locus-tag	class	description
EAE94_00010	COG0592	DNA-directed DNA polymerase activity
EAE94_00020	COG0187	DNA topoisomerase II activity
EAE94_00030	COG0586	Pfam SNARE associated Golgi protein
EAE94_00035	COG0488	(ABC) transporter
EAE94_00060	COG0596	Alpha beta hydrolase
EAE94_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EAE94_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EAE94_00115	COG0733	neurotransmitter:sodium symporter activity
EAE94_00155	COG2233	PERMEase
EAE94_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE94_00205	COG2814	Major facilitator Superfamily
EAE94_00210	COG0656	L-ascorbic acid biosynthetic process
EAE94_00215	COG0583	DNA-binding transcription factor activity
EAE94_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE94_00235	COG1064	alcohol dehydrogenase
EAE94_00240	COG2818	Glycosylase
EAE94_00255	COG1194	a g-specific adenine glycosylase
EAE94_00275	COG2983	Belongs to the UPF0260 family
EAE94_00280	COG2133	pyrroloquinoline quinone binding
EAE94_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EAE94_00290	COG2116	formate transmembrane transporter activity
EAE94_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE94_00315	COG1335	isochorismatase
EAE94_00320	COG0385	Bile acid
EAE94_00325	COG0534	Mate efflux family protein
EAE94_00330	COG1683	Conserved Protein
EAE94_00350	COG0625	glutathione transferase activity
EAE94_00360	COG1113	amino acid transport
EAE94_00370	COG0523	cobalamin synthesis protein
EAE94_00380	COG2188	Transcriptional regulator
EAE94_00410	COG0010	Belongs to the arginase family
EAE94_00430	COG1280	lysine exporter protein (LysE YggA)
EAE94_00450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EAE94_00460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EAE94_00465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EAE94_00515	COG0753	catalase activity
EAE94_00565	COG0534	Mate efflux family protein
EAE94_00570	COG0436	Aminotransferase
EAE94_00575	COG2733	membrane
EAE94_00590	COG2918	glutathione biosynthetic process
EAE94_00605	COG1388	LysM domain
EAE94_00605	COG1705	Flagellar rod assembly protein muramidase FlgJ
EAE94_00640	COG3150	esterase
EAE94_00650	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EAE94_00660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE94_00670	COG2233	PERMEase
EAE94_00675	COG2351	hydroxyisourate hydrolase activity
EAE94_00710	COG3706	GGDEF domain
EAE94_00725	COG1393	Belongs to the ArsC family
EAE94_00730	COG0708	Exodeoxyribonuclease III
EAE94_00755	COG0189	ligase activity
EAE94_00775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EAE94_00785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAE94_00800	COG4942	peptidase
EAE94_00810	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAE94_00820	COG2119	membrane
EAE94_00825	COG4774	siderophore transport
EAE94_00830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE94_00830	COG0426	domain, Protein
EAE94_00855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EAE94_00875	COG1902	pentaerythritol trinitrate reductase activity
EAE94_00880	COG1519	Transferase
EAE94_00890	COG0668	transmembrane transport
EAE94_00900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAE94_00905	COG1335	isochorismatase
EAE94_00910	COG1522	sequence-specific DNA binding
EAE94_00935	COG0784	Response regulator, receiver
EAE94_00935	COG2198	Histidine kinase
EAE94_00935	COG2205	protein histidine kinase activity
EAE94_00940	COG3162	membrane
EAE94_00945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAE94_00955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE94_00970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EAE94_00975	COG1309	transcriptional regulator
EAE94_00995	COG0351	phosphomethylpyrimidine kinase
EAE94_00995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EAE94_00995	COG0352	thiamine-phosphate diphosphorylase activity
EAE94_01005	COG2814	Major facilitator Superfamily
EAE94_01020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EAE94_01030	COG1113	amino acid transport
EAE94_01040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAE94_01045	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_01055	COG1335	isochorismatase
EAE94_01095	COG2814	Major facilitator Superfamily
EAE94_01100	COG0583	DNA-binding transcription factor activity
EAE94_01145	COG1733	regulation of RNA biosynthetic process
EAE94_01175	COG1733	regulation of RNA biosynthetic process
EAE94_01185	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAE94_01205	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EAE94_01210	COG2207	Transcriptional regulator
EAE94_01265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAE94_01280	COG2329	Antibiotic biosynthesis monooxygenase
EAE94_01310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EAE94_01340	COG0427	acetyl-CoA hydrolase
EAE94_01365	COG0659	secondary active sulfate transmembrane transporter activity
EAE94_01370	COG4221	oxidoreductase activity
EAE94_01395	COG0488	(ABC) transporter
EAE94_01460	COG0833	amino acid
EAE94_01505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAE94_01510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EAE94_01525	COG2226	methyltransferase
EAE94_01575	COG0069	glutamate synthase activity
EAE94_01575	COG0070	glutamate synthase
EAE94_01575	COG0067	glutamate synthase
EAE94_01580	COG0493	'glutamate synthase
EAE94_01590	COG1704	LemA family
EAE94_01595	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EAE94_01605	COG4969	Belongs to the N-Me-Phe pilin family
EAE94_01610	COG3307	-O-antigen
EAE94_01630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAE94_01645	COG0194	GDP metabolic process
EAE94_01695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EAE94_01715	COG5380	lipid catabolic process
EAE94_01720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EAE94_01745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAE94_01750	COG0277	FAD linked oxidase domain protein
EAE94_01760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EAE94_01765	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAE94_01780	COG1289	transmembrane transporter activity
EAE94_01790	COG0628	permease
EAE94_01795	COG1192	Involved in chromosome partitioning
EAE94_01825	COG0833	amino acid
EAE94_01830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAE94_01835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAE94_01845	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_01885	COG0583	DNA-binding transcription factor activity
EAE94_01935	COG0517	IMP dehydrogenase activity
EAE94_01940	COG1983	PspC domain protein
EAE94_01950	COG1960	acyl-CoA dehydrogenase activity
EAE94_01965	COG0408	coproporphyrinogen oxidase activity
EAE94_01985	COG0513	Belongs to the DEAD box helicase family
EAE94_01990	COG1127	ABC transporter
EAE94_01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAE94_02005	COG2854	intermembrane phospholipid transfer
EAE94_02015	COG0598	Magnesium transport protein CorA
EAE94_02025	COG0494	nUDIX hydrolase
EAE94_02030	COG1040	competence protein
EAE94_02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EAE94_02055	COG1946	Acyl-CoA thioesterase
EAE94_02060	COG1301	dicarboxylic acid transport
EAE94_02075	COG1959	2 iron, 2 sulfur cluster binding
EAE94_02080	COG1017	nitric oxide dioxygenase activity
EAE94_02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE94_02090	COG0433	COG0433 Predicted ATPase
EAE94_02095	COG0626	cystathionine gamma-synthase activity
EAE94_02250	COG1960	acyl-CoA dehydrogenase activity
EAE94_02255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EAE94_02285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EAE94_02290	COG0339	signal peptide processing
EAE94_02295	COG0557	exoribonuclease II activity
EAE94_02340	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAE94_02345	COG2169	Transcriptional regulator
EAE94_02350	COG0697	spore germination
EAE94_02355	COG1295	ribonuclease BN
EAE94_02390	COG1702	phosphate starvation-inducible protein PhoH
EAE94_02400	COG0739	heme binding
EAE94_02400	COG0741	lytic transglycosylase activity
EAE94_02400	COG1196	nuclear chromosome segregation
EAE94_02430	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EAE94_02435	COG1183	phosphatidylcholine synthase activity
EAE94_02480	COG1960	acyl-CoA dehydrogenase activity
EAE94_02485	COG1309	transcriptional regulator
EAE94_02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EAE94_02505	COG1960	acyl-CoA dehydrogenase activity
EAE94_02525	COG2969	positive regulation of protein catabolic process
EAE94_02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EAE94_02545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EAE94_02550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EAE94_02555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAE94_02575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAE94_02585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAE94_02600	COG2199	diguanylate cyclase activity
EAE94_02660	COG1607	acyl-coa hydrolase
EAE94_02695	COG3013	Belongs to the UPF0304 family
EAE94_02775	COG2205	protein histidine kinase activity
EAE94_02790	COG2132	Multicopper oxidase
EAE94_02815	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE94_02865	COG0582	viral genome integration into host DNA
EAE94_02890	COG2350	Protein conserved in bacteria
EAE94_02900	COG0613	PHP domain protein
EAE94_02905	COG3781	membrane
EAE94_02915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAE94_02920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAE94_02930	COG1862	Preprotein translocase
EAE94_02960	COG0582	viral genome integration into host DNA
EAE94_02985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAE94_03005	COG2205	protein histidine kinase activity
EAE94_03010	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EAE94_03030	COG0726	polysaccharide deacetylase
EAE94_03035	COG0463	Glycosyl transferase, family 2
EAE94_03040	COG0438	transferase activity, transferring glycosyl groups
EAE94_03055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EAE94_03105	COG1960	acyl-CoA dehydrogenase activity
EAE94_03110	COG1960	acyl-CoA dehydrogenase activity
EAE94_03120	COG2205	protein histidine kinase activity
EAE94_03125	COG0745	RESPONSE REGULATOR receiver
EAE94_03130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EAE94_03150	COG2096	Adenosyltransferase
EAE94_03155	COG4206	TonB-dependent receptor
EAE94_03200	COG0285	dihydrofolate synthase activity
EAE94_03220	COG0450	alkyl hydroperoxide reductase
EAE94_03235	COG0477	Major facilitator Superfamily
EAE94_03240	COG1272	protein, Hemolysin III
EAE94_03250	COG2153	protein acetylation
EAE94_03270	COG0183	Belongs to the thiolase family
EAE94_03275	COG2207	Transcriptional regulator
EAE94_03295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAE94_03315	COG0183	Belongs to the thiolase family
EAE94_03335	COG1690	Belongs to the RtcB family
EAE94_03340	COG0833	amino acid
EAE94_03350	COG2233	PERMEase
EAE94_03355	COG1217	gtp-binding protein TYPA
EAE94_03380	COG2094	Belongs to the DNA glycosylase MPG family
EAE94_03385	COG4772	TonB-dependent receptor
EAE94_03390	COG1902	pentaerythritol trinitrate reductase activity
EAE94_03405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAE94_03410	COG0354	folic acid binding
EAE94_03420	COG3189	MarR family transcriptional regulator
EAE94_03425	COG2824	Alkylphosphonate utilization operon protein PhnA
EAE94_03430	COG3422	double-strand break repair
EAE94_03470	COG0840	transmembrane signaling receptor activity
EAE94_03490	COG5510	response to toxic substance
EAE94_03500	COG2832	Protein of unknown function (DUF454)
EAE94_03505	COG1376	ErfK ybiS ycfS ynhG family protein
EAE94_03545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EAE94_03555	COG1289	transmembrane transporter activity
EAE94_03560	COG2814	Major facilitator Superfamily
EAE94_03580	COG1115	amino acid carrier protein
EAE94_03585	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAE94_03590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAE94_03595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EAE94_03600	COG3590	peptidase
EAE94_03625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAE94_03635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAE94_03640	COG1077	Cell shape determining protein MreB Mrl
EAE94_03645	COG1792	Involved in formation and maintenance of cell shape
EAE94_03650	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EAE94_03655	COG0424	maF-like protein
EAE94_03660	COG1530	ribonuclease E activity
EAE94_03670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE94_03680	COG0560	Phosphoserine phosphatase
EAE94_03690	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAE94_03715	COG2207	Transcriptional regulator
EAE94_03735	COG1113	amino acid transport
EAE94_03740	COG2828	Protein conserved in bacteria
EAE94_03745	COG0142	geranyltranstransferase activity
EAE94_03750	COG2315	Protein conserved in bacteria
EAE94_03765	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAE94_03785	COG2194	sulfuric ester hydrolase activity
EAE94_03790	COG0745	RESPONSE REGULATOR receiver
EAE94_03795	COG0642	Histidine kinase
EAE94_03805	COG0004	ammonium transporteR
EAE94_03815	COG0583	DNA-binding transcription factor activity
EAE94_03835	COG0525	valine-tRNA ligase activity
EAE94_03845	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_03855	COG0393	Putative heavy-metal-binding
EAE94_03860	COG0393	Putative heavy-metal-binding
EAE94_03865	COG1538	Outer membrane efflux protein
EAE94_03875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE94_03880	COG0671	phosphoesterase, PA-phosphatase related
EAE94_03910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EAE94_03925	COG1648	precorrin-2 dehydrogenase activity
EAE94_03925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EAE94_03930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EAE94_03935	COG1733	regulation of RNA biosynthetic process
EAE94_03945	COG0531	amino acid
EAE94_03960	COG0321	lipoyl(octanoyl) transferase activity
EAE94_03965	COG2921	Belongs to the UPF0250 family
EAE94_04005	COG2009	succinate dehydrogenase
EAE94_04010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EAE94_04015	COG1053	succinate dehydrogenase
EAE94_04020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAE94_04045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAE94_04065	COG2354	Protein conserved in bacteria
EAE94_04070	COG2321	neutral zinc metallopeptidase
EAE94_04090	COG2843	Capsule synthesis protein
EAE94_04105	COG0589	response to stress
EAE94_04115	COG0251	oxidation-reduction process
EAE94_04120	COG1309	transcriptional regulator
EAE94_04135	COG0505	Belongs to the CarA family
EAE94_04160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAE94_04165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EAE94_04215	COG0477	Major facilitator Superfamily
EAE94_04220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EAE94_04235	COG1597	lipid kinase activity
EAE94_04240	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EAE94_04260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAE94_04265	COG0584	glycerophosphoryl diester phosphodiesterase
EAE94_04285	COG0741	lytic transglycosylase activity
EAE94_04310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAE94_04325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE94_04335	COG3811	Belongs to the UPF0386 family
EAE94_04395	COG0778	Nitroreductase
EAE94_04410	COG1929	Belongs to the glycerate kinase type-1 family
EAE94_04415	COG0243	molybdopterin cofactor binding
EAE94_04420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EAE94_04425	COG3339	Conserved Protein
EAE94_04435	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EAE94_04450	COG1113	amino acid transport
EAE94_04460	COG0019	diaminopimelate decarboxylase activity
EAE94_04470	COG1280	lysine exporter protein (LysE YggA)
EAE94_04475	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EAE94_04505	COG0463	Glycosyl transferase, family 2
EAE94_04525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE94_04555	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAE94_04560	COG1136	(ABC) transporter
EAE94_04565	COG0658	competence protein
EAE94_04565	COG2333	competence protein COMEC
EAE94_04575	COG0616	signal peptide processing
EAE94_04575	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EAE94_04580	COG0596	Alpha beta hydrolase
EAE94_04585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAE94_04595	COG0628	permease
EAE94_04630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAE94_04650	COG0823	Involved in the tonB-independent uptake of proteins
EAE94_04670	COG0824	Thioesterase
EAE94_04675	COG1473	amidohydrolase
EAE94_04695	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAE94_04695	COG0047	phosphoribosylformylglycinamidine synthase activity
EAE94_04725	COG1169	isochorismate synthase
EAE94_04730	COG1535	isochorismatase
EAE94_04730	COG3433	isochorismatase activity
EAE94_04735	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_04740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE94_04745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE94_04745	COG2226	methyltransferase
EAE94_04745	COG3433	isochorismatase activity
EAE94_04750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE94_04755	COG1021	2,3-dihydroxybenzoate-AMP ligase
EAE94_04760	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EAE94_04765	COG0019	diaminopimelate decarboxylase activity
EAE94_04785	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EAE94_04790	COG4774	siderophore transport
EAE94_04805	COG0534	Mate efflux family protein
EAE94_04815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE94_04890	COG1024	Enoyl-CoA hydratase
EAE94_04895	COG1056	cytidyltransferase-related domain
EAE94_04895	COG1051	belongs to the nudix hydrolase family
EAE94_04905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAE94_04920	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EAE94_04935	COG4625	pathogenesis
EAE94_04940	COG0583	DNA-binding transcription factor activity
EAE94_04945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAE94_04950	COG4208	sulfate ABC transporter
EAE94_04955	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EAE94_04965	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAE94_04970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAE94_04975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAE94_04995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAE94_05005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAE94_05015	COG0681	Belongs to the peptidase S26 family
EAE94_05030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EAE94_05040	COG1381	Involved in DNA repair and RecF pathway recombination
EAE94_05045	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EAE94_05055	COG4221	oxidoreductase activity
EAE94_05085	COG0443	Heat shock 70 kDa protein
EAE94_05095	COG0436	Aminotransferase
EAE94_05115	COG0556	nucleotide-excision repair
EAE94_05170	COG2070	2-Nitropropane dioxygenase
EAE94_05200	COG1215	transferase activity, transferring glycosyl groups
EAE94_05215	COG0415	Belongs to the DNA photolyase family
EAE94_05225	COG1252	NADH dehydrogenase
EAE94_05230	COG1686	Belongs to the peptidase S11 family
EAE94_05245	COG1187	pseudouridine synthase activity
EAE94_05270	COG0477	Major facilitator Superfamily
EAE94_05275	COG0583	DNA-binding transcription factor activity
EAE94_05280	COG1823	symporter activity
EAE94_05290	COG0612	Peptidase, M16
EAE94_05315	COG0352	thiamine-phosphate diphosphorylase activity
EAE94_05350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE94_05360	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAE94_05375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAE94_05380	COG0076	glutamate decarboxylase activity
EAE94_05390	COG1522	sequence-specific DNA binding
EAE94_05395	COG3961	Belongs to the TPP enzyme family
EAE94_05400	COG1113	amino acid transport
EAE94_05405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAE94_05410	COG0573	inorganic phosphate transmembrane transporter activity
EAE94_05420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EAE94_05425	COG0616	signal peptide processing
EAE94_05460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAE94_05465	COG1686	Belongs to the peptidase S11 family
EAE94_05490	COG0583	DNA-binding transcription factor activity
EAE94_05495	COG1067	ATP-dependent peptidase activity
EAE94_05520	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EAE94_05540	COG1966	Carbon starvation protein
EAE94_05545	COG2879	small protein
EAE94_05585	COG1335	isochorismatase
EAE94_05590	COG0583	DNA-binding transcription factor activity
EAE94_05605	COG0596	Alpha beta hydrolase
EAE94_05615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAE94_05655	COG1741	Belongs to the pirin family
EAE94_05665	COG2964	Protein conserved in bacteria
EAE94_05680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE94_05685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE94_05690	COG4605	iron ion homeostasis
EAE94_05695	COG4604	ABC transporter, ATP-binding protein
EAE94_05700	COG4607	ABC-type enterochelin transport system periplasmic component
EAE94_05705	COG4774	siderophore transport
EAE94_05715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE94_05720	COG1021	2,3-dihydroxybenzoate-AMP ligase
EAE94_05725	COG3433	isochorismatase activity
EAE94_05725	COG1535	isochorismatase
EAE94_05740	COG1132	(ABC) transporter
EAE94_05745	COG1132	(ABC) transporter
EAE94_05750	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EAE94_05775	COG3739	integral membrane protein
EAE94_05795	COG0302	gtp cyclohydrolase
EAE94_05805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EAE94_05835	COG0308	aminopeptidase N
EAE94_05840	COG0512	Glutamine amidotransferase of anthranilate synthase
EAE94_05855	COG0174	glutamine synthetase
EAE94_05865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EAE94_05900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EAE94_05905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAE94_05910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAE94_05930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EAE94_05935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EAE94_05940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EAE94_05955	COG1960	acyl-CoA dehydrogenase activity
EAE94_05960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EAE94_05965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAE94_05975	COG2223	nitrite transmembrane transporter activity
EAE94_05985	COG0024	Methionine aminopeptidase
EAE94_05990	COG0052	Belongs to the universal ribosomal protein uS2 family
EAE94_06005	COG2207	Transcriptional regulator
EAE94_06030	COG2951	lytic endotransglycosylase activity
EAE94_06035	COG0772	Belongs to the SEDS family
EAE94_06050	COG0842	Transport permease protein
EAE94_06055	COG1131	(ABC) transporter
EAE94_06100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE94_06115	COG4215	(ABC) transporter
EAE94_06120	COG4160	amino acid transport
EAE94_06125	COG4598	ABC transporter
EAE94_06135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE94_06140	COG0826	peptidase U32
EAE94_06145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE94_06160	COG1720	tRNA m6t6A37 methyltransferase activity
EAE94_06170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAE94_06185	COG0642	Histidine kinase
EAE94_06195	COG0494	nUDIX hydrolase
EAE94_06205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAE94_06210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EAE94_06215	COG3139	Protein of unknown function (DUF1315)
EAE94_06220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAE94_06230	COG1301	dicarboxylic acid transport
EAE94_06235	COG1960	acyl-CoA dehydrogenase activity
EAE94_06240	COG2819	hydrolase of the alpha beta superfamily
EAE94_06250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EAE94_06260	COG2195	Cleaves the N-terminal amino acid of tripeptides
EAE94_06280	COG1690	Belongs to the RtcB family
EAE94_06285	COG1234	tRNA 3'-trailer cleavage
EAE94_06290	COG4650	regulator
EAE94_06320	COG2363	Small membrane protein
EAE94_06340	COG0513	Belongs to the DEAD box helicase family
EAE94_06350	COG0778	Nitroreductase
EAE94_06380	COG1286	toxin biosynthetic process
EAE94_06405	COG4783	chaperone-mediated protein folding
EAE94_06410	COG1610	YqeY-like protein
EAE94_06440	COG0515	serine threonine protein kinase
EAE94_06440	COG2815	serine threonine protein kinase
EAE94_06510	COG3111	PFAM Bacterial OB fold (BOF) protein
EAE94_06535	COG3243	poly(R)-hydroxyalkanoic acid synthase
EAE94_06540	COG0786	glutamate:sodium symporter activity
EAE94_06550	COG2186	Transcriptional regulator
EAE94_06600	COG0477	Major facilitator Superfamily
EAE94_06605	COG1051	belongs to the nudix hydrolase family
EAE94_06635	COG2995	paraquat-inducible protein a
EAE94_06640	COG3008	intermembrane lipid transfer
EAE94_06640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAE94_06655	COG1794	racemase activity, acting on amino acids and derivatives
EAE94_06685	COG1301	dicarboxylic acid transport
EAE94_06695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAE94_06700	COG2011	ABC-type metal ion transport system permease component
EAE94_06705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAE94_06710	COG1464	Belongs to the NlpA lipoprotein family
EAE94_06715	COG0151	Belongs to the GarS family
EAE94_06720	COG0138	bifunctional purine biosynthesis protein purh
EAE94_06725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EAE94_06755	COG2308	Evidence 4 Homologs of previously reported genes of
EAE94_06765	COG1305	Transglutaminase-like
EAE94_06775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAE94_06780	COG0305	Participates in initiation and elongation during chromosome replication
EAE94_06805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EAE94_06815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EAE94_06820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EAE94_06845	COG0726	polysaccharide deacetylase
EAE94_06845	COG1649	PFAM Uncharacterised BCR, COG1649
EAE94_06850	COG1215	transferase activity, transferring glycosyl groups
EAE94_06855	COG3658	cytochrome
EAE94_06865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE94_06885	COG0583	DNA-binding transcription factor activity
EAE94_06915	COG1960	acyl-CoA dehydrogenase activity
EAE94_06920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAE94_06925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE94_06940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAE94_06950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EAE94_06955	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EAE94_06960	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EAE94_06965	COG2205	protein histidine kinase activity
EAE94_06970	COG0745	RESPONSE REGULATOR receiver
EAE94_06975	COG0174	glutamine synthetase
EAE94_06995	COG0729	surface antigen
EAE94_07025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAE94_07030	COG2814	Major facilitator Superfamily
EAE94_07045	COG0583	DNA-binding transcription factor activity
EAE94_07060	COG1187	pseudouridine synthase activity
EAE94_07080	COG0802	atpase or kinase
EAE94_07085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EAE94_07095	COG1923	regulation of RNA biosynthetic process
EAE94_07100	COG0697	spore germination
EAE94_07125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAE94_07130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAE94_07130	COG0519	Catalyzes the synthesis of GMP from XMP
EAE94_07135	COG4302	ethanolamine ammonia-lyase activity
EAE94_07140	COG4303	Ethanolamine ammonia lyase large subunit
EAE94_07145	COG0531	amino acid
EAE94_07165	COG1454	alcohol dehydrogenase
EAE94_07170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAE94_07195	COG0308	aminopeptidase N
EAE94_07235	COG1605	Chorismate mutase
EAE94_07250	COG1309	transcriptional regulator
EAE94_07260	COG0668	transmembrane transport
EAE94_07290	COG4773	Receptor
EAE94_07310	COG0488	(ABC) transporter
EAE94_07315	COG0589	response to stress
EAE94_07330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EAE94_07340	COG3135	benzoate transporter
EAE94_07345	COG1522	sequence-specific DNA binding
EAE94_07355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAE94_07360	COG0583	DNA-binding transcription factor activity
EAE94_07370	COG0183	Belongs to the thiolase family
EAE94_07380	COG2030	dehydratase
EAE94_07385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAE94_07400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAE94_07410	COG0824	Thioesterase
EAE94_07415	COG1454	alcohol dehydrogenase
EAE94_07425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EAE94_07445	COG0069	glutamate synthase activity
EAE94_07590	COG3617	BRO family, N-terminal domain
EAE94_07625	COG5410	chromosome segregation
EAE94_07735	COG1598	PFAM Uncharacterised protein family UPF0150
EAE94_07800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAE94_07815	COG2814	Major facilitator Superfamily
EAE94_07830	COG0511	ligase activity, forming carbon-carbon bonds
EAE94_07850	COG1116	anion transmembrane transporter activity
EAE94_07850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAE94_07855	COG0745	RESPONSE REGULATOR receiver
EAE94_07865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAE94_07865	COG2146	nitrite reductase [NAD(P)H] activity
EAE94_07870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAE94_07875	COG0243	molybdopterin cofactor binding
EAE94_07885	COG0243	molybdopterin cofactor binding
EAE94_07890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EAE94_07905	COG0315	cyclic pyranopterin monophosphate synthase activity
EAE94_07905	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAE94_07910	COG0303	'Molybdopterin
EAE94_07920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE94_07925	COG0697	spore germination
EAE94_07945	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EAE94_07950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAE94_08010	COG2204	response regulator
EAE94_08015	COG3852	Histidine kinase
EAE94_08040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EAE94_08045	COG0575	Belongs to the CDS family
EAE94_08060	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAE94_08080	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAE94_08095	COG2137	regulation of response to DNA damage stimulus
EAE94_08105	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EAE94_08110	COG1011	Hydrolase
EAE94_08135	COG1522	sequence-specific DNA binding
EAE94_08145	COG1113	amino acid transport
EAE94_08160	COG0659	secondary active sulfate transmembrane transporter activity
EAE94_08165	COG2135	peptidase activity
EAE94_08180	COG3300	MHYT domain
EAE94_08180	COG5001	Diguanylate cyclase
EAE94_08195	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EAE94_08195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAE94_08195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAE94_08200	COG1105	Belongs to the carbohydrate kinase PfkB family
EAE94_08205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAE94_08205	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE94_08235	COG0024	Methionine aminopeptidase
EAE94_08240	COG0583	DNA-binding transcription factor activity
EAE94_08250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EAE94_08255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAE94_08260	COG0517	IMP dehydrogenase activity
EAE94_08260	COG0516	GMP reductase activity
EAE94_08285	COG0552	protein localization to endoplasmic reticulum
EAE94_08295	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EAE94_08310	COG4890	Cyd operon protein YbgT
EAE94_08315	COG1294	oxidase, subunit
EAE94_08330	COG1585	Membrane protein implicated in regulation of membrane protease activity
EAE94_08340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE94_08345	COG4774	siderophore transport
EAE94_08360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAE94_08365	COG0569	domain protein
EAE94_08370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAE94_08400	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EAE94_08405	COG0542	response to heat
EAE94_08430	COG1902	pentaerythritol trinitrate reductase activity
EAE94_08430	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAE94_08475	COG2323	membrane
EAE94_08480	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EAE94_08490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EAE94_08495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAE94_08500	COG0183	Belongs to the thiolase family
EAE94_08505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EAE94_08510	COG0596	Alpha beta hydrolase
EAE94_08515	COG2271	Major facilitator Superfamily
EAE94_08520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAE94_08525	COG3485	protocatechuate 3,4-dioxygenase
EAE94_08530	COG3485	protocatechuate 3,4-dioxygenase
EAE94_08535	COG0710	3-dehydroquinate dehydratase activity
EAE94_08540	COG3420	alginic acid biosynthetic process
EAE94_08545	COG3659	wide pore channel activity
EAE94_08550	COG4993	Dehydrogenase
EAE94_08560	COG2391	methyltransferase activity
EAE94_08575	COG1414	Transcriptional regulator
EAE94_08580	COG0583	DNA-binding transcription factor activity
EAE94_08585	COG1960	acyl-CoA dehydrogenase activity
EAE94_08610	COG2814	Major facilitator Superfamily
EAE94_08620	COG0154	amidase activity
EAE94_08640	COG4638	Rieske (2fe-2S)
EAE94_08650	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_08660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE94_08670	COG3733	amine oxidase
EAE94_08680	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_08690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAE94_08695	COG0183	Belongs to the thiolase family
EAE94_08700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAE94_08705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EAE94_08715	COG4829	muconolactone delta-isomerase
EAE94_08720	COG4948	Mandelate Racemase Muconate Lactonizing
EAE94_08725	COG0583	DNA-binding transcription factor activity
EAE94_08735	COG2186	Transcriptional regulator
EAE94_08755	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_08770	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAE94_08770	COG1902	pentaerythritol trinitrate reductase activity
EAE94_08780	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EAE94_08790	COG0789	Transcriptional regulator
EAE94_08815	COG1309	transcriptional regulator
EAE94_08820	COG0583	DNA-binding transcription factor activity
EAE94_08825	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_08830	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_08835	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_08845	COG1960	acyl-CoA dehydrogenase activity
EAE94_08855	COG0318	PFAM AMP-dependent synthetase and ligase
EAE94_08945	COG2188	Transcriptional regulator
EAE94_08960	COG0583	DNA-binding transcription factor activity
EAE94_08975	COG1566	PFAM secretion protein HlyD family protein
EAE94_08990	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_08995	COG0129	dihydroxy-acid dehydratase activity
EAE94_09005	COG0583	DNA-binding transcription factor activity
EAE94_09010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAE94_09020	COG2084	Dehydrogenase
EAE94_09025	COG2207	Transcriptional regulator
EAE94_09030	COG1064	alcohol dehydrogenase
EAE94_09040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE94_09045	COG1120	ATPase activity
EAE94_09140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EAE94_09180	COG2856	Zn peptidase
EAE94_09235	COG2207	Transcriptional regulator
EAE94_09250	COG2205	protein histidine kinase activity
EAE94_09255	COG0745	RESPONSE REGULATOR receiver
EAE94_09260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE94_09265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE94_09355	COG3539	Fimbrial protein
EAE94_09380	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EAE94_09390	COG0753	catalase activity
EAE94_09405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAE94_09470	COG3433	isochorismatase activity
EAE94_09470	COG1535	isochorismatase
EAE94_09475	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_09480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EAE94_09485	COG4149	molybdate abc transporter
EAE94_09490	COG0725	ABC transporter, periplasmic molybdate-binding protein
EAE94_09500	COG4638	Rieske (2fe-2S)
EAE94_09505	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EAE94_09510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE94_09510	COG0543	2 iron, 2 sulfur cluster binding
EAE94_09525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE94_09535	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_09550	COG2207	Transcriptional regulator
EAE94_09555	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_09560	COG2610	gluconate transmembrane transporter activity
EAE94_09570	COG1309	transcriptional regulator
EAE94_09590	COG0583	DNA-binding transcription factor activity
EAE94_09605	COG2031	fatty acid transporter
EAE94_09610	COG0183	Belongs to the thiolase family
EAE94_09615	COG0583	DNA-binding transcription factor activity
EAE94_09620	COG0583	DNA-binding transcription factor activity
EAE94_09635	COG1027	Aspartate ammonia-lyase
EAE94_09645	COG0477	Major facilitator Superfamily
EAE94_09665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAE94_09670	COG4521	taurine ABC transporter
EAE94_09685	COG2188	Transcriptional regulator
EAE94_09695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EAE94_09700	COG1733	regulation of RNA biosynthetic process
EAE94_09705	COG2207	Transcriptional regulator
EAE94_09705	COG3708	Transcriptional regulator
EAE94_09720	COG0730	response to heat
EAE94_09730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAE94_09730	COG3453	Protein conserved in bacteria
EAE94_09740	COG3781	membrane
EAE94_09745	COG1063	alcohol dehydrogenase
EAE94_09755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAE94_09760	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAE94_09765	COG0022	dehydrogenase e1 component
EAE94_09770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EAE94_09775	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EAE94_09790	COG3706	GGDEF domain
EAE94_09805	COG0133	tryptophan synthase activity
EAE94_09815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAE94_09845	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EAE94_09850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EAE94_09875	COG2226	methyltransferase
EAE94_09930	COG0842	Transport permease protein
EAE94_09935	COG0842	Transport permease protein
EAE94_09940	COG1131	(ABC) transporter
EAE94_09955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAE94_09960	COG4773	Receptor
EAE94_09980	COG0730	response to heat
EAE94_09985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAE94_10000	COG0406	alpha-ribazole phosphatase activity
EAE94_10005	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EAE94_10055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAE94_10065	COG4264	IucA IucC family
EAE94_10070	COG4264	IucA IucC family
EAE94_10075	COG2814	Major facilitator Superfamily
EAE94_10090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAE94_10105	COG1960	acyl-CoA dehydrogenase activity
EAE94_10110	COG1960	acyl-CoA dehydrogenase activity
EAE94_10115	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE94_10120	COG2207	Transcriptional regulator
EAE94_10125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAE94_10130	COG0776	regulation of translation
EAE94_10155	COG0822	iron-sulfur transferase activity
EAE94_10160	COG0316	Belongs to the HesB IscA family
EAE94_10190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAE94_10210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAE94_10215	COG0702	epimerase
EAE94_10250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE94_10260	COG0339	signal peptide processing
EAE94_10310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EAE94_10420	COG4695	Portal protein
EAE94_10575	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAE94_10605	COG0776	regulation of translation
EAE94_10670	COG0084	hydrolase, TatD family'
EAE94_10690	COG1663	tetraacyldisaccharide 4'-kinase activity
EAE94_10695	COG1132	(ABC) transporter
EAE94_10705	COG0811	peptide transport
EAE94_10710	COG1475	DNA binding
EAE94_10715	COG1192	Involved in chromosome partitioning
EAE94_10725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EAE94_10740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAE94_10745	COG0191	fructose-bisphosphate aldolase activity
EAE94_10765	COG0424	maF-like protein
EAE94_10770	COG2850	peptidyl-arginine hydroxylation
EAE94_10780	COG0640	Transcriptional regulator
EAE94_10790	COG3619	membrane
EAE94_10795	COG3122	Protein conserved in bacteria
EAE94_10800	COG1132	(ABC) transporter
EAE94_10820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EAE94_10825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAE94_10835	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAE94_10835	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAE94_10835	COG0506	proline dehydrogenase activity
EAE94_10840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EAE94_10855	COG3698	Phosphodiester glycosidase
EAE94_10865	COG2353	YceI-like domain
EAE94_10875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAE94_10920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAE94_10920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EAE94_10945	COG3539	Fimbrial protein
EAE94_10950	COG3121	Chaperone
EAE94_10980	COG0697	spore germination
EAE94_10990	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EAE94_11000	COG0583	DNA-binding transcription factor activity
EAE94_11020	COG1309	transcriptional regulator
EAE94_11035	COG1522	sequence-specific DNA binding
EAE94_11045	COG1126	abc transporter atp-binding protein
EAE94_11050	COG0765	amino acid transport
EAE94_11055	COG0765	amino acid transport
EAE94_11085	COG1464	Belongs to the NlpA lipoprotein family
EAE94_11095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAE94_11100	COG2011	ABC-type metal ion transport system permease component
EAE94_11105	COG0012	GTP binding
EAE94_11130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EAE94_11170	COG0386	Belongs to the glutathione peroxidase family
EAE94_11180	COG0436	Aminotransferase
EAE94_11185	COG1301	dicarboxylic acid transport
EAE94_11220	COG3634	alkyl hydroperoxide reductase activity
EAE94_11235	COG0583	DNA-binding transcription factor activity
EAE94_11240	COG0798	PFAM Bile acid sodium symporter
EAE94_11245	COG0640	Transcriptional regulator
EAE94_11260	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EAE94_11270	COG0583	DNA-binding transcription factor activity
EAE94_11280	COG1953	Uracil, thiamine, allantoin
EAE94_11290	COG2175	clavaminate synthase activity
EAE94_11295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAE94_11300	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EAE94_11305	COG4521	taurine ABC transporter
EAE94_11315	COG0477	Major facilitator Superfamily
EAE94_11340	COG1271	oxidase subunit
EAE94_11345	COG1294	oxidase, subunit
EAE94_11355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE94_11375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EAE94_11395	COG3052	prosthetic group binding
EAE94_11400	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EAE94_11410	COG0583	DNA-binding transcription factor activity
EAE94_11420	COG2814	Major facilitator Superfamily
EAE94_11435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE94_11440	COG1346	cytolysis
EAE94_11450	COG0583	DNA-binding transcription factor activity
EAE94_11455	COG0625	glutathione transferase activity
EAE94_11460	COG0625	glutathione transferase activity
EAE94_11465	COG0583	DNA-binding transcription factor activity
EAE94_11480	COG1045	serine acetyltransferase
EAE94_11485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAE94_11490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAE94_11515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE94_11520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE94_11530	COG0765	amino acid transport
EAE94_11535	COG0765	amino acid transport
EAE94_11555	COG2205	protein histidine kinase activity
EAE94_11555	COG0784	Response regulator, receiver
EAE94_11595	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_11640	COG0583	DNA-binding transcription factor activity
EAE94_11660	COG0318	PFAM AMP-dependent synthetase and ligase
EAE94_11665	COG1309	transcriptional regulator
EAE94_11670	COG1960	acyl-CoA dehydrogenase activity
EAE94_11675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EAE94_11680	COG1024	Enoyl-CoA hydratase
EAE94_11685	COG4770	biotin carboxylase activity
EAE94_11695	COG0583	DNA-binding transcription factor activity
EAE94_11715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE94_11720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EAE94_11735	COG3842	ATPase activity
EAE94_11740	COG1840	ABC-type Fe3 transport system, periplasmic component
EAE94_11755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE94_11760	COG1414	Transcriptional regulator
EAE94_11770	COG0583	DNA-binding transcription factor activity
EAE94_11775	COG3038	cytochrome b561
EAE94_11780	COG0753	catalase activity
EAE94_11815	COG2050	protein possibly involved in aromatic compounds catabolism
EAE94_11825	COG3327	negative regulation of DNA-templated transcription, initiation
EAE94_11830	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EAE94_11835	COG0183	Belongs to the thiolase family
EAE94_11840	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAE94_11845	COG1024	Enoyl-CoA hydratase
EAE94_11850	COG1024	Enoyl-CoA hydratase
EAE94_11855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE94_11860	COG2151	metal-sulfur cluster biosynthetic enzyme
EAE94_11865	COG3396	Phenylacetate-CoA oxygenase
EAE94_11870	COG3460	Phenylacetate-CoA oxygenase
EAE94_11875	COG3396	Phenylacetate-CoA oxygenase
EAE94_11880	COG2030	dehydratase
EAE94_11880	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_11885	COG1760	l-serine dehydratase
EAE94_11890	COG0531	amino acid
EAE94_11895	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_11920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAE94_11940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE94_11955	COG0789	Transcriptional regulator
EAE94_11965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAE94_11980	COG2807	transmembrane transport
EAE94_11985	COG0590	tRNA wobble adenosine to inosine editing
EAE94_12090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EAE94_12115	COG1116	anion transmembrane transporter activity
EAE94_12120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE94_12130	COG0864	Transcriptional regulator
EAE94_12145	COG1733	regulation of RNA biosynthetic process
EAE94_12150	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAE94_12155	COG0439	Biotin carboxylase
EAE94_12170	COG1063	alcohol dehydrogenase
EAE94_12180	COG1309	transcriptional regulator
EAE94_12195	COG0038	chloride channel
EAE94_12200	COG4770	biotin carboxylase activity
EAE94_12220	COG1914	H( )-stimulated, divalent metal cation uptake system
EAE94_12225	COG0583	DNA-binding transcription factor activity
EAE94_12260	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAE94_12280	COG2814	Major facilitator Superfamily
EAE94_12300	COG0598	Magnesium transport protein CorA
EAE94_12305	COG1560	Kdo2-lipid A biosynthetic process
EAE94_12320	COG1522	sequence-specific DNA binding
EAE94_12335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EAE94_12345	COG4122	O-methyltransferase activity
EAE94_12375	COG1538	Outer membrane efflux protein
EAE94_12380	COG1137	ATPase activity
EAE94_12385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EAE94_12395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EAE94_12400	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAE94_12400	COG0517	IMP dehydrogenase activity
EAE94_12440	COG2814	Major facilitator Superfamily
EAE94_12480	COG1278	Cold shock
EAE94_12485	COG1280	lysine exporter protein (LysE YggA)
EAE94_12520	COG1570	exodeoxyribonuclease VII activity
EAE94_12575	COG0583	DNA-binding transcription factor activity
EAE94_12580	COG4638	Rieske (2fe-2S)
EAE94_12585	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EAE94_12590	COG0543	2 iron, 2 sulfur cluster binding
EAE94_12590	COG0633	Ferredoxin
EAE94_12595	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_12600	COG3135	benzoate transporter
EAE94_12605	COG2814	Major facilitator Superfamily
EAE94_12620	COG1643	Atp-dependent helicase
EAE94_12625	COG0450	alkyl hydroperoxide reductase
EAE94_12635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EAE94_12645	COG3634	alkyl hydroperoxide reductase activity
EAE94_12665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EAE94_12670	COG0625	glutathione transferase activity
EAE94_12680	COG2885	chlorophyll binding
EAE94_12715	COG0542	response to heat
EAE94_12730	COG1765	OsmC-like protein
EAE94_12740	COG0667	Aldo Keto reductase
EAE94_12755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EAE94_12775	COG0582	viral genome integration into host DNA
EAE94_12915	COG3566	protein conserved in bacteria
EAE94_12940	COG3567	Phage-associated protein, HI1409 family
EAE94_12945	COG5410	chromosome segregation
EAE94_13025	COG4197	protein conserved in bacteria, prophage-related
EAE94_13030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAE94_13080	COG0527	aspartate kinase activity
EAE94_13090	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EAE94_13100	COG3038	cytochrome b561
EAE94_13105	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EAE94_13110	COG2252	PERMEase
EAE94_13120	COG2072	flavoprotein involved in K transport
EAE94_13135	COG1741	Belongs to the pirin family
EAE94_13140	COG1309	transcriptional regulator
EAE94_13150	COG0300	oxidoreductase activity
EAE94_13155	COG2072	flavoprotein involved in K transport
EAE94_13160	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EAE94_13205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE94_13220	COG2814	Major facilitator Superfamily
EAE94_13225	COG1024	Enoyl-CoA hydratase
EAE94_13230	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_13240	COG1960	acyl-CoA dehydrogenase activity
EAE94_13265	COG2186	Transcriptional regulator
EAE94_13270	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_13280	COG4948	Mandelate Racemase Muconate Lactonizing
EAE94_13285	COG2271	Major facilitator Superfamily
EAE94_13290	COG2721	sulfolactate sulfo-lyase activity
EAE94_13295	COG0697	spore germination
EAE94_13325	COG1113	amino acid transport
EAE94_13345	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_13365	COG0531	amino acid
EAE94_13375	COG1113	amino acid transport
EAE94_13420	COG0583	DNA-binding transcription factor activity
EAE94_13430	COG0251	oxidation-reduction process
EAE94_13470	COG1902	pentaerythritol trinitrate reductase activity
EAE94_13470	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAE94_13485	COG2203	Gaf domain
EAE94_13485	COG3706	GGDEF domain
EAE94_13485	COG4251	negative regulation of phosphorylation
EAE94_13485	COG5001	Diguanylate cyclase
EAE94_13495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAE94_13515	COG4172	Belongs to the ABC transporter superfamily
EAE94_13520	COG4239	(ABC) transporter, permease
EAE94_13525	COG4174	ABC transporter (Permease)
EAE94_13535	COG0741	lytic transglycosylase activity
EAE94_13535	COG0741	lytic transglycosylase activity
EAE94_13535	COG1388	LysM domain
EAE94_13535	COG1388	LysM domain
EAE94_13540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAE94_13580	COG0583	DNA-binding transcription factor activity
EAE94_13585	COG1279	arginine transmembrane transporter activity
EAE94_13605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE94_13610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE94_13615	COG0006	proline dipeptidase activity
EAE94_13655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAE94_13680	COG3384	dioxygenase
EAE94_13690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAE94_13695	COG2878	Part of a membrane complex involved in electron transport
EAE94_13700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAE94_13720	COG0768	penicillin binding
EAE94_13725	COG0742	ribosomal rna small subunit methyltransferase
EAE94_13740	COG0830	nickel cation binding
EAE94_13750	COG0804	urea catabolic process
EAE94_13795	COG1253	flavin adenine dinucleotide binding
EAE94_13805	COG2851	Citrate transporter
EAE94_13855	COG1773	rubredoxin
EAE94_13860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAE94_13870	COG0583	DNA-binding transcription factor activity
EAE94_13900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EAE94_13905	COG4181	ATPase activity
EAE94_13950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EAE94_13970	COG0306	phosphate transporter
EAE94_13985	COG3958	Transketolase
EAE94_13990	COG3959	Transketolase, thiamine diphosphate binding domain
EAE94_13995	COG2271	Major facilitator Superfamily
EAE94_14000	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_14005	COG0583	DNA-binding transcription factor activity
EAE94_14030	COG2223	nitrite transmembrane transporter activity
EAE94_14035	COG2207	Transcriptional regulator
EAE94_14040	COG2066	Belongs to the glutaminase family
EAE94_14045	COG0242	peptide deformylase activity
EAE94_14050	COG0477	Major facilitator Superfamily
EAE94_14060	COG0028	Belongs to the TPP enzyme family
EAE94_14075	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_14080	COG2267	carboxylic ester hydrolase activity
EAE94_14090	COG2271	Major facilitator Superfamily
EAE94_14095	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAE94_14105	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_14125	COG1414	Transcriptional regulator
EAE94_14140	COG1024	Enoyl-CoA hydratase
EAE94_14150	COG1215	transferase activity, transferring glycosyl groups
EAE94_14155	COG1649	PFAM Uncharacterised BCR, COG1649
EAE94_14155	COG0726	polysaccharide deacetylase
EAE94_14165	COG4681	YaeQ
EAE94_14175	COG0523	cobalamin synthesis protein
EAE94_14185	COG1607	acyl-coa hydrolase
EAE94_14195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE94_14200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE94_14205	COG1309	transcriptional regulator
EAE94_14230	COG2040	homocysteine
EAE94_14235	COG0531	amino acid
EAE94_14260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE94_14265	COG0477	Major facilitator Superfamily
EAE94_14305	COG0405	Gamma-glutamyltransferase
EAE94_14310	COG2814	Major facilitator Superfamily
EAE94_14320	COG2050	protein possibly involved in aromatic compounds catabolism
EAE94_14335	COG1090	epimerase
EAE94_14355	COG0420	3'-5' exonuclease activity
EAE94_14380	COG0735	belongs to the Fur family
EAE94_14385	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAE94_14410	COG0121	glutamine amidotransferase
EAE94_14425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAE94_14435	COG0210	DNA helicase
EAE94_14440	COG2885	chlorophyll binding
EAE94_14445	COG0204	Acyl-transferase
EAE94_14460	COG2894	cell division
EAE94_14475	COG1280	lysine exporter protein (LysE YggA)
EAE94_14480	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAE94_14480	COG1674	ftsk spoiiie
EAE94_14485	COG0492	ferredoxin-NADP+ reductase activity
EAE94_14490	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EAE94_14500	COG0456	acetyltransferase
EAE94_14545	COG1981	membrane
EAE94_14560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EAE94_14560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAE94_14580	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_14590	COG0657	acetylesterase activity
EAE94_14600	COG0473	3-isopropylmalate dehydrogenase activity
EAE94_14605	COG0583	DNA-binding transcription factor activity
EAE94_14625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE94_14650	COG0564	pseudouridine synthase activity
EAE94_14660	COG0358	DNA primase activity
EAE94_14675	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EAE94_14705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAE94_14735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EAE94_14745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EAE94_14745	COG0351	phosphomethylpyrimidine kinase
EAE94_14745	COG0352	thiamine-phosphate diphosphorylase activity
EAE94_14750	COG1652	LysM domain
EAE94_14775	COG1399	metal-binding, possibly nucleic acid-binding protein
EAE94_14780	COG3101	peptidyl-lysine hydroxylation
EAE94_14785	COG0009	L-threonylcarbamoyladenylate synthase
EAE94_14790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EAE94_14795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EAE94_14810	COG4106	trans-aconitate 2-methyltransferase activity
EAE94_14825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAE94_14825	COG2226	methyltransferase
EAE94_14825	COG0596	Alpha beta hydrolase
EAE94_14830	COG1877	trehalose-phosphatase activity
EAE94_14835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EAE94_14840	COG2223	nitrite transmembrane transporter activity
EAE94_14860	COG1196	nuclear chromosome segregation
EAE94_14870	COG0730	response to heat
EAE94_14885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAE94_14895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAE94_14955	COG0489	protein tyrosine kinase activity
EAE94_14965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAE94_14965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAE94_14995	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EAE94_15000	COG2081	HI0933 family
EAE94_15010	COG0668	transmembrane transport
EAE94_15030	COG0583	DNA-binding transcription factor activity
EAE94_15055	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAE94_15060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAE94_15090	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EAE94_15130	COG0745	RESPONSE REGULATOR receiver
EAE94_15145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAE94_15195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE94_15210	COG0583	DNA-binding transcription factor activity
EAE94_15240	COG0583	DNA-binding transcription factor activity
EAE94_15260	COG0583	DNA-binding transcription factor activity
EAE94_15265	COG1053	succinate dehydrogenase
EAE94_15275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAE94_15280	COG2814	Major facilitator Superfamily
EAE94_15285	COG1960	acyl-CoA dehydrogenase activity
EAE94_15290	COG0583	DNA-binding transcription factor activity
EAE94_15295	COG1063	alcohol dehydrogenase
EAE94_15325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EAE94_15330	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EAE94_15335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAE94_15355	COG2132	Multicopper oxidase
EAE94_15365	COG0561	phosphatase activity
EAE94_15370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAE94_15395	COG1214	PFAM Peptidase M22, glycoprotease
EAE94_15445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EAE94_15455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EAE94_15460	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EAE94_15465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EAE94_15525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAE94_15535	COG1846	Transcriptional regulator
EAE94_15540	COG1764	response to oxidative stress
EAE94_15580	COG0037	tRNA processing
EAE94_15590	COG0248	Ppx GppA phosphatase
EAE94_15620	COG0072	phenylalanine-tRNA ligase activity
EAE94_15660	COG1238	metal cluster binding
EAE94_15665	COG0625	glutathione transferase activity
EAE94_15685	COG0318	PFAM AMP-dependent synthetase and ligase
EAE94_15690	COG3028	Belongs to the UPF0307 family
EAE94_15695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE94_15715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EAE94_15720	COG0617	tRNA 3'-terminal CCA addition
EAE94_15725	COG1555	photosystem II stabilization
EAE94_15730	COG3956	TIGRFAM MazG family protein
EAE94_15740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAE94_15760	COG0784	Response regulator, receiver
EAE94_15760	COG2205	protein histidine kinase activity
EAE94_15760	COG5002	protein histidine kinase activity
EAE94_15765	COG1024	Enoyl-CoA hydratase
EAE94_15770	COG2084	Dehydrogenase
EAE94_15775	COG3622	Belongs to the hyi family
EAE94_15805	COG0697	spore germination
EAE94_15815	COG2814	Major facilitator Superfamily
EAE94_15820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAE94_15830	COG0583	DNA-binding transcription factor activity
EAE94_15840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EAE94_15850	COG0084	hydrolase, TatD family'
EAE94_15865	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EAE94_15920	COG0440	acetolactate synthase activity
EAE94_15925	COG0028	Belongs to the TPP enzyme family
EAE94_15950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE94_15955	COG0577	efflux transmembrane transporter activity
EAE94_15955	COG1136	(ABC) transporter
EAE94_15960	COG1538	Outer membrane efflux protein
EAE94_15975	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EAE94_15980	COG1162	GTPase activity
EAE94_15990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAE94_16010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAE94_16015	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_16055	COG2986	histidine ammonia-lyase
EAE94_16065	COG1216	Glycosyl transferase, family 2
EAE94_16070	COG0318	PFAM AMP-dependent synthetase and ligase
EAE94_16080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAE94_16125	COG1426	Protein conserved in bacteria
EAE94_16160	COG0793	Belongs to the peptidase S41A family
EAE94_16175	COG2267	carboxylic ester hydrolase activity
EAE94_16185	COG1012	belongs to the aldehyde dehydrogenase family
EAE94_16190	COG3265	gluconokinase activity
EAE94_16200	COG0800	Aldolase
EAE94_16210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAE94_16215	COG0280	phosphate acetyltransferase
EAE94_16215	COG0857	belongs to the CobB CobQ family
EAE94_16220	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAE94_16220	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAE94_16240	COG0740	serine-type endopeptidase activity
EAE94_16250	COG4774	siderophore transport
EAE94_16260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAE94_16270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAE94_16270	COG2813	Specifically methylates the guanine in position
EAE94_16370	COG0788	formyltetrahydrofolate deformylase activity
EAE94_16395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAE94_16395	COG4651	solute:proton antiporter activity
EAE94_16415	COG0724	RNA recognition motif
EAE94_16420	COG0210	DNA helicase
EAE94_16445	COG1733	regulation of RNA biosynthetic process
EAE94_16455	COG2900	Belongs to the SlyX family
EAE94_16460	COG0488	(ABC) transporter
EAE94_16465	COG1280	lysine exporter protein (LysE YggA)
EAE94_16470	COG1560	Kdo2-lipid A biosynthetic process
EAE94_16480	COG1301	dicarboxylic acid transport
EAE94_16535	COG0473	3-isopropylmalate dehydrogenase activity
EAE94_16590	COG0583	DNA-binding transcription factor activity
EAE94_16600	COG0625	glutathione transferase activity
EAE94_16605	COG2378	regulation of single-species biofilm formation
EAE94_16610	COG0546	phosphoglycolate phosphatase activity
EAE94_16625	COG1530	ribonuclease E activity
EAE94_16630	COG0318	PFAM AMP-dependent synthetase and ligase
EAE94_16645	COG0583	DNA-binding transcription factor activity
EAE94_16650	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_16655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAE94_16665	COG0534	Mate efflux family protein
EAE94_16680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EAE94_16705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE94_16705	COG0493	'glutamate synthase
EAE94_16715	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EAE94_16720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAE94_16735	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EAE94_16745	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EAE94_16745	COG0644	oxidoreductase
EAE94_16755	COG0425	Belongs to the sulfur carrier protein TusA family
EAE94_16760	COG4535	Mg2 and Co2 transporter CorC
EAE94_16770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAE94_16790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EAE94_16795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAE94_16795	COG0475	glutathione-regulated potassium exporter activity
EAE94_16810	COG0484	heat shock protein binding
EAE94_16815	COG0789	Transcriptional regulator
EAE94_16820	COG0598	Magnesium transport protein CorA
EAE94_16835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAE94_16840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAE94_16845	COG1074	ATP-dependent DNA helicase activity
EAE94_16850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EAE94_16870	COG2226	methyltransferase
EAE94_16890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EAE94_16905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAE94_16905	COG2111	Na H antiporter
EAE94_16910	COG1006	Multisubunit Na H antiporter MnhC subunit
EAE94_16915	COG0651	ATP synthesis coupled electron transport
EAE94_16920	COG1863	multisubunit Na H antiporter MnhE subunit
EAE94_16925	COG2212	antiporter activity
EAE94_16930	COG1320	monovalent cation:proton antiporter activity
EAE94_16945	COG0195	Participates in both transcription termination and antitermination
EAE94_16995	COG0237	dephospho-CoA kinase activity
EAE94_17005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAE94_17020	COG0497	DNA recombination
EAE94_17030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EAE94_17060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAE94_17060	COG2169	Transcriptional regulator
EAE94_17065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EAE94_17135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EAE94_17150	COG0326	Molecular chaperone. Has ATPase activity
EAE94_17165	COG2056	Na+-H+ antiporter family
EAE94_17170	COG0596	Alpha beta hydrolase
EAE94_17265	COG0546	phosphoglycolate phosphatase activity
EAE94_17270	COG1716	ATPase activity
EAE94_17315	COG0181	hydroxymethylbilane synthase activity
EAE94_17325	COG3275	phosphorelay sensor kinase activity
EAE94_17345	COG1538	Outer membrane efflux protein
EAE94_17350	COG0697	spore germination
EAE94_17375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EAE94_17380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAE94_17385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAE94_17390	COG0772	Belongs to the SEDS family
EAE94_17415	COG4974	Belongs to the 'phage' integrase family
EAE94_17420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAE94_17430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EAE94_17440	COG2197	response regulator
EAE94_17455	COG0793	Belongs to the peptidase S41A family
EAE94_17460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EAE94_17465	COG0795	lipopolysaccharide-transporting ATPase activity
EAE94_17505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAE94_17505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAE94_17515	COG0004	ammonium transporteR
EAE94_17520	COG0347	Belongs to the P(II) protein family
EAE94_17530	COG0606	chelatase, subunit chli
EAE94_17540	COG0659	secondary active sulfate transmembrane transporter activity
EAE94_17545	COG0589	response to stress
EAE94_17595	COG0606	chelatase, subunit chli
EAE94_17600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE94_17610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE94_17625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EAE94_17640	COG0318	PFAM AMP-dependent synthetase and ligase
EAE94_17650	COG0477	Major facilitator Superfamily
EAE94_17655	COG2860	membrane
EAE94_17660	COG3012	SEC-C Motif Domain Protein
EAE94_17665	COG1253	flavin adenine dinucleotide binding
EAE94_17675	COG0477	Major facilitator Superfamily
EAE94_17685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAE94_17720	COG0655	NAD(P)H dehydrogenase (quinone) activity
EAE94_17730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EAE94_17765	COG1309	transcriptional regulator
EAE94_17800	COG0758	DNA mediated transformation
EAE94_17810	COG0697	spore germination
EAE94_17815	COG1309	transcriptional regulator
EAE94_17830	COG0386	Belongs to the glutathione peroxidase family
EAE94_17900	COG1121	(ABC) transporter
EAE94_17905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAE94_17910	COG1280	lysine exporter protein (LysE YggA)
EAE94_17915	COG2837	iron assimilation
EAE94_17920	COG0281	malic enzyme
EAE94_17965	COG0519	Catalyzes the synthesis of GMP from XMP
EAE94_17965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAE94_17970	COG4399	Belongs to the UPF0754 family
EAE94_17975	COG2259	Doxx family
EAE94_17980	COG0586	Pfam SNARE associated Golgi protein
EAE94_17995	COG1192	Involved in chromosome partitioning
EAE94_18005	COG0271	Belongs to the BolA IbaG family
EAE94_18045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAE94_18045	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EAE94_18045	COG3321	synthase
EAE94_18045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAE94_18050	COG1960	acyl-CoA dehydrogenase activity
EAE94_18055	COG0318	PFAM AMP-dependent synthetase and ligase
EAE94_18060	COG2197	response regulator
EAE94_18070	COG3916	Acyl-homoserine-lactone synthase
EAE94_18075	COG0477	Major facilitator Superfamily
EAE94_18080	COG1024	Enoyl-CoA hydratase
EAE94_18085	COG1024	Enoyl-CoA hydratase
EAE94_18090	COG1960	acyl-CoA dehydrogenase activity
EAE94_18095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAE94_18115	COG1113	amino acid transport
EAE94_18120	COG1113	amino acid transport
EAE94_18125	COG0251	oxidation-reduction process
EAE94_18165	COG0564	pseudouridine synthase activity
EAE94_18245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAE94_18260	COG1802	Transcriptional regulator
EAE94_18270	COG1448	Aminotransferase
EAE94_18275	COG0277	FAD linked oxidase domain protein
EAE94_18285	COG2186	Transcriptional regulator
EAE94_18295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAE94_18300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAE94_18315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EAE94_18320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EAE94_18345	COG0438	transferase activity, transferring glycosyl groups
EAE94_18375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EAE94_18405	COG0728	peptidoglycan biosynthetic process
EAE94_18410	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAE94_18465	COG0546	phosphoglycolate phosphatase activity
EAE94_18470	COG1028	Short-chain dehydrogenase reductase Sdr
EAE94_18490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAE94_18495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAE94_18500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE94_18505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAE94_18510	COG1116	anion transmembrane transporter activity
EAE94_18515	COG1309	transcriptional regulator
EAE94_18520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAE94_18530	COG0196	riboflavin kinase activity
EAE94_18535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EAE94_18545	COG1047	Peptidyl-prolyl cis-trans
EAE94_18585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAE94_18590	COG0657	acetylesterase activity
EAE94_18640	COG2951	lytic endotransglycosylase activity
EAE94_18645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAE94_18665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAE94_18675	COG0671	phosphoesterase, PA-phosphatase related
EAE94_18680	COG0861	Integral membrane protein TerC family
EAE94_18690	COG0754	glutathionylspermidine amidase activity
EAE94_18700	COG0402	S-adenosylhomocysteine deaminase activity
EAE94_18715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAE94_18720	COG1230	cation diffusion facilitator family transporter
EAE94_18735	COG0706	membrane insertase activity
EAE94_18765	COG4691	Plasmid stability protein
EAE94_18800	COG0798	PFAM Bile acid sodium symporter
EAE94_18840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAE94_18890	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EAE94_18920	COG0659	secondary active sulfate transmembrane transporter activity
EAE94_18925	COG0589	response to stress
EAE94_18985	COG0501	Belongs to the peptidase M48B family
EAE94_19175	COG0739	heme binding
EAE94_19205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAE94_19220	COG1192	Involved in chromosome partitioning
EAE94_19270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAE94_19405	COG1525	nuclease
EAE94_19485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAE94_19515	COG0640	Transcriptional regulator