locus-tag	class	description
H0N28_00010	COG0592	DNA-directed DNA polymerase activity
H0N28_00020	COG0187	DNA topoisomerase II activity
H0N28_00030	COG0586	Pfam SNARE associated Golgi protein
H0N28_00035	COG0488	(ABC) transporter
H0N28_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H0N28_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H0N28_00110	COG0733	neurotransmitter:sodium symporter activity
H0N28_00150	COG2233	PERMEase
H0N28_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N28_00200	COG2814	Major facilitator Superfamily
H0N28_00205	COG0656	L-ascorbic acid biosynthetic process
H0N28_00210	COG0583	DNA-binding transcription factor activity
H0N28_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N28_00230	COG1064	alcohol dehydrogenase
H0N28_00235	COG2818	Glycosylase
H0N28_00250	COG1194	a g-specific adenine glycosylase
H0N28_00270	COG2983	Belongs to the UPF0260 family
H0N28_00275	COG2133	pyrroloquinoline quinone binding
H0N28_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H0N28_00285	COG2116	formate transmembrane transporter activity
H0N28_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0N28_00310	COG1335	isochorismatase
H0N28_00315	COG0385	Bile acid
H0N28_00320	COG0534	Mate efflux family protein
H0N28_00325	COG1683	Conserved Protein
H0N28_00345	COG0625	glutathione transferase activity
H0N28_00355	COG1113	amino acid transport
H0N28_00365	COG0523	cobalamin synthesis protein
H0N28_00375	COG2188	Transcriptional regulator
H0N28_00405	COG0010	Belongs to the arginase family
H0N28_00425	COG1280	lysine exporter protein (LysE YggA)
H0N28_00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H0N28_00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H0N28_00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H0N28_00500	COG0753	catalase activity
H0N28_00550	COG0534	Mate efflux family protein
H0N28_00555	COG0436	Aminotransferase
H0N28_00560	COG2733	membrane
H0N28_00575	COG2918	glutathione biosynthetic process
H0N28_00610	COG0640	Transcriptional regulator
H0N28_00635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H0N28_00705	COG1525	nuclease
H0N28_00825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0N28_00875	COG1192	Involved in chromosome partitioning
H0N28_00890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0N28_00920	COG0739	heme binding
H0N28_01100	COG0501	Belongs to the peptidase M48B family
H0N28_01160	COG0589	response to stress
H0N28_01165	COG0659	secondary active sulfate transmembrane transporter activity
H0N28_01175	COG0606	chelatase, subunit chli
H0N28_01185	COG0347	Belongs to the P(II) protein family
H0N28_01190	COG0004	ammonium transporteR
H0N28_01200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0N28_01200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0N28_01240	COG0795	lipopolysaccharide-transporting ATPase activity
H0N28_01245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H0N28_01250	COG0793	Belongs to the peptidase S41A family
H0N28_01265	COG2197	response regulator
H0N28_01275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H0N28_01285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0N28_01290	COG4974	Belongs to the 'phage' integrase family
H0N28_01315	COG0772	Belongs to the SEDS family
H0N28_01320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0N28_01325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H0N28_01330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0N28_01355	COG0697	spore germination
H0N28_01360	COG1538	Outer membrane efflux protein
H0N28_01380	COG3275	phosphorelay sensor kinase activity
H0N28_01390	COG0181	hydroxymethylbilane synthase activity
H0N28_01435	COG1716	ATPase activity
H0N28_01440	COG0546	phosphoglycolate phosphatase activity
H0N28_01535	COG0596	Alpha beta hydrolase
H0N28_01540	COG2056	Na+-H+ antiporter family
H0N28_01555	COG0326	Molecular chaperone. Has ATPase activity
H0N28_01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H0N28_01635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H0N28_01640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0N28_01640	COG2169	Transcriptional regulator
H0N28_01670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H0N28_01680	COG0497	DNA recombination
H0N28_01695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0N28_01705	COG0237	dephospho-CoA kinase activity
H0N28_01750	COG0195	Participates in both transcription termination and antitermination
H0N28_01765	COG1320	monovalent cation:proton antiporter activity
H0N28_01770	COG2212	antiporter activity
H0N28_01775	COG1863	multisubunit Na H antiporter MnhE subunit
H0N28_01780	COG0651	ATP synthesis coupled electron transport
H0N28_01785	COG1006	Multisubunit Na H antiporter MnhC subunit
H0N28_01790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0N28_01790	COG2111	Na H antiporter
H0N28_01805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H0N28_01825	COG2226	methyltransferase
H0N28_01845	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H0N28_01850	COG1074	ATP-dependent DNA helicase activity
H0N28_01855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0N28_01860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0N28_01875	COG0598	Magnesium transport protein CorA
H0N28_01880	COG0789	Transcriptional regulator
H0N28_01885	COG0484	heat shock protein binding
H0N28_01900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0N28_01900	COG0475	glutathione-regulated potassium exporter activity
H0N28_01905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H0N28_01925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0N28_01935	COG4535	Mg2 and Co2 transporter CorC
H0N28_01940	COG0425	Belongs to the sulfur carrier protein TusA family
H0N28_01950	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H0N28_01950	COG0644	oxidoreductase
H0N28_01960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0N28_01975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0N28_01980	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H0N28_01990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0N28_01990	COG0493	'glutamate synthase
H0N28_02015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H0N28_02030	COG0534	Mate efflux family protein
H0N28_02040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0N28_02045	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_02050	COG0583	DNA-binding transcription factor activity
H0N28_02065	COG0318	PFAM AMP-dependent synthetase and ligase
H0N28_02070	COG1530	ribonuclease E activity
H0N28_02080	COG0546	phosphoglycolate phosphatase activity
H0N28_02085	COG2378	regulation of single-species biofilm formation
H0N28_02090	COG0625	glutathione transferase activity
H0N28_02100	COG0583	DNA-binding transcription factor activity
H0N28_02155	COG0473	3-isopropylmalate dehydrogenase activity
H0N28_02210	COG1301	dicarboxylic acid transport
H0N28_02220	COG1560	Kdo2-lipid A biosynthetic process
H0N28_02225	COG1280	lysine exporter protein (LysE YggA)
H0N28_02230	COG0488	(ABC) transporter
H0N28_02235	COG2900	Belongs to the SlyX family
H0N28_02245	COG1733	regulation of RNA biosynthetic process
H0N28_02270	COG0210	DNA helicase
H0N28_02275	COG0724	RNA recognition motif
H0N28_02320	COG0788	formyltetrahydrofolate deformylase activity
H0N28_02420	COG2813	Specifically methylates the guanine in position
H0N28_02420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0N28_02430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0N28_02440	COG4774	siderophore transport
H0N28_02450	COG0740	serine-type endopeptidase activity
H0N28_02470	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0N28_02470	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0N28_02475	COG0857	belongs to the CobB CobQ family
H0N28_02475	COG0280	phosphate acetyltransferase
H0N28_02480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H0N28_02490	COG0800	Aldolase
H0N28_02500	COG3265	gluconokinase activity
H0N28_02505	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_02515	COG2267	carboxylic ester hydrolase activity
H0N28_02530	COG0793	Belongs to the peptidase S41A family
H0N28_02565	COG1426	Protein conserved in bacteria
H0N28_02610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0N28_02620	COG0318	PFAM AMP-dependent synthetase and ligase
H0N28_02625	COG1216	Glycosyl transferase, family 2
H0N28_02635	COG2986	histidine ammonia-lyase
H0N28_02675	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_02680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H0N28_02700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0N28_02710	COG1162	GTPase activity
H0N28_02715	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H0N28_02730	COG1538	Outer membrane efflux protein
H0N28_02735	COG0577	efflux transmembrane transporter activity
H0N28_02735	COG1136	(ABC) transporter
H0N28_02740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N28_02765	COG0028	Belongs to the TPP enzyme family
H0N28_02770	COG0440	acetolactate synthase activity
H0N28_02820	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H0N28_02835	COG0084	hydrolase, TatD family'
H0N28_02845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H0N28_02855	COG0583	DNA-binding transcription factor activity
H0N28_02865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0N28_02870	COG2814	Major facilitator Superfamily
H0N28_02880	COG0697	spore germination
H0N28_02910	COG3622	Belongs to the hyi family
H0N28_02915	COG2084	Dehydrogenase
H0N28_02920	COG1024	Enoyl-CoA hydratase
H0N28_02925	COG0784	Response regulator, receiver
H0N28_02925	COG2205	protein histidine kinase activity
H0N28_02925	COG5002	protein histidine kinase activity
H0N28_02945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0N28_02955	COG3956	TIGRFAM MazG family protein
H0N28_02960	COG1555	photosystem II stabilization
H0N28_02965	COG0617	tRNA 3'-terminal CCA addition
H0N28_02970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H0N28_02990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0N28_02995	COG3028	Belongs to the UPF0307 family
H0N28_03000	COG0318	PFAM AMP-dependent synthetase and ligase
H0N28_03015	COG0625	glutathione transferase activity
H0N28_03020	COG1238	metal cluster binding
H0N28_03060	COG0072	phenylalanine-tRNA ligase activity
H0N28_03090	COG0248	Ppx GppA phosphatase
H0N28_03100	COG0037	tRNA processing
H0N28_03140	COG1764	response to oxidative stress
H0N28_03145	COG1846	Transcriptional regulator
H0N28_03155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0N28_03215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H0N28_03220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H0N28_03225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H0N28_03235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H0N28_03285	COG1214	PFAM Peptidase M22, glycoprotease
H0N28_03310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0N28_03315	COG0561	phosphatase activity
H0N28_03325	COG2132	Multicopper oxidase
H0N28_03345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0N28_03350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H0N28_03355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H0N28_03385	COG1063	alcohol dehydrogenase
H0N28_03390	COG0583	DNA-binding transcription factor activity
H0N28_03395	COG1960	acyl-CoA dehydrogenase activity
H0N28_03400	COG2814	Major facilitator Superfamily
H0N28_03405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0N28_03415	COG1053	succinate dehydrogenase
H0N28_03420	COG0583	DNA-binding transcription factor activity
H0N28_03435	COG0583	DNA-binding transcription factor activity
H0N28_03465	COG0583	DNA-binding transcription factor activity
H0N28_03480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N28_03525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0N28_03540	COG0745	RESPONSE REGULATOR receiver
H0N28_03580	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H0N28_03610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0N28_03615	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0N28_03640	COG0583	DNA-binding transcription factor activity
H0N28_03660	COG0668	transmembrane transport
H0N28_03670	COG2081	HI0933 family
H0N28_03675	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H0N28_03715	COG0489	protein tyrosine kinase activity
H0N28_03765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0N28_03775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0N28_03790	COG0730	response to heat
H0N28_03800	COG1196	nuclear chromosome segregation
H0N28_03820	COG2223	nitrite transmembrane transporter activity
H0N28_03825	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H0N28_03830	COG1877	trehalose-phosphatase activity
H0N28_03835	COG2226	methyltransferase
H0N28_03835	COG0596	Alpha beta hydrolase
H0N28_03835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0N28_03850	COG4106	trans-aconitate 2-methyltransferase activity
H0N28_03865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H0N28_03870	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H0N28_03875	COG0009	L-threonylcarbamoyladenylate synthase
H0N28_03880	COG3101	peptidyl-lysine hydroxylation
H0N28_03885	COG1399	metal-binding, possibly nucleic acid-binding protein
H0N28_03910	COG1652	LysM domain
H0N28_03915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0N28_03915	COG0352	thiamine-phosphate diphosphorylase activity
H0N28_03915	COG0351	phosphomethylpyrimidine kinase
H0N28_03925	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0N28_03955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0N28_03985	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H0N28_04000	COG0358	DNA primase activity
H0N28_04010	COG0564	pseudouridine synthase activity
H0N28_04035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0N28_04055	COG0583	DNA-binding transcription factor activity
H0N28_04060	COG0473	3-isopropylmalate dehydrogenase activity
H0N28_04070	COG0657	acetylesterase activity
H0N28_04080	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_04100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H0N28_04100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0N28_04115	COG1981	membrane
H0N28_04160	COG0456	acetyltransferase
H0N28_04170	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H0N28_04175	COG0492	ferredoxin-NADP+ reductase activity
H0N28_04180	COG1674	ftsk spoiiie
H0N28_04180	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0N28_04185	COG1280	lysine exporter protein (LysE YggA)
H0N28_04200	COG2894	cell division
H0N28_04215	COG0204	Acyl-transferase
H0N28_04220	COG2885	chlorophyll binding
H0N28_04225	COG0210	DNA helicase
H0N28_04235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0N28_04250	COG0121	glutamine amidotransferase
H0N28_04270	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0N28_04275	COG0735	belongs to the Fur family
H0N28_04300	COG0420	3'-5' exonuclease activity
H0N28_04320	COG1090	epimerase
H0N28_04335	COG2050	protein possibly involved in aromatic compounds catabolism
H0N28_04345	COG2814	Major facilitator Superfamily
H0N28_04350	COG0405	Gamma-glutamyltransferase
H0N28_04390	COG0477	Major facilitator Superfamily
H0N28_04395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0N28_04425	COG2040	homocysteine
H0N28_04450	COG1309	transcriptional regulator
H0N28_04455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0N28_04460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0N28_04470	COG1607	acyl-coa hydrolase
H0N28_04480	COG0523	cobalamin synthesis protein
H0N28_04490	COG4681	YaeQ
H0N28_04500	COG1649	PFAM Uncharacterised BCR, COG1649
H0N28_04500	COG0726	polysaccharide deacetylase
H0N28_04505	COG1215	transferase activity, transferring glycosyl groups
H0N28_04515	COG1024	Enoyl-CoA hydratase
H0N28_04530	COG1414	Transcriptional regulator
H0N28_04550	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_04560	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0N28_04565	COG2271	Major facilitator Superfamily
H0N28_04575	COG2267	carboxylic ester hydrolase activity
H0N28_04580	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_04595	COG0028	Belongs to the TPP enzyme family
H0N28_04605	COG0477	Major facilitator Superfamily
H0N28_04610	COG0242	peptide deformylase activity
H0N28_04615	COG2066	Belongs to the glutaminase family
H0N28_04620	COG2207	Transcriptional regulator
H0N28_04625	COG2223	nitrite transmembrane transporter activity
H0N28_04645	COG0583	DNA-binding transcription factor activity
H0N28_04650	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_04655	COG2271	Major facilitator Superfamily
H0N28_04660	COG3959	Transketolase, thiamine diphosphate binding domain
H0N28_04665	COG3958	Transketolase
H0N28_04675	COG0306	phosphate transporter
H0N28_04695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0N28_04740	COG4181	ATPase activity
H0N28_04745	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H0N28_04775	COG0583	DNA-binding transcription factor activity
H0N28_04785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N28_04790	COG1773	rubredoxin
H0N28_04840	COG2851	Citrate transporter
H0N28_04845	COG1253	flavin adenine dinucleotide binding
H0N28_04890	COG0804	urea catabolic process
H0N28_04900	COG0830	nickel cation binding
H0N28_04915	COG0742	ribosomal rna small subunit methyltransferase
H0N28_04920	COG0768	penicillin binding
H0N28_04945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H0N28_04950	COG2878	Part of a membrane complex involved in electron transport
H0N28_04955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0N28_04965	COG3384	dioxygenase
H0N28_04990	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H0N28_05030	COG0006	proline dipeptidase activity
H0N28_05035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N28_05040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N28_05060	COG1279	arginine transmembrane transporter activity
H0N28_05065	COG0583	DNA-binding transcription factor activity
H0N28_05105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0N28_05110	COG0741	lytic transglycosylase activity
H0N28_05110	COG1388	LysM domain
H0N28_05110	COG0741	lytic transglycosylase activity
H0N28_05110	COG1388	LysM domain
H0N28_05120	COG4174	ABC transporter (Permease)
H0N28_05125	COG4239	(ABC) transporter, permease
H0N28_05130	COG4172	Belongs to the ABC transporter superfamily
H0N28_05150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0N28_05160	COG2203	Gaf domain
H0N28_05160	COG5001	Diguanylate cyclase
H0N28_05160	COG3706	GGDEF domain
H0N28_05160	COG4251	negative regulation of phosphorylation
H0N28_05175	COG1902	pentaerythritol trinitrate reductase activity
H0N28_05175	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0N28_05210	COG0251	oxidation-reduction process
H0N28_05220	COG0583	DNA-binding transcription factor activity
H0N28_05265	COG1113	amino acid transport
H0N28_05275	COG0531	amino acid
H0N28_05295	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_05315	COG1113	amino acid transport
H0N28_05345	COG0697	spore germination
H0N28_05350	COG2721	sulfolactate sulfo-lyase activity
H0N28_05355	COG2271	Major facilitator Superfamily
H0N28_05360	COG4948	Mandelate Racemase Muconate Lactonizing
H0N28_05370	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_05375	COG2186	Transcriptional regulator
H0N28_05400	COG1960	acyl-CoA dehydrogenase activity
H0N28_05410	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_05415	COG1024	Enoyl-CoA hydratase
H0N28_05420	COG2814	Major facilitator Superfamily
H0N28_05435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N28_05480	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H0N28_05485	COG2072	flavoprotein involved in K transport
H0N28_05490	COG0300	oxidoreductase activity
H0N28_05500	COG1309	transcriptional regulator
H0N28_05505	COG1741	Belongs to the pirin family
H0N28_05520	COG2072	flavoprotein involved in K transport
H0N28_05530	COG2252	PERMEase
H0N28_05535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H0N28_05540	COG3038	cytochrome b561
H0N28_05550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H0N28_05560	COG0527	aspartate kinase activity
H0N28_05610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0N28_05615	COG4197	protein conserved in bacteria, prophage-related
H0N28_05695	COG5410	chromosome segregation
H0N28_05700	COG3567	Phage-associated protein, HI1409 family
H0N28_05720	COG3566	protein conserved in bacteria
H0N28_05855	COG0582	viral genome integration into host DNA
H0N28_05875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H0N28_05890	COG0667	Aldo Keto reductase
H0N28_05900	COG1765	OsmC-like protein
H0N28_05915	COG0542	response to heat
H0N28_05950	COG2885	chlorophyll binding
H0N28_05960	COG0625	glutathione transferase activity
H0N28_05965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H0N28_05985	COG3634	alkyl hydroperoxide reductase activity
H0N28_05995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H0N28_06005	COG0450	alkyl hydroperoxide reductase
H0N28_06010	COG1643	Atp-dependent helicase
H0N28_06025	COG2814	Major facilitator Superfamily
H0N28_06035	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_06040	COG0543	2 iron, 2 sulfur cluster binding
H0N28_06040	COG0633	Ferredoxin
H0N28_06045	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0N28_06050	COG4638	Rieske (2fe-2S)
H0N28_06055	COG0583	DNA-binding transcription factor activity
H0N28_06105	COG1570	exodeoxyribonuclease VII activity
H0N28_06135	COG1280	lysine exporter protein (LysE YggA)
H0N28_06140	COG1278	Cold shock
H0N28_06175	COG2814	Major facilitator Superfamily
H0N28_06210	COG0517	IMP dehydrogenase activity
H0N28_06210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H0N28_06215	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H0N28_06225	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H0N28_06230	COG1137	ATPase activity
H0N28_06235	COG1538	Outer membrane efflux protein
H0N28_06265	COG4122	O-methyltransferase activity
H0N28_06275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H0N28_06290	COG1522	sequence-specific DNA binding
H0N28_06305	COG1560	Kdo2-lipid A biosynthetic process
H0N28_06310	COG0598	Magnesium transport protein CorA
H0N28_06325	COG2814	Major facilitator Superfamily
H0N28_06345	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0N28_06380	COG0583	DNA-binding transcription factor activity
H0N28_06385	COG1914	H( )-stimulated, divalent metal cation uptake system
H0N28_06405	COG4770	biotin carboxylase activity
H0N28_06410	COG0038	chloride channel
H0N28_06420	COG1309	transcriptional regulator
H0N28_06430	COG1063	alcohol dehydrogenase
H0N28_06445	COG0439	Biotin carboxylase
H0N28_06450	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N28_06455	COG1733	regulation of RNA biosynthetic process
H0N28_06475	COG0864	Transcriptional regulator
H0N28_06485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0N28_06490	COG1116	anion transmembrane transporter activity
H0N28_06515	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0N28_06620	COG0590	tRNA wobble adenosine to inosine editing
H0N28_06625	COG2807	transmembrane transport
H0N28_06640	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H0N28_06650	COG0789	Transcriptional regulator
H0N28_06660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0N28_06680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0N28_06705	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_06710	COG0531	amino acid
H0N28_06715	COG1760	l-serine dehydratase
H0N28_06720	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_06720	COG2030	dehydratase
H0N28_06725	COG3396	Phenylacetate-CoA oxygenase
H0N28_06730	COG3460	Phenylacetate-CoA oxygenase
H0N28_06735	COG3396	Phenylacetate-CoA oxygenase
H0N28_06740	COG2151	metal-sulfur cluster biosynthetic enzyme
H0N28_06745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N28_06750	COG1024	Enoyl-CoA hydratase
H0N28_06755	COG1024	Enoyl-CoA hydratase
H0N28_06760	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0N28_06765	COG0183	Belongs to the thiolase family
H0N28_06770	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H0N28_06775	COG3327	negative regulation of DNA-templated transcription, initiation
H0N28_06785	COG2050	protein possibly involved in aromatic compounds catabolism
H0N28_06815	COG0753	catalase activity
H0N28_06820	COG3038	cytochrome b561
H0N28_06825	COG0583	DNA-binding transcription factor activity
H0N28_06835	COG1414	Transcriptional regulator
H0N28_06840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N28_06855	COG1840	ABC-type Fe3 transport system, periplasmic component
H0N28_06860	COG3842	ATPase activity
H0N28_06875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H0N28_06880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0N28_06900	COG0583	DNA-binding transcription factor activity
H0N28_06910	COG4770	biotin carboxylase activity
H0N28_06915	COG1024	Enoyl-CoA hydratase
H0N28_06920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0N28_06925	COG1960	acyl-CoA dehydrogenase activity
H0N28_06930	COG1309	transcriptional regulator
H0N28_06935	COG0318	PFAM AMP-dependent synthetase and ligase
H0N28_06955	COG0583	DNA-binding transcription factor activity
H0N28_07005	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_07045	COG2205	protein histidine kinase activity
H0N28_07045	COG0784	Response regulator, receiver
H0N28_07065	COG0765	amino acid transport
H0N28_07070	COG0765	amino acid transport
H0N28_07080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0N28_07085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0N28_07110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H0N28_07115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0N28_07120	COG1045	serine acetyltransferase
H0N28_07135	COG0583	DNA-binding transcription factor activity
H0N28_07140	COG0625	glutathione transferase activity
H0N28_07145	COG0625	glutathione transferase activity
H0N28_07150	COG0583	DNA-binding transcription factor activity
H0N28_07160	COG1346	cytolysis
H0N28_07165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N28_07180	COG2814	Major facilitator Superfamily
H0N28_07190	COG0583	DNA-binding transcription factor activity
H0N28_07200	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H0N28_07205	COG3052	prosthetic group binding
H0N28_07225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H0N28_07245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N28_07255	COG1294	oxidase, subunit
H0N28_07260	COG1271	oxidase subunit
H0N28_07280	COG0477	Major facilitator Superfamily
H0N28_07290	COG4521	taurine ABC transporter
H0N28_07295	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H0N28_07300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0N28_07305	COG2175	clavaminate synthase activity
H0N28_07315	COG1953	Uracil, thiamine, allantoin
H0N28_07325	COG0583	DNA-binding transcription factor activity
H0N28_07335	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H0N28_07350	COG0640	Transcriptional regulator
H0N28_07355	COG0798	PFAM Bile acid sodium symporter
H0N28_07360	COG0583	DNA-binding transcription factor activity
H0N28_07375	COG3634	alkyl hydroperoxide reductase activity
H0N28_07410	COG1301	dicarboxylic acid transport
H0N28_07415	COG0436	Aminotransferase
H0N28_07425	COG0386	Belongs to the glutathione peroxidase family
H0N28_07465	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0N28_07490	COG0012	GTP binding
H0N28_07495	COG2011	ABC-type metal ion transport system permease component
H0N28_07500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0N28_07510	COG1464	Belongs to the NlpA lipoprotein family
H0N28_07540	COG0765	amino acid transport
H0N28_07545	COG0765	amino acid transport
H0N28_07550	COG1126	abc transporter atp-binding protein
H0N28_07560	COG1522	sequence-specific DNA binding
H0N28_07575	COG1309	transcriptional regulator
H0N28_07595	COG0583	DNA-binding transcription factor activity
H0N28_07605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0N28_07615	COG0697	spore germination
H0N28_07640	COG3121	Chaperone
H0N28_07645	COG3539	Fimbrial protein
H0N28_07670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H0N28_07670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H0N28_07715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H0N28_07725	COG2353	YceI-like domain
H0N28_07735	COG3698	Phosphodiester glycosidase
H0N28_07750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H0N28_07755	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0N28_07755	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0N28_07755	COG0506	proline dehydrogenase activity
H0N28_07765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0N28_07770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H0N28_07790	COG1132	(ABC) transporter
H0N28_07795	COG3122	Protein conserved in bacteria
H0N28_07800	COG3619	membrane
H0N28_07810	COG0640	Transcriptional regulator
H0N28_07820	COG2850	peptidyl-arginine hydroxylation
H0N28_07825	COG0424	maF-like protein
H0N28_07845	COG0191	fructose-bisphosphate aldolase activity
H0N28_07850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0N28_07865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H0N28_07875	COG1192	Involved in chromosome partitioning
H0N28_07880	COG1475	DNA binding
H0N28_07885	COG0811	peptide transport
H0N28_07895	COG1132	(ABC) transporter
H0N28_07900	COG1663	tetraacyldisaccharide 4'-kinase activity
H0N28_07920	COG0084	hydrolase, TatD family'
H0N28_07985	COG0776	regulation of translation
H0N28_08015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H0N28_08085	COG0305	Participates in initiation and elongation during chromosome replication
H0N28_08175	COG4695	Portal protein
H0N28_08280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H0N28_08330	COG0339	signal peptide processing
H0N28_08340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0N28_08375	COG0702	epimerase
H0N28_08380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0N28_08400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0N28_08430	COG0316	Belongs to the HesB IscA family
H0N28_08435	COG0822	iron-sulfur transferase activity
H0N28_08460	COG0776	regulation of translation
H0N28_08470	COG2207	Transcriptional regulator
H0N28_08475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0N28_08480	COG1960	acyl-CoA dehydrogenase activity
H0N28_08485	COG1960	acyl-CoA dehydrogenase activity
H0N28_08500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H0N28_08515	COG2814	Major facilitator Superfamily
H0N28_08520	COG4264	IucA IucC family
H0N28_08525	COG4264	IucA IucC family
H0N28_08535	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0N28_08565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0N28_08580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H0N28_08585	COG0406	alpha-ribazole phosphatase activity
H0N28_08600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0N28_08605	COG0730	response to heat
H0N28_08625	COG4773	Receptor
H0N28_08630	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0N28_08645	COG1131	(ABC) transporter
H0N28_08650	COG0842	Transport permease protein
H0N28_08655	COG0842	Transport permease protein
H0N28_08710	COG2226	methyltransferase
H0N28_08735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H0N28_08740	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H0N28_08770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0N28_08780	COG0133	tryptophan synthase activity
H0N28_08795	COG3706	GGDEF domain
H0N28_08810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0N28_08815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H0N28_08820	COG0022	dehydrogenase e1 component
H0N28_08825	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0N28_08830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0N28_08840	COG1063	alcohol dehydrogenase
H0N28_08845	COG3781	membrane
H0N28_08855	COG3453	Protein conserved in bacteria
H0N28_08855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0N28_08880	COG3708	Transcriptional regulator
H0N28_08880	COG2207	Transcriptional regulator
H0N28_08885	COG1733	regulation of RNA biosynthetic process
H0N28_08890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H0N28_08900	COG2188	Transcriptional regulator
H0N28_08915	COG4521	taurine ABC transporter
H0N28_08920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0N28_08940	COG0477	Major facilitator Superfamily
H0N28_08950	COG1027	Aspartate ammonia-lyase
H0N28_08965	COG0583	DNA-binding transcription factor activity
H0N28_08970	COG0583	DNA-binding transcription factor activity
H0N28_08975	COG0183	Belongs to the thiolase family
H0N28_08980	COG2031	fatty acid transporter
H0N28_08995	COG0583	DNA-binding transcription factor activity
H0N28_09015	COG1309	transcriptional regulator
H0N28_09025	COG2610	gluconate transmembrane transporter activity
H0N28_09030	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_09035	COG2207	Transcriptional regulator
H0N28_09050	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_09060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N28_09095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0N28_09100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N28_09105	COG0745	RESPONSE REGULATOR receiver
H0N28_09110	COG2205	protein histidine kinase activity
H0N28_09125	COG2207	Transcriptional regulator
H0N28_09175	COG2856	Zn peptidase
H0N28_09210	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H0N28_09305	COG1120	ATPase activity
H0N28_09310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0N28_09320	COG1064	alcohol dehydrogenase
H0N28_09325	COG2207	Transcriptional regulator
H0N28_09330	COG2084	Dehydrogenase
H0N28_09340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0N28_09345	COG0583	DNA-binding transcription factor activity
H0N28_09355	COG0129	dihydroxy-acid dehydratase activity
H0N28_09360	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_09375	COG1566	PFAM secretion protein HlyD family protein
H0N28_09390	COG0583	DNA-binding transcription factor activity
H0N28_09405	COG2188	Transcriptional regulator
H0N28_09485	COG0318	PFAM AMP-dependent synthetase and ligase
H0N28_09495	COG1960	acyl-CoA dehydrogenase activity
H0N28_09505	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_09510	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_09515	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_09520	COG0583	DNA-binding transcription factor activity
H0N28_09525	COG1309	transcriptional regulator
H0N28_09550	COG0789	Transcriptional regulator
H0N28_09560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H0N28_09570	COG1902	pentaerythritol trinitrate reductase activity
H0N28_09570	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0N28_09585	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_09605	COG2186	Transcriptional regulator
H0N28_09615	COG0583	DNA-binding transcription factor activity
H0N28_09620	COG4948	Mandelate Racemase Muconate Lactonizing
H0N28_09625	COG4829	muconolactone delta-isomerase
H0N28_09635	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0N28_09640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0N28_09645	COG0183	Belongs to the thiolase family
H0N28_09650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0N28_09660	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_09680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N28_09690	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_09700	COG4638	Rieske (2fe-2S)
H0N28_09720	COG0154	amidase activity
H0N28_09730	COG2814	Major facilitator Superfamily
H0N28_09755	COG1960	acyl-CoA dehydrogenase activity
H0N28_09760	COG0583	DNA-binding transcription factor activity
H0N28_09765	COG1414	Transcriptional regulator
H0N28_09780	COG2391	methyltransferase activity
H0N28_09790	COG4993	Dehydrogenase
H0N28_09795	COG3659	wide pore channel activity
H0N28_09800	COG3420	alginic acid biosynthetic process
H0N28_09805	COG0710	3-dehydroquinate dehydratase activity
H0N28_09810	COG3485	protocatechuate 3,4-dioxygenase
H0N28_09815	COG3485	protocatechuate 3,4-dioxygenase
H0N28_09820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0N28_09825	COG2271	Major facilitator Superfamily
H0N28_09830	COG0596	Alpha beta hydrolase
H0N28_09835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H0N28_09840	COG0183	Belongs to the thiolase family
H0N28_09845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0N28_09850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0N28_09860	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H0N28_09865	COG2323	membrane
H0N28_09910	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0N28_09910	COG1902	pentaerythritol trinitrate reductase activity
H0N28_09935	COG0542	response to heat
H0N28_09940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H0N28_09970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0N28_09975	COG0569	domain protein
H0N28_09980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H0N28_09995	COG4774	siderophore transport
H0N28_10000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0N28_10010	COG1585	Membrane protein implicated in regulation of membrane protease activity
H0N28_10025	COG1294	oxidase, subunit
H0N28_10030	COG4890	Cyd operon protein YbgT
H0N28_10045	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H0N28_10055	COG0552	protein localization to endoplasmic reticulum
H0N28_10080	COG0517	IMP dehydrogenase activity
H0N28_10080	COG0516	GMP reductase activity
H0N28_10085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0N28_10090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H0N28_10100	COG0583	DNA-binding transcription factor activity
H0N28_10105	COG0024	Methionine aminopeptidase
H0N28_10135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0N28_10135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0N28_10140	COG1105	Belongs to the carbohydrate kinase PfkB family
H0N28_10145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0N28_10145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0N28_10145	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H0N28_10160	COG5001	Diguanylate cyclase
H0N28_10160	COG3300	MHYT domain
H0N28_10175	COG2135	peptidase activity
H0N28_10180	COG0659	secondary active sulfate transmembrane transporter activity
H0N28_10195	COG1113	amino acid transport
H0N28_10205	COG1522	sequence-specific DNA binding
H0N28_10230	COG1011	Hydrolase
H0N28_10235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H0N28_10245	COG2137	regulation of response to DNA damage stimulus
H0N28_10260	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0N28_10280	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0N28_10295	COG0575	Belongs to the CDS family
H0N28_10300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H0N28_10325	COG3852	Histidine kinase
H0N28_10330	COG2204	response regulator
H0N28_10385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0N28_10390	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H0N28_10410	COG0697	spore germination
H0N28_10415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N28_10425	COG0303	'Molybdopterin
H0N28_10430	COG0521	Mo-molybdopterin cofactor biosynthetic process
H0N28_10430	COG0315	cyclic pyranopterin monophosphate synthase activity
H0N28_10445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H0N28_10450	COG0243	molybdopterin cofactor binding
H0N28_10460	COG0243	molybdopterin cofactor binding
H0N28_10465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N28_10470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N28_10470	COG2146	nitrite reductase [NAD(P)H] activity
H0N28_10480	COG0745	RESPONSE REGULATOR receiver
H0N28_10485	COG1116	anion transmembrane transporter activity
H0N28_10485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0N28_10505	COG0511	ligase activity, forming carbon-carbon bonds
H0N28_10520	COG2814	Major facilitator Superfamily
H0N28_10535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0N28_10605	COG1598	PFAM Uncharacterised protein family UPF0150
H0N28_10710	COG5410	chromosome segregation
H0N28_10750	COG3617	BRO family, N-terminal domain
H0N28_10895	COG0069	glutamate synthase activity
H0N28_10915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H0N28_10925	COG1454	alcohol dehydrogenase
H0N28_10930	COG0824	Thioesterase
H0N28_10940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H0N28_10955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0N28_10960	COG2030	dehydratase
H0N28_10970	COG0183	Belongs to the thiolase family
H0N28_10980	COG0583	DNA-binding transcription factor activity
H0N28_10985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0N28_10995	COG1522	sequence-specific DNA binding
H0N28_11000	COG3135	benzoate transporter
H0N28_11010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H0N28_11030	COG0589	response to stress
H0N28_11035	COG0488	(ABC) transporter
H0N28_11055	COG4773	Receptor
H0N28_11085	COG0668	transmembrane transport
H0N28_11095	COG1309	transcriptional regulator
H0N28_11110	COG1605	Chorismate mutase
H0N28_11150	COG0308	aminopeptidase N
H0N28_11175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0N28_11180	COG1454	alcohol dehydrogenase
H0N28_11200	COG0531	amino acid
H0N28_11205	COG4303	Ethanolamine ammonia lyase large subunit
H0N28_11210	COG4302	ethanolamine ammonia-lyase activity
H0N28_11215	COG0519	Catalyzes the synthesis of GMP from XMP
H0N28_11215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0N28_11220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0N28_11245	COG0697	spore germination
H0N28_11250	COG1923	regulation of RNA biosynthetic process
H0N28_11260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H0N28_11265	COG0802	atpase or kinase
H0N28_11285	COG1187	pseudouridine synthase activity
H0N28_11300	COG0583	DNA-binding transcription factor activity
H0N28_11315	COG2814	Major facilitator Superfamily
H0N28_11320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0N28_11345	COG0729	surface antigen
H0N28_11365	COG0174	glutamine synthetase
H0N28_11370	COG0745	RESPONSE REGULATOR receiver
H0N28_11375	COG2205	protein histidine kinase activity
H0N28_11380	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H0N28_11385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H0N28_11390	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H0N28_11400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H0N28_11415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N28_11420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0N28_11425	COG1960	acyl-CoA dehydrogenase activity
H0N28_11455	COG0583	DNA-binding transcription factor activity
H0N28_11470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0N28_11480	COG3658	cytochrome
H0N28_11485	COG1215	transferase activity, transferring glycosyl groups
H0N28_11490	COG0726	polysaccharide deacetylase
H0N28_11490	COG1649	PFAM Uncharacterised BCR, COG1649
H0N28_11515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H0N28_11520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0N28_11530	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H0N28_11555	COG0305	Participates in initiation and elongation during chromosome replication
H0N28_11560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0N28_11570	COG1305	Transglutaminase-like
H0N28_11580	COG2308	Evidence 4 Homologs of previously reported genes of
H0N28_11610	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H0N28_11615	COG0138	bifunctional purine biosynthesis protein purh
H0N28_11620	COG0151	Belongs to the GarS family
H0N28_11630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0N28_11635	COG2011	ABC-type metal ion transport system permease component
H0N28_11640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0N28_11650	COG1301	dicarboxylic acid transport
H0N28_11680	COG1794	racemase activity, acting on amino acids and derivatives
H0N28_11695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0N28_11695	COG3008	intermembrane lipid transfer
H0N28_11700	COG2995	paraquat-inducible protein a
H0N28_11730	COG1051	belongs to the nudix hydrolase family
H0N28_11735	COG0477	Major facilitator Superfamily
H0N28_11785	COG2186	Transcriptional regulator
H0N28_11795	COG0786	glutamate:sodium symporter activity
H0N28_11800	COG3243	poly(R)-hydroxyalkanoic acid synthase
H0N28_11825	COG3111	PFAM Bacterial OB fold (BOF) protein
H0N28_11895	COG0515	serine threonine protein kinase
H0N28_11895	COG2815	serine threonine protein kinase
H0N28_11925	COG1610	YqeY-like protein
H0N28_11930	COG4783	chaperone-mediated protein folding
H0N28_11955	COG1286	toxin biosynthetic process
H0N28_11985	COG0778	Nitroreductase
H0N28_11995	COG0513	Belongs to the DEAD box helicase family
H0N28_12015	COG2363	Small membrane protein
H0N28_12045	COG4650	regulator
H0N28_12050	COG1234	tRNA 3'-trailer cleavage
H0N28_12055	COG1690	Belongs to the RtcB family
H0N28_12075	COG2195	Cleaves the N-terminal amino acid of tripeptides
H0N28_12085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H0N28_12095	COG2819	hydrolase of the alpha beta superfamily
H0N28_12100	COG1960	acyl-CoA dehydrogenase activity
H0N28_12105	COG1301	dicarboxylic acid transport
H0N28_12110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0N28_12115	COG3139	Protein of unknown function (DUF1315)
H0N28_12120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H0N28_12125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0N28_12135	COG0494	nUDIX hydrolase
H0N28_12145	COG0642	Histidine kinase
H0N28_12170	COG1720	tRNA m6t6A37 methyltransferase activity
H0N28_12185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N28_12190	COG0826	peptidase U32
H0N28_12195	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0N28_12205	COG4598	ABC transporter
H0N28_12210	COG4160	amino acid transport
H0N28_12215	COG4215	(ABC) transporter
H0N28_12230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N28_12275	COG1131	(ABC) transporter
H0N28_12280	COG0842	Transport permease protein
H0N28_12295	COG0772	Belongs to the SEDS family
H0N28_12300	COG2951	lytic endotransglycosylase activity
H0N28_12325	COG2207	Transcriptional regulator
H0N28_12340	COG0052	Belongs to the universal ribosomal protein uS2 family
H0N28_12345	COG0024	Methionine aminopeptidase
H0N28_12355	COG2223	nitrite transmembrane transporter activity
H0N28_12365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0N28_12370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0N28_12375	COG1960	acyl-CoA dehydrogenase activity
H0N28_12390	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H0N28_12395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H0N28_12400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0N28_12420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0N28_12425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H0N28_12430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H0N28_12465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H0N28_12475	COG0174	glutamine synthetase
H0N28_12490	COG0512	Glutamine amidotransferase of anthranilate synthase
H0N28_12495	COG0308	aminopeptidase N
H0N28_12525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0N28_12535	COG0302	gtp cyclohydrolase
H0N28_12555	COG3739	integral membrane protein
H0N28_12580	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H0N28_12585	COG1132	(ABC) transporter
H0N28_12590	COG1132	(ABC) transporter
H0N28_12600	COG3433	isochorismatase activity
H0N28_12600	COG1535	isochorismatase
H0N28_12605	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0N28_12610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N28_12620	COG4774	siderophore transport
H0N28_12625	COG4607	ABC-type enterochelin transport system periplasmic component
H0N28_12630	COG4604	ABC transporter, ATP-binding protein
H0N28_12635	COG4605	iron ion homeostasis
H0N28_12640	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0N28_12645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N28_12660	COG2964	Protein conserved in bacteria
H0N28_12670	COG1741	Belongs to the pirin family
H0N28_12710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0N28_12720	COG0596	Alpha beta hydrolase
H0N28_12735	COG0583	DNA-binding transcription factor activity
H0N28_12740	COG1335	isochorismatase
H0N28_12780	COG2879	small protein
H0N28_12785	COG1966	Carbon starvation protein
H0N28_12805	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H0N28_12830	COG1067	ATP-dependent peptidase activity
H0N28_12835	COG0583	DNA-binding transcription factor activity
H0N28_12860	COG1686	Belongs to the peptidase S11 family
H0N28_12865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H0N28_12900	COG0616	signal peptide processing
H0N28_12905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H0N28_12915	COG0573	inorganic phosphate transmembrane transporter activity
H0N28_12920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H0N28_12925	COG1113	amino acid transport
H0N28_12930	COG3961	Belongs to the TPP enzyme family
H0N28_12935	COG1522	sequence-specific DNA binding
H0N28_12945	COG0076	glutamate decarboxylase activity
H0N28_12950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0N28_12965	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N28_12975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N28_13010	COG0352	thiamine-phosphate diphosphorylase activity
H0N28_13035	COG0612	Peptidase, M16
H0N28_13045	COG1823	symporter activity
H0N28_13050	COG0583	DNA-binding transcription factor activity
H0N28_13055	COG0477	Major facilitator Superfamily
H0N28_13080	COG1187	pseudouridine synthase activity
H0N28_13095	COG1686	Belongs to the peptidase S11 family
H0N28_13100	COG1252	NADH dehydrogenase
H0N28_13110	COG0415	Belongs to the DNA photolyase family
H0N28_13125	COG1215	transferase activity, transferring glycosyl groups
H0N28_13155	COG2070	2-Nitropropane dioxygenase
H0N28_13210	COG0556	nucleotide-excision repair
H0N28_13230	COG0436	Aminotransferase
H0N28_13240	COG0443	Heat shock 70 kDa protein
H0N28_13270	COG4221	oxidoreductase activity
H0N28_13280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H0N28_13285	COG1381	Involved in DNA repair and RecF pathway recombination
H0N28_13295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H0N28_13310	COG0681	Belongs to the peptidase S26 family
H0N28_13320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H0N28_13330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0N28_13350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H0N28_13355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0N28_13360	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H0N28_13370	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H0N28_13375	COG4208	sulfate ABC transporter
H0N28_13380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H0N28_13385	COG0583	DNA-binding transcription factor activity
H0N28_13390	COG4625	pathogenesis
H0N28_13405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H0N28_13420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0N28_13430	COG1051	belongs to the nudix hydrolase family
H0N28_13430	COG1056	cytidyltransferase-related domain
H0N28_13435	COG1024	Enoyl-CoA hydratase
H0N28_13505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N28_13515	COG0534	Mate efflux family protein
H0N28_13530	COG4774	siderophore transport
H0N28_13535	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H0N28_13555	COG0019	diaminopimelate decarboxylase activity
H0N28_13560	COG3486	L-lysine 6-monooxygenase (NADPH) activity
H0N28_13565	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0N28_13570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N28_13575	COG3433	isochorismatase activity
H0N28_13575	COG2226	methyltransferase
H0N28_13575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N28_13580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N28_13585	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_13590	COG1535	isochorismatase
H0N28_13590	COG3433	isochorismatase activity
H0N28_13595	COG1169	isochorismate synthase
H0N28_13620	COG0047	phosphoribosylformylglycinamidine synthase activity
H0N28_13620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H0N28_13640	COG1473	amidohydrolase
H0N28_13645	COG0824	Thioesterase
H0N28_13665	COG0823	Involved in the tonB-independent uptake of proteins
H0N28_13685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0N28_13720	COG0628	permease
H0N28_13730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H0N28_13735	COG0596	Alpha beta hydrolase
H0N28_13740	COG0616	signal peptide processing
H0N28_13740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H0N28_13750	COG2333	competence protein COMEC
H0N28_13750	COG0658	competence protein
H0N28_13755	COG1136	(ABC) transporter
H0N28_13760	COG4591	ABC-type transport system involved in lipoprotein release permease component
H0N28_13795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N28_13815	COG0463	Glycosyl transferase, family 2
H0N28_13845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H0N28_13850	COG1280	lysine exporter protein (LysE YggA)
H0N28_13860	COG0019	diaminopimelate decarboxylase activity
H0N28_13870	COG1113	amino acid transport
H0N28_13885	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H0N28_13895	COG3339	Conserved Protein
H0N28_13900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H0N28_13905	COG0243	molybdopterin cofactor binding
H0N28_13910	COG1929	Belongs to the glycerate kinase type-1 family
H0N28_13925	COG0778	Nitroreductase
H0N28_13980	COG3811	Belongs to the UPF0386 family
H0N28_13990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N28_14005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0N28_14025	COG0741	lytic transglycosylase activity
H0N28_14045	COG0584	glycerophosphoryl diester phosphodiesterase
H0N28_14050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0N28_14070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0N28_14075	COG1597	lipid kinase activity
H0N28_14090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H0N28_14095	COG0477	Major facilitator Superfamily
H0N28_14145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H0N28_14150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0N28_14175	COG0505	Belongs to the CarA family
H0N28_14190	COG1309	transcriptional regulator
H0N28_14195	COG0251	oxidation-reduction process
H0N28_14205	COG0589	response to stress
H0N28_14220	COG2843	Capsule synthesis protein
H0N28_14240	COG2321	neutral zinc metallopeptidase
H0N28_14245	COG2354	Protein conserved in bacteria
H0N28_14265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0N28_14290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0N28_14295	COG1053	succinate dehydrogenase
H0N28_14300	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H0N28_14305	COG2009	succinate dehydrogenase
H0N28_14345	COG2921	Belongs to the UPF0250 family
H0N28_14350	COG0321	lipoyl(octanoyl) transferase activity
H0N28_14365	COG0531	amino acid
H0N28_14375	COG1733	regulation of RNA biosynthetic process
H0N28_14380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H0N28_14385	COG1648	precorrin-2 dehydrogenase activity
H0N28_14385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H0N28_14400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H0N28_14430	COG0671	phosphoesterase, PA-phosphatase related
H0N28_14435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N28_14445	COG1538	Outer membrane efflux protein
H0N28_14450	COG0393	Putative heavy-metal-binding
H0N28_14455	COG0393	Putative heavy-metal-binding
H0N28_14465	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_14475	COG0525	valine-tRNA ligase activity
H0N28_14495	COG0583	DNA-binding transcription factor activity
H0N28_14500	COG0004	ammonium transporteR
H0N28_14510	COG0642	Histidine kinase
H0N28_14515	COG0745	RESPONSE REGULATOR receiver
H0N28_14520	COG2194	sulfuric ester hydrolase activity
H0N28_14540	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0N28_14555	COG2315	Protein conserved in bacteria
H0N28_14560	COG0142	geranyltranstransferase activity
H0N28_14565	COG2828	Protein conserved in bacteria
H0N28_14570	COG1113	amino acid transport
H0N28_14590	COG2207	Transcriptional regulator
H0N28_14615	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N28_14625	COG0560	Phosphoserine phosphatase
H0N28_14635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N28_14645	COG1530	ribonuclease E activity
H0N28_14650	COG0424	maF-like protein
H0N28_14655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H0N28_14660	COG1792	Involved in formation and maintenance of cell shape
H0N28_14665	COG1077	Cell shape determining protein MreB Mrl
H0N28_14670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0N28_14680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0N28_14705	COG3590	peptidase
H0N28_14710	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H0N28_14715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0N28_14720	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0N28_14725	COG1115	amino acid carrier protein
H0N28_14745	COG2814	Major facilitator Superfamily
H0N28_14750	COG1289	transmembrane transporter activity
H0N28_14760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H0N28_14800	COG1376	ErfK ybiS ycfS ynhG family protein
H0N28_14805	COG2832	Protein of unknown function (DUF454)
H0N28_14815	COG5510	response to toxic substance
H0N28_14835	COG0840	transmembrane signaling receptor activity
H0N28_14875	COG3422	double-strand break repair
H0N28_14880	COG2824	Alkylphosphonate utilization operon protein PhnA
H0N28_14885	COG3189	MarR family transcriptional regulator
H0N28_14895	COG0354	folic acid binding
H0N28_14900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0N28_14910	COG0679	Auxin Efflux Carrier
H0N28_14915	COG1902	pentaerythritol trinitrate reductase activity
H0N28_14920	COG4772	TonB-dependent receptor
H0N28_14925	COG2094	Belongs to the DNA glycosylase MPG family
H0N28_14950	COG1217	gtp-binding protein TYPA
H0N28_14955	COG2233	PERMEase
H0N28_14965	COG0833	amino acid
H0N28_14970	COG1690	Belongs to the RtcB family
H0N28_14990	COG0183	Belongs to the thiolase family
H0N28_15010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N28_15030	COG2207	Transcriptional regulator
H0N28_15035	COG0183	Belongs to the thiolase family
H0N28_15055	COG2153	protein acetylation
H0N28_15065	COG1272	protein, Hemolysin III
H0N28_15070	COG0477	Major facilitator Superfamily
H0N28_15085	COG0450	alkyl hydroperoxide reductase
H0N28_15105	COG0285	dihydrofolate synthase activity
H0N28_15150	COG4206	TonB-dependent receptor
H0N28_15155	COG2096	Adenosyltransferase
H0N28_15175	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H0N28_15180	COG0745	RESPONSE REGULATOR receiver
H0N28_15185	COG2205	protein histidine kinase activity
H0N28_15195	COG1960	acyl-CoA dehydrogenase activity
H0N28_15200	COG1960	acyl-CoA dehydrogenase activity
H0N28_15265	COG0438	transferase activity, transferring glycosyl groups
H0N28_15270	COG0463	Glycosyl transferase, family 2
H0N28_15275	COG0726	polysaccharide deacetylase
H0N28_15295	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H0N28_15300	COG2205	protein histidine kinase activity
H0N28_15315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0N28_15340	COG0582	viral genome integration into host DNA
H0N28_15370	COG1862	Preprotein translocase
H0N28_15380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0N28_15385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H0N28_15395	COG3781	membrane
H0N28_15400	COG0613	PHP domain protein
H0N28_15410	COG2350	Protein conserved in bacteria
H0N28_15435	COG0582	viral genome integration into host DNA
H0N28_15485	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0N28_15510	COG2132	Multicopper oxidase
H0N28_15525	COG2205	protein histidine kinase activity
H0N28_15605	COG3013	Belongs to the UPF0304 family
H0N28_15635	COG1607	acyl-coa hydrolase
H0N28_15695	COG2199	diguanylate cyclase activity
H0N28_15705	COG1408	metallophosphoesterase
H0N28_15710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0N28_15720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H0N28_15740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0N28_15745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H0N28_15750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H0N28_15760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0N28_15770	COG2969	positive regulation of protein catabolic process
H0N28_15790	COG1960	acyl-CoA dehydrogenase activity
H0N28_15795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0N28_15810	COG1309	transcriptional regulator
H0N28_15815	COG1960	acyl-CoA dehydrogenase activity
H0N28_15860	COG1183	phosphatidylcholine synthase activity
H0N28_15865	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H0N28_15895	COG0739	heme binding
H0N28_15895	COG0741	lytic transglycosylase activity
H0N28_15895	COG1196	nuclear chromosome segregation
H0N28_15905	COG1702	phosphate starvation-inducible protein PhoH
H0N28_15940	COG1295	ribonuclease BN
H0N28_15945	COG0697	spore germination
H0N28_15950	COG2169	Transcriptional regulator
H0N28_15955	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0N28_16000	COG0557	exoribonuclease II activity
H0N28_16005	COG0339	signal peptide processing
H0N28_16010	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H0N28_16040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H0N28_16045	COG1960	acyl-CoA dehydrogenase activity
H0N28_16200	COG0626	cystathionine gamma-synthase activity
H0N28_16205	COG0433	COG0433 Predicted ATPase
H0N28_16215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N28_16215	COG1017	nitric oxide dioxygenase activity
H0N28_16220	COG1959	2 iron, 2 sulfur cluster binding
H0N28_16235	COG1301	dicarboxylic acid transport
H0N28_16240	COG1946	Acyl-CoA thioesterase
H0N28_16260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H0N28_16265	COG1040	competence protein
H0N28_16270	COG0494	nUDIX hydrolase
H0N28_16280	COG0598	Magnesium transport protein CorA
H0N28_16290	COG2854	intermembrane phospholipid transfer
H0N28_16300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H0N28_16305	COG1127	ABC transporter
H0N28_16315	COG0513	Belongs to the DEAD box helicase family
H0N28_16335	COG0408	coproporphyrinogen oxidase activity
H0N28_16350	COG1960	acyl-CoA dehydrogenase activity
H0N28_16360	COG1983	PspC domain protein
H0N28_16365	COG0517	IMP dehydrogenase activity
H0N28_16415	COG0583	DNA-binding transcription factor activity
H0N28_16455	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_16465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0N28_16470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0N28_16475	COG0833	amino acid
H0N28_16505	COG1192	Involved in chromosome partitioning
H0N28_16510	COG0628	permease
H0N28_16520	COG1289	transmembrane transporter activity
H0N28_16535	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N28_16540	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H0N28_16550	COG0277	FAD linked oxidase domain protein
H0N28_16555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0N28_16580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H0N28_16585	COG5380	lipid catabolic process
H0N28_16605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H0N28_16655	COG0194	GDP metabolic process
H0N28_16670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0N28_16690	COG3307	-O-antigen
H0N28_16695	COG4969	Belongs to the N-Me-Phe pilin family
H0N28_16705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H0N28_16710	COG1704	LemA family
H0N28_16720	COG0493	'glutamate synthase
H0N28_16725	COG0067	glutamate synthase
H0N28_16725	COG0069	glutamate synthase activity
H0N28_16725	COG0070	glutamate synthase
H0N28_16775	COG2226	methyltransferase
H0N28_16790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H0N28_16795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0N28_16840	COG0833	amino acid
H0N28_16905	COG0488	(ABC) transporter
H0N28_16930	COG4221	oxidoreductase activity
H0N28_16935	COG0659	secondary active sulfate transmembrane transporter activity
H0N28_16960	COG0427	acetyl-CoA hydrolase
H0N28_16990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H0N28_17020	COG2329	Antibiotic biosynthesis monooxygenase
H0N28_17035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H0N28_17090	COG2207	Transcriptional regulator
H0N28_17095	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H0N28_17115	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N28_17120	COG1733	regulation of RNA biosynthetic process
H0N28_17150	COG1733	regulation of RNA biosynthetic process
H0N28_17195	COG0583	DNA-binding transcription factor activity
H0N28_17200	COG2814	Major facilitator Superfamily
H0N28_17240	COG1335	isochorismatase
H0N28_17250	COG1012	belongs to the aldehyde dehydrogenase family
H0N28_17255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0N28_17265	COG1113	amino acid transport
H0N28_17275	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0N28_17290	COG2814	Major facilitator Superfamily
H0N28_17300	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0N28_17300	COG0352	thiamine-phosphate diphosphorylase activity
H0N28_17300	COG0351	phosphomethylpyrimidine kinase
H0N28_17320	COG1309	transcriptional regulator
H0N28_17325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H0N28_17340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0N28_17350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0N28_17355	COG3162	membrane
H0N28_17360	COG2205	protein histidine kinase activity
H0N28_17360	COG2198	Histidine kinase
H0N28_17360	COG0784	Response regulator, receiver
H0N28_17385	COG1522	sequence-specific DNA binding
H0N28_17390	COG1335	isochorismatase
H0N28_17395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0N28_17405	COG0668	transmembrane transport
H0N28_17415	COG1519	Transferase
H0N28_17420	COG1902	pentaerythritol trinitrate reductase activity
H0N28_17440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H0N28_17465	COG0426	domain, Protein
H0N28_17465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N28_17470	COG4774	siderophore transport
H0N28_17475	COG2119	membrane
H0N28_17485	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0N28_17495	COG4942	peptidase
H0N28_17510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H0N28_17520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H0N28_17540	COG0189	ligase activity
H0N28_17565	COG0708	Exodeoxyribonuclease III
H0N28_17570	COG1393	Belongs to the ArsC family
H0N28_17585	COG3706	GGDEF domain
H0N28_17620	COG2351	hydroxyisourate hydrolase activity
H0N28_17625	COG2233	PERMEase
H0N28_17635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N28_17645	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H0N28_17655	COG3150	esterase
H0N28_17735	COG4691	Plasmid stability protein
H0N28_17770	COG0798	PFAM Bile acid sodium symporter
H0N28_17855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H0N28_17885	COG0659	secondary active sulfate transmembrane transporter activity
H0N28_17890	COG0589	response to stress
H0N28_17940	COG0606	chelatase, subunit chli
H0N28_17945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N28_17955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0N28_17970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H0N28_17985	COG0318	PFAM AMP-dependent synthetase and ligase
H0N28_17995	COG0477	Major facilitator Superfamily
H0N28_18000	COG2860	membrane
H0N28_18005	COG3012	SEC-C Motif Domain Protein
H0N28_18010	COG1253	flavin adenine dinucleotide binding
H0N28_18020	COG0477	Major facilitator Superfamily
H0N28_18030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0N28_18065	COG0655	NAD(P)H dehydrogenase (quinone) activity
H0N28_18075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H0N28_18145	COG0758	DNA mediated transformation
H0N28_18155	COG0697	spore germination
H0N28_18160	COG1309	transcriptional regulator
H0N28_18175	COG0386	Belongs to the glutathione peroxidase family
H0N28_18245	COG1121	(ABC) transporter
H0N28_18250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H0N28_18255	COG1280	lysine exporter protein (LysE YggA)
H0N28_18260	COG2837	iron assimilation
H0N28_18265	COG0281	malic enzyme
H0N28_18310	COG0519	Catalyzes the synthesis of GMP from XMP
H0N28_18310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0N28_18315	COG4399	Belongs to the UPF0754 family
H0N28_18320	COG2259	Doxx family
H0N28_18325	COG0586	Pfam SNARE associated Golgi protein
H0N28_18340	COG1192	Involved in chromosome partitioning
H0N28_18350	COG0271	Belongs to the BolA IbaG family
H0N28_18390	COG3321	synthase
H0N28_18390	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_18390	COG0300	oxidoreductase activity
H0N28_18390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N28_18390	COG0318	PFAM AMP-dependent synthetase and ligase
H0N28_18395	COG1960	acyl-CoA dehydrogenase activity
H0N28_18400	COG0318	PFAM AMP-dependent synthetase and ligase
H0N28_18405	COG2197	response regulator
H0N28_18415	COG3916	Acyl-homoserine-lactone synthase
H0N28_18420	COG0477	Major facilitator Superfamily
H0N28_18425	COG1024	Enoyl-CoA hydratase
H0N28_18430	COG1024	Enoyl-CoA hydratase
H0N28_18435	COG1960	acyl-CoA dehydrogenase activity
H0N28_18440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0N28_18460	COG1113	amino acid transport
H0N28_18465	COG1113	amino acid transport
H0N28_18470	COG0251	oxidation-reduction process
H0N28_18510	COG0564	pseudouridine synthase activity
H0N28_18590	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H0N28_18605	COG1802	Transcriptional regulator
H0N28_18615	COG1448	Aminotransferase
H0N28_18620	COG0277	FAD linked oxidase domain protein
H0N28_18630	COG2186	Transcriptional regulator
H0N28_18640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0N28_18645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0N28_18660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H0N28_18665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H0N28_18690	COG0438	transferase activity, transferring glycosyl groups
H0N28_18720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H0N28_18750	COG0728	peptidoglycan biosynthetic process
H0N28_18755	COG3023	N-Acetylmuramoyl-L-alanine amidase
H0N28_18815	COG0546	phosphoglycolate phosphatase activity
H0N28_18820	COG1028	Short-chain dehydrogenase reductase Sdr
H0N28_18840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0N28_18845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0N28_18850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0N28_18855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0N28_18860	COG1116	anion transmembrane transporter activity
H0N28_18865	COG1309	transcriptional regulator
H0N28_18870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H0N28_18880	COG0196	riboflavin kinase activity
H0N28_18885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H0N28_18895	COG1047	Peptidyl-prolyl cis-trans
H0N28_18935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0N28_18940	COG0657	acetylesterase activity
H0N28_18990	COG2951	lytic endotransglycosylase activity
H0N28_18995	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H0N28_19010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0N28_19020	COG0671	phosphoesterase, PA-phosphatase related
H0N28_19025	COG0861	Integral membrane protein TerC family
H0N28_19035	COG0754	glutathionylspermidine amidase activity
H0N28_19045	COG0402	S-adenosylhomocysteine deaminase activity
H0N28_19060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0N28_19065	COG1230	cation diffusion facilitator family transporter
H0N28_19080	COG0706	membrane insertase activity
H0N28_19120	COG3077	Addiction module antitoxin, RelB DinJ family
H0N28_19135	COG1028	Short-chain dehydrogenase reductase Sdr