locus-tag class description AUO97_00030 ENOG4105H4F exported protein AUO97_00065 ENOG4105C26 Dehydrogenase AUO97_00070 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AUO97_00075 ENOG4105EVZ LysR family transcriptional regulator AUO97_00100 ENOG4105D9P serine threonine protein kinase AUO97_00125 ENOG4105VCC 30S ribosomal protein S21 AUO97_00130 ENOG4105KTH gatB Yqey AUO97_00135 ENOG4105ERG peptidase m48, ste24p AUO97_00140 ENOG4105C5I Dehydrogenase AUO97_00155 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase AUO97_00190 ENOG41069NU Nitroreductase AUO97_00200 ENOG4105C1J atp-dependent rna helicase AUO97_00205 ENOG4105VEQ Cold shock protein AUO97_00215 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AUO97_00220 ENOG4105M08 Membrane AUO97_00250 ENOG4105CYB regulatoR AUO97_00255 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AUO97_00260 ENOG4105E0Y RtcB Protein AUO97_00280 ENOG4105CIN aminoacyl-histidine dipeptidase AUO97_00290 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase AUO97_00295 ENOG4105CQC Prephenate dehydratase AUO97_00300 ENOG4105NIV Esterase AUO97_00305 ENOG4105C1G acyl-Coa dehydrogenase AUO97_00310 ENOG4105CK2 sodium dicarboxylate symporter AUO97_00320 ENOG4108I0Q anthranilate phosphoribosyltransferase AUO97_00325 ENOG4105VUT cytoplasmic protein AUO97_00330 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AUO97_00335 ENOG4105BZ4 penicillin-binding protein AUO97_00345 ENOG4105M6F mutator MutT protein AUO97_00355 ENOG4105DHQ Histidine kinase AUO97_00360 ENOG4105XJC Two component transcriptional regulator (Winged helix family AUO97_00370 ENOG4107QHF type ii secretion system protein e AUO97_00380 ENOG4108R96 Methyltransferase, YaeB family AUO97_00385 ENOG4105DP0 ferredoxin-NADP reductase AUO97_00390 ENOG4105JAB phenazine biosynthesis protein, phzf family AUO97_00395 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AUO97_00400 ENOG4105CFP Peptidase U32 AUO97_00405 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AUO97_00415 ENOG4108JEH abc transporter atp-binding protein AUO97_00420 ENOG4106YG3 ABC transporter AUO97_00425 ENOG4105DSP amino acid AbC transporter AUO97_00430 ENOG4105E89 ABC transporter AUO97_00440 ENOG4105ENT Efflux transporter rnd family, mfp subunit AUO97_00450 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AUO97_00480 ENOG4105DA5 (ABC) transporter AUO97_00485 ENOG4105E3A (ABC) transporter AUO97_00500 ENOG4105CNI cell division protein FtsW AUO97_00505 ENOG4105CVE Lytic murein transglycosylase AUO97_00545 ENOG4105CE9 30S ribosomal protein S2 AUO97_00550 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AUO97_00560 ENOG4107RNU major facilitator superfamily MFS_1 AUO97_00570 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) AUO97_00575 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) AUO97_00580 ENOG4107QPN acyl-Coa dehydrogenase AUO97_00595 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) AUO97_00600 ENOG4105SYT Methylenetetrahydrofolate reductase AUO97_00605 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AUO97_00610 ENOG4105BZU Histidine kinase AUO97_00615 ENOG4105C6K Malic enzyme AUO97_00625 ENOG4105C0H protease AUO97_00630 ENOG4107QNR UPF0135 protein AUO97_00635 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AUO97_00670 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) AUO97_00680 ENOG4105C5F glutamine synthetase AUO97_00685 ENOG4105DUX Transporter AUO97_00695 ENOG4105DDQ anthranilate synthase AUO97_00700 ENOG4105CD8 aminopeptidase N AUO97_00730 ENOG4105C7W Xanthine dehydrogenase AUO97_00740 ENOG4105EUJ GTP cyclohydrolase i AUO97_00760 ENOG4105NX3 Membrane AUO97_00795 ENOG4105BZ1 (ABC) transporter AUO97_00805 ENOG4105WQI isochorismatase AUO97_00810 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AUO97_00815 ENOG4105C0W non-ribosomal peptide synthetase AUO97_00835 ENOG4108IPW abc transporter atp-binding protein AUO97_00850 ENOG4105CEY Amp-dependent synthetase and ligase AUO97_00865 ENOG4105WWK YheO domain protein AUO97_00875 ENOG4105C2I pirin domain protein AUO97_00925 ENOG4105D74 hydrolase AUO97_00930 ENOG4107RN6 Monooxygenase AUO97_00940 ENOG4105CR8 Transcriptional regulator AUO97_00945 ENOG4105CHJ isochorismatase hydrolase AUO97_00985 ENOG4105VCD cytoplasmic protein AUO97_00990 ENOG4105D22 carbon starvation protein AUO97_01000 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AUO97_01010 ENOG41066DG (EAL) domain protein AUO97_01020 ENOG4105DHU Bile acid AUO97_01035 ENOG4105DAN ATP-dependent protease AUO97_01040 ENOG4105EJC lysr family transcriptional regulator AUO97_01045 ENOG4108K5P (LipO)protein AUO97_01065 ENOG4105DZ1 carboxypeptidase AUO97_01070 ENOG4108Z0R Transferase AUO97_01090 ENOG4107QTF adenylosuccinate lyase AUO97_01105 ENOG4105ERU peptidase AUO97_01110 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AUO97_01120 ENOG4105C8U phosphate abc transporter AUO97_01125 ENOG4105CVA phosphate AUO97_01130 ENOG4105C85 amino acid AUO97_01135 ENOG4107RA9 decarboxylase AUO97_01140 ENOG4105F7P transcriptional regulator AsnC family AUO97_01150 ENOG4105DY8 decarboxylase AUO97_01155 ENOG4108JPW Aminotransferase AUO97_01170 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AUO97_01180 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AUO97_01195 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) AUO97_01200 ENOG4105D3G Pseudouridine synthase AUO97_01215 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) AUO97_01245 ENOG4105JAB phenazine biosynthesis protein, phzf family AUO97_01250 ENOG4108ETY sodium dicarboxylate symporter AUO97_01255 ENOG4105EGI Transcriptional regulator AUO97_01260 ENOG4105CBP Major Facilitator AUO97_01280 ENOG4108R99 pseudouridine synthase AUO97_01285 ENOG4105E9K Isocitrate dehydrogenase AUO97_01295 ENOG4105DZ1 carboxypeptidase AUO97_01300 ENOG4105CEP NADH dehydrogenase AUO97_01305 ENOG4108YZY peptidylprolyl cis-trans isomerase AUO97_01310 ENOG4105CVP deoxyribo-dipyrimidine photolyase AUO97_01325 ENOG4107R8N Glycosyl transferase, family 2 AUO97_01355 ENOG4105EA8 2-Nitropropane dioxygenase AUO97_01360 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AUO97_01365 ENOG4107QS8 (LipO)protein AUO97_01400 ENOG4105DTR rard protein AUO97_01410 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) AUO97_01420 ENOG4105BZU Histidine kinase AUO97_01440 ENOG4105F7F Chaperone AUO97_01465 ENOG4105EMU Dehydrogenase AUO97_01470 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase AUO97_01475 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) AUO97_01480 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) AUO97_01490 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) AUO97_01505 ENOG4105C3F Signal peptidase i AUO97_01515 ENOG41068WN AUO97_01525 ENOG4105C0H protease AUO97_01530 ENOG4108IYU L-aspartate oxidase AUO97_01545 ENOG4105HHA aminodeoxychorismate lyase AUO97_01550 ENOG4105YAZ 4-amino-4-deoxychorismate lyase AUO97_01555 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AUO97_01565 ENOG4108I5D sulfate abc transporter AUO97_01575 ENOG4108IJ6 ABC transporter AUO97_01580 ENOG4107R11 Transcriptional regulator AUO97_01595 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AUO97_01600 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) AUO97_01615 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AUO97_01630 ENOG4108UKI Enoyl-CoA hydratase AUO97_01635 ENOG4105EGD dinuclear metal center protein, YbgI family AUO97_01685 ENOG4105MP0 transposase AUO97_01710 ENOG4105C42 Type I secretion membrane fusion protein (HlyD AUO97_01715 ENOG4108JJA ABC, transporter AUO97_01720 ENOG4107QI1 Mate efflux family protein AUO97_01765 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AUO97_01770 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) AUO97_01775 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AUO97_01780 ENOG4105CEY Amp-dependent synthetase and ligase AUO97_01785 ENOG4105C0W non-ribosomal peptide synthetase AUO97_01790 ENOG4105C0W non-ribosomal peptide synthetase AUO97_01795 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase AUO97_01800 ENOG4105WQI isochorismatase AUO97_01805 ENOG4105E4F Isochorismate synthase AUO97_01835 ENOG4108ETH Formylglycinamide ribotide synthetase AUO97_01855 ENOG4105CH2 amidohydrolase AUO97_01860 ENOG4107YD3 Thioesterase AUO97_01865 ENOG4105E02 MotA TolQ exbB proton channel AUO97_01870 ENOG4105M8F Biopolymer transport protein exbD tolR AUO97_01880 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) AUO97_01885 ENOG4105KCK Peptidoglycan-associated lipoprotein AUO97_01935 ENOG4105C02 permease AUO97_01945 ENOG4108V3E phosphoribosylglycinamide formyltransferase AUO97_01950 ENOG4107R6F Alpha Beta Hydrolase Fold protein AUO97_01955 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AUO97_01965 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 AUO97_01970 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) AUO97_01975 ENOG4105D60 lipoprotein releasing system transmembrane protein AUO97_02005 ENOG4107KET secretion protein, HlyD family AUO97_02040 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AUO97_02045 ENOG4105C10 Electron transfer flavoprotein AUO97_02050 ENOG4105BZJ Electron transfer flavoprotein AUO97_02055 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AUO97_02060 ENOG4105N14 lysine exporter protein LysE YggA AUO97_02070 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AUO97_02080 ENOG4105C85 amino acid AUO97_02085 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AUO97_02095 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) AUO97_02110 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) AUO97_02115 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit AUO97_02120 ENOG4105BZW Glycerate kinase AUO97_02195 ENOG4105YCT UPF0386 protein AUO97_02205 ENOG4105CEY Amp-dependent synthetase and ligase AUO97_02220 ENOG4108RRZ Transcription elongation factor GreB AUO97_02245 ENOG4105E4C Lytic transglycosylase catalytic AUO97_02260 ENOG4105BZS acriflavin resistance protein AUO97_02265 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase AUO97_02275 ENOG41080IJ Diacylglycerol kinase AUO97_02290 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) AUO97_02305 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AUO97_02310 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AUO97_02315 ENOG4105CSH Transporter AUO97_02365 ENOG4105EEI dihydropteroate synthase AUO97_02370 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AUO97_02380 ENOG4105HBR Rna-binding protein AUO97_02400 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AUO97_02405 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AUO97_02415 ENOG4108IG5 Transcriptional regulator AUO97_02420 ENOG4108UQ8 endoribonuclease L-psp AUO97_02430 ENOG41080TK Universal stress protein AUO97_02445 ENOG4105PNM synthesis protein AUO97_02460 ENOG4105EEQ Na H antiporter AUO97_02465 ENOG4105CGZ zinc metallopeptidase AUO97_02470 ENOG4105CKW Inner membrane protein yedI AUO97_02480 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AUO97_02490 ENOG4107QN2 dihydrolipoyl dehydrogenase AUO97_02495 ENOG4105C7S Dehydrogenase AUO97_02500 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 AUO97_02510 ENOG4105E33 succinate dehydrogenase AUO97_02520 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein AUO97_02525 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit AUO97_02560 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AUO97_02565 ENOG41084BA UPF0250 protein AUO97_02570 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) AUO97_02585 ENOG4105CUB amino acid AUO97_02595 ENOG4105KVH Transcriptional regulator AUO97_02600 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AUO97_02605 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AUO97_02620 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) AUO97_02650 ENOG410841Q phosphoesterase PA-phosphatase related protein AUO97_02655 ENOG4105C1P efflux transporter, rnd family, mfp subunit AUO97_02660 ENOG4105BZS acriflavin resistance protein AUO97_02665 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AUO97_02670 ENOG4105K8R UPF0145 protein AUO97_02675 ENOG4105K8R UPF0145 protein AUO97_02695 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AUO97_02715 ENOG4108M0I Transcriptional regulator AUO97_02735 ENOG4105DHQ Histidine kinase AUO97_02740 ENOG4105XJC Two component transcriptional regulator (Winged helix family AUO97_02745 ENOG4105DIJ Phosphoethanolamine transferase AUO97_02765 ENOG4105D78 K07001 NTE family protein AUO97_02780 ENOG4105MSB protein, conserved in bacteria AUO97_02785 ENOG4105CTB Polyprenyl synthetase AUO97_02790 ENOG4105C7F AcnD-accessory protein PrpF AUO97_02795 ENOG4105C85 amino acid AUO97_02815 ENOG4105CF7 AraC family transcriptional regulator AUO97_02840 ENOG4108X0B nad(p)h dehydrogenase (quinone) AUO97_02850 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein AUO97_02860 ENOG4105D8T Acyltransferase AUO97_02865 ENOG4105C03 ribonuclease AUO97_02870 ENOG4108Z03 MAF-like protein AUO97_02875 ENOG4105VQ7 Rod shape-determining protein MreD AUO97_02880 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AUO97_02885 ENOG4105DFF Rod shape-determining protein mreb AUO97_02890 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AUO97_02900 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AUO97_02925 ENOG4105C9K Endothelin-converting enzyme 1 AUO97_02935 ENOG4105C7B Threonine dehydratase AUO97_02940 ENOG4105D78 K07001 NTE family protein AUO97_02945 ENOG4105BZG amino acid carrier protein AUO97_02960 ENOG4105C2C drug resistance transporter, Bcr CflA AUO97_02965 ENOG4105EM2 membrane AUO97_02975 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AUO97_03015 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AUO97_03020 ENOG4105WD1 Membrane AUO97_03030 ENOG4106HKS Entericidin EcnA/B family AUO97_03045 ENOG4105CBS Chea signal transduction histidine kinase AUO97_03050 ENOG4105C8Q Methyl-accepting chemotaxis AUO97_03055 ENOG4108ZGA chew protein AUO97_03060 ENOG4105M3Z response regulator AUO97_03065 ENOG4108UNF response regulator AUO97_03090 ENOG4105KWI UPF0339 protein AUO97_03095 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AUO97_03100 ENOG4105K78 MarR family Transcriptional regulator AUO97_03110 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) AUO97_03115 ENOG4105T95 Thiol disulfide interChange protein AUO97_03130 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AUO97_03135 ENOG4105CHB tonB-dependent Receptor AUO97_03140 ENOG4108VX5 3-methyladenine DNA glycosylase AUO97_03150 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AUO97_03170 ENOG4105C2W permease AUO97_03180 ENOG4108IQI permease AUO97_03185 ENOG4105E0Y RtcB Protein AUO97_03205 ENOG4105CHU acetyl-coa acetyltransferase AUO97_03215 ENOG410814C multidrug resistance protein AUO97_03225 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) AUO97_03230 ENOG4105DZG Dehydrogenase AUO97_03235 ENOG4105TW1 Carbohydrate-selective porin OprB AUO97_03245 ENOG4108R6W Transcriptional regulator, ARAC family AUO97_03250 ENOG4105CHU acetyl-coa acetyltransferase AUO97_03270 ENOG41082BV acetyltransferase AUO97_03280 ENOG4108UT2 hemolysin iii AUO97_03285 ENOG4105CSH Transporter AUO97_03300 ENOG4105D3R alkyl hydroperoxide reductase AUO97_03320 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AUO97_03355 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AUO97_03365 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) AUO97_03370 ENOG4108WBT adenosyltransferase AUO97_03390 ENOG4105CNG UPF0061 protein AUO97_03395 ENOG4105E3W Two component transcriptional regulator (Winged helix family AUO97_03400 ENOG4105EB3 Histidine kinase AUO97_03410 ENOG4105CSU acyl-Coa dehydrogenase AUO97_03415 ENOG4105CSU acyl-Coa dehydrogenase AUO97_03420 ENOG4108VY7 phosphate-starvation-inducible protein PsiE AUO97_03440 ENOG4105UGU tonB-dependent Receptor AUO97_03465 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AUO97_03480 ENOG4108PQP glycosyl transferase group 1 AUO97_03490 ENOG4107BJW polysaccharide deacetylase AUO97_03505 ENOG4105CM2 brancheD-chain amino acid aminotransferase AUO97_03510 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) AUO97_03515 ENOG4105BZU Histidine kinase AUO97_03535 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) AUO97_03590 ENOG4105VIE preprotein translocase, subunit YajC AUO97_03595 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AUO97_03600 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AUO97_03605 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AUO97_03615 ENOG4105FFC UPF0187 protein AUO97_03620 ENOG4105DB7 PHP domain protein AUO97_03630 ENOG4105K9H YciI-like protein AUO97_03655 ENOG4105DFP Integrase AUO97_03695 ENOG4105CE1 Ferrous iron transport protein b AUO97_03705 ENOG4108IJF Heavy metal efflux pump, CzcA AUO97_03730 ENOG4105E3B Multicopper oxidase AUO97_03745 ENOG4105GR3 Histidine kinase AUO97_03820 ENOG4105XWI UPF0304 protein AUO97_03855 ENOG4105NAU thioesterase Superfamily protein AUO97_03865 ENOG4107U2T alpha beta AUO97_03870 ENOG4107QPB Beta-lactamase domain protein AUO97_03915 ENOG4108KHX Diguanylate cyclase AUO97_03920 ENOG4105UYK outer membrane protein a AUO97_03930 ENOG4107RZC phospholipase d AUO97_03940 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AUO97_03960 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) AUO97_03965 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) AUO97_03970 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) AUO97_03980 ENOG4108UJD 30S ribosomal protein S9 AUO97_03985 ENOG4107MKT Stringent starvation protein a AUO97_03990 ENOG4105KB2 stringent starvation protein b AUO97_04010 ENOG4105C1G acyl-Coa dehydrogenase AUO97_04015 ENOG4107QX3 carboxylase AUO97_04030 ENOG4108RZE Tetr family transcriptional regulator AUO97_04035 ENOG4105C1G acyl-Coa dehydrogenase AUO97_04080 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase AUO97_04085 ENOG4105D6S protein involved in catabolism of external DNA AUO97_04115 ENOG4105E4C Lytic transglycosylase catalytic AUO97_04125 ENOG4105C9A Phoh family AUO97_04155 ENOG4105CS1 NAD(P)H quinone oxidoreductase AUO97_04160 ENOG4107S2Z UPF0761 membrane protein AUO97_04170 ENOG4108K2B transcriptional regulator AUO97_04175 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase AUO97_04220 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AUO97_04225 ENOG4105DGW oligopeptidase A AUO97_04230 ENOG4105VKU nucleicacid-binding protein AUO97_04265 ENOG4105C1G acyl-Coa dehydrogenase AUO97_04290 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) AUO97_04300 ENOG41067V7 50S ribosomal protein L36 AUO97_04305 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AUO97_04415 ENOG41089BK Glutamine amido-transferase AUO97_04420 ENOG4105C28 cystathionine AUO97_04425 ENOG4105D7A ATP-binding protein AUO97_04435 ENOG4105KPV Transcriptional regulator AUO97_04450 ENOG4105CK2 sodium dicarboxylate symporter AUO97_04455 ENOG4105C29 acyl-CoA thioesterase AUO97_04475 ENOG4105CB5 ATP-dependent DNA helicase recG AUO97_04480 ENOG4105MJ2 Competence protein AUO97_04490 ENOG4108URH decarboxylase AUO97_04495 ENOG4105D7N magnesium and cobalt transport protein CorA AUO97_04505 ENOG4105E3I toluene tolerance AUO97_04515 ENOG4105CY3 ABC transporter, permease AUO97_04520 ENOG4105DHJ ABC, transporter AUO97_04525 ENOG4105C1J atp-dependent rna helicase AUO97_04530 ENOG4105ECY inositol monophosphatase AUO97_04545 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) AUO97_04560 ENOG4105CSU acyl-Coa dehydrogenase AUO97_04570 ENOG41067S9 phage shock protein C, PspC AUO97_04575 ENOG4105W87 Cbs domain AUO97_04640 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin AUO97_04665 ENOG4105C26 Dehydrogenase AUO97_04675 ENOG4105C8Y Acetylornithine aminotransferase AUO97_04680 ENOG4105D82 Glutamate dehydrogenase AUO97_04685 ENOG4108IQI permease AUO97_04715 ENOG4107SKI cobyrinic Acid a,c-diamide synthase AUO97_04720 ENOG4105IPI Membrane AUO97_04725 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AUO97_04730 ENOG4105EM2 membrane AUO97_04735 ENOG4107QF7 multi-drug AUO97_04745 ENOG4105NF4 modulator of drug activity AUO97_04750 ENOG4105VRH Antibiotic biosynthesis monooxygenase AUO97_04760 ENOG4105CQB FAD linked oxidase domain protein AUO97_04765 ENOG4108JQ1 Dehydrogenase AUO97_04790 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AUO97_04795 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) AUO97_04800 ENOG4107IFA Lipase (EC 3.1.1.3) AUO97_04815 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) AUO97_04865 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) AUO97_04875 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AUO97_04880 ENOG4105KME endoribonuclease L-psp AUO97_04890 ENOG4108UQY Iron-storage protein AUO97_04895 ENOG4108YSG O-Antigen polymerase AUO97_04910 ENOG4105HA9 of methanol dehydrogenase type AUO97_04915 ENOG4108V0P LemA family AUO97_04925 ENOG4105BZ8 glutamate synthase AUO97_04930 ENOG4105CBC glutamate synthase AUO97_04950 ENOG4105E4G Type IV pilus AUO97_04975 ENOG4108JQC penicillin-binding protein 1A AUO97_04980 ENOG4105DHI Methyltransferase AUO97_04995 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) AUO97_05000 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AUO97_05005 ENOG4105CJN penicillin-binding protein AUO97_05020 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AUO97_05045 ENOG4108IQI permease AUO97_05110 ENOG4105C5H ABC transporter AUO97_05135 ENOG4105PDP Short chain dehydrogenase AUO97_05140 ENOG4105CHH sulfate transporter AUO97_05145 ENOG4105BZM domain protein AUO97_05150 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AUO97_05155 ENOG4105E0F Histidine kinase AUO97_05160 ENOG4105CYC Transferase AUO97_05190 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) AUO97_05220 ENOG41061CK Antibiotic biosynthesis monooxygenase AUO97_05235 ENOG4105CUV Homoserine Kinase AUO97_05290 ENOG4108UQN AraC family transcriptional regulator AUO97_05295 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain AUO97_05315 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AUO97_05320 ENOG4105KVH Transcriptional regulator AUO97_05350 ENOG4105KVH Transcriptional regulator AUO97_05375 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) AUO97_05400 ENOG4106NZI LysR family Transcriptional regulator AUO97_05405 ENOG4105D94 Major Facilitator Superfamily AUO97_05435 ENOG4105EUB pirin domain protein AUO97_05440 ENOG4105CHJ isochorismatase hydrolase AUO97_05450 ENOG4105C26 Dehydrogenase AUO97_05455 ENOG4108JPW Aminotransferase AUO97_05465 ENOG4105C85 amino acid AUO97_05475 ENOG4108UMN azlc family AUO97_05485 ENOG4108UUM single-stranded DNA-binding protein AUO97_05490 ENOG4107RDB Major Facilitator AUO97_05500 ENOG4105DWF phosphomethylpyrimidine kinase AUO97_05505 ENOG4105RA2 Membrane AUO97_05515 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AUO97_05520 ENOG4108WUH Transcriptional regulator, TetR family AUO97_05525 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AUO97_05530 ENOG4105BZU Histidine kinase AUO97_05540 ENOG4105C94 Transporter AUO97_05550 ENOG4107QN1 sodium solute AUO97_05555 ENOG41062QD Membrane AUO97_05560 ENOG4105BZU Histidine kinase AUO97_05575 ENOG4108UZX fmn reductase AUO97_05580 ENOG4105FBW Monooxygenase AUO97_05590 ENOG4108W2Y isochorismatase AUO97_05595 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AUO97_05605 ENOG4105D64 Mechanosensitive ion channel AUO97_05615 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase AUO97_05620 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AUO97_05640 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AUO97_05655 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AUO97_05670 ENOG4105E0K tonB-dependent siderophore receptor AUO97_05685 ENOG4107QSN dihydrolipoamide acetyltransferase AUO97_05690 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) AUO97_05695 ENOG41063SB peptidase AUO97_05710 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AUO97_05715 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AUO97_05720 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) AUO97_05740 ENOG4105D7Z glutathione synthase AUO97_05765 ENOG4105CGK Exodeoxyribonuclease III AUO97_05770 ENOG4105KUZ arsenate reductase AUO97_05785 ENOG4105BZU Histidine kinase AUO97_05790 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) AUO97_05820 ENOG41084YZ Hydrolase AUO97_05835 ENOG41061H0 Monooxygenase AUO97_05845 ENOG4108Z2U ureidoglycolate hydrolase AUO97_05850 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AUO97_05855 ENOG4105IPS esterase AUO97_05985 ENOG4105D6J arsenicaL-resistance protein AUO97_06025 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) AUO97_06085 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AUO97_06115 ENOG4105CHH sulfate transporter AUO97_06170 ENOG4105C0P Mg chelatase subunit ChlI AUO97_06175 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AUO97_06185 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AUO97_06195 ENOG41090KI Outer membrane porin AUO97_06200 ENOG4105F0N pyrophosphate phospho-hydrolase AUO97_06215 ENOG4105CEY Amp-dependent synthetase and ligase AUO97_06220 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AUO97_06225 ENOG41079KZ Major Facilitator Superfamily AUO97_06230 ENOG4105EN6 Membrane AUO97_06235 ENOG4105K5B UPF0225 protein AUO97_06240 ENOG4105EE5 Membrane protein terC AUO97_06245 ENOG4108URH decarboxylase AUO97_06250 ENOG4105C0R drug resistance transporter emrb qaca subfamily AUO97_06260 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AUO97_06275 ENOG4105CCT upf0313 protein AUO97_06295 ENOG4105CS1 NAD(P)H quinone oxidoreductase AUO97_06305 ENOG4105C6T cysteine synthase AUO97_06340 ENOG4105Y7M Transcriptional regulator, TetR family AUO97_06375 ENOG4105C79 DNA protecting protein DprA AUO97_06390 ENOG4108IND Tetr family transcriptional regulator AUO97_06395 ENOG4107RTG Major Facilitator superfamily AUO97_06405 ENOG4108V06 Glutathione peroxidase AUO97_06415 ENOG41090VV Protein of unknown function (DUF2846) AUO97_06450 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AUO97_06475 ENOG4105FDK ABC transporter AUO97_06480 ENOG4105FAV ABC, transporter AUO97_06490 ENOG4105EZR dyp-type peroxidase family protein AUO97_06495 ENOG4107R1I NAD-dependent malic enzyme AUO97_06520 ENOG4105EUB pirin domain protein AUO97_06540 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AUO97_06545 ENOG4106MP8 UPF0754 membrane protein AUO97_06550 ENOG4108VBZ doxx family AUO97_06555 ENOG4105DQR SNARE associated Golgi AUO97_06570 ENOG4107QJE Chromosome Partitioning Protein AUO97_06580 ENOG4107PSF BolA-like protein AUO97_06625 ENOG4105C1G acyl-Coa dehydrogenase AUO97_06630 ENOG4107RCI amp-dependent synthetase and ligase AUO97_06650 ENOG4105CSH Transporter AUO97_06655 ENOG4105E39 Enoyl-CoA hydratase AUO97_06660 ENOG4105E39 Enoyl-CoA hydratase AUO97_06665 ENOG4105C1G acyl-Coa dehydrogenase AUO97_06675 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AUO97_06680 ENOG4105C26 Dehydrogenase AUO97_06690 ENOG4105C85 amino acid AUO97_06695 ENOG4105C85 amino acid AUO97_06700 ENOG4105M4H endoribonuclease L-psp AUO97_06715 ENOG4105EW9 transcriptional regulator AsnC family AUO97_06740 ENOG4105D3G Pseudouridine synthase AUO97_06825 ENOG4108I0Z Aconitate hydratase AUO97_06830 ENOG4105BZN citrate synthase AUO97_06835 ENOG4105CR4 methylisocitrate lyase AUO97_06840 ENOG4105DRR Transcriptional regulator, GntR family AUO97_06845 ENOG4105CGF Aromatic amino acid aminotransferase AUO97_06850 ENOG4105CXG d-lactate dehydrogenase AUO97_06860 ENOG41073TP transcriptional regulator AUO97_06865 ENOG4105DAA L-lactate AUO97_06870 ENOG4107QKV phosphomannomutase AUO97_06875 ENOG4105CMR udp-glucose 4-epimerase AUO97_06885 ENOG4105C6Y Udp-glucose 6-dehydrogenase AUO97_06890 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AUO97_06895 ENOG4105D3Q Sugar transferase AUO97_06900 ENOG4108RYC glycosyltransferase AUO97_06905 ENOG4105CG5 Glycosyl transferase (Group 1 AUO97_06920 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) AUO97_06935 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AUO97_06940 ENOG4105J5G Transferase hexapeptide repeat containing protein AUO97_06945 ENOG4107R5Z Oxidoreductase domain protein AUO97_06950 ENOG4107QQG Dehydrogenase AUO97_06955 ENOG4105DAY polysaccharide export protein AUO97_06965 ENOG4105D75 Capsular exopolysaccharide family AUO97_06970 ENOG4108V1T peptidylprolyl cis-trans isomerase AUO97_06975 ENOG4108V1T peptidylprolyl cis-trans isomerase AUO97_06980 ENOG4105CJR Integral membrane protein (MviN AUO97_06985 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AUO97_06990 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AUO97_06995 ENOG4105HSS phospholipase C AUO97_07020 ENOG41062JF Transcriptional regulator AUO97_07035 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AUO97_07040 ENOG4105UBK short-chain dehydrogenase reductase AUO97_07055 ENOG4107QZM n-acetylglutamate synthase AUO97_07060 ENOG4105GVF (ABC) transporter AUO97_07065 ENOG4105GVF (ABC) transporter AUO97_07070 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AUO97_07075 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AUO97_07080 ENOG4108VM9 ABC, transporter AUO97_07085 ENOG4108R86 Transcriptional regulator AUO97_07090 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) AUO97_07100 ENOG4105DTN riboflavin biosynthesis protein ribF AUO97_07105 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AUO97_07115 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase AUO97_07155 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AUO97_07210 ENOG4105CVE Lytic murein transglycosylase AUO97_07215 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AUO97_07220 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AUO97_07235 ENOG4105DFU Cell wall formation (By similarity) AUO97_07245 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AUO97_07250 ENOG4105DU1 integral membrane protein, terc AUO97_07260 ENOG4106032 Glutathionylspermidine synthase AUO97_07270 ENOG4107QUY Guanine deaminase AUO97_07275 ENOG4108UGV hypoxanthine phosphoribosyltransferase AUO97_07285 ENOG4105T95 Thiol disulfide interChange protein AUO97_07290 ENOG4105PGM cation diffusion facilitator family transporter AUO97_07305 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AUO97_07320 ENOG4105VG0 50S ribosomal protein l34 AUO97_07330 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AUO97_07340 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AUO97_07350 ENOG4105DQR SNARE associated Golgi AUO97_07355 ENOG4105C5H ABC transporter AUO97_07360 ENOG4108821 RND type efflux pump AUO97_07365 ENOG4108821 RND type efflux pump AUO97_07370 ENOG4108821 RND type efflux pump AUO97_07380 ENOG4105D74 hydrolase AUO97_07385 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) AUO97_07390 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AUO97_07430 ENOG4105C8J )-transporter AUO97_07440 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AUO97_07470 ENOG4105C2W permease AUO97_07480 ENOG4108IG5 Transcriptional regulator AUO97_07485 ENOG4105DJY efflux transporter, rnd family, mfp subunit AUO97_07520 ENOG4105F27 Major Facilitator AUO97_07525 ENOG4105CV8 reductase AUO97_07530 ENOG4105HEI LysR family (Transcriptional regulator AUO97_07545 ENOG4105DQ4 alcohol dehydrogenase AUO97_07550 ENOG4108R3E Dna-3-methyladenine glycosylase i AUO97_07565 ENOG4105CEN a g-specific adenine glycosylase AUO97_07585 ENOG4108ZZ3 UPF0260 protein AUO97_07595 ENOG4105D1H recombination factor protein RarA AUO97_07600 ENOG4105S64 Formate nitrite transporter AUO97_07620 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AUO97_07625 ENOG4108RWI nicotinamidase AUO97_07630 ENOG4105C09 Bile acid AUO97_07635 ENOG4107QI1 Mate efflux family protein AUO97_07640 ENOG4105EWC Purine nucleoside phosphorylase AUO97_07660 ENOG4108RXX maleylacetoacetate isomerase AUO97_07670 ENOG4105C85 amino acid AUO97_07680 ENOG4105CKI cobalamin synthesis protein AUO97_07690 ENOG4105CZE histidine utilization repressor AUO97_07695 ENOG41090B9 response to stress AUO97_07710 ENOG4105C85 amino acid AUO97_07720 ENOG41088SP formiminoglutamate hydrolase AUO97_07740 ENOG4108NIW Leucine export protein LeuE AUO97_07760 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AUO97_07770 ENOG4108ZAI phosphatidylglycerophosphatase a AUO97_07775 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) AUO97_07790 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AUO97_07840 ENOG4105KHC sulfurtransferase AUO97_07855 ENOG4105BZU Histidine kinase AUO97_07860 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AUO97_07875 ENOG4107QJQ Mate efflux family protein AUO97_07880 ENOG4105CHM Aminotransferase AUO97_07885 ENOG4106BRA Membrane AUO97_07900 ENOG4105D9M gamma-glutamylcysteine synthetase AUO97_07940 ENOG4108A65 Transcriptional regulator AUO97_07945 ENOG4105CE1 Ferrous iron transport protein b AUO97_08050 ENOG4105KK6 nuclease AUO97_08185 ENOG4107QHF type ii secretion system protein e AUO97_08235 ENOG4107SKI cobyrinic Acid a,c-diamide synthase AUO97_08240 ENOG4105FA0 parb-like partition protein AUO97_08250 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AUO97_08255 ENOG4105KT5 UmuD protein AUO97_08280 ENOG4105DR5 peptidase AUO97_08460 ENOG4108K0D peptidase, M48 AUO97_08525 ENOG4105CHH sulfate transporter AUO97_08535 ENOG4105C0P Mg chelatase subunit ChlI AUO97_08550 ENOG4105BZU Histidine kinase AUO97_08560 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AUO97_08600 ENOG4108K5H permease YjgP YjgQ family protein AUO97_08605 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AUO97_08610 ENOG4105CN1 protease AUO97_08615 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AUO97_08620 ENOG4107TUY Histidine kinase AUO97_08630 ENOG41061WM D-Alanyl-D-Alanine AUO97_08640 ENOG4105D6E homoserine dehydrogenase AUO97_08645 ENOG4105T95 Thiol disulfide interChange protein AUO97_08650 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AUO97_08660 ENOG4105CE1 Ferrous iron transport protein b AUO97_08675 ENOG4105CNI cell division protein FtsW AUO97_08680 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) AUO97_08685 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters AUO97_08690 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) AUO97_08715 ENOG4108RNG Permease of the drug metabolite transporter AUO97_08720 ENOG4105DFG type I secretion outer membrane protein AUO97_08725 ENOG4108UTW Plays a role in the regulation of phosphate uptake AUO97_08740 ENOG4108HRK Histidine kinase AUO97_08745 ENOG4108NEV two component transcriptional regulator, LytTR family AUO97_08750 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) AUO97_08775 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS AUO97_08790 ENOG4105GVR general secretion pathway protein D AUO97_08795 ENOG4105TV9 FHA Domain-Containing protein AUO97_08800 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AUO97_08840 ENOG4105PM1 preprotein translocase subunit SecE AUO97_08845 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AUO97_08895 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) AUO97_08900 ENOG4105D3Y Na H antiporter AUO97_08915 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) AUO97_08930 ENOG4107ZXU DSBA oxidoreductase AUO97_08995 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase AUO97_09000 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AUO97_09030 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) AUO97_09040 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AUO97_09055 ENOG4105C2N RNA methyltransferase TrmH family group 3 AUO97_09065 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) AUO97_09080 ENOG4107QHF type ii secretion system protein e AUO97_09090 ENOG4107EJC Preprotein translocase subunit SecG AUO97_09110 ENOG4105CHV Transcription elongation factor NusA AUO97_09125 ENOG4105KJM monovalent cation h antiporter subunit g AUO97_09130 ENOG4105W4C monovalent cation H antiporter subunit F AUO97_09135 ENOG4105SC1 monovalent cation H antiporter subunit E AUO97_09140 ENOG4107R4Z monovalent cation h antiporter subunit d AUO97_09145 ENOG4108ZE9 Monovalent cation H antiporter subunit C AUO97_09150 ENOG4105D65 subunit l AUO97_09165 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AUO97_09185 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AUO97_09195 ENOG4105CSR polyphosphate kinase 2 AUO97_09205 ENOG4105DSY exodeoxyribonuclease V, gamma AUO97_09210 ENOG4107QKA exodeoxyribonuclease V beta AUO97_09215 ENOG4107QYX exodeoxyribonuclease v alpha AUO97_09235 ENOG4107QUT magnesium and cobalt transport protein CorA AUO97_09240 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) AUO97_09245 ENOG4105DVC DnaJ domain protein AUO97_09260 ENOG4105CKD glutathione-regulated potassium-efflux system protein AUO97_09265 ENOG4105C25 Primosomal protein n' AUO97_09270 ENOG4105D7Q type ii secretion system AUO97_09275 ENOG4108VAU general secretion pathway protein G AUO97_09285 ENOG4108Z7R Chaperone CsaA AUO97_09290 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) AUO97_09295 ENOG4108JU5 Magnesium and cobalt efflux protein AUO97_09300 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) AUO97_09310 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase AUO97_09320 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AUO97_09335 ENOG4105C5X domain protein AUO97_09340 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) AUO97_09350 ENOG4105BZ8 glutamate synthase AUO97_09385 ENOG4107T8P acyl-Coa dehydrogenase AUO97_09395 ENOG4107QI1 Mate efflux family protein AUO97_09405 ENOG4105CSA Coproporphyrinogen iii oxidase AUO97_09415 ENOG4105CBN LysR family transcriptional regulator AUO97_09435 ENOG4105C03 ribonuclease AUO97_09445 ENOG4105EI2 Pseudouridine synthase AUO97_09450 ENOG4107XGZ Hydrolase AUO97_09455 ENOG4105D29 Helix-turn-helix type 11 domain protein AUO97_09470 ENOG4108W5M transcriptional regulator AUO97_09485 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase AUO97_09500 ENOG4105DUM transcriptional regulator, lysR family AUO97_09525 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AUO97_09580 ENOG4105CK2 sodium dicarboxylate symporter AUO97_09590 ENOG4105D1S lipid A biosynthesis AUO97_09595 ENOG4105N14 lysine exporter protein LysE YggA AUO97_09600 ENOG4105C5H ABC transporter AUO97_09605 ENOG41069P5 Protein slyX homolog AUO97_09615 ENOG4105KVH Transcriptional regulator AUO97_09625 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AUO97_09640 ENOG4105C4R Atp-dependent dna helicase AUO97_09645 ENOG4105VFU Rna-binding protein AUO97_09665 ENOG4105CKD glutathione-regulated potassium-efflux system protein AUO97_09670 ENOG4105W0E 50S ribosomal protein L33 AUO97_09675 ENOG4105KDC 50s ribosomal protein l28 AUO97_09680 ENOG4107RGH Aldehyde dehydrogenase AUO97_09690 ENOG4105CIY formyltetrahydrofolate deformylase AUO97_09790 ENOG4105DWV Homoserine O-trans-acetylase AUO97_09800 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) AUO97_09810 ENOG4108ESX Receptor AUO97_09820 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AUO97_09840 ENOG4107GFK fumarate AUO97_09845 ENOG4108DNC Involved in acetate metabolism (By similarity) AUO97_09850 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AUO97_09855 ENOG4105C01 Dihydroxy-acid dehydratase AUO97_09860 ENOG4108UHU Aldolase AUO97_09865 ENOG4105C6Z Gluconate AUO97_09870 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AUO97_09875 ENOG4105C26 Dehydrogenase AUO97_09885 ENOG4106HB6 Alpha beta hydrolase AUO97_09900 ENOG4105CN1 protease AUO97_09915 ENOG4105WVQ Fe-S assembly protein IscX AUO97_09935 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) AUO97_09955 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AUO97_09975 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) AUO97_09990 ENOG4105CEY Amp-dependent synthetase and ligase AUO97_09995 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) AUO97_10005 ENOG4105C84 Histidine ammonia-lyase AUO97_10035 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AUO97_10045 ENOG4105C2D reductase AUO97_10050 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AUO97_10070 ENOG4105VW4 glutaredoxin 3 AUO97_10080 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) AUO97_10085 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) AUO97_10095 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH AUO97_10100 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AUO97_10105 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AUO97_10110 ENOG4105DJY efflux transporter, rnd family, mfp subunit AUO97_10140 ENOG4105C7K acetolactate synthase AUO97_10145 ENOG4108ZP8 Acetolactate synthase small subunit AUO97_10155 ENOG4105BZU Histidine kinase AUO97_10200 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) AUO97_10215 ENOG4105F8V Hydrolase, tatD family AUO97_10220 ENOG4107QM5 aconitate hydratase AUO97_10225 ENOG4105CUZ uba thif-type nad fad binding protein AUO97_10230 ENOG4107RSM transcriptional regulator AUO97_10240 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AUO97_10255 ENOG4106UX7 integral membrane protein AUO97_10260 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AUO97_10265 ENOG4105W8H transhydrogenase (subunit alpha AUO97_10270 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AUO97_10285 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) AUO97_10290 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AUO97_10295 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase AUO97_10300 ENOG4105BZU Histidine kinase AUO97_10305 ENOG4105C6T cysteine synthase AUO97_10320 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AUO97_10330 ENOG4105DXN mazG family AUO97_10335 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein AUO97_10340 ENOG4105DJ0 Poly(A) Polymerase AUO97_10345 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AUO97_10365 ENOG41080Z8 PHOSPHOCARRIER protein AUO97_10370 ENOG4105N42 UPF0307 protein AUO97_10375 ENOG4105CEY Amp-dependent synthetase and ligase AUO97_10395 ENOG4105CYM Glutathione S-transferase AUO97_10400 ENOG4105W39 Membrane AUO97_10420 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) AUO97_10450 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AUO97_10465 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) AUO97_10475 ENOG4105C9X ppx gppa phosphatase AUO97_10485 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AUO97_10490 ENOG4105II7 pyrroline-5-carboxylate reductase AUO97_10495 ENOG4108VIA integral membrane protein AUO97_10500 ENOG4105C2M dna polymerase I AUO97_10520 ENOG4107QHF type ii secretion system protein e AUO97_10525 ENOG4108ZHJ Organic hydroperoxide resistance protein AUO97_10530 ENOG4105K56 Transcriptional regulator AUO97_10600 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AUO97_10605 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) AUO97_10610 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AUO97_10620 ENOG4105CRQ synthase (Component I) AUO97_10665 ENOG4108Z0R Transferase AUO97_10670 ENOG41072GX Peptidase M22 Glycoprotease AUO97_10695 ENOG4105DJV ribulose-phosphate 3-epimerase AUO97_10700 ENOG4108HCJ Hydrolase AUO97_10710 ENOG4105E3B Multicopper oxidase AUO97_10730 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AUO97_10735 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) AUO97_10740 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) AUO97_10775 ENOG4105ETT transcriptional Regulator, LysR family AUO97_10780 ENOG4105C1G acyl-Coa dehydrogenase AUO97_10785 ENOG4107RGD Major Facilitator superfamily AUO97_10790 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F AUO97_10800 ENOG4107EFR Flavocytochrome c AUO97_10805 ENOG4106P55 Transcriptional regulator AUO97_10825 ENOG4106P55 Transcriptional regulator AUO97_10835 ENOG4105CH2 amidohydrolase AUO97_10855 ENOG4105ETT transcriptional Regulator, LysR family AUO97_10865 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) AUO97_10870 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) AUO97_10920 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AUO97_10930 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AUO97_10935 ENOG4107EXC regulatoR AUO97_10940 ENOG4105E0F Histidine kinase AUO97_10950 ENOG4105BZU Histidine kinase AUO97_10970 ENOG4105GKE subunit e AUO97_10975 ENOG4107QIZ NADH dehydrogenase AUO97_10980 ENOG4108IEH NADH dehydrogenase subunit g AUO97_10995 ENOG4107UFS subunit j AUO97_11005 ENOG4105D65 subunit l AUO97_11010 ENOG4105C8S subunit m AUO97_11035 ENOG4105DUM transcriptional regulator, lysR family AUO97_11040 ENOG4105DP0 ferredoxin-NADP reductase AUO97_11060 ENOG4105CBX hi0933 family AUO97_11065 ENOG4105K6H D-cysteine desulfhydrase AUO97_11095 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) AUO97_11105 ENOG4105D1F ATP-binding protein AUO97_11160 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) AUO97_11170 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY AUO97_11185 ENOG4105HF0 Membrane AUO97_11195 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) AUO97_11215 ENOG4106UW1 Major Facilitator superfamily AUO97_11220 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase AUO97_11225 ENOG4108K4C ec 3.1.3.12 AUO97_11230 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AUO97_11240 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AUO97_11245 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AUO97_11255 ENOG4105FE9 pseudouridine synthase AUO97_11260 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) AUO97_11265 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) AUO97_11270 ENOG4107RTD sua5 ycio yrdc ywlc family protein AUO97_11275 ENOG4108BPE -transporting atpase AUO97_11280 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein AUO97_11290 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AUO97_11295 ENOG4105CHR reductase AUO97_11305 ENOG4109066 lysm domain bon superfamily protein AUO97_11310 ENOG4105DWF phosphomethylpyrimidine kinase AUO97_11320 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AUO97_11350 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AUO97_11380 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) AUO97_11395 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AUO97_11400 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AUO97_11405 ENOG4105C34 Pseudouridine synthase AUO97_11410 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AUO97_11430 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AUO97_11450 ENOG4105EJC lysr family transcriptional regulator AUO97_11455 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AUO97_11460 ENOG4105C94 Transporter AUO97_11470 ENOG4105DVW rieske (2Fe-2S) AUO97_11475 ENOG4105C26 Dehydrogenase AUO97_11480 ENOG4105E3J oxidoreductase AUO97_11495 ENOG4105C4K Nad synthetase AUO97_11505 ENOG4105EUB pirin domain protein AUO97_11510 ENOG4108YXA Membrane AUO97_11555 ENOG4105KEG ribosomal-protein-alanine acetyltransferase AUO97_11565 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) AUO97_11570 ENOG4105C3M thioredoxin reductase AUO97_11575 ENOG4105CNU cell division protein FtsK AUO97_11595 ENOG4107QMS site-determining protein AUO97_11610 ENOG4106HNH Acyl-transferase AUO97_11615 ENOG4108ZG0 Ompa motb domain protein AUO97_11620 ENOG4105C4R Atp-dependent dna helicase AUO97_11630 ENOG4107QKV phosphomannomutase AUO97_11645 ENOG4105E7A Glutamine amidotransferase AUO97_11665 ENOG4105VDB UPF0125 protein AUO97_11675 ENOG41090R7 Ferric uptake AUO97_11680 ENOG4105CZX twitching motility protein AUO97_11685 ENOG4105CZX twitching motility protein AUO97_11690 ENOG4105DFA alanine racemase domain protein AUO97_11695 ENOG4105EYH Exonuclease AUO97_11700 ENOG4107RH8 nuclease SbcCD subunit D AUO97_11720 ENOG4105ECP epimerase AUO97_11725 ENOG4105MWK D-amino acid dehydrogenase, small subunit AUO97_11730 ENOG4105D52 delta-aminolevulinic acid dehydratase AUO97_11735 ENOG4108VUY thioesterase Superfamily protein AUO97_11740 ENOG4105CW7 secretion protein, HlyD family AUO97_11745 ENOG4105C0R drug resistance transporter emrb qaca subfamily AUO97_11750 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) AUO97_11795 ENOG4105C54 Major Facilitator superfamily AUO97_11800 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AUO97_11825 ENOG4105D5Q Arginine ornithine antiporter AUO97_11830 ENOG4107QK5 Homocysteine s-methyltransferase AUO97_11855 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) AUO97_11860 ENOG4105C94 Transporter AUO97_11865 ENOG4105C94 Transporter AUO97_11885 ENOG4105CKI cobalamin synthesis protein AUO97_11895 ENOG4108VWS Yaeq family AUO97_11905 ENOG4107BJW polysaccharide deacetylase AUO97_11910 ENOG4105CND Glycosyl transferase, family 2 AUO97_11920 ENOG4106YT9 Enoyl-CoA hydratase AUO97_11935 ENOG41069M3 Transcriptional regulator AUO97_11955 ENOG4105CHR reductase AUO97_11965 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase AUO97_11970 ENOG4105DJB Major Facilitator Superfamily AUO97_11980 ENOG4108MXF Alpha Beta Hydrolase AUO97_11985 ENOG4105CHR reductase AUO97_12000 ENOG4105C7K acetolactate synthase AUO97_12010 ENOG4105CSH Transporter AUO97_12015 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AUO97_12020 ENOG4105CSV Glutaminase AUO97_12025 ENOG4108R6W Transcriptional regulator, ARAC family AUO97_12030 ENOG4105EU0 Major facilitator Superfamily AUO97_12040 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) AUO97_12055 ENOG4108PZW LysR family Transcriptional regulator AUO97_12065 ENOG4105CSP Major Facilitator Superfamily AUO97_12080 ENOG4105C3R Methionine synthase AUO97_12085 ENOG4105CJ3 phosphate transporter AUO97_12100 ENOG4105E6M Sulphatase-modifying factor protein AUO97_12105 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) AUO97_12120 ENOG4107RNH Outer membrane receptor FepA AUO97_12140 ENOG4108UJV acyl-CoA thioesterase i AUO97_12145 ENOG4108I0Y (ABC) transporter AUO97_12150 ENOG4105CV6 ABC transporter, permease AUO97_12155 ENOG4107U91 Rhomboid family AUO97_12175 ENOG4105C5Q Transcriptional regulator AUO97_12185 ENOG4107QZF nitrite reductase NADPH large subunit AUO97_12190 ENOG4105VCQ rubredoxin AUO97_12210 ENOG4108MRJ AUO97_12220 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) AUO97_12235 ENOG4105D4T Citrate transporter AUO97_12245 ENOG4105C37 (CBS) domain AUO97_12255 ENOG4107RET Isocitrate lyase AUO97_12290 ENOG4105CQM Urea amidohydrolase subunit alpha AUO97_12300 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) AUO97_12315 ENOG4106H78 methyltransferase AUO97_12320 ENOG4105CJN penicillin-binding protein AUO97_12340 ENOG4105CSM endonuclease III AUO97_12345 ENOG4108R3D Electron transport complex AUO97_12350 ENOG4105D82 Glutamate dehydrogenase AUO97_12360 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AUO97_12385 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AUO97_12420 ENOG4107RAQ aminopeptidase AUO97_12425 ENOG4105D0A hydroxylase AUO97_12430 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AUO97_12450 ENOG4108ZUB Lysine exporter protein (Lyse ygga) AUO97_12455 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) AUO97_12465 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AUO97_12475 ENOG4105W4M Transport-associated protein AUO97_12485 ENOG4105E09 nadh pyrophosphatase AUO97_12495 ENOG4107RZZ dna polymerase iii epsilon subunit AUO97_12500 ENOG4105E9H Lytic Murein transglycosylase AUO97_12500 ENOG4105E9H Lytic Murein transglycosylase AUO97_12510 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component AUO97_12515 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component AUO97_12520 ENOG4108JQ5 ABC transporter AUO97_12540 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) AUO97_12565 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AUO97_12615 ENOG4105M4H endoribonuclease L-psp AUO97_12620 ENOG4105MWK D-amino acid dehydrogenase, small subunit AUO97_12625 ENOG4105CR8 Transcriptional regulator AUO97_12645 ENOG4105D01 (LipO)protein AUO97_12675 ENOG4105C85 amino acid AUO97_12685 ENOG4105CUB amino acid AUO97_12705 ENOG4105C26 Dehydrogenase AUO97_12725 ENOG4105C85 amino acid AUO97_12745 ENOG4107RGH Aldehyde dehydrogenase AUO97_12750 ENOG4108ZX5 transcriptional regulator AUO97_12755 ENOG4105DJP Membrane AUO97_12760 ENOG4105CTX dehydratase AUO97_12765 ENOG4105DJB Major Facilitator Superfamily AUO97_12770 ENOG4105EQX glucarate dehydratase AUO97_12780 ENOG4105CZJ Aldehyde dehydrogenase AUO97_12785 ENOG4105JXH GntR family transcriptional regulator AUO97_12800 ENOG4105NI3 Protein of unknown function (DUF3237) AUO97_12805 ENOG4105EPF Outer membrane porin AUO97_12810 ENOG4105C1G acyl-Coa dehydrogenase AUO97_12825 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase AUO97_12830 ENOG4108SC4 )-transporter AUO97_12845 ENOG4105E3J oxidoreductase AUO97_12855 ENOG4105D2S major facilitator superfamily AUO97_12860 ENOG4105EPF Outer membrane porin AUO97_12880 ENOG4107RN6 Monooxygenase AUO97_12890 ENOG4105JQZ Methyltransferase AUO97_12895 ENOG4105F95 Monooxygenase AUO97_12930 ENOG4105F95 Monooxygenase AUO97_12940 ENOG4105C7N Xanthine uracil vitamin C permease AUO97_12945 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) AUO97_12950 ENOG4105CPW cytochrome b561 AUO97_12960 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AUO97_12970 ENOG4105CFH Aspartokinase AUO97_13020 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) AUO97_13025 ENOG4105W7J DNA binding AUO97_13110 ENOG4107ZQ5 Phage-associated protein, HI1409 family AUO97_13135 ENOG41090AG Bacteriophage protein AUO97_13270 ENOG4105DFP Integrase AUO97_13280 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AUO97_13290 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis AUO97_13305 ENOG4105CPC Aldo Keto reductase AUO97_13310 ENOG4107RYR Transcriptional regulator, Crp Fnr family AUO97_13315 ENOG4108UKZ OsmC family AUO97_13330 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AUO97_13360 ENOG4105CD3 dihydroorotase AUO97_13365 ENOG4108ZG0 Ompa motb domain protein AUO97_13375 ENOG4108TGY Glutathione S-transferase AUO97_13380 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) AUO97_13390 ENOG4108K3A Glutathione S-transferase AUO97_13400 ENOG4108JU3 Alkyl hydroperoxide reductase AUO97_13410 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) AUO97_13420 ENOG4105D3R alkyl hydroperoxide reductase AUO97_13425 ENOG4105CQ7 ATP-dependent helicase AUO97_13440 ENOG4105D2S major facilitator superfamily AUO97_13445 ENOG4105DKK Benzoate AUO97_13450 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase AUO97_13455 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein AUO97_13460 ENOG4108UKV benzoate 1,2-dioxygenase AUO97_13465 ENOG4105FUY alpha subunit AUO97_13470 ENOG4108KB2 LysR family Transcriptional regulator AUO97_13525 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) AUO97_13560 ENOG410829K Lysine exporter protein (Lyse ygga) AUO97_13565 ENOG4105VEQ Cold shock protein AUO97_13575 ENOG4105II7 pyrroline-5-carboxylate reductase AUO97_13605 ENOG4107YPT transcriptional regulator AUO97_13640 ENOG4105C2X Arabinose 5-phosphate isomerase AUO97_13645 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase AUO97_13655 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA AUO97_13660 ENOG4108IUZ ABC transporter AUO97_13665 ENOG4105DFG type I secretion outer membrane protein AUO97_13705 ENOG4108Z4U Ferredoxin AUO97_13725 ENOG4107AQZ Membrane AUO97_13730 ENOG4105BZU Histidine kinase AUO97_13735 ENOG4105D1S lipid A biosynthesis AUO97_13740 ENOG4107QUT magnesium and cobalt transport protein CorA AUO97_13760 ENOG4105D2S major facilitator superfamily AUO97_13780 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) AUO97_13815 ENOG4108WAV Transcriptional regulator AUO97_13825 ENOG4105C5A transporter AUO97_13845 ENOG4108JIK carboxylase AUO97_13850 ENOG4107R4J Chloride channel AUO97_13870 ENOG4105R8C Transcriptional regulator AUO97_13880 ENOG4105E2A Dehydrogenase AUO97_13895 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AUO97_13900 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF AUO97_13915 ENOG4105MRR Transcriptional regulator (By similarity) AUO97_13925 ENOG4108HW3 (ABC) transporter AUO97_13955 ENOG4105E6M Sulphatase-modifying factor protein AUO97_14010 ENOG4105UYK outer membrane protein a AUO97_14020 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AUO97_14050 ENOG4105EMY transcriptional regulator AUO97_14060 ENOG4107Y2X deaminase AUO97_14065 ENOG4105DJ2 Major Facilitator Superfamily AUO97_14080 ENOG4105WPN DNA integration recombination invertion protein AUO97_14090 ENOG4108Z4X TRANSCRIPTIONal AUO97_14105 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AUO97_14125 ENOG4105MWK D-amino acid dehydrogenase, small subunit AUO97_14150 ENOG4105CZJ Aldehyde dehydrogenase AUO97_14155 ENOG4107QTZ amino acid AUO97_14160 ENOG4105EJQ L-serine dehydratase AUO97_14165 ENOG4105DXM phenylacetic acid degradation protein AUO97_14170 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit AUO97_14175 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit AUO97_14180 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit AUO97_14185 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit AUO97_14190 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AUO97_14195 ENOG4105E39 Enoyl-CoA hydratase AUO97_14200 ENOG4108UKI Enoyl-CoA hydratase AUO97_14205 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AUO97_14210 ENOG4105CHU acetyl-coa acetyltransferase AUO97_14215 ENOG4105DZS Phenylacetate-CoA ligase AUO97_14220 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein AUO97_14225 ENOG4108Z0R Transferase AUO97_14230 ENOG4107YAU phenylacetic acid degradation protein AUO97_14270 ENOG4107VGR Catalase AUO97_14275 ENOG4105CPW cytochrome b561 AUO97_14280 ENOG4105HEI LysR family (Transcriptional regulator AUO97_14290 ENOG4107HP6 Transcriptional regulator AUO97_14295 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase AUO97_14310 ENOG4105C4Y ABC transporter AUO97_14315 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AUO97_14320 ENOG4107RCV ABC transporter, permease AUO97_14330 ENOG4107STF Involved in phosphonate degradation (By similarity) AUO97_14335 ENOG4108KAZ Involved in phosphonate degradation (By similarity) AUO97_14340 ENOG4108NIW Leucine export protein LeuE AUO97_14355 ENOG4105CC0 LysR family Transcriptional regulator AUO97_14370 ENOG4105E39 Enoyl-CoA hydratase AUO97_14375 ENOG4107QX3 carboxylase AUO97_14380 ENOG4105C1G acyl-Coa dehydrogenase AUO97_14385 ENOG4105R8C Transcriptional regulator AUO97_14390 ENOG4105CEY Amp-dependent synthetase and ligase AUO97_14410 ENOG4105HEI LysR family (Transcriptional regulator AUO97_14455 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AUO97_14485 ENOG4105EW9 transcriptional regulator AsnC family AUO97_14495 ENOG4105BZU Histidine kinase AUO97_14500 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AUO97_14510 ENOG4105EAD ABC transporter AUO97_14515 ENOG4108HW4 amino acid AbC transporter AUO97_14525 ENOG4107RP9 extracellular solute-binding protein, family 3 AUO97_14530 ENOG4105CT1 (ABC) transporter AUO97_14535 ENOG4105EXG Transcriptional regulator AUO97_14545 ENOG4105C9B Cysteine desulfurase AUO97_14550 ENOG4105ESN nucleotide-binding protein AUO97_14555 ENOG4105D7W serine acetyltransferase AUO97_14565 ENOG4105CHR reductase AUO97_14570 ENOG4105CBN LysR family transcriptional regulator AUO97_14575 ENOG4105CYM Glutathione S-transferase AUO97_14580 ENOG4108SHQ Glutathione S-transferase AUO97_14585 ENOG4105CMU LysR family (Transcriptional regulator AUO97_14590 ENOG4105VAW lrga family AUO97_14595 ENOG41067MG lrgb family AUO97_14600 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AUO97_14615 ENOG4105DXI Major Facilitator superfamily AUO97_14625 ENOG4105ETT transcriptional Regulator, LysR family AUO97_14635 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase AUO97_14640 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) AUO97_14655 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase AUO97_14660 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AUO97_14675 ENOG4108K70 Transcriptional regulator AUO97_14680 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AUO97_14685 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AUO97_14690 ENOG4105C4M (Ubiquinol oxidase) subunit I AUO97_14715 ENOG4105C54 Major Facilitator superfamily AUO97_14725 ENOG4106FTQ Taurine ABC transporter, periplasmic AUO97_14730 ENOG4108IY8 ABC, transporter AUO97_14735 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AUO97_14740 ENOG4105E2B Taurine dioxygenase AUO97_14750 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease AUO97_14760 ENOG4105CBN LysR family transcriptional regulator AUO97_14770 ENOG4105CPN adenine deaminase AUO97_14785 ENOG41082YX Transcriptional regulator, arsr family AUO97_14790 ENOG4105D6J arsenicaL-resistance protein AUO97_14795 ENOG4108KB2 LysR family Transcriptional regulator AUO97_14810 ENOG4108JU3 Alkyl hydroperoxide reductase AUO97_14835 ENOG4105C0B DNA polymerase III (alpha subunit) AUO97_14845 ENOG4105CK2 sodium dicarboxylate symporter AUO97_14850 ENOG4105CHM Aminotransferase AUO97_14860 ENOG4108V06 Glutathione peroxidase AUO97_14865 ENOG4105E7U AraC family transcriptional regulator AUO97_14895 ENOG4105ZED uncharacterized protein ygaH AUO97_14900 ENOG4108UMN azlc family AUO97_14925 ENOG4105C3G gtp-binding protein AUO97_14930 ENOG4108UMI ABC transporter, permease AUO97_14935 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AUO97_14940 ENOG4105D01 (LipO)protein AUO97_14945 ENOG4105D01 (LipO)protein AUO97_14960 ENOG4107T8P acyl-Coa dehydrogenase AUO97_14975 ENOG4105EAD ABC transporter AUO97_14980 ENOG4105DRP amino acid AbC transporter AUO97_14985 ENOG4105CDA abc transporter atp-binding protein AUO97_14995 ENOG4105EW9 transcriptional regulator AsnC family AUO97_15010 ENOG41067SE Tetr family transcriptional regulator AUO97_15030 ENOG4105CC0 LysR family Transcriptional regulator AUO97_15040 ENOG4105ETS cytosine purines uracil thiamine allantoin AUO97_15050 ENOG4108IPJ Membrane AUO97_15080 ENOG4105GQR Chaperone AUO97_15085 ENOG4105X0I Fimbrial AUO97_15105 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) AUO97_15110 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) AUO97_15130 ENOG4108HWY Beta-lactamase AUO97_15155 ENOG4105CV1 Transketolase (EC 2.2.1.1) AUO97_15165 ENOG4108YYC ycei family AUO97_15175 ENOG4108T58 Mg2 transport protein CorA AUO97_15190 ENOG4105YGK Pfam:UPF0157 AUO97_15195 ENOG4105C26 Dehydrogenase AUO97_15200 ENOG4105EW9 transcriptional regulator AsnC family AUO97_15205 ENOG4105CK7 Sodium proline symporter AUO97_15210 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) AUO97_15220 ENOG4108ZX5 transcriptional regulator AUO97_15230 ENOG4105BZ1 (ABC) transporter AUO97_15235 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme AUO97_15240 ENOG4105XPP Protein of unknown function (DUF1275) AUO97_15250 ENOG41080HT Transcriptional regulator, arsr family AUO97_15260 ENOG4105EZE Cupin 4 family protein AUO97_15265 ENOG4108UHJ MAF-like protein AUO97_15285 ENOG4105D2N Aldolase AUO97_15290 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) AUO97_15295 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) AUO97_15300 ENOG4105EHM Aminoglycoside phosphotransferase AUO97_15305 ENOG4108S0S Nucleotidyl transferase AUO97_15315 ENOG4107QJE Chromosome Partitioning Protein AUO97_15320 ENOG4105FA0 parb-like partition protein AUO97_15335 ENOG4105BZ1 (ABC) transporter AUO97_15340 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) AUO97_15350 ENOG4107QRG dna polymerase iii AUO97_15360 ENOG4105F8V Hydrolase, tatD family AUO97_15385 ENOG4108RTD type II secretion system protein K AUO97_15405 ENOG4108Z6B deaminase AUO97_15420 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) AUO97_15425 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) AUO97_15445 ENOG4107RN6 Monooxygenase AUO97_15455 ENOG4105D6Z AFG1 family ATPase AUO97_15530 ENOG4105CDU Replicative dna helicase AUO97_15615 ENOG4105EFC phage portal protein HK97 family AUO97_15725 ENOG4107QP3 malate synthase g AUO97_15735 ENOG4105SG9 biopolymer transport protein, ExbD AUO97_15770 ENOG4105DGW oligopeptidase A AUO97_15780 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AUO97_15800 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase AUO97_15815 ENOG4105K4T epimerase AUO97_15820 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) AUO97_15840 ENOG4108JA2 transcriptioN-repair coupling factor AUO97_15850 ENOG4105F8J Adenylate Guanylate cyclase AUO97_15855 ENOG4108ZIT Ferredoxin, 2FE-2S AUO97_15870 ENOG4108Z4V iron-sulfur cluster assembly AUO97_15875 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins AUO97_15885 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family AUO97_15900 ENOG4105K70 DNA-binding protein AUO97_15910 ENOG4105E7U AraC family transcriptional regulator AUO97_15915 ENOG4105EEF Alkane 1-monooxygenase AUO97_15920 ENOG4105C1G acyl-Coa dehydrogenase AUO97_15925 ENOG4105C1G acyl-Coa dehydrogenase AUO97_15940 ENOG4108Z66 YbaK ebsC protein AUO97_15955 ENOG4105C0R drug resistance transporter emrb qaca subfamily AUO97_15960 ENOG4105DUU IucA IucC family protein AUO97_15965 ENOG4105DJU Siderophore biosynthesis protein AUO97_15975 ENOG4105JSC dimethylmenaquinone methyltransferase AUO97_16020 ENOG4108YZT Adenosylcobinamide kinase AUO97_16025 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) AUO97_16030 ENOG4107TB6 phosphoglycerate mutase AUO97_16045 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AUO97_16050 ENOG4107TSN permease AUO97_16070 ENOG4105CNM Receptor AUO97_16075 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AUO97_16090 ENOG4105CJ1 ABC, transporter AUO97_16095 ENOG4107QWP ABC-2 type transporter AUO97_16100 ENOG4107QWP ABC-2 type transporter AUO97_16125 ENOG4105K59 histidine triad (HIT) protein AUO97_16155 ENOG4105F2W methyltransferase AUO97_16165 ENOG4105C28 cystathionine AUO97_16180 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) AUO97_16185 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) AUO97_16210 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AUO97_16220 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AUO97_16225 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) AUO97_16235 ENOG4105BZU Histidine kinase AUO97_16250 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) AUO97_16255 ENOG4107R0V Pyruvate dehydrogenase AUO97_16260 ENOG4105CPP Dehydrogenase, E1 component AUO97_16275 ENOG4105CHR reductase AUO97_16285 ENOG4105FFC UPF0187 protein AUO97_16295 ENOG4107S76 domain protein AUO97_16305 ENOG4108VCT Sulfite exporter TauE/SafE AUO97_16320 ENOG4105UEI Transcriptional Regulator AraC Family AUO97_16325 ENOG4105KVH Transcriptional regulator AUO97_16330 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AUO97_16340 ENOG4105FDP GntR family transcriptional regulator AUO97_16355 ENOG4106FTQ Taurine ABC transporter, periplasmic AUO97_16360 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AUO97_16380 ENOG4105CSH Transporter AUO97_16390 ENOG4108IJ0 Aspartate ammonia-lyase AUO97_16405 ENOG4107YNJ LysR family Transcriptional regulator AUO97_16415 ENOG4105CHU acetyl-coa acetyltransferase AUO97_16420 ENOG4105CRW Short chain fatty acid transporter AUO97_16435 ENOG4108M0I Transcriptional regulator AUO97_16455 ENOG4108IND Tetr family transcriptional regulator AUO97_16465 ENOG4105CY2 Citrate transporter AUO97_16470 ENOG4105DTD Dehydrogenase AUO97_16475 ENOG4105CF7 AraC family transcriptional regulator AUO97_16480 ENOG4105D2S major facilitator superfamily AUO97_16490 ENOG4105CHR reductase AUO97_16535 ENOG4105BZS acriflavin resistance protein AUO97_16540 ENOG4105C1P efflux transporter, rnd family, mfp subunit AUO97_16545 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AUO97_16550 ENOG4105E0F Histidine kinase AUO97_16560 ENOG4108821 RND type efflux pump AUO97_16565 ENOG4108R6W Transcriptional regulator, ARAC family AUO97_16615 ENOG4105M03 Domain of unknown function (DUF955) AUO97_16655 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) AUO97_16730 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AUO97_16750 ENOG4105E0A ABC, transporter AUO97_16755 ENOG4105EHG Permease protein AUO97_16765 ENOG4105DQ4 alcohol dehydrogenase AUO97_16770 ENOG4105CF7 AraC family transcriptional regulator AUO97_16775 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AUO97_16785 ENOG4105EXW epimerase dehydratase AUO97_16790 ENOG4105DDW LysR family Transcriptional regulator AUO97_16800 ENOG4105C01 Dihydroxy-acid dehydratase AUO97_16805 ENOG4105CZJ Aldehyde dehydrogenase AUO97_16820 ENOG4105CW7 secretion protein, HlyD family AUO97_16835 ENOG4106KR7 LysR family Transcriptional regulator AUO97_16850 ENOG4105FDP GntR family transcriptional regulator AUO97_16930 ENOG4105CEY Amp-dependent synthetase and ligase AUO97_16940 ENOG4105CSU acyl-Coa dehydrogenase AUO97_16950 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr AUO97_16955 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AUO97_16960 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AUO97_16965 ENOG4108PTX LysR family Transcriptional regulator AUO97_16970 ENOG4107Z3H Transcriptional regulator, TetR family AUO97_16995 ENOG4108Z6Z Transcriptional regulator AUO97_17005 ENOG4105NAE bifunctional deaminase-reductase domain protein AUO97_17015 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AUO97_17030 ENOG4105CZJ Aldehyde dehydrogenase AUO97_17050 ENOG4107EJG GntR family transcriptional regulator AUO97_17060 ENOG4108KB2 LysR family Transcriptional regulator AUO97_17065 ENOG4105DTQ mandelate racemase muconate lactonizing AUO97_17070 ENOG4105NN7 muconolactone delta-isomerase AUO97_17080 ENOG4107QP7 CoA-transferase subunit A AUO97_17085 ENOG4107QNJ CoA-transferase subunit B AUO97_17090 ENOG4105CHU acetyl-coa acetyltransferase AUO97_17095 ENOG4105F2Z 3-oxoadipate enol-lactonase AUO97_17105 ENOG4105C26 Dehydrogenase AUO97_17115 ENOG4105F11 amine oxidase AUO97_17135 ENOG4105CHR reductase AUO97_17145 ENOG4105FUY alpha subunit AUO97_17165 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AUO97_17175 ENOG4105DNH Major Facilitator AUO97_17200 ENOG4105C1G acyl-Coa dehydrogenase AUO97_17205 ENOG4108PTX LysR family Transcriptional regulator AUO97_17210 ENOG4107HP6 Transcriptional regulator AUO97_17225 ENOG4105MD1 YeeE YedE family protein AUO97_17235 ENOG4105DZG Dehydrogenase AUO97_17240 ENOG4105TW1 Carbohydrate-selective porin OprB AUO97_17245 ENOG4106JPM 3-dehydroshikimate dehydratase AUO97_17250 ENOG4105FF2 Type I DHQase AUO97_17255 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha AUO97_17260 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta AUO97_17265 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase AUO97_17270 ENOG4105D2S major facilitator superfamily AUO97_17275 ENOG4105F2Z 3-oxoadipate enol-lactonase AUO97_17280 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase AUO97_17285 ENOG4105CHU acetyl-coa acetyltransferase AUO97_17290 ENOG4107QNJ CoA-transferase subunit B AUO97_17295 ENOG4107QP7 CoA-transferase subunit A AUO97_17305 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) AUO97_17310 ENOG4107VMU Membrane AUO97_17355 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AUO97_17370 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AUO97_17380 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AUO97_17385 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) AUO97_17415 ENOG4105C7B Threonine dehydratase AUO97_17425 ENOG4105CZN Potassium uptake protein AUO97_17430 ENOG4105HDD phospholipase AUO97_17440 ENOG4105E0K tonB-dependent siderophore receptor AUO97_17455 ENOG4105PV3 Inner membrane protein yqiJ AUO97_17465 ENOG4105C4M (Ubiquinol oxidase) subunit I AUO97_17470 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AUO97_17490 ENOG41068P6 UPF0319 protein AUO97_17500 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AUO97_17530 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AUO97_17535 ENOG4105C8Y Acetylornithine aminotransferase AUO97_17540 ENOG4105M2J Glutaredoxin AUO97_17550 ENOG4105CC0 LysR family Transcriptional regulator AUO97_17555 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AUO97_17560 ENOG4105CWM branched-chain amino acid transport system II carrier protein AUO97_17585 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AUO97_17590 ENOG4105DE4 1-phosphofructokinase AUO97_17595 ENOG4105DM4 PTS System AUO97_17610 ENOG4105BZU Histidine kinase AUO97_17620 ENOG4105D8V Glucose sorbosone dehydrogenase AUO97_17625 ENOG4108RAV Conserved protein AUO97_17630 ENOG4105CHH sulfate transporter AUO97_17645 ENOG4105C85 amino acid AUO97_17655 ENOG4105F7P transcriptional regulator AsnC family AUO97_17680 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 AUO97_17685 ENOG4105VEJ Heat shock protein AUO97_17695 ENOG4105Y3E Modulates RecA activity (By similarity) AUO97_17710 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AUO97_17730 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AUO97_17735 ENOG4105DZP Membrane-associated zinc metalloprotease AUO97_17745 ENOG4105KNE Phosphatidate cytidylyltransferase AUO97_17750 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) AUO97_17770 ENOG4105CUX Signal transduction histidine kinase AUO97_17775 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AUO97_17835 ENOG4105CMR udp-glucose 4-epimerase AUO97_17840 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) AUO97_17860 ENOG4105T38 integral membrane protein AUO97_17865 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AUO97_17875 ENOG4105CVM Molybdenum cofactor synthesis domain protein AUO97_17880 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AUO97_17915 ENOG4108IFG nitrite reductase, (NAD(P)H) AUO97_17920 ENOG4107QZF nitrite reductase NADPH large subunit AUO97_17930 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AUO97_17950 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein AUO97_17955 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AUO97_17965 ENOG4105D8G Major Facilitator superfamily AUO97_17980 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AUO97_18040 ENOG4105UPP uncharacterized protein ydcA AUO97_18190 ENOG4105WXW Antirepressor AUO97_18335 ENOG4105CBC glutamate synthase AUO97_18365 ENOG4105C0A alcohol dehydrogenase AUO97_18375 ENOG4105HSS phospholipase C AUO97_18380 ENOG4107QMP dna polymerase iii subunits gamma and tau AUO97_18405 ENOG4105CHR reductase AUO97_18410 ENOG4105CHU acetyl-coa acetyltransferase AUO97_18420 ENOG4105C5Q Transcriptional regulator AUO97_18425 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AUO97_18430 ENOG4108NIW Leucine export protein LeuE AUO97_18435 ENOG4105EW9 transcriptional regulator AsnC family AUO97_18440 ENOG4105DKK Benzoate AUO97_18450 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic AUO97_18465 ENOG41081QV Universal stress protein AUO97_18470 ENOG4105C5H ABC transporter AUO97_18485 ENOG4105CNM Receptor AUO97_18515 ENOG4105CUY Mechanosensitive ion channel AUO97_18525 ENOG4105R8C Transcriptional regulator AUO97_18540 ENOG4105EW9 transcriptional regulator AsnC family AUO97_18545 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) AUO97_18570 ENOG4108D1K outer membrane usher protein AUO97_18585 ENOG4105CD8 aminopeptidase N AUO97_18610 ENOG4107QUV Domain protein AUO97_18615 ENOG4105C0A alcohol dehydrogenase AUO97_18625 ENOG4107RR1 TRANSCRIPTIONal AUO97_18635 ENOG4107R55 ethanolamine transporter AUO97_18640 ENOG4105CPD ethanolamine ammonia-lyase AUO97_18645 ENOG4107FQ9 ethanolamine ammonia-lyase AUO97_18650 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AUO97_18675 ENOG4108RCM Nitroreductase AUO97_18680 ENOG4108TZV Membrane AUO97_18685 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) AUO97_18695 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) AUO97_18700 ENOG4105K8N protein family UPF0079, ATPase AUO97_18735 ENOG4105DZ2 Transcriptional regulator AUO97_18750 ENOG4105F27 Major Facilitator AUO97_18755 ENOG4105EYW Ion transport protein AUO97_18765 ENOG4107QIJ Aconitate hydratase 2 AUO97_18785 ENOG4105CFU surface antigen AUO97_18790 ENOG4107S74 Lysophospholipid transporter LplT AUO97_18805 ENOG4105CFQ glutamine synthetase AUO97_18810 ENOG4105EEX Two component transcriptional regulator (Winged helix family AUO97_18815 ENOG4105C08 Histidine kinase AUO97_18820 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) AUO97_18825 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AUO97_18830 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AUO97_18840 ENOG4105KRF dihydroneopterin aldolase AUO97_18850 ENOG4105D06 uba thif-type nad fad binding protein AUO97_18855 ENOG4108MEJ flavin reductase domain protein AUO97_18865 ENOG4105C1G acyl-Coa dehydrogenase AUO97_18880 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AUO97_18895 ENOG4105CC0 LysR family Transcriptional regulator AUO97_18915 ENOG4105DEN Luciferase family AUO97_18925 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD AUO97_18930 ENOG4105CND Glycosyl transferase, family 2 AUO97_18935 ENOG4107BJW polysaccharide deacetylase AUO97_18960 ENOG4105E2S oxidase) subunit II AUO97_18965 ENOG4105BZ9 Cytochrome C oxidase, subunit I AUO97_18970 ENOG4105CCU oxidase (Subunit III) AUO97_18975 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) AUO97_19000 ENOG4105CDU Replicative dna helicase AUO97_19005 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AUO97_19055 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) AUO97_19060 ENOG4105DC1 bifunctional purine biosynthesis protein purh AUO97_19065 ENOG4105C12 Phosphoribosylglycinamide synthetase AUO97_19075 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AUO97_19080 ENOG4108UMI ABC transporter, permease AUO97_19085 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AUO97_19095 ENOG4105CK2 sodium dicarboxylate symporter AUO97_19140 ENOG4105DY2 Paraquat-inducible protein b AUO97_19145 ENOG4105F1S paraquat-inducible protein a AUO97_19180 ENOG4105CSH Transporter AUO97_19230 ENOG4105JXH GntR family transcriptional regulator AUO97_19240 ENOG4105D6U Sodium Glutamate Symporter