locus-tag	class	description
A1S_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A1S_0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A1S_0006	ENOG4105DQR	SNARE associated Golgi
A1S_0007	ENOG4105C5H	ABC transporter
A1S_0008	ENOG4108821	RND type efflux pump
A1S_0009	ENOG4108821	RND type efflux pump
A1S_0010	ENOG4108821	RND type efflux pump
A1S_0012	ENOG4105D74	hydrolase
A1S_0013	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
A1S_0014	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A1S_0016	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A1S_0018	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A1S_0020	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A1S_0024	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A1S_0025	ENOG4108R86	Transcriptional regulator
A1S_0026	ENOG4108VM9	ABC, transporter
A1S_0027	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A1S_0028	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A1S_0029	ENOG4105GVF	(ABC) transporter
A1S_0030	ENOG4105GVF	(ABC) transporter
A1S_0031	ENOG4107QZM	n-acetylglutamate synthase
A1S_0034	ENOG4105UBK	short-chain dehydrogenase reductase
A1S_0035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A1S_0038	ENOG41062JF	Transcriptional regulator
A1S_0043	ENOG4105HSS	phospholipase C
A1S_0044	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A1S_0045	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
A1S_0046	ENOG4105CJR	Integral membrane protein (MviN
A1S_0047	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A1S_0048	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A1S_0049	ENOG4105D75	Capsular exopolysaccharide family
A1S_0051	ENOG4105DAY	polysaccharide export protein
A1S_0052	ENOG4107QQG	Dehydrogenase
A1S_0053	ENOG4107R5Z	Oxidoreductase domain protein
A1S_0054	ENOG4105J5G	Transferase hexapeptide repeat containing protein
A1S_0055	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A1S_0058	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A1S_0059	ENOG4105CG5	Glycosyl transferase (Group 1
A1S_0060	ENOG4108RYC	glycosyltransferase
A1S_0061	ENOG4105D3Q	Sugar transferase
A1S_0062	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A1S_0063	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A1S_0065	ENOG4105CMR	udp-glucose 4-epimerase
A1S_0066	ENOG4107QKV	phosphomannomutase
A1S_0067	ENOG4105DAA	L-lactate
A1S_0068	ENOG41073TP	transcriptional regulator
A1S_0070	ENOG4105CXG	d-lactate dehydrogenase
A1S_0071	ENOG4105CGF	Aromatic amino acid aminotransferase
A1S_0072	ENOG4105DRR	Transcriptional regulator, GntR family
A1S_0073	ENOG4105CR4	methylisocitrate lyase
A1S_0076	ENOG4108I0Z	Aconitate hydratase
A1S_0089	ENOG4105D3G	Pseudouridine synthase
A1S_0094	ENOG4105EW9	transcriptional regulator AsnC family
A1S_0097	ENOG4105M4H	endoribonuclease L-psp
A1S_0098	ENOG4105C85	amino acid
A1S_0099	ENOG4105C85	amino acid
A1S_0103	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A1S_0105	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_0106	ENOG4105E39	Enoyl-CoA hydratase
A1S_0107	ENOG4105E39	Enoyl-CoA hydratase
A1S_0108	ENOG4105CSH	Transporter
A1S_0112	ENOG4107RCI	amp-dependent synthetase and ligase
A1S_0113	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_0122	ENOG4107PSF	BolA-like protein
A1S_0124	ENOG4107QJE	Chromosome Partitioning Protein
A1S_0127	ENOG4105DQR	SNARE associated Golgi
A1S_0128	ENOG4108VBZ	doxx family
A1S_0129	ENOG4106MP8	UPF0754 membrane protein
A1S_0130	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A1S_0134	ENOG4105EUB	pirin domain protein
A1S_0140	ENOG4107R1I	NAD-dependent malic enzyme
A1S_0141	ENOG4105EZR	dyp-type peroxidase family protein
A1S_0142	ENOG410829K	Lysine exporter protein (Lyse ygga)
A1S_0143	ENOG4105FAV	ABC, transporter
A1S_0144	ENOG4105FDK	ABC transporter
A1S_0150	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A1S_0157	ENOG41090VV	Protein of unknown function (DUF2846)
A1S_0159	ENOG4108V06	Glutathione peroxidase
A1S_0161	ENOG4107RTG	Major Facilitator superfamily
A1S_0162	ENOG4108IND	Tetr family transcriptional regulator
A1S_0166	ENOG4105C79	DNA protecting protein DprA
A1S_0173	ENOG4105Y7M	Transcriptional regulator, TetR family
A1S_0177	ENOG4105C6T	cysteine synthase
A1S_0179	ENOG4105CS1	NAD(P)H quinone oxidoreductase
A1S_0183	ENOG4105CCT	upf0313 protein
A1S_0186	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A1S_0188	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A1S_0189	ENOG4108URH	decarboxylase
A1S_0190	ENOG4105EE5	Membrane protein terC
A1S_0191	ENOG4105K5B	UPF0225 protein
A1S_0192	ENOG4105EN6	Membrane
A1S_0193	ENOG41079KZ	Major Facilitator Superfamily
A1S_0200	ENOG4105F0N	pyrophosphate phospho-hydrolase
A1S_0201	ENOG41090KI	Outer membrane porin
A1S_0203	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A1S_0205	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A1S_0215	ENOG4105CHH	sulfate transporter
A1S_0219	ENOG4105BZU	Histidine kinase
A1S_0221	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A1S_0229	ENOG4108K5H	permease YjgP YjgQ family protein
A1S_0230	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A1S_0231	ENOG4105CN1	protease
A1S_0232	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A1S_0233	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A1S_0234	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A1S_0235	ENOG4107TUY	Histidine kinase
A1S_0237	ENOG41061WM	D-Alanyl-D-Alanine
A1S_0239	ENOG4105D6E	homoserine dehydrogenase
A1S_0240	ENOG4105T95	Thiol disulfide interChange protein
A1S_0241	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A1S_0243	ENOG4105CE1	Ferrous iron transport protein b
A1S_0246	ENOG4105CNI	cell division protein FtsW
A1S_0247	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
A1S_0248	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A1S_0249	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A1S_0254	ENOG4108RNG	Permease of the drug metabolite transporter
A1S_0255	ENOG4105DFG	type I secretion outer membrane protein
A1S_0256	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A1S_0260	ENOG4108HRK	Histidine kinase
A1S_0261	ENOG4108NEV	two component transcriptional regulator, LytTR family
A1S_0262	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A1S_0268	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
A1S_0271	ENOG4105GVR	general secretion pathway protein D
A1S_0272	ENOG4105TV9	FHA Domain-Containing protein
A1S_0273	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A1S_0281	ENOG4105PM1	preprotein translocase subunit SecE
A1S_0282	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A1S_0290	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A1S_0291	ENOG4105D3Y	Na H antiporter
A1S_0298	ENOG4107ZXU	DSBA oxidoreductase
A1S_0312	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A1S_0319	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A1S_0321	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A1S_0324	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A1S_0326	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A1S_0329	ENOG4107QHF	type ii secretion system protein e
A1S_0331	ENOG4107EJC	Preprotein translocase subunit SecG
A1S_0335	ENOG4105CHV	Transcription elongation factor NusA
A1S_0339	ENOG4105KJM	monovalent cation h antiporter subunit g
A1S_0340	ENOG4105SC1	monovalent cation H antiporter subunit E
A1S_0341	ENOG4107R4Z	monovalent cation h antiporter subunit d
A1S_0342	ENOG4108ZE9	Monovalent cation H antiporter subunit C
A1S_0343	ENOG4105D65	subunit l
A1S_0346	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A1S_0350	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A1S_0352	ENOG4105CSR	polyphosphate kinase 2
A1S_0354	ENOG4105DSY	exodeoxyribonuclease V, gamma
A1S_0357	ENOG4107QKA	exodeoxyribonuclease V beta
A1S_0358	ENOG4107QYX	exodeoxyribonuclease v alpha
A1S_0362	ENOG4107QUT	magnesium and cobalt transport protein CorA
A1S_0363	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
A1S_0364	ENOG4105DVC	DnaJ domain protein
A1S_0367	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A1S_0368	ENOG4105C25	Primosomal protein n'
A1S_0369	ENOG4105D7Q	type ii secretion system
A1S_0370	ENOG4108VAU	general secretion pathway protein G
A1S_0372	ENOG4108Z7R	Chaperone CsaA
A1S_0373	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A1S_0375	ENOG4108JU5	Magnesium and cobalt efflux protein
A1S_0376	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A1S_0378	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A1S_0380	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A1S_0383	ENOG4105C5X	domain protein
A1S_0385	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
A1S_0387	ENOG4105BZ8	glutamate synthase
A1S_0393	ENOG4107T8P	acyl-Coa dehydrogenase
A1S_0395	ENOG4107QI1	Mate efflux family protein
A1S_0397	ENOG4105CSA	Coproporphyrinogen iii oxidase
A1S_0399	ENOG4105CBN	LysR family transcriptional regulator
A1S_0403	ENOG4105C03	ribonuclease
A1S_0406	ENOG4107XGZ	Hydrolase
A1S_0407	ENOG4105D29	Helix-turn-helix type 11 domain protein
A1S_0410	ENOG4108W5M	transcriptional regulator
A1S_0413	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
A1S_0416	ENOG4105DUM	transcriptional regulator, lysR family
A1S_0420	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A1S_0429	ENOG4105CK2	sodium dicarboxylate symporter
A1S_0431	ENOG4105D1S	lipid A biosynthesis
A1S_0432	ENOG4105N14	lysine exporter protein LysE YggA
A1S_0433	ENOG4105C5H	ABC transporter
A1S_0434	ENOG41069P5	Protein slyX homolog
A1S_0437	ENOG4105KVH	Transcriptional regulator
A1S_0439	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A1S_0442	ENOG4105C4R	Atp-dependent dna helicase
A1S_0443	ENOG4105VFU	Rna-binding protein
A1S_0446	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A1S_0447	ENOG4105W0E	50S ribosomal protein L33
A1S_0448	ENOG4105KDC	50s ribosomal protein l28
A1S_0449	ENOG4107RGH	Aldehyde dehydrogenase
A1S_0451	ENOG4105CIY	formyltetrahydrofolate deformylase
A1S_0470	ENOG4105DWV	Homoserine O-trans-acetylase
A1S_0472	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A1S_0474	ENOG4108ESX	Receptor
A1S_0476	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A1S_0480	ENOG4107GFK	fumarate
A1S_0481	ENOG4108DNC	Involved in acetate metabolism (By similarity)
A1S_0482	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A1S_0483	ENOG4105C01	Dihydroxy-acid dehydratase
A1S_0484	ENOG4108UHU	Aldolase
A1S_0486	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A1S_0490	ENOG4106HB6	Alpha beta hydrolase
A1S_0493	ENOG4105CN1	protease
A1S_0494	ENOG4105BZF	Glycosyl transferase (Group 1
A1S_0497	ENOG4105WVQ	Fe-S assembly protein IscX
A1S_0501	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
A1S_0505	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A1S_0512	ENOG4105CEY	Amp-dependent synthetase and ligase
A1S_0513	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A1S_0515	ENOG4105C84	Histidine ammonia-lyase
A1S_0522	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A1S_0524	ENOG4105C2D	reductase
A1S_0525	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A1S_0529	ENOG4105VW4	glutaredoxin 3
A1S_0531	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A1S_0532	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A1S_0534	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A1S_0535	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A1S_0536	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A1S_0538	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A1S_0543	ENOG4105C7K	acetolactate synthase
A1S_0544	ENOG4108ZP8	Acetolactate synthase small subunit
A1S_0546	ENOG4105BZU	Histidine kinase
A1S_0554	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A1S_0557	ENOG4105F8V	Hydrolase, tatD family
A1S_0558	ENOG4107QM5	aconitate hydratase
A1S_0559	ENOG4105CUZ	uba thif-type nad fad binding protein
A1S_0560	ENOG4107RSM	transcriptional regulator
A1S_0562	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A1S_0565	ENOG4106UX7	integral membrane protein
A1S_0566	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A1S_0567	ENOG4105W8H	transhydrogenase (subunit alpha
A1S_0568	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A1S_0571	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
A1S_0572	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A1S_0573	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
A1S_0574	ENOG4105BZU	Histidine kinase
A1S_0575	ENOG4105C6T	cysteine synthase
A1S_0579	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A1S_0581	ENOG4105DXN	mazG family
A1S_0582	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
A1S_0583	ENOG4105DJ0	Poly(A) Polymerase
A1S_0584	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A1S_0589	ENOG41080Z8	PHOSPHOCARRIER protein
A1S_0590	ENOG4105N42	UPF0307 protein
A1S_0591	ENOG4105CEY	Amp-dependent synthetase and ligase
A1S_0594	ENOG4105CYM	Glutathione S-transferase
A1S_0595	ENOG4105W39	Membrane
A1S_0597	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A1S_0602	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A1S_0607	ENOG4105C9X	ppx gppa phosphatase
A1S_0609	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A1S_0610	ENOG4105II7	pyrroline-5-carboxylate reductase
A1S_0611	ENOG4108VIA	integral membrane protein
A1S_0612	ENOG4105C2M	dna polymerase I
A1S_0616	ENOG4107QHF	type ii secretion system protein e
A1S_0617	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A1S_0618	ENOG4105K56	Transcriptional regulator
A1S_0624	ENOG4108K0D	peptidase, M48
A1S_0634	ENOG4105DR5	peptidase
A1S_0636	ENOG4105KT5	UmuD protein
A1S_0637	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A1S_0639	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
A1S_0643	ENOG4107QHF	type ii secretion system protein e
A1S_0648	ENOG4105KK6	nuclease
A1S_0653	ENOG4105CE1	Ferrous iron transport protein b
A1S_0657	ENOG4105MP0	transposase
A1S_0669	ENOG4105D6J	arsenicaL-resistance protein
A1S_0685	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A1S_0686	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A1S_0687	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A1S_0689	ENOG4105CRQ	synthase (Component I)
A1S_0698	ENOG4108Z0R	Transferase
A1S_0699	ENOG41072GX	Peptidase M22 Glycoprotease
A1S_0705	ENOG4105DJV	ribulose-phosphate 3-epimerase
A1S_0706	ENOG4108HCJ	Hydrolase
A1S_0707	ENOG4105E3B	Multicopper oxidase
A1S_0711	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A1S_0712	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
A1S_0713	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A1S_0720	ENOG4105ETT	transcriptional Regulator, LysR family
A1S_0721	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_0722	ENOG4107RGD	Major Facilitator superfamily
A1S_0723	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A1S_0725	ENOG4107EFR	Flavocytochrome c
A1S_0726	ENOG4106P55	Transcriptional regulator
A1S_0729	ENOG4106P55	Transcriptional regulator
A1S_0731	ENOG4105CH2	amidohydrolase
A1S_0735	ENOG4105ETT	transcriptional Regulator, LysR family
A1S_0737	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A1S_0738	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
A1S_0746	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A1S_0747	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A1S_0748	ENOG4107EXC	regulatoR
A1S_0749	ENOG4105E0F	Histidine kinase
A1S_0751	ENOG4105BZU	Histidine kinase
A1S_0755	ENOG4105GKE	subunit e
A1S_0756	ENOG4107QIZ	NADH dehydrogenase
A1S_0757	ENOG4108IEH	NADH dehydrogenase subunit g
A1S_0760	ENOG4107UFS	subunit j
A1S_0762	ENOG4105D65	subunit l
A1S_0763	ENOG4105C8S	subunit m
A1S_0768	ENOG4105DUM	transcriptional regulator, lysR family
A1S_0769	ENOG4105DP0	ferredoxin-NADP reductase
A1S_0772	ENOG4105CBX	hi0933 family
A1S_0773	ENOG4105K6H	D-cysteine desulfhydrase
A1S_0778	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A1S_0780	ENOG4105D1F	ATP-binding protein
A1S_0789	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A1S_0795	ENOG4105HF0	Membrane
A1S_0797	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A1S_0801	ENOG4106UW1	Major Facilitator superfamily
A1S_0803	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
A1S_0804	ENOG4108K4C	ec 3.1.3.12
A1S_0805	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A1S_0807	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A1S_0808	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A1S_0810	ENOG4105FE9	pseudouridine synthase
A1S_0811	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A1S_0812	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A1S_0813	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A1S_0814	ENOG4108BPE	-transporting atpase
A1S_0815	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
A1S_0817	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A1S_0818	ENOG4105CHR	reductase
A1S_0820	ENOG4109066	lysm domain bon superfamily protein
A1S_0821	ENOG4105DWF	phosphomethylpyrimidine kinase
A1S_0823	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A1S_0829	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A1S_0835	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
A1S_0838	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A1S_0839	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A1S_0840	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1S_0841	ENOG4105C34	Pseudouridine synthase
A1S_0842	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A1S_0848	ENOG4105EJC	lysr family transcriptional regulator
A1S_0849	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A1S_0850	ENOG4105C94	Transporter
A1S_0852	ENOG4105DVW	rieske (2Fe-2S)
A1S_0853	ENOG4105C26	Dehydrogenase
A1S_0854	ENOG4105C26	Dehydrogenase
A1S_0855	ENOG4105E3J	oxidoreductase
A1S_0858	ENOG4105C4K	Nad synthetase
A1S_0861	ENOG4105EUB	pirin domain protein
A1S_0862	ENOG4108YXA	Membrane
A1S_0863	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A1S_0872	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A1S_0874	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A1S_0875	ENOG4105C3M	thioredoxin reductase
A1S_0876	ENOG4105CNU	cell division protein FtsK
A1S_0880	ENOG4107QMS	site-determining protein
A1S_0883	ENOG4106HNH	Acyl-transferase
A1S_0884	ENOG4108ZG0	Ompa motb domain protein
A1S_0885	ENOG4105C4R	Atp-dependent dna helicase
A1S_0887	ENOG4107QKV	phosphomannomutase
A1S_0890	ENOG4105E7A	Glutamine amidotransferase
A1S_0893	ENOG4105VDB	UPF0125 protein
A1S_0895	ENOG41090R7	Ferric uptake
A1S_0896	ENOG4105CZX	twitching motility protein
A1S_0897	ENOG4105CZX	twitching motility protein
A1S_0898	ENOG4105DFA	alanine racemase domain protein
A1S_0899	ENOG4105EYH	Exonuclease
A1S_0900	ENOG4107RH8	nuclease SbcCD subunit D
A1S_0904	ENOG4105ECP	epimerase
A1S_0905	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A1S_0906	ENOG4105D52	delta-aminolevulinic acid dehydratase
A1S_0907	ENOG4108VUY	thioesterase Superfamily protein
A1S_0908	ENOG4105CW7	secretion protein, HlyD family
A1S_0909	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A1S_0910	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A1S_0915	ENOG4105C54	Major Facilitator superfamily
A1S_0916	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A1S_0921	ENOG4105D5Q	Arginine ornithine antiporter
A1S_0922	ENOG4107QK5	Homocysteine s-methyltransferase
A1S_0928	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
A1S_0929	ENOG4105C94	Transporter
A1S_0930	ENOG4105C94	Transporter
A1S_0931	ENOG4105C94	Transporter
A1S_0934	ENOG4105CKI	cobalamin synthesis protein
A1S_0936	ENOG4108VWS	Yaeq family
A1S_0938	ENOG4107BJW	polysaccharide deacetylase
A1S_0939	ENOG4105CND	Glycosyl transferase, family 2
A1S_0941	ENOG4106YT9	Enoyl-CoA hydratase
A1S_0944	ENOG41069M3	Transcriptional regulator
A1S_0948	ENOG4105CHR	reductase
A1S_0950	ENOG4107QZF	nitrite reductase NADPH large subunit
A1S_0952	ENOG4105DJB	Major Facilitator Superfamily
A1S_0954	ENOG4108MXF	Alpha Beta Hydrolase
A1S_0955	ENOG4105CHR	reductase
A1S_0958	ENOG4105C7K	acetolactate synthase
A1S_0960	ENOG4105CSH	Transporter
A1S_0961	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A1S_0962	ENOG4105CSV	Glutaminase
A1S_0963	ENOG4108R6W	Transcriptional regulator, ARAC family
A1S_0964	ENOG4105EU0	Major facilitator Superfamily
A1S_0965	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A1S_0966	ENOG4108PZW	LysR family Transcriptional regulator
A1S_0968	ENOG4105CSP	Major Facilitator Superfamily
A1S_0971	ENOG4105C3R	Methionine synthase
A1S_0972	ENOG4105CJ3	phosphate transporter
A1S_0976	ENOG4105E6M	Sulphatase-modifying factor protein
A1S_0977	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
A1S_0980	ENOG4107RNH	Outer membrane receptor FepA
A1S_0981	ENOG4107RNH	Outer membrane receptor FepA
A1S_0985	ENOG4108UJV	acyl-CoA thioesterase i
A1S_0986	ENOG4108I0Y	(ABC) transporter
A1S_0987	ENOG4105CV6	ABC transporter, permease
A1S_0988	ENOG4107U91	Rhomboid family
A1S_0992	ENOG4105C5Q	Transcriptional regulator
A1S_0994	ENOG4107QZF	nitrite reductase NADPH large subunit
A1S_0995	ENOG4105VCQ	rubredoxin
A1S_0999	ENOG4108MRJ	
A1S_1001	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
A1S_1004	ENOG4105D4T	Citrate transporter
A1S_1005	ENOG4105C37	(CBS) domain
A1S_1006	ENOG41064T2	transcriptional regulator, lysR family
A1S_1008	ENOG4107RET	Isocitrate lyase
A1S_1014	ENOG4105CQM	Urea amidohydrolase subunit alpha
A1S_1016	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
A1S_1019	ENOG4106H78	methyltransferase
A1S_1020	ENOG4105CJN	penicillin-binding protein
A1S_1024	ENOG4105CSM	endonuclease III
A1S_1025	ENOG4108R3D	Electron transport complex
A1S_1026	ENOG4105D82	Glutamate dehydrogenase
A1S_1028	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
A1S_1034	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A1S_1039	ENOG4107RAQ	aminopeptidase
A1S_1040	ENOG4105D0A	hydroxylase
A1S_1041	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A1S_1046	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A1S_1047	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
A1S_1048	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A1S_1050	ENOG4105W4M	Transport-associated protein
A1S_1052	ENOG4105E09	nadh pyrophosphatase
A1S_1054	ENOG4107RZZ	dna polymerase iii epsilon subunit
A1S_1055	ENOG4105E9H	Lytic Murein transglycosylase
A1S_1055	ENOG4105E9H	Lytic Murein transglycosylase
A1S_1057	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
A1S_1058	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
A1S_1060	ENOG4108JQ5	ABC transporter
A1S_1061	ENOG4108JQ5	ABC transporter
A1S_1065	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A1S_1070	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A1S_1074	ENOG4105M4H	endoribonuclease L-psp
A1S_1075	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A1S_1076	ENOG4105CR8	Transcriptional regulator
A1S_1080	ENOG4105D01	(LipO)protein
A1S_1083	ENOG4105C85	amino acid
A1S_1085	ENOG4105CUB	amino acid
A1S_1089	ENOG4105C26	Dehydrogenase
A1S_1092	ENOG4105C8Y	Acetylornithine aminotransferase
A1S_1094	ENOG4105C85	amino acid
A1S_1095	ENOG4107RGH	Aldehyde dehydrogenase
A1S_1096	ENOG4108ZX5	transcriptional regulator
A1S_1097	ENOG4105DJP	Membrane
A1S_1098	ENOG4105CTX	dehydratase
A1S_1099	ENOG4105DJB	Major Facilitator Superfamily
A1S_1100	ENOG4105EQX	glucarate dehydratase
A1S_1102	ENOG4105CZJ	Aldehyde dehydrogenase
A1S_1103	ENOG4105JXH	GntR family transcriptional regulator
A1S_1106	ENOG4105NI3	Protein of unknown function (DUF3237)
A1S_1107	ENOG4105EPF	Outer membrane porin
A1S_1108	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_1111	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
A1S_1112	ENOG4108SC4	)-transporter
A1S_1115	ENOG4105E3J	oxidoreductase
A1S_1117	ENOG4105D2S	major facilitator superfamily
A1S_1118	ENOG4105EPF	Outer membrane porin
A1S_1123	ENOG4107RN6	Monooxygenase
A1S_1125	ENOG4105JQZ	Methyltransferase
A1S_1126	ENOG4105F95	Monooxygenase
A1S_1133	ENOG4105F95	Monooxygenase
A1S_1134	ENOG4107RN6	Monooxygenase
A1S_1136	ENOG4105C7N	Xanthine uracil vitamin C permease
A1S_1137	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A1S_1138	ENOG4105CPW	cytochrome b561
A1S_1140	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A1S_1142	ENOG4105CFH	Aspartokinase
A1S_1144	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A1S_1145	ENOG4105W7J	DNA binding
A1S_1153	ENOG4107ZQ5	Phage-associated protein, HI1409 family
A1S_1155	ENOG41090AG	Bacteriophage protein
A1S_1175	ENOG4105DFP	Integrase
A1S_1177	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A1S_1179	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A1S_1181	ENOG4105CPC	Aldo Keto reductase
A1S_1182	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
A1S_1183	ENOG4108UKZ	OsmC family
A1S_1186	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A1S_1191	ENOG4105CD3	dihydroorotase
A1S_1193	ENOG4108ZG0	Ompa motb domain protein
A1S_1195	ENOG4108TGY	Glutathione S-transferase
A1S_1196	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A1S_1199	ENOG4108K3A	Glutathione S-transferase
A1S_1200	ENOG4108JU3	Alkyl hydroperoxide reductase
A1S_1201	ENOG4108JU3	Alkyl hydroperoxide reductase
A1S_1203	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A1S_1205	ENOG4105D3R	alkyl hydroperoxide reductase
A1S_1206	ENOG4105CQ7	ATP-dependent helicase
A1S_1210	ENOG4105D2S	major facilitator superfamily
A1S_1211	ENOG4105DKK	Benzoate
A1S_1212	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
A1S_1213	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
A1S_1214	ENOG4108UKV	benzoate 1,2-dioxygenase
A1S_1215	ENOG4105FUY	alpha subunit
A1S_1216	ENOG4108KB2	LysR family Transcriptional regulator
A1S_1222	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A1S_1227	ENOG410829K	Lysine exporter protein (Lyse ygga)
A1S_1228	ENOG4105VEQ	Cold shock protein
A1S_1229	ENOG4105II7	pyrroline-5-carboxylate reductase
A1S_1232	ENOG4107YPT	transcriptional regulator
A1S_1236	ENOG4105C2X	Arabinose 5-phosphate isomerase
A1S_1237	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
A1S_1239	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
A1S_1240	ENOG4108IUZ	ABC transporter
A1S_1241	ENOG4105DFG	type I secretion outer membrane protein
A1S_1249	ENOG4108Z4U	Ferredoxin
A1S_1253	ENOG4107AQZ	Membrane
A1S_1254	ENOG4105BZU	Histidine kinase
A1S_1255	ENOG4105D1S	lipid A biosynthesis
A1S_1257	ENOG4105D2S	major facilitator superfamily
A1S_1261	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
A1S_1263	ENOG4105PAD	Hydrolase
A1S_1265	ENOG4108WAV	Transcriptional regulator
A1S_1266	ENOG4105C5A	transporter
A1S_1270	ENOG4108JIK	carboxylase
A1S_1271	ENOG4107R4J	Chloride channel
A1S_1272	ENOG4105R8C	Transcriptional regulator
A1S_1274	ENOG4105E2A	Dehydrogenase
A1S_1277	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A1S_1278	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
A1S_1279	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
A1S_1282	ENOG4105MRR	Transcriptional regulator (By similarity)
A1S_1284	ENOG4108HW3	(ABC) transporter
A1S_1291	ENOG4105E6M	Sulphatase-modifying factor protein
A1S_1305	ENOG4105UYK	outer membrane protein a
A1S_1307	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A1S_1313	ENOG4105EMY	transcriptional regulator
A1S_1315	ENOG4107Y2X	deaminase
A1S_1316	ENOG4105DJ2	Major Facilitator Superfamily
A1S_1319	ENOG4105WPN	DNA integration recombination invertion protein
A1S_1320	ENOG4108Z4X	TRANSCRIPTIONal
A1S_1322	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A1S_1326	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A1S_1332	ENOG4105CZJ	Aldehyde dehydrogenase
A1S_1333	ENOG4107QTZ	amino acid
A1S_1334	ENOG4105EJQ	L-serine dehydratase
A1S_1335	ENOG4105DXM	phenylacetic acid degradation protein
A1S_1336	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
A1S_1337	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
A1S_1338	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
A1S_1339	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
A1S_1340	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A1S_1341	ENOG4105E39	Enoyl-CoA hydratase
A1S_1342	ENOG4108UKI	Enoyl-CoA hydratase
A1S_1343	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A1S_1344	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_1345	ENOG4105DZS	Phenylacetate-CoA ligase
A1S_1346	ENOG4105DZS	Phenylacetate-CoA ligase
A1S_1347	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
A1S_1348	ENOG4108Z0R	Transferase
A1S_1349	ENOG4107YAU	phenylacetic acid degradation protein
A1S_1351	ENOG4107VGR	Catalase
A1S_1352	ENOG4105CPW	cytochrome b561
A1S_1353	ENOG4105HEI	LysR family (Transcriptional regulator
A1S_1355	ENOG4107HP6	Transcriptional regulator
A1S_1356	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
A1S_1359	ENOG4105C4Y	ABC transporter
A1S_1360	ENOG4108IJ6	ABC transporter
A1S_1361	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A1S_1362	ENOG4107RCV	ABC transporter, permease
A1S_1364	ENOG4107STF	Involved in phosphonate degradation (By similarity)
A1S_1365	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
A1S_1366	ENOG4108NIW	Leucine export protein LeuE
A1S_1371	ENOG4105CC0	LysR family Transcriptional regulator
A1S_1374	ENOG4105E39	Enoyl-CoA hydratase
A1S_1375	ENOG4107QX3	carboxylase
A1S_1376	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_1377	ENOG4105R8C	Transcriptional regulator
A1S_1378	ENOG4105CEY	Amp-dependent synthetase and ligase
A1S_1382	ENOG4105HEI	LysR family (Transcriptional regulator
A1S_1387	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A1S_1391	ENOG4105EW9	transcriptional regulator AsnC family
A1S_1393	ENOG4105BZU	Histidine kinase
A1S_1394	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A1S_1396	ENOG4105E5Q	amino acid AbC transporter
A1S_1397	ENOG4108HW4	amino acid AbC transporter
A1S_1399	ENOG4107RP9	extracellular solute-binding protein, family 3
A1S_1400	ENOG4105CT1	(ABC) transporter
A1S_1401	ENOG4105EXG	Transcriptional regulator
A1S_1403	ENOG4105C9B	Cysteine desulfurase
A1S_1404	ENOG4105C9B	Cysteine desulfurase
A1S_1405	ENOG4105C9B	Cysteine desulfurase
A1S_1406	ENOG4105ESN	nucleotide-binding protein
A1S_1407	ENOG4105D7W	serine acetyltransferase
A1S_1409	ENOG4105CHR	reductase
A1S_1410	ENOG4105CBN	LysR family transcriptional regulator
A1S_1411	ENOG4105CYM	Glutathione S-transferase
A1S_1412	ENOG4108SHQ	Glutathione S-transferase
A1S_1413	ENOG4105CMU	LysR family (Transcriptional regulator
A1S_1414	ENOG41067MG	lrgb family
A1S_1415	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A1S_1418	ENOG4105DXI	Major Facilitator superfamily
A1S_1420	ENOG4105ETT	transcriptional Regulator, LysR family
A1S_1422	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
A1S_1423	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
A1S_1426	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
A1S_1427	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A1S_1430	ENOG4108K70	Transcriptional regulator
A1S_1431	ENOG4108K70	Transcriptional regulator
A1S_1432	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A1S_1433	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A1S_1434	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A1S_1440	ENOG4105C54	Major Facilitator superfamily
A1S_1442	ENOG4106FTQ	Taurine ABC transporter, periplasmic
A1S_1443	ENOG4108IY8	ABC, transporter
A1S_1444	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A1S_1445	ENOG4105E2B	Taurine dioxygenase
A1S_1447	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A1S_1449	ENOG4105CBN	LysR family transcriptional regulator
A1S_1451	ENOG4105CPN	adenine deaminase
A1S_1453	ENOG41082YX	Transcriptional regulator, arsr family
A1S_1454	ENOG4105D6J	arsenicaL-resistance protein
A1S_1455	ENOG4108KB2	LysR family Transcriptional regulator
A1S_1458	ENOG4108JU3	Alkyl hydroperoxide reductase
A1S_1460	ENOG4108JU3	Alkyl hydroperoxide reductase
A1S_1465	ENOG4105C0B	DNA polymerase III (alpha subunit)
A1S_1468	ENOG4105CHM	Aminotransferase
A1S_1470	ENOG4108V06	Glutathione peroxidase
A1S_1471	ENOG4105E7U	AraC family transcriptional regulator
A1S_1477	ENOG4108UMN	azlc family
A1S_1481	ENOG4105C3G	gtp-binding protein
A1S_1482	ENOG4108UMI	ABC transporter, permease
A1S_1483	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A1S_1484	ENOG4105D01	(LipO)protein
A1S_1485	ENOG4105D01	(LipO)protein
A1S_1488	ENOG4107T8P	acyl-Coa dehydrogenase
A1S_1491	ENOG4105EAD	ABC transporter
A1S_1492	ENOG4105DRP	amino acid AbC transporter
A1S_1493	ENOG4105CDA	abc transporter atp-binding protein
A1S_1495	ENOG4105EW9	transcriptional regulator AsnC family
A1S_1498	ENOG41067SE	Tetr family transcriptional regulator
A1S_1502	ENOG4105CC0	LysR family Transcriptional regulator
A1S_1504	ENOG4105ETS	cytosine purines uracil thiamine allantoin
A1S_1505	ENOG4108IPJ	Membrane
A1S_1509	ENOG4105GQR	Chaperone
A1S_1510	ENOG4105X0I	Fimbrial
A1S_1512	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A1S_1513	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A1S_1516	ENOG4108Z7F	N-acetyltransferase
A1S_1517	ENOG4108HWY	Beta-lactamase
A1S_1520	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A1S_1521	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A1S_1523	ENOG4108YYC	ycei family
A1S_1525	ENOG4108T58	Mg2 transport protein CorA
A1S_1528	ENOG4105C26	Dehydrogenase
A1S_1529	ENOG4105EW9	transcriptional regulator AsnC family
A1S_1530	ENOG4105CK7	Sodium proline symporter
A1S_1531	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A1S_1533	ENOG4108ZX5	transcriptional regulator
A1S_1535	ENOG4105BZ1	(ABC) transporter
A1S_1536	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
A1S_1537	ENOG4105XPP	Protein of unknown function (DUF1275)
A1S_1539	ENOG41080HT	Transcriptional regulator, arsr family
A1S_1541	ENOG4105EZE	Cupin 4 family protein
A1S_1542	ENOG4108UHJ	MAF-like protein
A1S_1544	ENOG4105D2N	Aldolase
A1S_1545	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A1S_1546	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A1S_1547	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A1S_1548	ENOG4105EHM	Aminoglycoside phosphotransferase
A1S_1549	ENOG4108S0S	Nucleotidyl transferase
A1S_1551	ENOG4107QJE	Chromosome Partitioning Protein
A1S_1552	ENOG4105FA0	parb-like partition protein
A1S_1555	ENOG4105BZ1	(ABC) transporter
A1S_1556	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A1S_1558	ENOG4107QRG	dna polymerase iii
A1S_1560	ENOG4105F8V	Hydrolase, tatD family
A1S_1565	ENOG4108RTD	type II secretion system protein K
A1S_1569	ENOG4108Z6B	deaminase
A1S_1572	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A1S_1573	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A1S_1577	ENOG4107RN6	Monooxygenase
A1S_1579	ENOG4105D6Z	AFG1 family ATPase
A1S_1580	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A1S_1585	ENOG4105CDU	Replicative dna helicase
A1S_1589	ENOG4105EFC	phage portal protein HK97 family
A1S_1601	ENOG4107QP3	malate synthase g
A1S_1603	ENOG4105SG9	biopolymer transport protein, ExbD
A1S_1610	ENOG4105DGW	oligopeptidase A
A1S_1612	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A1S_1615	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A1S_1618	ENOG4105K4T	epimerase
A1S_1619	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A1S_1623	ENOG4108JA2	transcriptioN-repair coupling factor
A1S_1627	ENOG4108ZIT	Ferredoxin, 2FE-2S
A1S_1630	ENOG4108Z4V	iron-sulfur cluster assembly
A1S_1631	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
A1S_1634	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
A1S_1637	ENOG4105K70	DNA-binding protein
A1S_1638	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A1S_1640	ENOG4105E7U	AraC family transcriptional regulator
A1S_1641	ENOG4105EEF	Alkane 1-monooxygenase
A1S_1642	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_1643	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_1646	ENOG4108Z66	YbaK ebsC protein
A1S_1649	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A1S_1650	ENOG4105DUU	IucA IucC family protein
A1S_1651	ENOG4105DUU	IucA IucC family protein
A1S_1652	ENOG4105DJU	Siderophore biosynthesis protein
A1S_1654	ENOG4105JSC	dimethylmenaquinone methyltransferase
A1S_1658	ENOG4107VXZ	Hydrolase
A1S_1659	ENOG4108YZT	Adenosylcobinamide kinase
A1S_1660	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
A1S_1661	ENOG4107TB6	phosphoglycerate mutase
A1S_1664	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A1S_1665	ENOG4107TSN	permease
A1S_1667	ENOG4105CNM	Receptor
A1S_1668	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A1S_1671	ENOG4105CJ1	ABC, transporter
A1S_1672	ENOG4107QWP	ABC-2 type transporter
A1S_1673	ENOG4107QWP	ABC-2 type transporter
A1S_1678	ENOG4105K59	histidine triad (HIT) protein
A1S_1681	ENOG4105F2W	methyltransferase
A1S_1683	ENOG4105C28	cystathionine
A1S_1685	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A1S_1686	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A1S_1690	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A1S_1692	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A1S_1693	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
A1S_1695	ENOG4105BZU	Histidine kinase
A1S_1698	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A1S_1699	ENOG4107R0V	Pyruvate dehydrogenase
A1S_1700	ENOG4105CPP	Dehydrogenase, E1 component
A1S_1702	ENOG4107QN2	dihydrolipoyl dehydrogenase
A1S_1704	ENOG4105CHR	reductase
A1S_1706	ENOG4105FFC	UPF0187 protein
A1S_1708	ENOG4107S76	domain protein
A1S_1710	ENOG4108VCT	Sulfite exporter TauE/SafE
A1S_1713	ENOG4105UEI	Transcriptional Regulator AraC Family
A1S_1714	ENOG4105KVH	Transcriptional regulator
A1S_1715	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A1S_1717	ENOG4105FDP	GntR family transcriptional regulator
A1S_1720	ENOG4106FTQ	Taurine ABC transporter, periplasmic
A1S_1721	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A1S_1724	ENOG4105CSH	Transporter
A1S_1726	ENOG4108IJ0	Aspartate ammonia-lyase
A1S_1727	ENOG4107YNJ	LysR family Transcriptional regulator
A1S_1729	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_1730	ENOG4105CRW	Short chain fatty acid transporter
A1S_1733	ENOG4108M0I	Transcriptional regulator
A1S_1736	ENOG4105CY2	Citrate transporter
A1S_1737	ENOG4105DTD	Dehydrogenase
A1S_1738	ENOG4105CF7	AraC family transcriptional regulator
A1S_1739	ENOG4105D2S	major facilitator superfamily
A1S_1740	ENOG4105D2S	major facilitator superfamily
A1S_1742	ENOG4105CHR	reductase
A1S_1747	ENOG4105F57	Anthranilate dioxygenase reductase
A1S_1750	ENOG4105BZS	acriflavin resistance protein
A1S_1751	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A1S_1752	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A1S_1753	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A1S_1754	ENOG4105E0F	Histidine kinase
A1S_1755	ENOG4108821	RND type efflux pump
A1S_1756	ENOG4108R6W	Transcriptional regulator, ARAC family
A1S_1762	ENOG4105M03	Domain of unknown function (DUF955)
A1S_1767	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A1S_1781	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A1S_1785	ENOG4105E0A	ABC, transporter
A1S_1786	ENOG4105EHG	Permease protein
A1S_1788	ENOG4105DQ4	alcohol dehydrogenase
A1S_1789	ENOG4105CF7	AraC family transcriptional regulator
A1S_1790	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A1S_1792	ENOG4105EXW	epimerase dehydratase
A1S_1793	ENOG4105DDW	LysR family Transcriptional regulator
A1S_1795	ENOG4105C01	Dihydroxy-acid dehydratase
A1S_1796	ENOG4105CZJ	Aldehyde dehydrogenase
A1S_1797	ENOG4105CZJ	Aldehyde dehydrogenase
A1S_1800	ENOG4105CW7	secretion protein, HlyD family
A1S_1801	ENOG4105CW7	secretion protein, HlyD family
A1S_1804	ENOG4106KR7	LysR family Transcriptional regulator
A1S_1807	ENOG4105FDP	GntR family transcriptional regulator
A1S_1815	ENOG4105CEY	Amp-dependent synthetase and ligase
A1S_1817	ENOG4105CSU	acyl-Coa dehydrogenase
A1S_1819	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
A1S_1820	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A1S_1821	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A1S_1822	ENOG4108PTX	LysR family Transcriptional regulator
A1S_1823	ENOG4107Z3H	Transcriptional regulator, TetR family
A1S_1828	ENOG4108Z6Z	Transcriptional regulator
A1S_1830	ENOG4105NAE	bifunctional deaminase-reductase domain protein
A1S_1832	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A1S_1835	ENOG4105CZJ	Aldehyde dehydrogenase
A1S_1840	ENOG4107EJG	GntR family transcriptional regulator
A1S_1842	ENOG4108KB2	LysR family Transcriptional regulator
A1S_1843	ENOG4105DTQ	mandelate racemase muconate lactonizing
A1S_1844	ENOG4105NN7	muconolactone delta-isomerase
A1S_1846	ENOG4107QP7	CoA-transferase subunit A
A1S_1847	ENOG4107QNJ	CoA-transferase subunit B
A1S_1848	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_1849	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_1850	ENOG4105F2Z	3-oxoadipate enol-lactonase
A1S_1852	ENOG4105C26	Dehydrogenase
A1S_1854	ENOG4105F11	amine oxidase
A1S_1858	ENOG4105CHR	reductase
A1S_1861	ENOG4105FUY	alpha subunit
A1S_1865	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A1S_1867	ENOG4105DNH	Major Facilitator
A1S_1873	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_1874	ENOG4108PTX	LysR family Transcriptional regulator
A1S_1875	ENOG4107HP6	Transcriptional regulator
A1S_1878	ENOG4105MD1	YeeE YedE family protein
A1S_1880	ENOG4105DZG	Dehydrogenase
A1S_1881	ENOG4105TW1	Carbohydrate-selective porin OprB
A1S_1882	ENOG4106JPM	3-dehydroshikimate dehydratase
A1S_1883	ENOG4105FF2	Type I DHQase
A1S_1884	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
A1S_1885	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
A1S_1886	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
A1S_1887	ENOG4105D2S	major facilitator superfamily
A1S_1888	ENOG4105D2S	major facilitator superfamily
A1S_1889	ENOG4105F2Z	3-oxoadipate enol-lactonase
A1S_1890	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
A1S_1891	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_1892	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_1893	ENOG4107QNJ	CoA-transferase subunit B
A1S_1894	ENOG4107QP7	CoA-transferase subunit A
A1S_1896	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A1S_1897	ENOG4107VMU	Membrane
A1S_1905	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A1S_1908	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A1S_1910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A1S_1911	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A1S_1916	ENOG4105C7B	Threonine dehydratase
A1S_1918	ENOG4105CZN	Potassium uptake protein
A1S_1919	ENOG4105HDD	phospholipase
A1S_1921	ENOG4105E0K	tonB-dependent siderophore receptor
A1S_1923	ENOG4105PV3	Inner membrane protein yqiJ
A1S_1924	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A1S_1925	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A1S_1928	ENOG41068P6	UPF0319 protein
A1S_1930	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A1S_1935	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A1S_1936	ENOG4105C8Y	Acetylornithine aminotransferase
A1S_1937	ENOG4105M2J	Glutaredoxin
A1S_1939	ENOG4105CC0	LysR family Transcriptional regulator
A1S_1940	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A1S_1941	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A1S_1945	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A1S_1946	ENOG4105DE4	1-phosphofructokinase
A1S_1947	ENOG4105DM4	PTS System
A1S_1949	ENOG4105BZU	Histidine kinase
A1S_1951	ENOG4105D8V	Glucose sorbosone dehydrogenase
A1S_1952	ENOG4108RAV	Conserved protein
A1S_1953	ENOG4105CHH	sulfate transporter
A1S_1956	ENOG4105C85	amino acid
A1S_1958	ENOG4105F7P	transcriptional regulator AsnC family
A1S_1960	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
A1S_1961	ENOG4105VEJ	Heat shock protein
A1S_1963	ENOG4105Y3E	Modulates RecA activity (By similarity)
A1S_1965	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A1S_1969	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1S_1970	ENOG4105DZP	Membrane-associated zinc metalloprotease
A1S_1972	ENOG4105KNE	Phosphatidate cytidylyltransferase
A1S_1973	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A1S_1977	ENOG4105CUX	Signal transduction histidine kinase
A1S_1978	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A1S_1987	ENOG4105CMR	udp-glucose 4-epimerase
A1S_1988	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
A1S_1992	ENOG4105T38	integral membrane protein
A1S_1993	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A1S_1995	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A1S_1996	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A1S_2003	ENOG4108IFG	nitrite reductase, (NAD(P)H)
A1S_2004	ENOG4108IFG	nitrite reductase, (NAD(P)H)
A1S_2005	ENOG4107QZF	nitrite reductase NADPH large subunit
A1S_2006	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A1S_2010	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A1S_2011	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A1S_2013	ENOG4105D8G	Major Facilitator superfamily
A1S_2015	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A1S_2034	ENOG4105WXW	Antirepressor
A1S_2044	ENOG4105CBC	glutamate synthase
A1S_2046	ENOG4105CBC	glutamate synthase
A1S_2053	ENOG4105C0A	alcohol dehydrogenase
A1S_2055	ENOG4105HSS	phospholipase C
A1S_2056	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A1S_2061	ENOG4105CHR	reductase
A1S_2062	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_2064	ENOG4105C5Q	Transcriptional regulator
A1S_2065	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A1S_2066	ENOG4108NIW	Leucine export protein LeuE
A1S_2067	ENOG4105EW9	transcriptional regulator AsnC family
A1S_2068	ENOG4105DKK	Benzoate
A1S_2070	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A1S_2072	ENOG41081QV	Universal stress protein
A1S_2073	ENOG4105C5H	ABC transporter
A1S_2076	ENOG4105CNM	Receptor
A1S_2077	ENOG4105CNM	Receptor
A1S_2079	ENOG4105CUY	Mechanosensitive ion channel
A1S_2082	ENOG4105R8C	Transcriptional regulator
A1S_2083	ENOG4105EW9	transcriptional regulator AsnC family
A1S_2084	ENOG4105G7T	Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity)
A1S_2089	ENOG4108D1K	outer membrane usher protein
A1S_2092	ENOG4105CD8	aminopeptidase N
A1S_2097	ENOG4107QUV	Domain protein
A1S_2098	ENOG4105C0A	alcohol dehydrogenase
A1S_2101	ENOG4107RR1	TRANSCRIPTIONal
A1S_2103	ENOG4107R55	ethanolamine transporter
A1S_2104	ENOG4105CPD	ethanolamine ammonia-lyase
A1S_2105	ENOG4107FQ9	ethanolamine ammonia-lyase
A1S_2106	ENOG4107FQ9	ethanolamine ammonia-lyase
A1S_2107	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A1S_2111	ENOG4108RCM	Nitroreductase
A1S_2112	ENOG4108TZV	Membrane
A1S_2115	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A1S_2116	ENOG4105K8N	protein family UPF0079, ATPase
A1S_2122	ENOG4105DZ2	Transcriptional regulator
A1S_2124	ENOG4105F27	Major Facilitator
A1S_2125	ENOG4105EYW	Ion transport protein
A1S_2126	ENOG4107QIJ	Aconitate hydratase 2
A1S_2127	ENOG4107QIJ	Aconitate hydratase 2
A1S_2128	ENOG4107QIJ	Aconitate hydratase 2
A1S_2132	ENOG4105CFU	surface antigen
A1S_2133	ENOG4107S74	Lysophospholipid transporter LplT
A1S_2136	ENOG4105CFQ	glutamine synthetase
A1S_2137	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
A1S_2138	ENOG4105C08	Histidine kinase
A1S_2139	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
A1S_2140	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A1S_2141	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A1S_2142	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A1S_2144	ENOG4105KRF	dihydroneopterin aldolase
A1S_2146	ENOG4105D06	uba thif-type nad fad binding protein
A1S_2147	ENOG4108MEJ	flavin reductase domain protein
A1S_2149	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_2153	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A1S_2156	ENOG4105CC0	LysR family Transcriptional regulator
A1S_2158	ENOG4105DEN	Luciferase family
A1S_2160	ENOG4105CND	Glycosyl transferase, family 2
A1S_2161	ENOG4107BJW	polysaccharide deacetylase
A1S_2166	ENOG4105E2S	oxidase) subunit II
A1S_2167	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A1S_2168	ENOG4105CCU	oxidase (Subunit III)
A1S_2169	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
A1S_2175	ENOG4105CDU	Replicative dna helicase
A1S_2176	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A1S_2186	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
A1S_2187	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A1S_2188	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A1S_2189	ENOG4105C12	Phosphoribosylglycinamide synthetase
A1S_2192	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A1S_2193	ENOG4108UMI	ABC transporter, permease
A1S_2194	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A1S_2196	ENOG4105CK2	sodium dicarboxylate symporter
A1S_2204	ENOG4105DY2	Paraquat-inducible protein b
A1S_2205	ENOG4105F1S	paraquat-inducible protein a
A1S_2212	ENOG4105CSH	Transporter
A1S_2219	ENOG4105JXH	GntR family transcriptional regulator
A1S_2221	ENOG4105D6U	Sodium Glutamate Symporter
A1S_2232	ENOG4105C26	Dehydrogenase
A1S_2233	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A1S_2234	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A1S_2235	ENOG4105EVZ	LysR family transcriptional regulator
A1S_2240	ENOG4105D9P	serine threonine protein kinase
A1S_2245	ENOG4105VCC	30S ribosomal protein S21
A1S_2246	ENOG4105KTH	gatB Yqey
A1S_2247	ENOG4105ERG	peptidase m48, ste24p
A1S_2248	ENOG4105C5I	Dehydrogenase
A1S_2251	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A1S_2258	ENOG41069NU	Nitroreductase
A1S_2260	ENOG4105C1J	atp-dependent rna helicase
A1S_2261	ENOG4105VEQ	Cold shock protein
A1S_2262	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A1S_2263	ENOG4105M08	Membrane
A1S_2269	ENOG4105CYB	regulatoR
A1S_2270	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A1S_2271	ENOG4105E0Y	RtcB Protein
A1S_2274	ENOG4105CIN	aminoacyl-histidine dipeptidase
A1S_2276	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A1S_2277	ENOG4105CQC	Prephenate dehydratase
A1S_2278	ENOG4105NIV	Esterase
A1S_2279	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_2280	ENOG4105CK2	sodium dicarboxylate symporter
A1S_2281	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A1S_2282	ENOG4105VUT	cytoplasmic protein
A1S_2283	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A1S_2284	ENOG4105BZ4	penicillin-binding protein
A1S_2286	ENOG4105M6F	mutator MutT protein
A1S_2287	ENOG4105DHQ	Histidine kinase
A1S_2288	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A1S_2290	ENOG4107QHF	type ii secretion system protein e
A1S_2292	ENOG4108R96	Methyltransferase, YaeB family
A1S_2293	ENOG4105DP0	ferredoxin-NADP reductase
A1S_2294	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A1S_2295	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A1S_2296	ENOG4105CFP	Peptidase U32
A1S_2297	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
A1S_2299	ENOG4108JEH	abc transporter atp-binding protein
A1S_2300	ENOG4106YG3	ABC transporter
A1S_2301	ENOG4105DSP	amino acid AbC transporter
A1S_2302	ENOG4105E89	ABC transporter
A1S_2304	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A1S_2306	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A1S_2311	ENOG4105DA5	(ABC) transporter
A1S_2312	ENOG4105E3A	(ABC) transporter
A1S_2315	ENOG4105CNI	cell division protein FtsW
A1S_2316	ENOG4105CVE	Lytic murein transglycosylase
A1S_2323	ENOG4105CE9	30S ribosomal protein S2
A1S_2324	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A1S_2326	ENOG4107RNU	major facilitator superfamily MFS_1
A1S_2328	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
A1S_2329	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A1S_2330	ENOG4107QPN	acyl-Coa dehydrogenase
A1S_2331	ENOG4107QPN	acyl-Coa dehydrogenase
A1S_2334	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A1S_2335	ENOG4105SYT	Methylenetetrahydrofolate reductase
A1S_2336	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A1S_2337	ENOG4105BZU	Histidine kinase
A1S_2338	ENOG4105C6K	Malic enzyme
A1S_2340	ENOG4105C0H	protease
A1S_2342	ENOG4107QNR	UPF0135 protein
A1S_2343	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A1S_2349	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A1S_2351	ENOG4105C5F	glutamine synthetase
A1S_2352	ENOG4105C5F	glutamine synthetase
A1S_2353	ENOG4105DUX	Transporter
A1S_2355	ENOG4105DDQ	anthranilate synthase
A1S_2356	ENOG4105CD8	aminopeptidase N
A1S_2364	ENOG4105C7W	Xanthine dehydrogenase
A1S_2366	ENOG4105EUJ	GTP cyclohydrolase i
A1S_2369	ENOG4105NX3	Membrane
A1S_2377	ENOG4108JJB	ABC transporter
A1S_2380	ENOG4105WQI	isochorismatase
A1S_2381	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
A1S_2382	ENOG4105C0W	non-ribosomal peptide synthetase
A1S_2383	ENOG4105C0W	non-ribosomal peptide synthetase
A1S_2387	ENOG4108IPW	abc transporter atp-binding protein
A1S_2390	ENOG4105CEY	Amp-dependent synthetase and ligase
A1S_2393	ENOG4105WWK	YheO domain protein
A1S_2395	ENOG4105C2I	pirin domain protein
A1S_2402	ENOG4105D74	hydrolase
A1S_2403	ENOG4107RN6	Monooxygenase
A1S_2405	ENOG4105CR8	Transcriptional regulator
A1S_2406	ENOG4105CHJ	isochorismatase hydrolase
A1S_2416	ENOG4105VCD	cytoplasmic protein
A1S_2417	ENOG4105D22	carbon starvation protein
A1S_2418	ENOG4105D22	carbon starvation protein
A1S_2420	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A1S_2422	ENOG41066DG	(EAL) domain protein
A1S_2424	ENOG4105DHU	Bile acid
A1S_2425	ENOG4105DHU	Bile acid
A1S_2430	ENOG4105DAN	ATP-dependent protease
A1S_2431	ENOG4105EJC	lysr family transcriptional regulator
A1S_2432	ENOG4108K5P	(LipO)protein
A1S_2435	ENOG4105DZ1	carboxypeptidase
A1S_2436	ENOG4108Z0R	Transferase
A1S_2441	ENOG4107QTF	adenylosuccinate lyase
A1S_2444	ENOG4105ERU	peptidase
A1S_2445	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A1S_2447	ENOG4105C8U	phosphate abc transporter
A1S_2448	ENOG4105CVA	phosphate
A1S_2449	ENOG4105C85	amino acid
A1S_2450	ENOG4107RA9	decarboxylase
A1S_2451	ENOG4105F7P	transcriptional regulator AsnC family
A1S_2453	ENOG4105DY8	decarboxylase
A1S_2454	ENOG4108JPW	Aminotransferase
A1S_2457	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A1S_2459	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A1S_2462	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A1S_2463	ENOG4105D3G	Pseudouridine synthase
A1S_2465	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A1S_2471	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A1S_2472	ENOG4108ETY	sodium dicarboxylate symporter
A1S_2473	ENOG4105EGI	Transcriptional regulator
A1S_2476	ENOG4108R99	pseudouridine synthase
A1S_2477	ENOG4105E9K	Isocitrate dehydrogenase
A1S_2479	ENOG4105DZ1	carboxypeptidase
A1S_2480	ENOG4105CEP	NADH dehydrogenase
A1S_2481	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A1S_2482	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A1S_2485	ENOG4107R8N	Glycosyl transferase, family 2
A1S_2493	ENOG4105EA8	2-Nitropropane dioxygenase
A1S_2494	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A1S_2495	ENOG4107QS8	(LipO)protein
A1S_2502	ENOG4105DTR	rard protein
A1S_2504	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A1S_2506	ENOG4105BZU	Histidine kinase
A1S_2510	ENOG4105F7F	Chaperone
A1S_2514	ENOG4105EMU	Dehydrogenase
A1S_2515	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
A1S_2516	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A1S_2517	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
A1S_2518	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A1S_2521	ENOG4105C3F	Signal peptidase i
A1S_2523	ENOG41068WN	
A1S_2525	ENOG4105C0H	protease
A1S_2526	ENOG4108IYU	L-aspartate oxidase
A1S_2529	ENOG4105HHA	aminodeoxychorismate lyase
A1S_2531	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A1S_2532	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A1S_2534	ENOG4108I5D	sulfate abc transporter
A1S_2536	ENOG4108IJ6	ABC transporter
A1S_2537	ENOG4107R11	Transcriptional regulator
A1S_2540	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A1S_2542	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A1S_2545	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A1S_2548	ENOG4108UKI	Enoyl-CoA hydratase
A1S_2549	ENOG4105EGD	dinuclear metal center protein, YbgI family
A1S_2560	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
A1S_2561	ENOG4108JJA	ABC, transporter
A1S_2562	ENOG4107QI1	Mate efflux family protein
A1S_2571	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A1S_2572	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
A1S_2574	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
A1S_2575	ENOG4105CEY	Amp-dependent synthetase and ligase
A1S_2578	ENOG4105C0W	non-ribosomal peptide synthetase
A1S_2579	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
A1S_2580	ENOG4105WQI	isochorismatase
A1S_2581	ENOG4105E4F	Isochorismate synthase
A1S_2584	ENOG4105C2C	drug resistance transporter, Bcr CflA
A1S_2585	ENOG4108ETH	Formylglycinamide ribotide synthetase
A1S_2589	ENOG4105CH2	amidohydrolase
A1S_2590	ENOG4107YD3	Thioesterase
A1S_2591	ENOG4105E02	MotA TolQ exbB proton channel
A1S_2592	ENOG4105M8F	Biopolymer transport protein exbD tolR
A1S_2594	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A1S_2595	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A1S_2604	ENOG4105C02	permease
A1S_2606	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A1S_2607	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
A1S_2608	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A1S_2610	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
A1S_2611	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A1S_2612	ENOG4105D60	lipoprotein releasing system transmembrane protein
A1S_2620	ENOG4107KET	secretion protein, HlyD family
A1S_2626	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A1S_2627	ENOG4105C10	Electron transfer flavoprotein
A1S_2628	ENOG4105BZJ	Electron transfer flavoprotein
A1S_2629	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A1S_2630	ENOG4105N14	lysine exporter protein LysE YggA
A1S_2632	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A1S_2633	ENOG4105C85	amino acid
A1S_2634	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A1S_2636	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
A1S_2639	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A1S_2640	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
A1S_2641	ENOG4105BZW	Glycerate kinase
A1S_2651	ENOG4105CEY	Amp-dependent synthetase and ligase
A1S_2653	ENOG4108RRZ	Transcription elongation factor GreB
A1S_2657	ENOG4105E4C	Lytic transglycosylase catalytic
A1S_2660	ENOG4105BZS	acriflavin resistance protein
A1S_2661	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
A1S_2663	ENOG41080IJ	Diacylglycerol kinase
A1S_2666	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A1S_2669	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A1S_2670	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A1S_2671	ENOG4105CSH	Transporter
A1S_2680	ENOG4105EEI	dihydropteroate synthase
A1S_2681	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A1S_2683	ENOG4105HBR	Rna-binding protein
A1S_2686	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A1S_2687	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A1S_2689	ENOG4108IG5	Transcriptional regulator
A1S_2690	ENOG4108UQ8	endoribonuclease L-psp
A1S_2692	ENOG41080TK	Universal stress protein
A1S_2694	ENOG4105PNM	synthesis protein
A1S_2697	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A1S_2698	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A1S_2699	ENOG4105KVH	Transcriptional regulator
A1S_2701	ENOG4105CUB	amino acid
A1S_2704	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A1S_2705	ENOG41084BA	UPF0250 protein
A1S_2706	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A1S_2711	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
A1S_2712	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
A1S_2714	ENOG4105E33	succinate dehydrogenase
A1S_2715	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A1S_2716	ENOG4105C7S	Dehydrogenase
A1S_2717	ENOG4107QN2	dihydrolipoyl dehydrogenase
A1S_2719	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A1S_2721	ENOG4105CKW	Inner membrane protein yedI
A1S_2722	ENOG4105CGZ	zinc metallopeptidase
A1S_2723	ENOG4105EEQ	Na H antiporter
A1S_2725	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A1S_2729	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A1S_2734	ENOG410841Q	phosphoesterase PA-phosphatase related protein
A1S_2735	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A1S_2736	ENOG4105BZS	acriflavin resistance protein
A1S_2737	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A1S_2738	ENOG4105K8R	UPF0145 protein
A1S_2739	ENOG4105K8R	UPF0145 protein
A1S_2742	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A1S_2743	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A1S_2747	ENOG4108M0I	Transcriptional regulator
A1S_2750	ENOG4105DHQ	Histidine kinase
A1S_2751	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A1S_2752	ENOG4105DIJ	Phosphoethanolamine transferase
A1S_2756	ENOG4105D78	K07001 NTE family protein
A1S_2759	ENOG4105MSB	protein, conserved in bacteria
A1S_2760	ENOG4105CTB	Polyprenyl synthetase
A1S_2761	ENOG4105C7F	AcnD-accessory protein PrpF
A1S_2762	ENOG4105C85	amino acid
A1S_2763	ENOG4105C85	amino acid
A1S_2767	ENOG4105CF7	AraC family transcriptional regulator
A1S_2772	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
A1S_2774	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
A1S_2776	ENOG4105D8T	Acyltransferase
A1S_2777	ENOG4105C03	ribonuclease
A1S_2778	ENOG4108Z03	MAF-like protein
A1S_2779	ENOG4105VQ7	Rod shape-determining protein MreD
A1S_2780	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A1S_2781	ENOG4105DFF	Rod shape-determining protein mreb
A1S_2782	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A1S_2784	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A1S_2789	ENOG4105C9K	Endothelin-converting enzyme 1
A1S_2791	ENOG4105C7B	Threonine dehydratase
A1S_2792	ENOG4105D78	K07001 NTE family protein
A1S_2793	ENOG4105BZG	amino acid carrier protein
A1S_2795	ENOG4105C2C	drug resistance transporter, Bcr CflA
A1S_2796	ENOG4105EM2	membrane
A1S_2798	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A1S_2806	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A1S_2807	ENOG4105WD1	Membrane
A1S_2809	ENOG4106HKS	Entericidin EcnA/B family
A1S_2811	ENOG4105CBS	Chea signal transduction histidine kinase
A1S_2812	ENOG4105C8Q	Methyl-accepting chemotaxis
A1S_2813	ENOG4108ZGA	chew protein
A1S_2814	ENOG4105M3Z	response regulator
A1S_2815	ENOG4108UNF	response regulator
A1S_2820	ENOG4105KWI	UPF0339 protein
A1S_2821	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A1S_2822	ENOG4105K78	MarR family Transcriptional regulator
A1S_2824	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A1S_2825	ENOG4105T95	Thiol disulfide interChange protein
A1S_2827	ENOG4108N2Y	auxin Efflux
A1S_2828	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A1S_2829	ENOG4105CHB	tonB-dependent Receptor
A1S_2830	ENOG4108VX5	3-methyladenine DNA glycosylase
A1S_2832	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
A1S_2836	ENOG4105C2W	permease
A1S_2838	ENOG4108IQI	permease
A1S_2839	ENOG4105E0Y	RtcB Protein
A1S_2842	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_2844	ENOG410814C	multidrug resistance protein
A1S_2846	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A1S_2847	ENOG4105DZG	Dehydrogenase
A1S_2848	ENOG4105DZG	Dehydrogenase
A1S_2849	ENOG4105TW1	Carbohydrate-selective porin OprB
A1S_2851	ENOG4108R6W	Transcriptional regulator, ARAC family
A1S_2852	ENOG4105CHU	acetyl-coa acetyltransferase
A1S_2853	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A1S_2854	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A1S_2857	ENOG41082BV	acetyltransferase
A1S_2859	ENOG4108UT2	hemolysin iii
A1S_2860	ENOG4105CSH	Transporter
A1S_2863	ENOG4105D3R	alkyl hydroperoxide reductase
A1S_2868	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A1S_2875	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A1S_2877	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A1S_2878	ENOG4108WBT	adenosyltransferase
A1S_2882	ENOG4105CNG	UPF0061 protein
A1S_2883	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A1S_2884	ENOG4105EB3	Histidine kinase
A1S_2886	ENOG4105CSU	acyl-Coa dehydrogenase
A1S_2887	ENOG4105CSU	acyl-Coa dehydrogenase
A1S_2888	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
A1S_2892	ENOG4105UGU	tonB-dependent Receptor
A1S_2897	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A1S_2899	ENOG4108PQP	glycosyl transferase group 1
A1S_2901	ENOG4107BJW	polysaccharide deacetylase
A1S_2904	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A1S_2905	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A1S_2906	ENOG4105BZU	Histidine kinase
A1S_2907	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A1S_2913	ENOG4105VIE	preprotein translocase, subunit YajC
A1S_2914	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A1S_2915	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A1S_2916	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A1S_2917	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A1S_2919	ENOG4105FFC	UPF0187 protein
A1S_2920	ENOG4105DB7	PHP domain protein
A1S_2922	ENOG4105K9H	YciI-like protein
A1S_2927	ENOG4105DFP	Integrase
A1S_2930	ENOG4105CE1	Ferrous iron transport protein b
A1S_2932	ENOG4108IJF	Heavy metal efflux pump, CzcA
A1S_2936	ENOG4105E3B	Multicopper oxidase
A1S_2938	ENOG4105GR3	Histidine kinase
A1S_2947	ENOG4105NAU	thioesterase Superfamily protein
A1S_2950	ENOG4107U2T	alpha beta
A1S_2951	ENOG4107QPB	Beta-lactamase domain protein
A1S_2955	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A1S_2962	ENOG4105CVE	Lytic murein transglycosylase
A1S_2963	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A1S_2964	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A1S_2966	ENOG4105DFU	Cell wall formation (By similarity)
A1S_2968	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
A1S_2969	ENOG4105DU1	integral membrane protein, terc
A1S_2970	ENOG4106032	Glutathionylspermidine synthase
A1S_2972	ENOG4107QUY	Guanine deaminase
A1S_2973	ENOG4107QUY	Guanine deaminase
A1S_2974	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A1S_2976	ENOG4105T95	Thiol disulfide interChange protein
A1S_2977	ENOG4105PGM	cation diffusion facilitator family transporter
A1S_2980	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A1S_2981	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A1S_2984	ENOG4105VG0	50S ribosomal protein l34
A1S_2986	ENOG4108KHX	Diguanylate cyclase
A1S_2987	ENOG4105UYK	outer membrane protein a
A1S_2989	ENOG4107RZC	phospholipase d
A1S_2991	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A1S_2997	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A1S_2998	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A1S_2999	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A1S_3001	ENOG4108UJD	30S ribosomal protein S9
A1S_3002	ENOG4107MKT	Stringent starvation protein a
A1S_3003	ENOG4105KB2	stringent starvation protein b
A1S_3007	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_3008	ENOG4107QX3	carboxylase
A1S_3011	ENOG4108RZE	Tetr family transcriptional regulator
A1S_3012	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_3017	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
A1S_3021	ENOG4105D6S	protein involved in catabolism of external DNA
A1S_3027	ENOG4105E4C	Lytic transglycosylase catalytic
A1S_3030	ENOG4105C9A	Phoh family
A1S_3036	ENOG4105CS1	NAD(P)H quinone oxidoreductase
A1S_3037	ENOG4107S2Z	UPF0761 membrane protein
A1S_3039	ENOG4108K2B	transcriptional regulator
A1S_3040	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
A1S_3045	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A1S_3047	ENOG4105DGW	oligopeptidase A
A1S_3048	ENOG4105VKU	nucleicacid-binding protein
A1S_3053	ENOG4105C1G	acyl-Coa dehydrogenase
A1S_3058	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A1S_3060	ENOG41067V7	50S ribosomal protein L36
A1S_3061	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A1S_3082	ENOG41089BK	Glutamine amido-transferase
A1S_3083	ENOG4105C28	cystathionine
A1S_3084	ENOG4105D7A	ATP-binding protein
A1S_3086	ENOG4105KPV	Transcriptional regulator
A1S_3089	ENOG4105CK2	sodium dicarboxylate symporter
A1S_3090	ENOG4105C29	acyl-CoA thioesterase
A1S_3095	ENOG4105CB5	ATP-dependent DNA helicase recG
A1S_3096	ENOG4105MJ2	Competence protein
A1S_3097	ENOG4108URH	decarboxylase
A1S_3098	ENOG4107QUT	magnesium and cobalt transport protein CorA
A1S_3100	ENOG4105E3I	toluene tolerance
A1S_3102	ENOG4105CY3	ABC transporter, permease
A1S_3103	ENOG4105DHJ	ABC, transporter
A1S_3104	ENOG4105C1J	atp-dependent rna helicase
A1S_3105	ENOG4105ECY	inositol monophosphatase
A1S_3108	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A1S_3111	ENOG4105CSU	acyl-Coa dehydrogenase
A1S_3113	ENOG41067S9	phage shock protein C, PspC
A1S_3114	ENOG4105W87	Cbs domain
A1S_3126	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A1S_3130	ENOG4105C26	Dehydrogenase
A1S_3132	ENOG4105C8Y	Acetylornithine aminotransferase
A1S_3134	ENOG4105D82	Glutamate dehydrogenase
A1S_3135	ENOG4108IQI	permease
A1S_3142	ENOG4105IPI	Membrane
A1S_3143	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A1S_3144	ENOG4105EM2	membrane
A1S_3145	ENOG4105EM2	membrane
A1S_3146	ENOG4107QF7	multi-drug
A1S_3148	ENOG4105NF4	modulator of drug activity
A1S_3149	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
A1S_3151	ENOG4105CQB	FAD linked oxidase domain protein
A1S_3152	ENOG4108JQ1	Dehydrogenase
A1S_3158	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A1S_3159	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
A1S_3160	ENOG4107IFA	Lipase (EC 3.1.1.3)
A1S_3163	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A1S_3170	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A1S_3172	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A1S_3173	ENOG4105KME	endoribonuclease L-psp
A1S_3175	ENOG4108UQY	Iron-storage protein
A1S_3176	ENOG4108YSG	O-Antigen polymerase
A1S_3179	ENOG4105HA9	of methanol dehydrogenase type
A1S_3180	ENOG4108V0P	LemA family
A1S_3182	ENOG4105BZ8	glutamate synthase
A1S_3185	ENOG4105CBC	glutamate synthase
A1S_3191	ENOG4105E4G	Type IV pilus
A1S_3196	ENOG4108JQC	penicillin-binding protein 1A
A1S_3197	ENOG4108JQC	penicillin-binding protein 1A
A1S_3198	ENOG4105DHI	Methyltransferase
A1S_3202	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A1S_3203	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A1S_3204	ENOG4105CJN	penicillin-binding protein
A1S_3207	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A1S_3211	ENOG4108IQI	permease
A1S_3221	ENOG4105C5H	ABC transporter
A1S_3224	ENOG4105PDP	Short chain dehydrogenase
A1S_3225	ENOG4105CHH	sulfate transporter
A1S_3227	ENOG4105BZM	domain protein
A1S_3228	ENOG4105BZM	domain protein
A1S_3229	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A1S_3230	ENOG4105E0F	Histidine kinase
A1S_3231	ENOG4105CYC	Transferase
A1S_3235	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A1S_3241	ENOG41061CK	Antibiotic biosynthesis monooxygenase
A1S_3244	ENOG4105CUV	Homoserine Kinase
A1S_3255	ENOG4108UQN	AraC family transcriptional regulator
A1S_3256	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
A1S_3258	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A1S_3259	ENOG4105KVH	Transcriptional regulator
A1S_3262	ENOG4105KVH	Transcriptional regulator
A1S_3265	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
A1S_3266	ENOG4105CPC	Aldo Keto reductase
A1S_3271	ENOG4107RSM	transcriptional regulator
A1S_3272	ENOG4105D94	Major Facilitator Superfamily
A1S_3277	ENOG4105EUB	pirin domain protein
A1S_3278	ENOG4105CHJ	isochorismatase hydrolase
A1S_3280	ENOG4105C26	Dehydrogenase
A1S_3281	ENOG4108JPW	Aminotransferase
A1S_3283	ENOG4105C85	amino acid
A1S_3285	ENOG4108UMN	azlc family
A1S_3287	ENOG4108UUM	single-stranded DNA-binding protein
A1S_3288	ENOG4107RDB	Major Facilitator
A1S_3290	ENOG4105DWF	phosphomethylpyrimidine kinase
A1S_3291	ENOG4105RA2	Membrane
A1S_3293	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A1S_3294	ENOG4108WUH	Transcriptional regulator, TetR family
A1S_3295	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A1S_3296	ENOG4105BZU	Histidine kinase
A1S_3298	ENOG4105C94	Transporter
A1S_3300	ENOG4107QN1	sodium solute
A1S_3301	ENOG41062QD	Membrane
A1S_3302	ENOG4105BZU	Histidine kinase
A1S_3305	ENOG4108UZX	fmn reductase
A1S_3306	ENOG4105FBW	Monooxygenase
A1S_3308	ENOG4108W2Y	isochorismatase
A1S_3309	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A1S_3311	ENOG4105D64	Mechanosensitive ion channel
A1S_3313	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A1S_3314	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A1S_3318	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A1S_3321	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A1S_3324	ENOG4105E0K	tonB-dependent siderophore receptor
A1S_3327	ENOG4107QSN	dihydrolipoamide acetyltransferase
A1S_3328	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A1S_3329	ENOG41063SB	peptidase
A1S_3331	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A1S_3332	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A1S_3333	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
A1S_3337	ENOG4105D7Z	glutathione synthase
A1S_3341	ENOG4105CGK	Exodeoxyribonuclease III
A1S_3342	ENOG4105KUZ	arsenate reductase
A1S_3345	ENOG4105BZU	Histidine kinase
A1S_3346	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A1S_3347	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A1S_3353	ENOG41084YZ	Hydrolase
A1S_3356	ENOG41061H0	Monooxygenase
A1S_3358	ENOG4108Z2U	ureidoglycolate hydrolase
A1S_3359	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A1S_3360	ENOG4105IPS	esterase
A1S_3364	ENOG4105CS6	Rhs element vgr protein
A1S_3366	ENOG4105D9M	gamma-glutamylcysteine synthetase
A1S_3369	ENOG4106BRA	Membrane
A1S_3370	ENOG4105CHM	Aminotransferase
A1S_3371	ENOG4107QJQ	Mate efflux family protein
A1S_3374	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A1S_3375	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A1S_3376	ENOG4105BZU	Histidine kinase
A1S_3379	ENOG4105KHC	sulfurtransferase
A1S_3386	ENOG4105EAC	phosphoserine phosphatase
A1S_3388	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A1S_3391	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A1S_3392	ENOG4108ZAI	phosphatidylglycerophosphatase a
A1S_3395	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A1S_3396	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A1S_3397	ENOG4108NIW	Leucine export protein LeuE
A1S_3402	ENOG41088SP	formiminoglutamate hydrolase
A1S_3404	ENOG4105C85	amino acid
A1S_3408	ENOG41090B9	response to stress
A1S_3409	ENOG4105CZE	histidine utilization repressor
A1S_3411	ENOG4105CKI	cobalamin synthesis protein
A1S_3413	ENOG4105C85	amino acid
A1S_3415	ENOG4108RXX	maleylacetoacetate isomerase
A1S_3419	ENOG4105EWC	Purine nucleoside phosphorylase
A1S_3420	ENOG4107QI1	Mate efflux family protein
A1S_3421	ENOG4105C09	Bile acid
A1S_3422	ENOG4108RWI	nicotinamidase
A1S_3423	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A1S_3426	ENOG4105S64	Formate nitrite transporter
A1S_3427	ENOG4105D1H	recombination factor protein RarA
A1S_3429	ENOG4108ZZ3	UPF0260 protein
A1S_3432	ENOG4105CEN	a g-specific adenine glycosylase
A1S_3435	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A1S_3436	ENOG4105DQ4	alcohol dehydrogenase
A1S_3438	ENOG4105HEI	LysR family (Transcriptional regulator
A1S_3439	ENOG4105CV8	reductase
A1S_3440	ENOG4105F27	Major Facilitator
A1S_3445	ENOG4105BZS	acriflavin resistance protein
A1S_3446	ENOG4105BZS	acriflavin resistance protein
A1S_3447	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A1S_3448	ENOG4108IG5	Transcriptional regulator
A1S_3450	ENOG4105C2W	permease
A1S_3451	ENOG4105C2W	permease
A1S_3457	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A1S_3458	ENOG4105C8J	)-transporter
A1S_3462	ENOG4105RQF	LysR family Transcriptional regulator
A1S_3463	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A1S_3469	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
A1S_3474	ENOG4107ZQV	short-chain dehydrogenase reductase
A1S_3475	ENOG4105UGU	tonB-dependent Receptor
A1S_3529	ENOG4105FA0	parb-like partition protein
A1S_3589	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
A1S_3665	ENOG4105CYM	Glutathione S-transferase
A1S_3666	ENOG4105VAW	lrga family
A1S_3668	ENOG4108JU3	Alkyl hydroperoxide reductase
A1S_3670	ENOG4105ZED	uncharacterized protein ygaH
A1S_3721	ENOG4108IND	Tetr family transcriptional regulator
A1S_3785	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A1S_3792	ENOG4106FQ9	Biofilm PGA synthesis protein PgaD
A1S_3809	ENOG4105C85	amino acid
A1S_3813	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A1S_3858	ENOG4105XWI	UPF0304 protein
A1S_3906	ENOG4105CH6	catalase