locus-tag	class	description
CSB70_0020	COG0596	Alpha beta hydrolase
CSB70_0021	COG2056	Na+-H+ antiporter family
CSB70_0024	COG0326	Molecular chaperone. Has ATPase activity
CSB70_0027	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSB70_0039	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSB70_0040	COG2169	Transcriptional regulator
CSB70_0040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSB70_0046	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CSB70_0048	COG0497	DNA recombination
CSB70_0051	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSB70_0053	COG0237	dephospho-CoA kinase activity
CSB70_0063	COG0195	Participates in both transcription termination and antitermination
CSB70_0067	COG2212	antiporter activity
CSB70_0069	COG0651	ATP synthesis coupled electron transport
CSB70_0070	COG1006	Multisubunit Na H antiporter MnhC subunit
CSB70_0071	COG2111	Na H antiporter
CSB70_0071	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSB70_0074	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CSB70_0075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_0078	COG2226	methyltransferase
CSB70_0082	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CSB70_0083	COG1074	ATP-dependent DNA helicase activity
CSB70_0084	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB70_0088	COG0598	Magnesium transport protein CorA
CSB70_0089	COG0789	Transcriptional regulator
CSB70_0090	COG0484	heat shock protein binding
CSB70_0093	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB70_0093	COG0475	glutathione-regulated potassium exporter activity
CSB70_0094	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSB70_0098	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB70_0100	COG4535	Mg2 and Co2 transporter CorC
CSB70_0101	COG0425	Belongs to the sulfur carrier protein TusA family
CSB70_0103	COG0644	oxidoreductase
CSB70_0103	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CSB70_0105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CSB70_0109	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_0110	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CSB70_0117	COG4372	Transposase
CSB70_0120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CSB70_0123	COG0534	Mate efflux family protein
CSB70_0125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSB70_0126	COG4221	oxidoreductase activity
CSB70_0127	COG0583	DNA-binding transcription factor activity
CSB70_0131	COG1530	ribonuclease E activity
CSB70_0134	COG0546	phosphoglycolate phosphatase activity
CSB70_0135	COG2378	regulation of single-species biofilm formation
CSB70_0136	COG0625	glutathione transferase activity
CSB70_0138	COG0583	DNA-binding transcription factor activity
CSB70_0147	COG0583	DNA-binding transcription factor activity
CSB70_0152	COG0473	3-isopropylmalate dehydrogenase activity
CSB70_0163	COG1301	dicarboxylic acid transport
CSB70_0165	COG1560	Kdo2-lipid A biosynthetic process
CSB70_0166	COG1280	lysine exporter protein (LysE YggA)
CSB70_0170	COG1733	regulation of RNA biosynthetic process
CSB70_0175	COG0210	DNA helicase
CSB70_0176	COG0724	RNA recognition motif
CSB70_0180	COG4651	solute:proton antiporter activity
CSB70_0180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB70_0181	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSB70_0182	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CSB70_0185	COG0788	formyltetrahydrofolate deformylase activity
CSB70_0208	COG2813	Specifically methylates the guanine in position
CSB70_0208	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB70_0210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSB70_0212	COG4774	siderophore transport
CSB70_0214	COG0740	serine-type endopeptidase activity
CSB70_0220	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CSB70_0220	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CSB70_0221	COG0280	phosphate acetyltransferase
CSB70_0221	COG0857	belongs to the CobB CobQ family
CSB70_0222	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSB70_0224	COG0800	Aldolase
CSB70_0226	COG3265	gluconokinase activity
CSB70_0227	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_0230	COG2267	carboxylic ester hydrolase activity
CSB70_0233	COG0793	Belongs to the peptidase S41A family
CSB70_0240	COG1426	Protein conserved in bacteria
CSB70_0248	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSB70_0250	COG1162	GTPase activity
CSB70_0251	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CSB70_0254	COG1538	Outer membrane efflux protein
CSB70_0255	COG1136	(ABC) transporter
CSB70_0255	COG0577	efflux transmembrane transporter activity
CSB70_0256	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_0261	COG0028	Belongs to the TPP enzyme family
CSB70_0262	COG0440	acetolactate synthase activity
CSB70_0268	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CSB70_0271	COG0084	hydrolase, TatD family'
CSB70_0273	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSB70_0275	COG0583	DNA-binding transcription factor activity
CSB70_0277	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSB70_0278	COG2814	Major facilitator Superfamily
CSB70_0280	COG0697	spore germination
CSB70_0281	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CSB70_0282	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CSB70_0283	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CSB70_0286	COG3622	Belongs to the hyi family
CSB70_0287	COG2084	Dehydrogenase
CSB70_0288	COG1024	Enoyl-CoA hydratase
CSB70_0289	COG5002	protein histidine kinase activity
CSB70_0289	COG0784	Response regulator, receiver
CSB70_0289	COG2205	protein histidine kinase activity
CSB70_0293	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSB70_0295	COG3956	TIGRFAM MazG family protein
CSB70_0296	COG1555	photosystem II stabilization
CSB70_0297	COG0617	tRNA 3'-terminal CCA addition
CSB70_0298	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSB70_0302	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSB70_0303	COG3028	Belongs to the UPF0307 family
CSB70_0304	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_0307	COG0625	glutathione transferase activity
CSB70_0308	COG1238	metal cluster binding
CSB70_0311	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CSB70_0316	COG0072	phenylalanine-tRNA ligase activity
CSB70_0322	COG0248	Ppx GppA phosphatase
CSB70_0324	COG0037	tRNA processing
CSB70_0332	COG1764	response to oxidative stress
CSB70_0333	COG1846	Transcriptional regulator
CSB70_0335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSB70_0347	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CSB70_0348	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CSB70_0349	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CSB70_0351	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSB70_0361	COG1214	PFAM Peptidase M22, glycoprotease
CSB70_0364	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CSB70_0368	COG4372	Transposase
CSB70_0369	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSB70_0370	COG0561	phosphatase activity
CSB70_0372	COG2132	Multicopper oxidase
CSB70_0373	COG3667	copper resistance
CSB70_0376	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSB70_0377	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CSB70_0378	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CSB70_0384	COG1063	alcohol dehydrogenase
CSB70_0385	COG0583	DNA-binding transcription factor activity
CSB70_0387	COG1960	acyl-CoA dehydrogenase activity
CSB70_0388	COG2814	Major facilitator Superfamily
CSB70_0389	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSB70_0391	COG1053	succinate dehydrogenase
CSB70_0392	COG0583	DNA-binding transcription factor activity
CSB70_0395	COG0583	DNA-binding transcription factor activity
CSB70_0397	COG1473	amidohydrolase
CSB70_0401	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CSB70_0402	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_0410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSB70_0413	COG0745	RESPONSE REGULATOR receiver
CSB70_0414	COG2205	protein histidine kinase activity
CSB70_0416	COG3706	GGDEF domain
CSB70_0417	COG4372	Transposase
CSB70_0424	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CSB70_0430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSB70_0431	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSB70_0436	COG0583	DNA-binding transcription factor activity
CSB70_0440	COG0668	transmembrane transport
CSB70_0442	COG2081	HI0933 family
CSB70_0443	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CSB70_0449	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB70_0449	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB70_0451	COG0489	protein tyrosine kinase activity
CSB70_0462	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSB70_0464	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSB70_0467	COG0730	response to heat
CSB70_0469	COG1196	nuclear chromosome segregation
CSB70_0473	COG2223	nitrite transmembrane transporter activity
CSB70_0474	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CSB70_0475	COG1877	trehalose-phosphatase activity
CSB70_0476	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB70_0476	COG0596	Alpha beta hydrolase
CSB70_0476	COG2226	methyltransferase
CSB70_0479	COG4106	trans-aconitate 2-methyltransferase activity
CSB70_0482	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CSB70_0483	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CSB70_0484	COG0009	L-threonylcarbamoyladenylate synthase
CSB70_0485	COG3101	peptidyl-lysine hydroxylation
CSB70_0486	COG1399	metal-binding, possibly nucleic acid-binding protein
CSB70_0491	COG1652	LysM domain
CSB70_0492	COG0351	phosphomethylpyrimidine kinase
CSB70_0492	COG0352	thiamine-phosphate diphosphorylase activity
CSB70_0492	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSB70_0494	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSB70_0500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSB70_0505	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CSB70_0508	COG0358	DNA primase activity
CSB70_0510	COG0564	pseudouridine synthase activity
CSB70_0515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSB70_0518	COG0583	DNA-binding transcription factor activity
CSB70_0519	COG0473	3-isopropylmalate dehydrogenase activity
CSB70_0523	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_0527	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CSB70_0527	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSB70_0539	COG0456	acetyltransferase
CSB70_0541	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CSB70_0542	COG0492	ferredoxin-NADP+ reductase activity
CSB70_0543	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CSB70_0543	COG1674	ftsk spoiiie
CSB70_0544	COG1280	lysine exporter protein (LysE YggA)
CSB70_0547	COG2894	cell division
CSB70_0550	COG0204	Acyl-transferase
CSB70_0551	COG2885	chlorophyll binding
CSB70_0552	COG0210	DNA helicase
CSB70_0554	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSB70_0557	COG0121	glutamine amidotransferase
CSB70_0561	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSB70_0562	COG0735	belongs to the Fur family
CSB70_0567	COG0420	3'-5' exonuclease activity
CSB70_0571	COG1090	epimerase
CSB70_0574	COG2050	protein possibly involved in aromatic compounds catabolism
CSB70_0576	COG2814	Major facilitator Superfamily
CSB70_0577	COG0405	Gamma-glutamyltransferase
CSB70_0580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CSB70_0581	COG0732	type I restriction modification DNA specificity domain
CSB70_0582	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CSB70_0583	COG4372	Transposase
CSB70_0590	COG4372	Transposase
CSB70_0610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CSB70_0612	COG0402	S-adenosylhomocysteine deaminase activity
CSB70_0616	COG1053	succinate dehydrogenase
CSB70_0625	COG0583	DNA-binding transcription factor activity
CSB70_0635	COG0477	Major facilitator Superfamily
CSB70_0636	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB70_0642	COG0531	amino acid
CSB70_0643	COG2040	homocysteine
CSB70_0648	COG1309	transcriptional regulator
CSB70_0649	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB70_0650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB70_0652	COG1607	acyl-coa hydrolase
CSB70_0654	COG0523	cobalamin synthesis protein
CSB70_0656	COG4681	YaeQ
CSB70_0658	COG0726	polysaccharide deacetylase
CSB70_0658	COG1649	PFAM Uncharacterised BCR, COG1649
CSB70_0659	COG1215	transferase activity, transferring glycosyl groups
CSB70_0661	COG1024	Enoyl-CoA hydratase
CSB70_0664	COG1414	Transcriptional regulator
CSB70_0667	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_0670	COG2271	Major facilitator Superfamily
CSB70_0672	COG2267	carboxylic ester hydrolase activity
CSB70_0673	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_0675	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_0676	COG0028	Belongs to the TPP enzyme family
CSB70_0678	COG0477	Major facilitator Superfamily
CSB70_0680	COG0242	peptide deformylase activity
CSB70_0681	COG2066	Belongs to the glutaminase family
CSB70_0682	COG2207	Transcriptional regulator
CSB70_0683	COG2223	nitrite transmembrane transporter activity
CSB70_0686	COG0583	DNA-binding transcription factor activity
CSB70_0687	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_0688	COG2271	Major facilitator Superfamily
CSB70_0689	COG3959	Transketolase, thiamine diphosphate binding domain
CSB70_0690	COG3958	Transketolase
CSB70_0693	COG0306	phosphate transporter
CSB70_0698	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSB70_0708	COG4181	ATPase activity
CSB70_0709	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CSB70_0714	COG0583	DNA-binding transcription factor activity
CSB70_0716	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB70_0717	COG1773	rubredoxin
CSB70_0726	COG2851	Citrate transporter
CSB70_0727	COG1253	flavin adenine dinucleotide binding
CSB70_0736	COG0804	urea catabolic process
CSB70_0738	COG0830	nickel cation binding
CSB70_0741	COG0742	ribosomal rna small subunit methyltransferase
CSB70_0742	COG0768	penicillin binding
CSB70_0747	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSB70_0748	COG2878	Part of a membrane complex involved in electron transport
CSB70_0749	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSB70_0751	COG3384	dioxygenase
CSB70_0754	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSB70_0819	COG1278	Cold shock
CSB70_0826	COG0006	proline dipeptidase activity
CSB70_0827	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_0828	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_0832	COG1279	arginine transmembrane transporter activity
CSB70_0833	COG0583	DNA-binding transcription factor activity
CSB70_0841	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB70_0842	COG1388	LysM domain
CSB70_0842	COG0741	lytic transglycosylase activity
CSB70_0842	COG0741	lytic transglycosylase activity
CSB70_0842	COG1388	LysM domain
CSB70_0844	COG4174	ABC transporter (Permease)
CSB70_0845	COG4239	(ABC) transporter, permease
CSB70_0846	COG4172	Belongs to the ABC transporter superfamily
CSB70_0850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB70_0852	COG2203	Gaf domain
CSB70_0852	COG3706	GGDEF domain
CSB70_0852	COG4251	negative regulation of phosphorylation
CSB70_0852	COG5001	Diguanylate cyclase
CSB70_0854	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB70_0854	COG1902	pentaerythritol trinitrate reductase activity
CSB70_0857	COG4269	membrane
CSB70_0862	COG3501	Rhs element vgr protein
CSB70_0863	COG3209	COG3209 Rhs family protein
CSB70_0868	COG1113	amino acid transport
CSB70_0870	COG0531	amino acid
CSB70_0874	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_0878	COG1113	amino acid transport
CSB70_0886	COG0697	spore germination
CSB70_0887	COG2721	sulfolactate sulfo-lyase activity
CSB70_0888	COG2271	Major facilitator Superfamily
CSB70_0889	COG4948	Mandelate Racemase Muconate Lactonizing
CSB70_0891	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_0892	COG2186	Transcriptional regulator
CSB70_0897	COG1960	acyl-CoA dehydrogenase activity
CSB70_0899	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_0900	COG1024	Enoyl-CoA hydratase
CSB70_0901	COG2814	Major facilitator Superfamily
CSB70_0904	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_0907	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSB70_0916	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CSB70_0917	COG2072	flavoprotein involved in K transport
CSB70_0918	COG0300	oxidoreductase activity
CSB70_0920	COG1309	transcriptional regulator
CSB70_0921	COG1741	Belongs to the pirin family
CSB70_0924	COG2072	flavoprotein involved in K transport
CSB70_0926	COG2252	PERMEase
CSB70_0927	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CSB70_0928	COG3038	cytochrome b561
CSB70_0930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CSB70_0934	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSB70_0938	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CSB70_0941	COG0667	Aldo Keto reductase
CSB70_0942	COG0667	Aldo Keto reductase
CSB70_0944	COG1765	OsmC-like protein
CSB70_0954	COG2885	chlorophyll binding
CSB70_0956	COG0625	glutathione transferase activity
CSB70_0957	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSB70_0961	COG3634	alkyl hydroperoxide reductase activity
CSB70_0963	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CSB70_0965	COG0450	alkyl hydroperoxide reductase
CSB70_0966	COG1643	Atp-dependent helicase
CSB70_0969	COG2814	Major facilitator Superfamily
CSB70_0970	COG3135	benzoate transporter
CSB70_0971	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_0972	COG0633	Ferredoxin
CSB70_0972	COG0543	2 iron, 2 sulfur cluster binding
CSB70_0973	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CSB70_0974	COG4638	Rieske (2fe-2S)
CSB70_0976	COG0583	DNA-binding transcription factor activity
CSB70_0978	COG2871	sodium ion transport
CSB70_0995	COG1570	exodeoxyribonuclease VII activity
CSB70_1001	COG1280	lysine exporter protein (LysE YggA)
CSB70_1002	COG1278	Cold shock
CSB70_1009	COG2814	Major facilitator Superfamily
CSB70_1010	COG1733	regulation of RNA biosynthetic process
CSB70_1036	COG5484	DNA packaging
CSB70_1036	COG3728	DNA packaging
CSB70_1066	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CSB70_1068	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CSB70_1069	COG1137	ATPase activity
CSB70_1070	COG1538	Outer membrane efflux protein
CSB70_1078	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CSB70_1081	COG1522	sequence-specific DNA binding
CSB70_1082	COG5006	permease, DMT superfamily
CSB70_1084	COG1560	Kdo2-lipid A biosynthetic process
CSB70_1086	COG2814	Major facilitator Superfamily
CSB70_1091	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB70_1096	COG3501	Rhs element vgr protein
CSB70_1097	COG3209	COG3209 Rhs family protein
CSB70_1102	COG0583	DNA-binding transcription factor activity
CSB70_1103	COG1914	H( )-stimulated, divalent metal cation uptake system
CSB70_1107	COG4770	biotin carboxylase activity
CSB70_1108	COG0038	chloride channel
CSB70_1115	COG4372	Transposase
CSB70_1119	COG1309	transcriptional regulator
CSB70_1121	COG1063	alcohol dehydrogenase
CSB70_1124	COG0439	Biotin carboxylase
CSB70_1125	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_1126	COG1733	regulation of RNA biosynthetic process
CSB70_1128	COG0864	Transcriptional regulator
CSB70_1130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB70_1131	COG1116	anion transmembrane transporter activity
CSB70_1146	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CSB70_1146	COG2885	chlorophyll binding
CSB70_1154	COG0583	DNA-binding transcription factor activity
CSB70_1156	COG0590	tRNA wobble adenosine to inosine editing
CSB70_1157	COG2807	transmembrane transport
CSB70_1160	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSB70_1161	COG0789	Transcriptional regulator
CSB70_1163	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB70_1167	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSB70_1172	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_1173	COG0531	amino acid
CSB70_1174	COG1760	l-serine dehydratase
CSB70_1175	COG2030	dehydratase
CSB70_1175	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_1176	COG3396	Phenylacetate-CoA oxygenase
CSB70_1177	COG3460	Phenylacetate-CoA oxygenase
CSB70_1178	COG3396	Phenylacetate-CoA oxygenase
CSB70_1179	COG2151	metal-sulfur cluster biosynthetic enzyme
CSB70_1180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_1181	COG1024	Enoyl-CoA hydratase
CSB70_1182	COG1024	Enoyl-CoA hydratase
CSB70_1183	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB70_1184	COG0183	Belongs to the thiolase family
CSB70_1185	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CSB70_1186	COG3327	negative regulation of DNA-templated transcription, initiation
CSB70_1188	COG2050	protein possibly involved in aromatic compounds catabolism
CSB70_1196	COG1278	Cold shock
CSB70_1198	COG2207	Transcriptional regulator
CSB70_1201	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSB70_1202	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSB70_1203	COG2271	Major facilitator Superfamily
CSB70_1204	COG0753	catalase activity
CSB70_1205	COG3038	cytochrome b561
CSB70_1206	COG0583	DNA-binding transcription factor activity
CSB70_1208	COG1414	Transcriptional regulator
CSB70_1209	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_1211	COG1840	ABC-type Fe3 transport system, periplasmic component
CSB70_1212	COG3842	ATPase activity
CSB70_1215	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSB70_1216	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSB70_1217	COG2814	Major facilitator Superfamily
CSB70_1218	COG1960	acyl-CoA dehydrogenase activity
CSB70_1221	COG1024	Enoyl-CoA hydratase
CSB70_1223	COG2814	Major facilitator Superfamily
CSB70_1225	COG0183	Belongs to the thiolase family
CSB70_1226	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB70_1227	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1228	COG1024	Enoyl-CoA hydratase
CSB70_1229	COG1960	acyl-CoA dehydrogenase activity
CSB70_1230	COG2814	Major facilitator Superfamily
CSB70_1231	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB70_1232	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB70_1234	COG2814	Major facilitator Superfamily
CSB70_1236	COG1960	acyl-CoA dehydrogenase activity
CSB70_1239	COG0583	DNA-binding transcription factor activity
CSB70_1242	COG1024	Enoyl-CoA hydratase
CSB70_1243	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSB70_1244	COG1960	acyl-CoA dehydrogenase activity
CSB70_1245	COG1309	transcriptional regulator
CSB70_1246	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_1250	COG0583	DNA-binding transcription factor activity
CSB70_1252	COG4372	Transposase
CSB70_1263	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1267	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSB70_1271	COG2205	protein histidine kinase activity
CSB70_1271	COG0784	Response regulator, receiver
CSB70_1275	COG0765	amino acid transport
CSB70_1276	COG0765	amino acid transport
CSB70_1277	COG1126	abc transporter atp-binding protein
CSB70_1278	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB70_1279	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB70_1282	COG1280	lysine exporter protein (LysE YggA)
CSB70_1283	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSB70_1284	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSB70_1285	COG1045	serine acetyltransferase
CSB70_1288	COG0583	DNA-binding transcription factor activity
CSB70_1289	COG0625	glutathione transferase activity
CSB70_1290	COG0625	glutathione transferase activity
CSB70_1291	COG0583	DNA-binding transcription factor activity
CSB70_1293	COG1346	cytolysis
CSB70_1294	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_1297	COG2814	Major facilitator Superfamily
CSB70_1299	COG0583	DNA-binding transcription factor activity
CSB70_1301	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CSB70_1302	COG3052	prosthetic group binding
CSB70_1306	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSB70_1310	COG4372	Transposase
CSB70_1314	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_1316	COG1294	oxidase, subunit
CSB70_1317	COG1271	oxidase subunit
CSB70_1322	COG0477	Major facilitator Superfamily
CSB70_1324	COG4521	taurine ABC transporter
CSB70_1325	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CSB70_1326	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB70_1327	COG2175	clavaminate synthase activity
CSB70_1329	COG1953	Uracil, thiamine, allantoin
CSB70_1331	COG0583	DNA-binding transcription factor activity
CSB70_1333	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CSB70_1336	COG0640	Transcriptional regulator
CSB70_1337	COG0798	PFAM Bile acid sodium symporter
CSB70_1338	COG0583	DNA-binding transcription factor activity
CSB70_1341	COG3634	alkyl hydroperoxide reductase activity
CSB70_1349	COG0436	Aminotransferase
CSB70_1351	COG0386	Belongs to the glutathione peroxidase family
CSB70_1359	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CSB70_1364	COG0012	GTP binding
CSB70_1365	COG2011	ABC-type metal ion transport system permease component
CSB70_1366	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSB70_1368	COG1464	Belongs to the NlpA lipoprotein family
CSB70_1374	COG0765	amino acid transport
CSB70_1375	COG0765	amino acid transport
CSB70_1376	COG1126	abc transporter atp-binding protein
CSB70_1378	COG1522	sequence-specific DNA binding
CSB70_1394	COG0305	Participates in initiation and elongation during chromosome replication
CSB70_1422	COG0739	heme binding
CSB70_1422	COG0741	lytic transglycosylase activity
CSB70_1422	COG1196	nuclear chromosome segregation
CSB70_1438	COG1309	transcriptional regulator
CSB70_1443	COG0583	DNA-binding transcription factor activity
CSB70_1445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CSB70_1447	COG0697	spore germination
CSB70_1455	COG3121	Chaperone
CSB70_1456	COG3539	Fimbrial protein
CSB70_1462	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSB70_1462	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSB70_1473	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSB70_1475	COG2353	YceI-like domain
CSB70_1477	COG3698	Phosphodiester glycosidase
CSB70_1480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSB70_1481	COG0506	proline dehydrogenase activity
CSB70_1481	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CSB70_1481	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CSB70_1484	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSB70_1485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CSB70_1489	COG1132	(ABC) transporter
CSB70_1490	COG3122	Protein conserved in bacteria
CSB70_1491	COG3619	membrane
CSB70_1493	COG0640	Transcriptional regulator
CSB70_1495	COG2850	peptidyl-arginine hydroxylation
CSB70_1496	COG0424	maF-like protein
CSB70_1500	COG0191	fructose-bisphosphate aldolase activity
CSB70_1501	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSB70_1504	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSB70_1506	COG1192	Involved in chromosome partitioning
CSB70_1507	COG1475	DNA binding
CSB70_1508	COG0811	peptide transport
CSB70_1510	COG1132	(ABC) transporter
CSB70_1511	COG1663	tetraacyldisaccharide 4'-kinase activity
CSB70_1515	COG0084	hydrolase, TatD family'
CSB70_1518	COG2165	general secretion pathway protein
CSB70_1524	COG0590	tRNA wobble adenosine to inosine editing
CSB70_1528	COG0776	regulation of translation
CSB70_1534	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CSB70_1547	COG0305	Participates in initiation and elongation during chromosome replication
CSB70_1569	COG3646	Phage regulatory protein
CSB70_1577	COG4372	Transposase
CSB70_1578	COG0739	heme binding
CSB70_1578	COG0741	lytic transglycosylase activity
CSB70_1578	COG1196	nuclear chromosome segregation
CSB70_1590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CSB70_1597	COG4166	transmembrane transport
CSB70_1599	COG0339	signal peptide processing
CSB70_1601	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSB70_1608	COG0702	epimerase
CSB70_1609	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSB70_1613	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSB70_1619	COG0316	Belongs to the HesB IscA family
CSB70_1620	COG0822	iron-sulfur transferase activity
CSB70_1625	COG0776	regulation of translation
CSB70_1626	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSB70_1627	COG2207	Transcriptional regulator
CSB70_1628	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSB70_1629	COG1960	acyl-CoA dehydrogenase activity
CSB70_1630	COG1960	acyl-CoA dehydrogenase activity
CSB70_1633	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSB70_1636	COG2814	Major facilitator Superfamily
CSB70_1637	COG4264	IucA IucC family
CSB70_1638	COG4264	IucA IucC family
CSB70_1640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSB70_1651	COG0406	alpha-ribazole phosphatase activity
CSB70_1654	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSB70_1655	COG0730	response to heat
CSB70_1659	COG4773	Receptor
CSB70_1660	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB70_1663	COG1131	(ABC) transporter
CSB70_1664	COG0842	Transport permease protein
CSB70_1665	COG0842	Transport permease protein
CSB70_1666	COG0842	Transport permease protein
CSB70_1677	COG2226	methyltransferase
CSB70_1683	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CSB70_1690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSB70_1692	COG0133	tryptophan synthase activity
CSB70_1695	COG3706	GGDEF domain
CSB70_1698	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CSB70_1699	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSB70_1700	COG0022	dehydrogenase e1 component
CSB70_1701	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSB70_1702	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB70_1704	COG1063	alcohol dehydrogenase
CSB70_1705	COG3781	membrane
CSB70_1707	COG3453	Protein conserved in bacteria
CSB70_1707	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_1709	COG0730	response to heat
CSB70_1712	COG3708	Transcriptional regulator
CSB70_1712	COG2207	Transcriptional regulator
CSB70_1713	COG1733	regulation of RNA biosynthetic process
CSB70_1714	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CSB70_1719	COG4521	taurine ABC transporter
CSB70_1720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB70_1724	COG0477	Major facilitator Superfamily
CSB70_1726	COG1027	Aspartate ammonia-lyase
CSB70_1729	COG0583	DNA-binding transcription factor activity
CSB70_1730	COG0583	DNA-binding transcription factor activity
CSB70_1731	COG0183	Belongs to the thiolase family
CSB70_1732	COG2031	fatty acid transporter
CSB70_1735	COG0583	DNA-binding transcription factor activity
CSB70_1743	COG2610	gluconate transmembrane transporter activity
CSB70_1744	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1745	COG2207	Transcriptional regulator
CSB70_1747	COG0412	Dienelactone hydrolase
CSB70_1748	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_1753	COG0543	2 iron, 2 sulfur cluster binding
CSB70_1753	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_1754	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CSB70_1755	COG4638	Rieske (2fe-2S)
CSB70_1757	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSB70_1758	COG4149	molybdate abc transporter
CSB70_1759	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSB70_1760	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1761	COG3433	isochorismatase activity
CSB70_1761	COG1535	isochorismatase
CSB70_1774	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSB70_1795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSB70_1796	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_1797	COG0745	RESPONSE REGULATOR receiver
CSB70_1798	COG2205	protein histidine kinase activity
CSB70_1800	COG2207	Transcriptional regulator
CSB70_1803	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1816	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CSB70_1833	COG4372	Transposase
CSB70_1840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSB70_1844	COG1120	ATPase activity
CSB70_1848	COG1064	alcohol dehydrogenase
CSB70_1849	COG2207	Transcriptional regulator
CSB70_1850	COG2084	Dehydrogenase
CSB70_1852	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSB70_1855	COG0583	DNA-binding transcription factor activity
CSB70_1857	COG0129	dihydroxy-acid dehydratase activity
CSB70_1858	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_1861	COG1566	PFAM secretion protein HlyD family protein
CSB70_1864	COG0583	DNA-binding transcription factor activity
CSB70_1879	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_1881	COG1960	acyl-CoA dehydrogenase activity
CSB70_1883	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1884	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1885	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1886	COG0583	DNA-binding transcription factor activity
CSB70_1887	COG1309	transcriptional regulator
CSB70_1892	COG0789	Transcriptional regulator
CSB70_1895	COG1902	pentaerythritol trinitrate reductase activity
CSB70_1895	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB70_1898	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_1902	COG2186	Transcriptional regulator
CSB70_1904	COG0583	DNA-binding transcription factor activity
CSB70_1905	COG4948	Mandelate Racemase Muconate Lactonizing
CSB70_1906	COG4829	muconolactone delta-isomerase
CSB70_1908	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB70_1909	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB70_1910	COG0183	Belongs to the thiolase family
CSB70_1911	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB70_1913	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_1915	COG3733	amine oxidase
CSB70_1917	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_1919	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_1921	COG4638	Rieske (2fe-2S)
CSB70_1925	COG0154	amidase activity
CSB70_1928	COG2814	Major facilitator Superfamily
CSB70_1933	COG1960	acyl-CoA dehydrogenase activity
CSB70_1934	COG0583	DNA-binding transcription factor activity
CSB70_1935	COG1414	Transcriptional regulator
CSB70_1938	COG2391	methyltransferase activity
CSB70_1940	COG4993	Dehydrogenase
CSB70_1941	COG3659	wide pore channel activity
CSB70_1942	COG3420	alginic acid biosynthetic process
CSB70_1943	COG0710	3-dehydroquinate dehydratase activity
CSB70_1944	COG3485	protocatechuate 3,4-dioxygenase
CSB70_1945	COG3485	protocatechuate 3,4-dioxygenase
CSB70_1946	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSB70_1947	COG2271	Major facilitator Superfamily
CSB70_1948	COG0596	Alpha beta hydrolase
CSB70_1949	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSB70_1950	COG0183	Belongs to the thiolase family
CSB70_1951	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB70_1952	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB70_1954	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CSB70_1955	COG2323	membrane
CSB70_1964	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB70_1964	COG1902	pentaerythritol trinitrate reductase activity
CSB70_1967	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSB70_1969	COG0542	response to heat
CSB70_1970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CSB70_1977	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSB70_1978	COG0569	domain protein
CSB70_1979	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSB70_1982	COG4774	siderophore transport
CSB70_1983	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSB70_1985	COG1585	Membrane protein implicated in regulation of membrane protease activity
CSB70_1988	COG1294	oxidase, subunit
CSB70_1992	COG4372	Transposase
CSB70_1993	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CSB70_1995	COG0552	protein localization to endoplasmic reticulum
CSB70_2000	COG0517	IMP dehydrogenase activity
CSB70_2000	COG0516	GMP reductase activity
CSB70_2001	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSB70_2002	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CSB70_2004	COG0583	DNA-binding transcription factor activity
CSB70_2005	COG0024	Methionine aminopeptidase
CSB70_2010	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSB70_2010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CSB70_2011	COG1105	Belongs to the carbohydrate kinase PfkB family
CSB70_2012	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSB70_2012	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSB70_2012	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CSB70_2016	COG3300	MHYT domain
CSB70_2016	COG5001	Diguanylate cyclase
CSB70_2021	COG2135	peptidase activity
CSB70_2022	COG0659	secondary active sulfate transmembrane transporter activity
CSB70_2025	COG1113	amino acid transport
CSB70_2027	COG1522	sequence-specific DNA binding
CSB70_2032	COG1011	Hydrolase
CSB70_2033	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSB70_2035	COG2137	regulation of response to DNA damage stimulus
CSB70_2037	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB70_2041	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSB70_2044	COG0575	Belongs to the CDS family
CSB70_2045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CSB70_2050	COG3852	Histidine kinase
CSB70_2051	COG2204	response regulator
CSB70_2063	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSB70_2064	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CSB70_2068	COG0697	spore germination
CSB70_2069	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_2071	COG0303	'Molybdopterin
CSB70_2072	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSB70_2072	COG0315	cyclic pyranopterin monophosphate synthase activity
CSB70_2075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSB70_2076	COG0243	molybdopterin cofactor binding
CSB70_2078	COG0243	molybdopterin cofactor binding
CSB70_2079	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB70_2080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB70_2080	COG2146	nitrite reductase [NAD(P)H] activity
CSB70_2082	COG0745	RESPONSE REGULATOR receiver
CSB70_2083	COG1116	anion transmembrane transporter activity
CSB70_2083	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB70_2086	COG0511	ligase activity, forming carbon-carbon bonds
CSB70_2089	COG2814	Major facilitator Superfamily
CSB70_2096	COG0069	glutamate synthase activity
CSB70_2102	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSB70_2104	COG1454	alcohol dehydrogenase
CSB70_2105	COG0824	Thioesterase
CSB70_2108	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSB70_2117	COG0183	Belongs to the thiolase family
CSB70_2119	COG0583	DNA-binding transcription factor activity
CSB70_2122	COG1522	sequence-specific DNA binding
CSB70_2123	COG3135	benzoate transporter
CSB70_2124	COG4372	Transposase
CSB70_2128	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CSB70_2132	COG0589	response to stress
CSB70_2133	COG0488	(ABC) transporter
CSB70_2134	COG0488	(ABC) transporter
CSB70_2139	COG4773	Receptor
CSB70_2144	COG0668	transmembrane transport
CSB70_2146	COG1309	transcriptional regulator
CSB70_2149	COG1605	Chorismate mutase
CSB70_2157	COG0308	aminopeptidase N
CSB70_2161	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CSB70_2163	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB70_2164	COG1454	alcohol dehydrogenase
CSB70_2168	COG0531	amino acid
CSB70_2169	COG4303	Ethanolamine ammonia lyase large subunit
CSB70_2170	COG4302	ethanolamine ammonia-lyase activity
CSB70_2171	COG0519	Catalyzes the synthesis of GMP from XMP
CSB70_2171	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSB70_2174	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB70_2177	COG0697	spore germination
CSB70_2178	COG1923	regulation of RNA biosynthetic process
CSB70_2180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CSB70_2181	COG0802	atpase or kinase
CSB70_2185	COG1187	pseudouridine synthase activity
CSB70_2189	COG0583	DNA-binding transcription factor activity
CSB70_2192	COG2814	Major facilitator Superfamily
CSB70_2193	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSB70_2198	COG0729	surface antigen
CSB70_2199	COG0477	Major facilitator Superfamily
CSB70_2202	COG0174	glutamine synthetase
CSB70_2203	COG0745	RESPONSE REGULATOR receiver
CSB70_2204	COG2205	protein histidine kinase activity
CSB70_2206	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CSB70_2207	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CSB70_2212	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_2213	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB70_2214	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB70_2216	COG1960	acyl-CoA dehydrogenase activity
CSB70_2219	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB70_2220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB70_2223	COG3328	transposase activity
CSB70_2225	COG0583	DNA-binding transcription factor activity
CSB70_2228	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSB70_2230	COG3658	cytochrome
CSB70_2231	COG1215	transferase activity, transferring glycosyl groups
CSB70_2232	COG1649	PFAM Uncharacterised BCR, COG1649
CSB70_2232	COG0726	polysaccharide deacetylase
CSB70_2237	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CSB70_2238	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CSB70_2240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CSB70_2245	COG0305	Participates in initiation and elongation during chromosome replication
CSB70_2246	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSB70_2248	COG1305	Transglutaminase-like
CSB70_2250	COG2308	Evidence 4 Homologs of previously reported genes of
CSB70_2257	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CSB70_2258	COG0138	bifunctional purine biosynthesis protein purh
CSB70_2259	COG0151	Belongs to the GarS family
CSB70_2260	COG1464	Belongs to the NlpA lipoprotein family
CSB70_2261	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSB70_2262	COG2011	ABC-type metal ion transport system permease component
CSB70_2263	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_2265	COG1301	dicarboxylic acid transport
CSB70_2270	COG4372	Transposase
CSB70_2274	COG1794	racemase activity, acting on amino acids and derivatives
CSB70_2278	COG0745	RESPONSE REGULATOR receiver
CSB70_2279	COG0642	Histidine kinase
CSB70_2280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSB70_2282	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSB70_2290	COG2351	hydroxyisourate hydrolase activity
CSB70_2292	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CSB70_2292	COG3008	intermembrane lipid transfer
CSB70_2293	COG2995	paraquat-inducible protein a
CSB70_2296	COG2985	domain, Protein
CSB70_2302	COG1051	belongs to the nudix hydrolase family
CSB70_2303	COG0477	Major facilitator Superfamily
CSB70_2313	COG2186	Transcriptional regulator
CSB70_2315	COG0786	glutamate:sodium symporter activity
CSB70_2316	COG3243	poly(R)-hydroxyalkanoic acid synthase
CSB70_2321	COG3111	PFAM Bacterial OB fold (BOF) protein
CSB70_2332	COG3328	transposase activity
CSB70_2335	COG3210	domain, Protein
CSB70_2336	COG2831	hemolysin activation secretion protein
CSB70_2341	COG0515	serine threonine protein kinase
CSB70_2341	COG2815	serine threonine protein kinase
CSB70_2346	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CSB70_2347	COG1610	YqeY-like protein
CSB70_2348	COG4783	chaperone-mediated protein folding
CSB70_2353	COG1286	toxin biosynthetic process
CSB70_2359	COG0778	Nitroreductase
CSB70_2361	COG0513	Belongs to the DEAD box helicase family
CSB70_2365	COG2363	Small membrane protein
CSB70_2371	COG1234	tRNA 3'-trailer cleavage
CSB70_2372	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSB70_2374	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CSB70_2376	COG2819	hydrolase of the alpha beta superfamily
CSB70_2377	COG1960	acyl-CoA dehydrogenase activity
CSB70_2378	COG1301	dicarboxylic acid transport
CSB70_2379	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSB70_2380	COG3139	Protein of unknown function (DUF1315)
CSB70_2381	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CSB70_2382	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSB70_2384	COG0494	nUDIX hydrolase
CSB70_2386	COG0642	Histidine kinase
CSB70_2387	COG0745	RESPONSE REGULATOR receiver
CSB70_2391	COG1720	tRNA m6t6A37 methyltransferase activity
CSB70_2394	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_2396	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSB70_2398	COG4598	ABC transporter
CSB70_2399	COG4160	amino acid transport
CSB70_2400	COG4215	(ABC) transporter
CSB70_2403	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_2405	COG1538	Outer membrane efflux protein
CSB70_2457	COG0305	Participates in initiation and elongation during chromosome replication
CSB70_2471	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB70_2477	COG0582	viral genome integration into host DNA
CSB70_2478	COG1131	(ABC) transporter
CSB70_2479	COG0842	Transport permease protein
CSB70_2482	COG0772	Belongs to the SEDS family
CSB70_2483	COG2951	lytic endotransglycosylase activity
CSB70_2487	COG2207	Transcriptional regulator
CSB70_2490	COG0052	Belongs to the universal ribosomal protein uS2 family
CSB70_2491	COG0024	Methionine aminopeptidase
CSB70_2494	COG2223	nitrite transmembrane transporter activity
CSB70_2497	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB70_2498	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CSB70_2499	COG1960	acyl-CoA dehydrogenase activity
CSB70_2502	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CSB70_2503	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSB70_2504	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSB70_2508	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSB70_2509	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSB70_2510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSB70_2517	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CSB70_2520	COG3104	oligopeptide transport
CSB70_2522	COG0512	Glutamine amidotransferase of anthranilate synthase
CSB70_2529	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CSB70_2539	COG3739	integral membrane protein
CSB70_2544	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CSB70_2546	COG1132	(ABC) transporter
CSB70_2549	COG3433	isochorismatase activity
CSB70_2549	COG1535	isochorismatase
CSB70_2550	COG1021	2,3-dihydroxybenzoate-AMP ligase
CSB70_2551	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB70_2553	COG4774	siderophore transport
CSB70_2554	COG4607	ABC-type enterochelin transport system periplasmic component
CSB70_2555	COG4604	ABC transporter, ATP-binding protein
CSB70_2556	COG4605	iron ion homeostasis
CSB70_2557	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSB70_2559	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB70_2562	COG2964	Protein conserved in bacteria
CSB70_2564	COG1741	Belongs to the pirin family
CSB70_2571	COG2879	small protein
CSB70_2572	COG1966	Carbon starvation protein
CSB70_2576	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CSB70_2582	COG1067	ATP-dependent peptidase activity
CSB70_2583	COG0583	DNA-binding transcription factor activity
CSB70_2588	COG1686	Belongs to the peptidase S11 family
CSB70_2589	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSB70_2598	COG4372	Transposase
CSB70_2600	COG0616	signal peptide processing
CSB70_2601	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSB70_2603	COG0573	inorganic phosphate transmembrane transporter activity
CSB70_2604	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSB70_2605	COG1113	amino acid transport
CSB70_2606	COG3961	Belongs to the TPP enzyme family
CSB70_2607	COG1522	sequence-specific DNA binding
CSB70_2609	COG0076	glutamate decarboxylase activity
CSB70_2610	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSB70_2613	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_2615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_2623	COG0352	thiamine-phosphate diphosphorylase activity
CSB70_2628	COG0612	Peptidase, M16
CSB70_2631	COG0583	DNA-binding transcription factor activity
CSB70_2632	COG0477	Major facilitator Superfamily
CSB70_2637	COG1187	pseudouridine synthase activity
CSB70_2640	COG1686	Belongs to the peptidase S11 family
CSB70_2641	COG1252	NADH dehydrogenase
CSB70_2643	COG0415	Belongs to the DNA photolyase family
CSB70_2646	COG1215	transferase activity, transferring glycosyl groups
CSB70_2652	COG2070	2-Nitropropane dioxygenase
CSB70_2663	COG0556	nucleotide-excision repair
CSB70_2671	COG0443	Heat shock 70 kDa protein
CSB70_2676	COG4221	oxidoreductase activity
CSB70_2678	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CSB70_2679	COG1381	Involved in DNA repair and RecF pathway recombination
CSB70_2681	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSB70_2684	COG0681	Belongs to the peptidase S26 family
CSB70_2687	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSB70_2691	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CSB70_2692	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSB70_2693	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CSB70_2696	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CSB70_2697	COG4208	sulfate ABC transporter
CSB70_2698	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CSB70_2699	COG0583	DNA-binding transcription factor activity
CSB70_2700	COG4625	pathogenesis
CSB70_2703	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CSB70_2706	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSB70_2708	COG1051	belongs to the nudix hydrolase family
CSB70_2708	COG1056	cytidyltransferase-related domain
CSB70_2709	COG1024	Enoyl-CoA hydratase
CSB70_2710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSB70_2712	COG2814	Major facilitator Superfamily
CSB70_2713	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSB70_2713	COG0047	phosphoribosylformylglycinamidine synthase activity
CSB70_2717	COG1473	amidohydrolase
CSB70_2718	COG0824	Thioesterase
CSB70_2722	COG0823	Involved in the tonB-independent uptake of proteins
CSB70_2726	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSB70_2735	COG0628	permease
CSB70_2737	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSB70_2738	COG0596	Alpha beta hydrolase
CSB70_2739	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSB70_2739	COG0616	signal peptide processing
CSB70_2741	COG2333	competence protein COMEC
CSB70_2741	COG0658	competence protein
CSB70_2742	COG1136	(ABC) transporter
CSB70_2743	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSB70_2749	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_2753	COG0463	Glycosyl transferase, family 2
CSB70_2759	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSB70_2760	COG1280	lysine exporter protein (LysE YggA)
CSB70_2761	COG2267	carboxylic ester hydrolase activity
CSB70_2763	COG0019	diaminopimelate decarboxylase activity
CSB70_2765	COG1113	amino acid transport
CSB70_2767	COG1115	amino acid carrier protein
CSB70_2772	COG3339	Conserved Protein
CSB70_2773	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSB70_2774	COG0243	molybdopterin cofactor binding
CSB70_2775	COG1929	Belongs to the glycerate kinase type-1 family
CSB70_2778	COG0778	Nitroreductase
CSB70_2784	COG0789	Transcriptional regulator
CSB70_2788	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB70_2792	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSB70_2798	COG0741	lytic transglycosylase activity
CSB70_2802	COG0584	glycerophosphoryl diester phosphodiesterase
CSB70_2803	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_2805	COG0582	viral genome integration into host DNA
CSB70_2809	COG1063	alcohol dehydrogenase
CSB70_2811	COG3179	chitinase
CSB70_2818	COG0741	lytic transglycosylase activity
CSB70_2818	COG0739	heme binding
CSB70_2818	COG1196	nuclear chromosome segregation
CSB70_2840	COG5410	chromosome segregation
CSB70_2875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSB70_2879	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CSB70_2880	COG0477	Major facilitator Superfamily
CSB70_2890	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSB70_2891	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSB70_2896	COG0505	Belongs to the CarA family
CSB70_2899	COG1309	transcriptional regulator
CSB70_2900	COG0251	oxidation-reduction process
CSB70_2902	COG0589	response to stress
CSB70_2905	COG2843	Capsule synthesis protein
CSB70_2910	COG2321	neutral zinc metallopeptidase
CSB70_2911	COG2354	Protein conserved in bacteria
CSB70_2915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB70_2919	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSB70_2920	COG1053	succinate dehydrogenase
CSB70_2921	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CSB70_2922	COG2009	succinate dehydrogenase
CSB70_2931	COG2921	Belongs to the UPF0250 family
CSB70_2932	COG0321	lipoyl(octanoyl) transferase activity
CSB70_2935	COG0531	amino acid
CSB70_2937	COG1733	regulation of RNA biosynthetic process
CSB70_2938	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CSB70_2939	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CSB70_2939	COG1648	precorrin-2 dehydrogenase activity
CSB70_2942	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CSB70_2947	COG0671	phosphoesterase, PA-phosphatase related
CSB70_2948	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_2950	COG1538	Outer membrane efflux protein
CSB70_2951	COG0393	Putative heavy-metal-binding
CSB70_2952	COG0393	Putative heavy-metal-binding
CSB70_2954	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_2956	COG0525	valine-tRNA ligase activity
CSB70_2957	COG2226	methyltransferase
CSB70_2960	COG0583	DNA-binding transcription factor activity
CSB70_2961	COG0004	ammonium transporteR
CSB70_2963	COG0642	Histidine kinase
CSB70_2964	COG0745	RESPONSE REGULATOR receiver
CSB70_2965	COG2194	sulfuric ester hydrolase activity
CSB70_2969	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSB70_2972	COG2315	Protein conserved in bacteria
CSB70_2973	COG0142	geranyltranstransferase activity
CSB70_2974	COG2828	Protein conserved in bacteria
CSB70_2976	COG1113	amino acid transport
CSB70_2980	COG2207	Transcriptional regulator
CSB70_2985	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_2989	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB70_2991	COG1530	ribonuclease E activity
CSB70_2992	COG0424	maF-like protein
CSB70_2994	COG1792	Involved in formation and maintenance of cell shape
CSB70_2995	COG1077	Cell shape determining protein MreB Mrl
CSB70_2996	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB70_2997	COG1077	Cell shape determining protein MreB Mrl
CSB70_2998	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB70_3000	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB70_3005	COG3590	peptidase
CSB70_3006	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CSB70_3007	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSB70_3008	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSB70_3009	COG1115	amino acid carrier protein
CSB70_3013	COG2814	Major facilitator Superfamily
CSB70_3014	COG1289	transmembrane transporter activity
CSB70_3024	COG1376	ErfK ybiS ycfS ynhG family protein
CSB70_3025	COG2832	Protein of unknown function (DUF454)
CSB70_3027	COG5510	response to toxic substance
CSB70_3030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSB70_3033	COG0840	transmembrane signaling receptor activity
CSB70_3041	COG3422	double-strand break repair
CSB70_3042	COG2824	Alkylphosphonate utilization operon protein PhnA
CSB70_3043	COG3189	MarR family transcriptional regulator
CSB70_3045	COG0354	folic acid binding
CSB70_3046	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB70_3048	COG0679	Auxin Efflux Carrier
CSB70_3049	COG1902	pentaerythritol trinitrate reductase activity
CSB70_3050	COG4772	TonB-dependent receptor
CSB70_3051	COG2094	Belongs to the DNA glycosylase MPG family
CSB70_3057	COG2233	PERMEase
CSB70_3059	COG0833	amino acid
CSB70_3060	COG1690	Belongs to the RtcB family
CSB70_3062	COG2885	chlorophyll binding
CSB70_3062	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CSB70_3064	COG0183	Belongs to the thiolase family
CSB70_3068	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB70_3073	COG2207	Transcriptional regulator
CSB70_3074	COG0183	Belongs to the thiolase family
CSB70_3075	COG1024	Enoyl-CoA hydratase
CSB70_3075	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB70_3079	COG2153	protein acetylation
CSB70_3081	COG1272	protein, Hemolysin III
CSB70_3082	COG0477	Major facilitator Superfamily
CSB70_3085	COG0450	alkyl hydroperoxide reductase
CSB70_3089	COG0285	dihydrofolate synthase activity
CSB70_3096	COG0133	tryptophan synthase activity
CSB70_3099	COG2096	Adenosyltransferase
CSB70_3100	COG0584	glycerophosphoryl diester phosphodiesterase
CSB70_3103	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CSB70_3104	COG0745	RESPONSE REGULATOR receiver
CSB70_3105	COG2205	protein histidine kinase activity
CSB70_3107	COG1960	acyl-CoA dehydrogenase activity
CSB70_3108	COG1960	acyl-CoA dehydrogenase activity
CSB70_3120	COG1215	transferase activity, transferring glycosyl groups
CSB70_3123	COG4372	Transposase
CSB70_3127	COG1091	dTDP-4-dehydrorhamnose reductase activity
CSB70_3131	COG0726	polysaccharide deacetylase
CSB70_3134	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CSB70_3135	COG2205	protein histidine kinase activity
CSB70_3144	COG1862	Preprotein translocase
CSB70_3146	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSB70_3147	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSB70_3149	COG3781	membrane
CSB70_3150	COG0613	PHP domain protein
CSB70_3152	COG2350	Protein conserved in bacteria
CSB70_3158	COG1607	acyl-coa hydrolase
CSB70_3161	COG3453	Protein conserved in bacteria
CSB70_3161	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_3170	COG2199	diguanylate cyclase activity
CSB70_3172	COG1408	metallophosphoesterase
CSB70_3173	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSB70_3175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSB70_3179	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CSB70_3180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CSB70_3181	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CSB70_3183	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CSB70_3185	COG2969	positive regulation of protein catabolic process
CSB70_3193	COG1960	acyl-CoA dehydrogenase activity
CSB70_3194	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSB70_3198	COG1309	transcriptional regulator
CSB70_3199	COG1960	acyl-CoA dehydrogenase activity
CSB70_3208	COG1183	phosphatidylcholine synthase activity
CSB70_3209	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CSB70_3215	COG0739	heme binding
CSB70_3215	COG1196	nuclear chromosome segregation
CSB70_3215	COG0741	lytic transglycosylase activity
CSB70_3217	COG1702	phosphate starvation-inducible protein PhoH
CSB70_3224	COG1295	ribonuclease BN
CSB70_3225	COG0697	spore germination
CSB70_3226	COG2169	Transcriptional regulator
CSB70_3227	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSB70_3236	COG0557	exoribonuclease II activity
CSB70_3237	COG0339	signal peptide processing
CSB70_3238	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CSB70_3245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CSB70_3246	COG1960	acyl-CoA dehydrogenase activity
CSB70_3251	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CSB70_3253	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CSB70_3277	COG0626	cystathionine gamma-synthase activity
CSB70_3278	COG0433	COG0433 Predicted ATPase
CSB70_3279	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_3279	COG1017	nitric oxide dioxygenase activity
CSB70_3280	COG1959	2 iron, 2 sulfur cluster binding
CSB70_3283	COG1301	dicarboxylic acid transport
CSB70_3284	COG1946	Acyl-CoA thioesterase
CSB70_3288	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSB70_3289	COG1040	competence protein
CSB70_3290	COG0494	nUDIX hydrolase
CSB70_3292	COG0598	Magnesium transport protein CorA
CSB70_3294	COG2854	intermembrane phospholipid transfer
CSB70_3296	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSB70_3297	COG1127	ABC transporter
CSB70_3299	COG0513	Belongs to the DEAD box helicase family
CSB70_3303	COG0408	coproporphyrinogen oxidase activity
CSB70_3306	COG1960	acyl-CoA dehydrogenase activity
CSB70_3308	COG1983	PspC domain protein
CSB70_3309	COG0517	IMP dehydrogenase activity
CSB70_3319	COG0583	DNA-binding transcription factor activity
CSB70_3327	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_3329	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSB70_3330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSB70_3332	COG0833	amino acid
CSB70_3339	COG0628	permease
CSB70_3341	COG1289	transmembrane transporter activity
CSB70_3344	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_3345	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CSB70_3347	COG0277	FAD linked oxidase domain protein
CSB70_3348	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSB70_3353	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CSB70_3354	COG5380	lipid catabolic process
CSB70_3358	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CSB70_3368	COG0194	GDP metabolic process
CSB70_3370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSB70_3374	COG3307	-O-antigen
CSB70_3377	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CSB70_3378	COG1704	LemA family
CSB70_3380	COG0493	'glutamate synthase
CSB70_3381	COG0070	glutamate synthase
CSB70_3381	COG0069	glutamate synthase activity
CSB70_3381	COG0067	glutamate synthase
CSB70_3391	COG2226	methyltransferase
CSB70_3394	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSB70_3395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSB70_3404	COG0833	amino acid
CSB70_3422	COG0488	(ABC) transporter
CSB70_3424	COG4221	oxidoreductase activity
CSB70_3425	COG0659	secondary active sulfate transmembrane transporter activity
CSB70_3427	COG0745	RESPONSE REGULATOR receiver
CSB70_3429	COG0427	acetyl-CoA hydrolase
CSB70_3435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CSB70_3441	COG2329	Antibiotic biosynthesis monooxygenase
CSB70_3444	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSB70_3458	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_3459	COG1733	regulation of RNA biosynthetic process
CSB70_3468	COG0667	Aldo Keto reductase
CSB70_3472	COG0583	DNA-binding transcription factor activity
CSB70_3473	COG2814	Major facilitator Superfamily
CSB70_3479	COG4372	Transposase
CSB70_3484	COG1335	isochorismatase
CSB70_3486	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_3487	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSB70_3489	COG1113	amino acid transport
CSB70_3491	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CSB70_3494	COG2814	Major facilitator Superfamily
CSB70_3496	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSB70_3496	COG0351	phosphomethylpyrimidine kinase
CSB70_3496	COG0352	thiamine-phosphate diphosphorylase activity
CSB70_3500	COG1309	transcriptional regulator
CSB70_3501	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSB70_3503	COG3706	GGDEF domain
CSB70_3505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB70_3507	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSB70_3508	COG3162	membrane
CSB70_3509	COG0784	Response regulator, receiver
CSB70_3509	COG2198	Histidine kinase
CSB70_3509	COG2205	protein histidine kinase activity
CSB70_3514	COG1522	sequence-specific DNA binding
CSB70_3515	COG1335	isochorismatase
CSB70_3516	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB70_3518	COG0668	transmembrane transport
CSB70_3519	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSB70_3520	COG1519	Transferase
CSB70_3521	COG1902	pentaerythritol trinitrate reductase activity
CSB70_3527	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSB70_3532	COG0426	domain, Protein
CSB70_3532	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_3533	COG4774	siderophore transport
CSB70_3534	COG2119	membrane
CSB70_3535	COG4372	Transposase
CSB70_3538	COG2119	membrane
CSB70_3540	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSB70_3542	COG4942	peptidase
CSB70_3545	COG4372	Transposase
CSB70_3548	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSB70_3550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CSB70_3554	COG0189	ligase activity
CSB70_3558	COG0708	Exodeoxyribonuclease III
CSB70_3559	COG1393	Belongs to the ArsC family
CSB70_3562	COG3706	GGDEF domain
CSB70_3569	COG2351	hydroxyisourate hydrolase activity
CSB70_3570	COG2233	PERMEase
CSB70_3572	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_3574	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CSB70_3575	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_3578	COG3150	esterase
CSB70_3581	COG1388	LysM domain
CSB70_3581	COG0791	NLP P60 protein
CSB70_3582	COG3501	Rhs element vgr protein
CSB70_3584	COG2918	glutathione biosynthetic process
CSB70_3587	COG2733	membrane
CSB70_3588	COG0436	Aminotransferase
CSB70_3589	COG0534	Mate efflux family protein
CSB70_3609	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CSB70_3611	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSB70_3613	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSB70_3614	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CSB70_3617	COG0010	Belongs to the arginase family
CSB70_3623	COG2188	Transcriptional regulator
CSB70_3625	COG0523	cobalamin synthesis protein
CSB70_3627	COG1113	amino acid transport
CSB70_3629	COG0625	glutathione transferase activity
CSB70_3633	COG1683	Conserved Protein
CSB70_3634	COG0534	Mate efflux family protein
CSB70_3635	COG0385	Bile acid
CSB70_3636	COG1335	isochorismatase
CSB70_3637	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB70_3641	COG2116	formate transmembrane transporter activity
CSB70_3642	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSB70_3643	COG2133	pyrroloquinoline quinone binding
CSB70_3644	COG2983	Belongs to the UPF0260 family
CSB70_3648	COG1194	a g-specific adenine glycosylase
CSB70_3651	COG2818	Glycosylase
CSB70_3652	COG1064	alcohol dehydrogenase
CSB70_3653	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_3656	COG0583	DNA-binding transcription factor activity
CSB70_3657	COG0656	L-ascorbic acid biosynthetic process
CSB70_3658	COG2814	Major facilitator Superfamily
CSB70_3665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_3669	COG2233	PERMEase
CSB70_3677	COG0733	neurotransmitter:sodium symporter activity
CSB70_3683	COG4372	Transposase
CSB70_3690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CSB70_3691	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CSB70_3692	COG0596	Alpha beta hydrolase
CSB70_3701	COG0488	(ABC) transporter
CSB70_3702	COG0586	Pfam SNARE associated Golgi protein
CSB70_3704	COG0187	DNA topoisomerase II activity
CSB70_3706	COG0592	DNA-directed DNA polymerase activity
CSB70_3708	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CSB70_3711	COG0706	membrane insertase activity
CSB70_3714	COG1230	cation diffusion facilitator family transporter
CSB70_3715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB70_3719	COG0402	S-adenosylhomocysteine deaminase activity
CSB70_3721	COG0754	glutathionylspermidine amidase activity
CSB70_3723	COG0861	Integral membrane protein TerC family
CSB70_3724	COG0671	phosphoesterase, PA-phosphatase related
CSB70_3726	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSB70_3730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CSB70_3731	COG2951	lytic endotransglycosylase activity
CSB70_3737	COG0583	DNA-binding transcription factor activity
CSB70_3742	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSB70_3750	COG1047	Peptidyl-prolyl cis-trans
CSB70_3752	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CSB70_3753	COG0196	riboflavin kinase activity
CSB70_3755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSB70_3756	COG1309	transcriptional regulator
CSB70_3757	COG1116	anion transmembrane transporter activity
CSB70_3758	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB70_3759	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSB70_3760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB70_3761	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB70_3765	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_3766	COG0546	phosphoglycolate phosphatase activity
CSB70_3778	COG3023	N-Acetylmuramoyl-L-alanine amidase
CSB70_3779	COG0728	peptidoglycan biosynthetic process
CSB70_3784	COG1596	polysaccharide export
CSB70_3785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSB70_3796	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSB70_3797	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSB70_3798	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSB70_3801	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSB70_3803	COG2186	Transcriptional regulator
CSB70_3805	COG0277	FAD linked oxidase domain protein
CSB70_3806	COG1448	Aminotransferase
CSB70_3807	COG1802	Transcriptional regulator
CSB70_3810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CSB70_3811	COG1196	nuclear chromosome segregation
CSB70_3823	COG0564	pseudouridine synthase activity
CSB70_3828	COG1522	sequence-specific DNA binding
CSB70_3831	COG0251	oxidation-reduction process
CSB70_3832	COG1113	amino acid transport
CSB70_3833	COG1113	amino acid transport
CSB70_3837	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB70_3838	COG1960	acyl-CoA dehydrogenase activity
CSB70_3839	COG1024	Enoyl-CoA hydratase
CSB70_3840	COG1024	Enoyl-CoA hydratase
CSB70_3841	COG0477	Major facilitator Superfamily
CSB70_3842	COG0019	diaminopimelate decarboxylase activity
CSB70_3846	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CSB70_3847	COG1846	Transcriptional regulator
CSB70_3848	COG3916	Acyl-homoserine-lactone synthase
CSB70_3850	COG2197	response regulator
CSB70_3852	COG1960	acyl-CoA dehydrogenase activity
CSB70_3853	COG3321	synthase
CSB70_3853	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSB70_3853	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSB70_3853	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CSB70_3861	COG0271	Belongs to the BolA IbaG family
CSB70_3863	COG1192	Involved in chromosome partitioning
CSB70_3866	COG0586	Pfam SNARE associated Golgi protein
CSB70_3867	COG2259	Doxx family
CSB70_3868	COG4399	Belongs to the UPF0754 family
CSB70_3869	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSB70_3869	COG0519	Catalyzes the synthesis of GMP from XMP
CSB70_3878	COG0281	malic enzyme
CSB70_3879	COG2837	iron assimilation
CSB70_3882	COG1280	lysine exporter protein (LysE YggA)
CSB70_3883	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSB70_3884	COG1121	(ABC) transporter
CSB70_3897	COG0386	Belongs to the glutathione peroxidase family
CSB70_3899	COG4372	Transposase
CSB70_3903	COG1309	transcriptional regulator
CSB70_3904	COG0697	spore germination
CSB70_3906	COG0758	DNA mediated transformation
CSB70_3913	COG1309	transcriptional regulator
CSB70_3919	COG4372	Transposase
CSB70_3923	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSB70_3925	COG0655	NAD(P)H dehydrogenase (quinone) activity
CSB70_3935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSB70_3939	COG1253	flavin adenine dinucleotide binding
CSB70_3941	COG2860	membrane
CSB70_3942	COG0477	Major facilitator Superfamily
CSB70_3944	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_3947	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSB70_3951	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB70_3953	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_3954	COG0606	chelatase, subunit chli
CSB70_3960	COG2072	flavoprotein involved in K transport
CSB70_3961	COG0492	ferredoxin-NADP+ reductase activity
CSB70_3962	COG0431	NADPH-dependent FMN reductase
CSB70_3963	COG0798	PFAM Bile acid sodium symporter
CSB70_3965	COG0640	Transcriptional regulator
CSB70_3967	COG0589	response to stress
CSB70_3968	COG0659	secondary active sulfate transmembrane transporter activity
CSB70_3973	COG0606	chelatase, subunit chli
CSB70_3975	COG0347	Belongs to the P(II) protein family
CSB70_3976	COG0004	ammonium transporteR
CSB70_3978	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSB70_3978	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSB70_3986	COG0795	lipopolysaccharide-transporting ATPase activity
CSB70_3987	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CSB70_3988	COG0793	Belongs to the peptidase S41A family
CSB70_3991	COG2197	response regulator
CSB70_3993	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSB70_3995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB70_3996	COG4974	Belongs to the 'phage' integrase family
CSB70_4001	COG0772	Belongs to the SEDS family
CSB70_4002	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSB70_4003	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSB70_4004	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSB70_4009	COG0697	spore germination
CSB70_4010	COG1538	Outer membrane efflux protein
CSB70_4014	COG3275	phosphorelay sensor kinase activity
CSB70_4016	COG0181	hydroxymethylbilane synthase activity
CSB70_4025	COG1716	ATPase activity
CSB70_4026	COG0546	phosphoglycolate phosphatase activity
CSB70_4037	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSB70_4040	COG1388	LysM domain
CSB70_4057	COG4993	Dehydrogenase
CSB70_4073	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB70_4074	COG3657	addiction module killer protein
CSB70_4082	COG4221	oxidoreductase activity
CSB70_4083	COG0583	DNA-binding transcription factor activity
CSB70_4084	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CSB70_4085	COG0604	alcohol dehydrogenase
CSB70_4085	COG3321	synthase
CSB70_4088	COG3328	transposase activity
CSB70_4089	COG3328	transposase activity
CSB70_4096	COG1063	alcohol dehydrogenase
CSB70_4100	COG4372	Transposase
CSB70_4102	COG3316	Transposase and inactivated derivatives
CSB70_4103	COG0475	glutathione-regulated potassium exporter activity
CSB70_4103	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB70_4109	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CSB70_4111	COG1979	alcohol dehydrogenase
CSB70_4113	COG1902	pentaerythritol trinitrate reductase activity
CSB70_4115	COG1309	transcriptional regulator
CSB70_4116	COG2130	NADP-dependent
CSB70_4119	COG0582	viral genome integration into host DNA
CSB70_4120	COG3328	transposase activity
CSB70_4129	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSB70_4134	COG0194	GDP metabolic process
CSB70_4141	COG0358	DNA primase activity
CSB70_4150	COG3328	transposase activity
CSB70_4153	COG1764	response to oxidative stress
CSB70_4154	COG1764	response to oxidative stress
CSB70_4155	COG1846	Transcriptional regulator
CSB70_4163	COG1846	Transcriptional regulator
CSB70_4164	COG1764	response to oxidative stress
CSB70_4165	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_4172	COG1764	response to oxidative stress
CSB70_4173	COG1846	Transcriptional regulator
CSB70_4181	COG1846	Transcriptional regulator
CSB70_4182	COG1764	response to oxidative stress
CSB70_4189	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_4190	COG1764	response to oxidative stress
CSB70_4191	COG1846	Transcriptional regulator
CSB70_4197	COG1846	Transcriptional regulator
CSB70_4198	COG1764	response to oxidative stress
CSB70_4205	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_4206	COG1764	response to oxidative stress
CSB70_4207	COG1846	Transcriptional regulator
CSB70_4213	COG1846	Transcriptional regulator
CSB70_4214	COG1764	response to oxidative stress
CSB70_4215	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_4222	COG1764	response to oxidative stress
CSB70_4223	COG1846	Transcriptional regulator
CSB70_4230	COG1846	Transcriptional regulator
CSB70_4231	COG1764	response to oxidative stress
CSB70_4238	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_4239	COG1764	response to oxidative stress
CSB70_4240	COG1846	Transcriptional regulator
CSB70_4246	COG1846	Transcriptional regulator
CSB70_4247	COG1764	response to oxidative stress
CSB70_4248	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_4255	COG1764	response to oxidative stress
CSB70_4256	COG1846	Transcriptional regulator
CSB70_4262	COG1846	Transcriptional regulator
CSB70_4263	COG1764	response to oxidative stress
CSB70_4264	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_4286	COG4644	lycopene metabolic process
CSB70_4294	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CSB70_4296	COG1192	Involved in chromosome partitioning
CSB70_4300	COG2026	Addiction module toxin, RelE StbE family
CSB70_4305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CSB70_4315	COG4644	lycopene metabolic process