locus-tag	class	description
ACX60_00010	COG0592	DNA-directed DNA polymerase activity
ACX60_00020	COG0187	DNA topoisomerase II activity
ACX60_00030	COG0586	Pfam SNARE associated Golgi protein
ACX60_00035	COG0488	(ABC) transporter
ACX60_00060	COG0596	Alpha beta hydrolase
ACX60_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACX60_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACX60_00110	COG0733	neurotransmitter:sodium symporter activity
ACX60_00150	COG2233	PERMEase
ACX60_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_00200	COG2814	Major facilitator Superfamily
ACX60_00205	COG0656	L-ascorbic acid biosynthetic process
ACX60_00210	COG0583	DNA-binding transcription factor activity
ACX60_00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_00225	COG1064	alcohol dehydrogenase
ACX60_00230	COG2818	Glycosylase
ACX60_00245	COG1194	a g-specific adenine glycosylase
ACX60_00265	COG2983	Belongs to the UPF0260 family
ACX60_00270	COG2133	pyrroloquinoline quinone binding
ACX60_00275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACX60_00280	COG2116	formate transmembrane transporter activity
ACX60_00300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX60_00305	COG1335	isochorismatase
ACX60_00310	COG0385	Bile acid
ACX60_00315	COG0534	Mate efflux family protein
ACX60_00320	COG1683	Conserved Protein
ACX60_00340	COG0625	glutathione transferase activity
ACX60_00350	COG1113	amino acid transport
ACX60_00360	COG0523	cobalamin synthesis protein
ACX60_00370	COG2188	Transcriptional regulator
ACX60_00400	COG0010	Belongs to the arginase family
ACX60_00420	COG1280	lysine exporter protein (LysE YggA)
ACX60_00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACX60_00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACX60_00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACX60_00500	COG0753	catalase activity
ACX60_00550	COG0534	Mate efflux family protein
ACX60_00555	COG0436	Aminotransferase
ACX60_00560	COG2733	membrane
ACX60_00575	COG2918	glutathione biosynthetic process
ACX60_00605	COG1388	LysM domain
ACX60_00605	COG1705	Flagellar rod assembly protein muramidase FlgJ
ACX60_00645	COG3150	esterase
ACX60_00655	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ACX60_00665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX60_00675	COG2233	PERMEase
ACX60_00680	COG2351	hydroxyisourate hydrolase activity
ACX60_00715	COG3706	GGDEF domain
ACX60_00730	COG1393	Belongs to the ArsC family
ACX60_00735	COG0708	Exodeoxyribonuclease III
ACX60_00760	COG0189	ligase activity
ACX60_00780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACX60_00790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACX60_00805	COG4942	peptidase
ACX60_00815	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACX60_00825	COG2119	membrane
ACX60_00830	COG4774	siderophore transport
ACX60_00835	COG0426	domain, Protein
ACX60_00835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_00860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACX60_00880	COG1902	pentaerythritol trinitrate reductase activity
ACX60_00885	COG1519	Transferase
ACX60_00895	COG0668	transmembrane transport
ACX60_00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX60_00910	COG1335	isochorismatase
ACX60_00915	COG1522	sequence-specific DNA binding
ACX60_00940	COG0784	Response regulator, receiver
ACX60_00940	COG2198	Histidine kinase
ACX60_00940	COG2205	protein histidine kinase activity
ACX60_00945	COG3162	membrane
ACX60_00950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACX60_00960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX60_00970	COG3706	GGDEF domain
ACX60_00975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACX60_00980	COG1309	transcriptional regulator
ACX60_01000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACX60_01000	COG0352	thiamine-phosphate diphosphorylase activity
ACX60_01000	COG0351	phosphomethylpyrimidine kinase
ACX60_01010	COG2814	Major facilitator Superfamily
ACX60_01025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACX60_01035	COG1113	amino acid transport
ACX60_01045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACX60_01050	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_01060	COG1335	isochorismatase
ACX60_01095	COG2814	Major facilitator Superfamily
ACX60_01100	COG0583	DNA-binding transcription factor activity
ACX60_01145	COG1733	regulation of RNA biosynthetic process
ACX60_01175	COG1733	regulation of RNA biosynthetic process
ACX60_01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_01200	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACX60_01205	COG2207	Transcriptional regulator
ACX60_01260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACX60_01275	COG2329	Antibiotic biosynthesis monooxygenase
ACX60_01305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACX60_01335	COG0427	acetyl-CoA hydrolase
ACX60_01345	COG0745	RESPONSE REGULATOR receiver
ACX60_01355	COG0659	secondary active sulfate transmembrane transporter activity
ACX60_01360	COG4221	oxidoreductase activity
ACX60_01385	COG0488	(ABC) transporter
ACX60_01450	COG0833	amino acid
ACX60_01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACX60_01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACX60_01515	COG2226	methyltransferase
ACX60_01565	COG0069	glutamate synthase activity
ACX60_01565	COG0067	glutamate synthase
ACX60_01565	COG0070	glutamate synthase
ACX60_01570	COG0493	'glutamate synthase
ACX60_01580	COG1704	LemA family
ACX60_01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACX60_01600	COG3307	-O-antigen
ACX60_01620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACX60_01630	COG0194	GDP metabolic process
ACX60_01680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACX60_01700	COG5380	lipid catabolic process
ACX60_01705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACX60_01730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACX60_01735	COG0277	FAD linked oxidase domain protein
ACX60_01745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACX60_01750	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_01765	COG1289	transmembrane transporter activity
ACX60_01775	COG0628	permease
ACX60_01780	COG1192	Involved in chromosome partitioning
ACX60_01810	COG0833	amino acid
ACX60_01815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACX60_01820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACX60_01830	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_01870	COG0583	DNA-binding transcription factor activity
ACX60_01920	COG0517	IMP dehydrogenase activity
ACX60_01925	COG1983	PspC domain protein
ACX60_01935	COG1960	acyl-CoA dehydrogenase activity
ACX60_01950	COG0408	coproporphyrinogen oxidase activity
ACX60_01970	COG0513	Belongs to the DEAD box helicase family
ACX60_01980	COG1127	ABC transporter
ACX60_01985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACX60_01995	COG2854	intermembrane phospholipid transfer
ACX60_02005	COG0598	Magnesium transport protein CorA
ACX60_02015	COG0494	nUDIX hydrolase
ACX60_02020	COG1040	competence protein
ACX60_02025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACX60_02045	COG1946	Acyl-CoA thioesterase
ACX60_02050	COG1301	dicarboxylic acid transport
ACX60_02065	COG1959	2 iron, 2 sulfur cluster binding
ACX60_02070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_02070	COG1017	nitric oxide dioxygenase activity
ACX60_02075	COG0433	COG0433 Predicted ATPase
ACX60_02080	COG0626	cystathionine gamma-synthase activity
ACX60_02200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACX60_02210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACX60_02235	COG1960	acyl-CoA dehydrogenase activity
ACX60_02240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACX60_02270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ACX60_02275	COG0339	signal peptide processing
ACX60_02280	COG0557	exoribonuclease II activity
ACX60_02325	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACX60_02330	COG2169	Transcriptional regulator
ACX60_02335	COG0697	spore germination
ACX60_02340	COG1295	ribonuclease BN
ACX60_02375	COG1702	phosphate starvation-inducible protein PhoH
ACX60_02385	COG0741	lytic transglycosylase activity
ACX60_02385	COG0739	heme binding
ACX60_02385	COG1196	nuclear chromosome segregation
ACX60_02415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACX60_02420	COG1183	phosphatidylcholine synthase activity
ACX60_02465	COG1960	acyl-CoA dehydrogenase activity
ACX60_02470	COG1309	transcriptional regulator
ACX60_02485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACX60_02490	COG1960	acyl-CoA dehydrogenase activity
ACX60_02510	COG2969	positive regulation of protein catabolic process
ACX60_02520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACX60_02530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACX60_02535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACX60_02540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACX60_02560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACX60_02570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACX60_02575	COG1408	metallophosphoesterase
ACX60_02585	COG2199	diguanylate cyclase activity
ACX60_02630	COG3453	Protein conserved in bacteria
ACX60_02630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_02645	COG1607	acyl-coa hydrolase
ACX60_02680	COG3013	Belongs to the UPF0304 family
ACX60_02755	COG2205	protein histidine kinase activity
ACX60_02770	COG2132	Multicopper oxidase
ACX60_02795	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACX60_02840	COG0582	viral genome integration into host DNA
ACX60_02865	COG2350	Protein conserved in bacteria
ACX60_02875	COG0613	PHP domain protein
ACX60_02880	COG3781	membrane
ACX60_02890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACX60_02895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACX60_02905	COG1862	Preprotein translocase
ACX60_02935	COG0582	viral genome integration into host DNA
ACX60_02975	COG2205	protein histidine kinase activity
ACX60_02980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACX60_03000	COG0726	polysaccharide deacetylase
ACX60_03005	COG0463	Glycosyl transferase, family 2
ACX60_03010	COG0438	transferase activity, transferring glycosyl groups
ACX60_03025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACX60_03075	COG1960	acyl-CoA dehydrogenase activity
ACX60_03080	COG1960	acyl-CoA dehydrogenase activity
ACX60_03090	COG2205	protein histidine kinase activity
ACX60_03095	COG0745	RESPONSE REGULATOR receiver
ACX60_03100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACX60_03120	COG2096	Adenosyltransferase
ACX60_03125	COG4206	TonB-dependent receptor
ACX60_03135	COG0133	tryptophan synthase activity
ACX60_03170	COG0285	dihydrofolate synthase activity
ACX60_03190	COG0450	alkyl hydroperoxide reductase
ACX60_03205	COG0477	Major facilitator Superfamily
ACX60_03210	COG1272	protein, Hemolysin III
ACX60_03220	COG2153	protein acetylation
ACX60_03240	COG0183	Belongs to the thiolase family
ACX60_03245	COG2207	Transcriptional regulator
ACX60_03265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX60_03285	COG0183	Belongs to the thiolase family
ACX60_03305	COG1690	Belongs to the RtcB family
ACX60_03310	COG0833	amino acid
ACX60_03320	COG2233	PERMEase
ACX60_03350	COG2094	Belongs to the DNA glycosylase MPG family
ACX60_03355	COG4772	TonB-dependent receptor
ACX60_03360	COG1902	pentaerythritol trinitrate reductase activity
ACX60_03365	COG0679	Auxin Efflux Carrier
ACX60_03375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX60_03380	COG0354	folic acid binding
ACX60_03390	COG3189	MarR family transcriptional regulator
ACX60_03395	COG2824	Alkylphosphonate utilization operon protein PhnA
ACX60_03400	COG3422	double-strand break repair
ACX60_03440	COG0840	transmembrane signaling receptor activity
ACX60_03460	COG5510	response to toxic substance
ACX60_03470	COG2832	Protein of unknown function (DUF454)
ACX60_03475	COG1376	ErfK ybiS ycfS ynhG family protein
ACX60_03525	COG1289	transmembrane transporter activity
ACX60_03530	COG2814	Major facilitator Superfamily
ACX60_03545	COG1115	amino acid carrier protein
ACX60_03550	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACX60_03555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACX60_03560	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ACX60_03565	COG3590	peptidase
ACX60_03590	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACX60_03600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACX60_03605	COG1077	Cell shape determining protein MreB Mrl
ACX60_03610	COG1792	Involved in formation and maintenance of cell shape
ACX60_03615	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACX60_03620	COG0424	maF-like protein
ACX60_03625	COG1530	ribonuclease E activity
ACX60_03635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_03655	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_03680	COG2207	Transcriptional regulator
ACX60_03700	COG1113	amino acid transport
ACX60_03705	COG2828	Protein conserved in bacteria
ACX60_03710	COG0142	geranyltranstransferase activity
ACX60_03715	COG2315	Protein conserved in bacteria
ACX60_03730	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACX60_03750	COG2194	sulfuric ester hydrolase activity
ACX60_03755	COG0745	RESPONSE REGULATOR receiver
ACX60_03760	COG0642	Histidine kinase
ACX60_03770	COG0004	ammonium transporteR
ACX60_03775	COG0583	DNA-binding transcription factor activity
ACX60_03795	COG0525	valine-tRNA ligase activity
ACX60_03805	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_03815	COG0393	Putative heavy-metal-binding
ACX60_03820	COG0393	Putative heavy-metal-binding
ACX60_03825	COG1538	Outer membrane efflux protein
ACX60_03835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_03840	COG0671	phosphoesterase, PA-phosphatase related
ACX60_03870	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACX60_03885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACX60_03885	COG1648	precorrin-2 dehydrogenase activity
ACX60_03890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACX60_03895	COG1733	regulation of RNA biosynthetic process
ACX60_03905	COG0531	amino acid
ACX60_03920	COG0321	lipoyl(octanoyl) transferase activity
ACX60_03925	COG2921	Belongs to the UPF0250 family
ACX60_03965	COG2009	succinate dehydrogenase
ACX60_03970	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACX60_03975	COG1053	succinate dehydrogenase
ACX60_03980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACX60_03995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX60_04015	COG2354	Protein conserved in bacteria
ACX60_04020	COG2321	neutral zinc metallopeptidase
ACX60_04040	COG2843	Capsule synthesis protein
ACX60_04055	COG0589	response to stress
ACX60_04065	COG0251	oxidation-reduction process
ACX60_04070	COG1309	transcriptional regulator
ACX60_04085	COG0505	Belongs to the CarA family
ACX60_04110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACX60_04115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACX60_04165	COG0477	Major facilitator Superfamily
ACX60_04170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACX60_04190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACX60_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_04215	COG0584	glycerophosphoryl diester phosphodiesterase
ACX60_04235	COG0741	lytic transglycosylase activity
ACX60_04255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACX60_04270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_04280	COG3811	Belongs to the UPF0386 family
ACX60_04335	COG0778	Nitroreductase
ACX60_04350	COG1929	Belongs to the glycerate kinase type-1 family
ACX60_04355	COG0243	molybdopterin cofactor binding
ACX60_04360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACX60_04365	COG3339	Conserved Protein
ACX60_04375	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACX60_04390	COG1113	amino acid transport
ACX60_04400	COG0019	diaminopimelate decarboxylase activity
ACX60_04410	COG1280	lysine exporter protein (LysE YggA)
ACX60_04415	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACX60_04445	COG0463	Glycosyl transferase, family 2
ACX60_04465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_04495	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACX60_04500	COG1136	(ABC) transporter
ACX60_04505	COG0658	competence protein
ACX60_04505	COG2333	competence protein COMEC
ACX60_04515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACX60_04515	COG0616	signal peptide processing
ACX60_04520	COG0596	Alpha beta hydrolase
ACX60_04525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACX60_04535	COG0628	permease
ACX60_04570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACX60_04590	COG0823	Involved in the tonB-independent uptake of proteins
ACX60_04610	COG0824	Thioesterase
ACX60_04615	COG1473	amidohydrolase
ACX60_04635	COG0047	phosphoribosylformylglycinamidine synthase activity
ACX60_04635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACX60_04660	COG1169	isochorismate synthase
ACX60_04670	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_04675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_04680	COG2226	methyltransferase
ACX60_04680	COG3433	isochorismatase activity
ACX60_04680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_04685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_04690	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACX60_04695	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ACX60_04700	COG0019	diaminopimelate decarboxylase activity
ACX60_04725	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACX60_04730	COG4774	siderophore transport
ACX60_04745	COG0534	Mate efflux family protein
ACX60_04755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_04825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACX60_04830	COG1024	Enoyl-CoA hydratase
ACX60_04835	COG1051	belongs to the nudix hydrolase family
ACX60_04835	COG1056	cytidyltransferase-related domain
ACX60_04845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACX60_04860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACX60_04875	COG4625	pathogenesis
ACX60_04880	COG0583	DNA-binding transcription factor activity
ACX60_04885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACX60_04890	COG4208	sulfate ABC transporter
ACX60_04895	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACX60_04905	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACX60_04910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACX60_04915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACX60_04935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACX60_04945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACX60_04955	COG0681	Belongs to the peptidase S26 family
ACX60_04970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACX60_04980	COG1381	Involved in DNA repair and RecF pathway recombination
ACX60_04985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACX60_04995	COG4221	oxidoreductase activity
ACX60_05020	COG0443	Heat shock 70 kDa protein
ACX60_05050	COG0556	nucleotide-excision repair
ACX60_05105	COG2070	2-Nitropropane dioxygenase
ACX60_05135	COG1215	transferase activity, transferring glycosyl groups
ACX60_05150	COG0415	Belongs to the DNA photolyase family
ACX60_05160	COG1252	NADH dehydrogenase
ACX60_05165	COG1686	Belongs to the peptidase S11 family
ACX60_05180	COG1187	pseudouridine synthase activity
ACX60_05200	COG0477	Major facilitator Superfamily
ACX60_05205	COG0583	DNA-binding transcription factor activity
ACX60_05220	COG0612	Peptidase, M16
ACX60_05245	COG0352	thiamine-phosphate diphosphorylase activity
ACX60_05280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_05290	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_05305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACX60_05310	COG0076	glutamate decarboxylase activity
ACX60_05320	COG1522	sequence-specific DNA binding
ACX60_05325	COG3961	Belongs to the TPP enzyme family
ACX60_05330	COG1113	amino acid transport
ACX60_05335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACX60_05340	COG0573	inorganic phosphate transmembrane transporter activity
ACX60_05350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACX60_05355	COG0616	signal peptide processing
ACX60_05390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACX60_05395	COG1686	Belongs to the peptidase S11 family
ACX60_05420	COG0583	DNA-binding transcription factor activity
ACX60_05425	COG1067	ATP-dependent peptidase activity
ACX60_05450	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACX60_05470	COG1966	Carbon starvation protein
ACX60_05475	COG2879	small protein
ACX60_05515	COG1335	isochorismatase
ACX60_05520	COG0583	DNA-binding transcription factor activity
ACX60_05535	COG0596	Alpha beta hydrolase
ACX60_05545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACX60_05575	COG1741	Belongs to the pirin family
ACX60_05585	COG2964	Protein conserved in bacteria
ACX60_05600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_05605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACX60_05610	COG4605	iron ion homeostasis
ACX60_05615	COG4604	ABC transporter, ATP-binding protein
ACX60_05620	COG4607	ABC-type enterochelin transport system periplasmic component
ACX60_05625	COG4774	siderophore transport
ACX60_05635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_05640	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACX60_05645	COG1535	isochorismatase
ACX60_05645	COG3433	isochorismatase activity
ACX60_05660	COG1132	(ABC) transporter
ACX60_05670	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACX60_05695	COG3739	integral membrane protein
ACX60_05725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACX60_05755	COG0308	aminopeptidase N
ACX60_05760	COG0512	Glutamine amidotransferase of anthranilate synthase
ACX60_05770	COG3104	oligopeptide transport
ACX60_05785	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACX60_05820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACX60_05825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACX60_05830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACX60_05850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACX60_05855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACX60_05860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACX60_05875	COG1960	acyl-CoA dehydrogenase activity
ACX60_05880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACX60_05885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX60_05900	COG2223	nitrite transmembrane transporter activity
ACX60_05910	COG0024	Methionine aminopeptidase
ACX60_05915	COG0052	Belongs to the universal ribosomal protein uS2 family
ACX60_05930	COG2207	Transcriptional regulator
ACX60_05955	COG2951	lytic endotransglycosylase activity
ACX60_05960	COG0772	Belongs to the SEDS family
ACX60_05975	COG0842	Transport permease protein
ACX60_05980	COG1131	(ABC) transporter
ACX60_06010	COG1538	Outer membrane efflux protein
ACX60_06020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_06035	COG4215	(ABC) transporter
ACX60_06040	COG4160	amino acid transport
ACX60_06045	COG4598	ABC transporter
ACX60_06055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX60_06065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_06080	COG1720	tRNA m6t6A37 methyltransferase activity
ACX60_06100	COG0745	RESPONSE REGULATOR receiver
ACX60_06105	COG0642	Histidine kinase
ACX60_06115	COG0494	nUDIX hydrolase
ACX60_06125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACX60_06130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACX60_06135	COG3139	Protein of unknown function (DUF1315)
ACX60_06140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACX60_06145	COG1301	dicarboxylic acid transport
ACX60_06150	COG1960	acyl-CoA dehydrogenase activity
ACX60_06155	COG2819	hydrolase of the alpha beta superfamily
ACX60_06165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACX60_06175	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACX60_06195	COG1690	Belongs to the RtcB family
ACX60_06200	COG1234	tRNA 3'-trailer cleavage
ACX60_06205	COG4650	regulator
ACX60_06235	COG2363	Small membrane protein
ACX60_06255	COG0513	Belongs to the DEAD box helicase family
ACX60_06265	COG0778	Nitroreductase
ACX60_06295	COG1286	toxin biosynthetic process
ACX60_06320	COG4783	chaperone-mediated protein folding
ACX60_06325	COG1610	YqeY-like protein
ACX60_06330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACX60_06355	COG0515	serine threonine protein kinase
ACX60_06355	COG2815	serine threonine protein kinase
ACX60_06425	COG3111	PFAM Bacterial OB fold (BOF) protein
ACX60_06450	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACX60_06455	COG0786	glutamate:sodium symporter activity
ACX60_06465	COG2186	Transcriptional regulator
ACX60_06515	COG0477	Major facilitator Superfamily
ACX60_06520	COG1051	belongs to the nudix hydrolase family
ACX60_06550	COG2995	paraquat-inducible protein a
ACX60_06555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACX60_06555	COG3008	intermembrane lipid transfer
ACX60_06570	COG1794	racemase activity, acting on amino acids and derivatives
ACX60_06600	COG1301	dicarboxylic acid transport
ACX60_06610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_06615	COG2011	ABC-type metal ion transport system permease component
ACX60_06620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACX60_06625	COG1464	Belongs to the NlpA lipoprotein family
ACX60_06630	COG0151	Belongs to the GarS family
ACX60_06635	COG0138	bifunctional purine biosynthesis protein purh
ACX60_06640	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACX60_06670	COG2308	Evidence 4 Homologs of previously reported genes of
ACX60_06680	COG1305	Transglutaminase-like
ACX60_06690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACX60_06695	COG0305	Participates in initiation and elongation during chromosome replication
ACX60_06720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACX60_06730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACX60_06735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACX60_06760	COG0726	polysaccharide deacetylase
ACX60_06760	COG1649	PFAM Uncharacterised BCR, COG1649
ACX60_06765	COG1215	transferase activity, transferring glycosyl groups
ACX60_06770	COG3658	cytochrome
ACX60_06780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACX60_06795	COG0583	DNA-binding transcription factor activity
ACX60_06825	COG1960	acyl-CoA dehydrogenase activity
ACX60_06830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX60_06835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_06850	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACX60_06860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACX60_06865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACX60_06870	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACX60_06875	COG2205	protein histidine kinase activity
ACX60_06880	COG0745	RESPONSE REGULATOR receiver
ACX60_06885	COG0174	glutamine synthetase
ACX60_06905	COG0729	surface antigen
ACX60_06930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACX60_06935	COG2814	Major facilitator Superfamily
ACX60_06950	COG0583	DNA-binding transcription factor activity
ACX60_06965	COG1187	pseudouridine synthase activity
ACX60_06985	COG0802	atpase or kinase
ACX60_06990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACX60_07000	COG1923	regulation of RNA biosynthetic process
ACX60_07005	COG0697	spore germination
ACX60_07035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACX60_07035	COG0519	Catalyzes the synthesis of GMP from XMP
ACX60_07040	COG4302	ethanolamine ammonia-lyase activity
ACX60_07045	COG4303	Ethanolamine ammonia lyase large subunit
ACX60_07050	COG0531	amino acid
ACX60_07070	COG1454	alcohol dehydrogenase
ACX60_07075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACX60_07100	COG0308	aminopeptidase N
ACX60_07140	COG1605	Chorismate mutase
ACX60_07155	COG1309	transcriptional regulator
ACX60_07165	COG0668	transmembrane transport
ACX60_07195	COG4773	Receptor
ACX60_07215	COG0488	(ABC) transporter
ACX60_07220	COG0589	response to stress
ACX60_07240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACX60_07250	COG3135	benzoate transporter
ACX60_07255	COG1522	sequence-specific DNA binding
ACX60_07270	COG0583	DNA-binding transcription factor activity
ACX60_07280	COG0183	Belongs to the thiolase family
ACX60_07310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACX60_07320	COG0824	Thioesterase
ACX60_07325	COG1454	alcohol dehydrogenase
ACX60_07335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACX60_07355	COG0069	glutamate synthase activity
ACX60_07500	COG3617	BRO family, N-terminal domain
ACX60_07535	COG5410	chromosome segregation
ACX60_07640	COG1598	PFAM Uncharacterised protein family UPF0150
ACX60_07700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX60_07715	COG2814	Major facilitator Superfamily
ACX60_07730	COG0511	ligase activity, forming carbon-carbon bonds
ACX60_07745	COG1116	anion transmembrane transporter activity
ACX60_07745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX60_07750	COG0745	RESPONSE REGULATOR receiver
ACX60_07760	COG2146	nitrite reductase [NAD(P)H] activity
ACX60_07760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX60_07765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX60_07770	COG0243	molybdopterin cofactor binding
ACX60_07780	COG0243	molybdopterin cofactor binding
ACX60_07785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACX60_07800	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACX60_07800	COG0315	cyclic pyranopterin monophosphate synthase activity
ACX60_07805	COG0303	'Molybdopterin
ACX60_07815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_07820	COG0697	spore germination
ACX60_07840	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACX60_07845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACX60_07900	COG2204	response regulator
ACX60_07905	COG3852	Histidine kinase
ACX60_07925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACX60_07930	COG0575	Belongs to the CDS family
ACX60_07945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACX60_07965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX60_07975	COG2137	regulation of response to DNA damage stimulus
ACX60_07985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACX60_07990	COG1011	Hydrolase
ACX60_08015	COG1522	sequence-specific DNA binding
ACX60_08025	COG1113	amino acid transport
ACX60_08040	COG0659	secondary active sulfate transmembrane transporter activity
ACX60_08045	COG2135	peptidase activity
ACX60_08060	COG5001	Diguanylate cyclase
ACX60_08060	COG3300	MHYT domain
ACX60_08075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACX60_08075	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACX60_08075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACX60_08080	COG1105	Belongs to the carbohydrate kinase PfkB family
ACX60_08085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACX60_08085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACX60_08115	COG0024	Methionine aminopeptidase
ACX60_08120	COG0583	DNA-binding transcription factor activity
ACX60_08130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACX60_08135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACX60_08140	COG0516	GMP reductase activity
ACX60_08140	COG0517	IMP dehydrogenase activity
ACX60_08165	COG0552	protein localization to endoplasmic reticulum
ACX60_08175	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ACX60_08190	COG4890	Cyd operon protein YbgT
ACX60_08195	COG1294	oxidase, subunit
ACX60_08210	COG1585	Membrane protein implicated in regulation of membrane protease activity
ACX60_08220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACX60_08225	COG4774	siderophore transport
ACX60_08240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACX60_08245	COG0569	domain protein
ACX60_08250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACX60_08280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACX60_08285	COG0542	response to heat
ACX60_08295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACX60_08310	COG1902	pentaerythritol trinitrate reductase activity
ACX60_08310	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX60_08355	COG2323	membrane
ACX60_08360	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACX60_08370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX60_08375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX60_08380	COG0183	Belongs to the thiolase family
ACX60_08385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACX60_08390	COG0596	Alpha beta hydrolase
ACX60_08395	COG2271	Major facilitator Superfamily
ACX60_08400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACX60_08405	COG3485	protocatechuate 3,4-dioxygenase
ACX60_08410	COG3485	protocatechuate 3,4-dioxygenase
ACX60_08415	COG0710	3-dehydroquinate dehydratase activity
ACX60_08420	COG3420	alginic acid biosynthetic process
ACX60_08425	COG3659	wide pore channel activity
ACX60_08430	COG4993	Dehydrogenase
ACX60_08440	COG2391	methyltransferase activity
ACX60_08455	COG1414	Transcriptional regulator
ACX60_08460	COG0583	DNA-binding transcription factor activity
ACX60_08465	COG1960	acyl-CoA dehydrogenase activity
ACX60_08490	COG2814	Major facilitator Superfamily
ACX60_08500	COG0154	amidase activity
ACX60_08520	COG4638	Rieske (2fe-2S)
ACX60_08530	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_08540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_08550	COG3733	amine oxidase
ACX60_08560	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_08570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX60_08575	COG0183	Belongs to the thiolase family
ACX60_08580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX60_08585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX60_08595	COG4829	muconolactone delta-isomerase
ACX60_08600	COG4948	Mandelate Racemase Muconate Lactonizing
ACX60_08605	COG0583	DNA-binding transcription factor activity
ACX60_08615	COG2186	Transcriptional regulator
ACX60_08635	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_08650	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX60_08650	COG1902	pentaerythritol trinitrate reductase activity
ACX60_08660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACX60_08670	COG0789	Transcriptional regulator
ACX60_08695	COG1309	transcriptional regulator
ACX60_08700	COG0583	DNA-binding transcription factor activity
ACX60_08705	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_08710	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_08715	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_08725	COG1960	acyl-CoA dehydrogenase activity
ACX60_08735	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_08835	COG0583	DNA-binding transcription factor activity
ACX60_08850	COG1566	PFAM secretion protein HlyD family protein
ACX60_08865	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_08870	COG0129	dihydroxy-acid dehydratase activity
ACX60_08880	COG0583	DNA-binding transcription factor activity
ACX60_08885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACX60_08895	COG2084	Dehydrogenase
ACX60_08900	COG2207	Transcriptional regulator
ACX60_08905	COG1064	alcohol dehydrogenase
ACX60_08920	COG1120	ATPase activity
ACX60_09015	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACX60_09050	COG2856	Zn peptidase
ACX60_09100	COG2207	Transcriptional regulator
ACX60_09115	COG2205	protein histidine kinase activity
ACX60_09120	COG0745	RESPONSE REGULATOR receiver
ACX60_09125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_09130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACX60_09165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_09175	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_09180	COG0412	Dienelactone hydrolase
ACX60_09190	COG2207	Transcriptional regulator
ACX60_09195	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_09200	COG2610	gluconate transmembrane transporter activity
ACX60_09210	COG1309	transcriptional regulator
ACX60_09230	COG0583	DNA-binding transcription factor activity
ACX60_09245	COG2031	fatty acid transporter
ACX60_09250	COG0183	Belongs to the thiolase family
ACX60_09255	COG0583	DNA-binding transcription factor activity
ACX60_09260	COG0583	DNA-binding transcription factor activity
ACX60_09275	COG1027	Aspartate ammonia-lyase
ACX60_09285	COG0477	Major facilitator Superfamily
ACX60_09305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX60_09310	COG4521	taurine ABC transporter
ACX60_09335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACX60_09340	COG1733	regulation of RNA biosynthetic process
ACX60_09345	COG3708	Transcriptional regulator
ACX60_09345	COG2207	Transcriptional regulator
ACX60_09360	COG0730	response to heat
ACX60_09370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_09370	COG3453	Protein conserved in bacteria
ACX60_09380	COG3781	membrane
ACX60_09385	COG1063	alcohol dehydrogenase
ACX60_09395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX60_09400	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACX60_09405	COG0022	dehydrogenase e1 component
ACX60_09410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACX60_09415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACX60_09430	COG3706	GGDEF domain
ACX60_09445	COG0133	tryptophan synthase activity
ACX60_09455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACX60_09485	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ACX60_09490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACX60_09515	COG2226	methyltransferase
ACX60_09570	COG0842	Transport permease protein
ACX60_09575	COG0842	Transport permease protein
ACX60_09580	COG1131	(ABC) transporter
ACX60_09595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX60_09600	COG4773	Receptor
ACX60_09620	COG0730	response to heat
ACX60_09625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACX60_09640	COG0406	alpha-ribazole phosphatase activity
ACX60_09645	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACX60_09660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACX60_09690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACX60_09700	COG4264	IucA IucC family
ACX60_09705	COG4264	IucA IucC family
ACX60_09710	COG2814	Major facilitator Superfamily
ACX60_09725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACX60_09740	COG1960	acyl-CoA dehydrogenase activity
ACX60_09745	COG1960	acyl-CoA dehydrogenase activity
ACX60_09750	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACX60_09755	COG2207	Transcriptional regulator
ACX60_09765	COG0776	regulation of translation
ACX60_09790	COG0822	iron-sulfur transferase activity
ACX60_09795	COG0316	Belongs to the HesB IscA family
ACX60_09825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACX60_09845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACX60_09850	COG0702	epimerase
ACX60_09885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACX60_09895	COG0339	signal peptide processing
ACX60_09940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACX60_10050	COG4695	Portal protein
ACX60_10130	COG0305	Participates in initiation and elongation during chromosome replication
ACX60_10205	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACX60_10235	COG0776	regulation of translation
ACX60_10255	COG0590	tRNA wobble adenosine to inosine editing
ACX60_10300	COG0084	hydrolase, TatD family'
ACX60_10320	COG1663	tetraacyldisaccharide 4'-kinase activity
ACX60_10325	COG1132	(ABC) transporter
ACX60_10335	COG0811	peptide transport
ACX60_10340	COG1475	DNA binding
ACX60_10345	COG1192	Involved in chromosome partitioning
ACX60_10355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACX60_10370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACX60_10375	COG0191	fructose-bisphosphate aldolase activity
ACX60_10395	COG0424	maF-like protein
ACX60_10400	COG2850	peptidyl-arginine hydroxylation
ACX60_10410	COG0640	Transcriptional regulator
ACX60_10420	COG3619	membrane
ACX60_10425	COG3122	Protein conserved in bacteria
ACX60_10430	COG1132	(ABC) transporter
ACX60_10450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACX60_10455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACX60_10465	COG0506	proline dehydrogenase activity
ACX60_10465	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACX60_10465	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACX60_10470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACX60_10485	COG3698	Phosphodiester glycosidase
ACX60_10495	COG2353	YceI-like domain
ACX60_10505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACX60_10550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACX60_10550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACX60_10575	COG3539	Fimbrial protein
ACX60_10580	COG3121	Chaperone
ACX60_10605	COG0697	spore germination
ACX60_10615	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACX60_10625	COG0583	DNA-binding transcription factor activity
ACX60_10645	COG1309	transcriptional regulator
ACX60_10660	COG1522	sequence-specific DNA binding
ACX60_10670	COG1126	abc transporter atp-binding protein
ACX60_10675	COG0765	amino acid transport
ACX60_10680	COG0765	amino acid transport
ACX60_10710	COG1464	Belongs to the NlpA lipoprotein family
ACX60_10720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACX60_10725	COG2011	ABC-type metal ion transport system permease component
ACX60_10730	COG0012	GTP binding
ACX60_10755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACX60_10795	COG0386	Belongs to the glutathione peroxidase family
ACX60_10805	COG0436	Aminotransferase
ACX60_10810	COG1301	dicarboxylic acid transport
ACX60_10845	COG3634	alkyl hydroperoxide reductase activity
ACX60_10860	COG0583	DNA-binding transcription factor activity
ACX60_10865	COG0798	PFAM Bile acid sodium symporter
ACX60_10870	COG0640	Transcriptional regulator
ACX60_10885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACX60_10895	COG0583	DNA-binding transcription factor activity
ACX60_10905	COG1953	Uracil, thiamine, allantoin
ACX60_10915	COG2175	clavaminate synthase activity
ACX60_10920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX60_10925	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACX60_10930	COG4521	taurine ABC transporter
ACX60_10940	COG0477	Major facilitator Superfamily
ACX60_10960	COG1271	oxidase subunit
ACX60_10965	COG1294	oxidase, subunit
ACX60_10975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_10995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACX60_11015	COG3052	prosthetic group binding
ACX60_11020	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ACX60_11030	COG0583	DNA-binding transcription factor activity
ACX60_11040	COG2814	Major facilitator Superfamily
ACX60_11055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_11060	COG1346	cytolysis
ACX60_11070	COG0583	DNA-binding transcription factor activity
ACX60_11075	COG0625	glutathione transferase activity
ACX60_11080	COG0625	glutathione transferase activity
ACX60_11085	COG0583	DNA-binding transcription factor activity
ACX60_11100	COG1045	serine acetyltransferase
ACX60_11105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACX60_11110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACX60_11125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX60_11130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX60_11140	COG0765	amino acid transport
ACX60_11145	COG0765	amino acid transport
ACX60_11160	COG0784	Response regulator, receiver
ACX60_11160	COG2205	protein histidine kinase activity
ACX60_11200	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_11250	COG0583	DNA-binding transcription factor activity
ACX60_11270	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_11275	COG1309	transcriptional regulator
ACX60_11280	COG1960	acyl-CoA dehydrogenase activity
ACX60_11285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACX60_11290	COG1024	Enoyl-CoA hydratase
ACX60_11305	COG0583	DNA-binding transcription factor activity
ACX60_11320	COG1280	lysine exporter protein (LysE YggA)
ACX60_11325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACX60_11330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACX60_11345	COG3842	ATPase activity
ACX60_11350	COG1840	ABC-type Fe3 transport system, periplasmic component
ACX60_11365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX60_11370	COG1414	Transcriptional regulator
ACX60_11380	COG0583	DNA-binding transcription factor activity
ACX60_11385	COG3038	cytochrome b561
ACX60_11390	COG0753	catalase activity
ACX60_11420	COG2050	protein possibly involved in aromatic compounds catabolism
ACX60_11430	COG3327	negative regulation of DNA-templated transcription, initiation
ACX60_11435	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ACX60_11440	COG0183	Belongs to the thiolase family
ACX60_11445	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX60_11450	COG1024	Enoyl-CoA hydratase
ACX60_11455	COG1024	Enoyl-CoA hydratase
ACX60_11460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_11465	COG2151	metal-sulfur cluster biosynthetic enzyme
ACX60_11470	COG3396	Phenylacetate-CoA oxygenase
ACX60_11475	COG3460	Phenylacetate-CoA oxygenase
ACX60_11480	COG3396	Phenylacetate-CoA oxygenase
ACX60_11485	COG2030	dehydratase
ACX60_11485	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_11490	COG1760	l-serine dehydratase
ACX60_11495	COG0531	amino acid
ACX60_11500	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_11525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACX60_11545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX60_11555	COG0789	Transcriptional regulator
ACX60_11565	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACX60_11580	COG2807	transmembrane transport
ACX60_11585	COG0590	tRNA wobble adenosine to inosine editing
ACX60_11595	COG0583	DNA-binding transcription factor activity
ACX60_11635	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACX60_11635	COG2885	chlorophyll binding
ACX60_11690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACX60_11715	COG1116	anion transmembrane transporter activity
ACX60_11720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX60_11730	COG0864	Transcriptional regulator
ACX60_11745	COG1733	regulation of RNA biosynthetic process
ACX60_11750	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_11755	COG0439	Biotin carboxylase
ACX60_11770	COG1063	alcohol dehydrogenase
ACX60_11780	COG1309	transcriptional regulator
ACX60_11790	COG0038	chloride channel
ACX60_11795	COG4770	biotin carboxylase activity
ACX60_11815	COG1914	H( )-stimulated, divalent metal cation uptake system
ACX60_11820	COG0583	DNA-binding transcription factor activity
ACX60_11850	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX60_11870	COG2814	Major facilitator Superfamily
ACX60_11885	COG0598	Magnesium transport protein CorA
ACX60_11890	COG1560	Kdo2-lipid A biosynthetic process
ACX60_11900	COG5006	permease, DMT superfamily
ACX60_11905	COG1522	sequence-specific DNA binding
ACX60_11920	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACX60_11960	COG1538	Outer membrane efflux protein
ACX60_11965	COG1137	ATPase activity
ACX60_11970	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACX60_11980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACX60_11985	COG0517	IMP dehydrogenase activity
ACX60_11985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACX60_12020	COG1733	regulation of RNA biosynthetic process
ACX60_12025	COG2814	Major facilitator Superfamily
ACX60_12055	COG1278	Cold shock
ACX60_12060	COG1280	lysine exporter protein (LysE YggA)
ACX60_12095	COG1570	exodeoxyribonuclease VII activity
ACX60_12150	COG0583	DNA-binding transcription factor activity
ACX60_12155	COG4638	Rieske (2fe-2S)
ACX60_12160	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACX60_12165	COG0633	Ferredoxin
ACX60_12165	COG0543	2 iron, 2 sulfur cluster binding
ACX60_12170	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_12175	COG3135	benzoate transporter
ACX60_12180	COG2814	Major facilitator Superfamily
ACX60_12195	COG1643	Atp-dependent helicase
ACX60_12200	COG0450	alkyl hydroperoxide reductase
ACX60_12210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACX60_12220	COG3634	alkyl hydroperoxide reductase activity
ACX60_12240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACX60_12245	COG0625	glutathione transferase activity
ACX60_12255	COG2885	chlorophyll binding
ACX60_12305	COG1765	OsmC-like protein
ACX60_12315	COG0667	Aldo Keto reductase
ACX60_12330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACX60_12350	COG0582	viral genome integration into host DNA
ACX60_12485	COG3566	protein conserved in bacteria
ACX60_12510	COG3567	Phage-associated protein, HI1409 family
ACX60_12515	COG5410	chromosome segregation
ACX60_12595	COG4197	protein conserved in bacteria, prophage-related
ACX60_12600	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACX60_12660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACX60_12670	COG3038	cytochrome b561
ACX60_12675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACX60_12680	COG2252	PERMEase
ACX60_12690	COG2072	flavoprotein involved in K transport
ACX60_12705	COG1741	Belongs to the pirin family
ACX60_12710	COG1309	transcriptional regulator
ACX60_12720	COG0300	oxidoreductase activity
ACX60_12725	COG2072	flavoprotein involved in K transport
ACX60_12730	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACX60_12775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_12790	COG2814	Major facilitator Superfamily
ACX60_12795	COG1024	Enoyl-CoA hydratase
ACX60_12800	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_12810	COG1960	acyl-CoA dehydrogenase activity
ACX60_12835	COG2186	Transcriptional regulator
ACX60_12840	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_12850	COG4948	Mandelate Racemase Muconate Lactonizing
ACX60_12855	COG2271	Major facilitator Superfamily
ACX60_12860	COG2721	sulfolactate sulfo-lyase activity
ACX60_12865	COG0697	spore germination
ACX60_12895	COG1113	amino acid transport
ACX60_12915	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_12935	COG0531	amino acid
ACX60_12945	COG1113	amino acid transport
ACX60_12990	COG0583	DNA-binding transcription factor activity
ACX60_13000	COG0251	oxidation-reduction process
ACX60_13040	COG1902	pentaerythritol trinitrate reductase activity
ACX60_13040	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX60_13055	COG2203	Gaf domain
ACX60_13055	COG3706	GGDEF domain
ACX60_13055	COG4251	negative regulation of phosphorylation
ACX60_13055	COG5001	Diguanylate cyclase
ACX60_13065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX60_13085	COG4172	Belongs to the ABC transporter superfamily
ACX60_13090	COG4239	(ABC) transporter, permease
ACX60_13095	COG4174	ABC transporter (Permease)
ACX60_13105	COG0741	lytic transglycosylase activity
ACX60_13105	COG1388	LysM domain
ACX60_13105	COG0741	lytic transglycosylase activity
ACX60_13105	COG1388	LysM domain
ACX60_13110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX60_13150	COG0583	DNA-binding transcription factor activity
ACX60_13155	COG1279	arginine transmembrane transporter activity
ACX60_13175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX60_13180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX60_13185	COG0006	proline dipeptidase activity
ACX60_13215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACX60_13240	COG3384	dioxygenase
ACX60_13250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACX60_13255	COG2878	Part of a membrane complex involved in electron transport
ACX60_13260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACX60_13280	COG0768	penicillin binding
ACX60_13285	COG0742	ribosomal rna small subunit methyltransferase
ACX60_13300	COG0830	nickel cation binding
ACX60_13310	COG0804	urea catabolic process
ACX60_13355	COG1253	flavin adenine dinucleotide binding
ACX60_13360	COG2851	Citrate transporter
ACX60_13405	COG1773	rubredoxin
ACX60_13410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX60_13420	COG0583	DNA-binding transcription factor activity
ACX60_13445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACX60_13450	COG4181	ATPase activity
ACX60_13495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACX60_13515	COG0306	phosphate transporter
ACX60_13525	COG3958	Transketolase
ACX60_13530	COG3959	Transketolase, thiamine diphosphate binding domain
ACX60_13535	COG2271	Major facilitator Superfamily
ACX60_13540	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_13545	COG0583	DNA-binding transcription factor activity
ACX60_13565	COG2223	nitrite transmembrane transporter activity
ACX60_13570	COG2207	Transcriptional regulator
ACX60_13575	COG2066	Belongs to the glutaminase family
ACX60_13580	COG0242	peptide deformylase activity
ACX60_13585	COG0477	Major facilitator Superfamily
ACX60_13595	COG0028	Belongs to the TPP enzyme family
ACX60_13610	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_13615	COG2267	carboxylic ester hydrolase activity
ACX60_13625	COG2271	Major facilitator Superfamily
ACX60_13630	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX60_13640	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_13660	COG1414	Transcriptional regulator
ACX60_13675	COG1024	Enoyl-CoA hydratase
ACX60_13685	COG1215	transferase activity, transferring glycosyl groups
ACX60_13690	COG0726	polysaccharide deacetylase
ACX60_13690	COG1649	PFAM Uncharacterised BCR, COG1649
ACX60_13700	COG4681	YaeQ
ACX60_13710	COG0523	cobalamin synthesis protein
ACX60_13720	COG1607	acyl-coa hydrolase
ACX60_13730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX60_13735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX60_13740	COG1309	transcriptional regulator
ACX60_13765	COG2040	homocysteine
ACX60_13770	COG0531	amino acid
ACX60_13795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX60_13800	COG0477	Major facilitator Superfamily
ACX60_13835	COG0405	Gamma-glutamyltransferase
ACX60_13840	COG2814	Major facilitator Superfamily
ACX60_13850	COG2050	protein possibly involved in aromatic compounds catabolism
ACX60_13865	COG1090	epimerase
ACX60_13885	COG0420	3'-5' exonuclease activity
ACX60_13910	COG0735	belongs to the Fur family
ACX60_13915	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACX60_13935	COG0121	glutamine amidotransferase
ACX60_13950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX60_13960	COG0210	DNA helicase
ACX60_13965	COG2885	chlorophyll binding
ACX60_13970	COG0204	Acyl-transferase
ACX60_13985	COG2894	cell division
ACX60_14000	COG1280	lysine exporter protein (LysE YggA)
ACX60_14005	COG1674	ftsk spoiiie
ACX60_14005	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACX60_14010	COG0492	ferredoxin-NADP+ reductase activity
ACX60_14015	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACX60_14025	COG0456	acetyltransferase
ACX60_14085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACX60_14085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACX60_14105	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_14125	COG0473	3-isopropylmalate dehydrogenase activity
ACX60_14130	COG0583	DNA-binding transcription factor activity
ACX60_14145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX60_14170	COG0564	pseudouridine synthase activity
ACX60_14180	COG0358	DNA primase activity
ACX60_14195	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACX60_14225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACX60_14255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACX60_14265	COG0351	phosphomethylpyrimidine kinase
ACX60_14265	COG0352	thiamine-phosphate diphosphorylase activity
ACX60_14265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACX60_14270	COG1652	LysM domain
ACX60_14295	COG1399	metal-binding, possibly nucleic acid-binding protein
ACX60_14300	COG3101	peptidyl-lysine hydroxylation
ACX60_14305	COG0009	L-threonylcarbamoyladenylate synthase
ACX60_14310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACX60_14315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACX60_14330	COG4106	trans-aconitate 2-methyltransferase activity
ACX60_14345	COG0596	Alpha beta hydrolase
ACX60_14345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX60_14345	COG2226	methyltransferase
ACX60_14350	COG1877	trehalose-phosphatase activity
ACX60_14355	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACX60_14360	COG2223	nitrite transmembrane transporter activity
ACX60_14380	COG1196	nuclear chromosome segregation
ACX60_14390	COG0730	response to heat
ACX60_14405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACX60_14415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACX60_14465	COG0489	protein tyrosine kinase activity
ACX60_14475	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX60_14475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX60_14505	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ACX60_14510	COG2081	HI0933 family
ACX60_14520	COG0668	transmembrane transport
ACX60_14540	COG0583	DNA-binding transcription factor activity
ACX60_14565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACX60_14570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACX60_14600	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACX60_14635	COG2205	protein histidine kinase activity
ACX60_14640	COG0745	RESPONSE REGULATOR receiver
ACX60_14655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACX60_14700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_14705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACX60_14715	COG0583	DNA-binding transcription factor activity
ACX60_14735	COG1473	amidohydrolase
ACX60_14745	COG0583	DNA-binding transcription factor activity
ACX60_14760	COG0583	DNA-binding transcription factor activity
ACX60_14765	COG1053	succinate dehydrogenase
ACX60_14775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACX60_14780	COG2814	Major facilitator Superfamily
ACX60_14785	COG1960	acyl-CoA dehydrogenase activity
ACX60_14790	COG0583	DNA-binding transcription factor activity
ACX60_14795	COG1063	alcohol dehydrogenase
ACX60_14825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACX60_14830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACX60_14835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACX60_14855	COG2132	Multicopper oxidase
ACX60_14865	COG0561	phosphatase activity
ACX60_14870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACX60_14895	COG1214	PFAM Peptidase M22, glycoprotease
ACX60_14945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACX60_14955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACX60_14960	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACX60_14965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACX60_15025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACX60_15035	COG1846	Transcriptional regulator
ACX60_15040	COG1764	response to oxidative stress
ACX60_15080	COG0037	tRNA processing
ACX60_15090	COG0248	Ppx GppA phosphatase
ACX60_15115	COG0072	phenylalanine-tRNA ligase activity
ACX60_15140	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACX60_15155	COG1238	metal cluster binding
ACX60_15160	COG0625	glutathione transferase activity
ACX60_15175	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_15180	COG3028	Belongs to the UPF0307 family
ACX60_15185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACX60_15205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACX60_15210	COG0617	tRNA 3'-terminal CCA addition
ACX60_15215	COG1555	photosystem II stabilization
ACX60_15220	COG3956	TIGRFAM MazG family protein
ACX60_15230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACX60_15250	COG5002	protein histidine kinase activity
ACX60_15250	COG0784	Response regulator, receiver
ACX60_15250	COG2205	protein histidine kinase activity
ACX60_15255	COG1024	Enoyl-CoA hydratase
ACX60_15260	COG2084	Dehydrogenase
ACX60_15265	COG3622	Belongs to the hyi family
ACX60_15280	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACX60_15285	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACX60_15290	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACX60_15295	COG0697	spore germination
ACX60_15305	COG2814	Major facilitator Superfamily
ACX60_15310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACX60_15320	COG0583	DNA-binding transcription factor activity
ACX60_15325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACX60_15335	COG0084	hydrolase, TatD family'
ACX60_15350	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACX60_15370	COG3501	Rhs element vgr protein
ACX60_15400	COG0440	acetolactate synthase activity
ACX60_15405	COG0028	Belongs to the TPP enzyme family
ACX60_15430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_15435	COG1136	(ABC) transporter
ACX60_15435	COG0577	efflux transmembrane transporter activity
ACX60_15440	COG1538	Outer membrane efflux protein
ACX60_15455	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACX60_15460	COG1162	GTPase activity
ACX60_15470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACX60_15490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACX60_15495	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_15535	COG2986	histidine ammonia-lyase
ACX60_15545	COG1216	Glycosyl transferase, family 2
ACX60_15550	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_15560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACX60_15565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACX60_15605	COG1426	Protein conserved in bacteria
ACX60_15640	COG0793	Belongs to the peptidase S41A family
ACX60_15655	COG2267	carboxylic ester hydrolase activity
ACX60_15665	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_15670	COG3265	gluconokinase activity
ACX60_15680	COG0800	Aldolase
ACX60_15690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACX60_15695	COG0280	phosphate acetyltransferase
ACX60_15695	COG0857	belongs to the CobB CobQ family
ACX60_15700	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACX60_15700	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACX60_15720	COG0740	serine-type endopeptidase activity
ACX60_15730	COG4774	siderophore transport
ACX60_15740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACX60_15750	COG2813	Specifically methylates the guanine in position
ACX60_15750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX60_15850	COG0788	formyltetrahydrofolate deformylase activity
ACX60_15865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACX60_15870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACX60_15875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACX60_15875	COG4651	solute:proton antiporter activity
ACX60_15895	COG0724	RNA recognition motif
ACX60_15900	COG0210	DNA helicase
ACX60_15925	COG1733	regulation of RNA biosynthetic process
ACX60_15945	COG1280	lysine exporter protein (LysE YggA)
ACX60_15950	COG1560	Kdo2-lipid A biosynthetic process
ACX60_15960	COG1301	dicarboxylic acid transport
ACX60_16015	COG0473	3-isopropylmalate dehydrogenase activity
ACX60_16070	COG0583	DNA-binding transcription factor activity
ACX60_16080	COG0625	glutathione transferase activity
ACX60_16085	COG2378	regulation of single-species biofilm formation
ACX60_16090	COG0546	phosphoglycolate phosphatase activity
ACX60_16100	COG1530	ribonuclease E activity
ACX60_16120	COG0583	DNA-binding transcription factor activity
ACX60_16125	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_16130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACX60_16140	COG0534	Mate efflux family protein
ACX60_16155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACX60_16190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACX60_16195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_16210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACX60_16220	COG0644	oxidoreductase
ACX60_16220	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACX60_16230	COG0425	Belongs to the sulfur carrier protein TusA family
ACX60_16235	COG4535	Mg2 and Co2 transporter CorC
ACX60_16245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX60_16265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACX60_16270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACX60_16270	COG0475	glutathione-regulated potassium exporter activity
ACX60_16285	COG0484	heat shock protein binding
ACX60_16290	COG0789	Transcriptional regulator
ACX60_16295	COG0598	Magnesium transport protein CorA
ACX60_16315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACX60_16320	COG1074	ATP-dependent DNA helicase activity
ACX60_16325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACX60_16345	COG2226	methyltransferase
ACX60_16365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACX60_16380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACX60_16380	COG2111	Na H antiporter
ACX60_16385	COG1006	Multisubunit Na H antiporter MnhC subunit
ACX60_16390	COG0651	ATP synthesis coupled electron transport
ACX60_16400	COG2212	antiporter activity
ACX60_16420	COG0195	Participates in both transcription termination and antitermination
ACX60_16465	COG0237	dephospho-CoA kinase activity
ACX60_16475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACX60_16490	COG0497	DNA recombination
ACX60_16500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACX60_16530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACX60_16530	COG2169	Transcriptional regulator
ACX60_16535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACX60_16600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACX60_16615	COG0326	Molecular chaperone. Has ATPase activity
ACX60_16630	COG2056	Na+-H+ antiporter family
ACX60_16635	COG0596	Alpha beta hydrolase
ACX60_16730	COG0546	phosphoglycolate phosphatase activity
ACX60_16735	COG1716	ATPase activity
ACX60_16780	COG0181	hydroxymethylbilane synthase activity
ACX60_16790	COG3275	phosphorelay sensor kinase activity
ACX60_16810	COG1538	Outer membrane efflux protein
ACX60_16815	COG0697	spore germination
ACX60_16840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACX60_16845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACX60_16850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACX60_16855	COG0772	Belongs to the SEDS family
ACX60_16880	COG4974	Belongs to the 'phage' integrase family
ACX60_16885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX60_16895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACX60_16905	COG2197	response regulator
ACX60_16920	COG0793	Belongs to the peptidase S41A family
ACX60_16925	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACX60_16930	COG0795	lipopolysaccharide-transporting ATPase activity
ACX60_16970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACX60_16970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACX60_16980	COG0004	ammonium transporteR
ACX60_16985	COG0347	Belongs to the P(II) protein family
ACX60_17005	COG0659	secondary active sulfate transmembrane transporter activity
ACX60_17010	COG0589	response to stress
ACX60_17060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_17070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX60_17085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACX60_17100	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_17110	COG0477	Major facilitator Superfamily
ACX60_17115	COG2860	membrane
ACX60_17120	COG3012	SEC-C Motif Domain Protein
ACX60_17125	COG1253	flavin adenine dinucleotide binding
ACX60_17135	COG2814	Major facilitator Superfamily
ACX60_17145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX60_17180	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACX60_17190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACX60_17225	COG1309	transcriptional regulator
ACX60_17260	COG0758	DNA mediated transformation
ACX60_17270	COG0697	spore germination
ACX60_17275	COG1309	transcriptional regulator
ACX60_17290	COG0386	Belongs to the glutathione peroxidase family
ACX60_17360	COG1121	(ABC) transporter
ACX60_17365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACX60_17370	COG1280	lysine exporter protein (LysE YggA)
ACX60_17375	COG2837	iron assimilation
ACX60_17380	COG0281	malic enzyme
ACX60_17425	COG0519	Catalyzes the synthesis of GMP from XMP
ACX60_17425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACX60_17430	COG4399	Belongs to the UPF0754 family
ACX60_17435	COG2259	Doxx family
ACX60_17440	COG0586	Pfam SNARE associated Golgi protein
ACX60_17455	COG1192	Involved in chromosome partitioning
ACX60_17465	COG0271	Belongs to the BolA IbaG family
ACX60_17505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACX60_17505	COG3321	synthase
ACX60_17505	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ACX60_17505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACX60_17510	COG1960	acyl-CoA dehydrogenase activity
ACX60_17515	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_17520	COG2197	response regulator
ACX60_17530	COG3916	Acyl-homoserine-lactone synthase
ACX60_17535	COG0477	Major facilitator Superfamily
ACX60_17540	COG1024	Enoyl-CoA hydratase
ACX60_17545	COG1024	Enoyl-CoA hydratase
ACX60_17550	COG1960	acyl-CoA dehydrogenase activity
ACX60_17555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX60_17575	COG1113	amino acid transport
ACX60_17580	COG1113	amino acid transport
ACX60_17585	COG0251	oxidation-reduction process
ACX60_17600	COG1522	sequence-specific DNA binding
ACX60_17625	COG0564	pseudouridine synthase activity
ACX60_17695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACX60_17710	COG1802	Transcriptional regulator
ACX60_17715	COG1448	Aminotransferase
ACX60_17720	COG0277	FAD linked oxidase domain protein
ACX60_17730	COG2186	Transcriptional regulator
ACX60_17740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX60_17745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACX60_17760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACX60_17765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACX60_17790	COG0438	transferase activity, transferring glycosyl groups
ACX60_17820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACX60_17850	COG0728	peptidoglycan biosynthetic process
ACX60_17855	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACX60_17910	COG0546	phosphoglycolate phosphatase activity
ACX60_17915	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_17935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX60_17940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX60_17945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACX60_17950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX60_17955	COG1116	anion transmembrane transporter activity
ACX60_17960	COG1309	transcriptional regulator
ACX60_17965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACX60_17975	COG0196	riboflavin kinase activity
ACX60_17980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACX60_17990	COG1047	Peptidyl-prolyl cis-trans
ACX60_18030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACX60_18055	COG0583	DNA-binding transcription factor activity
ACX60_18085	COG2951	lytic endotransglycosylase activity
ACX60_18090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACX60_18105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACX60_18115	COG0671	phosphoesterase, PA-phosphatase related
ACX60_18120	COG0861	Integral membrane protein TerC family
ACX60_18130	COG0754	glutathionylspermidine amidase activity
ACX60_18140	COG0402	S-adenosylhomocysteine deaminase activity
ACX60_18160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX60_18165	COG1230	cation diffusion facilitator family transporter
ACX60_18180	COG0706	membrane insertase activity
ACX60_18195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACX60_18265	COG0739	heme binding
ACX60_18295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX60_18310	COG1192	Involved in chromosome partitioning
ACX60_18360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACX60_18495	COG1525	nuclease
ACX60_18575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACX60_18605	COG0640	Transcriptional regulator
ACX60_18660	COG4691	Plasmid stability protein
ACX60_18695	COG0798	PFAM Bile acid sodium symporter
ACX60_18730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX60_18780	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACX60_18810	COG0659	secondary active sulfate transmembrane transporter activity
ACX60_18815	COG0589	response to stress
ACX60_18870	COG0501	Belongs to the peptidase M48B family