locus-tag	class	description
EAV54_00010	COG0592	DNA-directed DNA polymerase activity
EAV54_00020	COG0187	DNA topoisomerase II activity
EAV54_00030	COG0586	Pfam SNARE associated Golgi protein
EAV54_00035	COG0488	(ABC) transporter
EAV54_00060	COG0596	Alpha beta hydrolase
EAV54_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EAV54_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EAV54_00115	COG0733	neurotransmitter:sodium symporter activity
EAV54_00155	COG2233	PERMEase
EAV54_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAV54_00205	COG2814	Major facilitator Superfamily
EAV54_00210	COG0656	L-ascorbic acid biosynthetic process
EAV54_00215	COG0583	DNA-binding transcription factor activity
EAV54_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAV54_00235	COG1064	alcohol dehydrogenase
EAV54_00240	COG2818	Glycosylase
EAV54_00255	COG1194	a g-specific adenine glycosylase
EAV54_00275	COG2983	Belongs to the UPF0260 family
EAV54_00280	COG2133	pyrroloquinoline quinone binding
EAV54_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EAV54_00290	COG2116	formate transmembrane transporter activity
EAV54_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAV54_00315	COG1335	isochorismatase
EAV54_00320	COG0385	Bile acid
EAV54_00325	COG0534	Mate efflux family protein
EAV54_00330	COG1683	Conserved Protein
EAV54_00350	COG0625	glutathione transferase activity
EAV54_00360	COG1113	amino acid transport
EAV54_00370	COG0523	cobalamin synthesis protein
EAV54_00380	COG2188	Transcriptional regulator
EAV54_00410	COG0010	Belongs to the arginase family
EAV54_00430	COG1280	lysine exporter protein (LysE YggA)
EAV54_00450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EAV54_00460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EAV54_00465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EAV54_00515	COG0753	catalase activity
EAV54_00565	COG0534	Mate efflux family protein
EAV54_00570	COG0436	Aminotransferase
EAV54_00575	COG2733	membrane
EAV54_00590	COG2918	glutathione biosynthetic process
EAV54_00605	COG1388	LysM domain
EAV54_00605	COG1705	Flagellar rod assembly protein muramidase FlgJ
EAV54_00640	COG3150	esterase
EAV54_00650	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EAV54_00660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAV54_00670	COG2233	PERMEase
EAV54_00675	COG2351	hydroxyisourate hydrolase activity
EAV54_00710	COG3706	GGDEF domain
EAV54_00725	COG1393	Belongs to the ArsC family
EAV54_00730	COG0708	Exodeoxyribonuclease III
EAV54_00755	COG0189	ligase activity
EAV54_00775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EAV54_00785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAV54_00800	COG4942	peptidase
EAV54_00810	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAV54_00820	COG2119	membrane
EAV54_00825	COG4774	siderophore transport
EAV54_00830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAV54_00830	COG0426	domain, Protein
EAV54_00855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EAV54_00875	COG1902	pentaerythritol trinitrate reductase activity
EAV54_00880	COG1519	Transferase
EAV54_00890	COG0668	transmembrane transport
EAV54_00900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAV54_00905	COG1335	isochorismatase
EAV54_00910	COG1522	sequence-specific DNA binding
EAV54_00935	COG0784	Response regulator, receiver
EAV54_00935	COG2198	Histidine kinase
EAV54_00935	COG2205	protein histidine kinase activity
EAV54_00940	COG3162	membrane
EAV54_00945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAV54_00955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAV54_00970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EAV54_00975	COG1309	transcriptional regulator
EAV54_00995	COG0351	phosphomethylpyrimidine kinase
EAV54_00995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EAV54_00995	COG0352	thiamine-phosphate diphosphorylase activity
EAV54_01005	COG2814	Major facilitator Superfamily
EAV54_01020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EAV54_01030	COG1113	amino acid transport
EAV54_01040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAV54_01045	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_01055	COG1335	isochorismatase
EAV54_01095	COG2814	Major facilitator Superfamily
EAV54_01100	COG0583	DNA-binding transcription factor activity
EAV54_01145	COG1733	regulation of RNA biosynthetic process
EAV54_01175	COG1733	regulation of RNA biosynthetic process
EAV54_01185	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAV54_01205	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EAV54_01210	COG2207	Transcriptional regulator
EAV54_01265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAV54_01280	COG2329	Antibiotic biosynthesis monooxygenase
EAV54_01310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EAV54_01340	COG0427	acetyl-CoA hydrolase
EAV54_01365	COG0659	secondary active sulfate transmembrane transporter activity
EAV54_01370	COG4221	oxidoreductase activity
EAV54_01395	COG0488	(ABC) transporter
EAV54_01460	COG0833	amino acid
EAV54_01505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAV54_01510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EAV54_01525	COG2226	methyltransferase
EAV54_01575	COG0069	glutamate synthase activity
EAV54_01575	COG0070	glutamate synthase
EAV54_01575	COG0067	glutamate synthase
EAV54_01580	COG0493	'glutamate synthase
EAV54_01590	COG1704	LemA family
EAV54_01595	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EAV54_01605	COG4969	Belongs to the N-Me-Phe pilin family
EAV54_01610	COG3307	-O-antigen
EAV54_01630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAV54_01645	COG0194	GDP metabolic process
EAV54_01695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EAV54_01715	COG5380	lipid catabolic process
EAV54_01720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EAV54_01745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAV54_01750	COG0277	FAD linked oxidase domain protein
EAV54_01760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EAV54_01765	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAV54_01780	COG1289	transmembrane transporter activity
EAV54_01790	COG0628	permease
EAV54_01795	COG1192	Involved in chromosome partitioning
EAV54_01825	COG0833	amino acid
EAV54_01830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAV54_01835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAV54_01845	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_01885	COG0583	DNA-binding transcription factor activity
EAV54_01935	COG0517	IMP dehydrogenase activity
EAV54_01940	COG1983	PspC domain protein
EAV54_01950	COG1960	acyl-CoA dehydrogenase activity
EAV54_01965	COG0408	coproporphyrinogen oxidase activity
EAV54_01985	COG0513	Belongs to the DEAD box helicase family
EAV54_01990	COG1127	ABC transporter
EAV54_01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAV54_02005	COG2854	intermembrane phospholipid transfer
EAV54_02015	COG0598	Magnesium transport protein CorA
EAV54_02025	COG0494	nUDIX hydrolase
EAV54_02030	COG1040	competence protein
EAV54_02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EAV54_02055	COG1946	Acyl-CoA thioesterase
EAV54_02060	COG1301	dicarboxylic acid transport
EAV54_02075	COG1959	2 iron, 2 sulfur cluster binding
EAV54_02080	COG1017	nitric oxide dioxygenase activity
EAV54_02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAV54_02090	COG0433	COG0433 Predicted ATPase
EAV54_02095	COG0626	cystathionine gamma-synthase activity
EAV54_02250	COG1960	acyl-CoA dehydrogenase activity
EAV54_02255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EAV54_02285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EAV54_02290	COG0339	signal peptide processing
EAV54_02295	COG0557	exoribonuclease II activity
EAV54_02340	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAV54_02345	COG2169	Transcriptional regulator
EAV54_02350	COG0697	spore germination
EAV54_02355	COG1295	ribonuclease BN
EAV54_02390	COG1702	phosphate starvation-inducible protein PhoH
EAV54_02400	COG0739	heme binding
EAV54_02400	COG0741	lytic transglycosylase activity
EAV54_02400	COG1196	nuclear chromosome segregation
EAV54_02430	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EAV54_02435	COG1183	phosphatidylcholine synthase activity
EAV54_02480	COG1960	acyl-CoA dehydrogenase activity
EAV54_02485	COG1309	transcriptional regulator
EAV54_02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EAV54_02505	COG1960	acyl-CoA dehydrogenase activity
EAV54_02525	COG2969	positive regulation of protein catabolic process
EAV54_02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EAV54_02545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EAV54_02550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EAV54_02555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAV54_02575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAV54_02585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAV54_02600	COG2199	diguanylate cyclase activity
EAV54_02660	COG1607	acyl-coa hydrolase
EAV54_02695	COG3013	Belongs to the UPF0304 family
EAV54_02775	COG2205	protein histidine kinase activity
EAV54_02790	COG2132	Multicopper oxidase
EAV54_02815	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAV54_02865	COG0582	viral genome integration into host DNA
EAV54_02890	COG2350	Protein conserved in bacteria
EAV54_02900	COG0613	PHP domain protein
EAV54_02905	COG3781	membrane
EAV54_02915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAV54_02920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAV54_02930	COG1862	Preprotein translocase
EAV54_02960	COG0582	viral genome integration into host DNA
EAV54_02985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAV54_03005	COG2205	protein histidine kinase activity
EAV54_03010	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EAV54_03030	COG0726	polysaccharide deacetylase
EAV54_03035	COG0463	Glycosyl transferase, family 2
EAV54_03040	COG0438	transferase activity, transferring glycosyl groups
EAV54_03055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EAV54_03105	COG1960	acyl-CoA dehydrogenase activity
EAV54_03110	COG1960	acyl-CoA dehydrogenase activity
EAV54_03120	COG2205	protein histidine kinase activity
EAV54_03125	COG0745	RESPONSE REGULATOR receiver
EAV54_03130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EAV54_03150	COG2096	Adenosyltransferase
EAV54_03155	COG4206	TonB-dependent receptor
EAV54_03200	COG0285	dihydrofolate synthase activity
EAV54_03220	COG0450	alkyl hydroperoxide reductase
EAV54_03235	COG0477	Major facilitator Superfamily
EAV54_03240	COG1272	protein, Hemolysin III
EAV54_03250	COG2153	protein acetylation
EAV54_03270	COG0183	Belongs to the thiolase family
EAV54_03275	COG2207	Transcriptional regulator
EAV54_03295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAV54_03315	COG0183	Belongs to the thiolase family
EAV54_03335	COG1690	Belongs to the RtcB family
EAV54_03340	COG0833	amino acid
EAV54_03350	COG2233	PERMEase
EAV54_03355	COG1217	gtp-binding protein TYPA
EAV54_03380	COG2094	Belongs to the DNA glycosylase MPG family
EAV54_03385	COG4772	TonB-dependent receptor
EAV54_03390	COG1902	pentaerythritol trinitrate reductase activity
EAV54_03405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAV54_03410	COG0354	folic acid binding
EAV54_03420	COG3189	MarR family transcriptional regulator
EAV54_03425	COG2824	Alkylphosphonate utilization operon protein PhnA
EAV54_03430	COG3422	double-strand break repair
EAV54_03470	COG0840	transmembrane signaling receptor activity
EAV54_03490	COG5510	response to toxic substance
EAV54_03500	COG2832	Protein of unknown function (DUF454)
EAV54_03505	COG1376	ErfK ybiS ycfS ynhG family protein
EAV54_03545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EAV54_03555	COG1289	transmembrane transporter activity
EAV54_03560	COG2814	Major facilitator Superfamily
EAV54_03580	COG1115	amino acid carrier protein
EAV54_03585	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAV54_03590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAV54_03595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EAV54_03600	COG3590	peptidase
EAV54_03625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAV54_03635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAV54_03640	COG1077	Cell shape determining protein MreB Mrl
EAV54_03645	COG1792	Involved in formation and maintenance of cell shape
EAV54_03650	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EAV54_03655	COG0424	maF-like protein
EAV54_03660	COG1530	ribonuclease E activity
EAV54_03670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAV54_03680	COG0560	Phosphoserine phosphatase
EAV54_03690	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAV54_03715	COG2207	Transcriptional regulator
EAV54_03735	COG1113	amino acid transport
EAV54_03740	COG2828	Protein conserved in bacteria
EAV54_03745	COG0142	geranyltranstransferase activity
EAV54_03750	COG2315	Protein conserved in bacteria
EAV54_03765	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAV54_03785	COG2194	sulfuric ester hydrolase activity
EAV54_03790	COG0745	RESPONSE REGULATOR receiver
EAV54_03795	COG0642	Histidine kinase
EAV54_03805	COG0004	ammonium transporteR
EAV54_03815	COG0583	DNA-binding transcription factor activity
EAV54_03835	COG0525	valine-tRNA ligase activity
EAV54_03845	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_03855	COG0393	Putative heavy-metal-binding
EAV54_03860	COG0393	Putative heavy-metal-binding
EAV54_03865	COG1538	Outer membrane efflux protein
EAV54_03875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAV54_03880	COG0671	phosphoesterase, PA-phosphatase related
EAV54_03910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EAV54_03925	COG1648	precorrin-2 dehydrogenase activity
EAV54_03925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EAV54_03930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EAV54_03935	COG1733	regulation of RNA biosynthetic process
EAV54_03945	COG0531	amino acid
EAV54_03960	COG0321	lipoyl(octanoyl) transferase activity
EAV54_03965	COG2921	Belongs to the UPF0250 family
EAV54_04005	COG2009	succinate dehydrogenase
EAV54_04010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EAV54_04015	COG1053	succinate dehydrogenase
EAV54_04020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAV54_04045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAV54_04065	COG2354	Protein conserved in bacteria
EAV54_04070	COG2321	neutral zinc metallopeptidase
EAV54_04095	COG2843	Capsule synthesis protein
EAV54_04110	COG0589	response to stress
EAV54_04120	COG0251	oxidation-reduction process
EAV54_04125	COG1309	transcriptional regulator
EAV54_04140	COG0505	Belongs to the CarA family
EAV54_04165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAV54_04170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EAV54_04220	COG0477	Major facilitator Superfamily
EAV54_04225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EAV54_04240	COG1597	lipid kinase activity
EAV54_04245	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EAV54_04265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAV54_04270	COG0584	glycerophosphoryl diester phosphodiesterase
EAV54_04290	COG0741	lytic transglycosylase activity
EAV54_04315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAV54_04330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAV54_04340	COG3811	Belongs to the UPF0386 family
EAV54_04400	COG0778	Nitroreductase
EAV54_04415	COG1929	Belongs to the glycerate kinase type-1 family
EAV54_04420	COG0243	molybdopterin cofactor binding
EAV54_04425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EAV54_04430	COG3339	Conserved Protein
EAV54_04440	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EAV54_04455	COG1113	amino acid transport
EAV54_04465	COG0019	diaminopimelate decarboxylase activity
EAV54_04475	COG1280	lysine exporter protein (LysE YggA)
EAV54_04480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EAV54_04510	COG0463	Glycosyl transferase, family 2
EAV54_04530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAV54_04560	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAV54_04565	COG1136	(ABC) transporter
EAV54_04570	COG0658	competence protein
EAV54_04570	COG2333	competence protein COMEC
EAV54_04580	COG0616	signal peptide processing
EAV54_04580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EAV54_04585	COG0596	Alpha beta hydrolase
EAV54_04590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAV54_04600	COG0628	permease
EAV54_04635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAV54_04655	COG0823	Involved in the tonB-independent uptake of proteins
EAV54_04675	COG0824	Thioesterase
EAV54_04680	COG1473	amidohydrolase
EAV54_04700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAV54_04700	COG0047	phosphoribosylformylglycinamidine synthase activity
EAV54_04730	COG1169	isochorismate synthase
EAV54_04735	COG1535	isochorismatase
EAV54_04735	COG3433	isochorismatase activity
EAV54_04740	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_04745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAV54_04750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAV54_04750	COG2226	methyltransferase
EAV54_04750	COG3433	isochorismatase activity
EAV54_04755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAV54_04760	COG1021	2,3-dihydroxybenzoate-AMP ligase
EAV54_04765	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EAV54_04770	COG0019	diaminopimelate decarboxylase activity
EAV54_04790	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EAV54_04795	COG4774	siderophore transport
EAV54_04810	COG0534	Mate efflux family protein
EAV54_04820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAV54_04895	COG1024	Enoyl-CoA hydratase
EAV54_04900	COG1056	cytidyltransferase-related domain
EAV54_04900	COG1051	belongs to the nudix hydrolase family
EAV54_04910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAV54_04925	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EAV54_04940	COG4625	pathogenesis
EAV54_04945	COG0583	DNA-binding transcription factor activity
EAV54_04950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAV54_04955	COG4208	sulfate ABC transporter
EAV54_04960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EAV54_04970	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAV54_04975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAV54_04980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAV54_05000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAV54_05010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAV54_05020	COG0681	Belongs to the peptidase S26 family
EAV54_05035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EAV54_05045	COG1381	Involved in DNA repair and RecF pathway recombination
EAV54_05050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EAV54_05060	COG4221	oxidoreductase activity
EAV54_05090	COG0443	Heat shock 70 kDa protein
EAV54_05100	COG0436	Aminotransferase
EAV54_05120	COG0556	nucleotide-excision repair
EAV54_05175	COG2070	2-Nitropropane dioxygenase
EAV54_05205	COG1215	transferase activity, transferring glycosyl groups
EAV54_05220	COG0415	Belongs to the DNA photolyase family
EAV54_05230	COG1252	NADH dehydrogenase
EAV54_05235	COG1686	Belongs to the peptidase S11 family
EAV54_05250	COG1187	pseudouridine synthase activity
EAV54_05275	COG0477	Major facilitator Superfamily
EAV54_05280	COG0583	DNA-binding transcription factor activity
EAV54_05285	COG1823	symporter activity
EAV54_05295	COG0612	Peptidase, M16
EAV54_05320	COG0352	thiamine-phosphate diphosphorylase activity
EAV54_05355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAV54_05365	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAV54_05380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAV54_05385	COG0076	glutamate decarboxylase activity
EAV54_05395	COG1522	sequence-specific DNA binding
EAV54_05400	COG3961	Belongs to the TPP enzyme family
EAV54_05405	COG1113	amino acid transport
EAV54_05410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAV54_05415	COG0573	inorganic phosphate transmembrane transporter activity
EAV54_05425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EAV54_05430	COG0616	signal peptide processing
EAV54_05465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAV54_05470	COG1686	Belongs to the peptidase S11 family
EAV54_05495	COG0583	DNA-binding transcription factor activity
EAV54_05500	COG1067	ATP-dependent peptidase activity
EAV54_05525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EAV54_05545	COG1966	Carbon starvation protein
EAV54_05550	COG2879	small protein
EAV54_05590	COG1335	isochorismatase
EAV54_05595	COG0583	DNA-binding transcription factor activity
EAV54_05610	COG0596	Alpha beta hydrolase
EAV54_05620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAV54_05660	COG1741	Belongs to the pirin family
EAV54_05670	COG2964	Protein conserved in bacteria
EAV54_05685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAV54_05690	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAV54_05695	COG4605	iron ion homeostasis
EAV54_05700	COG4604	ABC transporter, ATP-binding protein
EAV54_05705	COG4607	ABC-type enterochelin transport system periplasmic component
EAV54_05710	COG4774	siderophore transport
EAV54_05720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAV54_05725	COG1021	2,3-dihydroxybenzoate-AMP ligase
EAV54_05730	COG3433	isochorismatase activity
EAV54_05730	COG1535	isochorismatase
EAV54_05745	COG1132	(ABC) transporter
EAV54_05750	COG1132	(ABC) transporter
EAV54_05755	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EAV54_05780	COG3739	integral membrane protein
EAV54_05800	COG0302	gtp cyclohydrolase
EAV54_05810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EAV54_05840	COG0308	aminopeptidase N
EAV54_05845	COG0512	Glutamine amidotransferase of anthranilate synthase
EAV54_05860	COG0174	glutamine synthetase
EAV54_05870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EAV54_05905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EAV54_05910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAV54_05915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAV54_05935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EAV54_05940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EAV54_05945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EAV54_05960	COG1960	acyl-CoA dehydrogenase activity
EAV54_05965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EAV54_05970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAV54_05980	COG2223	nitrite transmembrane transporter activity
EAV54_05990	COG0024	Methionine aminopeptidase
EAV54_05995	COG0052	Belongs to the universal ribosomal protein uS2 family
EAV54_06010	COG2207	Transcriptional regulator
EAV54_06035	COG2951	lytic endotransglycosylase activity
EAV54_06040	COG0772	Belongs to the SEDS family
EAV54_06055	COG0842	Transport permease protein
EAV54_06060	COG1131	(ABC) transporter
EAV54_06105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAV54_06120	COG4215	(ABC) transporter
EAV54_06125	COG4160	amino acid transport
EAV54_06130	COG4598	ABC transporter
EAV54_06140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAV54_06145	COG0826	peptidase U32
EAV54_06150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAV54_06165	COG1720	tRNA m6t6A37 methyltransferase activity
EAV54_06175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAV54_06190	COG0642	Histidine kinase
EAV54_06200	COG0494	nUDIX hydrolase
EAV54_06210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAV54_06215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EAV54_06220	COG3139	Protein of unknown function (DUF1315)
EAV54_06225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAV54_06235	COG1301	dicarboxylic acid transport
EAV54_06240	COG1960	acyl-CoA dehydrogenase activity
EAV54_06245	COG2819	hydrolase of the alpha beta superfamily
EAV54_06255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EAV54_06265	COG2195	Cleaves the N-terminal amino acid of tripeptides
EAV54_06285	COG1690	Belongs to the RtcB family
EAV54_06290	COG1234	tRNA 3'-trailer cleavage
EAV54_06295	COG4650	regulator
EAV54_06325	COG2363	Small membrane protein
EAV54_06345	COG0513	Belongs to the DEAD box helicase family
EAV54_06355	COG0778	Nitroreductase
EAV54_06385	COG1286	toxin biosynthetic process
EAV54_06410	COG4783	chaperone-mediated protein folding
EAV54_06415	COG1610	YqeY-like protein
EAV54_06445	COG0515	serine threonine protein kinase
EAV54_06445	COG2815	serine threonine protein kinase
EAV54_06515	COG3111	PFAM Bacterial OB fold (BOF) protein
EAV54_06540	COG3243	poly(R)-hydroxyalkanoic acid synthase
EAV54_06545	COG0786	glutamate:sodium symporter activity
EAV54_06555	COG2186	Transcriptional regulator
EAV54_06605	COG0477	Major facilitator Superfamily
EAV54_06610	COG1051	belongs to the nudix hydrolase family
EAV54_06640	COG2995	paraquat-inducible protein a
EAV54_06645	COG3008	intermembrane lipid transfer
EAV54_06645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAV54_06660	COG1794	racemase activity, acting on amino acids and derivatives
EAV54_06690	COG1301	dicarboxylic acid transport
EAV54_06700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAV54_06705	COG2011	ABC-type metal ion transport system permease component
EAV54_06710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAV54_06715	COG1464	Belongs to the NlpA lipoprotein family
EAV54_06720	COG0151	Belongs to the GarS family
EAV54_06725	COG0138	bifunctional purine biosynthesis protein purh
EAV54_06730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EAV54_06760	COG2308	Evidence 4 Homologs of previously reported genes of
EAV54_06770	COG1305	Transglutaminase-like
EAV54_06780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAV54_06785	COG0305	Participates in initiation and elongation during chromosome replication
EAV54_06810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EAV54_06820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EAV54_06825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EAV54_06850	COG0726	polysaccharide deacetylase
EAV54_06850	COG1649	PFAM Uncharacterised BCR, COG1649
EAV54_06855	COG1215	transferase activity, transferring glycosyl groups
EAV54_06860	COG3658	cytochrome
EAV54_06870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAV54_06890	COG0583	DNA-binding transcription factor activity
EAV54_06920	COG1960	acyl-CoA dehydrogenase activity
EAV54_06925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAV54_06930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAV54_06945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAV54_06955	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EAV54_06960	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EAV54_06965	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EAV54_06970	COG2205	protein histidine kinase activity
EAV54_06975	COG0745	RESPONSE REGULATOR receiver
EAV54_06980	COG0174	glutamine synthetase
EAV54_07000	COG0729	surface antigen
EAV54_07030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAV54_07035	COG2814	Major facilitator Superfamily
EAV54_07050	COG0583	DNA-binding transcription factor activity
EAV54_07065	COG1187	pseudouridine synthase activity
EAV54_07085	COG0802	atpase or kinase
EAV54_07090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EAV54_07100	COG1923	regulation of RNA biosynthetic process
EAV54_07105	COG0697	spore germination
EAV54_07130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAV54_07135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAV54_07135	COG0519	Catalyzes the synthesis of GMP from XMP
EAV54_07140	COG4302	ethanolamine ammonia-lyase activity
EAV54_07145	COG4303	Ethanolamine ammonia lyase large subunit
EAV54_07150	COG0531	amino acid
EAV54_07170	COG1454	alcohol dehydrogenase
EAV54_07175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAV54_07200	COG0308	aminopeptidase N
EAV54_07240	COG1605	Chorismate mutase
EAV54_07255	COG1309	transcriptional regulator
EAV54_07265	COG0668	transmembrane transport
EAV54_07295	COG4773	Receptor
EAV54_07315	COG0488	(ABC) transporter
EAV54_07320	COG0589	response to stress
EAV54_07335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EAV54_07345	COG3135	benzoate transporter
EAV54_07350	COG1522	sequence-specific DNA binding
EAV54_07360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAV54_07365	COG0583	DNA-binding transcription factor activity
EAV54_07375	COG0183	Belongs to the thiolase family
EAV54_07385	COG2030	dehydratase
EAV54_07390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAV54_07405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAV54_07415	COG0824	Thioesterase
EAV54_07420	COG1454	alcohol dehydrogenase
EAV54_07430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EAV54_07450	COG0069	glutamate synthase activity
EAV54_07595	COG3617	BRO family, N-terminal domain
EAV54_07630	COG5410	chromosome segregation
EAV54_07740	COG1598	PFAM Uncharacterised protein family UPF0150
EAV54_07805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAV54_07820	COG2814	Major facilitator Superfamily
EAV54_07835	COG0511	ligase activity, forming carbon-carbon bonds
EAV54_07855	COG1116	anion transmembrane transporter activity
EAV54_07855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAV54_07860	COG0745	RESPONSE REGULATOR receiver
EAV54_07870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAV54_07870	COG2146	nitrite reductase [NAD(P)H] activity
EAV54_07875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAV54_07880	COG0243	molybdopterin cofactor binding
EAV54_07890	COG0243	molybdopterin cofactor binding
EAV54_07895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EAV54_07910	COG0315	cyclic pyranopterin monophosphate synthase activity
EAV54_07910	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAV54_07915	COG0303	'Molybdopterin
EAV54_07925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAV54_07930	COG0697	spore germination
EAV54_07950	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EAV54_07955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAV54_08015	COG2204	response regulator
EAV54_08020	COG3852	Histidine kinase
EAV54_08045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EAV54_08050	COG0575	Belongs to the CDS family
EAV54_08065	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAV54_08085	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAV54_08100	COG2137	regulation of response to DNA damage stimulus
EAV54_08110	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EAV54_08115	COG1011	Hydrolase
EAV54_08140	COG1522	sequence-specific DNA binding
EAV54_08150	COG1113	amino acid transport
EAV54_08165	COG0659	secondary active sulfate transmembrane transporter activity
EAV54_08170	COG2135	peptidase activity
EAV54_08185	COG3300	MHYT domain
EAV54_08185	COG5001	Diguanylate cyclase
EAV54_08200	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EAV54_08200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAV54_08200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAV54_08205	COG1105	Belongs to the carbohydrate kinase PfkB family
EAV54_08210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAV54_08210	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAV54_08240	COG0024	Methionine aminopeptidase
EAV54_08245	COG0583	DNA-binding transcription factor activity
EAV54_08255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EAV54_08260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAV54_08265	COG0517	IMP dehydrogenase activity
EAV54_08265	COG0516	GMP reductase activity
EAV54_08290	COG0552	protein localization to endoplasmic reticulum
EAV54_08300	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EAV54_08315	COG4890	Cyd operon protein YbgT
EAV54_08320	COG1294	oxidase, subunit
EAV54_08335	COG1585	Membrane protein implicated in regulation of membrane protease activity
EAV54_08345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAV54_08350	COG4774	siderophore transport
EAV54_08365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAV54_08370	COG0569	domain protein
EAV54_08375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAV54_08405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EAV54_08410	COG0542	response to heat
EAV54_08435	COG1902	pentaerythritol trinitrate reductase activity
EAV54_08435	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAV54_08480	COG2323	membrane
EAV54_08485	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EAV54_08495	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EAV54_08500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAV54_08505	COG0183	Belongs to the thiolase family
EAV54_08510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EAV54_08515	COG0596	Alpha beta hydrolase
EAV54_08520	COG2271	Major facilitator Superfamily
EAV54_08525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAV54_08530	COG3485	protocatechuate 3,4-dioxygenase
EAV54_08535	COG3485	protocatechuate 3,4-dioxygenase
EAV54_08540	COG0710	3-dehydroquinate dehydratase activity
EAV54_08545	COG3420	alginic acid biosynthetic process
EAV54_08550	COG3659	wide pore channel activity
EAV54_08555	COG4993	Dehydrogenase
EAV54_08565	COG2391	methyltransferase activity
EAV54_08580	COG1414	Transcriptional regulator
EAV54_08585	COG0583	DNA-binding transcription factor activity
EAV54_08590	COG1960	acyl-CoA dehydrogenase activity
EAV54_08615	COG2814	Major facilitator Superfamily
EAV54_08625	COG0154	amidase activity
EAV54_08645	COG4638	Rieske (2fe-2S)
EAV54_08655	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_08665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAV54_08675	COG3733	amine oxidase
EAV54_08685	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_08695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAV54_08700	COG0183	Belongs to the thiolase family
EAV54_08705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAV54_08710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EAV54_08720	COG4829	muconolactone delta-isomerase
EAV54_08725	COG4948	Mandelate Racemase Muconate Lactonizing
EAV54_08730	COG0583	DNA-binding transcription factor activity
EAV54_08740	COG2186	Transcriptional regulator
EAV54_08760	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_08775	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAV54_08775	COG1902	pentaerythritol trinitrate reductase activity
EAV54_08785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EAV54_08795	COG0789	Transcriptional regulator
EAV54_08820	COG1309	transcriptional regulator
EAV54_08825	COG0583	DNA-binding transcription factor activity
EAV54_08830	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_08835	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_08840	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_08850	COG1960	acyl-CoA dehydrogenase activity
EAV54_08860	COG0318	PFAM AMP-dependent synthetase and ligase
EAV54_08950	COG2188	Transcriptional regulator
EAV54_08965	COG0583	DNA-binding transcription factor activity
EAV54_08980	COG1566	PFAM secretion protein HlyD family protein
EAV54_08995	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_09000	COG0129	dihydroxy-acid dehydratase activity
EAV54_09010	COG0583	DNA-binding transcription factor activity
EAV54_09015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAV54_09025	COG2084	Dehydrogenase
EAV54_09030	COG2207	Transcriptional regulator
EAV54_09035	COG1064	alcohol dehydrogenase
EAV54_09045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAV54_09050	COG1120	ATPase activity
EAV54_09145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EAV54_09185	COG2856	Zn peptidase
EAV54_09240	COG2207	Transcriptional regulator
EAV54_09255	COG2205	protein histidine kinase activity
EAV54_09260	COG0745	RESPONSE REGULATOR receiver
EAV54_09265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAV54_09270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAV54_09360	COG3539	Fimbrial protein
EAV54_09385	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EAV54_09395	COG0753	catalase activity
EAV54_09410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAV54_09475	COG3433	isochorismatase activity
EAV54_09475	COG1535	isochorismatase
EAV54_09480	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_09485	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EAV54_09490	COG4149	molybdate abc transporter
EAV54_09495	COG0725	ABC transporter, periplasmic molybdate-binding protein
EAV54_09505	COG4638	Rieske (2fe-2S)
EAV54_09510	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EAV54_09515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAV54_09515	COG0543	2 iron, 2 sulfur cluster binding
EAV54_09530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAV54_09540	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_09555	COG2207	Transcriptional regulator
EAV54_09560	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_09565	COG2610	gluconate transmembrane transporter activity
EAV54_09575	COG1309	transcriptional regulator
EAV54_09595	COG0583	DNA-binding transcription factor activity
EAV54_09610	COG2031	fatty acid transporter
EAV54_09615	COG0183	Belongs to the thiolase family
EAV54_09620	COG0583	DNA-binding transcription factor activity
EAV54_09625	COG0583	DNA-binding transcription factor activity
EAV54_09640	COG1027	Aspartate ammonia-lyase
EAV54_09650	COG0477	Major facilitator Superfamily
EAV54_09670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAV54_09675	COG4521	taurine ABC transporter
EAV54_09690	COG2188	Transcriptional regulator
EAV54_09700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EAV54_09705	COG1733	regulation of RNA biosynthetic process
EAV54_09710	COG2207	Transcriptional regulator
EAV54_09710	COG3708	Transcriptional regulator
EAV54_09725	COG0730	response to heat
EAV54_09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAV54_09735	COG3453	Protein conserved in bacteria
EAV54_09745	COG3781	membrane
EAV54_09750	COG1063	alcohol dehydrogenase
EAV54_09760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAV54_09765	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAV54_09770	COG0022	dehydrogenase e1 component
EAV54_09775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EAV54_09780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EAV54_09795	COG3706	GGDEF domain
EAV54_09810	COG0133	tryptophan synthase activity
EAV54_09820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAV54_09850	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EAV54_09855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EAV54_09880	COG2226	methyltransferase
EAV54_09935	COG0842	Transport permease protein
EAV54_09940	COG0842	Transport permease protein
EAV54_09945	COG1131	(ABC) transporter
EAV54_09960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAV54_09965	COG4773	Receptor
EAV54_09985	COG0730	response to heat
EAV54_09990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAV54_10005	COG0406	alpha-ribazole phosphatase activity
EAV54_10010	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EAV54_10060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAV54_10070	COG4264	IucA IucC family
EAV54_10075	COG4264	IucA IucC family
EAV54_10080	COG2814	Major facilitator Superfamily
EAV54_10095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAV54_10110	COG1960	acyl-CoA dehydrogenase activity
EAV54_10115	COG1960	acyl-CoA dehydrogenase activity
EAV54_10120	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAV54_10125	COG2207	Transcriptional regulator
EAV54_10130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAV54_10135	COG0776	regulation of translation
EAV54_10160	COG0822	iron-sulfur transferase activity
EAV54_10165	COG0316	Belongs to the HesB IscA family
EAV54_10195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAV54_10215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAV54_10220	COG0702	epimerase
EAV54_10255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAV54_10265	COG0339	signal peptide processing
EAV54_10315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EAV54_10425	COG4695	Portal protein
EAV54_10580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAV54_10610	COG0776	regulation of translation
EAV54_10675	COG0084	hydrolase, TatD family'
EAV54_10695	COG1663	tetraacyldisaccharide 4'-kinase activity
EAV54_10700	COG1132	(ABC) transporter
EAV54_10710	COG0811	peptide transport
EAV54_10715	COG1475	DNA binding
EAV54_10720	COG1192	Involved in chromosome partitioning
EAV54_10730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EAV54_10745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAV54_10750	COG0191	fructose-bisphosphate aldolase activity
EAV54_10770	COG0424	maF-like protein
EAV54_10775	COG2850	peptidyl-arginine hydroxylation
EAV54_10785	COG0640	Transcriptional regulator
EAV54_10795	COG3619	membrane
EAV54_10800	COG3122	Protein conserved in bacteria
EAV54_10805	COG1132	(ABC) transporter
EAV54_10825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EAV54_10830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAV54_10840	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAV54_10840	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAV54_10840	COG0506	proline dehydrogenase activity
EAV54_10845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EAV54_10860	COG3698	Phosphodiester glycosidase
EAV54_10870	COG2353	YceI-like domain
EAV54_10880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAV54_10925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAV54_10925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EAV54_10950	COG3539	Fimbrial protein
EAV54_10955	COG3121	Chaperone
EAV54_10985	COG0697	spore germination
EAV54_10995	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EAV54_11005	COG0583	DNA-binding transcription factor activity
EAV54_11025	COG1309	transcriptional regulator
EAV54_11040	COG1522	sequence-specific DNA binding
EAV54_11050	COG1126	abc transporter atp-binding protein
EAV54_11055	COG0765	amino acid transport
EAV54_11060	COG0765	amino acid transport
EAV54_11090	COG1464	Belongs to the NlpA lipoprotein family
EAV54_11100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAV54_11105	COG2011	ABC-type metal ion transport system permease component
EAV54_11110	COG0012	GTP binding
EAV54_11135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EAV54_11175	COG0386	Belongs to the glutathione peroxidase family
EAV54_11185	COG0436	Aminotransferase
EAV54_11190	COG1301	dicarboxylic acid transport
EAV54_11225	COG3634	alkyl hydroperoxide reductase activity
EAV54_11240	COG0583	DNA-binding transcription factor activity
EAV54_11245	COG0798	PFAM Bile acid sodium symporter
EAV54_11250	COG0640	Transcriptional regulator
EAV54_11265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EAV54_11275	COG0583	DNA-binding transcription factor activity
EAV54_11285	COG1953	Uracil, thiamine, allantoin
EAV54_11295	COG2175	clavaminate synthase activity
EAV54_11300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAV54_11305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EAV54_11310	COG4521	taurine ABC transporter
EAV54_11320	COG0477	Major facilitator Superfamily
EAV54_11345	COG1271	oxidase subunit
EAV54_11350	COG1294	oxidase, subunit
EAV54_11360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAV54_11380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EAV54_11400	COG3052	prosthetic group binding
EAV54_11405	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EAV54_11415	COG0583	DNA-binding transcription factor activity
EAV54_11425	COG2814	Major facilitator Superfamily
EAV54_11440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAV54_11445	COG1346	cytolysis
EAV54_11455	COG0583	DNA-binding transcription factor activity
EAV54_11460	COG0625	glutathione transferase activity
EAV54_11465	COG0625	glutathione transferase activity
EAV54_11470	COG0583	DNA-binding transcription factor activity
EAV54_11485	COG1045	serine acetyltransferase
EAV54_11490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAV54_11495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAV54_11520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAV54_11525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAV54_11535	COG0765	amino acid transport
EAV54_11540	COG0765	amino acid transport
EAV54_11560	COG2205	protein histidine kinase activity
EAV54_11560	COG0784	Response regulator, receiver
EAV54_11600	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_11645	COG0583	DNA-binding transcription factor activity
EAV54_11665	COG0318	PFAM AMP-dependent synthetase and ligase
EAV54_11670	COG1309	transcriptional regulator
EAV54_11675	COG1960	acyl-CoA dehydrogenase activity
EAV54_11680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EAV54_11685	COG1024	Enoyl-CoA hydratase
EAV54_11690	COG4770	biotin carboxylase activity
EAV54_11700	COG0583	DNA-binding transcription factor activity
EAV54_11720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAV54_11725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EAV54_11740	COG3842	ATPase activity
EAV54_11745	COG1840	ABC-type Fe3 transport system, periplasmic component
EAV54_11760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAV54_11765	COG1414	Transcriptional regulator
EAV54_11775	COG0583	DNA-binding transcription factor activity
EAV54_11780	COG3038	cytochrome b561
EAV54_11785	COG0753	catalase activity
EAV54_11820	COG2050	protein possibly involved in aromatic compounds catabolism
EAV54_11830	COG3327	negative regulation of DNA-templated transcription, initiation
EAV54_11835	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EAV54_11840	COG0183	Belongs to the thiolase family
EAV54_11845	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAV54_11850	COG1024	Enoyl-CoA hydratase
EAV54_11855	COG1024	Enoyl-CoA hydratase
EAV54_11860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAV54_11865	COG2151	metal-sulfur cluster biosynthetic enzyme
EAV54_11870	COG3396	Phenylacetate-CoA oxygenase
EAV54_11875	COG3460	Phenylacetate-CoA oxygenase
EAV54_11880	COG3396	Phenylacetate-CoA oxygenase
EAV54_11885	COG2030	dehydratase
EAV54_11885	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_11890	COG1760	l-serine dehydratase
EAV54_11895	COG0531	amino acid
EAV54_11900	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_11925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAV54_11945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAV54_11960	COG0789	Transcriptional regulator
EAV54_11970	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAV54_11985	COG2807	transmembrane transport
EAV54_11990	COG0590	tRNA wobble adenosine to inosine editing
EAV54_12095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EAV54_12120	COG1116	anion transmembrane transporter activity
EAV54_12125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAV54_12135	COG0864	Transcriptional regulator
EAV54_12150	COG1733	regulation of RNA biosynthetic process
EAV54_12155	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAV54_12160	COG0439	Biotin carboxylase
EAV54_12175	COG1063	alcohol dehydrogenase
EAV54_12185	COG1309	transcriptional regulator
EAV54_12200	COG0038	chloride channel
EAV54_12205	COG4770	biotin carboxylase activity
EAV54_12225	COG1914	H( )-stimulated, divalent metal cation uptake system
EAV54_12230	COG0583	DNA-binding transcription factor activity
EAV54_12265	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAV54_12285	COG2814	Major facilitator Superfamily
EAV54_12305	COG0598	Magnesium transport protein CorA
EAV54_12310	COG1560	Kdo2-lipid A biosynthetic process
EAV54_12325	COG1522	sequence-specific DNA binding
EAV54_12340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EAV54_12350	COG4122	O-methyltransferase activity
EAV54_12380	COG1538	Outer membrane efflux protein
EAV54_12385	COG1137	ATPase activity
EAV54_12390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EAV54_12400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EAV54_12405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAV54_12405	COG0517	IMP dehydrogenase activity
EAV54_12445	COG2814	Major facilitator Superfamily
EAV54_12485	COG1278	Cold shock
EAV54_12490	COG1280	lysine exporter protein (LysE YggA)
EAV54_12525	COG1570	exodeoxyribonuclease VII activity
EAV54_12580	COG0583	DNA-binding transcription factor activity
EAV54_12585	COG4638	Rieske (2fe-2S)
EAV54_12590	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EAV54_12595	COG0543	2 iron, 2 sulfur cluster binding
EAV54_12595	COG0633	Ferredoxin
EAV54_12600	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_12605	COG3135	benzoate transporter
EAV54_12610	COG2814	Major facilitator Superfamily
EAV54_12625	COG1643	Atp-dependent helicase
EAV54_12630	COG0450	alkyl hydroperoxide reductase
EAV54_12640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EAV54_12650	COG3634	alkyl hydroperoxide reductase activity
EAV54_12670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EAV54_12675	COG0625	glutathione transferase activity
EAV54_12685	COG2885	chlorophyll binding
EAV54_12720	COG0542	response to heat
EAV54_12735	COG1765	OsmC-like protein
EAV54_12745	COG0667	Aldo Keto reductase
EAV54_12760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EAV54_12780	COG0582	viral genome integration into host DNA
EAV54_12920	COG3566	protein conserved in bacteria
EAV54_12945	COG3567	Phage-associated protein, HI1409 family
EAV54_12950	COG5410	chromosome segregation
EAV54_13030	COG4197	protein conserved in bacteria, prophage-related
EAV54_13035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAV54_13085	COG0527	aspartate kinase activity
EAV54_13095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EAV54_13105	COG3038	cytochrome b561
EAV54_13110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EAV54_13115	COG2252	PERMEase
EAV54_13125	COG2072	flavoprotein involved in K transport
EAV54_13140	COG1741	Belongs to the pirin family
EAV54_13145	COG1309	transcriptional regulator
EAV54_13155	COG0300	oxidoreductase activity
EAV54_13160	COG2072	flavoprotein involved in K transport
EAV54_13165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EAV54_13210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAV54_13225	COG2814	Major facilitator Superfamily
EAV54_13230	COG1024	Enoyl-CoA hydratase
EAV54_13235	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_13245	COG1960	acyl-CoA dehydrogenase activity
EAV54_13270	COG2186	Transcriptional regulator
EAV54_13275	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_13285	COG4948	Mandelate Racemase Muconate Lactonizing
EAV54_13290	COG2271	Major facilitator Superfamily
EAV54_13295	COG2721	sulfolactate sulfo-lyase activity
EAV54_13300	COG0697	spore germination
EAV54_13330	COG1113	amino acid transport
EAV54_13350	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_13370	COG0531	amino acid
EAV54_13380	COG1113	amino acid transport
EAV54_13425	COG0583	DNA-binding transcription factor activity
EAV54_13435	COG0251	oxidation-reduction process
EAV54_13475	COG1902	pentaerythritol trinitrate reductase activity
EAV54_13475	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAV54_13490	COG2203	Gaf domain
EAV54_13490	COG3706	GGDEF domain
EAV54_13490	COG4251	negative regulation of phosphorylation
EAV54_13490	COG5001	Diguanylate cyclase
EAV54_13500	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAV54_13520	COG4172	Belongs to the ABC transporter superfamily
EAV54_13525	COG4239	(ABC) transporter, permease
EAV54_13530	COG4174	ABC transporter (Permease)
EAV54_13540	COG0741	lytic transglycosylase activity
EAV54_13540	COG0741	lytic transglycosylase activity
EAV54_13540	COG1388	LysM domain
EAV54_13540	COG1388	LysM domain
EAV54_13545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAV54_13585	COG0583	DNA-binding transcription factor activity
EAV54_13590	COG1279	arginine transmembrane transporter activity
EAV54_13610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAV54_13615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAV54_13620	COG0006	proline dipeptidase activity
EAV54_13660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAV54_13685	COG3384	dioxygenase
EAV54_13695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAV54_13700	COG2878	Part of a membrane complex involved in electron transport
EAV54_13705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAV54_13725	COG0768	penicillin binding
EAV54_13730	COG0742	ribosomal rna small subunit methyltransferase
EAV54_13745	COG0830	nickel cation binding
EAV54_13755	COG0804	urea catabolic process
EAV54_13800	COG1253	flavin adenine dinucleotide binding
EAV54_13810	COG2851	Citrate transporter
EAV54_13860	COG1773	rubredoxin
EAV54_13865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAV54_13875	COG0583	DNA-binding transcription factor activity
EAV54_13905	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EAV54_13910	COG4181	ATPase activity
EAV54_13955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EAV54_13975	COG0306	phosphate transporter
EAV54_13990	COG3958	Transketolase
EAV54_13995	COG3959	Transketolase, thiamine diphosphate binding domain
EAV54_14000	COG2271	Major facilitator Superfamily
EAV54_14005	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_14010	COG0583	DNA-binding transcription factor activity
EAV54_14035	COG2223	nitrite transmembrane transporter activity
EAV54_14040	COG2207	Transcriptional regulator
EAV54_14045	COG2066	Belongs to the glutaminase family
EAV54_14050	COG0242	peptide deformylase activity
EAV54_14055	COG0477	Major facilitator Superfamily
EAV54_14065	COG0028	Belongs to the TPP enzyme family
EAV54_14080	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_14085	COG2267	carboxylic ester hydrolase activity
EAV54_14095	COG2271	Major facilitator Superfamily
EAV54_14100	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAV54_14110	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_14130	COG1414	Transcriptional regulator
EAV54_14145	COG1024	Enoyl-CoA hydratase
EAV54_14155	COG1215	transferase activity, transferring glycosyl groups
EAV54_14160	COG1649	PFAM Uncharacterised BCR, COG1649
EAV54_14160	COG0726	polysaccharide deacetylase
EAV54_14170	COG4681	YaeQ
EAV54_14180	COG0523	cobalamin synthesis protein
EAV54_14190	COG1607	acyl-coa hydrolase
EAV54_14200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAV54_14205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAV54_14210	COG1309	transcriptional regulator
EAV54_14235	COG2040	homocysteine
EAV54_14240	COG0531	amino acid
EAV54_14265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAV54_14270	COG0477	Major facilitator Superfamily
EAV54_14310	COG0405	Gamma-glutamyltransferase
EAV54_14315	COG2814	Major facilitator Superfamily
EAV54_14325	COG2050	protein possibly involved in aromatic compounds catabolism
EAV54_14340	COG1090	epimerase
EAV54_14360	COG0420	3'-5' exonuclease activity
EAV54_14385	COG0735	belongs to the Fur family
EAV54_14390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAV54_14415	COG0121	glutamine amidotransferase
EAV54_14430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAV54_14440	COG0210	DNA helicase
EAV54_14445	COG2885	chlorophyll binding
EAV54_14450	COG0204	Acyl-transferase
EAV54_14465	COG2894	cell division
EAV54_14480	COG1280	lysine exporter protein (LysE YggA)
EAV54_14485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAV54_14485	COG1674	ftsk spoiiie
EAV54_14490	COG0492	ferredoxin-NADP+ reductase activity
EAV54_14495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EAV54_14505	COG0456	acetyltransferase
EAV54_14550	COG1981	membrane
EAV54_14565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EAV54_14565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAV54_14585	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_14595	COG0657	acetylesterase activity
EAV54_14605	COG0473	3-isopropylmalate dehydrogenase activity
EAV54_14610	COG0583	DNA-binding transcription factor activity
EAV54_14630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAV54_14655	COG0564	pseudouridine synthase activity
EAV54_14665	COG0358	DNA primase activity
EAV54_14680	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EAV54_14710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAV54_14740	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EAV54_14750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EAV54_14750	COG0351	phosphomethylpyrimidine kinase
EAV54_14750	COG0352	thiamine-phosphate diphosphorylase activity
EAV54_14755	COG1652	LysM domain
EAV54_14780	COG1399	metal-binding, possibly nucleic acid-binding protein
EAV54_14785	COG3101	peptidyl-lysine hydroxylation
EAV54_14790	COG0009	L-threonylcarbamoyladenylate synthase
EAV54_14795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EAV54_14800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EAV54_14815	COG4106	trans-aconitate 2-methyltransferase activity
EAV54_14830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAV54_14830	COG2226	methyltransferase
EAV54_14830	COG0596	Alpha beta hydrolase
EAV54_14835	COG1877	trehalose-phosphatase activity
EAV54_14840	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EAV54_14845	COG2223	nitrite transmembrane transporter activity
EAV54_14865	COG1196	nuclear chromosome segregation
EAV54_14875	COG0730	response to heat
EAV54_14890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAV54_14900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAV54_14960	COG0489	protein tyrosine kinase activity
EAV54_14970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAV54_14970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAV54_15000	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EAV54_15005	COG2081	HI0933 family
EAV54_15015	COG0668	transmembrane transport
EAV54_15035	COG0583	DNA-binding transcription factor activity
EAV54_15060	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAV54_15065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAV54_15095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EAV54_15135	COG0745	RESPONSE REGULATOR receiver
EAV54_15150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAV54_15200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAV54_15215	COG0583	DNA-binding transcription factor activity
EAV54_15245	COG0583	DNA-binding transcription factor activity
EAV54_15265	COG0583	DNA-binding transcription factor activity
EAV54_15270	COG1053	succinate dehydrogenase
EAV54_15280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAV54_15285	COG2814	Major facilitator Superfamily
EAV54_15290	COG1960	acyl-CoA dehydrogenase activity
EAV54_15295	COG0583	DNA-binding transcription factor activity
EAV54_15300	COG1063	alcohol dehydrogenase
EAV54_15330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EAV54_15335	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EAV54_15340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAV54_15360	COG2132	Multicopper oxidase
EAV54_15370	COG0561	phosphatase activity
EAV54_15375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAV54_15400	COG1214	PFAM Peptidase M22, glycoprotease
EAV54_15450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EAV54_15460	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EAV54_15465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EAV54_15470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EAV54_15530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAV54_15540	COG1846	Transcriptional regulator
EAV54_15545	COG1764	response to oxidative stress
EAV54_15585	COG0037	tRNA processing
EAV54_15595	COG0248	Ppx GppA phosphatase
EAV54_15625	COG0072	phenylalanine-tRNA ligase activity
EAV54_15665	COG1238	metal cluster binding
EAV54_15670	COG0625	glutathione transferase activity
EAV54_15690	COG0318	PFAM AMP-dependent synthetase and ligase
EAV54_15695	COG3028	Belongs to the UPF0307 family
EAV54_15700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAV54_15720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EAV54_15725	COG0617	tRNA 3'-terminal CCA addition
EAV54_15730	COG1555	photosystem II stabilization
EAV54_15735	COG3956	TIGRFAM MazG family protein
EAV54_15745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAV54_15765	COG0784	Response regulator, receiver
EAV54_15765	COG2205	protein histidine kinase activity
EAV54_15765	COG5002	protein histidine kinase activity
EAV54_15770	COG1024	Enoyl-CoA hydratase
EAV54_15775	COG2084	Dehydrogenase
EAV54_15780	COG3622	Belongs to the hyi family
EAV54_15810	COG0697	spore germination
EAV54_15820	COG2814	Major facilitator Superfamily
EAV54_15825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAV54_15835	COG0583	DNA-binding transcription factor activity
EAV54_15845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EAV54_15855	COG0084	hydrolase, TatD family'
EAV54_15870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EAV54_15925	COG0440	acetolactate synthase activity
EAV54_15930	COG0028	Belongs to the TPP enzyme family
EAV54_15955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAV54_15960	COG0577	efflux transmembrane transporter activity
EAV54_15960	COG1136	(ABC) transporter
EAV54_15965	COG1538	Outer membrane efflux protein
EAV54_15980	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EAV54_15985	COG1162	GTPase activity
EAV54_15995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAV54_16015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAV54_16020	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_16060	COG2986	histidine ammonia-lyase
EAV54_16070	COG1216	Glycosyl transferase, family 2
EAV54_16075	COG0318	PFAM AMP-dependent synthetase and ligase
EAV54_16085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAV54_16130	COG1426	Protein conserved in bacteria
EAV54_16165	COG0793	Belongs to the peptidase S41A family
EAV54_16180	COG2267	carboxylic ester hydrolase activity
EAV54_16190	COG1012	belongs to the aldehyde dehydrogenase family
EAV54_16195	COG3265	gluconokinase activity
EAV54_16205	COG0800	Aldolase
EAV54_16215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAV54_16220	COG0280	phosphate acetyltransferase
EAV54_16220	COG0857	belongs to the CobB CobQ family
EAV54_16225	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAV54_16225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAV54_16245	COG0740	serine-type endopeptidase activity
EAV54_16255	COG4774	siderophore transport
EAV54_16265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAV54_16275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAV54_16275	COG2813	Specifically methylates the guanine in position
EAV54_16375	COG0788	formyltetrahydrofolate deformylase activity
EAV54_16400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAV54_16400	COG4651	solute:proton antiporter activity
EAV54_16420	COG0724	RNA recognition motif
EAV54_16425	COG0210	DNA helicase
EAV54_16450	COG1733	regulation of RNA biosynthetic process
EAV54_16460	COG2900	Belongs to the SlyX family
EAV54_16465	COG0488	(ABC) transporter
EAV54_16470	COG1280	lysine exporter protein (LysE YggA)
EAV54_16475	COG1560	Kdo2-lipid A biosynthetic process
EAV54_16485	COG1301	dicarboxylic acid transport
EAV54_16540	COG0473	3-isopropylmalate dehydrogenase activity
EAV54_16595	COG0583	DNA-binding transcription factor activity
EAV54_16605	COG0625	glutathione transferase activity
EAV54_16610	COG2378	regulation of single-species biofilm formation
EAV54_16615	COG0546	phosphoglycolate phosphatase activity
EAV54_16630	COG1530	ribonuclease E activity
EAV54_16635	COG0318	PFAM AMP-dependent synthetase and ligase
EAV54_16650	COG0583	DNA-binding transcription factor activity
EAV54_16655	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_16660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAV54_16670	COG0534	Mate efflux family protein
EAV54_16685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EAV54_16710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAV54_16710	COG0493	'glutamate synthase
EAV54_16720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EAV54_16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAV54_16740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EAV54_16750	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EAV54_16750	COG0644	oxidoreductase
EAV54_16760	COG0425	Belongs to the sulfur carrier protein TusA family
EAV54_16765	COG4535	Mg2 and Co2 transporter CorC
EAV54_16775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAV54_16795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EAV54_16800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAV54_16800	COG0475	glutathione-regulated potassium exporter activity
EAV54_16815	COG0484	heat shock protein binding
EAV54_16820	COG0789	Transcriptional regulator
EAV54_16825	COG0598	Magnesium transport protein CorA
EAV54_16840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAV54_16845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAV54_16850	COG1074	ATP-dependent DNA helicase activity
EAV54_16855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EAV54_16875	COG2226	methyltransferase
EAV54_16895	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EAV54_16910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAV54_16910	COG2111	Na H antiporter
EAV54_16915	COG1006	Multisubunit Na H antiporter MnhC subunit
EAV54_16920	COG0651	ATP synthesis coupled electron transport
EAV54_16925	COG1863	multisubunit Na H antiporter MnhE subunit
EAV54_16930	COG2212	antiporter activity
EAV54_16935	COG1320	monovalent cation:proton antiporter activity
EAV54_16950	COG0195	Participates in both transcription termination and antitermination
EAV54_17000	COG0237	dephospho-CoA kinase activity
EAV54_17010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAV54_17025	COG0497	DNA recombination
EAV54_17035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EAV54_17065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAV54_17065	COG2169	Transcriptional regulator
EAV54_17070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EAV54_17140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EAV54_17155	COG0326	Molecular chaperone. Has ATPase activity
EAV54_17170	COG2056	Na+-H+ antiporter family
EAV54_17175	COG0596	Alpha beta hydrolase
EAV54_17270	COG0546	phosphoglycolate phosphatase activity
EAV54_17275	COG1716	ATPase activity
EAV54_17320	COG0181	hydroxymethylbilane synthase activity
EAV54_17330	COG3275	phosphorelay sensor kinase activity
EAV54_17350	COG1538	Outer membrane efflux protein
EAV54_17355	COG0697	spore germination
EAV54_17380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EAV54_17385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAV54_17390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAV54_17395	COG0772	Belongs to the SEDS family
EAV54_17420	COG4974	Belongs to the 'phage' integrase family
EAV54_17425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAV54_17435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EAV54_17445	COG2197	response regulator
EAV54_17460	COG0793	Belongs to the peptidase S41A family
EAV54_17465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EAV54_17470	COG0795	lipopolysaccharide-transporting ATPase activity
EAV54_17510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAV54_17510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAV54_17520	COG0004	ammonium transporteR
EAV54_17525	COG0347	Belongs to the P(II) protein family
EAV54_17535	COG0606	chelatase, subunit chli
EAV54_17545	COG0659	secondary active sulfate transmembrane transporter activity
EAV54_17550	COG0589	response to stress
EAV54_17600	COG0606	chelatase, subunit chli
EAV54_17605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAV54_17615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAV54_17630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EAV54_17645	COG0318	PFAM AMP-dependent synthetase and ligase
EAV54_17655	COG0477	Major facilitator Superfamily
EAV54_17660	COG2860	membrane
EAV54_17665	COG3012	SEC-C Motif Domain Protein
EAV54_17670	COG1253	flavin adenine dinucleotide binding
EAV54_17680	COG0477	Major facilitator Superfamily
EAV54_17690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAV54_17725	COG0655	NAD(P)H dehydrogenase (quinone) activity
EAV54_17735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EAV54_17770	COG1309	transcriptional regulator
EAV54_17805	COG0758	DNA mediated transformation
EAV54_17815	COG0697	spore germination
EAV54_17820	COG1309	transcriptional regulator
EAV54_17835	COG0386	Belongs to the glutathione peroxidase family
EAV54_17905	COG1121	(ABC) transporter
EAV54_17910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAV54_17915	COG1280	lysine exporter protein (LysE YggA)
EAV54_17920	COG2837	iron assimilation
EAV54_17925	COG0281	malic enzyme
EAV54_17970	COG0519	Catalyzes the synthesis of GMP from XMP
EAV54_17970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAV54_17975	COG4399	Belongs to the UPF0754 family
EAV54_17980	COG2259	Doxx family
EAV54_17985	COG0586	Pfam SNARE associated Golgi protein
EAV54_18000	COG1192	Involved in chromosome partitioning
EAV54_18010	COG0271	Belongs to the BolA IbaG family
EAV54_18050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAV54_18050	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EAV54_18050	COG3321	synthase
EAV54_18050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAV54_18055	COG1960	acyl-CoA dehydrogenase activity
EAV54_18060	COG0318	PFAM AMP-dependent synthetase and ligase
EAV54_18065	COG2197	response regulator
EAV54_18075	COG3916	Acyl-homoserine-lactone synthase
EAV54_18080	COG0477	Major facilitator Superfamily
EAV54_18085	COG1024	Enoyl-CoA hydratase
EAV54_18090	COG1024	Enoyl-CoA hydratase
EAV54_18095	COG1960	acyl-CoA dehydrogenase activity
EAV54_18100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAV54_18120	COG1113	amino acid transport
EAV54_18125	COG1113	amino acid transport
EAV54_18130	COG0251	oxidation-reduction process
EAV54_18170	COG0564	pseudouridine synthase activity
EAV54_18250	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAV54_18265	COG1802	Transcriptional regulator
EAV54_18275	COG1448	Aminotransferase
EAV54_18280	COG0277	FAD linked oxidase domain protein
EAV54_18290	COG2186	Transcriptional regulator
EAV54_18300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAV54_18305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAV54_18320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EAV54_18325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EAV54_18350	COG0438	transferase activity, transferring glycosyl groups
EAV54_18380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EAV54_18410	COG0728	peptidoglycan biosynthetic process
EAV54_18415	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAV54_18470	COG0546	phosphoglycolate phosphatase activity
EAV54_18475	COG1028	Short-chain dehydrogenase reductase Sdr
EAV54_18495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAV54_18500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAV54_18505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAV54_18510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAV54_18515	COG1116	anion transmembrane transporter activity
EAV54_18520	COG1309	transcriptional regulator
EAV54_18525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAV54_18535	COG0196	riboflavin kinase activity
EAV54_18540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EAV54_18550	COG1047	Peptidyl-prolyl cis-trans
EAV54_18590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAV54_18595	COG0657	acetylesterase activity
EAV54_18645	COG2951	lytic endotransglycosylase activity
EAV54_18650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAV54_18670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAV54_18680	COG0671	phosphoesterase, PA-phosphatase related
EAV54_18685	COG0861	Integral membrane protein TerC family
EAV54_18695	COG0754	glutathionylspermidine amidase activity
EAV54_18705	COG0402	S-adenosylhomocysteine deaminase activity
EAV54_18720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAV54_18725	COG1230	cation diffusion facilitator family transporter
EAV54_18740	COG0706	membrane insertase activity
EAV54_18770	COG4691	Plasmid stability protein
EAV54_18805	COG0798	PFAM Bile acid sodium symporter
EAV54_18845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAV54_18895	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EAV54_18925	COG0659	secondary active sulfate transmembrane transporter activity
EAV54_18930	COG0589	response to stress
EAV54_18990	COG0501	Belongs to the peptidase M48B family
EAV54_19180	COG0739	heme binding
EAV54_19210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAV54_19225	COG1192	Involved in chromosome partitioning
EAV54_19275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAV54_19410	COG1525	nuclease
EAV54_19490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAV54_19520	COG0640	Transcriptional regulator