locus-tag	class	description
AM462_00035	COG1215	transferase activity, transferring glycosyl groups
AM462_00050	COG0415	Belongs to the DNA photolyase family
AM462_00060	COG1252	NADH dehydrogenase
AM462_00065	COG1686	Belongs to the peptidase S11 family
AM462_00080	COG1187	pseudouridine synthase activity
AM462_00105	COG0477	Major facilitator Superfamily
AM462_00110	COG0583	DNA-binding transcription factor activity
AM462_00125	COG0612	Peptidase, M16
AM462_00155	COG1203	CRISPR-associated helicase, Cas3
AM462_00180	COG0352	thiamine-phosphate diphosphorylase activity
AM462_00215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_00230	COG1309	transcriptional regulator
AM462_00240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM462_00245	COG0076	glutamate decarboxylase activity
AM462_00255	COG1522	sequence-specific DNA binding
AM462_00260	COG3961	Belongs to the TPP enzyme family
AM462_00265	COG1113	amino acid transport
AM462_00270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM462_00275	COG0573	inorganic phosphate transmembrane transporter activity
AM462_00285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM462_00290	COG0616	signal peptide processing
AM462_00325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM462_00330	COG1686	Belongs to the peptidase S11 family
AM462_00355	COG0583	DNA-binding transcription factor activity
AM462_00360	COG1067	ATP-dependent peptidase activity
AM462_00385	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM462_00405	COG1966	Carbon starvation protein
AM462_00410	COG2879	small protein
AM462_00420	COG0583	DNA-binding transcription factor activity
AM462_00425	COG0006	proline dipeptidase activity
AM462_00430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_00435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_00450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_00455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM462_00455	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM462_00510	COG1741	Belongs to the pirin family
AM462_00520	COG2964	Protein conserved in bacteria
AM462_00535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM462_00540	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM462_00545	COG4605	iron ion homeostasis
AM462_00550	COG4604	ABC transporter, ATP-binding protein
AM462_00555	COG4607	ABC-type enterochelin transport system periplasmic component
AM462_00560	COG4774	siderophore transport
AM462_00570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM462_00575	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM462_00580	COG1535	isochorismatase
AM462_00580	COG3433	isochorismatase activity
AM462_00595	COG1132	(ABC) transporter
AM462_00605	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AM462_00615	COG1169	isochorismate synthase
AM462_00630	COG3739	integral membrane protein
AM462_00665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM462_00695	COG0308	aminopeptidase N
AM462_00700	COG0512	Glutamine amidotransferase of anthranilate synthase
AM462_00710	COG3104	oligopeptide transport
AM462_00725	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM462_00760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM462_00765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM462_00770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM462_00790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM462_00795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM462_00800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM462_00815	COG1960	acyl-CoA dehydrogenase activity
AM462_00820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM462_00825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM462_00835	COG2223	nitrite transmembrane transporter activity
AM462_00845	COG0024	Methionine aminopeptidase
AM462_00850	COG0052	Belongs to the universal ribosomal protein uS2 family
AM462_00865	COG2207	Transcriptional regulator
AM462_00890	COG2951	lytic endotransglycosylase activity
AM462_00895	COG0772	Belongs to the SEDS family
AM462_00910	COG0842	Transport permease protein
AM462_00915	COG1131	(ABC) transporter
AM462_00920	COG0582	viral genome integration into host DNA
AM462_01240	COG0739	heme binding
AM462_01325	COG1538	Outer membrane efflux protein
AM462_01335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_01355	COG4215	(ABC) transporter
AM462_01360	COG4160	amino acid transport
AM462_01365	COG4598	ABC transporter
AM462_01375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM462_01385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM462_01400	COG1720	tRNA m6t6A37 methyltransferase activity
AM462_01420	COG0745	RESPONSE REGULATOR receiver
AM462_01425	COG0642	Histidine kinase
AM462_01435	COG0494	nUDIX hydrolase
AM462_01445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM462_01450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM462_01455	COG3139	Protein of unknown function (DUF1315)
AM462_01460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM462_01470	COG1301	dicarboxylic acid transport
AM462_01475	COG1960	acyl-CoA dehydrogenase activity
AM462_01480	COG2819	hydrolase of the alpha beta superfamily
AM462_01490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM462_01500	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM462_01505	COG1234	tRNA 3'-trailer cleavage
AM462_01530	COG2363	Small membrane protein
AM462_01550	COG0513	Belongs to the DEAD box helicase family
AM462_01560	COG0778	Nitroreductase
AM462_01590	COG1286	toxin biosynthetic process
AM462_01615	COG4783	chaperone-mediated protein folding
AM462_01620	COG1610	YqeY-like protein
AM462_01625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM462_01720	COG3111	PFAM Bacterial OB fold (BOF) protein
AM462_01745	COG3243	poly(R)-hydroxyalkanoic acid synthase
AM462_01750	COG0786	glutamate:sodium symporter activity
AM462_01760	COG0583	DNA-binding transcription factor activity
AM462_01770	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_01785	COG2186	Transcriptional regulator
AM462_01845	COG0477	Major facilitator Superfamily
AM462_01870	COG2995	paraquat-inducible protein a
AM462_01875	COG3008	intermembrane lipid transfer
AM462_01875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM462_01885	COG2351	hydroxyisourate hydrolase activity
AM462_01925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM462_01935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM462_01940	COG0642	Histidine kinase
AM462_01945	COG0745	RESPONSE REGULATOR receiver
AM462_01965	COG1794	racemase activity, acting on amino acids and derivatives
AM462_01995	COG1301	dicarboxylic acid transport
AM462_02005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_02010	COG2011	ABC-type metal ion transport system permease component
AM462_02015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM462_02020	COG1464	Belongs to the NlpA lipoprotein family
AM462_02025	COG0151	Belongs to the GarS family
AM462_02030	COG0138	bifunctional purine biosynthesis protein purh
AM462_02035	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AM462_02065	COG2308	Evidence 4 Homologs of previously reported genes of
AM462_02075	COG1305	Transglutaminase-like
AM462_02085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM462_02090	COG0305	Participates in initiation and elongation during chromosome replication
AM462_02115	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM462_02125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM462_02130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM462_02155	COG1649	PFAM Uncharacterised BCR, COG1649
AM462_02155	COG0726	polysaccharide deacetylase
AM462_02160	COG1215	transferase activity, transferring glycosyl groups
AM462_02165	COG3658	cytochrome
AM462_02175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM462_02195	COG0583	DNA-binding transcription factor activity
AM462_02215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM462_02220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM462_02240	COG1960	acyl-CoA dehydrogenase activity
AM462_02245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM462_02250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_02275	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM462_02280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM462_02290	COG2205	protein histidine kinase activity
AM462_02295	COG0745	RESPONSE REGULATOR receiver
AM462_02300	COG0174	glutamine synthetase
AM462_02320	COG0729	surface antigen
AM462_02350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM462_02355	COG2814	Major facilitator Superfamily
AM462_02445	COG4397	Mu-like prophage major head subunit gpT
AM462_02460	COG5005	Phage virion morphogenesis
AM462_02465	COG2369	cell adhesion
AM462_02470	COG4383	Mu-like prophage protein gp29
AM462_02480	COG4373	Mu-like prophage FluMu protein gp28
AM462_02545	COG3267	Type II secretory pathway component ExeA
AM462_02545	COG3409	Peptidoglycan-binding domain 1 protein
AM462_02570	COG0776	regulation of translation
AM462_02615	COG0583	DNA-binding transcription factor activity
AM462_02630	COG1187	pseudouridine synthase activity
AM462_02650	COG0802	atpase or kinase
AM462_02655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM462_02665	COG1923	regulation of RNA biosynthetic process
AM462_02670	COG0697	spore germination
AM462_02700	COG0519	Catalyzes the synthesis of GMP from XMP
AM462_02700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM462_02705	COG4302	ethanolamine ammonia-lyase activity
AM462_02710	COG4303	Ethanolamine ammonia lyase large subunit
AM462_02715	COG0531	amino acid
AM462_02735	COG1454	alcohol dehydrogenase
AM462_02740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM462_02765	COG0308	aminopeptidase N
AM462_02770	COG2826	transposase and inactivated derivatives, IS30 family
AM462_02810	COG1605	Chorismate mutase
AM462_02830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM462_02850	COG1309	transcriptional regulator
AM462_02860	COG0668	transmembrane transport
AM462_02895	COG4773	Receptor
AM462_02915	COG0488	(ABC) transporter
AM462_02920	COG0589	response to stress
AM462_02935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM462_02945	COG3135	benzoate transporter
AM462_02950	COG1522	sequence-specific DNA binding
AM462_02965	COG0583	DNA-binding transcription factor activity
AM462_02975	COG0183	Belongs to the thiolase family
AM462_03005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM462_03015	COG0824	Thioesterase
AM462_03020	COG1454	alcohol dehydrogenase
AM462_03030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM462_03050	COG0069	glutamate synthase activity
AM462_03095	COG0511	ligase activity, forming carbon-carbon bonds
AM462_03115	COG1116	anion transmembrane transporter activity
AM462_03115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM462_03120	COG0745	RESPONSE REGULATOR receiver
AM462_03130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_03130	COG2146	nitrite reductase [NAD(P)H] activity
AM462_03135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_03140	COG0243	molybdopterin cofactor binding
AM462_03150	COG0243	molybdopterin cofactor binding
AM462_03155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM462_03170	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM462_03170	COG0315	cyclic pyranopterin monophosphate synthase activity
AM462_03175	COG0303	'Molybdopterin
AM462_03190	COG0697	spore germination
AM462_03210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM462_03215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM462_03275	COG2204	response regulator
AM462_03280	COG3852	Histidine kinase
AM462_03305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM462_03310	COG0575	Belongs to the CDS family
AM462_03345	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM462_03360	COG2137	regulation of response to DNA damage stimulus
AM462_03370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM462_03375	COG1011	Hydrolase
AM462_03400	COG1522	sequence-specific DNA binding
AM462_03410	COG1113	amino acid transport
AM462_03425	COG0659	secondary active sulfate transmembrane transporter activity
AM462_03430	COG2135	peptidase activity
AM462_03445	COG5001	Diguanylate cyclase
AM462_03445	COG3300	MHYT domain
AM462_03465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM462_03465	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM462_03465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM462_03470	COG1105	Belongs to the carbohydrate kinase PfkB family
AM462_03475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM462_03475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM462_03505	COG0024	Methionine aminopeptidase
AM462_03510	COG0583	DNA-binding transcription factor activity
AM462_03520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM462_03525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM462_03530	COG0516	GMP reductase activity
AM462_03530	COG0517	IMP dehydrogenase activity
AM462_03555	COG0552	protein localization to endoplasmic reticulum
AM462_03565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AM462_03575	COG4890	Cyd operon protein YbgT
AM462_03580	COG1294	oxidase, subunit
AM462_03595	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM462_03605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM462_03625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM462_03630	COG0569	domain protein
AM462_03635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM462_03665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM462_03670	COG0542	response to heat
AM462_03680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM462_03695	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM462_03695	COG1902	pentaerythritol trinitrate reductase activity
AM462_03740	COG2323	membrane
AM462_03745	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AM462_03755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM462_03760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM462_03765	COG0183	Belongs to the thiolase family
AM462_03770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM462_03775	COG0596	Alpha beta hydrolase
AM462_03780	COG2271	Major facilitator Superfamily
AM462_03785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM462_03790	COG3485	protocatechuate 3,4-dioxygenase
AM462_03795	COG3485	protocatechuate 3,4-dioxygenase
AM462_03800	COG0710	3-dehydroquinate dehydratase activity
AM462_03805	COG3420	alginic acid biosynthetic process
AM462_03810	COG3659	wide pore channel activity
AM462_03815	COG4993	Dehydrogenase
AM462_03825	COG2391	methyltransferase activity
AM462_03840	COG1414	Transcriptional regulator
AM462_03845	COG0583	DNA-binding transcription factor activity
AM462_03850	COG1960	acyl-CoA dehydrogenase activity
AM462_03875	COG2814	Major facilitator Superfamily
AM462_03895	COG0154	amidase activity
AM462_03915	COG4638	Rieske (2fe-2S)
AM462_03925	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_03935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_03945	COG3733	amine oxidase
AM462_03955	COG1012	belongs to the aldehyde dehydrogenase family
AM462_03965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM462_03970	COG0183	Belongs to the thiolase family
AM462_03980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM462_03985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM462_03995	COG4829	muconolactone delta-isomerase
AM462_04000	COG4948	Mandelate Racemase Muconate Lactonizing
AM462_04005	COG0583	DNA-binding transcription factor activity
AM462_04015	COG2186	Transcriptional regulator
AM462_04035	COG1012	belongs to the aldehyde dehydrogenase family
AM462_04050	COG1902	pentaerythritol trinitrate reductase activity
AM462_04050	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM462_04090	COG1309	transcriptional regulator
AM462_04100	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_04105	COG4689	acetoacetate decarboxylase
AM462_04115	COG1902	pentaerythritol trinitrate reductase activity
AM462_04135	COG1335	isochorismatase
AM462_04140	COG0583	DNA-binding transcription factor activity
AM462_04150	COG0475	glutathione-regulated potassium exporter activity
AM462_04150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM462_04160	COG1473	amidohydrolase
AM462_04330	COG0583	DNA-binding transcription factor activity
AM462_04345	COG1566	PFAM secretion protein HlyD family protein
AM462_04360	COG1012	belongs to the aldehyde dehydrogenase family
AM462_04365	COG0129	dihydroxy-acid dehydratase activity
AM462_04375	COG0583	DNA-binding transcription factor activity
AM462_04380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM462_04390	COG2084	Dehydrogenase
AM462_04405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM462_04465	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM462_04480	COG0556	nucleotide-excision repair
AM462_04520	COG1073	alpha beta
AM462_04530	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_04545	COG2207	Transcriptional regulator
AM462_04555	COG2205	protein histidine kinase activity
AM462_04560	COG0745	RESPONSE REGULATOR receiver
AM462_04565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_04570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM462_04575	COG1538	Outer membrane efflux protein
AM462_04585	COG2072	flavoprotein involved in K transport
AM462_04600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM462_04680	COG3539	Fimbrial protein
AM462_04705	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AM462_04715	COG0753	catalase activity
AM462_04730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM462_04795	COG3433	isochorismatase activity
AM462_04795	COG1535	isochorismatase
AM462_04800	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_04805	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM462_04810	COG4149	molybdate abc transporter
AM462_04820	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM462_04830	COG4638	Rieske (2fe-2S)
AM462_04835	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM462_04840	COG0543	2 iron, 2 sulfur cluster binding
AM462_04840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_04855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_04865	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_04870	COG0412	Dienelactone hydrolase
AM462_04880	COG2207	Transcriptional regulator
AM462_04885	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_04890	COG2610	gluconate transmembrane transporter activity
AM462_04900	COG0583	DNA-binding transcription factor activity
AM462_04915	COG2031	fatty acid transporter
AM462_04920	COG0183	Belongs to the thiolase family
AM462_04925	COG0583	DNA-binding transcription factor activity
AM462_04930	COG0583	DNA-binding transcription factor activity
AM462_04945	COG1027	Aspartate ammonia-lyase
AM462_04955	COG0477	Major facilitator Superfamily
AM462_04975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM462_04980	COG4521	taurine ABC transporter
AM462_05005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM462_05010	COG1733	regulation of RNA biosynthetic process
AM462_05015	COG2207	Transcriptional regulator
AM462_05015	COG3708	Transcriptional regulator
AM462_05030	COG0730	response to heat
AM462_05040	COG3453	Protein conserved in bacteria
AM462_05040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_05050	COG3781	membrane
AM462_05055	COG1063	alcohol dehydrogenase
AM462_05065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM462_05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM462_05075	COG0022	dehydrogenase e1 component
AM462_05080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM462_05085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM462_05100	COG3706	GGDEF domain
AM462_05115	COG0133	tryptophan synthase activity
AM462_05125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM462_05160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM462_05185	COG2226	methyltransferase
AM462_05240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM462_05245	COG4773	Receptor
AM462_05265	COG0730	response to heat
AM462_05270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM462_05285	COG0406	alpha-ribazole phosphatase activity
AM462_05290	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AM462_05305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM462_05335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM462_05345	COG4264	IucA IucC family
AM462_05350	COG4264	IucA IucC family
AM462_05355	COG2814	Major facilitator Superfamily
AM462_05370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM462_05385	COG1960	acyl-CoA dehydrogenase activity
AM462_05390	COG1960	acyl-CoA dehydrogenase activity
AM462_05395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM462_05400	COG2207	Transcriptional regulator
AM462_05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM462_05410	COG0776	regulation of translation
AM462_05435	COG0822	iron-sulfur transferase activity
AM462_05440	COG0316	Belongs to the HesB IscA family
AM462_05470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM462_05490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM462_05495	COG0702	epimerase
AM462_05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM462_05540	COG0339	signal peptide processing
AM462_05560	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM462_05585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM462_05590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM462_05620	COG0776	regulation of translation
AM462_05640	COG0590	tRNA wobble adenosine to inosine editing
AM462_05685	COG0084	hydrolase, TatD family'
AM462_05705	COG1663	tetraacyldisaccharide 4'-kinase activity
AM462_05710	COG1132	(ABC) transporter
AM462_05720	COG0811	peptide transport
AM462_05725	COG1475	DNA binding
AM462_05730	COG1192	Involved in chromosome partitioning
AM462_05740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM462_05755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM462_05760	COG0191	fructose-bisphosphate aldolase activity
AM462_05780	COG0424	maF-like protein
AM462_05785	COG2850	peptidyl-arginine hydroxylation
AM462_05795	COG0640	Transcriptional regulator
AM462_05805	COG3619	membrane
AM462_05810	COG3122	Protein conserved in bacteria
AM462_05815	COG1132	(ABC) transporter
AM462_05835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM462_05840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM462_05850	COG0506	proline dehydrogenase activity
AM462_05850	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM462_05850	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM462_05855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM462_05870	COG3698	Phosphodiester glycosidase
AM462_05880	COG2353	YceI-like domain
AM462_05890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM462_05935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM462_05935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM462_05960	COG3539	Fimbrial protein
AM462_05965	COG3121	Chaperone
AM462_05995	COG0697	spore germination
AM462_06005	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM462_06015	COG0583	DNA-binding transcription factor activity
AM462_06035	COG1309	transcriptional regulator
AM462_06050	COG1522	sequence-specific DNA binding
AM462_06060	COG1126	abc transporter atp-binding protein
AM462_06065	COG0765	amino acid transport
AM462_06070	COG0765	amino acid transport
AM462_06100	COG1464	Belongs to the NlpA lipoprotein family
AM462_06110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM462_06115	COG2011	ABC-type metal ion transport system permease component
AM462_06120	COG0012	GTP binding
AM462_06145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM462_06185	COG0386	Belongs to the glutathione peroxidase family
AM462_06195	COG0436	Aminotransferase
AM462_06200	COG1301	dicarboxylic acid transport
AM462_06235	COG3634	alkyl hydroperoxide reductase activity
AM462_06250	COG0583	DNA-binding transcription factor activity
AM462_06255	COG0798	PFAM Bile acid sodium symporter
AM462_06260	COG0640	Transcriptional regulator
AM462_06275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AM462_06285	COG0583	DNA-binding transcription factor activity
AM462_06295	COG1953	Uracil, thiamine, allantoin
AM462_06305	COG2175	clavaminate synthase activity
AM462_06310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM462_06315	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM462_06320	COG4521	taurine ABC transporter
AM462_06330	COG0477	Major facilitator Superfamily
AM462_06355	COG1271	oxidase subunit
AM462_06360	COG1294	oxidase, subunit
AM462_06370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM462_06390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM462_06410	COG3052	prosthetic group binding
AM462_06415	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AM462_06425	COG2814	Major facilitator Superfamily
AM462_06440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM462_06445	COG1346	cytolysis
AM462_06455	COG0583	DNA-binding transcription factor activity
AM462_06460	COG0625	glutathione transferase activity
AM462_06465	COG0625	glutathione transferase activity
AM462_06470	COG0583	DNA-binding transcription factor activity
AM462_06485	COG1045	serine acetyltransferase
AM462_06490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM462_06495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM462_06500	COG1280	lysine exporter protein (LysE YggA)
AM462_06510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM462_06515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM462_06520	COG1126	abc transporter atp-binding protein
AM462_06525	COG0765	amino acid transport
AM462_06530	COG0765	amino acid transport
AM462_06550	COG2205	protein histidine kinase activity
AM462_06550	COG0784	Response regulator, receiver
AM462_06590	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_06635	COG0583	DNA-binding transcription factor activity
AM462_06655	COG0318	PFAM AMP-dependent synthetase and ligase
AM462_06660	COG1309	transcriptional regulator
AM462_06665	COG1960	acyl-CoA dehydrogenase activity
AM462_06670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM462_06675	COG1024	Enoyl-CoA hydratase
AM462_06690	COG0583	DNA-binding transcription factor activity
AM462_06705	COG1960	acyl-CoA dehydrogenase activity
AM462_06715	COG2814	Major facilitator Superfamily
AM462_06725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM462_06730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM462_06735	COG2814	Major facilitator Superfamily
AM462_06740	COG1960	acyl-CoA dehydrogenase activity
AM462_06745	COG1024	Enoyl-CoA hydratase
AM462_06750	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_06755	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM462_06760	COG0183	Belongs to the thiolase family
AM462_06770	COG2814	Major facilitator Superfamily
AM462_06780	COG1024	Enoyl-CoA hydratase
AM462_06790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM462_06795	COG1960	acyl-CoA dehydrogenase activity
AM462_06800	COG2814	Major facilitator Superfamily
AM462_06805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM462_06810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM462_06825	COG3842	ATPase activity
AM462_06830	COG1840	ABC-type Fe3 transport system, periplasmic component
AM462_06840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_06845	COG1414	Transcriptional regulator
AM462_06855	COG0583	DNA-binding transcription factor activity
AM462_06860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM462_06865	COG1012	belongs to the aldehyde dehydrogenase family
AM462_06875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM462_06885	COG1012	belongs to the aldehyde dehydrogenase family
AM462_06890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM462_06895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_06900	COG2267	carboxylic ester hydrolase activity
AM462_06920	COG3038	cytochrome b561
AM462_06925	COG0753	catalase activity
AM462_06930	COG2271	Major facilitator Superfamily
AM462_06935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM462_06940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM462_06970	COG1278	Cold shock
AM462_07010	COG0210	DNA helicase
AM462_07015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM462_07020	COG2050	protein possibly involved in aromatic compounds catabolism
AM462_07030	COG3327	negative regulation of DNA-templated transcription, initiation
AM462_07035	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM462_07040	COG0183	Belongs to the thiolase family
AM462_07045	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM462_07050	COG1024	Enoyl-CoA hydratase
AM462_07055	COG1024	Enoyl-CoA hydratase
AM462_07060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_07065	COG2151	metal-sulfur cluster biosynthetic enzyme
AM462_07070	COG3396	Phenylacetate-CoA oxygenase
AM462_07075	COG3460	Phenylacetate-CoA oxygenase
AM462_07080	COG3396	Phenylacetate-CoA oxygenase
AM462_07085	COG2030	dehydratase
AM462_07085	COG1012	belongs to the aldehyde dehydrogenase family
AM462_07090	COG1760	l-serine dehydratase
AM462_07095	COG0531	amino acid
AM462_07100	COG1012	belongs to the aldehyde dehydrogenase family
AM462_07125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM462_07145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM462_07160	COG0789	Transcriptional regulator
AM462_07170	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM462_07185	COG2807	transmembrane transport
AM462_07190	COG0590	tRNA wobble adenosine to inosine editing
AM462_07200	COG0583	DNA-binding transcription factor activity
AM462_07240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM462_07240	COG2885	chlorophyll binding
AM462_07320	COG1116	anion transmembrane transporter activity
AM462_07325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM462_07335	COG0864	Transcriptional regulator
AM462_07345	COG1733	regulation of RNA biosynthetic process
AM462_07350	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM462_07355	COG0439	Biotin carboxylase
AM462_07370	COG1063	alcohol dehydrogenase
AM462_07380	COG1309	transcriptional regulator
AM462_07410	COG0038	chloride channel
AM462_07415	COG4770	biotin carboxylase activity
AM462_07435	COG1914	H( )-stimulated, divalent metal cation uptake system
AM462_07440	COG0583	DNA-binding transcription factor activity
AM462_07465	COG3209	COG3209 Rhs family protein
AM462_07480	COG3209	COG3209 Rhs family protein
AM462_07485	COG3501	Rhs element vgr protein
AM462_07515	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM462_07530	COG2826	transposase and inactivated derivatives, IS30 family
AM462_07540	COG2814	Major facilitator Superfamily
AM462_07555	COG1560	Kdo2-lipid A biosynthetic process
AM462_07565	COG5006	permease, DMT superfamily
AM462_07570	COG1522	sequence-specific DNA binding
AM462_07585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM462_07625	COG1538	Outer membrane efflux protein
AM462_07630	COG1137	ATPase activity
AM462_07635	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM462_07645	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM462_07700	COG5434	Belongs to the glycosyl hydrolase 28 family
AM462_07720	COG3566	protein conserved in bacteria
AM462_07740	COG3567	Phage-associated protein, HI1409 family
AM462_07745	COG5410	chromosome segregation
AM462_07815	COG1733	regulation of RNA biosynthetic process
AM462_07820	COG2814	Major facilitator Superfamily
AM462_07860	COG1278	Cold shock
AM462_07865	COG1280	lysine exporter protein (LysE YggA)
AM462_07900	COG1570	exodeoxyribonuclease VII activity
AM462_07955	COG0583	DNA-binding transcription factor activity
AM462_07960	COG4638	Rieske (2fe-2S)
AM462_07965	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM462_07970	COG0543	2 iron, 2 sulfur cluster binding
AM462_07970	COG0633	Ferredoxin
AM462_07975	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_07980	COG3135	benzoate transporter
AM462_07985	COG2814	Major facilitator Superfamily
AM462_08000	COG1643	Atp-dependent helicase
AM462_08005	COG0450	alkyl hydroperoxide reductase
AM462_08015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM462_08025	COG3634	alkyl hydroperoxide reductase activity
AM462_08045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM462_08050	COG0625	glutathione transferase activity
AM462_08060	COG2885	chlorophyll binding
AM462_08110	COG1765	OsmC-like protein
AM462_08120	COG0667	Aldo Keto reductase
AM462_08135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM462_08145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM462_08165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM462_08175	COG3038	cytochrome b561
AM462_08180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM462_08185	COG2252	PERMEase
AM462_08195	COG2072	flavoprotein involved in K transport
AM462_08210	COG1741	Belongs to the pirin family
AM462_08225	COG1309	transcriptional regulator
AM462_08235	COG0300	oxidoreductase activity
AM462_08240	COG2072	flavoprotein involved in K transport
AM462_08245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM462_08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_08305	COG2814	Major facilitator Superfamily
AM462_08310	COG1024	Enoyl-CoA hydratase
AM462_08315	COG1012	belongs to the aldehyde dehydrogenase family
AM462_08325	COG1960	acyl-CoA dehydrogenase activity
AM462_08350	COG2186	Transcriptional regulator
AM462_08355	COG1012	belongs to the aldehyde dehydrogenase family
AM462_08365	COG4948	Mandelate Racemase Muconate Lactonizing
AM462_08370	COG2271	Major facilitator Superfamily
AM462_08375	COG2721	sulfolactate sulfo-lyase activity
AM462_08380	COG0697	spore germination
AM462_08410	COG1113	amino acid transport
AM462_08430	COG1012	belongs to the aldehyde dehydrogenase family
AM462_08460	COG1113	amino acid transport
AM462_08500	COG3209	COG3209 Rhs family protein
AM462_08540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM462_08580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM462_08590	COG2184	nucleotidyltransferase activity
AM462_08615	COG3152	Membrane
AM462_08685	COG0582	viral genome integration into host DNA
AM462_08695	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM462_08695	COG1902	pentaerythritol trinitrate reductase activity
AM462_08705	COG5001	Diguanylate cyclase
AM462_08705	COG2203	Gaf domain
AM462_08705	COG3706	GGDEF domain
AM462_08705	COG4251	negative regulation of phosphorylation
AM462_08715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM462_08770	COG4172	Belongs to the ABC transporter superfamily
AM462_08775	COG4239	(ABC) transporter, permease
AM462_08780	COG4174	ABC transporter (Permease)
AM462_08790	COG0741	lytic transglycosylase activity
AM462_08790	COG1388	LysM domain
AM462_08790	COG0741	lytic transglycosylase activity
AM462_08790	COG1388	LysM domain
AM462_08795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM462_08835	COG0583	DNA-binding transcription factor activity
AM462_08840	COG1279	arginine transmembrane transporter activity
AM462_08860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_08865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_08870	COG0006	proline dipeptidase activity
AM462_08910	COG1278	Cold shock
AM462_08965	COG0739	heme binding
AM462_08980	COG3561	AntA/AntB antirepressor
AM462_09095	COG5410	chromosome segregation
AM462_09195	COG3620	sequence-specific DNA binding
AM462_09275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM462_09295	COG3384	dioxygenase
AM462_09305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM462_09310	COG2878	Part of a membrane complex involved in electron transport
AM462_09315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM462_09340	COG0768	penicillin binding
AM462_09345	COG0742	ribosomal rna small subunit methyltransferase
AM462_09360	COG0830	nickel cation binding
AM462_09370	COG0804	urea catabolic process
AM462_09410	COG1253	flavin adenine dinucleotide binding
AM462_09420	COG2851	Citrate transporter
AM462_09485	COG1061	Type III restriction enzyme res subunit
AM462_09505	COG1773	rubredoxin
AM462_09510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_09520	COG0583	DNA-binding transcription factor activity
AM462_09550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM462_09555	COG4181	ATPase activity
AM462_09600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM462_09620	COG0306	phosphate transporter
AM462_09630	COG3958	Transketolase
AM462_09635	COG3959	Transketolase, thiamine diphosphate binding domain
AM462_09640	COG2271	Major facilitator Superfamily
AM462_09645	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_09650	COG0583	DNA-binding transcription factor activity
AM462_09670	COG2223	nitrite transmembrane transporter activity
AM462_09675	COG2207	Transcriptional regulator
AM462_09680	COG2066	Belongs to the glutaminase family
AM462_09685	COG0242	peptide deformylase activity
AM462_09690	COG0477	Major facilitator Superfamily
AM462_09700	COG0028	Belongs to the TPP enzyme family
AM462_09715	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_09720	COG2267	carboxylic ester hydrolase activity
AM462_09730	COG2271	Major facilitator Superfamily
AM462_09735	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM462_09745	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_09765	COG1414	Transcriptional regulator
AM462_09780	COG1024	Enoyl-CoA hydratase
AM462_09790	COG1215	transferase activity, transferring glycosyl groups
AM462_09795	COG0726	polysaccharide deacetylase
AM462_09795	COG1649	PFAM Uncharacterised BCR, COG1649
AM462_09805	COG4681	YaeQ
AM462_09815	COG0523	cobalamin synthesis protein
AM462_09830	COG1061	Type III restriction enzyme res subunit
AM462_09855	COG1607	acyl-coa hydrolase
AM462_09865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_09870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_09875	COG1309	transcriptional regulator
AM462_09900	COG2040	homocysteine
AM462_09905	COG0531	amino acid
AM462_09960	COG1595	DNA-templated transcription, initiation
AM462_09970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM462_09975	COG0477	Major facilitator Superfamily
AM462_09995	COG0084	hydrolase, TatD family'
AM462_10040	COG1061	Type III restriction enzyme res subunit
AM462_10055	COG0659	secondary active sulfate transmembrane transporter activity
AM462_10060	COG0589	response to stress
AM462_10105	COG0405	Gamma-glutamyltransferase
AM462_10110	COG2814	Major facilitator Superfamily
AM462_10120	COG2050	protein possibly involved in aromatic compounds catabolism
AM462_10135	COG1090	epimerase
AM462_10155	COG0420	3'-5' exonuclease activity
AM462_10180	COG0735	belongs to the Fur family
AM462_10185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM462_10210	COG0121	glutamine amidotransferase
AM462_10225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_10235	COG0210	DNA helicase
AM462_10240	COG2885	chlorophyll binding
AM462_10245	COG0204	Acyl-transferase
AM462_10260	COG2894	cell division
AM462_10275	COG1280	lysine exporter protein (LysE YggA)
AM462_10280	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM462_10280	COG1674	ftsk spoiiie
AM462_10285	COG0492	ferredoxin-NADP+ reductase activity
AM462_10290	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM462_10300	COG0456	acetyltransferase
AM462_10360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM462_10360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM462_10380	COG1012	belongs to the aldehyde dehydrogenase family
AM462_10400	COG0473	3-isopropylmalate dehydrogenase activity
AM462_10405	COG0583	DNA-binding transcription factor activity
AM462_10425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM462_10450	COG0564	pseudouridine synthase activity
AM462_10460	COG0358	DNA primase activity
AM462_10475	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM462_10500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM462_10530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM462_10540	COG0352	thiamine-phosphate diphosphorylase activity
AM462_10540	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM462_10540	COG0351	phosphomethylpyrimidine kinase
AM462_10545	COG1652	LysM domain
AM462_10570	COG1399	metal-binding, possibly nucleic acid-binding protein
AM462_10575	COG3101	peptidyl-lysine hydroxylation
AM462_10580	COG0009	L-threonylcarbamoyladenylate synthase
AM462_10585	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AM462_10590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AM462_10605	COG4106	trans-aconitate 2-methyltransferase activity
AM462_10620	COG2226	methyltransferase
AM462_10620	COG0596	Alpha beta hydrolase
AM462_10620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM462_10625	COG1877	trehalose-phosphatase activity
AM462_10630	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM462_10635	COG2223	nitrite transmembrane transporter activity
AM462_10655	COG1196	nuclear chromosome segregation
AM462_10665	COG0730	response to heat
AM462_10680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM462_10690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM462_10750	COG0489	protein tyrosine kinase activity
AM462_10760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM462_10760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM462_10790	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AM462_10795	COG2081	HI0933 family
AM462_10805	COG0668	transmembrane transport
AM462_10825	COG0583	DNA-binding transcription factor activity
AM462_10850	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM462_10855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM462_10885	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM462_10920	COG2205	protein histidine kinase activity
AM462_10925	COG0745	RESPONSE REGULATOR receiver
AM462_10945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM462_10955	COG0384	phenazine biosynthesis protein PhzF
AM462_10985	COG1309	transcriptional regulator
AM462_10995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_11000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM462_11010	COG0583	DNA-binding transcription factor activity
AM462_11030	COG1473	amidohydrolase
AM462_11040	COG0583	DNA-binding transcription factor activity
AM462_11060	COG0583	DNA-binding transcription factor activity
AM462_11065	COG1053	succinate dehydrogenase
AM462_11075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM462_11080	COG2814	Major facilitator Superfamily
AM462_11085	COG1960	acyl-CoA dehydrogenase activity
AM462_11090	COG0583	DNA-binding transcription factor activity
AM462_11095	COG1063	alcohol dehydrogenase
AM462_11130	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM462_11135	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AM462_11140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM462_11155	COG3667	copper resistance
AM462_11160	COG2132	Multicopper oxidase
AM462_11170	COG0561	phosphatase activity
AM462_11175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM462_11185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM462_11200	COG1214	PFAM Peptidase M22, glycoprotease
AM462_11250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM462_11260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM462_11265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM462_11270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM462_11330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM462_11340	COG1846	Transcriptional regulator
AM462_11345	COG1764	response to oxidative stress
AM462_11385	COG0037	tRNA processing
AM462_11395	COG0248	Ppx GppA phosphatase
AM462_11425	COG0072	phenylalanine-tRNA ligase activity
AM462_11445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM462_11460	COG1238	metal cluster binding
AM462_11465	COG0625	glutathione transferase activity
AM462_11480	COG0318	PFAM AMP-dependent synthetase and ligase
AM462_11485	COG3028	Belongs to the UPF0307 family
AM462_11490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM462_11510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM462_11515	COG0617	tRNA 3'-terminal CCA addition
AM462_11520	COG1555	photosystem II stabilization
AM462_11525	COG3956	TIGRFAM MazG family protein
AM462_11535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM462_11555	COG5002	protein histidine kinase activity
AM462_11555	COG2205	protein histidine kinase activity
AM462_11555	COG0784	Response regulator, receiver
AM462_11560	COG1024	Enoyl-CoA hydratase
AM462_11565	COG2084	Dehydrogenase
AM462_11570	COG3622	Belongs to the hyi family
AM462_11585	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM462_11590	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM462_11595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM462_11600	COG0697	spore germination
AM462_11610	COG2814	Major facilitator Superfamily
AM462_11630	COG2132	Multicopper oxidase
AM462_11645	COG2205	protein histidine kinase activity
AM462_11735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM462_11745	COG0583	DNA-binding transcription factor activity
AM462_11755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM462_11765	COG0084	hydrolase, TatD family'
AM462_11780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM462_11790	COG2826	transposase and inactivated derivatives, IS30 family
AM462_11825	COG0440	acetolactate synthase activity
AM462_11830	COG0028	Belongs to the TPP enzyme family
AM462_11855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_11860	COG0577	efflux transmembrane transporter activity
AM462_11860	COG1136	(ABC) transporter
AM462_11865	COG1538	Outer membrane efflux protein
AM462_11880	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM462_11885	COG1162	GTPase activity
AM462_11895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM462_11935	COG1426	Protein conserved in bacteria
AM462_11970	COG0793	Belongs to the peptidase S41A family
AM462_11985	COG2267	carboxylic ester hydrolase activity
AM462_11995	COG1012	belongs to the aldehyde dehydrogenase family
AM462_12000	COG3265	gluconokinase activity
AM462_12010	COG0800	Aldolase
AM462_12020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM462_12025	COG0857	belongs to the CobB CobQ family
AM462_12025	COG0280	phosphate acetyltransferase
AM462_12030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM462_12030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM462_12050	COG0740	serine-type endopeptidase activity
AM462_12060	COG4774	siderophore transport
AM462_12070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM462_12080	COG2813	Specifically methylates the guanine in position
AM462_12080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM462_12180	COG0788	formyltetrahydrofolate deformylase activity
AM462_12195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM462_12200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM462_12205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM462_12205	COG4651	solute:proton antiporter activity
AM462_12225	COG0724	RNA recognition motif
AM462_12230	COG0210	DNA helicase
AM462_12255	COG1733	regulation of RNA biosynthetic process
AM462_12275	COG1280	lysine exporter protein (LysE YggA)
AM462_12280	COG1560	Kdo2-lipid A biosynthetic process
AM462_12290	COG1301	dicarboxylic acid transport
AM462_12345	COG0473	3-isopropylmalate dehydrogenase activity
AM462_12400	COG0583	DNA-binding transcription factor activity
AM462_12410	COG0625	glutathione transferase activity
AM462_12415	COG2378	regulation of single-species biofilm formation
AM462_12420	COG0546	phosphoglycolate phosphatase activity
AM462_12435	COG1530	ribonuclease E activity
AM462_12455	COG0583	DNA-binding transcription factor activity
AM462_12460	COG4221	oxidoreductase activity
AM462_12465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM462_12475	COG0534	Mate efflux family protein
AM462_12490	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM462_12525	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM462_12530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_12545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM462_12555	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM462_12555	COG0644	oxidoreductase
AM462_12565	COG0425	Belongs to the sulfur carrier protein TusA family
AM462_12570	COG4535	Mg2 and Co2 transporter CorC
AM462_12580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM462_12600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM462_12605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM462_12605	COG0475	glutathione-regulated potassium exporter activity
AM462_12620	COG0484	heat shock protein binding
AM462_12625	COG0789	Transcriptional regulator
AM462_12630	COG0598	Magnesium transport protein CorA
AM462_12650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM462_12655	COG1074	ATP-dependent DNA helicase activity
AM462_12660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM462_12680	COG2226	methyltransferase
AM462_12695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_12700	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM462_12715	COG2111	Na H antiporter
AM462_12715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM462_12720	COG1006	Multisubunit Na H antiporter MnhC subunit
AM462_12725	COG0651	ATP synthesis coupled electron transport
AM462_12735	COG2212	antiporter activity
AM462_12755	COG0195	Participates in both transcription termination and antitermination
AM462_12805	COG0237	dephospho-CoA kinase activity
AM462_12815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM462_12830	COG0497	DNA recombination
AM462_12840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM462_12870	COG2169	Transcriptional regulator
AM462_12870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM462_12875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM462_12935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AM462_12950	COG0326	Molecular chaperone. Has ATPase activity
AM462_12965	COG2056	Na+-H+ antiporter family
AM462_13065	COG0546	phosphoglycolate phosphatase activity
AM462_13070	COG1716	ATPase activity
AM462_13115	COG0181	hydroxymethylbilane synthase activity
AM462_13125	COG3275	phosphorelay sensor kinase activity
AM462_13145	COG1538	Outer membrane efflux protein
AM462_13150	COG0697	spore germination
AM462_13175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM462_13180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM462_13185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM462_13190	COG0772	Belongs to the SEDS family
AM462_13215	COG4974	Belongs to the 'phage' integrase family
AM462_13220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM462_13230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM462_13240	COG2197	response regulator
AM462_13255	COG0793	Belongs to the peptidase S41A family
AM462_13260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM462_13265	COG0795	lipopolysaccharide-transporting ATPase activity
AM462_13305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM462_13305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM462_13315	COG0004	ammonium transporteR
AM462_13320	COG0347	Belongs to the P(II) protein family
AM462_13330	COG0606	chelatase, subunit chli
AM462_13340	COG0659	secondary active sulfate transmembrane transporter activity
AM462_13370	COG0789	Transcriptional regulator
AM462_13445	COG3316	Transposase and inactivated derivatives
AM462_13465	COG3316	Transposase and inactivated derivatives
AM462_13470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM462_13485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM462_13500	COG0318	PFAM AMP-dependent synthetase and ligase
AM462_13510	COG0477	Major facilitator Superfamily
AM462_13515	COG2860	membrane
AM462_13520	COG3012	SEC-C Motif Domain Protein
AM462_13525	COG1253	flavin adenine dinucleotide binding
AM462_13535	COG2814	Major facilitator Superfamily
AM462_13545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM462_13590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM462_13625	COG1309	transcriptional regulator
AM462_13660	COG0758	DNA mediated transformation
AM462_13670	COG0697	spore germination
AM462_13675	COG1309	transcriptional regulator
AM462_13690	COG0386	Belongs to the glutathione peroxidase family
AM462_13755	COG1121	(ABC) transporter
AM462_13760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM462_13765	COG1280	lysine exporter protein (LysE YggA)
AM462_13770	COG2837	iron assimilation
AM462_13775	COG0281	malic enzyme
AM462_13820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM462_13820	COG0519	Catalyzes the synthesis of GMP from XMP
AM462_13825	COG4399	Belongs to the UPF0754 family
AM462_13830	COG2259	Doxx family
AM462_13835	COG0586	Pfam SNARE associated Golgi protein
AM462_13850	COG1192	Involved in chromosome partitioning
AM462_13860	COG0271	Belongs to the BolA IbaG family
AM462_13895	COG3756	Protein conserved in bacteria
AM462_13990	COG0642	Histidine kinase
AM462_13995	COG0745	RESPONSE REGULATOR receiver
AM462_14000	COG2194	sulfuric ester hydrolase activity
AM462_14010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM462_14015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM462_14030	COG1570	exodeoxyribonuclease VII activity
AM462_14055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM462_14060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM462_14070	COG0659	secondary active sulfate transmembrane transporter activity
AM462_14090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_14105	COG3316	Transposase and inactivated derivatives
AM462_14125	COG2826	transposase and inactivated derivatives, IS30 family
AM462_14155	COG1324	tolerance protein
AM462_14160	COG0673	inositol 2-dehydrogenase activity
AM462_14180	COG2826	transposase and inactivated derivatives, IS30 family
AM462_14220	COG3316	Transposase and inactivated derivatives
AM462_14230	COG2267	carboxylic ester hydrolase activity
AM462_14250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM462_14250	COG3321	synthase
AM462_14250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM462_14250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM462_14255	COG1960	acyl-CoA dehydrogenase activity
AM462_14265	COG2197	response regulator
AM462_14275	COG3916	Acyl-homoserine-lactone synthase
AM462_14280	COG0477	Major facilitator Superfamily
AM462_14285	COG1024	Enoyl-CoA hydratase
AM462_14290	COG1024	Enoyl-CoA hydratase
AM462_14295	COG1960	acyl-CoA dehydrogenase activity
AM462_14300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM462_14320	COG1113	amino acid transport
AM462_14325	COG1113	amino acid transport
AM462_14330	COG0251	oxidation-reduction process
AM462_14345	COG1522	sequence-specific DNA binding
AM462_14370	COG0564	pseudouridine synthase activity
AM462_14420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM462_14435	COG1802	Transcriptional regulator
AM462_14440	COG1448	Aminotransferase
AM462_14445	COG0277	FAD linked oxidase domain protein
AM462_14455	COG2186	Transcriptional regulator
AM462_14465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_14480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM462_14490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM462_14500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM462_14505	COG0438	transferase activity, transferring glycosyl groups
AM462_14515	COG0438	transferase activity, transferring glycosyl groups
AM462_14535	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM462_14565	COG0728	peptidoglycan biosynthetic process
AM462_14570	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM462_14630	COG0546	phosphoglycolate phosphatase activity
AM462_14635	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_14655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM462_14660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM462_14665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM462_14670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM462_14675	COG1116	anion transmembrane transporter activity
AM462_14680	COG1309	transcriptional regulator
AM462_14685	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM462_14695	COG0196	riboflavin kinase activity
AM462_14700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM462_14710	COG1047	Peptidyl-prolyl cis-trans
AM462_14750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM462_14805	COG2951	lytic endotransglycosylase activity
AM462_14810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM462_14830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM462_14840	COG0671	phosphoesterase, PA-phosphatase related
AM462_14845	COG0861	Integral membrane protein TerC family
AM462_14855	COG0754	glutathionylspermidine amidase activity
AM462_14865	COG0402	S-adenosylhomocysteine deaminase activity
AM462_14880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM462_14885	COG1230	cation diffusion facilitator family transporter
AM462_14900	COG0706	membrane insertase activity
AM462_14915	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AM462_14925	COG0592	DNA-directed DNA polymerase activity
AM462_14935	COG0187	DNA topoisomerase II activity
AM462_14945	COG0586	Pfam SNARE associated Golgi protein
AM462_14950	COG0488	(ABC) transporter
AM462_14975	COG0596	Alpha beta hydrolase
AM462_14980	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM462_14985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM462_15030	COG0733	neurotransmitter:sodium symporter activity
AM462_15065	COG0583	DNA-binding transcription factor activity
AM462_15070	COG2233	PERMEase
AM462_15085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_15120	COG2814	Major facilitator Superfamily
AM462_15125	COG0656	L-ascorbic acid biosynthetic process
AM462_15130	COG0583	DNA-binding transcription factor activity
AM462_15145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM462_15150	COG1064	alcohol dehydrogenase
AM462_15155	COG2818	Glycosylase
AM462_15170	COG1194	a g-specific adenine glycosylase
AM462_15190	COG2983	Belongs to the UPF0260 family
AM462_15195	COG2133	pyrroloquinoline quinone binding
AM462_15200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM462_15205	COG2116	formate transmembrane transporter activity
AM462_15225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM462_15230	COG1335	isochorismatase
AM462_15235	COG0385	Bile acid
AM462_15240	COG0534	Mate efflux family protein
AM462_15245	COG1683	Conserved Protein
AM462_15265	COG0625	glutathione transferase activity
AM462_15275	COG1113	amino acid transport
AM462_15285	COG0523	cobalamin synthesis protein
AM462_15295	COG2188	Transcriptional regulator
AM462_15325	COG0010	Belongs to the arginase family
AM462_15340	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM462_15380	COG0589	response to stress
AM462_15385	COG0659	secondary active sulfate transmembrane transporter activity
AM462_15415	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM462_15470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_15520	COG3316	Transposase and inactivated derivatives
AM462_15535	COG3173	Aminoglycoside phosphotransferase
AM462_15555	COG0482	sulfurtransferase activity
AM462_15645	COG3316	Transposase and inactivated derivatives
AM462_15710	COG1192	Involved in chromosome partitioning
AM462_15730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_15835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM462_15845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM462_15850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM462_15940	COG0534	Mate efflux family protein
AM462_15945	COG0436	Aminotransferase
AM462_15950	COG2733	membrane
AM462_15965	COG2918	glutathione biosynthetic process
AM462_15975	COG3501	Rhs element vgr protein
AM462_15980	COG1388	LysM domain
AM462_15980	COG3409	Peptidoglycan-binding domain 1 protein
AM462_15980	COG5632	N-Acetylmuramoyl-L-alanine amidase
AM462_16010	COG3150	esterase
AM462_16020	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AM462_16030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_16040	COG2233	PERMEase
AM462_16045	COG2351	hydroxyisourate hydrolase activity
AM462_16080	COG3706	GGDEF domain
AM462_16095	COG1393	Belongs to the ArsC family
AM462_16100	COG0708	Exodeoxyribonuclease III
AM462_16120	COG0189	ligase activity
AM462_16140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM462_16150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM462_16165	COG4942	peptidase
AM462_16175	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM462_16185	COG2119	membrane
AM462_16190	COG4774	siderophore transport
AM462_16195	COG0426	domain, Protein
AM462_16195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_16220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM462_16240	COG1902	pentaerythritol trinitrate reductase activity
AM462_16245	COG1519	Transferase
AM462_16250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM462_16255	COG0668	transmembrane transport
AM462_16265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM462_16270	COG1335	isochorismatase
AM462_16275	COG1522	sequence-specific DNA binding
AM462_16300	COG2205	protein histidine kinase activity
AM462_16300	COG0784	Response regulator, receiver
AM462_16300	COG2198	Histidine kinase
AM462_16305	COG3162	membrane
AM462_16310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM462_16320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_16330	COG3706	GGDEF domain
AM462_16335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM462_16340	COG1309	transcriptional regulator
AM462_16360	COG0351	phosphomethylpyrimidine kinase
AM462_16360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM462_16360	COG0352	thiamine-phosphate diphosphorylase activity
AM462_16370	COG2814	Major facilitator Superfamily
AM462_16385	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM462_16395	COG1113	amino acid transport
AM462_16405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM462_16410	COG1012	belongs to the aldehyde dehydrogenase family
AM462_16420	COG1335	isochorismatase
AM462_16450	COG2814	Major facilitator Superfamily
AM462_16455	COG0583	DNA-binding transcription factor activity
AM462_16475	COG0667	Aldo Keto reductase
AM462_16500	COG1733	regulation of RNA biosynthetic process
AM462_16515	COG1733	regulation of RNA biosynthetic process
AM462_16525	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM462_16535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM462_16595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM462_16635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM462_16665	COG0427	acetyl-CoA hydrolase
AM462_16680	COG0745	RESPONSE REGULATOR receiver
AM462_16690	COG0659	secondary active sulfate transmembrane transporter activity
AM462_16695	COG4221	oxidoreductase activity
AM462_16705	COG0488	(ABC) transporter
AM462_16770	COG0833	amino acid
AM462_16815	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM462_16820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM462_16835	COG2226	methyltransferase
AM462_16885	COG0070	glutamate synthase
AM462_16885	COG0069	glutamate synthase activity
AM462_16885	COG0067	glutamate synthase
AM462_16890	COG0493	'glutamate synthase
AM462_16900	COG1704	LemA family
AM462_16905	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM462_16920	COG3307	-O-antigen
AM462_16940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM462_16955	COG0194	GDP metabolic process
AM462_17005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM462_17025	COG5380	lipid catabolic process
AM462_17030	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM462_17055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM462_17060	COG0277	FAD linked oxidase domain protein
AM462_17070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM462_17075	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM462_17090	COG1289	transmembrane transporter activity
AM462_17100	COG0628	permease
AM462_17105	COG1192	Involved in chromosome partitioning
AM462_17135	COG0833	amino acid
AM462_17140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM462_17145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM462_17155	COG1012	belongs to the aldehyde dehydrogenase family
AM462_17195	COG0583	DNA-binding transcription factor activity
AM462_17245	COG0517	IMP dehydrogenase activity
AM462_17250	COG1983	PspC domain protein
AM462_17270	COG1960	acyl-CoA dehydrogenase activity
AM462_17285	COG0408	coproporphyrinogen oxidase activity
AM462_17305	COG0513	Belongs to the DEAD box helicase family
AM462_17310	COG1127	ABC transporter
AM462_17315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM462_17325	COG2854	intermembrane phospholipid transfer
AM462_17335	COG0598	Magnesium transport protein CorA
AM462_17345	COG0494	nUDIX hydrolase
AM462_17350	COG1040	competence protein
AM462_17355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM462_17375	COG1946	Acyl-CoA thioesterase
AM462_17380	COG1301	dicarboxylic acid transport
AM462_17395	COG1959	2 iron, 2 sulfur cluster binding
AM462_17400	COG1017	nitric oxide dioxygenase activity
AM462_17400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_17405	COG0433	COG0433 Predicted ATPase
AM462_17410	COG0626	cystathionine gamma-synthase activity
AM462_17530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM462_17540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM462_17565	COG1960	acyl-CoA dehydrogenase activity
AM462_17570	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM462_17600	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM462_17605	COG0339	signal peptide processing
AM462_17610	COG0557	exoribonuclease II activity
AM462_17655	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM462_17660	COG2169	Transcriptional regulator
AM462_17665	COG0697	spore germination
AM462_17670	COG1295	ribonuclease BN
AM462_17705	COG1702	phosphate starvation-inducible protein PhoH
AM462_17715	COG0739	heme binding
AM462_17715	COG0741	lytic transglycosylase activity
AM462_17715	COG1196	nuclear chromosome segregation
AM462_17745	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM462_17750	COG1183	phosphatidylcholine synthase activity
AM462_17795	COG1960	acyl-CoA dehydrogenase activity
AM462_17800	COG1309	transcriptional regulator
AM462_17815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM462_17820	COG1960	acyl-CoA dehydrogenase activity
AM462_17840	COG2969	positive regulation of protein catabolic process
AM462_17850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM462_17865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM462_17870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM462_17890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM462_17900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM462_17905	COG1408	metallophosphoesterase
AM462_17915	COG2199	diguanylate cyclase activity
AM462_17960	COG3453	Protein conserved in bacteria
AM462_17960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_17975	COG1607	acyl-coa hydrolase
AM462_18005	COG2350	Protein conserved in bacteria
AM462_18015	COG0613	PHP domain protein
AM462_18020	COG3781	membrane
AM462_18030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM462_18045	COG1862	Preprotein translocase
AM462_18075	COG2205	protein histidine kinase activity
AM462_18080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM462_18100	COG0726	polysaccharide deacetylase
AM462_18105	COG0463	Glycosyl transferase, family 2
AM462_18110	COG0438	transferase activity, transferring glycosyl groups
AM462_18175	COG1960	acyl-CoA dehydrogenase activity
AM462_18180	COG1960	acyl-CoA dehydrogenase activity
AM462_18190	COG2205	protein histidine kinase activity
AM462_18195	COG0745	RESPONSE REGULATOR receiver
AM462_18200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AM462_18220	COG2096	Adenosyltransferase
AM462_18235	COG0133	tryptophan synthase activity
AM462_18270	COG0285	dihydrofolate synthase activity
AM462_18290	COG0450	alkyl hydroperoxide reductase
AM462_18305	COG0477	Major facilitator Superfamily
AM462_18310	COG1272	protein, Hemolysin III
AM462_18320	COG2153	protein acetylation
AM462_18340	COG0183	Belongs to the thiolase family
AM462_18345	COG2207	Transcriptional regulator
AM462_18365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_18395	COG2885	chlorophyll binding
AM462_18395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM462_18400	COG1690	Belongs to the RtcB family
AM462_18405	COG0833	amino acid
AM462_18415	COG2233	PERMEase
AM462_18445	COG2094	Belongs to the DNA glycosylase MPG family
AM462_18450	COG4772	TonB-dependent receptor
AM462_18455	COG1902	pentaerythritol trinitrate reductase activity
AM462_18460	COG0679	Auxin Efflux Carrier
AM462_18470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM462_18475	COG0354	folic acid binding
AM462_18485	COG3189	MarR family transcriptional regulator
AM462_18490	COG2824	Alkylphosphonate utilization operon protein PhnA
AM462_18495	COG3422	double-strand break repair
AM462_18535	COG0840	transmembrane signaling receptor activity
AM462_18550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM462_18560	COG2826	transposase and inactivated derivatives, IS30 family
AM462_18575	COG5510	response to toxic substance
AM462_18585	COG2832	Protein of unknown function (DUF454)
AM462_18590	COG1376	ErfK ybiS ycfS ynhG family protein
AM462_18640	COG1289	transmembrane transporter activity
AM462_18645	COG2814	Major facilitator Superfamily
AM462_18665	COG1115	amino acid carrier protein
AM462_18670	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM462_18675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM462_18680	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM462_18705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM462_18715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM462_18720	COG1077	Cell shape determining protein MreB Mrl
AM462_18725	COG1792	Involved in formation and maintenance of cell shape
AM462_18730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM462_18735	COG0424	maF-like protein
AM462_18740	COG1530	ribonuclease E activity
AM462_18750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM462_18770	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM462_18795	COG2207	Transcriptional regulator
AM462_18850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM462_18855	COG4197	protein conserved in bacteria, prophage-related
AM462_18885	COG0305	Participates in initiation and elongation during chromosome replication
AM462_18910	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM462_18965	COG4626	Terminase
AM462_18965	COG1802	Transcriptional regulator
AM462_18970	COG4695	Portal protein
AM462_18975	COG0740	serine-type endopeptidase activity
AM462_19030	COG0741	lytic transglycosylase activity
AM462_19030	COG0739	heme binding
AM462_19030	COG1196	nuclear chromosome segregation
AM462_19090	COG1113	amino acid transport
AM462_19095	COG2828	Protein conserved in bacteria
AM462_19100	COG0142	geranyltranstransferase activity
AM462_19105	COG2315	Protein conserved in bacteria
AM462_19120	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM462_19140	COG2194	sulfuric ester hydrolase activity
AM462_19145	COG0745	RESPONSE REGULATOR receiver
AM462_19150	COG0642	Histidine kinase
AM462_19160	COG0004	ammonium transporteR
AM462_19170	COG0583	DNA-binding transcription factor activity
AM462_19190	COG0525	valine-tRNA ligase activity
AM462_19200	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_19210	COG0393	Putative heavy-metal-binding
AM462_19215	COG0393	Putative heavy-metal-binding
AM462_19220	COG1538	Outer membrane efflux protein
AM462_19230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_19235	COG0671	phosphoesterase, PA-phosphatase related
AM462_19265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM462_19280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM462_19280	COG1648	precorrin-2 dehydrogenase activity
AM462_19285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM462_19290	COG1733	regulation of RNA biosynthetic process
AM462_19300	COG0531	amino acid
AM462_19315	COG0321	lipoyl(octanoyl) transferase activity
AM462_19320	COG2921	Belongs to the UPF0250 family
AM462_19355	COG2009	succinate dehydrogenase
AM462_19360	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM462_19365	COG1053	succinate dehydrogenase
AM462_19370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM462_19395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM462_19425	COG2354	Protein conserved in bacteria
AM462_19430	COG2321	neutral zinc metallopeptidase
AM462_19450	COG2843	Capsule synthesis protein
AM462_19465	COG0589	response to stress
AM462_19485	COG0505	Belongs to the CarA family
AM462_19510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM462_19515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM462_19565	COG0477	Major facilitator Superfamily
AM462_19570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM462_19590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM462_19615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_19620	COG0584	glycerophosphoryl diester phosphodiesterase
AM462_19640	COG0741	lytic transglycosylase activity
AM462_19665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM462_19680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM462_19720	COG0778	Nitroreductase
AM462_19735	COG1929	Belongs to the glycerate kinase type-1 family
AM462_19740	COG0243	molybdopterin cofactor binding
AM462_19745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM462_19750	COG3339	Conserved Protein
AM462_19760	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM462_19775	COG1113	amino acid transport
AM462_19785	COG0019	diaminopimelate decarboxylase activity
AM462_19795	COG2267	carboxylic ester hydrolase activity
AM462_19800	COG1280	lysine exporter protein (LysE YggA)
AM462_19805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM462_19835	COG0463	Glycosyl transferase, family 2
AM462_19855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_19890	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM462_19895	COG1136	(ABC) transporter
AM462_19900	COG0658	competence protein
AM462_19900	COG2333	competence protein COMEC
AM462_19910	COG0616	signal peptide processing
AM462_19910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM462_19915	COG0596	Alpha beta hydrolase
AM462_19920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM462_19930	COG0628	permease
AM462_19970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM462_19990	COG0823	Involved in the tonB-independent uptake of proteins
AM462_20010	COG0824	Thioesterase
AM462_20015	COG1473	amidohydrolase
AM462_20035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM462_20035	COG0047	phosphoribosylformylglycinamidine synthase activity
AM462_20040	COG2814	Major facilitator Superfamily
AM462_20045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM462_20050	COG1024	Enoyl-CoA hydratase
AM462_20055	COG1056	cytidyltransferase-related domain
AM462_20055	COG1051	belongs to the nudix hydrolase family
AM462_20065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM462_20080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM462_20095	COG4625	pathogenesis
AM462_20100	COG0583	DNA-binding transcription factor activity
AM462_20105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM462_20110	COG4208	sulfate ABC transporter
AM462_20115	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM462_20125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM462_20130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM462_20135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM462_20155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM462_20170	COG0681	Belongs to the peptidase S26 family
AM462_20185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM462_20195	COG1381	Involved in DNA repair and RecF pathway recombination
AM462_20200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM462_20210	COG4221	oxidoreductase activity
AM462_20260	COG0556	nucleotide-excision repair