, permease
CSB68_2381	COG4174	ABC transporter (Permease)
CSB68_2383	COG0741	lytic transglycosylase activity
CSB68_2383	COG1388	LysM domain
CSB68_2383	COG0741	lytic transglycosylase activity
CSB68_2383	COG1388	LysM domain
CSB68_2384	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB68_2392	COG0583	DNA-binding transcription factor activity
CSB68_2393	COG1279	arginine transmembrane transporter activity
CSB68_2397	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB68_2398	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB68_2399	COG0006	proline dipeptidase activity
CSB68_2406	COG1278	Cold shock
CSB68_2471	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSB68_2474	COG3384	dioxygenase
CSB68_2476	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSB68_2477	COG2878	Part of a membrane complex involved in electron transport
CSB68_2478	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSB68_2483	COG0768	penicillin binding
CSB68_2484	COG0742	ribosomal rna small subunit methyltransferase
CSB68_2487	COG0830	nickel cation binding
CSB68_2489	COG0804	urea catabolic process
CSB68_2498	COG1253	flavin adenine dinucleotide binding
CSB68_2499	COG2851	Citrate transporter
CSB68_2509	COG1773	rubredoxin
CSB68_2510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB68_2512	COG0583	DNA-binding transcription factor activity
CSB68_2517	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CSB68_2518	COG4181	ATPase activity
CSB68_2528	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSB68_2534	COG0306	phosphate transporter
CSB68_2537	COG3958	Transketolase
CSB68_2538	COG3959	Transketolase, thiamine diphosphate binding domain
CSB68_2539	COG2271	Major facilitator Superfamily
CSB68_2540	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_2541	COG0583	DNA-binding transcription factor activity
CSB68_2544	COG2223	nitrite transmembrane transporter activity
CSB68_2545	COG2207	Transcriptional regulator
CSB68_2546	COG2066	Belongs to the glutaminase family
CSB68_2547	COG0242	peptide deformylase activity
CSB68_2549	COG0477	Major facilitator Superfamily
CSB68_2551	COG0028	Belongs to the TPP enzyme family
CSB68_2552	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_2554	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_2555	COG2267	carboxylic ester hydrolase activity
CSB68_2557	COG2271	Major facilitator Superfamily
CSB68_2560	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_2563	COG1414	Transcriptional regulator
CSB68_2566	COG1024	Enoyl-CoA hydratase
CSB68_2568	COG1215	transferase activity, transferring glycosyl groups
CSB68_2569	COG0726	polysaccharide deacetylase
CSB68_2569	COG1649	PFAM Uncharacterised BCR, COG1649
CSB68_2571	COG4681	YaeQ
CSB68_2573	COG0523	cobalamin synthesis protein
CSB68_2575	COG1607	acyl-coa hydrolase
CSB68_2577	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB68_2578	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB68_2579	COG1309	transcriptional regulator
CSB68_2584	COG2040	homocysteine
CSB68_2585	COG0531	amino acid
CSB68_2591	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB68_2592	COG0477	Major facilitator Superfamily
CSB68_2603	COG0583	DNA-binding transcription factor activity
CSB68_2612	COG1053	succinate dehydrogenase
CSB68_2615	COG0402	S-adenosylhomocysteine deaminase activity
CSB68_2617	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CSB68_2638	COG4372	Transposase
CSB68_2645	COG4372	Transposase
CSB68_2646	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CSB68_2647	COG0732	type I restriction modification DNA specificity domain
CSB68_2648	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CSB68_2651	COG0405	Gamma-glutamyltransferase
CSB68_2652	COG2814	Major facilitator Superfamily
CSB68_2654	COG2050	protein possibly involved in aromatic compounds catabolism
CSB68_2657	COG1090	epimerase
CSB68_2661	COG0420	3'-5' exonuclease activity
CSB68_2666	COG0735	belongs to the Fur family
CSB68_2667	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSB68_2671	COG0121	glutamine amidotransferase
CSB68_2674	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSB68_2676	COG0210	DNA helicase
CSB68_2677	COG2885	chlorophyll binding
CSB68_2678	COG0204	Acyl-transferase
CSB68_2681	COG2894	cell division
CSB68_2684	COG1280	lysine exporter protein (LysE YggA)
CSB68_2685	COG1674	ftsk spoiiie
CSB68_2685	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CSB68_2687	COG0492	ferredoxin-NADP+ reductase activity
CSB68_2688	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CSB68_2690	COG0456	acetyltransferase
CSB68_2702	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CSB68_2702	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSB68_2706	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_2710	COG0473	3-isopropylmalate dehydrogenase activity
CSB68_2711	COG0583	DNA-binding transcription factor activity
CSB68_2714	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSB68_2719	COG0564	pseudouridine synthase activity
CSB68_2721	COG0358	DNA primase activity
CSB68_2724	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CSB68_2729	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSB68_2735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSB68_2737	COG0351	phosphomethylpyrimidine kinase
CSB68_2737	COG0352	thiamine-phosphate diphosphorylase activity
CSB68_2737	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSB68_2738	COG1652	LysM domain
CSB68_2743	COG1399	metal-binding, possibly nucleic acid-binding protein
CSB68_2744	COG3101	peptidyl-lysine hydroxylation
CSB68_2745	COG0009	L-threonylcarbamoyladenylate synthase
CSB68_2746	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CSB68_2747	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CSB68_2750	COG4106	trans-aconitate 2-methyltransferase activity
CSB68_2753	COG2226	methyltransferase
CSB68_2753	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB68_2753	COG0596	Alpha beta hydrolase
CSB68_2754	COG1877	trehalose-phosphatase activity
CSB68_2755	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CSB68_2756	COG2223	nitrite transmembrane transporter activity
CSB68_2760	COG1196	nuclear chromosome segregation
CSB68_2762	COG0730	response to heat
CSB68_2765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSB68_2767	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSB68_2778	COG0489	protein tyrosine kinase activity
CSB68_2780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB68_2780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB68_2786	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CSB68_2787	COG2081	HI0933 family
CSB68_2789	COG0668	transmembrane transport
CSB68_2793	COG0583	DNA-binding transcription factor activity
CSB68_2798	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSB68_2799	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSB68_2805	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CSB68_2812	COG4372	Transposase
CSB68_2813	COG3706	GGDEF domain
CSB68_2815	COG2205	protein histidine kinase activity
CSB68_2816	COG0745	RESPONSE REGULATOR receiver
CSB68_2819	COG4372	Transposase
CSB68_2822	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSB68_2829	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB68_2830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CSB68_2834	COG1473	amidohydrolase
CSB68_2836	COG0583	DNA-binding transcription factor activity
CSB68_2839	COG0583	DNA-binding transcription factor activity
CSB68_2840	COG1053	succinate dehydrogenase
CSB68_2842	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSB68_2843	COG2814	Major facilitator Superfamily
CSB68_2844	COG1960	acyl-CoA dehydrogenase activity
CSB68_2846	COG0583	DNA-binding transcription factor activity
CSB68_2847	COG1063	alcohol dehydrogenase
CSB68_2853	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CSB68_2854	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CSB68_2855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSB68_2858	COG3667	copper resistance
CSB68_2859	COG2132	Multicopper oxidase
CSB68_2861	COG0561	phosphatase activity
CSB68_2862	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSB68_2863	COG4372	Transposase
CSB68_2867	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CSB68_2870	COG1214	PFAM Peptidase M22, glycoprotease
CSB68_2880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSB68_2882	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CSB68_2883	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CSB68_2884	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CSB68_2896	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSB68_2898	COG1846	Transcriptional regulator
CSB68_2899	COG1764	response to oxidative stress
CSB68_2907	COG0037	tRNA processing
CSB68_2909	COG0248	Ppx GppA phosphatase
CSB68_2914	COG0072	phenylalanine-tRNA ligase activity
CSB68_2919	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CSB68_2922	COG1238	metal cluster binding
CSB68_2923	COG0625	glutathione transferase activity
CSB68_2926	COG0318	PFAM AMP-dependent synthetase and ligase
CSB68_2927	COG3028	Belongs to the UPF0307 family
CSB68_2928	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSB68_2932	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSB68_2933	COG0617	tRNA 3'-terminal CCA addition
CSB68_2934	COG1555	photosystem II stabilization
CSB68_2935	COG3956	TIGRFAM MazG family protein
CSB68_2937	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSB68_2941	COG5002	protein histidine kinase activity
CSB68_2941	COG2205	protein histidine kinase activity
CSB68_2941	COG0784	Response regulator, receiver
CSB68_2942	COG1024	Enoyl-CoA hydratase
CSB68_2943	COG2084	Dehydrogenase
CSB68_2944	COG3622	Belongs to the hyi family
CSB68_2947	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CSB68_2948	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CSB68_2949	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CSB68_2950	COG0697	spore germination
CSB68_2952	COG2814	Major facilitator Superfamily
CSB68_2953	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSB68_2955	COG0583	DNA-binding transcription factor activity
CSB68_2957	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSB68_2959	COG0084	hydrolase, TatD family'
CSB68_2962	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CSB68_2968	COG0440	acetolactate synthase activity
CSB68_2969	COG0028	Belongs to the TPP enzyme family
CSB68_2974	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB68_2975	COG0577	efflux transmembrane transporter activity
CSB68_2975	COG1136	(ABC) transporter
CSB68_2976	COG1538	Outer membrane efflux protein
CSB68_2979	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CSB68_2980	COG1162	GTPase activity
CSB68_2982	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSB68_2990	COG1426	Protein conserved in bacteria
CSB68_2997	COG0793	Belongs to the peptidase S41A family
CSB68_3000	COG2267	carboxylic ester hydrolase activity
CSB68_3002	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_3003	COG3265	gluconokinase activity
CSB68_3005	COG0800	Aldolase
CSB68_3007	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSB68_3008	COG0280	phosphate acetyltransferase
CSB68_3008	COG0857	belongs to the CobB CobQ family
CSB68_3009	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CSB68_3009	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CSB68_3015	COG0740	serine-type endopeptidase activity
CSB68_3017	COG4774	siderophore transport
CSB68_3019	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSB68_3021	COG2813	Specifically methylates the guanine in position
CSB68_3021	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB68_3044	COG0788	formyltetrahydrofolate deformylase activity
CSB68_3047	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CSB68_3048	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSB68_3049	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB68_3049	COG4651	solute:proton antiporter activity
CSB68_3053	COG0724	RNA recognition motif
CSB68_3054	COG0210	DNA helicase
CSB68_3059	COG1733	regulation of RNA biosynthetic process
CSB68_3063	COG1280	lysine exporter protein (LysE YggA)
CSB68_3064	COG1560	Kdo2-lipid A biosynthetic process
CSB68_3066	COG1301	dicarboxylic acid transport
CSB68_3068	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSB68_3077	COG0473	3-isopropylmalate dehydrogenase activity
CSB68_3082	COG0583	DNA-binding transcription factor activity
CSB68_3091	COG0583	DNA-binding transcription factor activity
CSB68_3093	COG0625	glutathione transferase activity
CSB68_3094	COG2378	regulation of single-species biofilm formation
CSB68_3095	COG0546	phosphoglycolate phosphatase activity
CSB68_3098	COG1530	ribonuclease E activity
CSB68_3102	COG0583	DNA-binding transcription factor activity
CSB68_3103	COG4221	oxidoreductase activity
CSB68_3104	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSB68_3106	COG0534	Mate efflux family protein
CSB68_3109	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CSB68_3112	COG4372	Transposase
CSB68_3119	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CSB68_3120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB68_3124	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CSB68_3126	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CSB68_3126	COG0644	oxidoreductase
CSB68_3128	COG0425	Belongs to the sulfur carrier protein TusA family
CSB68_3129	COG4535	Mg2 and Co2 transporter CorC
CSB68_3131	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB68_3135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSB68_3136	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB68_3136	COG0475	glutathione-regulated potassium exporter activity
CSB68_3139	COG0484	heat shock protein binding
CSB68_3140	COG0789	Transcriptional regulator
CSB68_3141	COG0598	Magnesium transport protein CorA
CSB68_3145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB68_3146	COG1074	ATP-dependent DNA helicase activity
CSB68_3147	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CSB68_3151	COG2226	methyltransferase
CSB68_3154	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB68_3155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CSB68_3158	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSB68_3158	COG2111	Na H antiporter
CSB68_3159	COG1006	Multisubunit Na H antiporter MnhC subunit
CSB68_3160	COG0651	ATP synthesis coupled electron transport
CSB68_3162	COG2212	antiporter activity
CSB68_3166	COG0195	Participates in both transcription termination and antitermination
CSB68_3176	COG0237	dephospho-CoA kinase activity
CSB68_3178	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSB68_3182	COG0497	DNA recombination
CSB68_3184	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CSB68_3190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSB68_3190	COG2169	Transcriptional regulator
CSB68_3191	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSB68_3203	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSB68_3206	COG0326	Molecular chaperone. Has ATPase activity
CSB68_3209	COG2056	Na+-H+ antiporter family
CSB68_3210	COG0596	Alpha beta hydrolase
CSB68_3229	COG0546	phosphoglycolate phosphatase activity
CSB68_3230	COG1716	ATPase activity
CSB68_3239	COG0181	hydroxymethylbilane synthase activity
CSB68_3241	COG3275	phosphorelay sensor kinase activity
CSB68_3245	COG1538	Outer membrane efflux protein
CSB68_3246	COG0697	spore germination
CSB68_3251	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSB68_3252	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSB68_3253	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSB68_3254	COG0772	Belongs to the SEDS family
CSB68_3259	COG4974	Belongs to the 'phage' integrase family
CSB68_3260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB68_3262	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSB68_3264	COG2197	response regulator
CSB68_3267	COG0793	Belongs to the peptidase S41A family
CSB68_3268	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CSB68_3269	COG0795	lipopolysaccharide-transporting ATPase activity
CSB68_3277	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSB68_3277	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSB68_3279	COG0004	ammonium transporteR
CSB68_3280	COG0347	Belongs to the P(II) protein family
CSB68_3282	COG0606	chelatase, subunit chli
CSB68_3286	COG0659	secondary active sulfate transmembrane transporter activity
CSB68_3287	COG0589	response to stress
CSB68_3289	COG0640	Transcriptional regulator
CSB68_3291	COG0798	PFAM Bile acid sodium symporter
CSB68_3292	COG0431	NADPH-dependent FMN reductase
CSB68_3293	COG0492	ferredoxin-NADP+ reductase activity
CSB68_3294	COG2072	flavoprotein involved in K transport
CSB68_3300	COG0606	chelatase, subunit chli
CSB68_3301	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB68_3303	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB68_3307	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSB68_3310	COG0318	PFAM AMP-dependent synthetase and ligase
CSB68_3312	COG0477	Major facilitator Superfamily
CSB68_3313	COG2860	membrane
CSB68_3315	COG1253	flavin adenine dinucleotide binding
CSB68_3319	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSB68_3329	COG0655	NAD(P)H dehydrogenase (quinone) activity
CSB68_3331	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSB68_3335	COG4372	Transposase
CSB68_3341	COG1309	transcriptional regulator
CSB68_3348	COG0758	DNA mediated transformation
CSB68_3350	COG0697	spore germination
CSB68_3351	COG1309	transcriptional regulator
CSB68_3355	COG4372	Transposase
CSB68_3357	COG0386	Belongs to the glutathione peroxidase family
CSB68_3370	COG1121	(ABC) transporter
CSB68_3371	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSB68_3372	COG1280	lysine exporter protein (LysE YggA)
CSB68_3375	COG2837	iron assimilation
CSB68_3376	COG0281	malic enzyme
CSB68_3385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSB68_3385	COG0519	Catalyzes the synthesis of GMP from XMP
CSB68_3386	COG4399	Belongs to the UPF0754 family
CSB68_3387	COG2259	Doxx family
CSB68_3388	COG0586	Pfam SNARE associated Golgi protein
CSB68_3391	COG1192	Involved in chromosome partitioning
CSB68_3393	COG0271	Belongs to the BolA IbaG family
CSB68_3401	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSB68_3401	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CSB68_3401	COG3321	synthase
CSB68_3401	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSB68_3402	COG1960	acyl-CoA dehydrogenase activity
CSB68_3404	COG2197	response regulator
CSB68_3406	COG3916	Acyl-homoserine-lactone synthase
CSB68_3407	COG1846	Transcriptional regulator
CSB68_3408	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CSB68_3412	COG0019	diaminopimelate decarboxylase activity
CSB68_3413	COG0477	Major facilitator Superfamily
CSB68_3414	COG1024	Enoyl-CoA hydratase
CSB68_3415	COG1024	Enoyl-CoA hydratase
CSB68_3416	COG1960	acyl-CoA dehydrogenase activity
CSB68_3417	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB68_3421	COG1113	amino acid transport
CSB68_3422	COG1113	amino acid transport
CSB68_3423	COG0251	oxidation-reduction process
CSB68_3426	COG1522	sequence-specific DNA binding
CSB68_3431	COG0564	pseudouridine synthase activity
CSB68_3442	COG1196	nuclear chromosome segregation
CSB68_3443	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CSB68_3446	COG1802	Transcriptional regulator
CSB68_3448	COG1448	Aminotransferase
CSB68_3449	COG0277	FAD linked oxidase domain protein
CSB68_3451	COG2186	Transcriptional regulator
CSB68_3453	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSB68_3456	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSB68_3457	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSB68_3458	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSB68_3469	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSB68_3470	COG1596	polysaccharide export
CSB68_3475	COG0728	peptidoglycan biosynthetic process
CSB68_3476	COG3023	N-Acetylmuramoyl-L-alanine amidase
CSB68_3488	COG0546	phosphoglycolate phosphatase activity
CSB68_3489	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_3493	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB68_3494	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB68_3495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSB68_3496	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB68_3497	COG1116	anion transmembrane transporter activity
CSB68_3498	COG1309	transcriptional regulator
CSB68_3499	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSB68_3501	COG0196	riboflavin kinase activity
CSB68_3502	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CSB68_3504	COG1047	Peptidyl-prolyl cis-trans
CSB68_3512	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSB68_3517	COG0583	DNA-binding transcription factor activity
CSB68_3523	COG2951	lytic endotransglycosylase activity
CSB68_3524	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CSB68_3528	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSB68_3530	COG0671	phosphoesterase, PA-phosphatase related
CSB68_3531	COG0861	Integral membrane protein TerC family
CSB68_3533	COG0754	glutathionylspermidine amidase activity
CSB68_3535	COG0402	S-adenosylhomocysteine deaminase activity
CSB68_3539	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB68_3540	COG1230	cation diffusion facilitator family transporter
CSB68_3544	COG0706	membrane insertase activity
CSB68_3547	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CSB68_3549	COG0592	DNA-directed DNA polymerase activity
CSB68_3551	COG0187	DNA topoisomerase II activity
CSB68_3553	COG0586	Pfam SNARE associated Golgi protein
CSB68_3554	COG0488	(ABC) transporter
CSB68_3563	COG0596	Alpha beta hydrolase
CSB68_3564	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CSB68_3565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CSB68_3572	COG4372	Transposase
CSB68_3578	COG0733	neurotransmitter:sodium symporter activity
CSB68_3586	COG2233	PERMEase
CSB68_3589	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB68_3596	COG2814	Major facilitator Superfamily
CSB68_3597	COG0656	L-ascorbic acid biosynthetic process
CSB68_3598	COG0583	DNA-binding transcription factor activity
CSB68_3600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB68_3601	COG1064	alcohol dehydrogenase
CSB68_3602	COG2818	Glycosylase
CSB68_3605	COG1194	a g-specific adenine glycosylase
CSB68_3609	COG2983	Belongs to the UPF0260 family
CSB68_3610	COG2133	pyrroloquinoline quinone binding
CSB68_3611	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSB68_3612	COG2116	formate transmembrane transporter activity
CSB68_3617	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB68_3618	COG1335	isochorismatase
CSB68_3619	COG0385	Bile acid
CSB68_3620	COG0534	Mate efflux family protein
CSB68_3621	COG1683	Conserved Protein
CSB68_3625	COG0625	glutathione transferase activity
CSB68_3627	COG1113	amino acid transport
CSB68_3629	COG0523	cobalamin synthesis protein
CSB68_3631	COG2188	Transcriptional regulator
CSB68_3637	COG0010	Belongs to the arginase family
CSB68_3640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CSB68_3641	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSB68_3643	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSB68_3645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CSB68_3650	COG3830	Belongs to the UPF0237 family
CSB68_3650	COG0560	Phosphoserine phosphatase
CSB68_3665	COG0534	Mate efflux family protein
CSB68_3666	COG0436	Aminotransferase
CSB68_3667	COG2733	membrane
CSB68_3670	COG2918	glutathione biosynthetic process
CSB68_3672	COG3501	Rhs element vgr protein
CSB68_3673	COG1388	LysM domain
CSB68_3673	COG0791	NLP P60 protein
CSB68_3676	COG3150	esterase
CSB68_3679	COG1028	Short-chain dehydrogenase reductase Sdr
CSB68_3680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CSB68_3682	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB68_3684	COG2233	PERMEase
CSB68_3685	COG2351	hydroxyisourate hydrolase activity
CSB68_3692	COG3706	GGDEF domain
CSB68_3695	COG1393	Belongs to the ArsC family
CSB68_3696	COG0708	Exodeoxyribonuclease III
CSB68_3700	COG0189	ligase activity
CSB68_3704	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CSB68_3706	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSB68_3709	COG4372	Transposase
CSB68_3712	COG4942	peptidase
CSB68_3714	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSB68_3716	COG2119	membrane
CSB68_3719	COG4372	Transposase
CSB68_3720	COG2119	membrane
CSB68_3721	COG4774	siderophore transport
CSB68_3722	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB68_3722	COG0426	domain, Protein
CSB68_3727	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSB68_3733	COG1902	pentaerythritol trinitrate reductase activity
CSB68_3734	COG1519	Transferase
CSB68_3735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSB68_3736	COG0668	transmembrane transport
CSB68_3738	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB68_3739	COG1335	isochorismatase
CSB68_3740	COG1522	sequence-specific DNA binding
CSB68_3745	COG2198	Histidine kinase
CSB68_3745	COG2205	protein histidine kinase activity
CSB68_3745	COG0784	Response regulator, receiver
CSB68_3746	COG3162	membrane
CSB68_3747	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSB68_3749	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB68_3751	COG3706	GGDEF domain
CSB68_3753	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSB68_3754	COG1309	transcriptional regulator
CSB68_3758	COG0351	phosphomethylpyrimidine kinase
CSB68_3758	COG0352	thiamine-phosphate diphosphorylase activity
CSB68_3758	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSB68_3760	COG2814	Major facilitator Superfamily
CSB68_3763	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CSB68_3765	COG1113	amino acid transport
CSB68_3767	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSB68_3768	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_3770	COG1335	isochorismatase
CSB68_3775	COG4372	Transposase
CSB68_3781	COG2814	Major facilitator Superfamily
CSB68_3782	COG0583	DNA-binding transcription factor activity
CSB68_3786	COG0667	Aldo Keto reductase
CSB68_3795	COG1733	regulation of RNA biosynthetic process
CSB68_3796	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB68_3810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSB68_3813	COG2329	Antibiotic biosynthesis monooxygenase
CSB68_3819	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CSB68_3825	COG0427	acetyl-CoA hydrolase
CSB68_3827	COG0745	RESPONSE REGULATOR receiver
CSB68_3829	COG0659	secondary active sulfate transmembrane transporter activity
CSB68_3830	COG4221	oxidoreductase activity
CSB68_3832	COG0488	(ABC) transporter
CSB68_3851	COG0833	amino acid
CSB68_3860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSB68_3861	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSB68_3864	COG2226	methyltransferase
CSB68_3874	COG0070	glutamate synthase
CSB68_3874	COG0069	glutamate synthase activity
CSB68_3874	COG0067	glutamate synthase
CSB68_3875	COG0493	'glutamate synthase
CSB68_3877	COG1704	LemA family
CSB68_3878	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CSB68_3881	COG3307	-O-antigen
CSB68_3885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSB68_3887	COG0194	GDP metabolic process
CSB68_3897	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CSB68_3901	COG5380	lipid catabolic process
CSB68_3902	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CSB68_3907	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSB68_3908	COG0277	FAD linked oxidase domain protein
CSB68_3910	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CSB68_3911	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB68_3915	COG1289	transmembrane transporter activity
CSB68_3917	COG0628	permease
CSB68_3918	COG1192	Involved in chromosome partitioning
CSB68_3924	COG0833	amino acid
CSB68_3926	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSB68_3927	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSB68_3929	COG1012	belongs to the aldehyde dehydrogenase family
CSB68_3937	COG0583	DNA-binding transcription factor activity
CSB68_3947	COG0517	IMP dehydrogenase activity
CSB68_3948	COG1983	PspC domain protein
CSB68_3950	COG1960	acyl-CoA dehydrogenase activity
CSB68_3953	COG0408	coproporphyrinogen oxidase activity
CSB68_3957	COG0513	Belongs to the DEAD box helicase family
CSB68_3959	COG1127	ABC transporter
CSB68_3960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSB68_3962	COG2854	intermembrane phospholipid transfer
CSB68_3964	COG0598	Magnesium transport protein CorA
CSB68_3966	COG0494	nUDIX hydrolase
CSB68_3967	COG1040	competence protein
CSB68_3968	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSB68_3972	COG1946	Acyl-CoA thioesterase
CSB68_3973	COG1301	dicarboxylic acid transport
CSB68_3976	COG1959	2 iron, 2 sulfur cluster binding
CSB68_3977	COG1017	nitric oxide dioxygenase activity
CSB68_3977	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB68_3978	COG0433	COG0433 Predicted ATPase
CSB68_3979	COG0626	cystathionine gamma-synthase activity
CSB68_4003	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CSB68_4005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CSB68_4010	COG1960	acyl-CoA dehydrogenase activity
CSB68_4011	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CSB68_4016	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSB68_4019	COG1388	LysM domain
CSB68_4037	COG4993	Dehydrogenase
CSB68_4054	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB68_4055	COG3657	addiction module killer protein
CSB68_4059	COG3321	synthase
CSB68_4059	COG0604	alcohol dehydrogenase
CSB68_4060	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CSB68_4061	COG0583	DNA-binding transcription factor activity
CSB68_4062	COG4221	oxidoreductase activity
CSB68_4068	COG3328	transposase activity
CSB68_4069	COG3328	transposase activity
CSB68_4076	COG1063	alcohol dehydrogenase
CSB68_4080	COG4372	Transposase
CSB68_4082	COG3316	Transposase and inactivated derivatives
CSB68_4083	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB68_4083	COG0475	glutathione-regulated potassium exporter activity
CSB68_4089	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CSB68_4091	COG1979	alcohol dehydrogenase
CSB68_4093	COG1902	pentaerythritol trinitrate reductase activity
CSB68_4095	COG1309	transcriptional regulator
CSB68_4096	COG2130	NADP-dependent
CSB68_4099	COG0582	viral genome integration into host DNA
CSB68_4100	COG3328	transposase activity
CSB68_4109	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSB68_4114	COG0194	GDP metabolic process
CSB68_4121	COG0358	DNA primase activity
CSB68_4130	COG3328	transposase activity
CSB68_4163	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CSB68_4168	COG2026	Addiction module toxin, RelE StbE family
CSB68_4172	COG1192	Involved in chromosome partitioning
CSB68_4174	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CSB68_4182	COG4644	lycopene metabolic process
CSB68_4193	COG3316	Transposase and inactivated derivatives
CSB68_4209	COG1192	Involved in chromosome partitioning
CSB68_4211	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CSB68_4215	COG1846	Transcriptional regulator
CSB68_4216	COG1764	response to oxidative stress
CSB68_4223	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB68_4224	COG1764	response to oxidative stress
CSB68_4225	COG1846	Transcriptional regulator
CSB68_4231	COG1846	Transcriptional regulator
CSB68_4232	COG1764	response to oxidative stress
CSB68_4239	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB68_4240	COG1764	response to oxidative stress
CSB68_4241	COG1846	Transcriptional regulator
CSB68_4247	COG1846	Transcriptional regulator
CSB68_4248	COG1764	response to oxidative stress
CSB68_4255	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB68_4256	COG1764	response to oxidative stress
CSB68_4257	COG1846	Transcriptional regulator
CSB68_4265	COG1846	Transcriptional regulator
CSB68_4266	COG1764	response to oxidative stress
CSB68_4267	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB68_4274	COG1764	response to oxidative stress
CSB68_4275	COG1846	Transcriptional regulator